Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""CHO Cells"" wg kryterium: Temat


Tytuł :
Characterization of Chinese hamster ovary cells with disparate chromosome numbers: Reduction of the amount of mRNA relative to total protein.
Autorzy :
Yamano-Adachi N; Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: .
Ogata N; Nihon BioData Corporation, 3-2-1 Sakado, Takatsu-ku, Kawasaki, Kanagawa 213-0012, Japan. Electronic address: .
Tanaka S; Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: .
Onitsuka M; Graduate School of Technology, Industrial and Social Sciences, Tokushima University, 2-1 Minamijosanjima-cho, Tokushima, Tokushima 770-8506, Japan. Electronic address: .
Omasa T; Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: .
Pokaż więcej
Źródło :
Journal of bioscience and bioengineering [J Biosci Bioeng] 2020 Jan; Vol. 129 (1), pp. 121-128. Date of Electronic Publication: 2019 Jul 11.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Society for Bioscience and Bioengineering, Japan Country of Publication: Japan NLM ID: 100888800 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-4421 (Electronic) Linking ISSN: 13474421 NLM ISO Abbreviation: J. Biosci. Bioeng. Subsets: MEDLINE
MeSH Terms :
CHO Cells/*metabolism
Chromosomes/*genetics
Immunoglobulin G/*biosynthesis
RNA, Messenger/*genetics
Animals ; CHO Cells/cytology ; Chromosomes/metabolism ; Cricetinae ; Cricetulus ; Gene Expression ; Immunoglobulin G/genetics ; RNA, Messenger/metabolism ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/genetics ; Transcriptome
Czasopismo naukowe
Tytuł :
Novel Promoters Derived from Chinese Hamster Ovary Cells via In Silico and In Vitro Analysis.
Autorzy :
Nguyen LN; Department of Biotechnology, BOKU University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.; Austrian Center of Industrial Biotechnology GmbH, 1190, Vienna, Austria.
Baumann M; Austrian Center of Industrial Biotechnology GmbH, 1190, Vienna, Austria.
Dhiman H; Department of Biotechnology, BOKU University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.; Austrian Center of Industrial Biotechnology GmbH, 1190, Vienna, Austria.
Marx N; Department of Biotechnology, BOKU University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.; Austrian Center of Industrial Biotechnology GmbH, 1190, Vienna, Austria.
Schmieder V; Department of Biotechnology, BOKU University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.; Austrian Center of Industrial Biotechnology GmbH, 1190, Vienna, Austria.
Hussein M; Department of Biotechnology, BOKU University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.; Austrian Center of Industrial Biotechnology GmbH, 1190, Vienna, Austria.
Eisenhut P; Department of Biotechnology, BOKU University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.; Austrian Center of Industrial Biotechnology GmbH, 1190, Vienna, Austria.
Hernandez I; Austrian Center of Industrial Biotechnology GmbH, 1190, Vienna, Austria.
Koehn J; Rentschler Biopharma, 88471, Laupheim, Germany.
Borth N; Department of Biotechnology, BOKU University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria.; Austrian Center of Industrial Biotechnology GmbH, 1190, Vienna, Austria.
Pokaż więcej
Źródło :
Biotechnology journal [Biotechnol J] 2019 Nov; Vol. 14 (11), pp. e1900125. Date of Electronic Publication: 2019 Aug 09.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101265833 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7314 (Electronic) Linking ISSN: 18606768 NLM ISO Abbreviation: Biotechnol J Subsets: MEDLINE
MeSH Terms :
CHO Cells*
Gene Expression*
Promoter Regions, Genetic*
Genetic Enhancement/*methods
Recombinant Proteins/*biosynthesis
Recombinant Proteins/*genetics
Animals ; Cell Culture Techniques ; Cell Engineering ; Cloning, Molecular ; Computer Simulation ; Cricetinae ; Cricetulus ; Epigenesis, Genetic ; Escherichia coli/genetics ; Humans ; In Vitro Techniques ; Transgenes/genetics
Czasopismo naukowe
Tytuł :
[Establishment of Flp-In TM CHO cell lines with double expression of CYP2A13 and MRP2].
