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Tytuł:
Perineuronal Nets in the CNS: Architects of Memory and Potential Therapeutic Target in Neuropsychiatric Disorders.
Autorzy:
Li X; National Institute on Drug Dependence, Peking University, Beijing 100191, China.; School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Wu X; Department of Laboratory Animal Sciences, Peking University Health Sciences Center, Beijing 100191, China.
Lu T; National Institute on Drug Dependence, Peking University, Beijing 100191, China.; School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Kuang C; College of Forensic Medicine, Hebei Key Laboratory of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification, Hebei Medical University, Shijiazhuang 050017, China.
Si Y; National Institute on Drug Dependence, Peking University, Beijing 100191, China.; School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Zheng W; Peking-Tsinghua Centre for Life Sciences, PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China.
Li Z; National Institute on Drug Dependence, Peking University, Beijing 100191, China.; School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Xue Y; National Institute on Drug Dependence, Peking University, Beijing 100191, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 18; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Central Nervous System*/physiology
Brain*/metabolism
Animals ; Neurons/metabolism ; Memory/physiology ; Extracellular Matrix/metabolism ; Neuronal Plasticity/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Experimental and Computational Methods to Assess Central Nervous System Penetration of Small Molecules.
Autorzy:
Gupta M; Department of Modeling and Informatics, Merck & Co., Inc., Rahway, NJ 07065, USA.
Feng J; Department of Computational Chemistry, Cellarity, 101 South Street L6, Somerville, MA 02143, USA.
Bhisetti G; Department of Computational Chemistry, Cellarity, 101 South Street L6, Somerville, MA 02143, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Mar 13; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasm Proteins*/metabolism
Brain*/metabolism
Humans ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Reproducibility of Results ; Central Nervous System/metabolism ; Blood-Brain Barrier/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Magnetic resonance imaging with upconversion nanoprobes capable of crossing the blood-cerebrospinal fluid barrier.
Autorzy:
Han F; Department of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.
Gao J; Department of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.
Lv G; Department of Materials Science and State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, P.R. China.
Liu T; Department of Oncology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.
Hu Q; Department of Urology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.
Zhu M; Department of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.
Du Z; Department of Pathology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.
Yang J; Department of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.
Yao Z; Department of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.
Fang X; Department of Medical Imaging, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu Province, 214023, P.R. China. xiangming_.
Ni D; Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, P.R. China. .
Zhang J; Department of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China. jiawen_.
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Jan 30; Vol. 22 (1), pp. 43. Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:
Journal Article
MeSH Terms:
Blood-Brain Barrier*
Brain*/diagnostic imaging
Central Nervous System ; Biological Transport/physiology ; Magnetic Resonance Imaging
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Central Nervous System Targeted Protein Degraders.
Autorzy:
Thomas BAI; Medicines Discovery Institute, Cardiff University, Cardiff CF10 3AT, UK.
Lewis HL; Medicines Discovery Institute, Cardiff University, Cardiff CF10 3AT, UK.
Jones DH; Medicines Discovery Institute, Cardiff University, Cardiff CF10 3AT, UK.; Chemistry Department, Cardiff University, Cardiff CF10 3AT, UK.
Ward SE; Medicines Discovery Institute, Cardiff University, Cardiff CF10 3AT, UK.
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Źródło:
Biomolecules [Biomolecules] 2023 Jul 25; Vol. 13 (8). Date of Electronic Publication: 2023 Jul 25.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Central Nervous System*
Brain*
Antibodies ; Amyloidogenic Proteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CLARITY increases sensitivity and specificity of fluorescence immunostaining in long-term archived human brain tissue.
Autorzy:
Woelfle S; Institute for Anatomy and Cell Biology, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.; International Graduate School in Molecular Medicine Ulm, IGradU, 89081, Ulm, Germany.
Deshpande D; Institute of Biophysics, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.; Chemical and Systems Biology Department, Stanford School of Medicine, 269 Campus Drive, Stanford, CA, 94305, USA.
