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Wyszukujesz frazę ""COMPUTER simulation"" wg kryterium: Temat


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Tytuł:
Anti-Obesity Therapeutic Targets Studied In Silico and In Vivo: A Systematic Review.
Autorzy:
de Medeiros WF; Nutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-900, Brazil.
Gomes AFT; Nutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-900, Brazil.
Aguiar AJFC; Biochemistry and Molecular Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.
de Queiroz JLC; Biochemistry and Molecular Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.
Bezerra IWL; Nutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-900, Brazil.; Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-900, Brazil.
da Silva-Maia JK; Nutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-900, Brazil.; Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-900, Brazil.
Piuvezam G; Public Health Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-400, Brazil.; Public Health Department, Federal University of Rio Grande do Norte, Natal 59078-900, Brazil.
Morais AHA; Nutrition Postgraduate Program, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-900, Brazil.; Biochemistry and Molecular Biology Postgraduate Program, Biosciences Center, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.; Department of Nutrition, Center for Health Sciences, Federal University of Rio Grande do Norte, Natal 59078-900, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 25; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 25.
Typ publikacji:
Journal Article; Systematic Review; Review
MeSH Terms:
Obesity*/drug therapy
Obesity*/metabolism
Computer Simulation*
Humans ; Animals ; Molecular Docking Simulation ; Anti-Obesity Agents/pharmacology ; Anti-Obesity Agents/therapeutic use ; Lipase/metabolism ; Lipase/antagonists & inhibitors ; Molecular Targeted Therapy/methods
Czasopismo naukowe
Tytuł:
Systematic in-silico evaluation of fibrosis effects on re-entrant wave dynamics in atrial tissue.
Autorzy:
Masè M; Laboratory of Biophysics and Translational Cardiology, Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, Via Sommarive 18, 38123, Povo, Trento, Italy. .
Cristoforetti A; Laboratory of Biophysics and Translational Cardiology, Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, Via Sommarive 18, 38123, Povo, Trento, Italy.
Pelloni S; Laboratory of Biophysics and Translational Cardiology, Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, Via Sommarive 18, 38123, Povo, Trento, Italy.
Ravelli F; Laboratory of Biophysics and Translational Cardiology, Department of Cellular, Computational and Integrative Biology-CIBIO, University of Trento, Via Sommarive 18, 38123, Povo, Trento, Italy.; CISMed-Centre for Medical Sciences, University of Trento, 38122, Trento, Italy.
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Źródło:
Scientific reports [Sci Rep] 2024 May 19; Vol. 14 (1), pp. 11427. Date of Electronic Publication: 2024 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Fibrosis*
Heart Atria*/physiopathology
Heart Atria*/pathology
Atrial Fibrillation*/physiopathology
Atrial Fibrillation*/pathology
Computer Simulation*
Models, Cardiovascular*
Humans ; Algorithms
Czasopismo naukowe
Tytuł:
Development and validation of the Michigan Chronic Disease Simulation Model (MICROSIM).
Autorzy:
Burke JF; Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, United States of America.
Copeland LL; Independent Software Developer, Ann Arbor, MI, United States of America.
Sussman JB; Department of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, United States of America.; Institute for Healthcare Policy and Innovation, U-M, Ann Arbor, MI, United States of America.; Ann Arbor Veteran's Affairs Hospital, Center for Clinical Management and Research, Ann Arbor, MI, United States of America.
Hayward RA; Department of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, United States of America.; Institute for Healthcare Policy and Innovation, U-M, Ann Arbor, MI, United States of America.; Ann Arbor Veteran's Affairs Hospital, Center for Clinical Management and Research, Ann Arbor, MI, United States of America.
Gross AL; Department of Epidemiology, Johns Hopkins Bloomberg School Public Health, Baltimore, MD, United States of America.
Briceño EM; Department of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, United States of America.; Department of Physical Medicine and Rehabilitation, U-M, Ann Arbor, MI, United States of America.
Whitney R; Department of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, United States of America.
Giordani BJ; Department of Psychiatry & Michigan Alzheimer's Disease Center, U-M, Ann Arbor, MI, United States of America.
Elkind MSV; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States of America.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States of America.
Manly JJ; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, United States of America.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, NY, United States of America.
Gottesman RF; Stroke Branch, National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, MD, United States of America.
Gaskin DJ; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
Sidney S; Kaiser Permanente Northern California Division of Research, Oakland, CA, United States of America.
Yaffe K; Departments of Psychiatry, Neurology and Epidemiology, University of California, San Francisco, San Francisco, CA, United States of America.
Sacco RL; Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, United States of America.
Heckbert SR; Department of Epidemiology, University of Washington, Seattle, WA, United States of America.
Hughes TM; Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States of America.
Galecki AT; Department of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, United States of America.; Department of Biostatistics, U-M, Ann Arbor, MI, United States of America.
Levine DA; Department of Internal Medicine and Cognitive Health Services Research Program, University of Michigan (U-M), Ann Arbor, MI, United States of America.; Institute for Healthcare Policy and Innovation, U-M, Ann Arbor, MI, United States of America.
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Źródło:
PloS one [PLoS One] 2024 May 16; Vol. 19 (5), pp. e0300005. Date of Electronic Publication: 2024 May 16 (Print Publication: 2024).
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Computer Simulation*
Humans ; Michigan/epidemiology ; Chronic Disease ; Male ; Dementia/epidemiology ; Aged ; Female ; Risk Factors ; Monte Carlo Method ; Blood Pressure ; Middle Aged ; Cardiovascular Diseases/epidemiology ; Adult ; Alzheimer Disease ; Aged, 80 and over
Czasopismo naukowe
Tytuł:
Numerical simulation of temperature field of a new type of freezing device under seepage effect.
Autorzy:
Yang N; School of Architecture and Construction, Jiangsu Vocational Institute of Architectural Technology, Xuzhou, China.; JiangSu Collaborative Innovation Center for Building Energy Saving and Construct Technology, Xuzhou, Jiangsu, China.
Wang X; Qingdao Geologic and Mineral Geolechnical Engineering Co.,Ltd., Qingdao Shandong, China.
Ren J; School of Civil Engineering and Architecture, Hainan University, Haikou, China.
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Źródło:
PloS one [PLoS One] 2024 May 16; Vol. 19 (5), pp. e0298003. Date of Electronic Publication: 2024 May 16 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Freezing*
Computer Simulation*
Temperature ; Models, Theoretical ; Groundwater
Czasopismo naukowe
Tytuł:
An integrated in-silico approach for drug target identification in human pathogen Shigella dysenteriae.
Autorzy:
Qureshi H; Department of Biological Sciences, National University of Medical Sciences, Islamabad, Pakistan.
Basheer A; Department of Biological Sciences, National University of Medical Sciences, Islamabad, Pakistan.
Sajjad W; Department of Biological Sciences, National University of Medical Sciences, Islamabad, Pakistan.
Faheem M; Department of Biological Sciences, National University of Medical Sciences, Islamabad, Pakistan.; Department of Biomedical Sciences, University of North Dakota, School of Medicine and Health Sciences, Grand Forks, ND, United States of America.
Babar Jamal S; Department of Biological Sciences, National University of Medical Sciences, Islamabad, Pakistan.
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Źródło:
PloS one [PLoS One] 2024 May 16; Vol. 19 (5), pp. e0303048. Date of Electronic Publication: 2024 May 16 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Shigella dysenteriae*/drug effects
Shigella dysenteriae*/genetics
Shigella dysenteriae*/pathogenicity
Anti-Bacterial Agents*/pharmacology
Molecular Docking Simulation*
Computer Simulation*
Dysentery, Bacillary*/microbiology
Dysentery, Bacillary*/drug therapy
Humans ; Genome, Bacterial ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Computational Biology/methods
Czasopismo naukowe
Tytuł:
In silico model development and optimization of in vitro lung cell population growth.
Autorzy:
Mostofinejad A; Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada.
Romero DA; Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada.
Brinson D; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.
Marin-Araujo AE; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.; Latner Research Laboratories, Division of Thoracic Surgery, University Health Network, Toronto, Ontario, Canada.
Bazylak A; Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada.
Waddell TK; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.; Latner Research Laboratories, Division of Thoracic Surgery, University Health Network, Toronto, Ontario, Canada.
Haykal S; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.; Division of Plastic Surgery, University Health Network, Toronto, Ontario, Canada.
Karoubi G; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.; Latner Research Laboratories, Division of Thoracic Surgery, University Health Network, Toronto, Ontario, Canada.
Amon CH; Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, Ontario, Canada.; Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.
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Źródło:
PloS one [PLoS One] 2024 May 15; Vol. 19 (5), pp. e0300902. Date of Electronic Publication: 2024 May 15 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Computer Simulation*
Models, Biological*
Cell Proliferation*
Lung*/cytology
Lung*/metabolism
Humans ; Cell Line ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; Tissue Engineering/methods ; Glucose/metabolism ; Oxygen/metabolism
Czasopismo naukowe
Tytuł:
Simulation study to evaluate when Plasmode simulation is superior to parametric simulation in estimating the mean squared error of the least squares estimator in linear regression.
Autorzy:
Stolte M; Department of Statistics, TU Dortmund University, Dortmund, North Rhine-Westphalia, Germany.
Schreck N; Division of Biostatistics, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany.
Slynko A; Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Ontario, Canada.
Saadati M; Division of Biostatistics, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany.
Benner A; Division of Biostatistics, German Cancer Research Center, Heidelberg, Baden-Wuerttemberg, Germany.
Rahnenführer J; Department of Statistics, TU Dortmund University, Dortmund, North Rhine-Westphalia, Germany.
Bommert A; Department of Statistics, TU Dortmund University, Dortmund, North Rhine-Westphalia, Germany.
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Źródło:
PloS one [PLoS One] 2024 May 15; Vol. 19 (5), pp. e0299989. Date of Electronic Publication: 2024 May 15 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Computer Simulation*
Least-Squares Analysis ; Linear Models ; Humans
Czasopismo naukowe
Tytuł:
Vesicle and reaction-diffusion hybrid modeling with STEPS.
Autorzy:
Hepburn I; Computational Neuroscience Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Okinawa, Japan.
Lallouette J; Computational Neuroscience Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Okinawa, Japan.
Chen W; Computational Neuroscience Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Okinawa, Japan.
Gallimore AR; Computational Neuroscience Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Okinawa, Japan.
Nagasawa-Soeda SY; Computational Neuroscience Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Okinawa, Japan.
De Schutter E; Computational Neuroscience Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Okinawa, Japan. .
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Źródło:
Communications biology [Commun Biol] 2024 May 15; Vol. 7 (1), pp. 573. Date of Electronic Publication: 2024 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Computer Simulation*
Diffusion ; Models, Biological ; Software ; Synaptic Vesicles/metabolism ; Exocytosis/physiology ; Animals ; Humans ; Endocytosis/physiology ; Neurons/physiology ; Neurons/metabolism ; Stochastic Processes
Czasopismo naukowe
Tytuł:
An evaluation of computational methods for aggregate data meta-analyses of diagnostic test accuracy studies.
Autorzy:
Zhao Y; Department of Statistics and Actuarial Science, University of Waterloo, 200 University Ave W, Waterloo, N2L 3G1, Ontario, Canada.
Khan B; Department of Statistics and Actuarial Science, University of Waterloo, 200 University Ave W, Waterloo, N2L 3G1, Ontario, Canada.
Negeri ZF; Department of Statistics and Actuarial Science, University of Waterloo, 200 University Ave W, Waterloo, N2L 3G1, Ontario, Canada. .
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Źródło:
BMC medical research methodology [BMC Med Res Methodol] 2024 May 10; Vol. 24 (1), pp. 111. Date of Electronic Publication: 2024 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diagnostic Tests, Routine*/methods
Diagnostic Tests, Routine*/standards
Diagnostic Tests, Routine*/statistics & numerical data
Meta-Analysis as Topic*
Computer Simulation*
Humans ; Linear Models ; Algorithms ; Likelihood Functions ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł:
Conditional independence as a statistical assessment of evidence integration processes.
Autorzy:
Salinas E; Department of Neurobiology & Anatomy, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America.
Stanford TR; Department of Neurobiology & Anatomy, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America.
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Źródło:
PloS one [PLoS One] 2024 May 09; Vol. 19 (5), pp. e0297792. Date of Electronic Publication: 2024 May 09 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Computer Simulation*
Humans ; Probability ; Models, Statistical ; Aging/physiology
Czasopismo naukowe
Tytuł:
Upstrapping to determine futility: predicting future outcomes nonparametrically from past data.
Autorzy:
Wild JL; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. .
Ginde AA; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Lindsell CJ; Department of Biostatistics and Bioinformatics, School of Medicine, Duke University, Durham, NC, USA.
Kaizer AM; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
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Źródło:
Trials [Trials] 2024 May 09; Vol. 25 (1), pp. 312. Date of Electronic Publication: 2024 May 09.
Typ publikacji:
Journal Article
MeSH Terms:
Medical Futility*
Computer Simulation*
Clinical Trials as Topic*/methods
Research Design*
Humans ; Sample Size ; Data Interpretation, Statistical ; Models, Statistical ; Treatment Outcome
Czasopismo naukowe
Tytuł:
Comprehensive characterization of stemness-related lncRNAs in triple-negative breast cancer identified a novel prognostic signature related to treatment outcomes, immune landscape analysis and therapeutic guidance: a silico analysis with in vivo experiments.
Autorzy:
Zhang M; Xiangya Hospital, Central South University, Changsha, 41000, Hunan, People's Republic of China.
Zhang F; Department of General Surgery, The Fourth People's Hospital of Jinan, Jinan, 250000, Shandong, People's Republic of China.
Wang J; Department of Gastrointestinal Surgery, 970 Hospital of the PLA Joint Logistic Support Force, Yantai, 264000, Shandong, People's Republic of China.
Liang Q; Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Zhou W; Department of Oncology, Xiangya Hospital, Central South University, Changsha, 41000, Hunan, People's Republic of China.
Liu J; Department of Otolaryngology-Head and Neck Surgery, QingPu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai, 201700, People's Republic of China. Liujian_.
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Źródło:
Journal of translational medicine [J Transl Med] 2024 May 04; Vol. 22 (1), pp. 423. Date of Electronic Publication: 2024 May 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Triple Negative Breast Neoplasms*/genetics
Triple Negative Breast Neoplasms*/pathology
Triple Negative Breast Neoplasms*/immunology
Neoplastic Stem Cells*/metabolism
Neoplastic Stem Cells*/pathology
Gene Expression Regulation, Neoplastic*
Computer Simulation*
Humans ; Prognosis ; Female ; Treatment Outcome ; Animals ; Kaplan-Meier Estimate ; Gene Regulatory Networks ; Middle Aged ; Cell Line, Tumor ; ROC Curve ; Gene Expression Profiling ; Proportional Hazards Models ; Immunity/genetics ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism
Czasopismo naukowe
Tytuł:
Re-awakening the brain: Forcing transitions in disorders of consciousness by external in silico perturbation.
Autorzy:
Dagnino PC; Computational Neuroscience Group, Center for Brain and Cognition, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Escrichs A; Computational Neuroscience Group, Center for Brain and Cognition, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
López-González A; Computational Neuroscience Group, Center for Brain and Cognition, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.
Gosseries O; Coma Science Group, GIGA Consciousness, University of Liège, Liège, Belgium.; Centre du Cerveau 2, University Hospital of Liège, Liège, Belgium.
Annen J; Coma Science Group, GIGA Consciousness, University of Liège, Liège, Belgium.; Centre du Cerveau 2, University Hospital of Liège, Liège, Belgium.
Sanz Perl Y; Computational Neuroscience Group, Center for Brain and Cognition, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.; Institut du Cerveau et de la Moelle épinière, ICM, Paris, France.
Kringelbach ML; Centre for Eudaimonia and Human Flourishing, University of Oxford, Oxford, United Kingdom.; Department of Psychiatry, University of Oxford, Oxford, United Kingdom.; Center for Music in the Brain, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Laureys S; Joint International Research Unit on Consciousness, CERVO Brain Research Centre, University of Laval, Québec, Québec, Canada.
Deco G; Computational Neuroscience Group, Center for Brain and Cognition, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, Catalonia, Spain.; Institució Catalana de la Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2024 May 03; Vol. 20 (5), pp. e1011350. Date of Electronic Publication: 2024 May 03 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Magnetic Resonance Imaging*/methods
Brain*/physiopathology
Brain*/diagnostic imaging
Consciousness Disorders*/physiopathology
Consciousness Disorders*/diagnostic imaging
Computer Simulation*
Models, Neurological*
Humans ; Male ; Female ; Computational Biology ; Adult ; Middle Aged ; Consciousness/physiology ; Brain Mapping/methods ; Aged
Czasopismo naukowe
Tytuł:
A versatilely high fidelity electric machines emulator for rapid testing of motor controller.
Autorzy:
Guo Y; School of Mechanical Engineering, Chengdu University, Chengdu, China.
Huang L; School of Mechanical Engineering, Chengdu University, Chengdu, China.
Zhang M; Hezhou University, Hezhou, China.
He M; Hezhou University, Hezhou, China.
Zhong B; School of Mechanical Engineering, Chengdu University, Chengdu, China.
Fan D; School of Mechanical Engineering, Chengdu University, Chengdu, China.
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Źródło:
PloS one [PLoS One] 2024 May 02; Vol. 19 (5), pp. e0299371. Date of Electronic Publication: 2024 May 02 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Computer Simulation*
Models, Theoretical ; Electricity
Czasopismo naukowe
Tytuł:
Development of a physiologically-based pharmacokinetic model to simulate the pharmacokinetics of intramuscular antiretroviral drugs.
Autorzy:
Bettonte S; Division of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital Basel, Basel, Switzerland.; Faculty of Medicine, University of Basel, Basel, Switzerland.
Berton M; Division of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital Basel, Basel, Switzerland.; Faculty of Medicine, University of Basel, Basel, Switzerland.
Battegay M; Division of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital Basel, Basel, Switzerland.; Faculty of Medicine, University of Basel, Basel, Switzerland.
Stader F; Certara UK Limited, Sheffield, UK.
Marzolini C; Division of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital Basel, Basel, Switzerland.; Faculty of Medicine, University of Basel, Basel, Switzerland.; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.; Service and Laboratory of Clinical Pharmacology, Department of Laboratory Medicine and Pathology, University Hospital Lausanne and University of Lausanne, Lausanne, Switzerland.
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Źródło:
CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 May; Vol. 13 (5), pp. 781-794. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Biological*
Rilpivirine*/pharmacokinetics
Rilpivirine*/administration & dosage
Computer Simulation*
Humans ; Injections, Intramuscular ; Paliperidone Palmitate/pharmacokinetics ; Paliperidone Palmitate/administration & dosage ; Delayed-Action Preparations/pharmacokinetics ; Male ; Adult ; Anti-Retroviral Agents/pharmacokinetics ; Anti-Retroviral Agents/administration & dosage ; Drug Liberation ; Middle Aged ; Anti-HIV Agents/pharmacokinetics ; Anti-HIV Agents/administration & dosage ; Female ; Pyridones ; Diketopiperazines
Czasopismo naukowe
Tytuł:
Synergistic epistasis among cancer drivers can rescue early tumors from the accumulation of deleterious passengers.
Autorzy:
Alejandre C; Centro de Astrobiología (CAB) CSIC-INTA, Torrejón de Ardoz, Madrid, Spain.; Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, Spain.
Calle-Espinosa J; Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, Spain.
Iranzo J; Centro de Astrobiología (CAB) CSIC-INTA, Torrejón de Ardoz, Madrid, Spain.; Centro de Biotecnología y Genómica de Plantas, Universidad Politécnica de Madrid (UPM)-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA-CSIC), Madrid, Spain.; Institute for Biocomputation and Physics of Complex Systems (BIFI), University of Zaragoza, Zaragoza, Spain.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2024 Apr 30; Vol. 20 (4), pp. e1012081. Date of Electronic Publication: 2024 Apr 30 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epistasis, Genetic*/genetics
Neoplasms*/genetics
Computer Simulation*
Models, Genetic*
Mutation*
Humans ; Computational Biology/methods ; Gene Regulatory Networks/genetics
Czasopismo naukowe
Tytuł:
A Structural In Silico Analysis of the Immunogenicity of L-Asparaginase from Penicillium cerradense .
Autorzy:
Andrade KCR; Laboratory of Natural Products, Department of Pharmacy, Faculty of Health Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
Homem-de-Mello M; inSiliTox, Department of Pharmacy, Faculty of Health Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
Motta JA; inSiliTox, Department of Pharmacy, Faculty of Health Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
Borges MG; Laboratory of Natural Products, Department of Pharmacy, Faculty of Health Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
de Abreu JAC; Laboratory of Natural Products, Department of Pharmacy, Faculty of Health Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
de Souza PM; Laboratory of Natural Products, Department of Pharmacy, Faculty of Health Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
Pessoa A; Department of Biochemical and Pharmaceutical Technology, School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.
Pappas GJ Jr; Department Cell Biology, Institute Biological Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
de Oliveira Magalhães P; Laboratory of Natural Products, Department of Pharmacy, Faculty of Health Sciences, University of Brasilia, Brasilia 70910-900, Brazil.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 27; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 27.
Typ publikacji:
Journal Article
MeSH Terms:
Asparaginase*/chemistry
Asparaginase*/immunology
Asparaginase*/metabolism
Penicillium*/immunology
Penicillium*/enzymology
Computer Simulation*
Amino Acid Sequence ; Fungal Proteins/chemistry ; Fungal Proteins/immunology ; Fungal Proteins/metabolism ; Epitopes, B-Lymphocyte/immunology ; Epitopes, B-Lymphocyte/chemistry ; Epitopes, T-Lymphocyte/immunology ; Epitopes, T-Lymphocyte/chemistry ; Humans ; Aspergillus/immunology ; Aspergillus/enzymology ; Escherichia coli/genetics ; Dickeya chrysanthemi/enzymology ; Dickeya chrysanthemi/immunology ; Models, Molecular
Czasopismo naukowe
Tytuł:
Numerical simulation of rock blasting under different in-situ stresses and joint conditions.
Autorzy:
Rong H; College of Mining, Liaoning Technical University, Fuxin, China.
Li N; College of Mining, Liaoning Technical University, Fuxin, China.
Cao C; College of Mining, Liaoning Technical University, Fuxin, China.
Wang Y; College of Mining, Liaoning Technical University, Fuxin, China.
Li J; College of Mining, Liaoning Technical University, Fuxin, China.
Li M; College of Mining, Liaoning Technical University, Fuxin, China.
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Źródło:
PloS one [PLoS One] 2024 Apr 22; Vol. 19 (4), pp. e0299258. Date of Electronic Publication: 2024 Apr 22 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Stress, Mechanical*
Computer Simulation*
Models, Theoretical ; Explosions
Czasopismo naukowe
Tytuł:
Computational Modeling of Extrasynaptic NMDA Receptors: Insights into Dendritic Signal Amplification Mechanisms.
Autorzy:
Makarov M; Department of Neurobiology, Weizmann Institute of Science, Rehovot 7610001, Israel.; Department of Mental and Physical Health and Preventive Medicine, University of Campania 'Luigi Vanvitelli', 81100 Caserta, Italy.
Papa M; Department of Mental and Physical Health and Preventive Medicine, University of Campania 'Luigi Vanvitelli', 81100 Caserta, Italy.
Korkotian E; Department of Neurobiology, Weizmann Institute of Science, Rehovot 7610001, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 11; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, N-Methyl-D-Aspartate*/metabolism
Dendrites*/metabolism
Synapses*/metabolism
Computer Simulation*
Animals ; Models, Neurological ; Humans ; Signal Transduction
Czasopismo naukowe

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