Autorzy :
Liu X; Guizhou Provincial Key Laboratory of Pharmaceutics/State Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, Guiyang 550004, China.
He J; Guizhou Provincial Key Laboratory of Pharmaceutics/State Key Laboratory of Functions and Applications of Medicinal Plants, School of Pharmacy, Guiyang 550004, China.
Yang C; Guizhou Provincial Key Laboratory of Pharmaceutics/State Key Laboratory of Functions and Applications of Medicinal Plants, Guiyang 550004, China.
Wang Y; Guizhou Provincial Key Laboratory of Pharmaceutics/State Key Laboratory of Functions and Applications of Medicinal Plants, Guiyang 550004, China.
Xue W; School of Medicine and Health Management, Guizhou Medical University, Guiyang 550004, China.
He B; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM(Ministry of Education), Guiyang 550004, China.
Li Y; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM(Ministry of Education), Guiyang 550004, China.
Lan Y; Engineering Research Center for the Development and Application of Ethnic Medicine and TCM(Ministry of Education), Guiyang 550004, China.
Liu T; Guizhou Provincial Key Laboratory of Pharmaceutics/State Key Laboratory of Functions and Applications of Medicinal Plants, Guiyang 550004, China. *Corresponding author, E-mail: .
Pokaż więcej
Źródło :
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi] 2019 Oct; Vol. 35 (10), pp. 865-871.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Xi bao yu fen zi mian yi xue za zhi bian ji bu Country of Publication: China NLM ID: 101139110 Publication Model: Print Cited Medium: Print ISSN: 1007-8738 (Print) Linking ISSN: 10078738 NLM ISO Abbreviation: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi Subsets: MEDLINE
MeSH Terms :
CHO Cells*
Aryl Hydrocarbon Hydroxylases/*genetics
Multidrug Resistance-Associated Proteins/*genetics
Animals ; Carcinogens/toxicity ; Cricetinae ; Cricetulus ; Nitrosamines/toxicity ; Plasmids ; Transfection
Czasopismo naukowe
Tytuł :
Optimized dual assay for the transgenes selection and screening in CHO cell line development for recombinant protein production.
Autorzy :
Beketova EV; School of Biology, Moscow State University, Leninskie gori 1/12, Moscow, Russia, 119234.
Ibneeva LR; School of Biology, Moscow State University, Leninskie gori 1/12, Moscow, Russia, 119234.
Abdulina YA; HyTest Ltd, Intelligate 1, 6th Floor, Joukahaisenkatu 6, 20520, Turku, Finland.
Dergousova EA; HyTest Ltd, Intelligate 1, 6th Floor, Joukahaisenkatu 6, 20520, Turku, Finland.
Filatov VL; HyTest Ltd, Intelligate 1, 6th Floor, Joukahaisenkatu 6, 20520, Turku, Finland.
Kozlovsky SV; HyTest Ltd, Intelligate 1, 6th Floor, Joukahaisenkatu 6, 20520, Turku, Finland.
Shilov ES; School of Biology, Moscow State University, Leninskie gori 1/12, Moscow, Russia, 119234.
Datskevich PN; School of Biology, Moscow State University, Leninskie gori 1/12, Moscow, Russia, 119234.
Rozov FN; HyTest Ltd, Intelligate 1, 6th Floor, Joukahaisenkatu 6, 20520, Turku, Finland. .; School of Biology, Moscow State University, Leninskie gori 1/12, Moscow, Russia, 119234. .
Pokaż więcej
Źródło :
Biotechnology letters [Biotechnol Lett] 2019 Sep; Vol. 41 (8-9), pp. 929-939. Date of Electronic Publication: 2019 Jul 18.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8008051 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6776 (Electronic) Linking ISSN: 01415492 NLM ISO Abbreviation: Biotechnol. Lett. Subsets: MEDLINE
MeSH Terms :
CHO Cells*
Cell Proliferation*
Biotechnology/*methods
Cytological Techniques/*methods
Mass Screening/*methods
Recombinant Proteins/*metabolism
Animals ; Cricetulus ; Recombinant Proteins/genetics ; Staining and Labeling/methods
Czasopismo naukowe
Tytuł :
Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics.