Feldengut S; Clinical Neuroanatomy Section/Department of Neurology, Center for Biomedical Research, Ulm University, Helmholtzstraße 8/1, 89081, Ulm, Germany.
Braak H; Clinical Neuroanatomy Section/Department of Neurology, Center for Biomedical Research, Ulm University, Helmholtzstraße 8/1, 89081, Ulm, Germany.
Del Tredici K; Clinical Neuroanatomy Section/Department of Neurology, Center for Biomedical Research, Ulm University, Helmholtzstraße 8/1, 89081, Ulm, Germany.
Roselli F; Department of Neurology, Ulm University, 89081, Ulm, Germany.; Deutsches Zentrum für Neurodegenerative Erkrankungen, DZNE, Ulm Site, 89081, Ulm, Germany.
Deisseroth K; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, 94305, USA.; Howard Hughes Medical Institute, Stanford, CA, 94305, USA.
Michaelis J; Institute of Biophysics, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.
Boeckers TM; Institute for Anatomy and Cell Biology, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.; Deutsches Zentrum für Neurodegenerative Erkrankungen, DZNE, Ulm Site, 89081, Ulm, Germany.
Schön M; Institute for Anatomy and Cell Biology, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany. .
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Źródło:
BMC biology [BMC Biol] 2023 May 24; Vol. 21 (1), pp. 113. Date of Electronic Publication: 2023 May 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain*
Central Nervous System*
Humans ; Microscopy, Fluorescence ; Acrylamide ; Fluorescent Dyes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Gut-Liver-Brain Axis: From the Head to the Feet.
Autorzy:
Giuffrè M; Department of Internal Medicine (Digestive Diseases), Yale School of Medicine, Yale University, New Haven, CT 06510, USA.; Department of Medical, Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Moretti R; Department of Medical, Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 27; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 27.
Typ publikacji:
Editorial
MeSH Terms:
Brain*/physiology
Gastrointestinal Microbiome*/physiology
Central Nervous System/physiology ; Brain-Gut Axis ; Liver
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pathogenesis and outcome of VA1 astrovirus infection in the human brain are defined by disruption of neural functions and imbalanced host immune responses.
Autorzy:
Maximova OA; Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Weller ML; Secretory Physiology Section, Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America.
Krogmann T; Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Sturdevant DE; Research Technologies Branch, Genomics Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Ricklefs S; Research Technologies Branch, Genomics Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Virtaneva K; Research Technologies Branch, Genomics Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Martens C; Research Technologies Branch, Genomics Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America.
Wollenberg K; Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Minai M; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Moore IN; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Sauter CS; Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, United States of America.
Barker JN; Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.
Lipkin WI; Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America.
Seilhean D; Sorbonne Université, Paris, France.
Nath A; Infections of the Nervous System Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America.
Cohen JI; Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Aug 18; Vol. 19 (8), pp. e1011544. Date of Electronic Publication: 2023 Aug 18 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:
Brain*
Astroviridae Infections*
Adult ; Humans ; Central Nervous System ; Neurons ; Immunity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mechanisms of Neuroinvasion and Neuropathogenesis by Pathologic Flaviviruses.
Autorzy:
de Vries L; School of Life Sciences, Utrecht University, 3584 CS Utrecht, The Netherlands.
Harding AT; Institute for Medical Engineering and Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
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Źródło:
Viruses [Viruses] 2023 Jan 17; Vol. 15 (2). Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
Brain*
Central Nervous System*
Blood-Brain Barrier ; Apoptosis ; Axonal Transport
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel localization of folate transport systems in the murine central nervous system.
Autorzy:
Sangha V; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
Hoque MT; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
Henderson JT; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
Bendayan R; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada. .
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2022 Nov 23; Vol. 19 (1), pp. 92. Date of Electronic Publication: 2022 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Central Nervous System*
Brain*
Animals ; Mice ; Ion Transport ; Blood-Brain Barrier ; Folic Acid ; Mammals ; Proton-Coupled Folate Transporter
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Potential Mechanisms Underlying the Dysfunction of the Blood-Brain Barrier.
