Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""CX3C Chemokine Receptor 1"" wg kryterium: Temat


Tytuł :
CX3CR1 positively regulates BCR signaling coupled with cell metabolism via negatively controlling actin remodeling.
Autorzy :
Li N; Clinical Molecular Immunology Center, Department of Immunology, School of Medicine, Yangtze University, Jingzhou, 434023, China.
Jiang P; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Chen A; Chongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, 400016, China.
Luo X; The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education and Chinese Academy of Medical Sciences, NHC Key Laboratory of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Jing Y; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Yang L; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Kang D; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Chen Q; Clinical Molecular Immunology Center, Department of Immunology, School of Medicine, Yangtze University, Jingzhou, 434023, China.
Liu J; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Chang J; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Jellusova J; BIOSS Centre for Biological Signalling Studies, Albert Ludwigs University of Freiburg, 79104, Freiburg Im Breisgau, Baden-Württemberg, Germany.
Miller H; Department of Intracellular Pathogens, National Institute of Allergy and Infectious Diseases, Bethesda, MT, 59840, USA.
Westerberg L; Department of Microbiology Tumor and Cell Biology, KarolinskaInstitutet, Stockholm, 17177, Sweden.
Wang CY; The Center for Biomedical Research, Key Laboratory of Organ Transplantation, Ministry of Education and Chinese Academy of Medical Sciences, NHC Key Laboratory of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Gong Q; Clinical Molecular Immunology Center, Department of Immunology, School of Medicine, Yangtze University, Jingzhou, 434023, China. .
Liu C; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. .
Pokaż więcej
Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Nov; Vol. 77 (21), pp. 4379-4395. Date of Electronic Publication: 2020 Feb 04.
Typ publikacji :
Journal Article
MeSH Terms :
Actins/*metabolism
B-Lymphocytes/*cytology
CX3C Chemokine Receptor 1/*metabolism
Receptors, Antigen, B-Cell/*metabolism
Animals ; B-Lymphocytes/metabolism ; CX3C Chemokine Receptor 1/genetics ; Cell Differentiation ; Mice, Inbred C57BL ; Mice, Knockout ; Signal Transduction
Czasopismo naukowe
Tytuł :
Evaluation of the respiratory syncytial virus G-directed neutralizing antibody response in the human airway epithelial cell model.
Autorzy :
Kishko M; Sanofi Pasteur, Cambridge, MA, USA.
Catalan J; Sanofi Pasteur, Cambridge, MA, USA.
Swanson K; Sanofi, Cambridge, MA, USA.
DiNapoli J; Sanofi Pasteur, Cambridge, MA, USA.
Wei CJ; Sanofi, Cambridge, MA, USA.
Delagrave S; Sanofi Pasteur, Cambridge, MA, USA.
Chivukula S; Sanofi Pasteur, Cambridge, MA, USA.
Zhang L; Sanofi Pasteur, Cambridge, MA, USA. Electronic address: .
Pokaż więcej
Źródło :
Virology [Virology] 2020 Nov; Vol. 550, pp. 21-26. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Neutralizing/*biosynthesis
Antibodies, Viral/*biosynthesis
Antigens, Viral/*immunology
CX3C Chemokine Receptor 1/*immunology
Respiratory Syncytial Virus, Human/*immunology
Viral Fusion Proteins/*immunology
Animals ; Antigens, Viral/administration & dosage ; Antigens, Viral/genetics ; CX3C Chemokine Receptor 1/genetics ; Chlorocebus aethiops ; Epithelial Cells/immunology ; Epithelial Cells/virology ; Female ; Gene Expression ; Humans ; Immune Sera/chemistry ; Immunization ; Mice ; Mice, Inbred BALB C ; Models, Biological ; Neutralization Tests ; Protein Binding ; Receptors, Virus/genetics ; Receptors, Virus/immunology ; Respiratory Mucosa/immunology ; Respiratory Mucosa/virology ; Respiratory Syncytial Virus Infections/immunology ; Respiratory Syncytial Virus Infections/virology ; Respiratory Syncytial Virus, Human/genetics ; Respiratory Syncytial Virus, Human/pathogenicity ; Vero Cells ; Viral Fusion Proteins/administration & dosage ; Viral Fusion Proteins/genetics
Czasopismo naukowe
Tytuł :
The CX3CL1/CX3CR1 axis is upregulated in chronic kidney disease and contributes to angiotensin II-induced migration of vascular smooth muscle cells.
Autorzy :
Li C; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Zhong X; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Xia W; Class 4, Grade 2, Guangzhou Zhixin High School, Guangzhou 511430, China.