Autorzy :
Lin PC; a Bioprocessing Technology Institute, Agency for Science , Technology and Research (A*STAR) , Singapore.
Chan KF; a Bioprocessing Technology Institute, Agency for Science , Technology and Research (A*STAR) , Singapore.
Kiess IA; a Bioprocessing Technology Institute, Agency for Science , Technology and Research (A*STAR) , Singapore.
Tan J; a Bioprocessing Technology Institute, Agency for Science , Technology and Research (A*STAR) , Singapore.
Shahreel W; a Bioprocessing Technology Institute, Agency for Science , Technology and Research (A*STAR) , Singapore.
Wong SY; a Bioprocessing Technology Institute, Agency for Science , Technology and Research (A*STAR) , Singapore.
Song Z; a Bioprocessing Technology Institute, Agency for Science , Technology and Research (A*STAR) , Singapore.; b Department of Biochemistry , Yong Loo Lin School of Medicine, National University of Singapore , Singapore.
Pokaż więcej
Źródło :
MAbs [MAbs] 2019 Jul; Vol. 11 (5), pp. 965-976. Date of Electronic Publication: 2019 Jun 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE
MeSH Terms :
Antibodies, Monoclonal/*biosynthesis
CHO Cells/*immunology
Glutamate-Ammonia Ligase/*genetics
Animals ; Antibodies, Monoclonal/genetics ; Antibodies, Monoclonal/immunology ; CHO Cells/enzymology ; Cricetulus ; Humans ; Methionine Sulfoximine/pharmacology ; Transfection
Czasopismo naukowe
Tytuł :
Human genome-derived TOP1 matrix attachment region enhances transgene expression in the transfected CHO cells.
Autorzy :
Jia YL; School of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, Henan, China.; International Joint Research Laboratory for Recombiant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
Guo X; School of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, Henan, China.; International Joint Research Laboratory for Recombiant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
Wang XC; School of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, Henan, China.; International Joint Research Laboratory for Recombiant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
Wang TY; International Joint Research Laboratory for Recombiant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, 453003, Henan, China. .; School of Basic Medicine, Xinxiang Medical University, Xinxiang, 453003, Henan, China. .
Pokaż więcej
Źródło :
Biotechnology letters [Biotechnol Lett] 2019 Jul; Vol. 41 (6-7), pp. 701-709. Date of Electronic Publication: 2019 Apr 05.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8008051 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6776 (Electronic) Linking ISSN: 01415492 NLM ISO Abbreviation: Biotechnol. Lett. Subsets: MEDLINE
MeSH Terms :
CHO Cells*
Gene Expression*
Matrix Attachment Regions*
Cell Engineering/*methods
DNA Topoisomerases, Type I/*genetics
Green Fluorescent Proteins/*biosynthesis
Recombinant Proteins/*biosynthesis
Animals ; Cricetulus ; Green Fluorescent Proteins/genetics ; Humans ; Recombinant Proteins/genetics
Czasopismo naukowe
Tytuł :
Assessment of false transmitters as treatments for nerve agent poisoning.
Autorzy :
Whitmore C; Chemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK. Electronic address: .
Lindsay CD; Chemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Bird M; Chemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Gore SJ; Chemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Rice H; Chemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Williams RL; Chemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Timperley CM; Chemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Green AC; Chemical, Biological and Radiological Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire, SP4 0JQ, UK.
Pokaż więcej
Źródło :
Toxicology letters [Toxicol Lett] 2020 Mar 15; Vol. 321, pp. 21-31. Date of Electronic Publication: 2019 Dec 09.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3169 (Electronic) Linking ISSN: 03784274 NLM ISO Abbreviation: Toxicol. Lett. Subsets: MEDLINE
MeSH Terms :
Acetylcholine/*analogs & derivatives
Antidotes/*pharmacology
Choline/*analogs & derivatives
Cholinesterase Inhibitors/*poisoning
Diaphragm/*innervation
Nerve Agents/*poisoning
Neurotransmitter Agents/*pharmacology
Organophosphate Poisoning/*drug therapy
Soman/*poisoning
Synapses/*drug effects
Acetylcholine/chemical synthesis ; Acetylcholine/metabolism ; Acetylcholine/pharmacology ; Acetylcholinesterase/metabolism ; Animals ; Antidotes/chemical synthesis ; CHO Cells ; Cell Line, Tumor ; Choline/chemical synthesis ; Choline/pharmacology ; Cricetulus ; Drug Partial Agonism ; Guinea Pigs ; Humans ; Male ; Neurotransmitter Agents/chemical synthesis ; Organophosphate Poisoning/enzymology ; Organophosphate Poisoning/physiopathology ; Receptors, Cholinergic/drug effects ; Receptors, Cholinergic/genetics ; Receptors, Cholinergic/metabolism ; Synapses/enzymology
Czasopismo naukowe
Tytuł :
Comparative cytotoxicity of halogenated aromatic DBPs and implications of the corresponding developed QSAR model to toxicity mechanisms of those DBPs: Binding interactions between aromatic DBPs and catalase play an important role.
Autorzy :
Zhang Z; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Zhu Q; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Huang C; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Yang M; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China. Electronic address: .
Li J; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Chen Y; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Yang B; College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, China.
Zhao X; State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Pokaż więcej
Źródło :
Water research [Water Res] 2020 Mar 01; Vol. 170, pp. 115283. Date of Electronic Publication: 2019 Nov 08.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Pergamon Press Country of Publication: England NLM ID: 0105072 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2448 (Electronic) Linking ISSN: 00431354 NLM ISO Abbreviation: Water Res. Subsets: MEDLINE
MeSH Terms :
Disinfectants*
Drinking Water*
Water Pollutants, Chemical*
Water Purification*
Animals ; CHO Cells ; Catalase ; China ; Cricetinae ; Cricetulus ; Disinfection ; Halogenation ; Humans ; Molecular Docking Simulation ; Quantitative Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Multi-target dopamine D3 receptor modulators: Actionable knowledge for drug design from molecular dynamics and machine learning.
Autorzy :
Ferraro M; Istituto di Chimica Del Riconoscimento Molecolare, Consiglio Nazionale Delle Ricerche (ICRM-CNR), Via Mario Bianco 9, 20131, Milan, Italy. Electronic address: .
Decherchi S; Computational & Chemical Biology, Italian Institute of Technology, Via Morego 30, 16163, Genoa, Italy. Electronic address: .
De Simone A; Sygnature Discovery Ltd, Bio City, Pennyfoot St, Nottingham NG1 1GR, United Kingdom. Electronic address: .
Recanatini M; Dept. of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy. Electronic address: .
Cavalli A; Computational & Chemical Biology, Italian Institute of Technology, Via Morego 30, 16163, Genoa, Italy; Dept. of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, 40126, Bologna, Italy. Electronic address: .
Bottegoni G; School of Pharmacy, University of Birmingham, Sir Robert Aitken Institute for Clinical Research, Edgbaston, B15 2TT, United Kingdom. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2020 Feb 15; Vol. 188, pp. 111975. Date of Electronic Publication: 2019 Dec 23.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
MeSH Terms :
Carbamates/*metabolism
Dopamine Agonists/*metabolism
Dopamine Antagonists/*metabolism
Piperazines/*metabolism
Receptors, Dopamine D3/*metabolism
Animals ; Binding Sites ; CHO Cells ; Carbamates/chemistry ; Cricetulus ; Dopamine Agonists/chemistry ; Dopamine Antagonists/chemistry ; Drug Design ; Humans ; Ligands ; Machine Learning ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Piperazines/chemistry ; Protein Conformation ; Receptors, Dopamine D3/chemistry ; Salicylamides/metabolism
Czasopismo naukowe
Tytuł :
Developing an equivalent toxicity area approach to comparing toxicity of urban road deposited sediments.
Autorzy :
Zhan Y; College of Chemistry and Environmental Engineering, Shenzhen University, 518060 Shenzhen, China.
Yang B; College of Chemistry and Environmental Engineering, Shenzhen University, 518060 Shenzhen, China.
Hong N; College of Chemistry and Environmental Engineering, Shenzhen University, 518060 Shenzhen, China.
Guan Y; College of Chemistry and Environmental Engineering, Shenzhen University, 518060 Shenzhen, China.
