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Tytuł :
Role of Choline in Ocular Diseases.
Autorzy :
Hwang JS; Department of Ophthalmology, Hallym University Medical Center, Hallym University College of Medicine, Seoul 07442, Korea.
Shin YJ; Department of Ophthalmology, Hallym University Medical Center, Hallym University College of Medicine, Seoul 07442, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 29; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Choline/*physiology
Eye Diseases/*metabolism
Acetylcholine/biosynthesis ; Acetylcholine/physiology ; Animals ; Choline Deficiency/complications ; Choline Deficiency/physiopathology ; Diabetic Retinopathy/physiopathology ; Dry Eye Syndromes/drug therapy ; Dry Eye Syndromes/metabolism ; Dry Eye Syndromes/physiopathology ; Eye Diseases/etiology ; Eye Diseases/physiopathology ; Eye Pain/physiopathology ; Glaucoma/physiopathology ; Glycerylphosphorylcholine/therapeutic use ; Humans ; Lacrimal Apparatus/innervation ; Lacrimal Apparatus/metabolism ; Lens, Crystalline/metabolism ; Nociception/physiology ; Optic Nerve/metabolism ; Parasympathetic Nervous System/physiopathology ; Phosphatidylcholines/biosynthesis ; Phospholipids/metabolism ; Receptors, Nicotinic/physiology ; Retina/growth & development ; Retina/metabolism ; Retinal Vessels/metabolism ; Tears/metabolism
Czasopismo naukowe
Tytuł :
Choline Acetyltransferase Induces the Functional Regeneration of the Salivary Gland in Aging SAMP1/Kl -/- Mice.
Autorzy :
Toan NK; Department of Pathology, School of Dentistry, Chosun University, Gwangju 61452, Korea.
Tai NC; Department of Pathology, School of Dentistry, Chosun University, Gwangju 61452, Korea.
Kim SA; Department of Biochemistry, School of Oriental Medicine, Dongguk University, Gyeongju 38066, Korea.
Ahn SG; Department of Pathology, School of Dentistry, Chosun University, Gwangju 61452, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 02; Vol. 22 (1). Date of Electronic Publication: 2021 Jan 02.
Typ publikacji :
Journal Article
MeSH Terms :
Acetylcholine/*metabolism
Aging/*metabolism
Choline O-Acetyltransferase/*metabolism
Glucuronidase/*metabolism
Membrane Proteins/*metabolism
Nuclear Proteins/*metabolism
Salivary Glands/*metabolism
Acetyl Coenzyme A/metabolism ; Acetylcholine/genetics ; Aging/genetics ; Animals ; Cell Line ; Choline/metabolism ; Choline O-Acetyltransferase/genetics ; Down-Regulation ; Gene Expression Regulation/genetics ; Gene Knockdown Techniques ; Glucuronidase/genetics ; Humans ; Membrane Proteins/genetics ; Metabolomics ; Mice ; Mice, Knockout ; Nuclear Proteins/genetics ; Salivary Glands/enzymology ; Up-Regulation ; Zonula Occludens-1 Protein/genetics ; Zonula Occludens-1 Protein/metabolism ; alpha-Amylases/genetics ; alpha-Amylases/metabolism
Czasopismo naukowe
Tytuł :
Genetic diseases of the Kennedy pathways for membrane synthesis.
Autorzy :
Tavasoli M; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.
Lahire S; University of Reims Champagne-Ardenne, Reims, France.
Reid T; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.
Brodovsky M; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.
McMaster CR; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Dec 18; Vol. 295 (51), pp. 17877-17886.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cytidine Diphosphate/*analogs & derivatives
Cytidine Diphosphate Choline/*metabolism
Ethanolamines/*metabolism
Animals ; Choline Kinase/chemistry ; Choline Kinase/genetics ; Choline-Phosphate Cytidylyltransferase/chemistry ; Choline-Phosphate Cytidylyltransferase/genetics ; Cytidine Diphosphate/metabolism ; Genetic Association Studies ; Humans ; Muscular Dystrophies/congenital ; Muscular Dystrophies/genetics ; Muscular Dystrophies/pathology ; Osteochondrodysplasias/congenital ; Osteochondrodysplasias/genetics ; Osteochondrodysplasias/pathology ; Polymorphism, Single Nucleotide
SCR Disease Name :
Strudwick syndrome
Czasopismo naukowe
Tytuł :
Esomeprazole reduces sperm motility index by targeting the spermic cholinergic machinery: A mechanistic study for the association between use of proton pump inhibitors and reduced sperm motility index.