Autorzy:
Simpson JE; Sheffield Institute for Translational Neuroscience, The University of Sheffield, Sheffield S10 2HQ, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 03; Vol. 24 (9). Date of Electronic Publication: 2023 May 03.
Typ publikacji:
Editorial
MeSH Terms:
Blood-Brain Barrier*/physiology
Brain*
Central Nervous System ; Biological Transport ; Homeostasis
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mechanisms Controlling the Expression and Secretion of BDNF.
Autorzy:
Arévalo JC; Department of Cell Biology and Pathology, Institute of Neurosciences of Castille and Leon (INCyL), University of Salamanca, 37007 Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
Deogracias R; Department of Cell Biology and Pathology, Institute of Neurosciences of Castille and Leon (INCyL), University of Salamanca, 37007 Salamanca, Spain.; Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
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Źródło:
Biomolecules [Biomolecules] 2023 May 02; Vol. 13 (5). Date of Electronic Publication: 2023 May 02.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain-Derived Neurotrophic Factor*/genetics
Brain-Derived Neurotrophic Factor*/metabolism
Brain*/metabolism
Neuronal Plasticity/physiology ; Central Nervous System/metabolism ; Receptor, trkB/genetics ; Receptor, trkB/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CCR3 plays a role in murine age-related cognitive changes and T-cell infiltration into the brain.
Autorzy:
Rege SV; Alkahest, Inc., San Carlos, CA, USA.
Teichert A; Alkahest, Inc., San Carlos, CA, USA. .
Masumi J; Alkahest, Inc., San Carlos, CA, USA.
Dhande OS; Alkahest, Inc., San Carlos, CA, USA.
Harish R; Alkahest, Inc., San Carlos, CA, USA.
Higgins BW; Alkahest, Inc., San Carlos, CA, USA.
Lopez Y; Alkahest, Inc., San Carlos, CA, USA.
Akrapongpisak L; Alkahest, Inc., San Carlos, CA, USA.
Hackbart H; Alkahest, Inc., San Carlos, CA, USA.
Caryotakis S; Alkahest, Inc., San Carlos, CA, USA.
Leone DP; Alkahest, Inc., San Carlos, CA, USA.
Szoke B; Alkahest, Inc., San Carlos, CA, USA.
Hannestad J; Alkahest, Inc., San Carlos, CA, USA.
Nikolich K; Alkahest, Inc., San Carlos, CA, USA.
Braithwaite SP; Alkahest, Inc., San Carlos, CA, USA.
Minami SS; Alkahest, Inc., San Carlos, CA, USA.
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Źródło:
Communications biology [Commun Biol] 2023 Mar 18; Vol. 6 (1), pp. 292. Date of Electronic Publication: 2023 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
Brain*/metabolism
Receptors, CCR3*/genetics
Receptors, CCR3*/metabolism
T-Lymphocytes*/metabolism
Aging*
Animals ; Mice ; Central Nervous System ; Cognition ; Cytokines
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Untangling senescent and damage-associated microglia in the aging and diseased brain.
Autorzy:
Ng PY; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.
McNeely TL; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.
Baker DJ; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA.; Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
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Źródło:
The FEBS journal [FEBS J] 2023 Mar; Vol. 290 (5), pp. 1326-1339. Date of Electronic Publication: 2021 Dec 14.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Microglia*
Brain*
Central Nervous System ; Cellular Senescence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Brain Waste Removal System and Sleep: Photobiomodulation as an Innovative Strategy for Night Therapy of Brain Diseases.
Autorzy:
Semyachkina-Glushkovskaya O; Institute of Physics, Humboldt University, Newtonstrasse 15, 12489 Berlin, Germany.; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.
Fedosov I; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.
Penzel T; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.; Sleep Medicine Center, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Li D; Optics Valley Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China.; Advanced Biomedical Imaging Facility, School of Optical Electronic Information, Huazhong University of Science and Technology, Wuhan 430074, China.
Yu T; Optics Valley Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China.; Britton Chance Center for Biomedical Photonics, MoE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Advanced Biomedical Imaging Facility, Huazhong University of Science and Technology, Wuhan 430074, China.
Telnova V; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.
Kaybeleva E; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.