Liu A; College of Chemistry and Environmental Engineering, Shenzhen University, 518060 Shenzhen, China. Electronic address: .
Du Y; Guangdong Provincial Engineering Technology Research Centre for Urban Water Cycle and Water Environment Safety, Graduate School at Shenzhen, Tsinghua University, 518055, Shenzhen, China.
Wu Q; Guangdong Provincial Engineering Technology Research Centre for Urban Water Cycle and Water Environment Safety, Graduate School at Shenzhen, Tsinghua University, 518055, Shenzhen, China.
Guan Y; Guangdong Provincial Engineering Technology Research Centre for Urban Water Cycle and Water Environment Safety, Graduate School at Shenzhen, Tsinghua University, 518055, Shenzhen, China.
Pokaż więcej
Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2020 Feb; Vol. 257, pp. 113588. Date of Electronic Publication: 2019 Nov 08.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8804476 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6424 (Electronic) Linking ISSN: 02697491 NLM ISO Abbreviation: Environ. Pollut. Subsets: MEDLINE
MeSH Terms :
Environmental Monitoring*
Environmental Pollutants/*toxicity
Toxicity Tests/*methods
Animals ; CHO Cells ; China ; Cricetinae ; Cricetulus ; Rain
Czasopismo naukowe
Tytuł :
Cardiotoxic effects of [3-[2-(diethylamino)ethyl]-1H-indol-4-yl] acetate and 3-[2-[ethyl(methyl)amino]ethyl]-1H-indol-4-ol.
Autorzy :
Yoon KS; National Institute of Drug and Safety Evaluation, Ministry of Food and Drug Safety, Osong, Cheongju, Republic of Korea. Electronic address: .
Lee JM; National Institute of Drug and Safety Evaluation, Ministry of Food and Drug Safety, Osong, Cheongju, Republic of Korea. Electronic address: .
Kim YH; National Institute of Drug and Safety Evaluation, Ministry of Food and Drug Safety, Osong, Cheongju, Republic of Korea. Electronic address: .
Suh SK; National Institute of Drug and Safety Evaluation, Ministry of Food and Drug Safety, Osong, Cheongju, Republic of Korea. Electronic address: .
Cha HJ; National Institute of Drug and Safety Evaluation, Ministry of Food and Drug Safety, Osong, Cheongju, Republic of Korea. Electronic address: .
Pokaż więcej
Źródło :
Toxicology letters [Toxicol Lett] 2020 Feb 01; Vol. 319, pp. 40-48. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3169 (Electronic) Linking ISSN: 03784274 NLM ISO Abbreviation: Toxicol. Lett. Subsets: MEDLINE
MeSH Terms :
Cardiotoxins/*toxicity
Hallucinogens/*toxicity
Tryptamines/*toxicity
Animals ; CHO Cells ; Cell Line ; Cell Survival/drug effects ; Cricetulus ; ERG1 Potassium Channel/metabolism ; Electrocardiography ; Male ; Myocytes, Cardiac/drug effects ; Potassium Channel Blockers/toxicity ; Rats ; Rats, Sprague-Dawley ; p21-Activated Kinases/biosynthesis ; p21-Activated Kinases/genetics
Czasopismo naukowe
Tytuł :
Physiological responses of Chinese hamster ovary cells to a productivity-enhancing yeast extract.
Autorzy :
Hu D; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Zhao L; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Wang J; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Fan L; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Liu X; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Wang H; Zhejiang Hisun Pharmaceutical Co. Ltd., Fuyang, Hangzhou, Zhejiang 311404, China.
Tan WS; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China. Electronic address: .
Pokaż więcej
Źródło :
Journal of bioscience and bioengineering [J Biosci Bioeng] 2018 Nov; Vol. 126 (5), pp. 636-643. Date of Electronic Publication: 2018 May 28.