Autorzy :
Kumar A; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. Electronic address: .
Kumar R; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
Flanagan J; ANOVA, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.
Långström B; Department of Chemistry, Uppsala University, Uppsala, Sweden.
Björndahl L; ANOVA, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden; Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
Darreh-Shori T; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2020 Dec; Vol. 182, pp. 114212. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Choline O-Acetyltransferase/*metabolism
Esomeprazole/*metabolism
Esomeprazole/*pharmacology
Proton Pump Inhibitors/*metabolism
Proton Pump Inhibitors/*pharmacology
Sperm Motility/*drug effects
Adult ; Choline/metabolism ; Choline/pharmacology ; Choline O-Acetyltransferase/chemistry ; Dose-Response Relationship, Drug ; Humans ; Male ; Protein Binding/drug effects ; Protein Binding/physiology ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Sperm Motility/physiology ; Spermatozoa/drug effects ; Spermatozoa/metabolism
Czasopismo naukowe
Tytuł :
Targeting ferroptosis alleviates methionine-choline deficient (MCD)-diet induced NASH by suppressing liver lipotoxicity.
Autorzy :
Li X; Department of Endocrinology of the Fifth People's Hospital of Shanghai and the Molecular and Cell Biology Lab of the Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Wang TX; Department of Endocrinology of the Fifth People's Hospital of Shanghai and the Molecular and Cell Biology Lab of the Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Huang X; Department of Endocrinology of the Fifth People's Hospital of Shanghai and the Molecular and Cell Biology Lab of the Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Li Y; Department of Endocrinology of the Fifth People's Hospital of Shanghai and the Molecular and Cell Biology Lab of the Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Sun T; Department of Endocrinology of the Fifth People's Hospital of Shanghai and the Molecular and Cell Biology Lab of the Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Zang S; Department of Endocrinology of the Fifth People's Hospital of Shanghai and the Molecular and Cell Biology Lab of the Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Guan KL; Department of Pharmacology and Moores Cancer Center, University of California San Diego, CA, La Jolla, USA.
Xiong Y; Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Liu J; Department of Endocrinology of the Fifth People's Hospital of Shanghai and the Molecular and Cell Biology Lab of the Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Yuan HX; Department of Endocrinology of the Fifth People's Hospital of Shanghai and the Molecular and Cell Biology Lab of the Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
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Źródło :
Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2020 Jun; Vol. 40 (6), pp. 1378-1394. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Choline Deficiency*
Ferroptosis*
Non-alcoholic Fatty Liver Disease*/drug therapy
Non-alcoholic Fatty Liver Disease*/etiology
Animals ; Choline ; Diet ; Liver ; Methionine ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Deficiency in Tissue Non-Specific Alkaline Phosphatase Leads to Steatohepatitis in Mice Fed a High Fat Diet Similar to That Produced by a Methionine and Choline Deficient Diet.
Autorzy :
Gámez-Belmonte R; Department of Pharmacology, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, University of Granada, 18071 Granada, Spain.
Tena-Garitaonaindia M; Department of Biochemistry and Molecular Biology 2, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, Instituto de Nutrición y Tecnología de los Alimentos José Mataix, University of Granada, 18071 Granada, Spain.
Hernández-Chirlaque C; Department of Biochemistry and Molecular Biology 2, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, Instituto de Nutrición y Tecnología de los Alimentos José Mataix, University of Granada, 18071 Granada, Spain.
Córdova S; Department of Biochemistry and Molecular Biology 2, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, Instituto de Nutrición y Tecnología de los Alimentos José Mataix, University of Granada, 18071 Granada, Spain.
Ceacero-Heras D; Department of Biochemistry and Molecular Biology 2, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, Instituto de Nutrición y Tecnología de los Alimentos José Mataix, University of Granada, 18071 Granada, Spain.
de Medina FS; Department of Pharmacology, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, University of Granada, 18071 Granada, Spain.
