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Wyszukujesz frazę ""CHO Cells"" wg kryterium: Temat


Tytuł :
Hyperosmolality in CHO cell culture: effects on the proteome.
Autorzy :
Romanova N; Cell Culture Technology, Technical Faculty, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany.
Schelletter L; Cell Culture Technology, Technical Faculty, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany.
Hoffrogge R; Cell Culture Technology, Technical Faculty, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany.
Noll T; Cell Culture Technology, Technical Faculty, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany. .
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Źródło :
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2022 Apr; Vol. 106 (7), pp. 2569-2586. Date of Electronic Publication: 2022 Mar 21.
Typ publikacji :
Journal Article
MeSH Terms :
CHO Cells*/metabolism
Cell Culture Techniques*
Proteome*
Animals ; Cricetinae ; Cricetulus ; Osmolar Concentration
Czasopismo naukowe
Tytuł :
Rapid cGMP manufacturing of COVID-19 monoclonal antibody using stable CHO cell pools.
Autorzy :
Agostinetto R; MerckSerono S.p.A, Guidonia di Montecello, Italy.
Rossi M; MerckSerono S.p.A, Guidonia di Montecello, Italy.
Dawson J; EMD Serono, Billerica, Massachusetts, USA.
Lim A; EMD Serono, Billerica, Massachusetts, USA.
Simoneau MH; Ares Trading SA/Merck SA Switzerland, Aubonne, Switzerland.
Boucher C; Ares Trading SA/Merck SA Switzerland, Aubonne, Switzerland.
Valldorf B; Merck KGaA, Darmstadt, Germany.
Ross-Gillespie A; Ares Trading SA/Merck SA Switzerland, Aubonne, Switzerland.
Jardine JG; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, USA.; IAVI, New York, New York, USA.; IAVI, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, USA.
Sok D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, USA.; IAVI, New York, New York, USA.; IAVI, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, USA.
Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, USA.; IAVI, Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.
Hassell T; IAVI, New York, New York, USA.
Broly H; Ares Trading SA/Merck SA Switzerland, Aubonne, Switzerland.
Palinsky W; Ares Trading SA/Merck SA Switzerland, Aubonne, Switzerland.
Dupraz P; Ares Trading SA/Merck SA Switzerland, Aubonne, Switzerland.
Feinberg M; IAVI, New York, New York, USA.
Dey AK; IAVI, New York, New York, USA.
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2022 Feb; Vol. 119 (2), pp. 663-666. Date of Electronic Publication: 2021 Dec 10.
Typ publikacji :
Journal Article
MeSH Terms :
CHO Cells*
Antibodies, Monoclonal/*biosynthesis
Antibodies, Viral/*biosynthesis
COVID-19/*immunology
SARS-CoV-2/*immunology
Animals ; Antibodies, Monoclonal/immunology ; Antibodies, Viral/immunology ; Clinical Trials, Phase I as Topic/methods ; Clinical Trials, Phase I as Topic/standards ; Cricetulus ; Pandemics ; Transposases ; Viral Load
Czasopismo naukowe
Tytuł :
Knockout of caspase-7 gene improves the expression of recombinant protein in CHO cell line through the cell cycle arrest in G2/M phase.
Autorzy :
Safari F; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Meshkinfam Ave, Shiraz, Iran. .; Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. .
Akbari B; Department of Medical Biotechnology, School of Medical Sciences, Kermanshah University of Medical Sciences, Kermanshah, Iran.
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Źródło :
Biological research [Biol Res] 2022 Jan 11; Vol. 55 (1), pp. 2. Date of Electronic Publication: 2022 Jan 11.
Typ publikacji :
Journal Article
MeSH Terms :
CHO Cells*
Cell Cycle Checkpoints*
Caspase 7/*genetics
Recombinant Proteins/*biosynthesis
Animals ; Cell Division ; Cricetinae ; Cricetulus ; Gene Knockout Techniques ; Recombinant Proteins/genetics
Czasopismo naukowe
Tytuł :
Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis.
Autorzy :
Bryan L; National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland. .
Henry M; National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
Kelly RM; Eli Lilly and Company, LTC-North, 1200 Kentucky Avenue, Indianapolis, IN, 46225, USA.
Frye CC; Eli Lilly and Company, LTC-North, 1200 Kentucky Avenue, Indianapolis, IN, 46225, USA.
Osborne MD; Eli Lilly, Kinsale Limite, Cork, Ireland.
Clynes M; National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
Meleady P; National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.
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Źródło :
BMC biotechnology [BMC Biotechnol] 2021 Jul 23; Vol. 21 (1), pp. 43. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
CHO Cells/*chemistry
CHO Cells/*cytology
Proteins/*genetics
Animals ; CHO Cells/metabolism ; Cell Cycle ; Chromatography, Liquid ; Cricetinae ; Cricetulus ; Immunoglobulin G ; Phenotype ; Proteins/chemistry ; Proteins/metabolism ; Proteome/chemistry ; Proteome/genetics ; Proteome/metabolism ; Proteomics ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Rapid serum-free/suspension adaptation: Medium development using a definitive screening design for Chinese hamster ovary cells.
Autorzy :
Wu S; Graduate School for Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania, USA.
Rish AJ; Graduate School for Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania, USA.
Skomo A; Rangos School of Health Sciences, Duquesne University, Pittsburgh, Pennsylvania, USA.
Zhao Y; Graduate School for Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania, USA.
Drennen JK; Graduate School for Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania, USA.; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania, USA.
Anderson CA; Graduate School for Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania, USA.; Duquesne Center for Pharmaceutical Technology, Duquesne University, Pittsburgh, Pennsylvania, USA.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2021 Jul; Vol. 37 (4), pp. e3154. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CHO Cells*
Animals ; Cell Count/methods ; Cricetinae ; Cricetulus ; Culture Media/metabolism ; Culture Media/pharmacology ; Culture Media, Serum-Free/pharmacology
Czasopismo naukowe
Tytuł :
Improvement of the efficiency and quality in developing a new CHO host cell line.
Autorzy :
Huhn SC; Biologics Upstream Process Development, MRL, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Ou Y; Biologics Upstream Process Development, MRL, Merck & Co., Inc., Kenilworth, New Jersey, USA.; MRL Postdoctoral Research Program, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Tang X; Biologics Upstream Process Development, MRL, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Jiang B; Biologics Upstream Process Development, MRL, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Liu R; Biologics Upstream Process Development, MRL, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Lin H; Biologics Upstream Process Development, MRL, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Du Z; Biologics Upstream Process Development, MRL, Merck & Co., Inc., Kenilworth, New Jersey, USA.
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Źródło :
Biotechnology progress [Biotechnol Prog] 2021 Sep; Vol. 37 (5), pp. e3185. Date of Electronic Publication: 2021 Jun 26.
Typ publikacji :
Journal Article
MeSH Terms :
CHO Cells*
Gene Knockout Techniques*
Metabolic Engineering*
Recombinant Proteins*/genetics
Recombinant Proteins*/metabolism
Animals ; Cell Line ; Cricetinae ; Cricetulus ; Gene Editing ; Glutamate-Ammonia Ligase/genetics ; Transfection
Czasopismo naukowe
Tytuł :
Identification of Iranian BHK-21-C5 Cell Line by Two Steps Polymerase Chain Reaction.
Autorzy :
Ziyaeifar F; Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Soleimani S; Department of Biobank, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.; Department of Biobank, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.
Lotfi M; Department of Viral Vaccine Quality Control, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.
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Źródło :
Archives of Razi Institute [Arch Razi Inst] 2021 Jul; Vol. 76 (2), pp. 193-201. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CHO Cells*
Animals ; Cattle ; Cricetinae ; Cricetulus ; DNA Primers ; Iran ; Polymerase Chain Reaction/veterinary ; Sheep
Czasopismo naukowe
Tytuł :
A comprehensive comparison of mixing and mass transfer in shake flasks and their relationship with MAb productivity of CHO cells.
Autorzy :
Pérez-Rodriguez S; Unidad de Bioprocesos, Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Cd. Universitaria, Coyoacán, 04510, Ciudad de México, Mexico.
Reynoso-Cereceda GI; Unidad de Bioprocesos, Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Cd. Universitaria, Coyoacán, 04510, Ciudad de México, Mexico.
Valdez-Cruz NA; Unidad de Bioprocesos, Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Cd. Universitaria, Coyoacán, 04510, Ciudad de México, Mexico.
Trujillo-Roldán MA; Unidad de Bioprocesos, Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Cd. Universitaria, Coyoacán, 04510, Ciudad de México, Mexico. .
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Źródło :
Bioprocess and biosystems engineering [Bioprocess Biosyst Eng] 2022 Jun; Vol. 45 (6), pp. 1033-1045. Date of Electronic Publication: 2022 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Bioreactors*
Oxygen*/metabolism
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Recombinant Proteins
Czasopismo naukowe
Tytuł :
Modeling apoptosis resistance in CHO cells with CRISPR-mediated knockouts of Bak1, Bax, and Bok.
Autorzy :
MacDonald MA; ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Australia.
Barry C; ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Australia.
Groves T; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark.
Martínez VS; ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Australia.
Gray PP; ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Australia.
Baker K; Patheon by Thermo Fisher Scientific, Woolloongabba, Queensland, Australia.
Shave E; Patheon by Thermo Fisher Scientific, Woolloongabba, Queensland, Australia.
Mahler S; ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Australia.
Munro T; ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Australia.
Marcellin E; ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Australia.; Metabolomics Australia, The University of Queensland, Brisbane, Queensland, Australia.
Nielsen LK; ARC Training Centre for Biopharmaceutical Innovation, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Australia.; The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kgs. Lyngby, Denmark.
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2022 Jun; Vol. 119 (6), pp. 1380-1391. Date of Electronic Publication: 2022 Mar 06.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/genetics
Proto-Oncogene Proteins c-bcl-2*/genetics
Proto-Oncogene Proteins c-bcl-2*/metabolism
Animals ; Bayes Theorem ; CHO Cells ; Cricetinae ; Cricetulus ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł :
Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells.
Autorzy :
Barzadd MM; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Dept. of Protein Science, SE-106 91 Stockholm, Sweden.
Lundqvist M; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Dept. of Protein Science, SE-106 91 Stockholm, Sweden.
Harris C; Cell Culture & Fermentation Sciences, BioPharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Malm M; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Dept. of Protein Science, SE-106 91 Stockholm, Sweden.
Volk AL; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Dept. of Protein Science, SE-106 91 Stockholm, Sweden.
Thalén N; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Dept. of Protein Science, SE-106 91 Stockholm, Sweden.
Chotteau V; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Dept. of Industrial Biotechnology, SE-106 91 Stockholm, Sweden.
Grassi L; Cell Culture & Fermentation Sciences, BioPharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Smith A; Cell Culture & Fermentation Sciences, BioPharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Abadi ML; Cell Culture & Fermentation Sciences, BioPharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Lambiase G; Analytical Sciences, BioPharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK and Advanced Biomanufacturing Centre, Department of Chemical and Biological Engineering, University of Sheffield, Mappin Street, Sheffield, UK.
Gibson S; Cell Culture & Fermentation Sciences, BioPharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Hatton D; Cell Culture & Fermentation Sciences, BioPharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
Rockberg J; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Dept. of Protein Science, SE-106 91 Stockholm, Sweden. Electronic address: .
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Źródło :
New biotechnology [N Biotechnol] 2022 May 25; Vol. 68, pp. 68-76. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Bispecific*/metabolism
Animals ; Autophagy ; CHO Cells ; Cricetinae ; Cricetulus ; Systems Biology
Czasopismo naukowe
Tytuł :
Expression and characterization of a recombinant broadly-reactive monoclonal antibody against group 1 and 2 influenza viruses.
Autorzy :
Hu Z; Joint International Research Laboratory of Agriculture and Agri-Product Safety, The Ministry of Education of China, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, China; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China; Key Laboratory of Animal Infectious Diseases, School of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Huang Y; Key Laboratory of Animal Infectious Diseases, School of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Zhao J; Key Laboratory of Animal Infectious Diseases, School of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Hu J; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, China; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China; Key Laboratory of Animal Infectious Diseases, School of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Hu S; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, China; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China; Key Laboratory of Animal Infectious Diseases, School of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Liu X; Joint International Research Laboratory of Agriculture and Agri-Product Safety, The Ministry of Education of China, Yangzhou University, Yangzhou, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, China; Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China; Key Laboratory of Animal Infectious Diseases, School of Veterinary Medicine, Yangzhou University, Yangzhou, China. Electronic address: .
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Źródło :
Protein expression and purification [Protein Expr Purif] 2022 Apr; Vol. 192, pp. 106046. Date of Electronic Publication: 2022 Jan 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*immunology
Antibodies, Monoclonal/*pharmacology
Antibodies, Viral/*immunology
Antibodies, Viral/*pharmacology
Hemagglutinin Glycoproteins, Influenza Virus/*immunology
Orthomyxoviridae/*drug effects
Animals ; Antibodies, Monoclonal/genetics ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Viral/genetics ; Antibodies, Viral/isolation & purification ; CHO Cells ; Cricetinae ; Cricetulus ; Cross Reactions ; Gene Expression ; Hemagglutinin Glycoproteins, Influenza Virus/genetics ; Humans ; Influenza A Virus, H7N9 Subtype/genetics ; Influenza A Virus, H7N9 Subtype/immunology ; Influenza, Human/virology ; Mice ; Orthomyxoviridae/classification ; Orthomyxoviridae/immunology
Czasopismo naukowe
Tytuł :
Capillary-Mediated Vitrification: Preservation of mRNA at Elevated Temperatures.
Autorzy :
Renu S; Upkara, Inc, 1600 Huron Parkway Bldg 520, Rm 2390, Ann Arbor, Michigan, 48109, USA. .
Shank-Retzlaff M; Upkara, Inc, 1600 Huron Parkway Bldg 520, Rm 2390, Ann Arbor, Michigan, 48109, USA. .
Sharpe J; Upkara, Inc, 1600 Huron Parkway Bldg 520, Rm 2390, Ann Arbor, Michigan, 48109, USA.
Bronsart L; Upkara, Inc, 1600 Huron Parkway Bldg 520, Rm 2390, Ann Arbor, Michigan, 48109, USA.
Mohanty P; Upkara, Inc, 1600 Huron Parkway Bldg 520, Rm 2390, Ann Arbor, Michigan, 48109, USA.
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Źródło :
The AAPS journal [AAPS J] 2022 Jun 16; Vol. 24 (4), pp. 75. Date of Electronic Publication: 2022 Jun 16.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/prevention & control
Cytomegalovirus Infections*
Animals ; CHO Cells ; Cricetinae ; Freeze Drying ; Humans ; Pandemics ; RNA, Messenger ; Temperature ; Vitrification
Czasopismo naukowe
Tytuł :
Knockout of P-glycoprotein abolish the collateral sensitivity of CHO C5 multidrug resistant cells.
Autorzy :
Limniatis G; Institute of Parasitology, McGill University, Quebec, Canada.
Georges E; Institute of Parasitology, McGill University, Quebec, Canada. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jun 11; Vol. 608, pp. 23-29. Date of Electronic Publication: 2022 Mar 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP Binding Cassette Transporter, Subfamily B, Member 1*/genetics
ATP Binding Cassette Transporter, Subfamily B, Member 1*/metabolism
Drug Collateral Sensitivity*
ATP Binding Cassette Transporter, Subfamily B/genetics ; Animals ; CHO Cells ; Colchicine ; Cricetinae ; Doxorubicin/pharmacology ; Drug Resistance ; Verapamil
Czasopismo naukowe
Tytuł :
Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity.
Autorzy :
Mietzsch M; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Hull JA; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Makal VE; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Jimenez Ybargollin A; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Yu JC; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
McKissock K; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Bennett A; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Penzes J; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Lins-Austin B; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Yu Q; NRS-Institut Armand Frappier, Université du Québec, Laval, Quebec, Canada.
Chipman P; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Bhattacharya N; Biological Science Imaging Resource, Department of Biological Sciences, Florida State Universitygrid.255986.5, Tallahassee, Florida, USA.
Sousa D; Biological Science Imaging Resource, Department of Biological Sciences, Florida State Universitygrid.255986.5, Tallahassee, Florida, USA.
Strugatsky D; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Tijssen P; NRS-Institut Armand Frappier, Université du Québec, Laval, Quebec, Canada.
McKenna R; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
Agbandje-McKenna M; University of Floridagrid.15276.37, Department of Biochemistry & Molecular Biology, Gainesville, Florida, USA.
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Źródło :
Journal of virology [J Virol] 2022 Jun 08; Vol. 96 (11), pp. e0033522. Date of Electronic Publication: 2022 May 09.
Typ publikacji :
Journal Article
MeSH Terms :
Capsid*/metabolism
Dependovirus*/physiology
Animals ; CHO Cells ; Capsid Proteins/metabolism ; Cricetinae ; Cricetulus ; Cross Reactions ; Cryoelectron Microscopy ; Epitopes ; Genetic Vectors ; Humans ; Models, Molecular ; N-Acetylneuraminic Acid/metabolism
Czasopismo naukowe
Tytuł :
Mechanism of use-dependent Kv2 channel inhibition by RY785.
Autorzy :
Marquis MJ; Department of Physiology & Membrane Biology, University of California, Davis, Davis, CA.
Sack JT; Department of Physiology & Membrane Biology, University of California, Davis, Davis, CA.; Department of Anesthesiology and Pain Medicine, University of California, Davis, Davis, CA.
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Źródło :
The Journal of general physiology [J Gen Physiol] 2022 Jun 06; Vol. 154 (6). Date of Electronic Publication: 2022 Apr 18.
Typ publikacji :
Journal Article
MeSH Terms :
Ion Channel Gating*/physiology
Shab Potassium Channels*/metabolism
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Kinetics ; Rats
Czasopismo naukowe
Tytuł :
Recombinant antibodies aggregation and overcoming strategies in CHO cells.
Autorzy :
Xu T; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, 453003, Henan, China.; The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, 453002, Henan, China.
Zhang J; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, 453003, Henan, China.; School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
Wang T; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, 453003, Henan, China. .; School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, 453003, Henan, China. .
Wang X; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, 453003, Henan, China. .; School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, 453003, Henan, China. .
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Źródło :
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2022 Jun; Vol. 106 (11), pp. 3913-3922. Date of Electronic Publication: 2022 May 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Protein Processing, Post-Translational*
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Humans ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
QbD-guided pharmaceutical development of Pembrolizumab biosimilar candidate PSG-024 propelled to industry meeting primary requirements of comparability to Keytruda®.
Autorzy :
Jaffar-Aghaei M; Department of Research and Development, PersisGen Par Company, No. 125, Karaj Specific Express-way, Tehran 1399114913, Iran. Electronic address: .
Khanipour F; Department of Research and Development, PersisGen Par Company, No. 125, Karaj Specific Express-way, Tehran 1399114913, Iran.
Maghsoudi A; Department of Research and Development, PersisGen Par Company, No. 125, Karaj Specific Express-way, Tehran 1399114913, Iran; Department of Biopharmaceuticals Manufacturing, PersisGen Par Company, Tehran, Iran.
Sarvestani R; Department of Research and Development, PersisGen Par Company, No. 125, Karaj Specific Express-way, Tehran 1399114913, Iran.
Mohammadian M; Department of Research and Development, PersisGen Par Company, No. 125, Karaj Specific Express-way, Tehran 1399114913, Iran.
Maleki M; Department of Research and Development, PersisGen Par Company, No. 125, Karaj Specific Express-way, Tehran 1399114913, Iran; Department of Biopharmaceuticals Manufacturing, PersisGen Par Company, Tehran, Iran.
Havasi F; Department of Research and Development, PersisGen Par Company, No. 125, Karaj Specific Express-way, Tehran 1399114913, Iran.
Rahmani H; Department of Research and Development, PersisGen Par Company, No. 125, Karaj Specific Express-way, Tehran 1399114913, Iran.
Karagah AH; Department of Research and Development, PersisGen Par Company, No. 125, Karaj Specific Express-way, Tehran 1399114913, Iran; Department of Biopharmaceuticals Manufacturing, PersisGen Par Company, Tehran, Iran.
Kazemali MR; Department of Biologicals and Vaccines Manufacturing, Nivad PharMed Salamat Company, No. 56, Dr. Habibollah Street, Tehran 1455714181, Iran. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2022 Jun 01; Vol. 173, pp. 106171. Date of Electronic Publication: 2022 Apr 01.
Typ publikacji :
Journal Article
MeSH Terms :
Biosimilar Pharmaceuticals*/pharmacology
Biosimilar Pharmaceuticals*/therapeutic use
Animals ; Antibodies, Monoclonal, Humanized ; CHO Cells ; Cricetinae ; Cricetulus ; Drug Design ; Humans ; Pharmaceutical Preparations
Czasopismo naukowe
Tytuł :
High-density adherent culture of CHO cells using rolled scaffold bioreactor.
Autorzy :
YekrangSafakar A; Division of Electrical and Computer Engineering, Louisiana State University, Baton Rouge, Louisiana, USA.
Mehrnezhad A; Division of Electrical and Computer Engineering, Louisiana State University, Baton Rouge, Louisiana, USA.
Wu T; Division of Electrical and Computer Engineering, Louisiana State University, Baton Rouge, Louisiana, USA.
Park K; Division of Electrical and Computer Engineering, Louisiana State University, Baton Rouge, Louisiana, USA.
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2022 Jun; Vol. 119 (6), pp. 1498-1508. Date of Electronic Publication: 2022 Apr 02.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Products*
Bioreactors*
Animals ; CHO Cells ; Cell Culture Techniques ; Cricetinae ; Cricetulus
Czasopismo naukowe
Tytuł :
Fast clearance of platelets in a commonly used mouse model for GPIbα is impeded by an anti-GPIbβ antibody derivative.
Autorzy :
Chen W; Aflac Cancer and Blood Disorders Center, Departments of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine Atlanta, Atlanta, Georgia, USA.
Wilson MS; Aflac Cancer and Blood Disorders Center, Departments of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine Atlanta, Atlanta, Georgia, USA.
Wang Y; Aflac Cancer and Blood Disorders Center, Departments of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine Atlanta, Atlanta, Georgia, USA.
Bergmeier W; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Lanza F; Université de Strasbourg, INSERM, BPPS UMR-S1255, Strasbourg, France.
Li R; Aflac Cancer and Blood Disorders Center, Departments of Pediatrics, Children's Healthcare of Atlanta, Emory University School of Medicine Atlanta, Atlanta, Georgia, USA.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2022 Jun; Vol. 20 (6), pp. 1451-1463. Date of Electronic Publication: 2022 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets*/metabolism
Thrombocytopenia*/metabolism
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Disease Models, Animal ; Humans ; Mice ; Mice, Transgenic ; Platelet Glycoprotein GPIb-IX Complex/metabolism
Czasopismo naukowe
Tytuł :
A multiauxotrophic CHO cell line for the rapid isolation of producers of diverse or high levels of recombinant proteins.
Autorzy :
Zhang Q; Department of Biological Sciences, Columbia University, New York, New York, USA.
Jiang B; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Nelson L; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Huhn S; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Du Z; Merck & Co., Inc., Kenilworth, New Jersey, USA.
Chasin LA; Department of Biological Sciences, Columbia University, New York, New York, USA.
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2022 Jun; Vol. 119 (6), pp. 1392-1404. Date of Electronic Publication: 2022 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Engineering*
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Recombinant Proteins/metabolism ; Transfection
Czasopismo naukowe

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