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Tytuł :
The Centromere Histone Is Conserved and Associated with Tandem Repeats Sharing a Conserved 19-bp Box in the Holocentromere of Meloidogyne Nematodes.
Autorzy :
Despot-Slade E; Ruđer Bošković Institute, Zagreb, Croatia.
Mravinac B; Ruđer Bošković Institute, Zagreb, Croatia.
Širca S; Agricultural Institute Slovenia, Ljubljana, Slovenia.
Castagnone-Sereno P; INRAE, Université Côte d'Azur, CNRS, Sophia Antipolis, France.
Plohl M; Ruđer Bošković Institute, Zagreb, Croatia.
Meštrović N; Ruđer Bošković Institute, Zagreb, Croatia.
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Źródło :
Molecular biology and evolution [Mol Biol Evol] 2021 May 04; Vol. 38 (5), pp. 1943-1965.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Centromere*
Histones/*genetics
Tylenchoidea/*genetics
Animals ; Centromere Protein A/genetics ; Chromatin Immunoprecipitation Sequencing ; Conserved Sequence ; Evolution, Molecular ; Tandem Repeat Sequences
Czasopismo naukowe
Tytuł :
Truly epigenetic: A centromere finds a "neo" home.
Autorzy :
Carty BL; Centre for Chromosome Biology, Biomedical Sciences, National University of Ireland Galway, Galway, Ireland.
Dunleavy EM; Centre for Chromosome Biology, Biomedical Sciences, National University of Ireland Galway, Galway, Ireland.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Mar 01; Vol. 220 (3).
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Centromere*/genetics
Epigenomics*
Centromere Protein A/genetics ; Epigenesis, Genetic ; Humans
Czasopismo naukowe
Tytuł :
CENP-A nucleosome-a chromatin-embedded pedestal for the centromere: lessons learned from structural biology.
Autorzy :
Ali-Ahmad A; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, Faculty of Medicine, University of Oslo, Oslo 0318, Norway.
Sekulić N; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, Faculty of Medicine, University of Oslo, Oslo 0318, Norway.; Department of Chemistry, University of Oslo, P.O. Box 1033, Blindern NO-0315, Norway.
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Źródło :
Essays in biochemistry [Essays Biochem] 2020 Sep 04; Vol. 64 (2), pp. 205-221.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Centromere Protein A*/chemistry
Centromere Protein A*/physiology
Nucleosomes/*chemistry
Centromere/chemistry ; Chromatin/chemistry ; Humans ; Molecular Conformation ; Saccharomyces cerevisiae
Czasopismo naukowe
Tytuł :
Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Autorzy :
Guan R; Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Lian T; Laboratory of Membrane Proteins and Structural Biology, Biochemistry and Biophysics Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Zhou BR; Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
He E; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
Wu C; Department of Biology, Johns Hopkins University, Baltimore, MD, USA.
Singleton M; Structural Biology of Chromosome Segregation Laboratory, The Francis Crick Institute, London, UK.
Bai Y; Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Mar 19; Vol. 12 (1), pp. 1763. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Centromere/*metabolism
DNA, Fungal/*metabolism
DNA-Binding Proteins/*metabolism
Kinetochores/*metabolism
Nucleosomes/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Amino Acid Sequence ; Centromere/genetics ; Centromere/ultrastructure ; Centromere Protein A/chemistry ; Centromere Protein A/genetics ; Centromere Protein A/metabolism ; Cryoelectron Microscopy ; DNA, Fungal/chemistry ; DNA, Fungal/genetics ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; Histones/chemistry ; Histones/genetics ; Histones/metabolism ; Humans ; Kinetochores/chemistry ; Nucleic Acid Conformation ; Nucleosomes/genetics ; Nucleosomes/ultrastructure ; Protein Binding ; Protein Domains ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
Induction of spontaneous human neocentromere formation and long-term maturation.
Autorzy :
Murillo-Pineda M; Department of Biochemistry, University of Oxford, Oxford, UK.; Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Valente LP; Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Dumont M; Institut Curie, Paris Sciences et Lettres, Research University, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 144, Paris, France.
