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Tytuł :
Serotonin functions as a bidirectional guidance molecule regulating growth cone motility.
Autorzy :
Vicenzi S; School of Medicine, University of Tasmania, Hobart, Australia.
Foa L; School of Psychological Sciences, University of Tasmania, Hobart, Australia.
Gasperini RJ; School of Medicine, University of Tasmania, Hobart, Australia. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Mar; Vol. 78 (5), pp. 2247-2262. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Movement/*drug effects
Growth Cones/*drug effects
Sensory Receptor Cells/*drug effects
Serotonin/*pharmacology
Animals ; Axon Guidance/drug effects ; Axons/drug effects ; Axons/metabolism ; Calcium/metabolism ; Cells, Cultured ; Female ; Growth Cones/physiology ; Humans ; Rats, Sprague-Dawley ; Receptor, Serotonin, 5-HT1B ; Receptors, Serotonin, 5-HT2 ; Sensory Receptor Cells/cytology ; Sensory Receptor Cells/metabolism
Czasopismo naukowe
Tytuł :
Axonal Organelles as Molecular Platforms for Axon Growth and Regeneration after Injury.
Autorzy :
Petrova V; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK.
Nieuwenhuis B; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK.; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.
Fawcett JW; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK.; Centre for Reconstructive Neuroscience, Institute of Experimental Medicine CAS, 142 20 Prague, Czech Republic.
Eva R; John van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, Cambridge CB2 0PY, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 11; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Nerve Regeneration*
Spinal Cord Injuries*/metabolism
Spinal Cord Injuries*/pathology
Spinal Cord Injuries*/therapy
Growth Cones/*metabolism
Organelles/*metabolism
Animals ; Growth Cones/pathology ; Humans ; Organelles/pathology
Czasopismo naukowe
Tytuł :
Fmn2 Regulates Growth Cone Motility by Mediating a Molecular Clutch to Generate Traction Forces.
Autorzy :
Ghate K; Indian Institute of Science Education and Research (IISER) Pune, Dr. Homi Bhabha Road, Pune 411008, India.
Mutalik SP; Indian Institute of Science Education and Research (IISER) Pune, Dr. Homi Bhabha Road, Pune 411008, India.
Sthanam LK; Department of Biosciences and Bioengineering, Indian Institute of Technology (IIT) Bombay, Mumbai 400076, India.
Sen S; Department of Biosciences and Bioengineering, Indian Institute of Technology (IIT) Bombay, Mumbai 400076, India.
Ghose A; Indian Institute of Science Education and Research (IISER) Pune, Dr. Homi Bhabha Road, Pune 411008, India. Electronic address: .
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Źródło :
Neuroscience [Neuroscience] 2020 Nov 10; Vol. 448, pp. 160-171. Date of Electronic Publication: 2020 Sep 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Growth Cones*
Traction*
Actins ; Cell Movement ; Neurons
Czasopismo naukowe
Tytuł :
Coronin 2B regulates dendrite outgrowth by modulating actin dynamics.
Autorzy :
Chen Y; The Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science - Shenzhen Fundamental Research Institutions, Shenzhen, China.; University of Chinese Academy of Sciences, Beijing, China.; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
Xu J; The Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science - Shenzhen Fundamental Research Institutions, Shenzhen, China.; University of Chinese Academy of Sciences, Beijing, China.
Zhang Y; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
Ma S; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
Yi W; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
Liu S; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
Yu X; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
Wang J; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
Chen Y; The Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science - Shenzhen Fundamental Research Institutions, Shenzhen, China.; University of Chinese Academy of Sciences, Beijing, China.; Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen-Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, China.
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Źródło :
FEBS letters [FEBS Lett] 2020 Sep; Vol. 594 (18), pp. 2975-2987. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Actins/*metabolism
Growth Cones/*metabolism
Microfilament Proteins/*metabolism
Actins/chemistry ; Actins/genetics ; Animals ; Cytoskeleton/chemistry ; Cytoskeleton/genetics ; Cytoskeleton/metabolism ; Growth Cones/chemistry ; HEK293 Cells ; Humans ; Mice ; Microfilament Proteins/chemistry ; Microfilament Proteins/genetics ; Protein Domains
Czasopismo naukowe
Tytuł :
Breaking symmetry - cell polarity signaling pathways in growth cone guidance and synapse formation.