He J; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Gan H; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Zhao H; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. Electronic address: .
Xia Y; Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. Electronic address: .
Pokaż więcej
Źródło :
Microvascular research [Microvasc Res] 2020 Nov; Vol. 132, pp. 104037. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin II/*pharmacology
CX3C Chemokine Receptor 1/*metabolism
Cell Movement/*drug effects
Chemokine CX3CL1/*metabolism
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Renal Insufficiency, Chronic/*metabolism
Uremia/*metabolism
Animals ; Aorta/drug effects ; Aorta/metabolism ; Aorta/pathology ; CX3C Chemokine Receptor 1/genetics ; Cell Line ; Chemokine CX3CL1/genetics ; Disease Models, Animal ; Interleukin-6/metabolism ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/metabolism ; Myocytes, Smooth Muscle/pathology ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Renal Insufficiency, Chronic/pathology ; Signal Transduction ; Up-Regulation ; Uremia/pathology
Czasopismo naukowe
Tytuł :
Inhibition of CX3C receptor 1-mediated autophagy in macrophages alleviates pulmonary fibrosis in hyperoxic lung injury.
Autorzy :
Chen Y; Department of Respiratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai 200080, China. Electronic address: .
Zhang H; Department of Respiratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai 200080, China.
Li F; Department of Respiratory, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai 200080, China.
Wang X; Department of Clinical Pharmacology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 100 Haining Road, Shanghai 200080, China.
Pokaż więcej
Źródło :
Life sciences [Life Sci] 2020 Oct 15; Vol. 259, pp. 118286. Date of Electronic Publication: 2020 Aug 15.
Typ publikacji :
Journal Article
MeSH Terms :
CX3C Chemokine Receptor 1/*metabolism
Hyperoxia/*metabolism
Lung Injury/*metabolism
Pulmonary Fibrosis/*metabolism
Animals ; Autophagy/physiology ; Blotting, Western ; CX3C Chemokine Receptor 1/antagonists & inhibitors ; Disease Models, Animal ; Hyperoxia/pathology ; Lung/metabolism ; Lung Injury/pathology ; Macrophages/metabolism ; Macrophages/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Pulmonary Fibrosis/pathology
Czasopismo naukowe
Tytuł :
CX3CR1 Deficiency Attenuates DNFB-Induced Contact Hypersensitivity Through Skewed Polarization Towards M2 Phenotype in Macrophages.
Autorzy :
Otobe S; Department of Dermatology, the University of Tokyo Graduate School of Medicine, Tokyo 113-8655, Japan.
Hisamoto T; Department of Dermatology, the University of Tokyo Graduate School of Medicine, Tokyo 113-8655, Japan.
Miyagaki T; Department of Dermatology, the University of Tokyo Graduate School of Medicine, Tokyo 113-8655, Japan.; Department of Dermatology, St. Marianna University School of Medicine, Kanagawa 216-8511, Japan.
Morimura S; Department of Dermatology, the University of Tokyo Graduate School of Medicine, Tokyo 113-8655, Japan.; Department of Dermatology, International University of Health and Welfare, Chiba 286-0124, Japan.
Suga H; Department of Dermatology, the University of Tokyo Graduate School of Medicine, Tokyo 113-8655, Japan.
Sugaya M; Department of Dermatology, the University of Tokyo Graduate School of Medicine, Tokyo 113-8655, Japan.; Department of Dermatology, International University of Health and Welfare, Chiba 286-0124, Japan.
Sato S; Department of Dermatology, the University of Tokyo Graduate School of Medicine, Tokyo 113-8655, Japan.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 07; Vol. 21 (19). Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article
MeSH Terms :
CX3C Chemokine Receptor 1/*deficiency
Dermatitis, Contact/*etiology
Dermatitis, Contact/*metabolism
Dinitrofluorobenzene/*pharmacology
Macrophage Activation/*drug effects
Macrophage Activation/*immunology
Macrophages/*drug effects
Macrophages/*physiology
Animals ; Biomarkers ; CX3C Chemokine Receptor 1/metabolism ; Dermatitis, Contact/pathology ; Disease Models, Animal ; Disease Susceptibility ; Immunohistochemistry ; Mice ; Mice, Knockout ; Neutrophil Infiltration/immunology
Czasopismo naukowe
Tytuł :
MMP-9 regulates CX3CL1/CX3CR1 in the early phase of neuropathic pain in chronic sciatic nerve constriction injury (CCI) rats.
Autorzy :
Zhao L; Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Song C; Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huang Y; Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Lei W; Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Sun J; Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China. .
