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Tytuł :
Nuclear receptor NR2F6 inhibition potentiates responses to PD-L1/PD-1 cancer immune checkpoint blockade.
Autorzy :
Klepsch V; Division of Translational Cell Genetics, Medical University of Innsbruck, 6020, Innsbruck, Austria.
Hermann-Kleiter N; Division of Translational Cell Genetics, Medical University of Innsbruck, 6020, Innsbruck, Austria.
Do-Dinh P; Division of Translational Cell Genetics, Medical University of Innsbruck, 6020, Innsbruck, Austria.
Jakic B; Division of Translational Cell Genetics, Medical University of Innsbruck, 6020, Innsbruck, Austria.
Offermann A; Pathology of the University Hospital Schleswig-Holstein, Campus Luebeck and Research Center Borstel, Leibniz Lung Center, 23538, Leubeck, Germany.
Efremova M; Biocenter, Division of Bioinformatics, Medical University of Innsbruck, 6030, Innsbruck, Austria.
Sopper S; Tumor Immunology, Tyrolean Cancer Institute & Internal Medicine V, 6020, Innsbruck, Austria.
Rieder D; Biocenter, Division of Bioinformatics, Medical University of Innsbruck, 6030, Innsbruck, Austria.
Krogsdam A; Biocenter, Division of Bioinformatics, Medical University of Innsbruck, 6030, Innsbruck, Austria.
Gamerith G; Tumor Immunology, Tyrolean Cancer Institute & Internal Medicine V, 6020, Innsbruck, Austria.
Perner S; Pathology of the University Hospital Schleswig-Holstein, Campus Luebeck and Research Center Borstel, Leibniz Lung Center, 23538, Leubeck, Germany.
Tzankov A; Department of Pathology, University of Basel, University Hospital Basel, 4031, Basel, Switzerland.
Trajanoski Z; Tumor Immunology, Tyrolean Cancer Institute & Internal Medicine V, 6020, Innsbruck, Austria.
Wolf D; Tumor Immunology, Tyrolean Cancer Institute & Internal Medicine V, 6020, Innsbruck, Austria.; Medical Clinic III, Oncology, Hematology & Rheumatology, University Clinic Bonn, 53127, Bonn, Germany.
Baier G; Division of Translational Cell Genetics, Medical University of Innsbruck, 6020, Innsbruck, Austria. .
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Źródło :
Nature communications [Nat Commun] 2018 Apr 18; Vol. 9 (1), pp. 1538. Date of Electronic Publication: 2018 Apr 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
B7-H1 Antigen/*metabolism
COUP Transcription Factors/*metabolism
Neoplasms/*immunology
Programmed Cell Death 1 Receptor/*metabolism
Receptors, Steroid/*metabolism
Animals ; Biopsy ; COUP Transcription Factors/antagonists & inhibitors ; Disease Progression ; Female ; Gene Silencing ; Heterozygote ; Humans ; Immune System ; Male ; Mice ; Mice, Inbred C57BL ; Neoplasm Transplantation ; Neoplasms/pathology ; RNA, Small Interfering/metabolism ; Receptors, Steroid/antagonists & inhibitors ; Repressor Proteins ; Spleen/metabolism ; T-Lymphocytes/cytology ; Up-Regulation
Czasopismo naukowe
Tytuł :
The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance.
Autorzy :
Hermann-Kleiter N; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria. Electronic address: .
Klepsch V; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Wallner S; Laboratory of Tumor Immunology, Tyrolean Cancer Institute & Internal Medicine V, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Siegmund K; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Klepsch S; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Tuzlak S; Division of Developmental Immunology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Villunger A; Division of Developmental Immunology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Kaminski S; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Pfeifhofer-Obermair C; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Gruber T; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Wolf D; Laboratory of Tumor Immunology, Tyrolean Cancer Institute & Internal Medicine V, Medical University of Innsbruck, 6020 Innsbruck, Austria; Medical Clinic III, Oncology, Hematology & Rheumatology, University Clinic Bonn, 53127 Bonn, Germany.