Saranceva E; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.
Terskov A; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.
Khorovodov A; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.
Blokhina I; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.
Kurths J; Institute of Physics, Humboldt University, Newtonstrasse 15, 12489 Berlin, Germany.; Department of Biology, Saratov State University, Astrakhanskaya 82, 410012 Saratov, Russia.; Potsdam Institute for Climate Impact Research, Department of Complexity Science, Telegrafenberg A31, 14473 Potsdam, Germany.
Zhu D; Optics Valley Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China.; Britton Chance Center for Biomedical Photonics, MoE Key Laboratory for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, Advanced Biomedical Imaging Facility, Huazhong University of Science and Technology, Wuhan 430074, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 06; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Brain*
Glymphatic System*
Humans ; Central Nervous System ; Sleep ; Intracranial Hemorrhages
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mechanisms of viral persistence in the brain and therapeutic approaches.
Autorzy:
Nath A; Section of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Johnson TP; Section of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.; Department of Neurology, Johns Hopkins University, Baltimore, MD, USA.
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Źródło:
The FEBS journal [FEBS J] 2022 Apr; Vol. 289 (8), pp. 2145-2161. Date of Electronic Publication: 2021 May 01.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
Brain*
Central Nervous System*
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Efficacy of Boron Neutron Capture Therapy in Primary Central Nervous System Lymphoma: In Vitro and In Vivo Evaluation.
Autorzy:
Yoshimura K; Department of Neurosurgery, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
Kawabata S; Department of Neurosurgery, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
Kashiwagi H; Department of Neurosurgery, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
Fukuo Y; Department of Neurosurgery, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
Takeuchi K; Department of Neurosurgery, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
Futamura G; Department of Neurosurgery, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
Hiramatsu R; Department of Neurosurgery, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
Takata T; Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2 Asashiro-Nishi, Kumatori-cho, Sennan 590-0494, Japan.
Tanaka H; Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2 Asashiro-Nishi, Kumatori-cho, Sennan 590-0494, Japan.
Watanabe T; Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2 Asashiro-Nishi, Kumatori-cho, Sennan 590-0494, Japan.
Suzuki M; Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2 Asashiro-Nishi, Kumatori-cho, Sennan 590-0494, Japan.
Hu N; Kansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
Miyatake SI; Kansai BNCT Medical Center, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
Wanibuchi M; Department of Neurosurgery, Osaka Medical and Pharmaceutical University, 2-7 Daigaku-Machi, Takatsuki 569-8686, Japan.
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Źródło:
Cells [Cells] 2021 Dec 02; Vol. 10 (12). Date of Electronic Publication: 2021 Dec 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Boron Neutron Capture Therapy*
Brain/*radiation effects
Central Nervous System Neoplasms/*radiotherapy
Lymphoma/*radiotherapy
Animals ; Apoptosis/radiation effects ; Boron/chemistry ; Boron/isolation & purification ; Boron/pharmacology ; Brain/pathology ; Cell Line, Tumor ; Cell Survival/drug effects ; Central Nervous System Neoplasms/drug therapy ; Central Nervous System Neoplasms/pathology ; Cranial Irradiation ; Disease Models, Animal ; Humans ; Lymphoma/drug therapy ; Lymphoma/pathology ; Methotrexate/pharmacology ; Mice ; Phenylalanine/chemistry ; Phenylalanine/isolation & purification ; Phenylalanine/pharmacology ; Tissue Distribution/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microarray profiling predicts early neurological and immune phenotypic traits in advance of CNS disease during disease progression in Trypanosoma. b. brucei infected CD1 mouse brains.
Autorzy:
Montague P; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, Glasgow, United Kingdom.
Bradley B; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, Glasgow, United Kingdom.
Rodgers J; Institute of Biodiversity, Animal Health and Comparative Medicine, Glasgow, United Kingdom.
