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Tytuł :
Copper Dependent Modulation of α-Synuclein Phosphorylation in Differentiated SHSY5Y Neuroblastoma Cells.
Autorzy :
Greco M; Department of Mathematics and Physics 'E. De Giorgi', University of Salento, 73100 Lecce, Italy.
Spinelli CC; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
De Riccardis L; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Buccolieri A; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Di Giulio S; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Musarò D; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Pagano C; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
Manno D; Department of Mathematics and Physics 'E. De Giorgi', University of Salento, 73100 Lecce, Italy.
Maffia M; Department of Biological and Environmental Science and Technology, University of Salento, 73100 Lecce, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 18; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article
MeSH Terms :
Copper/*metabolism
Neuroblastoma/*metabolism
Neuroblastoma/*pathology
alpha-Synuclein/*metabolism
Cell Differentiation/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Copper/pharmacology ; Copper Transport Proteins/genetics ; Copper Transport Proteins/metabolism ; Copper-Transporting ATPases/genetics ; Copper-Transporting ATPases/metabolism ; Humans ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Phosphorylation/drug effects ; Protein-Serine-Threonine Kinases/genetics ; Protein-Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
[Inhibition of Copper Transporter-1 by Ammonium Tetrathiocarbolybdate in the Treatment of Pancreatic Cancer].
Autorzy :
Zhao YN; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Chen LH; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Yang XL; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Dong JY; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Wu WB; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Chen D; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Geng RM; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
Ke NW; Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Liu J; Department of Biochemistry & Molecular Biology, West China School of Basic Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
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Źródło :
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition [Sichuan Da Xue Xue Bao Yi Xue Ban] 2020 Sep; Vol. 51 (5), pp. 643-649.
Typ publikacji :
Journal Article
MeSH Terms :
Ammonium Compounds*
Chelating Agents*/pharmacology
Copper Transporter 1*/metabolism
Copper Transporter 1*/pharmacology
Pancreatic Neoplasms*/drug therapy
Animals ; Cell Line, Tumor ; Cell Proliferation ; Copper ; Humans ; Mice ; Mice, Nude ; Vascular Endothelial Growth Factor A/metabolism
SCR Disease Name :
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł :
Chronic tribasic copper chloride exposure induces rat liver damage by disrupting the mitophagy and apoptosis pathways.
Autorzy :
Yu W; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China.
Liao J; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China.
Yang F; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China; Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, PR China.
Zhang H; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China.
Chang X; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China.
Yang Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China.
Bilal RM; Faculty of Veterinary and Animal Sciences, The Islamia University of Bahawalpur, 63100 Pakistan.
Wei G; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China.
Liang W; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China.
Guo J; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China.
Tang Z; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, PR China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Apr 01; Vol. 212, pp. 111968. Date of Electronic Publication: 2021 Feb 04.
Typ publikacji :
Journal Article
MeSH Terms :
Chlorides/*toxicity
Copper/*toxicity
Animals ; Antioxidants/metabolism ; Apoptosis/drug effects ; Copper Sulfate/analysis ; Diet ; Liver/metabolism ; Male ; Mitophagy/drug effects ; Oxidative Stress/drug effects ; Rats ; Rats, Sprague-Dawley ; Toxicity Tests, Chronic
Czasopismo naukowe
Tytuł :
A Role for Mycobacterium tuberculosis Sigma Factor C in Copper Nutritional Immunity.
Autorzy :
Grosse-Siestrup BT; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Gupta T; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Helms S; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Tucker SL; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Voskuil MI; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Quinn FD; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
Karls RK; Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 20; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
MeSH Terms :
Copper/*pharmacology
Immunity/*drug effects
Mycobacterium tuberculosis/*metabolism
Sigma Factor/*metabolism
Animals ; Bacterial Proteins/metabolism ; Biological Transport/drug effects ; Copper Sulfate/pharmacology ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Bacterial/drug effects ; Mice, SCID ; Microbial Viability/drug effects ; Mutation/genetics ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/growth & development ; Phenotype ; Transcription, Genetic/drug effects ; Virulence/drug effects ; Virulence/genetics
Czasopismo naukowe
Tytuł :
Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content.