Pokaż więcej
Źródło :
Annals of palliative medicine [Ann Palliat Med] 2020 Jul; Vol. 9 (4), pp. 2020-2027. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article
MeSH Terms :
CX3C Chemokine Receptor 1*/metabolism
Chemokine CX3CL1*/metabolism
Matrix Metalloproteinase 9*/genetics
Neuralgia*
Sciatic Nerve*/injuries
Animals ; Constriction ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Revising CX3CR1 Expression on Murine Classical and Non-classical Monocytes.
Autorzy :
Meghraoui-Kheddar A; Sorbonne Université, Inserm, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.; Université Côte d'Azur, CNRS UMR7275, Institut de Pharmacologie Moléculaire et Cellulaire (IPMC), Valbonne, France.
Barthelemy S; Sorbonne Université, Inserm, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.
Boissonnas A; Sorbonne Université, Inserm, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.
Combadière C; Sorbonne Université, Inserm, CNRS, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, Paris, France.
Pokaż więcej
Źródło :
Frontiers in immunology [Front Immunol] 2020 Jun 03; Vol. 11, pp. 1117. Date of Electronic Publication: 2020 Jun 03 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CX3C Chemokine Receptor 1/*immunology
Monocytes/*cytology
Monocytes/*immunology
Animals ; CX3C Chemokine Receptor 1/metabolism ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
CX3CR1-Targeted PLGA Nanoparticles Reduce Microglia Activation and Pain Behavior in Rats with Spinal Nerve Ligation.
Autorzy :
Noh C; Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Shin HJ; Department of Medical Science, 3 Department of Anatomy and Cell Biology, 4 Brain Research Institute, School of medicine, Chungnam National University, Daejeon 35015, Korea.
Lee S; Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Kim SI; Department of Medical Science, 3 Department of Anatomy and Cell Biology, 4 Brain Research Institute, School of medicine, Chungnam National University, Daejeon 35015, Korea.
Kim YH; Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Lee WH; Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Kim DW; Department of Medical Science, 3 Department of Anatomy and Cell Biology, 4 Brain Research Institute, School of medicine, Chungnam National University, Daejeon 35015, Korea.
Lee SY; Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Ko YK; Department of Anesthesiology and Pain Medicine, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 May 14; Vol. 21 (10). Date of Electronic Publication: 2020 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
CX3C Chemokine Receptor 1/*genetics
Nanoparticles/*chemistry
Neuralgia/*drug therapy
RNA, Small Interfering/*pharmacology
Spinal Nerves/*drug effects
Animals ; Behavior, Animal/drug effects ; CX3C Chemokine Receptor 1/antagonists & inhibitors ; Humans ; Ligation ; Lipopolysaccharides/pharmacology ; Macrophage Activation/drug effects ; Microglia/drug effects ; Neuralgia/genetics ; Neuralgia/pathology ; Pain Management ; Pain Measurement/methods ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Polylactic Acid-Polyglycolic Acid Copolymer/pharmacology ; RNA, Small Interfering/genetics ; Rats ; Spinal Cord/drug effects ; Spinal Cord/pathology ; Spinal Cord Dorsal Horn/drug effects ; Spinal Cord Dorsal Horn/pathology ; Spinal Nerves/metabolism ; Spinal Nerves/pathology
Czasopismo naukowe
Tytuł :
Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the expression of Cx3cr1 .
Autorzy :
Madel MB; Laboratoire de PhysioMédecine Moléculaire, CNRS, Nice, France.; Université Côte d'Azur, Nice, France.
Ibáñez L; Department of Pharmacy, Cardenal Herrera-CEU University, Valencia, Spain.
Ciucci T; Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, United States.
Halper J; Laboratoire de PhysioMédecine Moléculaire, CNRS, Nice, France.; Université Côte d'Azur, Nice, France.
Rouleau M; Laboratoire de PhysioMédecine Moléculaire, CNRS, Nice, France.; Université Côte d'Azur, Nice, France.
Boutin A; Laboratoire de PhysioMédecine Moléculaire, CNRS, Nice, France.; Université Côte d'Azur, Nice, France.
Hue C; Université Paris-Saclay, UVSQ, INSERM, Infection et inflammation, Montigny-Le-Bretonneux, France.
Duroux-Richard I; IRMB, Univ Montpellier, INSERM, CHU Montpellier, Montpellier, France.
Apparailly F; IRMB, Univ Montpellier, INSERM, CHU Montpellier, Montpellier, France.
Garchon HJ; Université Paris-Saclay, UVSQ, INSERM, Infection et inflammation, Montigny-Le-Bretonneux, France.; Genetics division, Ambroise Paré Hospital, AP-HP, Boulogne-Billancourt, France.