Kennedy PGE; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, Glasgow, United Kingdom.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Nov 11; Vol. 15 (11), pp. e0009892. Date of Electronic Publication: 2021 Nov 11 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain/*parasitology
Central Nervous System Diseases/*genetics
Central Nervous System Diseases/*immunology
Trypanosoma brucei brucei/*physiology
Trypanosomiasis, African/*genetics
Trypanosomiasis, African/*immunology
Animals ; Blood-Brain Barrier/immunology ; Blood-Brain Barrier/parasitology ; Brain/immunology ; Central Nervous System Diseases/parasitology ; Disease Models, Animal ; Disease Progression ; Female ; Gene Expression Profiling ; Humans ; Mice ; Phenotype ; Protein Array Analysis ; Transcription, Genetic ; Trypanosomiasis, African/parasitology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A non-invasive direct nose to brain drug delivery platform vs. invasive brain delivery approach: patient-centered care impact analysis.
Autorzy:
Kobo-Greenhut A; Risk Management, Validation, Regulation, Haifa, Israel.; Zefat Academic College, Zefet, Israel.
Frankenthal H; Zefat Academic College, Zefet, Israel.
Darawsha A; Emergency Department, Rambam Medical Center, Haifa, Israel.
Karasik A; Sheba Medical Center, Tel HaShomer, Israel.
Zohar Beja A
Ben Hur T; Department of Neurology, Hadassah Medical Center, Jerusalem, Israel.
Ekstien D; Department of Neurology, Hadassah Medical Center, Jerusalem, Israel.
Amir L; Department of Emergency Medicine, Schneider Medical Center, Petakh Tikva, Israel.
Shahaf D; SipNose LTD, Yokne'am Illit, Israel.
Ben Shlomo I; Zefat Academic College, Zefet, Israel.
Shichor I; SipNose LTD, Yokne'am Illit, Israel.
Frey WH; Center for Memory & Aging, Center for Memory & Aging HealthPartners Neuroscience Center, St Paul, MN, USA.
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Źródło:
Drug delivery [Drug Deliv] 2022 Dec; Vol. 29 (1), pp. 1754-1763.
Typ publikacji:
Journal Article
MeSH Terms:
Brain*
Drug Delivery Systems*
Central Nervous System Agents ; Humans ; Patient-Centered Care
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
microRNA-146a-5p, Neurotropic Viral Infection and Prion Disease (PrD).
Autorzy:
Pogue AI; Alchem Biotech, Toronto, ON M5S 1A8, Canada.
Lukiw WJ; LSU Neuroscience Center, Louisiana State University Health Science Center, New Orleans, LA 70112, USA.; Department of Ophthalmology, Louisiana State University Health Science Center, New Orleans, LA 70112, USA.; Department of Neurology, Louisiana State University Health Science Center, New Orleans, LA 70112, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 25; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Brain/*pathology
Central Nervous System Viral Diseases/*immunology
Gene Expression Regulation/*immunology
MicroRNAs/*metabolism
Prion Diseases/*immunology
Apoptosis/genetics ; Apoptosis/immunology ; Biomarkers/analysis ; Biomarkers/metabolism ; Brain/immunology ; Brain/virology ; Central Nervous System Viral Diseases/diagnosis ; Central Nervous System Viral Diseases/genetics ; Central Nervous System Viral Diseases/virology ; Complement Factor H/metabolism ; Cytokines/metabolism ; Humans ; MicroRNAs/analysis ; MicroRNAs/genetics ; NF-kappa B/metabolism ; Prion Diseases/diagnosis ; Prion Diseases/genetics ; Prion Diseases/pathology ; Signal Transduction/genetics ; Signal Transduction/immunology ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Gut-Brain Axis in Inflammatory Bowel Disease-Current and Future Perspectives.
Autorzy:
Günther C; Department of Medicine 1, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Rothhammer V; Department of Neurology, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Karow M; Institute of Biochemistry, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Neurath M; Department of Medicine 1, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Winner B; Department of Stem Cell Biology, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 18; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 18.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Brain/*pathology
Central Nervous System Diseases/*pathology
Inflammatory Bowel Diseases/*complications
Animals ; Brain/metabolism ; Central Nervous System Diseases/etiology ; Central Nervous System Diseases/metabolism ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 11350

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