Autorzy :
Hartwig C; Departments of Cell Biology, Emory University, Atlanta, Georgia 30322.
Méndez GM; Neuroscience Department, Universidad Central del Caribe, Bayamon, Puerto Rico 00956.
Bhattacharjee S; Neuroscience Institute, Center for Behavioral Neuroscience, Georgia State University, Atlanta, Georgia 30302.
Vrailas-Mortimer AD; School of Biological Sciences, IL State University, Normal, Illinois 617901.
Zlatic SA; Departments of Cell Biology, Emory University, Atlanta, Georgia 30322.
Freeman AAH; The Center for the Study of Human Health, Emory University, Atlanta, Georgia 30322.
Gokhale A; Departments of Cell Biology, Emory University, Atlanta, Georgia 30322.
Concilli M; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli 80078, Italy.
Werner E; Departments of Cell Biology, Emory University, Atlanta, Georgia 30322.
Sapp Savas C; Departments of Cell Biology, Emory University, Atlanta, Georgia 30322.
Rudin-Rush S; Departments of Cell Biology, Emory University, Atlanta, Georgia 30322.
Palmer L; Departments of Cell Biology, Emory University, Atlanta, Georgia 30322.
Shearing N; Departments of Cell Biology, Emory University, Atlanta, Georgia 30322.
Margewich L; School of Biological Sciences, IL State University, Normal, Illinois 617901.
McArthy J; School of Biological Sciences, IL State University, Normal, Illinois 617901.
Taylor S; School of Biological Sciences, IL State University, Normal, Illinois 617901.
Roberts B; Departments of Biochemistry, Emory University, Atlanta, Georgia 30322.
Lupashin V; Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205.
Polishchuk RS; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli 80078, Italy.
Cox DN; Neuroscience Institute, Center for Behavioral Neuroscience, Georgia State University, Atlanta, Georgia 30302.
Jorquera RA; Neuroscience Department, Universidad Central del Caribe, Bayamon, Puerto Rico 00956 .; Institute of Biomedical Sciences, Faculty of Medicine and Faculty of Life Sciences, Universidad Andres Bello, Santiago 8370186, Chile.
Faundez V; Departments of Cell Biology, Emory University, Atlanta, Georgia 30322 .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Jan 13; Vol. 41 (2), pp. 215-233. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Organelle Biogenesis*
Copper/*physiology
Golgi Apparatus/*physiology
Homeostasis/*physiology
Synapses/*physiology
Adenosine Triphosphatases/metabolism ; Animals ; Animals, Genetically Modified ; Cell Line ; Copper/toxicity ; Copper-Transporting ATPases/genetics ; Drosophila ; Electric Stimulation ; Extracellular Space/metabolism ; Female ; Humans ; Male ; RNA, Small Interfering ; Synapses/ultrastructure
Czasopismo naukowe
Tytuł :
Pharmacoproteomics pinpoints HSP70 interaction for correction of the most frequent Wilson disease-causing mutant of ATP7B.
Autorzy :
Concilli M; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.
Petruzzelli R; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.
Parisi S; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples 80131, Italy.
Catalano F; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.; Institute of Biosciences and Bioresources, Consiglio Nazionale delle Ricerche (CNR), Naples 80131, Italy.
Sirci F; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.
Napolitano F; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.
Renda M; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.
Galietta LJV; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.; Department of Translational Medical Sciences, University of Naples Federico II, Naples 80131, Italy.
Di Bernardo D; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy.; Department of Chemical, Materials and Industrial Production Engineering, University of Naples Federico II, Naples 80125, Italy.
Polishchuk RS; Telethon Institute of Genetics and Medicine, Pozzuoli, Naples 80078, Italy; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 22; Vol. 117 (51), pp. 32453-32463. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Copper-Transporting ATPases/*genetics
Copper-Transporting ATPases/*metabolism
Domperidone/*pharmacology
HSP70 Heat-Shock Proteins/*metabolism
Hepatolenticular Degeneration/*genetics
Benzimidazoles/chemistry ; Benzimidazoles/pharmacology ; Cells, Cultured ; Copper/metabolism ; Domperidone/chemistry ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/metabolism ; HSP70 Heat-Shock Proteins/antagonists & inhibitors ; Hep G2 Cells ; Hepatocytes/metabolism ; Hepatolenticular Degeneration/drug therapy ; Hepatolenticular Degeneration/metabolism ; Hepatolenticular Degeneration/pathology ; Humans ; Mutation, Missense ; Nipecotic Acids/chemistry ; Nipecotic Acids/pharmacology ; Protein Transport/drug effects ; Protein Transport/genetics ; Proteomics/methods
Czasopismo naukowe
Tytuł :
Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function.
Autorzy :
Sudhahar V; Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, Georgia.; Department of Pharmacology and Toxicology, Medical College of Georgia at Augusta University, Augusta, Georgia.; Charlie Norwood Veterans Affairs Medical Center, Augusta, Georgia.
Okur MN; Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.
O'Bryan JP; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Hollings Cancer Center, Medical University of South Carolina, Charleston, South Carolina.; Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina.
Minshall RD; Departments of Anesthesiology and Pharmacology, University of Illinois at Chicago, Chicago, Illinois.
Fulton D; Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, Georgia.; Department of Pharmacology and Toxicology, Medical College of Georgia at Augusta University, Augusta, Georgia.
Ushio-Fukai M; Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, Georgia.; Department of Medicine (Cardiology), Medical College of Georgia at Augusta University, Augusta, Georgia.
Fukai T; Vascular Biology Center, Medical College of Georgia at Augusta University, Augusta, Georgia.; Department of Pharmacology and Toxicology, Medical College of Georgia at Augusta University, Augusta, Georgia.; Charlie Norwood Veterans Affairs Medical Center, Augusta, Georgia.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Nov 01; Vol. 319 (5), pp. C933-C944. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Caveolin 1/*genetics
Copper-Transporting ATPases/*genetics
Endothelial Cells/*metabolism
Superoxide Dismutase/*genetics
Superoxide Dismutase-1/*genetics
Animals ; Aorta/cytology ; Aorta/metabolism ; Caveolin 1/deficiency ; Copper/pharmacology ; Copper Transport Proteins/genetics ; Copper Transport Proteins/metabolism ; Copper-Transporting ATPases/metabolism ; Endothelial Cells/cytology ; Endothelial Cells/drug effects ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Gene Expression Regulation ; Male ; Mesenteric Arteries/cytology ; Mesenteric Arteries/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Oxidative Stress ; Primary Cell Culture ; Proteasome Endopeptidase Complex/metabolism ; Proteolysis ; Signal Transduction ; Superoxide Dismutase/metabolism ; Superoxide Dismutase-1/metabolism ; Ubiquitination/drug effects ; Vasodilation/drug effects
Czasopismo naukowe
Tytuł :
The Response of the Planorbid Snail Isidorella newcombi to Chronic Copper Exposure Over a 28-Day Period: Linking Mortality, Cellular Biomarkers, and Reproductive Responses.
Autorzy :
Ubrihien RP; Centre for Applied Water Science, University of Canberra, Canberra, ACT, 2601, Australia. .
Maher WA; Research School of Earth Science, Australian National University, Canberra, ACT, 2601, Australia.
Taylor AM; Centre for Applied Water Science, University of Canberra, Canberra, ACT, 2601, Australia.
Stevens MM; NSW Department of Primary Industries, Yanco Agricultural Institute, Private Mail Bag, Yanco, NSW, 2703, Australia.; Graham Centre for Agricultural Innovation, NSW Department of Primary Industries and Charles Sturt University, North Wagga Wagga, NSW, Australia.
Ezaz T; Centre for Conservation Ecology and Genetics, University of Canberra, Canberra, ACT, 2601, Australia.