Mata JF; Instituto Gulbenkian de Ciência, Oeiras, Portugal.
Fachinetti D; Institut Curie, Paris Sciences et Lettres, Research University, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 144, Paris, France.
Jansen LET; Department of Biochemistry, University of Oxford, Oxford, UK.; Instituto Gulbenkian de Ciência, Oeiras, Portugal.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Mar 01; Vol. 220 (3).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Centromere/*metabolism
Base Pairing/genetics ; Cell Cycle Proteins/metabolism ; Cell Line ; Centromere Protein A/chemistry ; Centromere Protein A/metabolism ; Chromatin/metabolism ; Chromosomal Proteins, Non-Histone/metabolism ; Epigenesis, Genetic ; Genome, Human ; Histones/metabolism ; Humans ; Kinetochores/metabolism ; Methylation ; Protein Domains ; RNA Polymerase II/metabolism ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Ancient Coretention of Paralogs of Cid Centromeric Histones and Cal1 Chaperones in Mosquito Species.
Autorzy :
Kursel LE; Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, WA.; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA.; Department of Biology, University of Utah, Salt Lake City, UT.
Welsh FC; Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, WA.; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA.; University of Puget Sound, Tacoma, WA.
Malik HS; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA.; Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, WA.
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Źródło :
Molecular biology and evolution [Mol Biol Evol] 2020 Jul 01; Vol. 37 (7), pp. 1949-1963.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Centromere*
Genome, Insect*
Culicidae/*genetics
Insect Proteins/*genetics
Animals ; Centromere Protein A/genetics ; Drosophila Proteins/genetics
Czasopismo naukowe
Tytuł :
Targeted De Novo Centromere Formation in Drosophila Reveals Plasticity and Maintenance Potential of CENP-A Chromatin.
Autorzy :
Palladino J; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA.
Chavan A; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA.
Sposato A; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA.
Mason TD; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA.
Mellone BG; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA; Institute for Systems Genomics, University of Connecticut, Storrs, CT 06269, USA. Electronic address: .
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Źródło :
Developmental cell [Dev Cell] 2020 Feb 10; Vol. 52 (3), pp. 379-394.e7.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cell Plasticity*
Centromere*
Epigenesis, Genetic*
Centromere Protein A/*metabolism
Chromatin/*metabolism
Drosophila Proteins/*metabolism
Drosophila melanogaster/*metabolism
Histones/*metabolism
Animals ; Centromere Protein A/genetics ; Chromatin/genetics ; Chromosome Segregation ; Drosophila Proteins/genetics ; Drosophila melanogaster/genetics ; Drosophila melanogaster/growth & development ; Female ; Histones/genetics ; Male
Czasopismo naukowe
Tytuł :
Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A.
Autorzy :
Wang X; Department of Biochemistry & Molecular Biology, Harbin Medical University, Harbin, China; Department of Cell Biology & Anatomy, Arnie Charbonneau Cancer and Alberta Children's Hospital Research Institutes, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Rosales JL; Department of Cell Biology & Anatomy, Arnie Charbonneau Cancer and Alberta Children's Hospital Research Institutes, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Gao X; Department of Biochemistry & Molecular Biology, Harbin Medical University, Harbin, China. Electronic address: .
Lee KY; Department of Cell Biology & Anatomy, Arnie Charbonneau Cancer and Alberta Children's Hospital Research Institutes, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jun; Vol. 138, pp. 111463. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Cycle Proteins/*deficiency
Centromere/*metabolism
Centromere Protein A/*metabolism
Chromatin/*metabolism
Nerve Tissue Proteins/*deficiency
Transcriptional Activation/*physiology
Cell Cycle Proteins/genetics ; Cell Line, Transformed ; Cell Line, Tumor ; Centromere/genetics ; Centromere Protein A/genetics ; Chromatin/genetics ; Chromosome Segregation/physiology ; HEK293 Cells ; Humans ; Male ; Nerve Tissue Proteins/genetics ; Nucleosomes/genetics ; Nucleosomes/metabolism
Czasopismo naukowe
Tytuł :
Centromeres under Pressure: Evolutionary Innovation in Conflict with Conserved Function.