Wakkach A; Laboratoire de PhysioMédecine Moléculaire, CNRS, Nice, France.; Université Côte d'Azur, Nice, France.
Blin-Wakkach C; Laboratoire de PhysioMédecine Moléculaire, CNRS, Nice, France.; Université Côte d'Azur, Nice, France.
Pokaż więcej
Źródło :
ELife [Elife] 2020 May 13; Vol. 9. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Osteogenesis*
Bone Resorption/*metabolism
CX3C Chemokine Receptor 1/*metabolism
Inflammation/*metabolism
Osteoclasts/*metabolism
Osteoporosis/*metabolism
Animals ; Bone Resorption/immunology ; Bone Resorption/pathology ; Bone Resorption/prevention & control ; CX3C Chemokine Receptor 1/genetics ; Cell Communication ; Cells, Cultured ; Female ; Inflammation/immunology ; Inflammation/pathology ; Inflammation/prevention & control ; Mice, Inbred C57BL ; Mice, Knockout ; Osteoclasts/immunology ; Osteoclasts/pathology ; Osteoporosis/immunology ; Osteoporosis/pathology ; Osteoporosis/prevention & control ; Ovariectomy ; Phenotype ; Signal Transduction ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice.
Autorzy :
Song Q; Diabetes and Metabolism Research Institute, The Beckman Research Institute of City of Hope, Duarte, CA, USA.; Hematologic Malignancies and Stem Cell Transplantation Institute, The Beckman Research Institute of City of Hope, Duarte, CA, USA.; Fujian Medical University Center of Translational Hematology, Fujian Institute of Hematology, and Fujian Medical University Union Hospital, Fuzhou, China.
Wang X; Diabetes and Metabolism Research Institute, The Beckman Research Institute of City of Hope, Duarte, CA, USA.; Hematologic Malignancies and Stem Cell Transplantation Institute, The Beckman Research Institute of City of Hope, Duarte, CA, USA.; Department of Hematology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Wu X; Department of Integrative Genomics Core, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Kang TH; Department of Integrative Genomics Core, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Qin H; Department of Integrative Genomics Core, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Zhao D; The Tisch Cancer Institute and Division of Hematology/Medical Oncology, The Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA.
Jenq RR; Departments of Genomic Medicine and Stem Cell Transplantation Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
van den Brink MRM; Department of Medicine, Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Riggs AD; Diabetes and Metabolism Research Institute, The Beckman Research Institute of City of Hope, Duarte, CA, USA.
Martin PJ; Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA, USA.
Chen YZ; Fujian Medical University Center of Translational Hematology, Fujian Institute of Hematology, and Fujian Medical University Union Hospital, Fuzhou, China. .
Zeng D; Diabetes and Metabolism Research Institute, The Beckman Research Institute of City of Hope, Duarte, CA, USA. .; Hematologic Malignancies and Stem Cell Transplantation Institute, The Beckman Research Institute of City of Hope, Duarte, CA, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Feb 05; Vol. 12 (1), pp. 805. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
CD8-Positive T-Lymphocytes/*immunology
Dysbiosis/*immunology
Graft vs Host Disease/*immunology
Interferon-gamma/*immunology
Interleukins/*immunology
Phagocytes/*immunology
Animals ; CD8-Positive T-Lymphocytes/pathology ; CD8-Positive T-Lymphocytes/transplantation ; CX3C Chemokine Receptor 1/genetics ; CX3C Chemokine Receptor 1/immunology ; Disease Models, Animal ; Dysbiosis/genetics ; Dysbiosis/microbiology ; Dysbiosis/pathology ; Gastrointestinal Microbiome/immunology ; Gene Expression Regulation ; Graft vs Host Disease/genetics ; Graft vs Host Disease/microbiology ; Graft vs Host Disease/pathology ; Interferon-gamma/deficiency ; Interferon-gamma/genetics ; Interleukin-17/deficiency ; Interleukin-17/genetics ; Interleukin-17/immunology ; Interleukins/genetics ; Intestines/immunology ; Intestines/microbiology ; Intestines/pathology ; Lymphocyte Depletion ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Pancreatitis-Associated Proteins/genetics ; Pancreatitis-Associated Proteins/immunology ; Phagocytes/cytology ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/immunology ; Signal Transduction ; T-Lymphocytes, Helper-Inducer ; T-Lymphocytes, Regulatory ; Whole-Body Irradiation
Czasopismo naukowe
Tytuł :
Distinct Effects of Escherichia coli, Pseudomonas aeruginosa Cell Wall Component-Induced Inflammation on the Iron Metabolism of THP-1 Cells.Staphylococcus aureus Cell Wall Component-Induced Inflammation on the Iron Metabolism of THP-1 Cells.