Typ publikacji :
Comparative Study; Evaluation Study; Journal Article
Journal Info :
Publisher: Society for Bioscience and Bioengineering, Japan Country of Publication: Japan NLM ID: 100888800 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1347-4421 (Electronic) Linking ISSN: 13474421 NLM ISO Abbreviation: J. Biosci. Bioeng. Subsets: MEDLINE
MeSH Terms :
CHO Cells/*drug effects
CHO Cells/*physiology
Cell Engineering/*methods
Cell Extracts/*pharmacology
Yeasts/*chemistry
Animals ; CHO Cells/cytology ; Cell Culture Techniques ; Cell Proliferation/drug effects ; Cricetinae ; Cricetulus ; Energy Metabolism/drug effects ; Protein Biosynthesis/drug effects ; Recombinant Proteins/drug effects ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
High throughput, efficacious gene editing & genome surveillance in Chinese hamster ovary cells.
Autorzy :
Huhn SC; Cell Line Development, Merck & Co., Inc., Kenilworth, NJ, United States of America.
Ou Y; Cell Line Development, Merck & Co., Inc., Kenilworth, NJ, United States of America.
Kumar A; Cell Line Development, Merck & Co., Inc., Kenilworth, NJ, United States of America.
Liu R; Cell Line Development, Merck & Co., Inc., Kenilworth, NJ, United States of America.
Du Z; Cell Line Development, Merck & Co., Inc., Kenilworth, NJ, United States of America.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2019 Dec 19; Vol. 14 (12), pp. e0218653. Date of Electronic Publication: 2019 Dec 19 (Print Publication: 2019).
Typ publikacji :
Journal Article
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS ONE Subsets: MEDLINE
MeSH Terms :
CHO Cells/*metabolism
CHO Cells/*physiology
Genetic Engineering/*methods
Animals ; CRISPR-Cas Systems ; Clustered Regularly Interspaced Short Palindromic Repeats ; Cricetinae/genetics ; Cricetulus ; Gene Editing/methods ; Genome/genetics ; High-Throughput Screening Assays/methods
Czasopismo naukowe
Tytuł :
Method validation of Q-PCR detection of host residual DNA in antibody drug based on protein A magnetic beads.
Autorzy :
Liu XZ; State Key Laboratory of Antibody Research, Development, New Drug Research and Development Company Ltd., North China PharmaceuticalCorporation, Shijiazhuang, 050015, China.
Zhang B; State Key Laboratory of Antibody Research, Development, New Drug Research and Development Company Ltd., North China PharmaceuticalCorporation, Shijiazhuang, 050015, China.
Zhao W; State Key Laboratory of Antibody Research, Development, New Drug Research and Development Company Ltd., North China PharmaceuticalCorporation, Shijiazhuang, 050015, China.
Li G; State Key Laboratory of Antibody Research, Development, New Drug Research and Development Company Ltd., North China PharmaceuticalCorporation, Shijiazhuang, 050015, China.
Zhou ML; State Key Laboratory of Antibody Research, Development, New Drug Research and Development Company Ltd., North China PharmaceuticalCorporation, Shijiazhuang, 050015, China.
Wei JS; State Key Laboratory of Antibody Research, Development, New Drug Research and Development Company Ltd., North China PharmaceuticalCorporation, Shijiazhuang, 050015, China.
Zhou JH; Key Laboratory for Family Planning and Healthy Birth, National Health and Family Planning Commision, Hebei Research Institute for Family Planning, Shijiazhuang, 050071, China.
Gao J; State Key Laboratory of Antibody Research, Development, New Drug Research and Development Company Ltd., North China PharmaceuticalCorporation, Shijiazhuang, 050015, China. Electronic address: .
Wang ZM; State Key Laboratory of Antibody Research, Development, New Drug Research and Development Company Ltd., North China PharmaceuticalCorporation, Shijiazhuang, 050015, China.
Pokaż więcej
Źródło :
Biologicals : journal of the International Association of Biological Standardization [Biologicals] 2019 Nov; Vol. 62, pp. 65-71. Date of Electronic Publication: 2019 Sep 18.
