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Wyświetlanie 61-80 z 119186
Tytuł:
Synthesis, α-Glucosidase inhibitory activity and docking studies of Novel Ethyl 1,2,3-triazol-4-ylmethylthio-5,6-diphenylpyridazine-4-carboxylate derivatives.
Autorzy:
Firoozpour, Loghman (AUTHOR)
Moghimi, Setareh (AUTHOR)
Salarinejad, Somayeh (AUTHOR)
Toolabi, Mahsa (AUTHOR)
Rafsanjani, Mahdi (AUTHOR)
Pakrad, Roya (AUTHOR)
Salmani, Farzaneh (AUTHOR)
Shokrolahi, Seyed Mohammad (AUTHOR)
Sadat Ebrahimi, Seyed Esmail (AUTHOR)
Karima, Saeed (AUTHOR)
Foroumadi, Alireza (AUTHOR)
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Źródło:
BMC Chemistry. 7/17/2023, Vol. 17 Issue 1, p1-10. 10p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis, Computational Studies, Antioxidant and Anti-Inflammatory Bio-Evaluation of 2,5-Disubstituted-1,3,4-Oxadiazole Derivatives.
Autorzy:
Rana, Sibghat Mansoor (AUTHOR)
Islam, Muhammad (AUTHOR)
Saeed, Hamid (AUTHOR)
Rafique, Hummera (AUTHOR)
Majid, Muhammad (AUTHOR)
Aqeel, Muhammad Tahir (AUTHOR)
Imtiaz, Fariha (AUTHOR)
Ashraf, Zaman (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). Jul2023, Vol. 16 Issue 7, p1045. 19p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
In Silico Screening and Anticancer-Apoptotic Evaluation of Newly Synthesized Thienopyrimidine/Sulfonamide Hybrids.
Autorzy:
Elmongy, Elshaymaa I. (AUTHOR)
Binjubair, Faizah A. (AUTHOR)
Alshehri, Ohoud Y. (AUTHOR)
Baeshen, Kholoud A. (AUTHOR)
Almukhalfi, Zaha A. (AUTHOR)
Henidi, Hanan A. (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Jul2023, Vol. 24 Issue 13, p10827. 18p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Chemical Synthesis, Safety and Efficacy of Antihypertensive Candidate Drug 221s (2,9).
Autorzy:
Qin, Bei (AUTHOR)
Yu, Lili (AUTHOR)
Wang, Rong (AUTHOR)
Tang, Yimei (AUTHOR)
Chen, Yunmei (AUTHOR)
Wang, Nana (AUTHOR)
Zhang, Yixin (AUTHOR)
Tan, Xiong (AUTHOR)
Yang, Kuan (AUTHOR)
Zhang, Bo (AUTHOR)
He, Maofang (AUTHOR)
Zhang, Yuzhen (AUTHOR)
Hu, Yaqi (AUTHOR)
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Źródło:
Molecules. Jul2023, Vol. 28 Issue 13, p4975. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel Thiazolidine-2,4-dione-trimethoxybenzene-thiazole Hybrids as Human Topoisomerases Inhibitors.
Autorzy:
Sinicropi, Maria Stefania (AUTHOR)
Ceramella, Jessica (AUTHOR)
Vanelle, Patrice (AUTHOR)
Iacopetta, Domenico (AUTHOR)
Rosano, Camillo (AUTHOR)
Khoumeri, Omar (AUTHOR)
Abdelmohsen, Shawkat (AUTHOR)
Abdelhady, Wafaa (AUTHOR)
El-Kashef, Hussein (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). Jul2023, Vol. 16 Issue 7, p946. 23p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis and antiproliferative activity of (5R)-cleistenolide and analogues.
Autorzy:
FARKAS, SÁNDOR
BENEDEKOVIĆ, GORAN
STANISAVLJEVIĆ, SLAĐANA M.
ZELENOVIĆ, BOJANA M. SREĆO
POPSAVIN, MIRJANA
POPSAVIN, VELIMIR
JAKIMOV, DIMITAR S.
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Alternatywny tytuł:
СИНТЕЗА И АНТИПРОЛИФЕРАТИВНА АКТИВНОСТ (5R)-КЛЕИСТЕНОЛИДА И АНАЛОГА
Źródło:
Journal of the Serbian Chemical Society. 2023, Vol. 88 Issue 7/8, p705-713. 9p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Optimization of the synthesis, in silico ADME/Tox profiling studies, and evaluation of the antimalarial activity of (7-chloroquinolin-4-ylthio)alkylbenzoate derivatives.
Autorzy:
Gutiérrez, Joyce E (AUTHOR)
Fernandez-Moreira, Esteban (AUTHOR)
Acosta, María E (AUTHOR)
Ramírez, Hegira (AUTHOR)
Charris, Jaime E (AUTHOR)
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Źródło:
Journal of Chemical Research. May/Jun2023, Vol. 47 Issue 3, p1-8. 8p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel Laser-Assisted Chemical Bath Synthesis of Pure and Silver-Doped Zinc Oxide Nanoparticles with Improved Antimicrobial and Photocatalytic Properties.
Autorzy:
Zyoud, Samer H. (AUTHOR)
Alalalmeh, Samer O. (AUTHOR)
Hegazi, Omar E. (AUTHOR)
Yahia, Ibrahim S. (AUTHOR)
Zahran, Heba Y. (AUTHOR)
Sara, Hamed Abu (AUTHOR)
Bloukh, Samir Haj (AUTHOR)
Shahwan, Moyad (AUTHOR)
Zyoud, Ahed H. (AUTHOR)
Hassan, Nageeb (AUTHOR)
Ashames, Akram (AUTHOR)
Daher, Malek G. (AUTHOR)
Makhadmeh, Ghaseb N. (AUTHOR)
Jairoun, Ammar (AUTHOR)
Qamhieh, Naser (AUTHOR)
Abdel-wahab, Mohamed Sh. (AUTHOR)
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Źródło:
Catalysts (2073-4344). May2023, Vol. 13 Issue 5, p900. 23p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Development of Novel Quinoline-Based Sulfonamides as Selective Cancer-Associated Carbonic Anhydrase Isoform IX Inhibitors.
Autorzy:
Shaldam M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Nocentini A; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, Sesto Fiorentino, 50019 Firenze, Italy.
Elsayed ZM; Scientific Research and Innovation Support Unit, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Ibrahim TM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.; Scientific Research and Innovation Support Unit, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Salem R; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
El-Domany RA; Department of Microbiology and Immunology, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Capasso C; Institute of Biosciences and Bioresources, Italian National Research Council (CNR)CNR, Via Pietro Castellino 111, 80131 Napoli, Italy.
Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, Sesto Fiorentino, 50019 Firenze, Italy.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.; Scientific Research and Innovation Support Unit, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 15; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:
Journal Article
MeSH Terms:
Carbonic Anhydrase Inhibitors*/chemical synthesis
Carbonic Anhydrase Inhibitors*/isolation & purification
Carbonic Anhydrase Inhibitors*/therapeutic use
Quinolines*/chemical synthesis
Quinolines*/isolation & purification
Quinolines*/therapeutic use
Sulfonamides*/chemical synthesis
Sulfonamides*/isolation & purification
Sulfonamides*/therapeutic use
Neoplasms/*drug therapy
Antigens, Neoplasm/genetics ; Antigens, Neoplasm/metabolism ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/isolation & purification ; Antineoplastic Agents/therapeutic use ; Carbonic Anhydrase IX/antagonists & inhibitors ; Carbonic Anhydrase IX/genetics ; Carbonic Anhydrase IX/metabolism ; Cell Line, Tumor ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; MCF-7 Cells ; Molecular Structure ; Neoplasms/genetics ; Structure-Activity Relationship
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Synthesis and Biological Assessment of 4,1-Benzothiazepines with Neuroprotective Activity on the Ca Overload for the Treatment of Neurodegenerative Diseases and Stroke.
Autorzy:
Viejo L; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.; Instituto de Investigación Sanitaria, Servicio de Farmacología Clínica, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Rubio-Alarcón M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Arribas RL; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Moreno-Castro M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Pérez-Marín R; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Braun-Cornejo M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
Estrada-Valencia M; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.
de Los Ríos C; Instituto-Fundación Teófilo Hernando and Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/Arzobispo Morcillo, 4, 28029 Madrid, Spain.; Instituto de Investigación Sanitaria, Servicio de Farmacología Clínica, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 24; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 24.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroprotective Agents*/chemical synthesis
Neuroprotective Agents*/pharmacology
Thiazepines*/chemical synthesis
Thiazepines*/pharmacology
Neurodegenerative Diseases/*drug therapy
Neurons/*drug effects
Neuroprotection/*drug effects
Stroke/*drug therapy
Animals ; Calcium/metabolism ; Calcium Channel Blockers/chemical synthesis ; Calcium Channel Blockers/pharmacology ; Calcium Signaling/drug effects ; Cell Line, Tumor ; Female ; Humans ; Mitochondria ; Neurons/pathology ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel Perbutyrylated Glucose Derivatives of (-)-Epigallocatechin-3-Gallate Inhibit Cancer Cells Proliferation by Decreasing Phosphorylation of the EGFR: Synthesis, Cytotoxicity, and Molecular Docking.
Autorzy:
Wang Y; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Shen XJ; Party Committee of Organ, Yunnan Agricultural University, Kunming 650201, China.
Su FW; State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China.
Xie YR; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Wang LX; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Zhang N; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Wu YL; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Niu Y; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Zhang DY; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.
Zi CT; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.
Wang XJ; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.
Sheng J; Key Laboratory of Pu-er Tea Science, Ministry of Education, College of Science, Yunnan Agricultural University, Kunming 650201, China.; College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 19; Vol. 26 (14). Date of Electronic Publication: 2021 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/chemical synthesis
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Cytotoxins*/chemical synthesis
Cytotoxins*/chemistry
Cytotoxins*/pharmacology
Glucose*/analogs & derivatives
Glucose*/chemical synthesis
Glucose*/chemistry
Glucose*/pharmacology
Molecular Docking Simulation*
Neoplasm Proteins*/biosynthesis
Neoplasm Proteins*/chemistry
Neoplasms*/chemistry
Neoplasms*/drug therapy
Neoplasms*/metabolism
Catechin/*analogs & derivatives
Cell Proliferation/*drug effects
A549 Cells ; Catechin/chemical synthesis ; Catechin/chemistry ; Catechin/pharmacology ; ErbB Receptors/biosynthesis ; ErbB Receptors/chemistry ; HL-60 Cells ; Humans ; MCF-7 Cells ; Phosphorylation/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Polyphenylglyoxamide-Based Amphiphilic Small Molecular Peptidomimetics as Antibacterial Agents with Anti-Biofilm Activity.
Autorzy:
Yu TT; School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
Kuppusamy R; School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.; School of Optometry and Vision Science, University of New South Wales, Sydney, NSW 2052, Australia.
Yasir M; School of Optometry and Vision Science, University of New South Wales, Sydney, NSW 2052, Australia.
Hassan MM; School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
Sara M; School of Optometry and Vision Science, University of New South Wales, Sydney, NSW 2052, Australia.
Ho J; School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
Willcox MDP; School of Optometry and Vision Science, University of New South Wales, Sydney, NSW 2052, Australia.
Black DS; School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
Kumar N; School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 08; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 08.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Bacterial Agents*/chemical synthesis
Anti-Bacterial Agents*/chemistry
Anti-Bacterial Agents*/pharmacology
Peptidomimetics*/chemical synthesis
Peptidomimetics*/chemistry
Peptidomimetics*/pharmacology
Biofilms/*drug effects
Escherichia coli/*physiology
Staphylococcus aureus/*physiology
Biofilms/growth & development ; Structure-Activity Relationship ; Sulfonylurea Compounds/chemical synthesis ; Sulfonylurea Compounds/chemistry ; Sulfonylurea Compounds/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Toward Multitasking Pharmacological COX-Targeting Agents: Non-Steroidal Anti-Inflammatory Prodrugs with Antiproliferative Effects.
Autorzy:
Grande F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Ampl. Polifunzionale, Via P. Bucci, 87036 Rende, Italy.
Giordano F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Ampl. Polifunzionale, Via P. Bucci, 87036 Rende, Italy.
Occhiuzzi MA; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Ampl. Polifunzionale, Via P. Bucci, 87036 Rende, Italy.
Rocca C; Department of Biology, Ecology and Earth Sciences, University of Calabria, Via P. Bucci, 87036 Rende, Italy.
Ioele G; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Ampl. Polifunzionale, Via P. Bucci, 87036 Rende, Italy.
De Luca M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Ampl. Polifunzionale, Via P. Bucci, 87036 Rende, Italy.
Ragno G; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Ampl. Polifunzionale, Via P. Bucci, 87036 Rende, Italy.
Panno ML; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Ampl. Polifunzionale, Via P. Bucci, 87036 Rende, Italy.
Rizzuti B; CNR-NANOTEC, SS Rende (CS), Department of Physics, University of Calabria, Via P. Bucci, 87036 Rende, Italy.; Institute of Biocomputation and Physics of Complex Systems (BIFI), Joint Units IQFR-CSIC-BIFI, and GBsC-CSIC-BIFI, University of Zaragoza, 50018 Zaragoza, Spain.
Garofalo A; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Ampl. Polifunzionale, Via P. Bucci, 87036 Rende, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 28; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 28.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Inflammatory Agents, Non-Steroidal*/chemical synthesis
Anti-Inflammatory Agents, Non-Steroidal*/chemistry
Anti-Inflammatory Agents, Non-Steroidal*/pharmacology
Cyclooxygenase Inhibitors*/chemical synthesis
Cyclooxygenase Inhibitors*/chemistry
Cyclooxygenase Inhibitors*/pharmacology
Nabumetone*/chemical synthesis
Nabumetone*/chemistry
Nabumetone*/pharmacology
Cell Proliferation/*drug effects
Humans ; MCF-7 Cells ; Prodrugs/chemical synthesis ; Prodrugs/chemistry ; Prodrugs/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 61-80 z 119186

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