Autorzy :
Pandur E; Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.
Tamási K; Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.
Pap R; Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.
Jánosa G; Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.
Sipos K; Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Pécs, Rókus Str. 2., H-7624 Pécs, Hungary.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 02; Vol. 22 (3). Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Wall/*chemistry
Cytokines/*metabolism
Escherichia coli/*chemistry
Iron/*metabolism
Lipopolysaccharides/*pharmacology
Pseudomonas aeruginosa/*chemistry
Staphylococcus aureus/*chemistry
THP-1 Cells/*metabolism
Teichoic Acids/*pharmacology
Biological Transport ; CX3C Chemokine Receptor 1/biosynthesis ; CX3C Chemokine Receptor 1/genetics ; Chemokine CX3CL1/metabolism ; Cytokines/biosynthesis ; Cytosol/metabolism ; Ferritins/biosynthesis ; Ferritins/genetics ; Heme Oxygenase-1/biosynthesis ; Heme Oxygenase-1/genetics ; Hepcidins/biosynthesis ; Hepcidins/genetics ; Humans ; Mitochondria/metabolism ; Neoplasm Proteins/biosynthesis ; Neoplasm Proteins/genetics ; Oxidoreductases/biosynthesis ; Oxidoreductases/genetics ; RNA, Messenger/biosynthesis ; RNA, Neoplasm/genetics ; THP-1 Cells/drug effects
Czasopismo naukowe
Tytuł :
T-cell CX3CR1 expression as a dynamic blood-based biomarker of response to immune checkpoint inhibitors.
Autorzy :
Yamauchi T; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Hoki T; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; Merck Sharp & Dohme, Tokyo, Japan.
Oba T; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Jain V; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Chen H; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; Department of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, NY, USA.
Attwood K; Department of Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Battaglia S; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
George S; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; Department of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, NY, USA.
Chatta G; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Puzanov I; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Morrison C; Department of Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Odunsi K; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; Department of Gynecologic Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; University of Chicago Comprehensive Cancer Center, Chicago, IL, USA.
Segal BH; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; Department of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, NY, USA.; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Dy GK; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Ernstoff MS; Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.; Department of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, NY, USA.; Division of Cancer Treatment and Diagnosis, Developmental Therapeutics Program, National Cancer Institute, Bethesda, MD, USA.
Ito F; Center for Immunotherapy, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. .; Department of Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. .; Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA. .; Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, NY, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Mar 03; Vol. 12 (1), pp. 1402. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Biomarkers, Pharmacological/*blood
CX3C Chemokine Receptor 1/*blood
Carcinoma, Non-Small-Cell Lung/*drug therapy
Immune Checkpoint Inhibitors/*pharmacology
Lung Neoplasms/*drug therapy
Aged ; Aged, 80 and over ; Animals ; Antibodies, Monoclonal, Humanized/pharmacology ; CD8-Positive T-Lymphocytes/drug effects ; CD8-Positive T-Lymphocytes/physiology ; Carcinoma, Non-Small-Cell Lung/immunology ; Carcinoma, Non-Small-Cell Lung/mortality ; Cell Line, Tumor ; Female ; Humans ; Ki-67 Antigen/blood ; Lung Neoplasms/immunology ; Lung Neoplasms/mortality ; Lymphocytes, Tumor-Infiltrating/drug effects ; Male ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Middle Aged ; Neoplasms, Experimental/blood supply ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/immunology ; Nivolumab/pharmacology ; Receptors, Antigen, T-Cell/metabolism ; Survival Rate ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Dual-Functionalized MSCs that Express CX3CR1 and IL-25 Exhibit Enhanced Therapeutic Effects on Inflammatory Bowel Disease.
Autorzy :
Fu Y; State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing 210023, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Ni J; State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing 210023, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Chen J; State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing 210023, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Ma G; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Zhao M; State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing 210023, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Zhu S; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Shi T; State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing 210023, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Zhu J; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Huang Z; State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing 210023, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China. Electronic address: .
Zhang J; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China. Electronic address: .
Chen J; State Key Laboratory of Analytical Chemistry for Life Science, School of Life Sciences, Nanjing University, Nanjing 210023, China; State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China. Electronic address: .