Autorzy :
Balzano E; Dipartimento di Biologia e Biotecnologie 'Charles Darwin', Sapienza Università di Roma, 00185 Roma, Italy.
Giunta S; Laboratory of Chromosome and Cell Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.
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Źródło :
Genes [Genes (Basel)] 2020 Aug 10; Vol. 11 (8). Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Evolution, Molecular*
Gene Expression Regulation*
Centromere/*genetics
Animals ; Centromere Protein A/chemistry ; Centromere Protein A/genetics ; Chromosome Mapping ; Conserved Sequence ; Genetic Variation ; Genomic Instability ; Humans ; Mutagenesis ; Repetitive Sequences, Nucleic Acid ; Species Specificity
Czasopismo naukowe
Tytuł :
Reprogramming of human cells to pluripotency induces CENP-A chromatin depletion.
Autorzy :
Milagre I; Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 6, 2780-156 Oeiras, Portugal.
Pereira C; Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 6, 2780-156 Oeiras, Portugal.
Oliveira RA; Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 6, 2780-156 Oeiras, Portugal.
Jansen LET; Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 6, 2780-156 Oeiras, Portugal.; Department of Biochemistry, University of Oxford, OX1, 3QU, UK.
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Źródło :
Open biology [Open Biol] 2020 Oct; Vol. 10 (10), pp. 200227. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cellular Reprogramming/*genetics
Centromere Protein A/*metabolism
Chromatin/*genetics
Pluripotent Stem Cells/*metabolism
Cell Cycle/genetics ; Cell Differentiation/genetics ; Cell Line ; Centromere/genetics ; Centromere/metabolism ; Chromatin/metabolism ; Fibroblasts/metabolism ; Humans ; Kinetochores/metabolism ; Mitosis/genetics ; Models, Biological ; Pluripotent Stem Cells/cytology
Czasopismo naukowe
Tytuł :
Centromeric Transcription: A Conserved Swiss-Army Knife.
Autorzy :
Arunkumar G; Chromatin Structure and Epigenetic Mechanisms, Laboratory of Receptor Biology and Gene Expression, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
Melters DP; Chromatin Structure and Epigenetic Mechanisms, Laboratory of Receptor Biology and Gene Expression, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.
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Źródło :
Genes [Genes (Basel)] 2020 Aug 09; Vol. 11 (8). Date of Electronic Publication: 2020 Aug 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms :
Transcription, Genetic*
Centromere/*genetics
Animals ; Centromere Protein B/metabolism ; Chromatin/genetics ; Chromatin Assembly and Disassembly ; Evolution, Molecular ; Gene Expression Regulation ; Humans ; RNA Processing, Post-Transcriptional ; RNA, Long Noncoding ; RNA, Small Untranslated ; Repetitive Sequences, Nucleic Acid
Czasopismo naukowe
Tytuł :
Epigenetic regulation of centromere function.
Autorzy :
Wong CYY; School of Biological Sciences, The University of Hong Kong, Kadoorie Biological Sciences Building, Pokfulam Road, Hong Kong, China.
Lee BCH; School of Biological Sciences, The University of Hong Kong, Kadoorie Biological Sciences Building, Pokfulam Road, Hong Kong, China.
Yuen KWY; School of Biological Sciences, The University of Hong Kong, Kadoorie Biological Sciences Building, Pokfulam Road, Hong Kong, China. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Aug; Vol. 77 (15), pp. 2899-2917. Date of Electronic Publication: 2020 Feb 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Epigenesis, Genetic*
Centromere/*metabolism
Centromere Protein A/metabolism ; Heterochromatin/chemistry ; Heterochromatin/metabolism ; Histones/metabolism ; Humans ; Protein Processing, Post-Translational ; RNA Interference
Czasopismo naukowe
Tytuł :
The Elusive Structure of Centro-Chromatin: Molecular Order or Dynamic Heterogenetity?
Autorzy :
Nagpal H; Laboratory of Biophysical Chemistry of Macromolecules, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address: .
Fierz B; Laboratory of Biophysical Chemistry of Macromolecules, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Mar 19; Vol. 433 (6), pp. 166676. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Centromere/*ultrastructure
Centromere Protein A/*chemistry
Centromere Protein B/*chemistry
Chromatin/*ultrastructure
Chromosomal Proteins, Non-Histone/*chemistry
Adenosine Triphosphatases/chemistry ; Adenosine Triphosphatases/genetics ; Adenosine Triphosphatases/metabolism ; Cell Cycle Proteins/chemistry ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Centromere/chemistry ; Centromere/metabolism ; Centromere Protein A/genetics ; Centromere Protein A/metabolism ; Centromere Protein B/genetics ; Centromere Protein B/metabolism ; Chromatin/chemistry ; Chromatin/metabolism ; Chromosomal Proteins, Non-Histone/genetics ; Chromosomal Proteins, Non-Histone/metabolism ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Epigenesis, Genetic ; Humans ; Mitosis ; Models, Molecular ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/genetics ; Multiprotein Complexes/metabolism ; Nucleic Acid Conformation ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
CENP-A chromatin prevents replication stress at centromeres to avoid structural aneuploidy.
Autorzy :
Giunta S; Laboratory of Chromosome and Cell Biology, The Rockefeller University, New York, NY 10065; .
Hervé S; Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France.
White RR; Laboratory of Genome Maintenance, The Rockefeller University, New York, NY 10065.
Wilhelm T; Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France.
Dumont M; Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France.
Scelfo A; Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France.
Gamba R; Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France.
Wong CK; Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), 138648 Singapore, Singapore.
Rancati G; Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), 138648 Singapore, Singapore.
Smogorzewska A; Laboratory of Genome Maintenance, The Rockefeller University, New York, NY 10065.
Funabiki H; Laboratory of Chromosome and Cell Biology, The Rockefeller University, New York, NY 10065; .
Fachinetti D; Institut Curie, PSL Research University, CNRS, UMR 144, F-75005 Paris, France; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Mar 09; Vol. 118 (10).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Aneuploidy*
DNA Replication*
Centromere/*metabolism
Centromere Protein A/*metabolism
Chromatin/*metabolism
Chromosomes, Human/*metabolism
Cell Line ; Centromere/genetics ; Centromere Protein A/genetics ; Chromatin/genetics ; Chromosomes, Human/genetics ; Humans ; S Phase
Czasopismo naukowe
Tytuł :
Alpha satellite DNA-repeat OwlAlp1 forms centromeres in Azara's owl monkey.
Autorzy :
Oizumi Y; Institute for Protein Research, Osaka University, Suita, Japan.
Koga A; Primate Research Institute, Kyoto University, Inuyama, Japan.
Kanoh J; Institute for Protein Research, Osaka University, Suita, Japan.
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Źródło :
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2019 Jul; Vol. 24 (7), pp. 511-517. Date of Electronic Publication: 2019 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Centromere*
DNA, Satellite*
Heterochromatin*
Aotidae/*genetics
Centromere Protein A/*metabolism
Animals ; Cells, Cultured ; Centromere Protein A/genetics ; Centromere Protein A/immunology ; Chromatin Immunoprecipitation ; Histones/genetics ; Humans
Czasopismo naukowe
Tytuł :
CentromereArchitect: inference and analysis of the architecture of centromeres.
Autorzy :
Dvorkina T; Center for Algorithmic Biotechnology, Institute of Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
Kunyavskaya O; Center for Algorithmic Biotechnology, Institute of Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
Bzikadze AV; Graduate Program in Bioinformatics and Systems Biology, University of California, San Diego, CA 92093, USA.
Alexandrov I; Center for Algorithmic Biotechnology, Institute of Translational Biomedicine, Saint Petersburg State University, Saint Petersburg 199034, Russia.
Pevzner PA; Department of Computer Science and Engineering, University of California, San Diego, CA 92093, USA.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2021 Jul 12; Vol. 37 (Suppl_1), pp. i196-i204.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Centromere*/genetics
Genome*
Algorithms ; Base Sequence ; Humans ; Telomere
Czasopismo naukowe
Tytuł :
Molecular Complexes at Euchromatin, Heterochromatin and Centromeric Chromatin.
Autorzy :
Morrison O; Department of Biology, Emory University, 1510 Clifton Rd #2006, Atlanta, GA 30322, USA.
Thakur J; Department of Biology, Emory University, 1510 Clifton Rd #2006, Atlanta, GA 30322, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 28; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Centromere/*metabolism
Euchromatin/*metabolism
Heterochromatin/*metabolism
Animals ; Centromere/genetics ; Chromatin/genetics ; Chromatin/metabolism ; Epigenesis, Genetic/genetics ; Euchromatin/genetics ; Heterochromatin/genetics ; Humans
Czasopismo naukowe
Tytuł :
Stable inheritance of CENP-A chromatin: Inner strength versus dynamic control.
Autorzy :
Mitra S; Department of Biochemistry, University of Oxford, Oxford, UK.
Srinivasan B; Mechanistic Biology and Profiling, Discovery Sciences, R&D, AstraZeneca, Cambridge, UK.
Jansen LET; Department of Biochemistry, University of Oxford, Oxford, UK.
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Źródło :
The Journal of cell biology [J Cell Biol] 2020 Oct 05; Vol. 219 (10).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Centromere Protein A/*genetics
Chromosome Segregation/*genetics
DNA Replication/*genetics
Epigenesis, Genetic/*genetics
Autoantigens/genetics ; Centromere/genetics ; Chromatin/genetics ; Chromosomal Proteins, Non-Histone/genetics ; DNA-Binding Proteins/genetics ; HeLa Cells ; Histones/genetics ; Humans ; Nucleosomes/genetics ; Spindle Apparatus/genetics
Czasopismo naukowe
Tytuł :
Automated classification of mitotic catastrophe by use of the centromere fragmentation morphology.
Autorzy :
Roy K; Department of Oncology, University of Alberta, Edmonton, AB T6G 1Z2, Canada.; Experimental Oncology, Cross Cancer Institute, Edmonton, AB T6G 1Z2, Canada.; Cancer Research Institute of Northern Alberta, University of Alberta, Edmonton, AB T6G 2J7, Canada.; Department of Computer Science and Engineering, Jadavpur University, 188 Raja S.C. Mallick Road, Kolkata, WB, India 700032.
Lewis CW; Department of Oncology, University of Alberta, Edmonton, AB T6G 1Z2, Canada.; Experimental Oncology, Cross Cancer Institute, Edmonton, AB T6G 1Z2, Canada.; Cancer Research Institute of Northern Alberta, University of Alberta, Edmonton, AB T6G 2J7, Canada.
Chan GK; Department of Oncology, University of Alberta, Edmonton, AB T6G 1Z2, Canada.; Experimental Oncology, Cross Cancer Institute, Edmonton, AB T6G 1Z2, Canada.; Cancer Research Institute of Northern Alberta, University of Alberta, Edmonton, AB T6G 2J7, Canada.
Bhattacharjee D; Department of Computer Science and Engineering, Jadavpur University, 188 Raja S.C. Mallick Road, Kolkata, WB, India 700032.
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Źródło :
Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2021 Apr; Vol. 99 (2), pp. 261-271. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Automation*
Centromere/*genetics
Mitosis/*genetics
Algorithms ; Centromere/metabolism ; Centromere/pathology ; HeLa Cells ; Humans ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Guarding the Genome: CENP-A-Chromatin in Health and Cancer.
Autorzy :
Mahlke MA; UPMC Hillman Cancer Center, Pittsburgh, PA 15213, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Nechemia-Arbely Y; UPMC Hillman Cancer Center, Pittsburgh, PA 15213, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
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Źródło :
Genes [Genes (Basel)] 2020 Jul 16; Vol. 11 (7). Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Health*
Centromere Protein A/*physiology
Chromatin/*physiology
Genomic Instability/*physiology
Neoplasms/*genetics
Animals ; Centromere/metabolism ; Chromatin/metabolism ; Chromosomal Instability/genetics ; Chromosome Segregation/physiology ; Epigenesis, Genetic/physiology ; Humans ; Neoplasms/metabolism ; Neoplasms/pathology
Czasopismo naukowe

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