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Tytuł:
The Role of Ferroptosis and Cuproptosis in Curcumin against Hepatocellular Carcinoma.
Autorzy:
Liu Z; Neurosurgery Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, China.
Ma H; Department of Neurology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
Lai Z; Neurosurgery Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 08; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*
Curcumin*
Ferroptosis*
Liver Neoplasms*
Apoptosis*
Humans ; Copper ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Molecular Mechanisms of Antiproliferative and Apoptosis Activity by 1,5-Bis(4-Hydroxy-3-Methoxyphenyl)1,4-Pentadiene-3-one (MS13) on Human Non-Small Cell Lung Cancer Cells.
Autorzy:
Wan Mohd Tajuddin WNB; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.
Abas F; Laboratory of Natural Products, Faculty of Science, Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia.; Department of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, UPM, Serdang 43400, Malaysia.
Othman I; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.; Global Asia in the 21s Century Platform, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.
Naidu R; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.; Global Asia in the 21s Century Platform, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 10; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 10.
Typ publikacji:
Journal Article
MeSH Terms:
Alkadienes/*chemistry
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Carcinoma, Non-Small-Cell Lung/*pathology
Curcumin/*analogs & derivatives
Lung Neoplasms/*pathology
Antineoplastic Agents/chemistry ; Carcinoma, Non-Small-Cell Lung/metabolism ; Cell Cycle ; Cell Proliferation/drug effects ; Curcumin/chemistry ; Curcumin/pharmacology ; Humans ; Lung Neoplasms/metabolism ; Signal Transduction ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
The Curcumin Analogue, MS13 (1,5-Bis(4-hydroxy-3- methoxyphenyl)-1,4-pentadiene-3-one), Inhibits Cell Proliferation and Induces Apoptosis in Primary and Metastatic Human Colon Cancer Cells.
Autorzy:
Ismail NI; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor, Malaysia.; UniKL MESTECH, A1-1 Jalan TKS1, Taman Kajang Sentral, Kajang 43000, Malaysia.
Othman I; UniKL MESTECH, A1-1 Jalan TKS1, Taman Kajang Sentral, Kajang 43000, Malaysia.
Abas F; Laboratory of Natural Products, Faculty of Science, University Putra Malaysia, Serdang 43400, Malaysia.; Department of Food Science, Faculty of Food Science and Technology, University Putra Malaysia, Serdang 43400, Malaysia.
H Lajis N; Laboratory of Natural Products, Faculty of Science, University Putra Malaysia, Serdang 43400, Malaysia.
Naidu R; Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor, Malaysia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Aug 20; Vol. 25 (17). Date of Electronic Publication: 2020 Aug 20.
Typ publikacji:
Journal Article
MeSH Terms:
Colonic Neoplasms*/drug therapy
Colonic Neoplasms*/metabolism
Colonic Neoplasms*/pathology
Curcumin*/analogs & derivatives
Curcumin*/chemical synthesis
Curcumin*/chemistry
Curcumin*/pharmacology
Cytotoxins*/chemical synthesis
Cytotoxins*/chemistry
Cytotoxins*/pharmacology
Apoptosis/*drug effects
Cell Proliferation/*drug effects
Caspase 3/metabolism ; Cell Line, Tumor ; Humans ; Neoplasm Metastasis ; Proto-Oncogene Proteins c-bcl-2/metabolism
Czasopismo naukowe
Tytuł:
Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2.
Autorzy:
Xu Y; College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, China.
Zheng J; College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, China.
Sun P; Laboratory Animal Center, Shanxi Agricultural University, Taigu, 030801, Shanxi, China.
Guo J; Department of Veterinary Pathobiology, Schubot Exotic Bird Health Center, Texas A&M University, College Station, Texas, TX, 77843, USA.
Zheng X; Medical Research Council (MRC) Centre for Inflammation Research, Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, EH16 4TJ, UK.
Sun Y; College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, China.