Pokaż więcej
Źródło :
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2020 Apr 08; Vol. 28 (4), pp. 1214-1228. Date of Electronic Publication: 2020 Jan 21.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CX3C Chemokine Receptor 1/*genetics
Colitis/*therapy
Interleukins/*genetics
Lentivirus/*genetics
Mesenchymal Stem Cells/*metabolism
Animals ; CX3C Chemokine Receptor 1/metabolism ; Colitis/chemically induced ; Colitis/metabolism ; Disease Models, Animal ; Female ; Interleukins/metabolism ; Mesenchymal Stem Cell Transplantation ; Mesenchymal Stem Cells/virology ; Mice ; Rats ; Sodium Dodecyl Sulfate/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Visceral adipose NLRP3 impairs cognition in obesity via IL-1R1 on CX3CR1+ cells.
Autorzy :
Guo DH; Department of Neuroscience and Regenerative Medicine.
Yamamoto M; Department of Neuroscience and Regenerative Medicine.
Hernandez CM; Department of Pharmacology and Toxicology.
Khodadadi H; Department of Oral Biology, and.
Baban B; Department of Oral Biology, and.; Plastic Surgery Section, Department of Surgery, Medical College of Georgia, Augusta University, Augusta, Georgia, USA.
Stranahan AM; Department of Neuroscience and Regenerative Medicine.
Pokaż więcej
Źródło :
The Journal of clinical investigation [J Clin Invest] 2020 Apr 01; Vol. 130 (4), pp. 1961-1976.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cognition*
CX3C Chemokine Receptor 1/*metabolism
Hippocampus/*metabolism
Intra-Abdominal Fat/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Obesity/*metabolism
Receptors, Interleukin-1 Type I/*metabolism
Animals ; CX3C Chemokine Receptor 1/genetics ; Hippocampus/pathology ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Intra-Abdominal Fat/pathology ; Intra-Abdominal Fat/transplantation ; Mice ; Mice, Knockout ; Microglia/metabolism ; Microglia/pathology ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Obesity/genetics ; Obesity/pathology ; Receptors, Interleukin-1 Type I/genetics ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
A Novel Mechanism of BAM8-22 Inhibiting Microglia Activation: Represses CX3CR1 Expression via Upregulating miR-184.
Autorzy :
Wang A; Department of Anesthesiology, Inner Mongolia Autonomous Region People's Hospital, Hohhot, 010017, China.
Tie M; Department of Anesthesiology, Inner Mongolia Autonomous Region People's Hospital, Hohhot, 010017, China.
Guo D; Department of Anesthesiology, Inner Mongolia Medical University, Hohhot, 010110, China.
Wu N; Department of Anesthesiology, Inner Mongolia Medical University, Hohhot, 010110, China.
Yao S; Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Yan L; Department of Intensive Care Unit, Inner Mongolia Autonomous Region People's Hospital, Hohhot, 010017, China.
Zhao X; Department of Cardiovascular Medicine, Inner Mongolia Autonomous Region People's Hospital, 20 Zhao Wuda Road, Saihan District, Hohhot, 010017, Inner Mongolia, People's Republic of China. .
Pokaż więcej
Źródło :
Journal of molecular neuroscience : MN [J Mol Neurosci] 2020 Apr; Vol. 70 (4), pp. 550-558. Date of Electronic Publication: 2019 Dec 12.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
CX3C Chemokine Receptor 1/*genetics
MicroRNAs/*metabolism
Microglia/*drug effects
Peptide Fragments/*pharmacology
Animals ; CX3C Chemokine Receptor 1/metabolism ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; Cell Line ; Cell Line, Tumor ; Cells, Cultured ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Lipopolysaccharides/toxicity ; Male ; Mice ; MicroRNAs/genetics ; Microfilament Proteins/genetics ; Microfilament Proteins/metabolism ; Microglia/metabolism ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Modulation of Monocyte-Driven Myositis in Alphavirus Infection Reveals a Role for CX 3 CR1 Macrophages in Tissue Repair.
Autorzy :
Zaid A; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia .; School of Medical Science, Griffith University, Southport, Queensland, Australia.; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Tharmarajah K; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia.; School of Medical Science, Griffith University, Southport, Queensland, Australia.; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Mostafavi H; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia.; School of Medical Science, Griffith University, Southport, Queensland, Australia.; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Freitas JR; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia.; School of Medical Science, Griffith University, Southport, Queensland, Australia.; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Sheng KC; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Foo SS; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Chen W; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Vider J; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia.; School of Medical Science, Griffith University, Southport, Queensland, Australia.
Liu X; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia.; School of Medical Science, Griffith University, Southport, Queensland, Australia.; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
West NP; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia.; School of Medical Science, Griffith University, Southport, Queensland, Australia.