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Źródło :
Archives of environmental contamination and toxicology [Arch Environ Contam Toxicol] 2020 Nov; Vol. 79 (4), pp. 391-405. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
MeSH Terms :
Copper/*toxicity
Snails/*physiology
Water Pollutants, Chemical/*toxicity
Animals ; Biomarkers ; Copper/analysis ; Copper Sulfate ; Fresh Water ; Reproduction ; Toxicity Tests, Chronic ; Water Pollutants, Chemical/analysis
Czasopismo naukowe
Tytuł :
Relative Risk of Cervical Neoplasms Among Copper and Levonorgestrel-Releasing Intrauterine System Users.
Autorzy :
Sel G; Zonguldak Bulent Ecevit University, Zonguldak, Turkey.
Yaşar O
Aynali B
Dinçer F
Novruzova K
Darka İ
Akdemir AY
Harma M
Harma Mİ
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Źródło :
Obstetrics and gynecology [Obstet Gynecol] 2020 Jun; Vol. 135 (6), pp. 1486-1487.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Intrauterine Devices, Copper*/adverse effects
Intrauterine Devices, Medicated*/adverse effects
Uterine Cervical Neoplasms*/epidemiology
Copper ; Female ; Humans ; Levonorgestrel/adverse effects ; Risk
Czasopismo naukowe
Tytuł :
Mechanism of CuSO 4 cytotoxicity in goat erythrocytes after high-level in vitro exposure to isotonic media.
Autorzy :
Tao D; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Wang Y; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Liu J; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Chen R; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Qi M; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China.
Xu S; College of Animal Science, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China; Key Laboratory of Tarim Animal Husbandry Technology Corps, Tarim University, Alar, Xinjiang Uygur Autonomous Region 843300, PR China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Jan 15; Vol. 208, pp. 111730. Date of Electronic Publication: 2020 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
Copper Sulfate/*toxicity
Hazardous Substances/*toxicity
Adenosine Triphosphatases/metabolism ; Animals ; Antioxidants/metabolism ; Copper/analysis ; Erythrocyte Membrane/chemistry ; Erythrocyte Membrane/drug effects ; Erythrocyte Membrane/metabolism ; Erythrocytes/drug effects ; Goats/metabolism ; Hemolysis/drug effects ; Osmotic Fragility/drug effects ; Oxidative Stress/drug effects ; Phospholipids/analysis ; Toxicity Tests
Czasopismo naukowe
Tytuł :
Copper mediates mitochondrial biogenesis in retinal pigment epithelial cells.
Autorzy :
Aloysius Dhivya M; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India; SASTRA deemed to be University, Trichy - Tanjore Road, Thirumalaisamudram, Thanjavur, Tamil Nadu 613401, India.
Aberami S; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India.
Nikhalashree S; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India; SASTRA deemed to be University, Trichy - Tanjore Road, Thirumalaisamudram, Thanjavur, Tamil Nadu 613401, India.
Biswas J; Department of Uveitis, Medical Research Foundation, India.
Liu W; Department of Bioengineering, Cancer Center at Illinois, Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Irudayaraj J; Department of Bioengineering, Cancer Center at Illinois, Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Sulochana KN; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India.
Coral K; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India. Electronic address: .
Bharathi Devi SR; R S Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, College Road, Nungambakkam, Chennai - 6, India. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Oct 01; Vol. 1866 (10), pp. 165843. Date of Electronic Publication: 2020 May 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Organelle Biogenesis*
Copper/*metabolism
Epithelial Cells/*metabolism
Macular Degeneration/*metabolism
Mitochondria/*metabolism
Retinal Pigment Epithelium/*metabolism
Retinal Pigments/*metabolism
Aged ; Aged, 80 and over ; Cell Line ; Choroid/metabolism ; Copper/pharmacology ; Copper Transporter 1/metabolism ; DNA-Binding Proteins/metabolism ; Electron Transport Complex IV/metabolism ; Female ; Gene Expression Regulation/drug effects ; Humans ; Macular Degeneration/pathology ; Male ; Mitochondria/genetics ; Mitochondrial Proteins/metabolism ; Molecular Chaperones/metabolism ; NF-E2-Related Factor 2/metabolism ; RNA, Messenger/metabolism ; RNA-Binding Proteins/metabolism ; Reactive Oxygen Species/metabolism ; Retinal Pigment Epithelium/pathology ; Retinal Pigments/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Activation of HIF-1 signaling ameliorates liver steatosis in zebrafish atp7b deficiency (Wilson's disease) models.
Autorzy :
Mi X; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Li Z; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yan J; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Li Y; School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Zheng J; Department of Pathology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Zhuang Z; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Yang W; Department of Pathology, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Gong L; Department of Infectious Disease, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
Shi J; Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China; Department of Infectious Disease, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2020 Oct 01; Vol. 1866 (10), pp. 165842. Date of Electronic Publication: 2020 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Copper-Transporting ATPases/*genetics
Fatty Liver/*metabolism
Hepatolenticular Degeneration/*genetics
Hepatolenticular Degeneration/*metabolism
Hypoxia-Inducible Factor 1/*metabolism
Liver/*metabolism
Signal Transduction/*physiology
Zebrafish Proteins/*genetics
Animals ; CRISPR-Cas Systems ; Copper/metabolism ; Copper/toxicity ; Disease Models, Animal ; Fatty Liver/genetics ; Fatty Liver/pathology ; Female ; Gene Knockout Techniques ; Hep G2 Cells ; Hepatocytes/metabolism ; Humans ; Liver/pathology ; Male ; Mutation ; Zebrafish
Czasopismo naukowe
Tytuł :
Variations in ATP7B in cats with primary copper-associated hepatopathy.
Autorzy :
Asada H; Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Chambers JK; Department of Veterinary Pathology, Graduate School of Agricultural and Life Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Kojima M; Veterinary Medical Center, Graduate School of Agricultural and Life Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Goto-Koshino Y; Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Nakagawa T; Veterinary Medical Center, Graduate School of Agricultural and Life Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Yokoyama N; Veterinary Medical Center, Graduate School of Agricultural and Life Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Tsuboi M; Department of Veterinary Pathology, Graduate School of Agricultural and Life Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Uchida K; Department of Veterinary Pathology, Graduate School of Agricultural and Life Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Tsujimoto H; Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Ohno K; Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
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Źródło :
Journal of feline medicine and surgery [J Feline Med Surg] 2020 Aug; Vol. 22 (8), pp. 753-759. Date of Electronic Publication: 2019 Nov 05.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Cat Diseases/*genetics
Copper-Transporting ATPases/*genetics
Hepatolenticular Degeneration/*veterinary
Liver/*enzymology
Animals ; Cats ; Copper/blood ; Copper-Transporting ATPases/metabolism ; Female ; Hepatolenticular Degeneration/genetics ; Liver/pathology ; Male
Czasopismo naukowe
Tytuł :
Effects of soybean oil and dietary copper levels on nutrient digestion, ruminal fermentation, enzyme activity, microflora and microbial protein synthesis in dairy bulls.
Autorzy :
Shang X; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Wang C; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Zhang G; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Liu Q; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Guo G; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Huo W; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Zhang J; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
Pei C; College of Animal Science and Veterinary Medicine, Shanxi Agricultural University , Taigu, Shanxi, P R China.
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Źródło :
Archives of animal nutrition [Arch Anim Nutr] 2020 Aug; Vol. 74 (4), pp. 257-270. Date of Electronic Publication: 2019 Nov 13.
Typ publikacji :
Journal Article
MeSH Terms :
Digestion*
Bacteria/*metabolism
Cattle/*physiology
Copper Sulfate/*metabolism
Rumen/*enzymology
Rumen/*microbiology
Soybean Oil/*metabolism
Animal Feed/analysis ; Animals ; Bacterial Proteins/biosynthesis ; Copper/administration & dosage ; Copper/metabolism ; Copper Sulfate/administration & dosage ; Dairying ; Diet/veterinary ; Dietary Supplements/analysis ; Fermentation ; Gastrointestinal Microbiome/physiology ; Male ; Nutrients/physiology ; Soybean Oil/administration & dosage
Czasopismo naukowe
Tytuł :
Role of metal speciation in the exposure medium on the toxicity, bioavailability and bio-reactivity of copper, silver, cadmium and zinc in the rainbow trout gut cell line (RTgutGC).
Autorzy :
Ibrahim M; Department of Integrative Biology, Oklahoma State University, Stillwater, OK, USA.
Oldham D; Department of Integrative Biology, Oklahoma State University, Stillwater, OK, USA.
Minghetti M; Department of Integrative Biology, Oklahoma State University, Stillwater, OK, USA. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP [Comp Biochem Physiol C Toxicol Pharmacol] 2020 Oct; Vol. 236, pp. 108816. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Cadmium/*toxicity
Copper/*toxicity
Oncorhynchus mykiss/*physiology
Silver/*toxicity
Zinc/*toxicity
Animals ; Biological Availability ; Cadmium/pharmacokinetics ; Cation Transport Proteins/genetics ; Cation Transport Proteins/metabolism ; Cells, Cultured ; Copper/pharmacokinetics ; Copper-Transporting ATPases/genetics ; Copper-Transporting ATPases/metabolism ; Gastrointestinal Microbiome/drug effects ; Metallothionein/genetics ; Metallothionein/metabolism ; Silver/metabolism ; Zinc/pharmacokinetics
Czasopismo naukowe
Tytuł :
Integration of transcriptomic and metabolomic data reveals metabolic pathway alteration in mouse spermatogonia with the effect of copper exposure.
Autorzy :
Lin S; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China; Department of Histology and Embryology, Anhui Medicial University, Hefei, 230032, China.
Qiao N; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Chen H; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Tang Z; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Han Q; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China.
Mehmood K; University College of Veterinary & Animal Sciences, Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Fazlani SA; Lasbela University of Agriculture Water & Marine Sciences, Uthal Balochistan Pakistan, Pakistan.
Hameed S; University College of Veterinary & Animal Sciences, Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Li Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. Electronic address: .
Zhang H; College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2020 Oct; Vol. 256, pp. 126974. Date of Electronic Publication: 2020 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Copper/*toxicity
Environmental Pollutants/*toxicity
Spermatogonia/*drug effects
Animals ; Copper Sulfate/pharmacology ; Down-Regulation/drug effects ; Male ; Metabolic Networks and Pathways ; Metabolomics ; Mice ; Transcriptome/drug effects ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Antagonistic bioaccumulation of waterborne Cu(II) and Cd(II) in common carp (Cyprinus carpio) and effects on ion-homeostasis and defensive mechanisms.
Autorzy :
Castaldo G; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium. Electronic address: .
Flipkens G; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Pillet M; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Town RM; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Bervoets L; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
Blust R; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
De Boeck G; Systemic Physiological and Ecotoxicological Research (SPHERE), Department of Biology, University of Antwerp, Groenenborgerlaan 171, 2020 Antwerp, Belgium.
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Źródło :
Aquatic toxicology (Amsterdam, Netherlands) [Aquat Toxicol] 2020 Sep; Vol. 226, pp. 105561. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article
MeSH Terms :
Bioaccumulation/*drug effects
Cadmium/*toxicity
Carps/*metabolism
Copper/*toxicity
Homeostasis/*drug effects
Water Pollutants, Chemical/*toxicity
Animals ; Cadmium/metabolism ; Carps/genetics ; Copper/metabolism ; Copper Transporter 1/genetics ; Copper Transporter 1/metabolism ; Electrolytes/metabolism ; Gills/drug effects ; Gills/metabolism ; Ion Transport ; Lethal Dose 50 ; Potassium/metabolism ; Sodium/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism ; Water Pollutants, Chemical/metabolism
Czasopismo naukowe
Tytuł :
Analysis of Wilson disease mutations revealed that interactions between different ATP7B mutants modify their properties.
Autorzy :
Roy S; Department of Physiology, Johns Hopkins Medical Institute, Baltimore, MD, USA. .; S. N. Pradhan Centre for Neurosciences, University of Calcutta, Kolkata, India. .
McCann CJ; Department of Physiology, Johns Hopkins Medical Institute, Baltimore, MD, USA.
Ralle M; Oregon Health and Science University, Portland, OR, USA.
Ray K; ATGC Diagnostics Private Ltd, Kolkata, India.
Ray J; S. N. Pradhan Centre for Neurosciences, University of Calcutta, Kolkata, India.
Lutsenko S; Department of Physiology, Johns Hopkins Medical Institute, Baltimore, MD, USA. .
Jayakanthan S; Department of Physiology, Johns Hopkins Medical Institute, Baltimore, MD, USA.
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Źródło :
Scientific reports [Sci Rep] 2020 Aug 10; Vol. 10 (1), pp. 13487. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Copper-Transporting ATPases/*genetics
Hepatolenticular Degeneration/*genetics
Adenosine Triphosphatases/metabolism ; Alleles ; Cation Transport Proteins/genetics ; Copper/metabolism ; Copper-Transporting ATPases/metabolism ; Endoplasmic Reticulum/metabolism ; Genetic Association Studies ; HEK293 Cells ; Humans ; Mutation ; Protein Transport ; trans-Golgi Network/genetics ; trans-Golgi Network/metabolism
Czasopismo naukowe
Tytuł :
Process simulation of Ohno continuous casting for single crystal copper prepared from scrap copper in waste printed circuit boards.
Autorzy :
Zhang L; School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Song Q; School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Xu X; School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
Xu Z; School of Environmental Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China; Institute of Pollution Control and Ecological Security, Shanghai 200240, China. Electronic address: .
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Źródło :
Waste management (New York, N.Y.) [Waste Manag] 2021 Apr 01; Vol. 124, pp. 94-101. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article
MeSH Terms :
Copper*
Electronic Waste*/analysis
Recycling ; Solutions ; Temperature
Czasopismo naukowe
Tytuł :
Highly selective electrochemical nitrate reduction using copper phosphide self-supported copper foam electrode: Performance, mechanism, and application.
Autorzy :
Yao F; College of Environmental Science and Engineering, Hunan University, Changsha 410082, P.R. China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, P.R. China. Electronic address: .
Jia M; College of Environmental Science and Engineering, Hunan University, Changsha 410082, P.R. China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, P.R. China.
Yang Q; College of Environmental Science and Engineering, Hunan University, Changsha 410082, P.R. China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, P.R. China. Electronic address: .
Chen F; Key Laboratory of the Three Gorges Reservoir Region's Eco-Environment, Ministry of Education, Chongqing University, Chongqing, 400044, China; College of Environment and Ecology, Chongqing University, Chongqing, 400044, China. Electronic address: .
Zhong Y; Key Laboratory of Water Pollution Control Technology, Hunan Research Academy of Environmental Sciences, Changsha, 410004, P.R. China.
Chen S; College of Environmental Science and Engineering, Hunan University, Changsha 410082, P.R. China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, P.R. China.
He L; College of Environmental Science and Engineering, Hunan University, Changsha 410082, P.R. China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, P.R. China.
Pi Z; College of Environmental Science and Engineering, Hunan University, Changsha 410082, P.R. China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, P.R. China.
Hou K; College of Environmental Science and Engineering, Hunan University, Changsha 410082, P.R. China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, P.R. China.
Wang D; College of Environmental Science and Engineering, Hunan University, Changsha 410082, P.R. China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, P.R. China.
Li X; College of Environmental Science and Engineering, Hunan University, Changsha 410082, P.R. China; Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, 410082, P.R. China.
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Źródło :
Water research [Water Res] 2021 Apr 01; Vol. 193, pp. 116881. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Copper*
Nitrates*
Electrodes ; Nitrogen ; Nitrogen Oxides
Czasopismo naukowe

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