Typ publikacji :
Journal Article; Validation Study
Journal Info :
Publisher: Academic Press Country of Publication: England NLM ID: 9004494 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8320 (Electronic) Linking ISSN: 10451056 NLM ISO Abbreviation: Biologicals Subsets: MEDLINE
MeSH Terms :
Real-Time Polymerase Chain Reaction*
Antibodies, Monoclonal/*analysis
DNA/*analysis
Staphylococcal Protein A/*chemistry
Animals ; Antibodies, Monoclonal/chemistry ; CHO Cells ; Cricetulus ; DNA/genetics ; Magnetic Phenomena
Czasopismo naukowe
Tytuł :
Systematic development of temperature shift strategies for Chinese hamster ovary cells based on short duration cultures and kinetic modeling.
Autorzy :
Xu J; a Global Product Development and Supply , Bristol-Myers Squibb Company , Devens , MA , USA.
Tang P; b Department of Paper and Bioprocess Engineering , SUNY-ESF , Syracuse , NY , USA.
Yongky A; a Global Product Development and Supply , Bristol-Myers Squibb Company , Devens , MA , USA.
Drew B; a Global Product Development and Supply , Bristol-Myers Squibb Company , Devens , MA , USA.
Borys MC; a Global Product Development and Supply , Bristol-Myers Squibb Company , Devens , MA , USA.
Liu S; b Department of Paper and Bioprocess Engineering , SUNY-ESF , Syracuse , NY , USA.
Li ZJ; a Global Product Development and Supply , Bristol-Myers Squibb Company , Devens , MA , USA.
Pokaż więcej
Źródło :
MAbs [MAbs] 2019 Jan; Vol. 11 (1), pp. 191-204. Date of Electronic Publication: 2018 Oct 02.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE
MeSH Terms :
Antibodies, Monoclonal*
CHO Cells*
Cell Culture Techniques/*methods
Animals ; Bioreactors/standards ; Cell Proliferation ; Cricetinae ; Cricetulus ; Kinetics ; Temperature
Czasopismo naukowe
Tytuł :
3-Quinuclidinyl-α-methoxydiphenylacetate: A multi-targeted ligand with antimuscarinic and antinicotinic effects designed for the treatment of anticholinesterase poisoning.
Autorzy :
Timperley CM; Chemical, Biological and Radiological (CBR) Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire SP4 0JQ, UK. Electronic address: .
Bird M; Chemical, Biological and Radiological (CBR) Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Gore SJ; Chemical, Biological and Radiological (CBR) Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Lindsay CD; Chemical, Biological and Radiological (CBR) Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Rice H; Chemical, Biological and Radiological (CBR) Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Tattersall JEH; Chemical, Biological and Radiological (CBR) Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Whitmore CL; Chemical, Biological and Radiological (CBR) Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Green AC; Chemical, Biological and Radiological (CBR) Division, Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, Wiltshire SP4 0JQ, UK.
Pokaż więcej
Źródło :
Toxicology letters [Toxicol Lett] 2020 Jun 01; Vol. 325, pp. 67-76. Date of Electronic Publication: 2020 Feb 01.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3169 (Electronic) Linking ISSN: 03784274 NLM ISO Abbreviation: Toxicol. Lett. Subsets: MEDLINE
MeSH Terms :
Antidotes/*pharmacology
Antidotes/*therapeutic use
Cholinesterase Inhibitors/*poisoning
Muscarinic Antagonists/*pharmacology
Muscarinic Antagonists/*therapeutic use
Nerve Agents/*poisoning
Nicotinic Antagonists/*pharmacology
Nicotinic Antagonists/*therapeutic use
Animals ; Anticonvulsants/chemistry ; Anticonvulsants/therapeutic use ; Antidotes/chemical synthesis ; CHO Cells ; Cell Line ; Cricetinae ; Cricetulus ; Diaphragm/drug effects ; Guinea Pigs ; Humans ; In Vitro Techniques ; Male ; Muscarinic Antagonists/chemical synthesis ; Muscle, Skeletal/drug effects ; Neurons/drug effects ; Nicotinic Antagonists/chemical synthesis ; Seizures/chemically induced ; Seizures/prevention & control ; Soman/poisoning
Czasopismo naukowe
Tytuł :
Meta-Analysis of Publicly Available Chinese Hamster Ovary (CHO) Cell Transcriptomic Datasets for Identifying Engineering Targets to Enhance Recombinant Protein Yields.