Herrero LJ; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Taylor A; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia.; School of Medical Science, Griffith University, Southport, Queensland, Australia.; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Mackay LK; The Doherty Institute for Infection & Immunity, Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia.; The Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Melbourne, Parkville, Victoria, Australia.
Getts DR; The Discipline of Pathology, School of Medical Sciences, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.; Bosch Institute, School of Medical Sciences, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.; Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Myeloid Therapeutics Inc., Cambridge, Massachusetts, USA.
King NJC; The Discipline of Pathology, School of Medical Sciences, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.; Marie Bashir Institute for Infectious Diseases and Biosecurity, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia.; Australian Institute for Nanoscale Science and Technology, The University of Sydney, Sydney, New South Wales, Australia.
Mahalingam S; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia .; School of Medical Science, Griffith University, Southport, Queensland, Australia.; Institute for Glycomics, Griffith University, Southport, Queensland, Australia.
Pokaż więcej
Źródło :
MBio [mBio] 2020 Mar 03; Vol. 11 (2). Date of Electronic Publication: 2020 Mar 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Wound Healing*
Alphavirus Infections/*metabolism
Alphavirus Infections/*virology
CX3C Chemokine Receptor 1/*genetics
Monocytes/*metabolism
Myositis/*etiology
Myositis/*metabolism
Alphavirus Infections/pathology ; Animals ; Biomarkers ; Biopsy ; CX3C Chemokine Receptor 1/metabolism ; Disease Models, Animal ; Gene Expression Profiling ; Immunomodulation/genetics ; Immunophenotyping ; Macrophages/immunology ; Macrophages/metabolism ; Macrophages/virology ; Mice ; Mice, Transgenic ; Monocytes/immunology ; Monocytes/virology ; Myositis/pathology
Czasopismo naukowe
Tytuł :
Glial remodeling enhances short-term memory performance in Wistar rats.
Autorzy :
De Luca SN; School of Health and Biomedical Sciences RMIT University, Melbourne, VIC, 3083, Australia.
Soch A; School of Health and Biomedical Sciences RMIT University, Melbourne, VIC, 3083, Australia.
Sominsky L; School of Health and Biomedical Sciences RMIT University, Melbourne, VIC, 3083, Australia.
Nguyen TX; School of Health and Biomedical Sciences RMIT University, Melbourne, VIC, 3083, Australia.
Bosakhar A; School of Health and Biomedical Sciences RMIT University, Melbourne, VIC, 3083, Australia.
Spencer SJ; School of Health and Biomedical Sciences RMIT University, Melbourne, VIC, 3083, Australia. .; ARC Centre of Excellence for Nanoscale Biophotonics, RMIT University, Melbourne, VIC, Australia. .
Pokaż więcej
Źródło :
Journal of neuroinflammation [J Neuroinflammation] 2020 Feb 07; Vol. 17 (1), pp. 52. Date of Electronic Publication: 2020 Feb 07.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*metabolism
CX3C Chemokine Receptor 1/*metabolism
Memory, Short-Term/*physiology
Microglia/*metabolism
Monocytes/*metabolism
Spatial Memory/*physiology
Animals ; CX3C Chemokine Receptor 1/genetics ; Male ; Promoter Regions, Genetic ; Rats ; Rats, Transgenic ; Rats, Wistar
Czasopismo naukowe
Tytuł :
CX3CR1 contributes to streptozotocin-induced mechanical allodynia in the mouse spinal cord.
Autorzy :
Ni CM; Department of Endocrinology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Ling BY; Department of Emergency, Northern Jiangsu People's Hospital, Yangzhou University, Yangzhou 225001, China.
Xu X; Department of Endocrinology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Sun HP; Department of Endocrinology, the Affiliated Kunshan First People's Hospital of Jiangsu University, Kunshan 215300, China.
Jin H; Department of Endocrinology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Zhang YQ; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China.
Cao H; Department of Translational Neuroscience, Jing'an District Centre Hospital of Shanghai, Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China.
Xu L; Department of Endocrinology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi 214023, China.
Pokaż więcej
Źródło :
Journal of Zhejiang University. Science. B [J Zhejiang Univ Sci B] 2020 Feb.; Vol. 21 (2), pp. 166-171. Date of Electronic Publication: 2020 Feb 14.
Typ publikacji :
Journal Article
MeSH Terms :
CX3C Chemokine Receptor 1/*physiology
Diabetes Mellitus, Type 1/*complications
Diabetic Neuropathies/*etiology
Hyperalgesia/*etiology
Spinal Cord/*physiology
Streptozocin/*pharmacology
Animals ; CX3C Chemokine Receptor 1/antagonists & inhibitors ; Chemokine CX3CL1/physiology ; Diabetes Mellitus, Experimental/complications ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Region-specific transcriptomic and functional signatures of mononuclear phagocytes in the epididymis.
Autorzy :
Battistone MA; Program in Membrane Biology, Center for Systems Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Mendelsohn AC; Program in Membrane Biology, Center for Systems Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Spallanzani RG; Division of Immunology, Department of Microbiology an Immunobiology, Harvard Medical School, Evergrande Center for Immunologic Diseases, and Brigham and Women's Hospital, Boston, MA, USA.
Brown D; Program in Membrane Biology, Center for Systems Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Nair AV; Program in Membrane Biology, Center for Systems Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Breton S; Program in Membrane Biology, Center for Systems Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Pokaż więcej
Źródło :
Molecular human reproduction [Mol Hum Reprod] 2020 Jan 01; Vol. 26 (1), pp. 14-29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CX3C Chemokine Receptor 1/*immunology
Epididymis/*immunology
Fertility/*genetics
Phagocytes/*immunology
Spermatozoa/*immunology
Transcriptome/*immunology
Animals ; Antigen Presentation ; Antigens, CD/genetics ; Antigens, CD/immunology ; Autoantigens/genetics ; Autoantigens/immunology ; CX3C Chemokine Receptor 1/deficiency ; CX3C Chemokine Receptor 1/genetics ; Cell Communication ; Chemokines, CC/genetics ; Chemokines, CC/immunology ; Dendritic Cells/cytology ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Epididymis/cytology ; Epididymis/metabolism ; Epithelial Cells/cytology ; Epithelial Cells/immunology ; Epithelial Cells/metabolism ; Gene Expression Profiling ; Gene Expression Regulation ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/immunology ; Male ; Mice ; Mice, Knockout ; Phagocytes/cytology ; Phagocytes/metabolism ; Protein Transport ; Receptors, Interleukin/genetics ; Receptors, Interleukin/immunology ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Receptors, Tumor Necrosis Factor, Type I/immunology ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/immunology ; Spermatozoa/cytology ; Spermatozoa/metabolism
Czasopismo naukowe
Tytuł :
Cx3cr1- deficient microglia exhibit a premature aging transcriptome.
Autorzy :
Gyoneva S; Acute Neurology, Biogen, Cambridge, MA, USA .
Hosur R; Computational Biology and Genomics, Biogen, Cambridge, MA, USA.
Gosselin D; Cell and Molecular Medicine, University of California San Diego, San Diego, CA, USA.
Zhang B; Computational Biology and Genomics, Biogen, Cambridge, MA, USA.
Ouyang Z; Cell and Molecular Medicine, University of California San Diego, San Diego, CA, USA.
Cotleur AC; Acute Neurology, Biogen, Cambridge, MA, USA.
Peterson M; Translational Neuropathology, Biogen, Cambridge, MA, USA.
Allaire N; Computational Biology and Genomics, Biogen, Cambridge, MA, USA.
Challa R; Computational Biology and Genomics, Biogen, Cambridge, MA, USA.
Cullen P; Computational Biology and Genomics, Biogen, Cambridge, MA, USA.
Roberts C; Computational Biology and Genomics, Biogen, Cambridge, MA, USA.
Miao K; Acute Neurology, Biogen, Cambridge, MA, USA.
Reynolds TL; Translational Neuropathology, Biogen, Cambridge, MA, USA.
Glass CK; Cell and Molecular Medicine, University of California San Diego, San Diego, CA, USA.; School of Medicine, University of California San Diego, San Diego, CA, USA.
Burkly L; Acute Neurology, Biogen, Cambridge, MA, USA.
Ransohoff RM; Acute Neurology, Biogen, Cambridge, MA, USA .
Pokaż więcej
Źródło :
Life science alliance [Life Sci Alliance] 2019 Dec 02; Vol. 2 (6). Date of Electronic Publication: 2019 Dec 02 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aging, Premature/*genetics
CX3C Chemokine Receptor 1/*deficiency
Microglia/*metabolism
Animals ; CX3C Chemokine Receptor 1/genetics ; CX3C Chemokine Receptor 1/metabolism ; Disease Models, Animal ; Female ; Gene Deletion ; Genetic Profile ; Inflammation/genetics ; Inflammation/metabolism ; Lipopolysaccharides/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Neurons/metabolism ; Receptors, Chemokine/deficiency ; Signal Transduction ; Transcriptome
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies