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Tytuł:
Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling.
Autorzy:
Zhang Y; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Young R; Chester Beatty Laboratories, Structural Biology Division, Institute of Cancer Research, London, UK.
Garvanska DH; The NNF Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.
Song C; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Zhai Y; School of Public Health, Qingdao University, Qingdao, China.
Wang Y; School of Public Health, Qingdao University, Qingdao, China.
Jiang H; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Fang J; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Nilsson J; The NNF Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.
Alfieri C; Chester Beatty Laboratories, Structural Biology Division, Institute of Cancer Research, London, UK. .
Zhang G; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China. zhanggang_.
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Źródło:
Communications biology [Commun Biol] 2024 Feb 09; Vol. 7 (1), pp. 164. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Cdc20 Proteins*/chemistry
Cdc20 Proteins*/genetics
Cdc20 Proteins*/metabolism
M Phase Cell Cycle Checkpoints*/genetics
Spindle Apparatus*/genetics
Spindle Apparatus*/metabolism
Anaphase-Promoting Complex-Cyclosome/genetics ; Anaphase-Promoting Complex-Cyclosome/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Signal Transduction ; Humans
Czasopismo naukowe
Tytuł:
Cell cycle specific, differentially tagged ribosomal proteins to measure phase specific transcriptomes from asynchronously cycling cells.
Autorzy:
Cochran JD; Medical Scientist Training Program, University of Virginia, Charlottesville, VA, USA.
Leathers TA; Department of Anatomy, Physiology, and Cell Biology, University of California, Davis, USA.
Maldosevic E; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, USA.
Siejda KW; Department of Medicine, University of Virginia, Charlottesville, VA, USA.
Vitello J; Department of Biomedical Engineering, University of Virginia, Charlottesville, VA, USA.
Lee H; Department of Medicine, University of Virginia, Charlottesville, VA, USA.
Bradley LA; Department of Medicine, University of Virginia, Charlottesville, VA, USA.; Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA.
Young A; Department of Medicine, University of Virginia, Charlottesville, VA, USA.; Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA.
Jomaa A; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, USA.
Wolf MJ; Department of Medicine, University of Virginia, Charlottesville, VA, USA. .; Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville, VA, USA. .; Division of Cardiology, University of Virginia, Medical Research Building 5 (MR5), Room G213, 415 Lane Road, Charlottesville, VA, 22908, USA. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 18; Vol. 14 (1), pp. 1623. Date of Electronic Publication: 2024 Jan 18.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Cycle Proteins*/genetics
Transcriptome*
Cell Cycle/genetics ; Ribosomal Proteins/genetics ; Ribosomes/genetics
Czasopismo naukowe
Tytuł:
A simple Turing reaction-diffusion model explains how PLK4 breaks symmetry during centriole duplication and assembly.
Autorzy:
Wilmott ZM; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.; Mathematical Institute, University of Oxford, Oxford, United Kingdom.
Goriely A; Mathematical Institute, University of Oxford, Oxford, United Kingdom.
Raff JW; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
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Źródło:
PLoS biology [PLoS Biol] 2023 Nov 20; Vol. 21 (11), pp. e3002391. Date of Electronic Publication: 2023 Nov 20 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Centrioles*/metabolism
Cell Cycle Proteins*/metabolism
Cell Cycle/physiology
Czasopismo naukowe
Tytuł:
Rif1 restrains the rate of replication origin firing in Xenopus laevis.
Autorzy:
Haccard O; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.
Ciardo D; Institut de Biologie de l'Ecole Normale Supérieure, Ecole Normale Supérieure, CNRS, INSERM, PSL Research University, Paris, France.
Narrissamprakash H; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.
Bronchain O; Paris-Saclay Institute of Neuroscience, CNRS, Université Paris-Saclay, CERTO-Retina France, 91400, Saclay, France.
Kumagai A; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
Dunphy WG; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
Goldar A; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.
Marheineke K; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France. .