Martínez-Augustin O; Department of Biochemistry and Molecular Biology 2, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, Instituto de Nutrición y Tecnología de los Alimentos José Mataix, University of Granada, 18071 Granada, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 23; Vol. 22 (1). Date of Electronic Publication: 2020 Dec 23.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaline Phosphatase/*deficiency
Choline/*metabolism
Diet, High-Fat/*adverse effects
Fatty Liver/*etiology
Fatty Liver/*metabolism
Methionine/*metabolism
Alkaline Phosphatase/metabolism ; Alleles ; Animals ; Choline Deficiency ; Diet ; Disease Models, Animal ; Enzyme Activation ; Methionine/deficiency ; Mice ; Mice, Knockout ; Mitogen-Activated Protein Kinases/metabolism ; PPAR alpha/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
The pharmacodynamic and differential gene expression analysis of PPAR α/δ agonist GFT505 in CDAHFD-induced NASH model.
Autorzy :
Liu L; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Collaborative Innovation Center for Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Liu C; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Collaborative Innovation Center for Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Zhao M; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Zhang Q; Collaborative Innovation Center for Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.; Guangdong Zhongsheng Pharmaceutical Co., Ltd., Guangdong, China.
Lu Y; Collaborative Innovation Center for Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Liu P; Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu, Sichuan, China.
Yang H; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Yang J; Collaborative Innovation Center for Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.; Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu, Sichuan, China.
Chen X; Guangdong Zhongsheng Pharmaceutical Co., Ltd., Guangdong, China.; Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu, Sichuan, China.
Yao Y; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.; Collaborative Innovation Center for Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
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Źródło :
PloS one [PLoS One] 2020 Dec 16; Vol. 15 (12), pp. e0243911. Date of Electronic Publication: 2020 Dec 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Choline Deficiency/*genetics
Non-alcoholic Fatty Liver Disease/*genetics
PPAR alpha/*genetics
Receptors, Cytoplasmic and Nuclear/*genetics
Amino Acids/metabolism ; Animals ; Chalcones/pharmacology ; Choline/genetics ; Choline Deficiency/pathology ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Gene Expression Regulation/genetics ; Humans ; Mice ; Non-alcoholic Fatty Liver Disease/drug therapy ; Non-alcoholic Fatty Liver Disease/pathology ; PPAR alpha/agonists ; Propionates/pharmacology ; Receptors, Cytoplasmic and Nuclear/agonists ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Engineering substrate and energy metabolism for living cell production of cytidine-5'-diphosphocholine.
Autorzy :
Ren Y; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Liu Q; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Liu H; China Resources Angde Biotech Pharmaceutical Co, Ltd, Liaocheng, China.
Zhou X; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.; China Resources Angde Biotech Pharmaceutical Co, Ltd, Liaocheng, China.
Zhang Y; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.; Shanghai Collaborative Innovation Center for Biomanufacturing, Shanghai, China.
Cai M; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
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Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2020 May; Vol. 117 (5), pp. 1426-1435. Date of Electronic Publication: 2020 Feb 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytidine Diphosphate Choline*/analysis
Cytidine Diphosphate Choline*/biosynthesis
Saccharomycetales*/genetics
Saccharomycetales*/metabolism
Metabolic Engineering/*methods
Adenosine Triphosphate/metabolism ; Choline/metabolism ; Energy Metabolism
SCR Organism :
Komagataella pastoris
Czasopismo naukowe
Tytuł :
A Systematic Review of the Dietary Choline Impact on Cognition from a Psychobiological Approach: Insights from Animal Studies.
Autorzy :
Gámiz F; Department of Psychobiology, Institute of Neurosciences, Center for Biomedical Research (CIBM), University of Granada, 18010 Granada, Spain.
Gallo M; Department of Psychobiology, Institute of Neurosciences, Center for Biomedical Research (CIBM), University of Granada, 18010 Granada, Spain.
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Źródło :
Nutrients [Nutrients] 2021 Jun 08; Vol. 13 (6). Date of Electronic Publication: 2021 Jun 08.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Choline/*pharmacology
Cognition/*drug effects
Diet/*psychology
Animals ; Anxiety/psychology ; Authorship ; Behavior, Animal/drug effects ; Choline/administration & dosage ; Emotions/drug effects ; Publications
Czasopismo naukowe
Tytuł :
Recent advances in green solvents for lignocellulosic biomass pretreatment: Potential of choline chloride (ChCl) based solvents.
Autorzy :
Yiin CL; Department of Chemical Engineering and Energy Sustainability, Faculty of Engineering, Universiti Malaysia Sarawak (UNIMAS), Kota Samarahan 94300, Sarawak, Malaysia. Electronic address: .
Yap KL; Department of Chemical Engineering and Energy Sustainability, Faculty of Engineering, Universiti Malaysia Sarawak (UNIMAS), Kota Samarahan 94300, Sarawak, Malaysia. Electronic address: .
Ku AZE; Department of Chemical Engineering and Energy Sustainability, Faculty of Engineering, Universiti Malaysia Sarawak (UNIMAS), Kota Samarahan 94300, Sarawak, Malaysia. Electronic address: .
Chin BLF; Department of Chemical Engineering, Faculty of Engineering and Science, Sarawak Campus, Curtin University Malaysia, Miri 98009, Sarawak, Malaysia. Electronic address: .
Lock SSM; CO(2) Research Center (CO2RES), Department of Chemical Engineering, Universiti Teknologi PETRONAS, 32610 Seri Iskandar, Malaysia. Electronic address: .
Cheah KW; Energy and Environment Institute, University of Hull, Cottingham Road, Kingston upon Hull HU6 7RX, United Kingdom. Electronic address: .
Loy ACM; Chemical Engineering Department, Monash University, 3180, Victoria, Australia. Electronic address: .
Chan YH; PETRONAS Research Sdn. Bhd. (PRSB), Lot 3288 & 3289, Off Jalan Ayer Itam, Kawasan Institusi Bangi, 43000 Kajang, Selangor, Malaysia. Electronic address: .
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Źródło :
Bioresource technology [Bioresour Technol] 2021 Aug; Vol. 333, pp. 125195. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Choline*
Lignin*
Biomass ; Solvents
Czasopismo naukowe
Tytuł :
Buttermilk: an important source of lipid soluble forms of choline that influences the immune system development in Sprague-Dawley rat offspring.
Autorzy :
Azarcoya-Barrera J; Department of Agricultural, Food and Nutritional Science, Center for Health Research Innovation, University of Alberta, 4-002G Li Ka Shing, Edmonton, AB, T6G 2E1, Canada.
Field CJ; Department of Agricultural, Food and Nutritional Science, Center for Health Research Innovation, University of Alberta, 4-002G Li Ka Shing, Edmonton, AB, T6G 2E1, Canada.
Goruk S; Department of Agricultural, Food and Nutritional Science, Center for Health Research Innovation, University of Alberta, 4-002G Li Ka Shing, Edmonton, AB, T6G 2E1, Canada.
Makarowski A; Department of Agricultural, Food and Nutritional Science, Center for Health Research Innovation, University of Alberta, 4-002G Li Ka Shing, Edmonton, AB, T6G 2E1, Canada.
Curtis JM; Department of Agricultural, Food and Nutritional Science, Center for Health Research Innovation, University of Alberta, 4-002G Li Ka Shing, Edmonton, AB, T6G 2E1, Canada.
Pouliot Y; STELA Dairy Research Center, Institute of Nutrition and Functional Foods (INAF), Université Laval, Québec, Canada.
Jacobs RL; Department of Agricultural, Food and Nutritional Science, Center for Health Research Innovation, University of Alberta, 4-002G Li Ka Shing, Edmonton, AB, T6G 2E1, Canada.
Richard C; Department of Agricultural, Food and Nutritional Science, Center for Health Research Innovation, University of Alberta, 4-002G Li Ka Shing, Edmonton, AB, T6G 2E1, Canada. .
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Źródło :
European journal of nutrition [Eur J Nutr] 2021 Aug; Vol. 60 (5), pp. 2807-2818. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :
Journal Article
MeSH Terms :
Buttermilk*
Choline*
Animals ; Female ; Humans ; Immune System ; Lactation ; Lipids ; Maternal Nutritional Physiological Phenomena ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets.
Autorzy :
Liu R; Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, China; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China. Electronic address: .
Lee JH; Department of Health Sciences, The Graduate School of Dong-A University, Busan, 49315, Republic of Korea; Department of Biological Sciences, Dong-A University, Busan 49315, Republic of Korea.
Li J; The Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu, Sichuan, 610051, China.
Yu R; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, Shandong 266003, China.
Tan L; The Proteomics and Metabolomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
Xia Y; Department of Neuro-Oncology and Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Zheng Y; Department of Neuro-Oncology and Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Bian XL; The Affiliated Hospital of Qingdao University, Qingdao Cancer Institute, Qingdao, Shandong 266071, China.
Lorenzi PL; The Proteomics and Metabolomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
Chen Q; Stomatology Hospital, School of Stomatology, Cancer Center, Zhejiang University School of Medicine, and Key Laboratory of Oral Biomedical Research of Zhejiang Province, Clinical Research Center of Oral Diseases of Zhejiang Province, Hangzhou, 310006, Zhejiang, China. Electronic address: .
Lu Z; Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, 310029, China; Zhejiang University Cancer Center, Hangzhou, 310029, China. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2021 Jul 01; Vol. 81 (13), pp. 2722-2735.e9. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipolysis*
Choline Kinase/*metabolism
Glioblastoma/*enzymology
Lipid Droplets/*enzymology
Neoplasm Proteins/*metabolism
Protein Kinases/*metabolism
Acetylation ; Cell Line, Tumor ; Choline Kinase/genetics ; Glioblastoma/genetics ; Humans ; Neoplasm Proteins/genetics ; Protein Kinases/genetics
Czasopismo naukowe
Tytuł :
Mass Spectrometric Enzyme Histochemistry for Choline Acetyltransferase Reveals De Novo Acetylcholine Synthesis in Rodent Brain and Spinal Cord.
Autorzy :
Takeo E; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Sugiura Y; Department of Biochemistry, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Ohnishi Y; Department of Neurosurgery, Graduate school of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Kishima H; Department of Neurosurgery, Graduate school of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Fukusaki E; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
Shimma S; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.
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Źródło :
ACS chemical neuroscience [ACS Chem Neurosci] 2021 Jun 16; Vol. 12 (12), pp. 2079-2087. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetylcholine*
Choline O-Acetyltransferase*/metabolism
Animals ; Brain/diagnostic imaging ; Brain/metabolism ; Mass Spectrometry ; Mice ; Rodentia/metabolism ; Spinal Cord/metabolism
Czasopismo naukowe
Tytuł :
Maternal nutrients and effects of gestational COVID-19 infection on fetal brain development.
Autorzy :
Hoffman MC; Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Colorado Denver School of Medicine, Mail Stop F-546, Anschutz Medical Center, Aurora, CO, 80045, USA; Department of Psychiatry, University of Colorado Denver School of Medicine, Mail Stop F-546, Anschutz Medical Center, Aurora, CO, 80045, USA. Electronic address: .
Freedman R; Department of Psychiatry, University of Colorado Denver School of Medicine, Mail Stop F-546, Anschutz Medical Center, Aurora, CO, 80045, USA. Electronic address: .
Law AJ; Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Colorado Denver School of Medicine, Mail Stop F-546, Anschutz Medical Center, Aurora, CO, 80045, USA; Department of Psychiatry, University of Colorado Denver School of Medicine, Mail Stop F-546, Anschutz Medical Center, Aurora, CO, 80045, USA; Department of Cell and Developmental Biology, University of Colorado Denver School of Medicine, Mail Stop F-546, Anschutz Medical Center, Aurora, CO, 80045, USA; Department of Medicine, University of Colorado Denver School of Medicine, Mail Stop F-546, Anschutz Medical Center, Aurora, CO, 80045, USA. Electronic address: .
Clark AM; Department of Nutrition and Dietetics, Campus Box 93, University of Northern Colorado, Greeley, CO, 80639, USA. Electronic address: .
Hunter SK; Department of Psychiatry, University of Colorado Denver School of Medicine, Mail Stop F-546, Anschutz Medical Center, Aurora, CO, 80045, USA. Electronic address: .
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Źródło :
Clinical nutrition ESPEN [Clin Nutr ESPEN] 2021 Jun; Vol. 43, pp. 1-8. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Brain*/drug effects
Fetal Development*/drug effects
Mothers*
Nutritional Status*
COVID-19/*complications
Choline/*therapeutic use
Pregnancy Complications, Infectious/*virology
Animals ; COVID-19/metabolism ; COVID-19/virology ; Child Development/drug effects ; Choline/pharmacology ; Developmental Disabilities/etiology ; Developmental Disabilities/prevention & control ; Dietary Supplements ; Fatty Acids, Omega-3/pharmacology ; Fatty Acids, Omega-3/therapeutic use ; Female ; Fetus/drug effects ; Folic Acid/pharmacology ; Folic Acid/therapeutic use ; Humans ; Infant ; Inflammation/complications ; Inflammation/metabolism ; Nutritional Requirements ; Pandemics ; Placenta/metabolism ; Pregnancy ; Pregnancy Complications, Infectious/metabolism ; SARS-CoV-2 ; Vitamin D/pharmacology ; Vitamin D/therapeutic use
Czasopismo naukowe
Tytuł :
Application of choline-based deep eutectic solvent for the extraction of crude-oil contaminated soils.
Autorzy :
Duan M; School of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu, People's Republic of China.
Luo M; School of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu, People's Republic of China.
Yang Z; School of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu, People's Republic of China.
Xiong Y; School of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu, People's Republic of China.
Shi P; School of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu, People's Republic of China.
Fang S; School of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu, People's Republic of China.; Industrial Hazardous Waste Disposal and Resource Utilization Research Institute, Southwest Petroleum University, Chengdu, People's Republic of China.
Qin S; Engineering Technology Research Institute of Petrochina Southwest oil and Gasfield Company, Chengdu, People's Republic of China.
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Źródło :
Environmental technology [Environ Technol] 2021 Jul; Vol. 42 (18), pp. 2896-2901. Date of Electronic Publication: 2020 Jan 29.
Typ publikacji :
Journal Article
MeSH Terms :
Choline*
Petroleum*
Plant Extracts ; Soil ; Solvents
Czasopismo naukowe
Tytuł :
Molecular dynamics simulations of choline chloride and phenyl propionic acid deep eutectic solvents: Investigation of structural and dynamics properties.
Autorzy :
Bonab PJ; Department of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, Tabriz, Iran; Molecular Simulation Laboratory (MSL), Azarbaijan Shahid Madani University, Tabriz, Iran; Molecular Science and Engineering Research Group (MSERG), Azarbaijan Shahid Madani University, Tabriz, Iran.
Esrafili MD; Department of Chemistry, Faculty of Basic Sciences, University of Maragheh, Maragheh, Iran.
Ebrahimzadeh AR; Molecular Simulation Laboratory (MSL), Azarbaijan Shahid Madani University, Tabriz, Iran; Molecular Science and Engineering Research Group (MSERG), Azarbaijan Shahid Madani University, Tabriz, Iran; Department of Physics, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, Tabriz, Iran.
Sardroodi JJ; Department of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University, Tabriz, Iran; Molecular Simulation Laboratory (MSL), Azarbaijan Shahid Madani University, Tabriz, Iran; Molecular Science and Engineering Research Group (MSERG), Azarbaijan Shahid Madani University, Tabriz, Iran. Electronic address: .
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Źródło :
Journal of molecular graphics & modelling [J Mol Graph Model] 2021 Jul; Vol. 106, pp. 107908. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Choline*
Molecular Dynamics Simulation*
Propionates ; Solvents
Czasopismo naukowe
Tytuł :
Assessment of the viability and treatment response of bone metastases in patients with metastatic castration-resistant prostate cancer using choline PET/CT.
Autorzy :
Kitajima K; Department of Radiology.
Yamamoto S; Department of Urology, Hyogo College of Medicine, Hyogo, Japan.
Kawanaka Y; Department of Radiology.
Komoto H; Department of Radiology.
Shimatani K; Department of Urology, Hyogo College of Medicine, Hyogo, Japan.
Hanasaki T; Department of Urology, Hyogo College of Medicine, Hyogo, Japan.
Taguchi M; Department of Urology, Hyogo College of Medicine, Hyogo, Japan.
Nagasawa S; Department of Urology, Hyogo College of Medicine, Hyogo, Japan.
Yamada Y; Department of Urology, Hyogo College of Medicine, Hyogo, Japan.
Kanematsu A; Department of Urology, Hyogo College of Medicine, Hyogo, Japan.
Yamakado K; Department of Radiology.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Jun 11; Vol. 100 (23), pp. e26206.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Neoplasms/*secondary
Choline/*pharmacology
Positron Emission Tomography Computed Tomography/*standards
Prostatic Neoplasms, Castration-Resistant/*diagnostic imaging
Adult ; Aged ; Aged, 80 and over ; Bone Neoplasms/diagnostic imaging ; Bone Neoplasms/etiology ; Choline/therapeutic use ; Humans ; Male ; Middle Aged ; Neoplasm Metastasis/diagnostic imaging ; Neoplasm Metastasis/physiopathology ; Positron Emission Tomography Computed Tomography/instrumentation ; Positron Emission Tomography Computed Tomography/methods ; Radiopharmaceuticals/pharmacology ; Radiopharmaceuticals/therapeutic use
Czasopismo naukowe
Tytuł :
Hepatocyte-specific deletion of Nlrp6 in mice exacerbates the development of non-alcoholic steatohepatitis.
Autorzy :
Huang C; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Liu Q; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Tang Q; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Jing X; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Wu T; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Zhang J; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Zhang G; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Zhou J; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Zhang Z; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Zhao Y; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Huang H; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Xia Y; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Yan J; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Xiao J; Clinical Research Institute, First Affiliated Hospital of Jinan University, Guangzhou 510632, China. Electronic address: .
Li Y; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China. Electronic address: .
He J; Department of Pharmacy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; Laboratory of Clinical Pharmacy and Adverse Drug Reaction, National Clinical Research Center for Geriatrics,West China Hospital, Sichuan University, Chengdu, Sichuan Province, China. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2021 Jun; Vol. 169, pp. 110-121. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Choline Deficiency*
Non-alcoholic Fatty Liver Disease*/genetics
Animals ; Disease Models, Animal ; Hepatocytes ; Humans ; Intracellular Signaling Peptides and Proteins ; Liver ; Methionine ; Mice ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Tytuł :
Effects of aging on the cholinergic innervation of the rat ventral tegmental area: A stereological study.
Autorzy :
Pereira PA; Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal; Center for Health Technology and Services Research (CINTESIS), Rua Dr. Plácido da Costa, 4200-450 Porto, Portugal. Electronic address: .
Coelho J; Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal.
Silva A; Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal; Center for Health Technology and Services Research (CINTESIS), Rua Dr. Plácido da Costa, 4200-450 Porto, Portugal.
Madeira MD; Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal; Center for Health Technology and Services Research (CINTESIS), Rua Dr. Plácido da Costa, 4200-450 Porto, Portugal. Electronic address: .
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Źródło :
Experimental gerontology [Exp Gerontol] 2021 Jun; Vol. 148, pp. 111298. Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Choline O-Acetyltransferase*/metabolism
Ventral Tegmental Area*/metabolism
Aging ; Animals ; Cholinergic Agents ; Dopamine ; Rats
Czasopismo naukowe
Tytuł :
Arachidonate 12S-lipoxygenase of platelet-type in hepatic stellate cells of methionine and choline-deficient diet-fed mice.
Autorzy :
Mori Y; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Kawakami Y; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Kanzaki K; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.; Department of Clinical Nutrition, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare, 288 Matsushima, Kurashiki, Okayama 701-0193, Japan.
Otsuki A; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Kimura Y; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Kanji H; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Tanaka R; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Tsukayama I; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Hojo N; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Suzuki-Yamamoto T; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Kawakami T; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
Takahashi Y; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan.
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Źródło :
Journal of biochemistry [J Biochem] 2020 Nov 01; Vol. 168 (5), pp. 455-463.
Typ publikacji :
Journal Article
MeSH Terms :
Arachidonate 12-Lipoxygenase/*metabolism
Choline/*metabolism
Diet/*adverse effects
Hepatic Stellate Cells/*enzymology
Liver/*enzymology
Methionine/*deficiency
Non-alcoholic Fatty Liver Disease/*pathology
Animals ; Arachidonate 12-Lipoxygenase/genetics ; Choline Deficiency/metabolism ; Disease Models, Animal ; Isoenzymes ; Male ; Mice ; Mice, Inbred C57BL ; Non-alcoholic Fatty Liver Disease/enzymology ; Non-alcoholic Fatty Liver Disease/etiology
Czasopismo naukowe

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