Baier G; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, 6020 Innsbruck, Austria. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2015 Sep 29; Vol. 12 (12), pp. 2072-85. Date of Electronic Publication: 2015 Sep 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunologic Surveillance*
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
COUP Transcription Factors/*genetics
Immunotherapy, Adoptive/*methods
Prostatic Neoplasms/*therapy
Animals ; CD4-Positive T-Lymphocytes/cytology ; CD4-Positive T-Lymphocytes/transplantation ; CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/transplantation ; COUP Transcription Factors/deficiency ; COUP Transcription Factors/immunology ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Humans ; Immunologic Memory ; Interferon-gamma/agonists ; Interferon-gamma/genetics ; Interferon-gamma/immunology ; Interleukin-2/agonists ; Interleukin-2/genetics ; Interleukin-2/immunology ; Lymphocyte Activation ; Male ; Mice ; Mice, Inbred C57BL ; Neoplasm Transplantation ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/immunology ; Prostatic Neoplasms/mortality ; Repressor Proteins ; Signal Transduction ; Survival Analysis ; Tumor Necrosis Factor-alpha/agonists ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology
Czasopismo naukowe
Tytuł :
Choose your destiny: Make a cell fate decision with COUP-TFII.
Autorzy :
Wu SP; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Adrienne Helis Malvin Medical Research Foundation, New Orleans, LA 70130, USA.
Yu CT; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Tsai SY; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: .
Tsai MJ; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: .
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Źródło :
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2016 Mar; Vol. 157, pp. 7-12. Date of Electronic Publication: 2015 Dec 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Blood Vessels/*cytology
COUP Transcription Factors/*metabolism
Kidney/*cytology
Myocardium/*cytology
Stem Cells/*cytology
Stem Cells/*physiology
Animals ; COUP Transcription Factors/genetics ; Cell Differentiation ; Gene Expression Regulation, Developmental ; Heart/embryology ; Heart Atria/cytology ; Heart Atria/embryology ; Humans ; Kidney/embryology
Czasopismo naukowe
Tytuł :
Orphan nuclear receptor NR2F6 acts as an essential gatekeeper of Th17 CD4+ T cell effector functions.
Autorzy :
Hermann-Kleiter N; Department for Pharmacology and Genetics, Translational Cell Genetics, Medical University of Innsbruck, Peter Mayr Str, 1a, A-6020, Innsbruck, Austria. .
Baier G
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Źródło :
Cell communication and signaling : CCS [Cell Commun Signal] 2014 Jun 12; Vol. 12, pp. 38. Date of Electronic Publication: 2014 Jun 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COUP Transcription Factors/*metabolism
Th17 Cells/*metabolism
Animals ; Autoimmunity ; COUP Transcription Factors/chemistry ; COUP Transcription Factors/genetics ; Cytokines/genetics ; Cytokines/metabolism ; Humans ; Inflammation/immunology ; Inflammation/metabolism ; Th17 Cells/immunology ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
COUP-TFs and eye development.
Autorzy :
Tang K; Institute of Life Science, Nanchang University, Nanchang, Jiangxi 330031, China; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: .
Tsai SY; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: .
Tsai MJ; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: .
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Źródło :
Biochimica et biophysica acta [Biochim Biophys Acta] 2015 Feb; Vol. 1849 (2), pp. 201-9. Date of Electronic Publication: 2014 May 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COUP Transcription Factors/*physiology
Eye/*embryology
Organogenesis/*genetics
Animals ; COUP Transcription Factors/genetics ; Drosophila/embryology ; Drosophila/genetics ; Eye/metabolism ; Eye Diseases/genetics ; Humans ; Mice/embryology ; Mice/genetics ; Xenopus/embryology ; Xenopus/genetics ; Zebrafish/embryology ; Zebrafish/genetics
Czasopismo naukowe
Tytuł :
The nuclear receptors COUP-TF: a long-lasting experience in forebrain assembly.
Autorzy :
Alfano C; Institute of Biology Valrose, iBV, UMR INSERM1091/CNRS7277/UNS, 06108, Nice, France.