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Źródło:
Communications biology [Commun Biol] 2023 Jul 29; Vol. 6 (1), pp. 788. Date of Electronic Publication: 2023 Jul 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Cycle Proteins*/genetics
Replication Origin*
Animals ; Cell Cycle ; Chromatin/genetics ; Xenopus laevis/genetics
Czasopismo naukowe
Tytuł:
Meiotic cells escape prolonged spindle checkpoint activity through kinetochore silencing and slippage.
Autorzy:
MacKenzie A; Department of Biology, Indiana University, Bloomington, Indiana, United States of America.
Vicory V; Department of Biology, Indiana University, Bloomington, Indiana, United States of America.
Lacefield S; Department of Biology, Indiana University, Bloomington, Indiana, United States of America.; Department of Biochemistry and Cell Biology, the Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2023 Apr 05; Vol. 19 (4), pp. e1010707. Date of Electronic Publication: 2023 Apr 05 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cell Cycle Checkpoints*
Kinetochores*/metabolism
Spindle Apparatus*/genetics
Spindle Apparatus*/metabolism
Meiosis*
Saccharomyces cerevisiae*/cytology
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Anaphase-Promoting Complex-Cyclosome/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Chromosome Segregation ; Germ Cells/metabolism ; Microtubules/genetics ; Microtubules/metabolism ; Mitosis
Czasopismo naukowe
Tytuł:
Anti-proliferative effect of melatonin in human hepatoma HepG2 cells occurs mainly through cell cycle arrest and inflammation inhibition.
Autorzy:
Nabih HK; Medical Biochemistry Department, Medicine and Clinical Studies Research Institute, National Research Centre, 33 El Bohouth St., Dokki, Giza, 12622, Egypt. .
Hamed AR; Chemistry of Medicinal Plants Department, and Biology Unit, Central Laboratory for Pharmaceutical and Drug Industries Research Institute, National Research Centre, 33 El Bohouth St., Dokki, Giza, 12622, Egypt.
Yahya SMM; Hormones Department, Medicine and Clinical Studies Research Institute, and Stem Cell Lab, Centre of Excellence for Advanced Sciences, National Research Centre, 33 El Bohouth St., Dokki, Giza, 12622, Egypt.
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Źródło:
Scientific reports [Sci Rep] 2023 Mar 16; Vol. 13 (1), pp. 4396. Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/metabolism
Cell Cycle Checkpoints*/drug effects
Inflammation*/drug therapy
Liver Neoplasms*/drug therapy
Liver Neoplasms*/metabolism
Melatonin*/pharmacology
Melatonin*/therapeutic use
Humans ; Apoptosis ; Cell Cycle ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Hep G2 Cells
Czasopismo naukowe
Tytuł:
CDT1 is the major functional regulatory subunit of the pre-replication complex in zygotes.
Autorzy:
Li C; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Tan YP; Fertility Preservation Lab, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China.
Ma XS; Reproductive Genetics Department, The Affiliated Tai'an City Central Hospital of Qingdao University, Taian, China.
Wang ZB; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Meng TG; Fertility Preservation Lab, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China.
Sun QY; Fertility Preservation Lab, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China.
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Źródło:
Cell proliferation [Cell Prolif] 2023 Mar; Vol. 56 (3), pp. e13377. Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Zygote*/metabolism
Cell Cycle Proteins*/metabolism
DNA Replication ; Cell Cycle ; DNA
Czasopismo naukowe
Tytuł:
Quiescent Cancer Cells-A Potential Therapeutic Target to Overcome Tumor Resistance and Relapse.
Autorzy:
Lindell E; Department of Immunology, Genetics and Pathology, Uppsala University, SE-751 85 Uppsala, Sweden.
Zhong L; Department of Immunology, Genetics and Pathology, Uppsala University, SE-751 85 Uppsala, Sweden.
Zhang X; Department of Immunology, Genetics and Pathology, Uppsala University, SE-751 85 Uppsala, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 13; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasm Recurrence, Local*/drug therapy
Resting Phase, Cell Cycle*/drug effects
Humans ; Cell Cycle ; Cell Division ; Recurrence
Czasopismo naukowe
Tytuł:
Septin 9 controls CCNB1 stabilization via APC/C during meiotic metaphase I/anaphase I transition in mouse oocytes.
Autorzy:
Chen L; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Ouyang YC; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Gu LJ; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Guo JN; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Han ZM; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Wang ZB; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Hou Y; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Schatten H; Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, USA.
Sun QY; Fertility Preservation Lab, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China.
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Źródło:
Cell proliferation [Cell Prolif] 2023 Feb; Vol. 56 (2), pp. e13359. Date of Electronic Publication: 2022 Nov 10.
Typ publikacji:
Journal Article
MeSH Terms:
Oocytes*/cytology
Oocytes*/metabolism
Septins*/genetics
Septins*/metabolism
Cell Cycle*
Animals ; Mice ; Anaphase ; Anaphase-Promoting Complex-Cyclosome/genetics ; Anaphase-Promoting Complex-Cyclosome/metabolism ; Cdc20 Proteins/genetics ; Cdc20 Proteins/metabolism ; Cell Cycle Proteins/metabolism ; Metaphase ; RNA, Messenger/metabolism ; RNA, Small Interfering/metabolism
Czasopismo naukowe
Tytuł:
Molecular basis for the recognition of CIZ1 by ERH.
Autorzy:
Wang X; MOE Key Laboratory for Cellular Dynamics, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Xie H; MOE Key Laboratory for Cellular Dynamics, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Zhu Z; MOE Key Laboratory for Cellular Dynamics, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Zhang J; MOE Key Laboratory for Cellular Dynamics, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Xu C; MOE Key Laboratory for Cellular Dynamics, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
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Źródło:
The FEBS journal [FEBS J] 2023 Feb; Vol. 290 (3), pp. 712-723. Date of Electronic Publication: 2022 Sep 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Transcription Factors*/genetics
Cell Cycle Proteins*/genetics
Humans ; Cell Cycle ; Genes, cdc ; Cell Division ; Nuclear Proteins/metabolism
Czasopismo naukowe
Tytuł:
Downregulation of CDC25C in NPCs Disturbed Cortical Neurogenesis.
Autorzy:
Zhou X; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, Fuzhou 350005, China.; College of Biological Science and Engineering, Institute of Life Sciences, Fuzhou University, Fuzhou 350108, China.
Lu D; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, Fuzhou 350005, China.; College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Yi W; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, Fuzhou 350005, China.; School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350108, China.
Xu D; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, Fuzhou 350005, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 12; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
cdc25 Phosphatases*/genetics
cdc25 Phosphatases*/metabolism
Cell Cycle Proteins*/genetics
Cell Cycle Proteins*/metabolism
Neurogenesis*/genetics
Neurogenesis*/physiology
Neural Stem Cells*/metabolism
Animals ; Rats ; Cell Cycle ; Cell Differentiation/genetics ; Cyclin-Dependent Kinases/metabolism ; Down-Regulation/genetics
Czasopismo naukowe
Tytuł:
The Anaphase-Promoting Complex/Cyclosome Is a Cellular Ageing Regulator.
Autorzy:
Hu X; State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou 311300, China.
Jin X; State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou 311300, China.
Cao X; State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou 311300, China.
Liu B; State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, Hangzhou 311300, China.; Department of Chemistry and Molecular Biology, University of Gothenburg, 41390 Gothenburg, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 05; Vol. 23 (23). Date of Electronic Publication: 2022 Dec 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cell Cycle Proteins*/metabolism
Cellular Senescence*/genetics
Humans ; Anaphase-Promoting Complex-Cyclosome/metabolism ; Cell Cycle
Czasopismo naukowe
Tytuł:
Neurobehavioral and developmental profiles: genotype-phenotype correlations in individuals with Cornelia de Lange syndrome.
Autorzy:
Ng R; Department of Neuropsychology, Kennedy Krieger Institute, 1750 E. Fairmount Ave, Baltimore, MD, 21231, USA. .; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA. .
O'Connor J; Department of Neuropsychology, Kennedy Krieger Institute, 1750 E. Fairmount Ave, Baltimore, MD, 21231, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Summa D; Cornelia de Lange Syndrome Foundation, Avon, CT, USA.
Kline AD; Harvey Institute for Human Genetics, Department of Pediatrics, Greater Baltimore Medical Center, Baltimore, MD, USA.
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Źródło:
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2024 Mar 10; Vol. 19 (1), pp. 111. Date of Electronic Publication: 2024 Mar 10.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Cycle Proteins*/genetics
De Lange Syndrome*/genetics
Child ; Adult ; Humans ; Young Adult ; Chromosomal Proteins, Non-Histone/genetics ; Phenotype ; Genetic Association Studies
Czasopismo naukowe
Tytuł:
Sister chromatid cohesion is mediated by individual cohesin complexes.
Autorzy:
Ochs F; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Green C; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Szczurek AT; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Pytowski L; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Kolesnikova S; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, 1030 Vienna Austria.
Brown J; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
Gerlich DW; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna Austria.
Buckle V; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.
Schermelleh L; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Nasmyth KA; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar 08; Vol. 383 (6687), pp. 1122-1130. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Cycle Proteins*/metabolism
Chromatids*/metabolism
Cohesins*/metabolism
Sister Chromatid Exchange*
Humans ; Chromatin/metabolism ; DNA/genetics ; DNA/metabolism ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.
Autorzy:
Finci LI; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Chakrabarti M; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Gulten G; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Finney J; National Cryo-EM Facility, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Grose C; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Fox T; National Cryo-EM Facility, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Yang R; Center for Molecular Microscopy, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Nissley DV; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
McCormick F; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
Esposito D; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Balius TE; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Simanshu DK; NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA. .
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Źródło:
Communications biology [Commun Biol] 2024 Mar 02; Vol. 7 (1), pp. 260. Date of Electronic Publication: 2024 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Cycle Proteins*/metabolism
Chaperonins*/chemistry
Humans ; Protein Binding ; Molecular Chaperones/metabolism ; HSP90 Heat-Shock Proteins
Czasopismo naukowe
Tytuł:
PARD3 drives tumorigenesis through activating Sonic Hedgehog signalling in tumour-initiating cells in liver cancer.
Autorzy:
Wu J; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Tan HY; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Centre for Chinese Medicine Drug Development, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
Chan YT; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Lu Y; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Feng Z; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Yuan H; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Zhang C; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Feng Y; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Wang N; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Feb 06; Vol. 43 (1), pp. 42. Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/metabolism
Carcinoma, Hepatocellular*/pathology
Cell Cycle Proteins*/metabolism
Liver Neoplasms*/pathology
Humans ; Carcinogenesis/metabolism ; Cell Line, Tumor ; Cell Transformation, Neoplastic/metabolism ; Choline/metabolism ; Hedgehog Proteins/genetics ; Hedgehog Proteins/metabolism ; Neoplastic Stem Cells/metabolism ; RNA, Guide, CRISPR-Cas Systems
Czasopismo naukowe
Tytuł:
Recovery from spindle checkpoint-mediated arrest requires a novel Dnt1-dependent APC/C activation mechanism.
Autorzy:
Bai S; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.
Sun L; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.
Wang X; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.
Wang SM; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.
Luo ZQ; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.
Wang Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.
Jin QW; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University, Xiamen, Fujian, China.
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Źródło:
PLoS genetics [PLoS Genet] 2022 Sep 15; Vol. 18 (9), pp. e1010397. Date of Electronic Publication: 2022 Sep 15 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Cycle Proteins*/genetics
Cell Cycle Proteins*/metabolism
Thiabendazole*/metabolism
Anaphase-Promoting Complex-Cyclosome/genetics ; Anaphase-Promoting Complex-Cyclosome/metabolism ; Cdc20 Proteins/genetics ; Cdc20 Proteins/metabolism ; Kinetochores/metabolism ; M Phase Cell Cycle Checkpoints/genetics ; Securin/genetics ; Spindle Apparatus/genetics ; Spindle Apparatus/metabolism
Czasopismo naukowe
Tytuł:
Cell Division Cycle-Associated Protein 3 (CDCA3) Is a Potential Biomarker for Clinical Prognosis and Immunotherapy in Pan-Cancer.
Autorzy:
Xu Y; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.
Shen M; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.
Peng Y; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.
Liu L; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.
Tang L; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.
Yang T; Department of Breast and Thyroid Surgery, Women and Children's Hospital of Chongqing Medical University, Chongqing 401120, China.
Pu D; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.
Tan W; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.
Zhang W; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.
Liu S; Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400042, China.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Aug 30; Vol. 2022, pp. 4632453. Date of Electronic Publication: 2022 Aug 30 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review; Retracted Publication
MeSH Terms:
Cell Cycle Proteins*/genetics
Cell Cycle Proteins*/metabolism
Neoplasms*/diagnosis
Neoplasms*/genetics
Neoplasms*/therapy
Biomarkers ; Carcinogenesis ; Cell Cycle ; Cell Proliferation ; Disease Progression ; Humans ; Immunotherapy ; Prognosis
Czasopismo naukowe
Tytuł:
MiRNA-181b-5p Modulates Cell Proliferation, Cell Cycle, and Apoptosis by Targeting SSX2IP in Acute Lymphoblastic Leukemia
Autorzy:
Fu X; Guizhou Provincial People’s Hospital, Department of Hematology, Guiyang, China
He Y; Guizhou Provincial People’s Hospital, Department of Hematology, Guiyang, China
Song J; Guizhou Provincial People’s Hospital, Department of Hematology, Guiyang, China
Wang L; Guizhou Provincial People’s Hospital, Department of Hematology, Guiyang, China
Guo P; Guizhou Provincial People’s Hospital, Department of Hematology, Guiyang, China
Cao J; Guizhou Provincial People’s Hospital, Department of Hematology, Guiyang, China
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Źródło:
Turkish journal of haematology : official journal of Turkish Society of Haematology [Turk J Haematol] 2022 Aug 25; Vol. 39 (3), pp. 160-169. Date of Electronic Publication: 2022 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Cycle Proteins*/genetics
MicroRNAs*/genetics
Microtubule-Associated Proteins*/genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma*/genetics
Animals ; Apoptosis/genetics ; Cell Cycle/genetics ; Cell Proliferation ; Humans ; Mice
Czasopismo naukowe
Tytuł:
p27 Modulates the Morphology and Phagocytic Activity of Microglia.
Autorzy:
Beeken J; UHasselt, Hasselt University, BIOMED, 3500 Hasselt, Belgium.; Laboratory of Molecular Regulation of Neurogenesis, GIGA-Stem Cells, Interdisciplinary Cluster for Applied Genoproteomics (GIGA-R), University of Liège, C.H.U. Sar-Tilman, 4000 Liège, Belgium.
Kessels S; UHasselt, Hasselt University, BIOMED, 3500 Hasselt, Belgium.
Rigo JM; UHasselt, Hasselt University, BIOMED, 3500 Hasselt, Belgium.
Alpizar YA; UHasselt, Hasselt University, BIOMED, 3500 Hasselt, Belgium.
Nguyen L; Laboratory of Molecular Regulation of Neurogenesis, GIGA-Stem Cells, Interdisciplinary Cluster for Applied Genoproteomics (GIGA-R), University of Liège, C.H.U. Sar-Tilman, 4000 Liège, Belgium.
Brône B; UHasselt, Hasselt University, BIOMED, 3500 Hasselt, Belgium.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 09; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Cycle Proteins*/metabolism
Microglia*/metabolism
Actins ; Cell Cycle/physiology ; Cyclin-Dependent Kinase Inhibitor p27/genetics ; Cyclin-Dependent Kinases/metabolism ; Cyclins/metabolism
Czasopismo naukowe

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