Fan K; Laboratory Animal Center, Shanxi Agricultural University, Taigu, 030801, Shanxi, China.
Yin W; College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, China.
Li H; College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, China. .
Sun N; College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, China. .
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Źródło:
BMC veterinary research [BMC Vet Res] 2020 Sep 18; Vol. 16 (1), pp. 345. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Benzylisoquinolines/*pharmacology
Circovirus/*drug effects
Curcumin/*pharmacology
Acetophenones/pharmacology ; Acetophenones/toxicity ; Animals ; Antiviral Agents/pharmacology ; Antiviral Agents/toxicity ; Benzylisoquinolines/toxicity ; Cell Line ; Circoviridae Infections/drug therapy ; Curcumin/toxicity ; Mitochondria/drug effects ; Plant Extracts/pharmacology ; Plant Extracts/toxicity ; Swine
Czasopismo naukowe
Tytuł:
Curcumin-coated gold nanoparticles attenuate doxorubicin-induced cardiotoxicity via regulating apoptosis in a mouse model.
Autorzy:
Sharifiaghdam Z; Student Research Committee, Iran University of Medical Sciences, Tehran, Iran.; Department of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Dalouchi F; Department of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Sharifiaghdam M; Department of Medical Nanotechnology, School of Advanced Technologies in Medicine (SATiM), Tehran University of Medical Sciences (TUMS, Tehran, Iran.; Laboratory of General Biochemistry & Physical Pharmacy, Ghent University, Ghent, Belgium.
Shaabani E; Department of Medical Nanotechnology, School of Advanced Technologies in Medicine (SATiM), Tehran University of Medical Sciences (TUMS, Tehran, Iran.; Laboratory of General Biochemistry & Physical Pharmacy, Ghent University, Ghent, Belgium.
Ramezani F; Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Nikbakht F; Department of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Azizi Y; Department of Physiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.; Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.
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Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2022 Jan; Vol. 49 (1), pp. 70-83. Date of Electronic Publication: 2021 Sep 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Metal Nanoparticles*
Apoptosis/*drug effects
Cardiotoxicity/*drug therapy
Cardiotoxins/*toxicity
Curcumin/*therapeutic use
Doxorubicin/*toxicity
Animals ; Cardiotoxicity/etiology ; Cardiotoxins/antagonists & inhibitors ; Doxorubicin/antagonists & inhibitors ; Gold ; Male ; Mice ; Mice, Inbred BALB C ; Microscopy, Electron, Transmission ; Photoelectron Spectroscopy ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Tytuł:
Curcumin-1,2,3-Triazole Conjugation for Targeting the Cancer Apoptosis Machinery.
Autorzy:
Seghetti F; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Di Martino RMC; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Catanzaro E; Department for Life Quality Studies, Alma Mater Studiorum-University of Bologna, Corso d'Augusto 237, 47921 Rimini, Italy.
Bisi A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Gobbi S; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Rampa A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Canonico B; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via Ca' Le Suore, 2, 61029 Urbino, Italy.
Montanari M; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via Ca' Le Suore, 2, 61029 Urbino, Italy.
Krysko DV; Cell Death Investigation and Therapy Laboratory, Department of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium.; Cancer Research Institute Ghent, 9000 Ghent, Belgium.; Department of Pathophysiology, Sechenov First Moscow State Medical University (Sechenov University), 119146 Moscow, Russia.
Papa S; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via Ca' Le Suore, 2, 61029 Urbino, Italy.
Fimognari C; Department for Life Quality Studies, Alma Mater Studiorum-University of Bologna, Corso d'Augusto 237, 47921 Rimini, Italy.
Belluti F; Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 Jul 05; Vol. 25 (13). Date of Electronic Publication: 2020 Jul 05.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Antineoplastic Agents/*pharmacology
Curcumin/*pharmacology
Leukemia, T-Cell/*pathology
Membrane Potential, Mitochondrial/*drug effects
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*pathology
Triazoles/*chemistry
Antineoplastic Agents/chemistry ; Cell Proliferation ; Curcumin/chemistry ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Leukemia, T-Cell/drug therapy ; Molecular Structure ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Structure-Activity Relationship ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł:
Radiation induced apoptosis and pulmonary fibrosis: curcumin an effective intervention?
Autorzy:
Johnson S; Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India.
Shaikh SB; Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India.
Muneesa F; Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India.
Rashmi B; Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India.
Bhandary YP; Yenepoya Research Centre, Yenepoya (Deemed to be University), Mangalore, India.
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2020 Jun; Vol. 96 (6), pp. 709-717. Date of Electronic Publication: 2020 Mar 20.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Apoptosis/*drug effects
Apoptosis/*radiation effects
Curcumin/*pharmacology
Pulmonary Fibrosis/*drug therapy
Radiation Injuries/*drug therapy
Radiation-Protective Agents/*pharmacology
Animals ; Curcumin/therapeutic use ; Humans ; Pulmonary Fibrosis/etiology ; Radiation Injuries/etiology ; Radiation-Protective Agents/therapeutic use
Czasopismo naukowe
Tytuł:
Curcumin Nicotinate Selectively Induces Cancer Cell Apoptosis and Cycle Arrest through a P53-Mediated Mechanism.
Autorzy:
He YC; Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, State Key Laboratory of Chinese Medicine Powder and Medicine Innovation in Hunan (incubation), College of Medicine, Hunan University of Chinese Medicine, Changsha 410208, China.; Department of Medical Microbiology, Immunology & Cell Biology, Simmons Cancer Institute, Southern Illinois University School of Medicine. 913 N. Rutledge Street, Springfield, IL 62794, USA.
He L; Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, State Key Laboratory of Chinese Medicine Powder and Medicine Innovation in Hunan (incubation), College of Medicine, Hunan University of Chinese Medicine, Changsha 410208, China.
Khoshaba R; Department of Medical Microbiology, Immunology & Cell Biology, Simmons Cancer Institute, Southern Illinois University School of Medicine. 913 N. Rutledge Street, Springfield, IL 62794, USA.; Department of Biotechnology, College of Science, University of Baghdad, Baghdad 10011, Iraq.
Lu FG; Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, State Key Laboratory of Chinese Medicine Powder and Medicine Innovation in Hunan (incubation), College of Medicine, Hunan University of Chinese Medicine, Changsha 410208, China.
Cai C; Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, State Key Laboratory of Chinese Medicine Powder and Medicine Innovation in Hunan (incubation), College of Medicine, Hunan University of Chinese Medicine, Changsha 410208, China.
Zhou FL; Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, State Key Laboratory of Chinese Medicine Powder and Medicine Innovation in Hunan (incubation), College of Medicine, Hunan University of Chinese Medicine, Changsha 410208, China.
Liao DF; Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, State Key Laboratory of Chinese Medicine Powder and Medicine Innovation in Hunan (incubation), College of Medicine, Hunan University of Chinese Medicine, Changsha 410208, China.
Cao D; Department of Medical Microbiology, Immunology & Cell Biology, Simmons Cancer Institute, Southern Illinois University School of Medicine. 913 N. Rutledge Street, Springfield, IL 62794, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2019 Nov 18; Vol. 24 (22). Date of Electronic Publication: 2019 Nov 18.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Cell Cycle/*drug effects
Curcumin/*analogs & derivatives
Niacin/*analogs & derivatives
Tumor Suppressor Protein p53/*metabolism
Cell Proliferation/drug effects ; Curcumin/pharmacology ; Drug Screening Assays, Antitumor ; Gene Expression Regulation, Neoplastic ; HCT116 Cells ; Humans ; MCF-7 Cells ; Niacin/pharmacology
Czasopismo naukowe
Tytuł:
Curcumin diethyl disuccinate, a prodrug of curcumin, enhances anti-proliferative effect of curcumin against HepG2 cells via apoptosis induction.
Autorzy:
Muangnoi C; Pharmaceutical Chemistry and Natural Products Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.; Natural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand.
Ratnatilaka Na Bhuket P; Natural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand.
Jithavech P; Natural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand.
Supasena W; Natural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand.
Paraoan L; Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
Patumraj S; Center of Excellence for Microcirculation, Department of Physiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 10300, Thailand.
Rojsitthisak P; Natural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand. .; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, 10330, Thailand. .
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Źródło:
Scientific reports [Sci Rep] 2019 Aug 12; Vol. 9 (1), pp. 11718. Date of Electronic Publication: 2019 Aug 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Curcumin/*analogs & derivatives
Curcumin/*pharmacology
Prodrugs/*pharmacology
Succinates/*pharmacology
Antineoplastic Agents, Phytogenic/chemistry ; Apoptosis/genetics ; Biological Transport ; Caco-2 Cells ; Caspase 3/genetics ; Caspase 3/metabolism ; Caspase 9/genetics ; Caspase 9/metabolism ; Cell Survival/drug effects ; Curcumin/chemistry ; Hep G2 Cells ; Humans ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism ; Prodrugs/chemistry ; Proto-Oncogene Proteins c-bcl-2/antagonists & inhibitors ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Signal Transduction ; Succinates/chemistry ; bcl-2-Associated X Protein/agonists ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł:
Curcumin at Low Doses Potentiates and at High Doses Inhibits ABT-737-Induced Platelet Apoptosis.
Autorzy:
Rukoyatkina N; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 194223 St. Petersburg, Russia.
Shpakova V; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 194223 St. Petersburg, Russia.
Sudnitsyna J; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 194223 St. Petersburg, Russia.; Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, 109029 Moscow, Russia.
Panteleev M; Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, 109029 Moscow, Russia.
Makhoul S; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University of Mainz, 55131 Mainz, Germany.
Gambaryan S; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, 194223 St. Petersburg, Russia.; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University of Mainz, 55131 Mainz, Germany.
Jurk K; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University of Mainz, 55131 Mainz, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 May 20; Vol. 22 (10). Date of Electronic Publication: 2021 May 20.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Biphenyl Compounds/*pharmacology
Blood Platelets/*drug effects
Curcumin/*pharmacology
Nitrophenols/*pharmacology
Sulfonamides/*pharmacology
ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Adenosine Monophosphate/metabolism ; Blood Platelets/metabolism ; Curcuma/chemistry ; Drug Resistance, Multiple/drug effects ; Humans ; Piperazines/pharmacology ; Plant Extracts/pharmacology ; Platelet Aggregation Inhibitors/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł:
Curcumin Alleviates LPS-Induced Oxidative Stress, Inflammation and Apoptosis in Bovine Mammary Epithelial Cells via the NFE2L2 Signaling Pathway.
Autorzy:
Li R; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Fang H; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Shen J; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Jin Y; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Zhao Y; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Wang R; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Fu Y; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Tian Y; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Yu H; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
Zhang J; Key Laboratory of Zoonosis Research, Ministry of Education, Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China.
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Źródło:
Toxins [Toxins (Basel)] 2021 Mar 12; Vol. 13 (3). Date of Electronic Publication: 2021 Mar 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Apoptosis/*drug effects
Curcumin/*pharmacology
Endotoxins/*toxicity
Epithelial Cells/*drug effects
Inflammation Mediators/*metabolism
Mammary Glands, Animal/*drug effects
NF-E2-Related Factor 2/*metabolism
Oxidative Stress/*drug effects
Animals ; Apoptosis Regulatory Proteins/metabolism ; Cattle ; Cell Line ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Female ; Mammary Glands, Animal/metabolism ; Mammary Glands, Animal/pathology ; Reactive Oxygen Species/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
Induction of Apoptosis and Regulation of MicroRNA Expression by (2 E ,6 E )-2,6- bis -(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) Treatment on MCF-7 Breast Cancer Cells.
Autorzy:
Yeap SK; China-ASEAN College of Marine Sciences, Xiamen University Malaysia Campus, Jalan Sunsuria, Bandar Sunsuria, Sepang 43900, Selangor, Malaysia.
Mohd Ali N; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia, Serdang 43400, Selangor, Malaysia.; Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Sungai Long Campus, Jalan Sungai Long, Bandar Sungai Long, Cheras, Kajang 43000, Selangor, Malaysia.
Akhtar MN; Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak 26300, Kuantan Pahang, Malaysia.
Razak NA; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Chong ZX; School of Biomedical Sciences, The University of Nottingham Malaysia Campus, Jalan Broga, Semenyih 43500, Selangor, Malaysia.
Ho WY; School of Biomedical Sciences, The University of Nottingham Malaysia Campus, Jalan Broga, Semenyih 43500, Selangor, Malaysia.
Boo L; Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Sungai Long Campus, Jalan Sungai Long, Bandar Sungai Long, Cheras, Kajang 43000, Selangor, Malaysia.
Zareen S; Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak 26300, Kuantan Pahang, Malaysia.
Kurniawan TA; Key Laboratory of the Coastal and Wetland Ecosystems (Xiamen University), Ministry of Education, College of the Environment and Ecology, Xiamen University, Fujian 361102, China.
Avtar R; Faculty of Environmental Earth Sciences, Hokkaido University, Sapporo 060-0810, Japan.
Ng SYL; China-ASEAN College of Marine Sciences, Xiamen University Malaysia Campus, Jalan Sunsuria, Bandar Sunsuria, Sepang 43900, Selangor, Malaysia.
Ong AHK; Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Sungai Long Campus, Jalan Sungai Long, Bandar Sungai Long, Cheras, Kajang 43000, Selangor, Malaysia.
Alitheen NB; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia, Serdang 43400, Selangor, Malaysia.; UPM-MAKNA Cancer Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Feb 26; Vol. 26 (5). Date of Electronic Publication: 2021 Feb 26.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Breast Neoplasms/*drug therapy
Cell Proliferation/*drug effects
MicroRNAs/*genetics
Antineoplastic Agents/pharmacology ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Curcumin/analogs & derivatives ; Curcumin/pharmacology ; Cyclohexanones/pharmacology ; Female ; G2 Phase Cell Cycle Checkpoints/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; MCF-7 Cells
Czasopismo naukowe
Tytuł:
Chemoprotective effects of curcumin on doxorubicin-induced nephrotoxicity in wistar rats: by modulating inflammatory cytokines, apoptosis, oxidative stress and oxidative DNA damage.
Autorzy:
Benzer F; a Department of Food Engineering, Faculty of Engineering , Munzur University , Tunceli , Turkey.
Kandemir FM; b Department of Biochemistry, Faculty of Veterinary Medicine , Ataturk University , Erzurum , Turkey.
Kucukler S; b Department of Biochemistry, Faculty of Veterinary Medicine , Ataturk University , Erzurum , Turkey.
Comaklı S; c Department of Pathology, Faculty of Veterinary Medicine , Ataturk University , Erzurum , Turkey.
Caglayan C; d Department of Biochemistry, Faculty of Veterinary Medicine , Bingol University , Bingol , Turkey.
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Źródło:
Archives of physiology and biochemistry [Arch Physiol Biochem] 2018 Dec; Vol. 124 (5), pp. 448-457. Date of Electronic Publication: 2018 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*drug effects
Curcumin/*therapeutic use
Doxorubicin/*antagonists & inhibitors
Kidney/*drug effects
Oxidative Stress/*drug effects
Protective Agents/*therapeutic use
Renal Insufficiency/*prevention & control
Animals ; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage ; Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Antibiotics, Antineoplastic/adverse effects ; Antibiotics, Antineoplastic/chemistry ; Antioxidants/administration & dosage ; Antioxidants/adverse effects ; Antioxidants/therapeutic use ; Biomarkers/blood ; Biomarkers/metabolism ; Curcumin/administration & dosage ; Curcumin/adverse effects ; Cyclooxygenase 2/chemistry ; Cyclooxygenase 2/metabolism ; DNA Damage/drug effects ; Dose-Response Relationship, Drug ; Doxorubicin/adverse effects ; Kidney/immunology ; Kidney/metabolism ; Kidney/pathology ; Lipid Peroxidation/drug effects ; Male ; Nitric Oxide Synthase Type II/antagonists & inhibitors ; Nitric Oxide Synthase Type II/metabolism ; Oxidation-Reduction ; Protective Agents/administration & dosage ; Protective Agents/adverse effects ; Random Allocation ; Rats, Wistar ; Renal Insufficiency/chemically induced ; Renal Insufficiency/immunology ; Renal Insufficiency/metabolism ; Topoisomerase II Inhibitors/adverse effects ; Topoisomerase II Inhibitors/chemistry
Czasopismo naukowe
Tytuł:
Combinatorial effect of curcumin and tumor necrosis factor-α-related apoptosis-inducing ligand (TRAIL) in induction of apoptosis via inhibition of nuclear factor kappa activity and enhancement of caspase-3 activity in chronic myeloid cells: An In-vitro study.
Autorzy:
Iqbal B; Department of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Ghildiyal A; Department of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Singh S; Department of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Siddiqui S; Department of Biotechnology, Era's Lucknow Medical College & Hospital, Era University, Lucknow, Uttar Pradesh, India.
Kumari P; Department of Obstetrics and Gynaecology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Arshad M; Department of Zoology, Lucknow University, Lucknow, Uttar Pradesh, India.
Mahdi AA; Department of Biochemistry, King George's Medical University, Lucknow, Uttar Pradesh, India.
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Źródło:
Journal of cancer research and therapeutics [J Cancer Res Ther] 2018 Dec; Vol. 14 (Supplement), pp. S1193-S1200.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Apoptosis/*drug effects
Caspase 3/*metabolism
Curcumin/*pharmacology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
NF-kappa B p50 Subunit/*metabolism
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cell Line, Tumor ; Cell Nucleus ; Cell Survival/drug effects ; Curcumin/therapeutic use ; Drug Synergism ; Humans ; I-kappa B Kinase/metabolism ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Mitochondria ; NF-kappa B p50 Subunit/antagonists & inhibitors ; TNF-Related Apoptosis-Inducing Ligand/therapeutic use
Czasopismo naukowe
Tytuł:
Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells.
Autorzy:
Man S; State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Key Laboratory of Industry Microbiology, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, China.
Zhang L; State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Key Laboratory of Industry Microbiology, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, China.
Cui J; State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Key Laboratory of Industry Microbiology, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, China.
Yang L; State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Key Laboratory of Industry Microbiology, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, China.
Ma L; State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology, Ministry of Education, Tianjin Key Laboratory of Industry Microbiology, College of Biotechnology, Tianjin University of Science & Technology, Tianjin, China.
Gao W; Tianjin Key Laboratory for Modern Drug Delivery and High Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, China.
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Źródło:
Cell proliferation [Cell Prolif] 2018 Aug; Vol. 51 (4), pp. e12458. Date of Electronic Publication: 2018 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/drug effects
Antineoplastic Agents/*pharmacology
Curcumin/*pharmacology
Diosgenin/*analogs & derivatives
Saponins/*pharmacology
Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Curcumin/chemistry ; Diosgenin/chemistry ; Diosgenin/pharmacology ; Drug Synergism ; Fas Ligand Protein/genetics ; Fas Ligand Protein/metabolism ; G2 Phase Cell Cycle Checkpoints/drug effects ; Humans ; Insulin-Like Growth Factor Binding Protein 1/metabolism ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; NF-kappa B/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Tumor Necrosis Factor/genetics ; Receptors, Tumor Necrosis Factor/metabolism ; Saponins/chemistry ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
Demethoxycurcumin-Loaded Chitosan Nanoparticle Downregulates DNA Repair Pathway to Improve Cisplatin-Induced Apoptosis in Non-Small Cell Lung Cancer.
Autorzy:
Chen YY; School of Pharmacy, China Medical University, Hsueh-Hsih Road, Taichung 40402, Taiwan. .
Lin YJ; Department of Pharmacy, Chang Bing Show Chwan Memorial Hospital, No.6, Lugong Rd. Lugang Town, Changhua County 505, Taiwan. .
Huang WT; Department of Materials Science and Engineering, National Chiao Tung University, 1001 University Road, Hsinchu 300, Taiwan. .
Hung CC; School of Pharmacy, China Medical University, Hsueh-Hsih Road, Taichung 40402, Taiwan. .
Lin HY; School of Pharmacy, China Medical University, Hsueh-Hsih Road, Taichung 40402, Taiwan. .
Tu YC; School of Pharmacy, China Medical University, Hsueh-Hsih Road, Taichung 40402, Taiwan. .
Liu DM; Department of Materials Science and Engineering, National Chiao Tung University, 1001 University Road, Hsinchu 300, Taiwan. .
Lan SJ; Department of Healthcare Administration, Asia University, Taichung 41354, Taiwan. .
Sheu MJ; School of Pharmacy, China Medical University, Hsueh-Hsih Road, Taichung 40402, Taiwan. .
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2018 Dec 05; Vol. 23 (12). Date of Electronic Publication: 2018 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
Chitosan*/chemistry
Nanoparticles*/chemistry
Nanoparticles*/ultrastructure
Antineoplastic Agents/*administration & dosage
Apoptosis/*drug effects
Carcinoma, Non-Small-Cell Lung/*genetics
Curcumin/*analogs & derivatives
Lung Neoplasms/*genetics
Carcinoma, Non-Small-Cell Lung/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Cisplatin/pharmacology ; Curcumin/administration & dosage ; Diarylheptanoids ; Drug Resistance, Neoplasm/drug effects ; Humans ; Lung Neoplasms/metabolism ; Microscopy, Confocal ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł:
Topically applicated curcumin/gelatin-blended nanofibrous mat inhibits pancreatic adenocarcinoma by increasing ROS production and endoplasmic reticulum stress mediated apoptosis.
Autorzy:
Cheng T; Department of General Surgery, Zhongda Hospital, Medical School, Southeast University, Nanjing, 210000, China.
Zhang Z; Department of Surgery, Klinikum Rechts Der Isar, School of Medicine, Technical University of Munich, 81675, Munich, Germany.
Shen H; Department of Plastic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Jian Z; Department of Hematology and Oncology, Zhongda Hospital, Medical School, Southeast University, Nanjing, 21000, China.
Li J; Department of General Surgery, Zhongda Hospital, Medical School, Southeast University, Nanjing, 210000, China.
Chen Y; Bio-ID Center, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Shen Y; Bio-ID Center, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China. .
Dai X; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, 200011, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2020 Sep 05; Vol. 18 (1), pp. 126. Date of Electronic Publication: 2020 Sep 05.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma/*drug therapy
Apoptosis/*drug effects
Curcumin/*pharmacology
Endoplasmic Reticulum Stress/*drug effects
Gelatin/*pharmacology
Nanofibers/*chemistry
Pancreatic Neoplasms/*drug therapy
Reactive Oxygen Species/*metabolism
Adenocarcinoma/pathology ; Animals ; Antineoplastic Agents/pharmacology ; Biological Availability ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Humans ; Mice ; Pancreatic Neoplasms/pathology ; X-Ray Diffraction ; Xenograft Model Antitumor Assays ; Pancreatic Neoplasms
Czasopismo naukowe
Tytuł:
DK1 Induces Apoptosis via Mitochondria-Dependent Signaling Pathway in Human Colon Carcinoma Cell Lines In Vitro.
Autorzy:
Hussin Y; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia. .
Aziz MNM; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia. .
Che Rahim NF; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia. .
Yeap SK; China-ASEAN College of Marine Science, Xiamen University Malaysia, Sepang 43900, Malaysia. .
Mohamad NE; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia. .
Masarudin MJ; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia. .
Nordin N; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia. .
Abd Rahman NMA; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia. .
Yong CY; Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia. .
Akhtar MN; Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, Kuantan 26300, Malaysia. .
Zamrus SNH; Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, Kuantan 26300, Malaysia. .
Alitheen NB; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Malaysia. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2018 Apr 11; Vol. 19 (4). Date of Electronic Publication: 2018 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Carcinoma/*metabolism
Colonic Neoplasms/*metabolism
Curcumin/*analogs & derivatives
Curcumin/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Curcumin/chemical synthesis ; Curcumin/chemistry ; HT29 Cells ; Humans ; Mitochondria/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
Anti-tumour effects of TRAIL-expressing human placental derived mesenchymal stem cells with curcumin-loaded chitosan nanoparticles in a mice model of triple negative breast cancer.
Autorzy:
Kamalabadi-Farahani M; a Department of Tissue Engineering and Applied Cell Sciences, Faculty of Advanced Technologies in Medicine , Tehran University of Medical Sciences (TUMS) , Tehran , Iran.
Vasei M; b Department of Pathology, Molecular and Cell Biology Laboratory , Shariati Hospital, Tehran University of Medical Sciences (TUMS) , Tehran , Iran.
Ahmadbeigi N; c Cell Based Therapies Research Center, Digestive Disease Research Institute , Tehran University of Medical Sciences (TUMS) , Tehran , Iran.
Ebrahimi-Barough S; a Department of Tissue Engineering and Applied Cell Sciences, Faculty of Advanced Technologies in Medicine , Tehran University of Medical Sciences (TUMS) , Tehran , Iran.
Soleimani M; d Department of Hematology , Tarbiat Modares University , Tehran , Iran.
Roozafzoon R; a Department of Tissue Engineering and Applied Cell Sciences, Faculty of Advanced Technologies in Medicine , Tehran University of Medical Sciences (TUMS) , Tehran , Iran.
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Źródło:
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2018; Vol. 46 (sup3), pp. S1011-S1021. Date of Electronic Publication: 2018 Dec 24.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Chitosan*/chemistry
Chitosan*/pharmacology
Curcumin*/chemistry
Curcumin*/pharmacology
Triple Negative Breast Neoplasms*/pathology
Triple Negative Breast Neoplasms*/therapy
Mesenchymal Stem Cells/*metabolism
Nanoparticles/*chemistry
Placenta/*metabolism
TNF-Related Apoptosis-Inducing Ligand/*metabolism
Animals ; Cell Line, Tumor ; Female ; Humans ; Mesenchymal Stem Cells/pathology ; Mice ; Placenta/pathology ; Pregnancy
Czasopismo naukowe
Tytuł:
Effects of demethoxycurcumin on the viability and apoptosis of skin cancer cells.
Autorzy:
Wu Y; Department of Dermatology, Xiangyang Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China.
Zhang P; Department of Radiotherapy, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, P.R. China.
Yang H; Department of Dermatology, Xiangyang Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China.
Ge Y; Department of Clinical Laboratory, Xiangyang Central Hospital, Hubei University of Arts and Science, Xiangyang, Hubei 441000, P.R. China.
Xin Y; Department of Radiotherapy, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221002, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2017 Jul; Vol. 16 (1), pp. 539-546. Date of Electronic Publication: 2017 May 31.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Curcumin/*analogs & derivatives
Antineoplastic Agents/chemistry ; Caspase 3/metabolism ; Caspase 9/metabolism ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Curcumin/chemistry ; Curcumin/pharmacology ; Cytochromes c/genetics ; Cytochromes c/metabolism ; Diarylheptanoids ; Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Skin Neoplasms/metabolism ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe

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