Magrinelli E
Harb K
Studer M
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2014 Jan; Vol. 71 (1), pp. 43-62. Date of Electronic Publication: 2013 Mar 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COUP Transcription Factors/*metabolism
Prosencephalon/*metabolism
Animals ; COUP Transcription Factors/chemistry ; COUP Transcription Factors/classification ; Cerebral Cortex/metabolism ; Hippocampus/metabolism ; Humans ; Neurogenesis ; Prosencephalon/growth & development
Czasopismo naukowe
Tytuł :
Nuclear orphan receptor NR2F6 as a safeguard against experimental murine colitis.
Autorzy :
Klepsch V; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, Innsbruck, Tirol, Austria.
Gerner RR; Department of Internal Medicine I, Gastroenterology, Endocrinology & Metabolism, Medical University Innsbruck, Innsbruck, Tirol, Austria.
Klepsch S; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, Innsbruck, Tirol, Austria.
Olson WJ; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, Innsbruck, Tirol, Austria.
Tilg H; Department of Internal Medicine I, Gastroenterology, Endocrinology & Metabolism, Medical University Innsbruck, Innsbruck, Tirol, Austria.
Moschen AR; Department of Internal Medicine I, Gastroenterology, Endocrinology & Metabolism, Medical University Innsbruck, Innsbruck, Tirol, Austria.
Baier G; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, Innsbruck, Tirol, Austria.
Hermann-Kleiter N; Translational Cell Genetics, Department for Pharmacology and Genetics, Medical University of Innsbruck, Innsbruck, Tirol, Austria.
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Źródło :
Gut [Gut] 2018 Aug; Vol. 67 (8), pp. 1434-1444. Date of Electronic Publication: 2017 Aug 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COUP Transcription Factors/*metabolism
Colitis/*metabolism
Colitis/*pathology
Animals ; Colitis/etiology ; Dextran Sulfate ; Disease Models, Animal ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Mice ; Mucin-2/metabolism ; Repressor Proteins ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Tytuł :
Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.
Autorzy :
Hermann-Kleiter N; Department for Pharmacology and Genetics, Medical University Innsbruck, Peter Mayr Str. 1a, A-6020 Innsbruck, Austria. />Meisel M
Fresser F
Thuille N
Müller M
Roth L
Katopodis A
Baier G
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Źródło :
Journal of autoimmunity [J Autoimmun] 2012 Dec; Vol. 39 (4), pp. 428-40. Date of Electronic Publication: 2012 Aug 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COUP Transcription Factors/*immunology
Encephalomyelitis, Autoimmune, Experimental/*immunology
Interleukin-17/*immunology
NFATC Transcription Factors/*immunology
Nuclear Receptor Subfamily 1, Group F, Member 3/*immunology
Th17 Cells/*immunology
Animals ; Binding Sites ; Binding, Competitive ; COUP Transcription Factors/deficiency ; COUP Transcription Factors/genetics ; DNA/immunology ; DNA/metabolism ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/genetics ; Encephalomyelitis, Autoimmune, Experimental/pathology ; Gene Expression Regulation/immunology ; Interleukin-17/genetics ; Interleukin-17/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NFATC Transcription Factors/genetics ; NFATC Transcription Factors/metabolism ; Nuclear Receptor Subfamily 1, Group F, Member 3/genetics ; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism ; Protein Binding ; Repressor Proteins ; Response Elements/immunology ; Signal Transduction ; Th17 Cells/metabolism ; Th17 Cells/pathology ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Expression and retinoic acid regulation of the zebrafish nr2f orphan nuclear receptor genes.
Autorzy :
Love CE; Committee on Development, Regeneration and Stem Cell Biology, The University of Chicago, Chicago, IL 60637, USA.
Prince VE
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Źródło :
Developmental dynamics : an official publication of the American Association of Anatomists [Dev Dyn] 2012 Oct; Vol. 241 (10), pp. 1603-15. Date of Electronic Publication: 2012 Aug 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
COUP Transcription Factors/*metabolism
Central Nervous System/*metabolism
Fibroblast Growth Factors/*metabolism
Gene Expression Regulation, Developmental/*physiology
Signal Transduction/*physiology
Tretinoin/*metabolism
Zebrafish/*embryology
Animals ; COUP Transcription Factors/genetics ; DNA Primers/genetics ; Gene Expression Profiling ; In Situ Hybridization
Czasopismo naukowe
Tytuł :
Regulation of renin expression by the orphan nuclear receptors Nr2f2 and Nr2f6.
Autorzy :
Weatherford ET; Department of Pharmacology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
Liu X
Sigmund CD
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2012 Apr 15; Vol. 302 (8), pp. F1025-33. Date of Electronic Publication: 2012 Jan 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*/drug effects
COUP Transcription Factor II/*metabolism
COUP Transcription Factors/*metabolism
Renin/*genetics
Animals ; Base Sequence ; COUP Transcription Factor II/genetics ; COUP Transcription Factors/genetics ; Cell Line ; Enhancer Elements, Genetic ; Gene Knockdown Techniques ; Mice ; Promoter Regions, Genetic ; Repressor Proteins ; Tretinoin/pharmacology
Czasopismo naukowe
Tytuł :
Modulation of COUP-TF expression in a cnidarian by ectopic Wnt signalling and allorecognition.
Autorzy :
Duffy DJ; School of Natural Sciences and Martin Ryan Marine Science Institute, National University of Ireland Galway, Galway, Ireland.
Frank U
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Źródło :
PloS one [PLoS One] 2011 Apr 28; Vol. 6 (4), pp. e19443. Date of Electronic Publication: 2011 Apr 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Developmental*
Signal Transduction*
COUP Transcription Factors/*genetics
Hydrozoa/*cytology
Hydrozoa/*genetics
Wnt Proteins/*metabolism
Amino Acid Sequence ; Animals ; COUP Transcription Factors/chemistry ; Evolution, Molecular ; Humans ; Hydrozoa/growth & development ; Hydrozoa/immunology ; Molecular Sequence Data ; Neurogenesis/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
COUP-TF Genes, Human Diseases, and the Development of the Central Nervous System in Murine Models.
Autorzy :
Yang X; Institute of Life Science, Nanchang University, Nanchang, Jiangxi, China.
Feng S; Institute of Life Science, Nanchang University, Nanchang, Jiangxi, China.
Tang K; Institute of Life Science, Nanchang University, Nanchang, Jiangxi, China. Electronic address: .
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Źródło :
Current topics in developmental biology [Curr Top Dev Biol] 2017; Vol. 125, pp. 275-301. Date of Electronic Publication: 2017 Jan 18.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Central Nervous System*/embryology
Central Nervous System*/physiology
Gene Expression Regulation, Developmental*
COUP Transcription Factors/*genetics
Animals ; Brain Diseases/genetics ; Disease Models, Animal ; Humans ; Mice ; Organogenesis
Czasopismo naukowe
Tytuł :
Regulation of Oligodendrocyte Differentiation and Myelination by Nuclear Receptors: Role in Neurodegenerative Disorders.
Autorzy :
Sandoval-Hernández A; Grupo de Neurociencias y Muerte Celular, Facultad de Medicina e Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia.
Contreras MJ; Grupo de Neurociencias y Muerte Celular, Facultad de Medicina e Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia.
Jaramillo J; Grupo de Neurociencias y Muerte Celular, Facultad de Medicina e Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia.
Arboleda G; Grupo de Neurociencias y Muerte Celular, Facultad de Medicina e Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia. .; Departamento de Patología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, Colombia. .
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2016; Vol. 949, pp. 287-310.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Adrenoleukodystrophy/*genetics
Alzheimer Disease/*genetics
Oligodendroglia/*metabolism
Receptors, Retinoic Acid/*genetics
Stem Cells/*metabolism
Adrenoleukodystrophy/drug therapy ; Adrenoleukodystrophy/metabolism ; Adrenoleukodystrophy/pathology ; Alzheimer Disease/drug therapy ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Animals ; COUP Transcription Factors/agonists ; COUP Transcription Factors/genetics ; COUP Transcription Factors/metabolism ; Cell Differentiation ; Cell Lineage ; Drugs, Investigational/therapeutic use ; Gene Expression Regulation ; Humans ; Liver X Receptors/agonists ; Liver X Receptors/genetics ; Liver X Receptors/metabolism ; Neuroprotective Agents/therapeutic use ; Oligodendroglia/drug effects ; Oligodendroglia/pathology ; Peroxisome Proliferator-Activated Receptors/agonists ; Peroxisome Proliferator-Activated Receptors/genetics ; Peroxisome Proliferator-Activated Receptors/metabolism ; Receptors, Cytoplasmic and Nuclear/agonists ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, Cytoplasmic and Nuclear/metabolism ; Receptors, Retinoic Acid/agonists ; Receptors, Retinoic Acid/metabolism ; Stem Cells/drug effects ; Stem Cells/pathology
Czasopismo naukowe
Tytuł :
The chicken ovalbumin upstream promoter-transcription factors modulate genes and pathways involved in skeletal muscle cell metabolism.
Autorzy :
Myers SA; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia. />Wang SC
Muscat GE
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2006 Aug 25; Vol. 281 (34), pp. 24149-60. Date of Electronic Publication: 2006 Jun 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*/drug effects
COUP Transcription Factors/*genetics
Muscle, Skeletal/*metabolism
ATP Binding Cassette Transporter 1 ; ATP Binding Cassette Transporter, Subfamily G, Member 1 ; ATP-Binding Cassette Transporters/genetics ; Animals ; COUP Transcription Factors/metabolism ; Cells, Cultured ; Chickens ; DNA-Binding Proteins/agonists ; DNA-Binding Proteins/genetics ; Energy Metabolism/genetics ; Hydrocarbons, Fluorinated ; Lipid Metabolism/genetics ; Lipoproteins/genetics ; Liver X Receptors ; Mice ; Orphan Nuclear Receptors ; RNA, Small Interfering/genetics ; Receptors, Cytoplasmic and Nuclear/agonists ; Receptors, Cytoplasmic and Nuclear/genetics ; Signal Transduction/genetics ; Sulfonamides/pharmacology
Czasopismo naukowe
Tytuł :
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse hippocampus.
Autorzy :
Dabrowski M; Laboratory of Transcription Regulation, Department of Cell Biology, The Nencki Institute of Experimental Biology, Pasteura 3, 02-093 Warsaw, Poland. />Aerts S
Kaminska B
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2006 Aug 02; Vol. 7, pp. 367. Date of Electronic Publication: 2006 Aug 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COUP Transcription Factors/*metabolism
Computational Biology/*methods
E2F Transcription Factors/*metabolism
Hippocampus/*metabolism
Amino Acid Motifs/genetics ; Amino Acid Sequence ; Animals ; Binding Sites/genetics ; COUP Transcription Factors/genetics ; Cell Differentiation/genetics ; Down-Regulation/genetics ; E2F Transcription Factors/genetics ; Gene Expression Profiling/methods ; Gene Expression Regulation, Developmental/genetics ; Hippocampus/growth & development ; Humans ; Mice ; Myoblasts/cytology ; Myoblasts/metabolism ; Protein Binding ; Sequence Homology, Amino Acid
Czasopismo naukowe
Tytuł :
A proteomic analysis reveals that Snail regulates the expression of the nuclear orphan receptor Nuclear Receptor Subfamily 2 Group F Member 6 (Nr2f6) and interleukin 17 (IL-17) to inhibit adipocyte differentiation.
Autorzy :
Peláez-García A; From the ‡Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain;
Barderas R; §Departamento de Biochemistry and Molecular Biology Department I, Universidad Complutense de Madrid, Spain;
Batlle R; ¶IMIM-Hospital del Mar. Barcelona, Spain;
Viñas-Castells R; ¶IMIM-Hospital del Mar. Barcelona, Spain;
Bartolomé RA; From the ‡Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain;
Torres S; From the ‡Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain;
Mendes M; From the ‡Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain;
Lopez-Lucendo M; From the ‡Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain;
Mazzolini R; ¶IMIM-Hospital del Mar. Barcelona, Spain;
Bonilla F; ‖Hospital Puerta de Hierro, Majadahonda, Madrid, Spain.
García de Herreros A; ¶IMIM-Hospital del Mar. Barcelona, Spain;
Casal JI; From the ‡Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas (CIB-CSIC), Madrid, Spain; .
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Źródło :
Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2015 Feb; Vol. 14 (2), pp. 303-15. Date of Electronic Publication: 2014 Dec 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Adipocytes/*cytology
Adipocytes/*metabolism
COUP Transcription Factors/*metabolism
Interleukin-17/*metabolism
Proteomics/*methods
Transcription Factors/*metabolism
3T3-L1 Cells ; Adipogenesis ; Animals ; Cell Extracts ; Cell Nucleus/metabolism ; Down-Regulation ; Mesenchymal Stem Cells/metabolism ; Mice ; Models, Biological ; Repressor Proteins ; Reproducibility of Results ; Signal Transduction ; Snail Family Transcription Factors ; Transfection
Czasopismo naukowe
Tytuł :
Cis-regulatory control of the nuclear receptor Coup-TF gene in the sea urchin Paracentrotus lividus embryo.
Autorzy :
Kalampoki LG; Department of Biology, University of Patras, Patras 26504, Greece.
Flytzanis CN; Department of Biology, University of Patras, Patras 26504, Greece.
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Źródło :
PloS one [PLoS One] 2014 Nov 11; Vol. 9 (11), pp. e109274. Date of Electronic Publication: 2014 Nov 11 (Print Publication: 2014).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcription Initiation Site*
COUP Transcription Factors/*genetics
Gene Expression Regulation, Developmental/*genetics
Paracentrotus/*genetics
Regulatory Sequences, Nucleic Acid/*genetics
Animals ; Base Sequence ; Cloning, Molecular ; DNA-Binding Proteins/genetics ; Electrophoretic Mobility Shift Assay ; Embryo, Nonmammalian ; Paracentrotus/embryology ; Receptors, Cytoplasmic and Nuclear/genetics ; Sequence Deletion/genetics ; Strongylocentrotus purpuratus/genetics ; Transcription Initiation, Genetic
Czasopismo naukowe
Tytuł :
Nuclear hormone receptor expression in mouse kidney and renal cell lines.
Autorzy :
Ogawa D; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan ; Department of Diabetic Nephropathy, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Eguchi J; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Wada J; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Terami N; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Hatanaka T; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Tachibana H; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Nakatsuka A; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan ; Department of Diabetic Nephropathy, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Horiguchi CS; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Nishii N; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Makino H; Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
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Źródło :
PloS one [PLoS One] 2014 Jan 22; Vol. 9 (1), pp. e85594. Date of Electronic Publication: 2014 Jan 22 (Print Publication: 2014).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression*
Diabetic Nephropathies/*genetics
Kidney/*metabolism
Receptors, Cytoplasmic and Nuclear/*genetics
Animals ; COUP Transcription Factor II/genetics ; COUP Transcription Factor II/metabolism ; COUP Transcription Factors/genetics ; COUP Transcription Factors/metabolism ; Cell Line ; Cells, Cultured ; Diabetic Nephropathies/metabolism ; Kidney/cytology ; Kidney Tubules/cytology ; Kidney Tubules/metabolism ; Male ; Mesangial Cells/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Microscopy, Fluorescence ; Nuclear Receptor Subfamily 4, Group A, Member 1/genetics ; Nuclear Receptor Subfamily 4, Group A, Member 1/metabolism ; Podocytes/metabolism ; Receptors, Cytoplasmic and Nuclear/classification ; Receptors, Cytoplasmic and Nuclear/metabolism ; Repressor Proteins ; Reverse Transcriptase Polymerase Chain Reaction
Czasopismo naukowe

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