Autorzy :
Tamošaitis L; Industrial Biotechnology Centre and School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
Smales CM; Industrial Biotechnology Centre and School of Biosciences, University of Kent, Canterbury, Kent CT2 7NJ, UK.
Pokaż więcej
Źródło :
Biotechnology journal [Biotechnol J] 2018 Oct; Vol. 13 (10), pp. e1800066. Date of Electronic Publication: 2018 Jul 05.
Typ publikacji :
Journal Article; Meta-Analysis
Journal Info :
Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101265833 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7314 (Electronic) Linking ISSN: 18606768 NLM ISO Abbreviation: Biotechnol J
MeSH Terms :
CHO Cells*
Databases, Genetic*
Recombinant Proteins*/biosynthesis
Recombinant Proteins*/genetics
Transcriptome*
Animals ; Cricetulus ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
An Online Compendium of CHO RNA-Seq Data Allows Identification of CHO Cell Line-Specific Transcriptomic Signatures.
Autorzy :
Singh A; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.; Department of Biotechnology and Biomedicine, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Kildegaard HF; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Andersen MR; Department of Biotechnology and Biomedicine, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark.
Pokaż więcej
Źródło :
Biotechnology journal [Biotechnol J] 2018 Oct; Vol. 13 (10), pp. e1800070. Date of Electronic Publication: 2018 Jul 05.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101265833 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7314 (Electronic) Linking ISSN: 18606768 NLM ISO Abbreviation: Biotechnol J
MeSH Terms :
CHO Cells*/classification
Transcriptome*
RNA/*genetics
Animals ; Cricetulus ; Gene Expression Profiling ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
[Eukaryotic expression, protein purification and biological effects research of human CS1-Fc fusion protein].
Autorzy :
Chen R; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
Wang X; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
Li Y; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
Gao J; School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
Pokaż więcej
Źródło :
Sheng wu gong cheng xue bao = Chinese journal of biotechnology [Sheng Wu Gong Cheng Xue Bao] 2020 Jan 25; Vol. 36 (1), pp. 122-132.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Ke xue chu ban she Country of Publication: China NLM ID: 9426463 Publication Model: Print Cited Medium: Internet ISSN: 1000-3061 (Print) Linking ISSN: 10003061 NLM ISO Abbreviation: Sheng Wu Gong Cheng Xue Bao Subsets: MEDLINE
MeSH Terms :
Eukaryota*
Multiple Myeloma*
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Humans ; Recombinant Fusion Proteins ; Recombinant Proteins
Czasopismo naukowe
Tytuł :
Chlorinated effluent organic matter causes higher toxicity than chlorinated natural organic matter by inducing more intracellular reactive oxygen species.
Autorzy :
Du Y; Key Laboratory of Microorganism Application and Risk Control of Shenzhen, Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental Safety, Tsinghua Shenzhen International Graduate School, Shenzhen 518055, China.
Wang WL; Environmental Simulation and Pollution Control State Key Joint Laboratory, State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (SMARC), School of Environment, Tsinghua University, Beijing 100084, China.
He T; South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou, China.
Sun YX; Department of Environmental Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.
Lv XT; Key Laboratory of Microorganism Application and Risk Control of Shenzhen, Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental Safety, Tsinghua Shenzhen International Graduate School, Shenzhen 518055, China.
Wu QY; Key Laboratory of Microorganism Application and Risk Control of Shenzhen, Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental Safety, Tsinghua Shenzhen International Graduate School, Shenzhen 518055, China. Electronic address: .
Hu HY; Environmental Simulation and Pollution Control State Key Joint Laboratory, State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (SMARC), School of Environment, Tsinghua University, Beijing 100084, China.
Pokaż więcej
Źródło :
The Science of the total environment [Sci Total Environ] 2020 Jan 20; Vol. 701, pp. 134881. Date of Electronic Publication: 2019 Nov 01.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0330500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1026 (Electronic) Linking ISSN: 00489697 NLM ISO Abbreviation: Sci. Total Environ. Subsets: MEDLINE
MeSH Terms :
Halogenation*
Water Purification*
Water Pollutants, Chemical/*toxicity
Animals ; CHO Cells ; Cricetulus ; Disinfection ; Toxicity Tests
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies