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Tytuł:
Enthesis: not the same in each localisation – a molecular, histological and biomechanical study
Autorzy:
CJ Peniche Silva
SA Müller
N Quirk
RE De la Vega
MJ Coenen
CH Evans
ER Balmayor
M van Griensven
Pokaż więcej
Temat:
enthesis
patellar tendon
achilles tendon
supraspinatus
Surgery
RD1-811
Diseases of the musculoskeletal system
RC925-935
Źródło:
European Cells & Materials, Vol 44, Pp 43-55 (2022)
Opis pliku:
electronic resource
Relacje:
https://www.ecmjournal.org/papers/vol044/pdf/v044a03.pdf; https://doaj.org/toc/1473-2262
Dostęp URL:
https://doaj.org/article/2da97e09d94d4b1fad71d50c4618a74a  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1
Autorzy:
T-Y Liu
M Bartnikowski
AC Wu
M Veitch
KA Sokolowski
SM Millard
AR Pettit
V Glatt
CH Evans
JW Wells
Pokaż więcej
Temat:
tacrolimus
fk506
bone healing
immunosuppression
local administration
mouse
Surgery
RD1-811
Diseases of the musculoskeletal system
RC925-935
Źródło:
European Cells & Materials, Vol 41, Pp 345-354 (2021)
Opis pliku:
electronic resource
Relacje:
https://www.ecmjournal.org/papers/vol041/pdf/v041a22.pdf; https://doaj.org/toc/1473-2262
Dostęp URL:
https://doaj.org/article/350f73564bb14ea8b5484ab025e30d00  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Effects of FK506 on the healing of diaphyseal, critical size defects in the rat femur
Autorzy:
RE De la Vega
MJ Coenen
SA Müller
CV Nagelli
NP Quirk
C Lopez de Padilla
CH Evans
Pokaż więcej
Temat:
immunosuppression
bone healing
gene therapy
adenovirus
rat
bmp-2.
Surgery
RD1-811
Diseases of the musculoskeletal system
RC925-935
Źródło:
European Cells & Materials, Vol 40, Pp 160-171 (2020)
Opis pliku:
electronic resource
Relacje:
https://www.ecmjournal.org/papers/vol040/pdf/v040a10.pdf; https://doaj.org/toc/1473-2262
Dostęp URL:
https://doaj.org/article/b0f649660b554ceba5f07e254fc65794  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Paracrine effects of living human bone particles on the osteogenic differentiation of mesenchymal stem cells
Autorzy:
A Atasoy-Zeybek
A Ivkovic
T Beyzadeoglu
A Ona
CH Evans
GT Kose
Pokaż więcej
Temat:
Autograft
bone chips
osteogenesis
mesenchymal stem cell
fracture healing.
Surgery
RD1-811
Diseases of the musculoskeletal system
RC925-935
Źródło:
European Cells & Materials, Vol 38, Pp 14-22 (2019)
Opis pliku:
electronic resource
Relacje:
http://www.ecmjournal.org/papers/vol038/pdf/v038a02.pdf; https://doaj.org/toc/1473-2262
Dostęp URL:
https://doaj.org/article/24e495b740214da08456cb6bd2741adb  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Design, characterisation and in vivo testing of a new, adjustable stiffness, external fixator for the rat femur
Autorzy:
V Glatt
CH Evans
R Matthys
Pokaż więcej
Temat:
External fixator
bone healing
small animal model
mechanical stiffness
mechanobiology
dynamisation
Surgery
RD1-811
Diseases of the musculoskeletal system
RC925-935
Źródło:
European Cells & Materials, Vol 23, Pp 289-299 (2012)
Opis pliku:
electronic resource
Relacje:
http://www.ecmjournal.org/journal/papers/vol023/pdf/v023a22.pdf; https://doaj.org/toc/1473-2262
Dostęp URL:
https://doaj.org/article/3be9ffce621b44268b999a71b4454dbc  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
MiRNAs as Potential Regulators of Enthesis Healing: Findings in a Rodent Injury Model.
Autorzy:
Peniche Silva CJ; Cell Biology-Inspired Tissue Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands.
De La Vega RE; Cell Biology-Inspired Tissue Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands.; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.
Panos J; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.
Joris V; Cell Biology-Inspired Tissue Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands.
Evans CH; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.
Balmayor ER; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.; Experimental Orthopaedics and Trauma Surgery, Department of Orthopaedic, Trauma, and Reconstructive Surgery, RWTH Aachen University Hospital, 52074 Aachen, Germany.
van Griensven M; Cell Biology-Inspired Tissue Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands.; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 10; Vol. 24 (10). Date of Electronic Publication: 2023 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/metabolism
Rats ; Animals ; Rodentia/metabolism ; Wound Healing/genetics ; Patella ; RNA, Messenger/metabolism ; Gene Expression Profiling
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enthesis Healing Is Dependent on Scaffold Interphase Morphology-Results from a Rodent Patellar Model.
Autorzy:
Peniche Silva CJ; cBITE, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands.
Müller SA; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.; Department of Orthopedic Surgery, University of Basel, P.O. Box 4001 Basel, Switzerland.
Quirk N; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.
Poh PSP; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Julius Wolff Institute, 13353 Berlin, Germany.
Mayer C; Department of General, Visceral and Minimally Invasive Surgery and Endoscopy, Dr. Lubos Kliniken Bogenhausen, 81679 Munich, Germany.
Motta A; BIOtech Research Center and European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Department of Industrial Engineering, University of Trento, 38123 Trento, Italy.
Migliaresi C; BIOtech Research Center and European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Department of Industrial Engineering, University of Trento, 38123 Trento, Italy.
Coenen MJ; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.
Evans CH; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.
Balmayor ER; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.; Department of Orthopaedic, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, 52074 Aachen, Germany.
van Griensven M; cBITE, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, 6229 ER Maastricht, The Netherlands.; Musculoskeletal Gene Therapy Laboratory, Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN 55905, USA.
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Źródło:
Cells [Cells] 2022 May 26; Vol. 11 (11). Date of Electronic Publication: 2022 May 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fibroins*/pharmacology
Tendon Injuries*
Tissue Scaffolds*
Wound Healing*
Animals ; Interphase ; Rats ; Tendons
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Different types of cartilage neotissue fabricated from collagen hydrogels and mesenchymal stromal cells via SOX9, TGFB1 or BMP2 gene transfer.
Autorzy:
Weißenberger M; Department of Orthopaedic Surgery, König-Ludwig-Haus, Orthopaedic Center for Musculoskeletal Research (OCMR), Julius-Maximilians-University Würzburg, Würzburg, Germany.
Weißenberger MH; Department of Orthopaedic Surgery, König-Ludwig-Haus, Orthopaedic Center for Musculoskeletal Research (OCMR), Julius-Maximilians-University Würzburg, Würzburg, Germany.
Wagenbrenner M; Department of Orthopaedic Surgery, König-Ludwig-Haus, Orthopaedic Center for Musculoskeletal Research (OCMR), Julius-Maximilians-University Würzburg, Würzburg, Germany.
Heinz T; Department of Orthopaedic Surgery, König-Ludwig-Haus, Orthopaedic Center for Musculoskeletal Research (OCMR), Julius-Maximilians-University Würzburg, Würzburg, Germany.
Reboredo J; Department of Tissue Engineering and Regenerative Medicine, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Holzapfel BM; Department of Orthopaedic Surgery, König-Ludwig-Haus, Orthopaedic Center for Musculoskeletal Research (OCMR), Julius-Maximilians-University Würzburg, Würzburg, Germany.
Rudert M; Department of Orthopaedic Surgery, König-Ludwig-Haus, Orthopaedic Center for Musculoskeletal Research (OCMR), Julius-Maximilians-University Würzburg, Würzburg, Germany.