Autorzy :
Zou Y; Neurobiology Section, Biological Sciences Division, University of California, San Diego, CA 92093, United States. Electronic address: .
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Źródło :
Current opinion in neurobiology [Curr Opin Neurobiol] 2020 Aug; Vol. 63, pp. 77-86. Date of Electronic Publication: 2020 Apr 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Cell Polarity*
Growth Cones*
Axons ; Signal Transduction ; Synapses
Czasopismo naukowe
Tytuł :
Local Translation in Growth Cones and Presynapses, Two Axonal Compartments for Local Neuronal Functions.
Autorzy :
Sasaki Y; Functional Structure Biology Laboratory, Department of Medical Life Science, Yokohama City University Graduate School of Medical Life Science, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.
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Źródło :
Biomolecules [Biomolecules] 2020 Apr 25; Vol. 10 (5). Date of Electronic Publication: 2020 Apr 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Protein Biosynthesis*
Growth Cones/*metabolism
Presynaptic Terminals/*metabolism
Animals ; Growth Cones/physiology ; Humans ; Presynaptic Terminals/physiology ; Ribonucleoproteins/genetics ; Ribonucleoproteins/metabolism
Czasopismo naukowe
Tytuł :
Semaphorin-3A Promotes Degradation of Fragile X Mental Retardation Protein in Growth Cones via the Ubiquitin-Proteasome Pathway.
Autorzy :
Takabatake M; Functional Structure Biology Laboratory, Department of Medical Life Science, Yokohama City University Graduate School of Medical Life Science, Yokohama, Japan.
Goshima Y; Department of Molecular Pharmacology and Neurobiology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Sasaki Y; Functional Structure Biology Laboratory, Department of Medical Life Science, Yokohama City University Graduate School of Medical Life Science, Yokohama, Japan.
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Źródło :
Frontiers in neural circuits [Front Neural Circuits] 2020 Feb 28; Vol. 14, pp. 5. Date of Electronic Publication: 2020 Feb 28 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fragile X Mental Retardation Protein/*metabolism
Growth Cones/*metabolism
Proteasome Endopeptidase Complex/*metabolism
Semaphorin-3A/*metabolism
Signal Transduction/*physiology
Ubiquitin/*metabolism
Animals ; Cells, Cultured ; Fragile X Mental Retardation Protein/analysis ; Growth Cones/chemistry ; Hippocampus/chemistry ; Hippocampus/metabolism ; Mice ; Proteasome Endopeptidase Complex/analysis ; Semaphorin-3A/analysis ; Ubiquitin/analysis
Czasopismo naukowe
Tytuł :
Microtubules, actin and cytolinkers: how to connect cytoskeletons in the neuronal growth cone.
Autorzy :
Pinto-Costa R; Nerve Regeneration Group, i3S-Instituto de Investigação e Inovação em Saúde and IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal.
Sousa MM; Nerve Regeneration Group, i3S-Instituto de Investigação e Inovação em Saúde and IBMC-Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135, Porto, Portugal. Electronic address: .
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Źródło :
Neuroscience letters [Neurosci Lett] 2021 Mar 16; Vol. 747, pp. 135693. Date of Electronic Publication: 2021 Jan 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Actins/*metabolism
Cytoskeleton/*metabolism
Growth Cones/*metabolism
Microtubules/*metabolism
Actin Cytoskeleton/metabolism ; Animals ; Axons/physiology ; Nerve Regeneration ; Neuronal Outgrowth/physiology ; Neurons/metabolism
Czasopismo naukowe
Tytuł :
Stoichiometry counts.
Autorzy :
Chao MV; Skirball Institute of Biomolecular Medicine, New York University Langone School of Medicine, New York, NY 10012 .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Oct 22; Vol. 116 (43), pp. 21343-21345. Date of Electronic Publication: 2019 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Comment
MeSH Terms :
Apoptosis*
Growth Cones*
Diffusion ; Ligands ; Nerve Growth Factors
Czasopismo naukowe

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