Groll J; Department of Functional Materials in Medicine and Dentistry, Julius-Maximilians-University Würzburg, Würzburg, Germany.
Evans CH; Department of Physical Medicine and Rehabilitation, Musculoskeletal Gene Therapy Research Laboratory, Mayo Clinic, Rochester, MN, United States of America.
Steinert AF; Department of Orthopaedic Surgery, König-Ludwig-Haus, Orthopaedic Center for Musculoskeletal Research (OCMR), Julius-Maximilians-University Würzburg, Würzburg, Germany.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2020 Aug 13; Vol. 15 (8), pp. e0237479. Date of Electronic Publication: 2020 Aug 13 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone Morphogenetic Protein 2/*genetics
Hydrogels/*chemistry
SOX9 Transcription Factor/*genetics
Transforming Growth Factor beta1/*genetics
Alkaline Phosphatase/genetics ; Alkaline Phosphatase/metabolism ; Bone Morphogenetic Protein 2/metabolism ; Cartilage/cytology ; Cartilage/metabolism ; Cartilage/pathology ; Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Chondrogenesis/genetics ; Collagen Type I/chemistry ; Collagen Type X/genetics ; Culture Media, Serum-Free/chemistry ; Glycosaminoglycans/metabolism ; Humans ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/metabolism ; Osteoarthritis/metabolism ; Osteoarthritis/pathology ; RNA, Messenger/metabolism ; SOX9 Transcription Factor/metabolism ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Reduced hypertrophy in vitro after chondrogenic differentiation of adult human mesenchymal stem cells following adenoviral SOX9 gene delivery.
Autorzy:
Weissenberger M; Department of Orthopaedic Surgery, König-Ludwig-Haus, Center for Musculoskeletal Research, Julius-Maximilians-University, Brettreichstrasse 11, D-97074, Würzburg, Germany. .
Weissenberger MH; Department of Orthopaedic Surgery, König-Ludwig-Haus, Center for Musculoskeletal Research, Julius-Maximilians-University, Brettreichstrasse 11, D-97074, Würzburg, Germany.; Department of Pathology, Caritas-Hospital, Bad Mergentheim, Germany.
Gilbert F; Department of Orthopaedic Surgery, König-Ludwig-Haus, Center for Musculoskeletal Research, Julius-Maximilians-University, Brettreichstrasse 11, D-97074, Würzburg, Germany.; Department of Orthopaedic Trauma, Hand, Plastic and Reconstructive Surgery, University Hospital Würzburg, Würzburg, Germany.
Groll J; Department of Functional Materials in Medicine and Dentistry, Julius-Maximilians-University, Würzburg, Germany.
Evans CH; Rehabilitation Medicine Research Center, Mayo Clinic, Rochester, MN, USA.
Steinert AF; Department of Orthopaedic Surgery, König-Ludwig-Haus, Center for Musculoskeletal Research, Julius-Maximilians-University, Brettreichstrasse 11, D-97074, Würzburg, Germany.; Present address: Department of Orthopaedic, Trauma, Shoulder and Arthroplasty Surgery, Rhön-Klinikum Campus Bad Neustadt, Bad Neustadt a.d. Saale, Germany.
Pokaż więcej
Źródło:
BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2020 Feb 17; Vol. 21 (1), pp. 109. Date of Electronic Publication: 2020 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Transfer Techniques*
Adenoviridae/*genetics
Cell Differentiation/*physiology
Chondrogenesis/*physiology
Mesenchymal Stem Cells/*physiology
SOX9 Transcription Factor/*genetics
Adult ; Aged ; Cells, Cultured ; Female ; Humans ; Hypertrophy ; Male ; Middle Aged ; SOX9 Transcription Factor/biosynthesis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preclinical toxicity evaluation of AAV for pain: evidence from human AAV studies and from the pharmacology of analgesic drugs.
Autorzy:
Pleticha J
Heilmann LF
Evans CH
Asokan A
Samulski RJ
Beutler AS; Departments of Anesthesiology, Oncology, and the Cancer Center, Mayo Clinic, Rochester, MN, USA. .
Pokaż więcej
Źródło:
Molecular pain [Mol Pain] 2014 Sep 02; Vol. 10, pp. 54. Date of Electronic Publication: 2014 Sep 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Drug Evaluation, Preclinical*
Genetic Therapy*
Pain Management*
Analgesics/*therapeutic use
Pain/*drug therapy
Animals ; Genetic Vectors/metabolism ; Humans ; Pain/genetics ; Satellite Viruses/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
TNFα and IL-1β influence the differentiation and migration of murine MSCs independently of the NF-κB pathway.
Autorzy:
Sullivan CB
Porter RM
Evans CH
Ritter T
Shaw G
Barry F
Murphy JM
Pokaż więcej
Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2014 Aug 27; Vol. 5 (4), pp. 104. Date of Electronic Publication: 2014 Aug 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation/*genetics
Cell Movement/*genetics
Interleukin-1beta/*pharmacology
Mesenchymal Stem Cells/*cytology
NF-kappa B/*physiology
Tumor Necrosis Factor-alpha/*pharmacology
Animals ; Cell Culture Techniques ; Curcumin/pharmacology ; Interleukin-1beta/metabolism ; Mesenchymal Stem Cells/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Inbred Strains ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Osteogenesis/genetics ; Transduction, Genetic ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation.
Autorzy:
Wells JW; Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America. />Evans CH
Scott MC
Rütgen BC
O'Brien TD
Modiano JF
Cvetkovic G
Tepic S
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Źródło:
PloS one [PLoS One] 2013; Vol. 8 (1), pp. e54464. Date of Electronic Publication: 2013 Jan 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Arginase/*pharmacology
Arginine/*deficiency
Adult Stem Cells/cytology ; Adult Stem Cells/drug effects ; Adult Stem Cells/metabolism ; Animals ; Bone Neoplasms/drug therapy ; Bone Neoplasms/enzymology ; Bone Neoplasms/pathology ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Culture Media ; Dogs ; Leukemia/drug therapy ; Leukemia/enzymology ; Leukemia/pathology ; Lymphoma/drug therapy ; Lymphoma/enzymology ; Lymphoma/pathology ; Osteosarcoma/drug therapy ; Osteosarcoma/enzymology ; Osteosarcoma/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells.
Autorzy:
Haddad-Weber M; Orthopedic Center for Musculoskeletal Research, Department of Orthopedic Surgery, König-Ludwig-Haus, Julius-Maximilians-University, Würzburg, Germany. />Prager P
Kunz M
Seefried L
Jakob F
Murray MM
Evans CH
Nöth U
Steinert AF
Pokaż więcej
Źródło:
Cytotherapy [Cytotherapy] 2010 Jul; Vol. 12 (4), pp. 505-13.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Anterior Cruciate Ligament/*metabolism
Bone Morphogenetic Proteins/*metabolism
Fibroblasts/*metabolism
Growth Differentiation Factor 6/*metabolism
Growth Differentiation Factors/*metabolism
Mesenchymal Stem Cells/*metabolism
Adenoviridae ; Adult ; Aged ; Anterior Cruciate Ligament/pathology ; Bone Morphogenetic Proteins/genetics ; Cell Differentiation ; Cells, Cultured ; Extracellular Matrix Proteins/metabolism ; Female ; Fibroblasts/pathology ; Genetic Vectors ; Growth Differentiation Factor 6/genetics ; Growth Differentiation Factors/genetics ; Humans ; Hydrogel, Polyethylene Glycol Dimethacrylate/metabolism ; Immunohistochemistry ; Male ; Mesenchymal Stem Cells/pathology ; Middle Aged ; Polymerase Chain Reaction ; Tissue Engineering ; Transduction, Genetic ; Transgenes/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 50

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