Temat: "CYCLOOXYGENASE 2" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Design, Synthesis, and Biological Evaluation of Novel Phenoxy Acetic Acid Derivatives as Selective COX-2 Inhibitors Coupled with Comprehensive Bio-Pharmacological Inquiry, Histopathological Profiling, and Toxicological Scrutiny.
Autorzy:: Alshaye NA; Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Elgohary MK; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City 11829, Cairo, Egypt.
Elkotamy MS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian-Russian University, Badr City 11829, Cairo, Egypt.
Abdel-Aziz HA; Applied Organic Chemistry Department, National Research Center, Dokki 12622, Cairo, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Mar 15; Vol. 29 (6). Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*
Anti-Inflammatory Agents*/therapeutic use
Humans ; Cyclooxygenase 2/metabolism ; Acetic Acid ; Molecular Docking Simulation ; Inflammation/drug therapy ; Edema/drug therapy ; Structure-Activity Relationship ; Drug Design ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology

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Skocz do pozycji: 2.

Tytuł:: In silico screening, synthesis, characterization and biological evaluation of novel anticancer agents as potential COX-2 inhibitors.
Autorzy:: Sahu A; Tumor Biology, ICMR-National Institute of Pathology, New Delhi, 110029, India.
Pradhan D; Indian Biological Data Center, Regional Centre for Biotechnology, Faridabad, 121001, India.
Veer B; Department of Applied Chemistry, Delhi Technological University, New Delhi, 110042, India.
Kumar S; Tumor Biology, ICMR-National Institute of Pathology, New Delhi, 110029, India.
Singh R; Department of Applied Chemistry, Delhi Technological University, New Delhi, 110042, India.
Raza K; Department of Computer Science, Jamia Millia Islamia, New Delhi, 110025, India.
Rizvi MA; Department of Bioscience, Jamia Millia Islamia, New Delhi, 110025, India.
Jain AK; Biomedical Informatics Centre, ICMR-National Institute of Pathology, New Delhi, 110029, India.
Verma S; Tumor Biology, ICMR-National Institute of Pathology, New Delhi, 110029, India. .; Pokaż więcej
Źródło:: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences [Daru] 2023 Dec; Vol. 31 (2), pp. 119-133. Date of Electronic Publication: 2023 Jul 15.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Cyclooxygenase 2 Inhibitors*/chemistry
Antineoplastic Agents*/chemistry
Humans ; Structure-Activity Relationship ; Cell Line, Tumor ; Cyclooxygenase 2/metabolism ; Dinoprostone/pharmacology ; Drug Screening Assays, Antitumor ; Drug Design ; Molecular Docking Simulation ; Molecular Structure ; Cell Proliferation

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Skocz do pozycji: 3.

Tytuł:: Development of Novel Pyrrole Derivatives and Their Cinnamic Hybrids as Dual COX-2/LOX Inhibitors.
Autorzy:: Noti V; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Pontiki E; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Hadjipavlou-Litina D; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 05; Vol. 28 (24). Date of Electronic Publication: 2023 Dec 05.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Lipoxygenase*/metabolism
Cyclooxygenase 2/metabolism ; Molecular Docking Simulation ; Lipoxygenase Inhibitors/pharmacology ; Structure-Activity Relationship

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Skocz do pozycji: 4.

Tytuł:: Towards safer anti-inflammatory therapy: synthesis of new thymol-pyrazole hybrids as dual COX-2/5-LOX inhibitors.
Autorzy:: El-Miligy MMM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Al-Kubeisi AK; Pharmacy Department, Alnukhba University College, Baghdad, Iraq.
Bekhit MG; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt.
El-Zemity SR; Department of Chemistry and Technology of Pesticides, Faculty of Agriculture, Alexandria University, Alexandria, Egypt.
Nassra RA; Medical Biochemistry Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Hazzaa AA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 294-308.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Thymol*
Rats ; Animals ; Cyclooxygenase 2 ; Lipoxygenase Inhibitors/pharmacology ; Celecoxib/pharmacology ; Quercetin ; Molecular Docking Simulation ; Anti-Inflammatory Agents/pharmacology ; Pyrazoles/pharmacology

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Skocz do pozycji: 5.

Tytuł:: Novel N -methylsulfonyl-indole derivatives: biological activity and COX-2/5-LOX inhibitory effect with improved gastro protective profile and reduced cardio vascular risks.
Autorzy:: Philoppes JN; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Abourehab MAS; Department of Pharmaceutics, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Sebak M; Microbiology and Immunology Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
A Darwish M; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Nahda University, Beni-Suef, Egypt.
Lamie PF; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 246-266.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Indoles*/pharmacology
Protective Agents*/pharmacology
Cyclooxygenase 2 ; Stomach ; Animals ; Anti-Bacterial Agents/pharmacology

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Skocz do pozycji: 6.

Tytuł:: Discovering the Active Ingredients of Medicine and Food Homologous Substances for Inhibiting the Cyclooxygenase-2 Metabolic Pathway by Machine Learning Algorithms.
Autorzy:: Tian Y; State Key Laboratory of Chemical Resource Engineering, Department of Pharmaceutical Engineering, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Beijing 100029, China.
Zhang Z; State Key Laboratory of Chemical Resource Engineering, Department of Pharmaceutical Engineering, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Beijing 100029, China.; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Yan A; State Key Laboratory of Chemical Resource Engineering, Department of Pharmaceutical Engineering, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Beijing 100029, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Sep 23; Vol. 28 (19). Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Anti-Inflammatory Agents*
Cyclooxygenase 2 ; Molecular Docking Simulation ; Algorithms ; Machine Learning ; Metabolic Networks and Pathways

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Skocz do pozycji: 7.

Tytuł:: Design, Synthesis, and Evaluation of the COX-2 Inhibitory Activities of New 1,3-Dihydro- 2H -indolin-2-one Derivatives.
Autorzy:: Pan T; College of Pharmacy, Guizhou University, Guiyang 550025, China.
He M; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province, Chinese Academy of Sciences, Guiyang 550014, China.
Deng L; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province, Chinese Academy of Sciences, Guiyang 550014, China.
Li J; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province, Chinese Academy of Sciences, Guiyang 550014, China.
Fan Y; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province, Chinese Academy of Sciences, Guiyang 550014, China.
Hao X; Kunming Institute of Botany, Chinese Academy of Sciences (CAS), Kunming 650201, China.
Mu S; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China.; The Key Laboratory of Chemistry for Natural Products of Guizhou Province, Chinese Academy of Sciences, Guiyang 550014, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jun 09; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 09.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Antineoplastic Agents*/pharmacology
Cyclooxygenase 2/metabolism ; Molecular Structure ; Structure-Activity Relationship ; Molecular Docking Simulation ; Anti-Inflammatory Agents/pharmacology

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Skocz do pozycji: 8.

Tytuł:: Discovery of andrographolide hit analog as a potent cyclooxygenase-2 inhibitor through consensus MD-simulation, electrostatic potential energy simulation and ligand efficiency metrics.
Autorzy:: Jain P; School of Biosciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India.
Satija J; Centre for Nanobiotechnology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India.
Sudandiradoss C; School of Biosciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 May 19; Vol. 13 (1), pp. 8147. Date of Electronic Publication: 2023 May 19.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Molecular Dynamics Simulation*
Humans ; Cyclooxygenase 2 ; Ligands ; Molecular Docking Simulation ; Static Electricity

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Skocz do pozycji: 9.

Tytuł:: Modeling adult COX-2 cerebrospinal fluid pharmacokinetics to inform pediatric investigation.
Autorzy:: Hannam JA; Department Pharmacology & Clinical Pharmacology, Faculty Medicine and Health Sciences, University of Auckland, Auckland, New Zealand.
Murto KT; Department Anesthesiology and Pain Medicine, University of Ottawa, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Anderson BJ; Department Anaesthesiology, Faculty Medicine and Health Sciences, University of Auckland, Auckland, New Zealand.
Dembo G; Department of Anesthesiology, University of Washington, Seattle, Washington, USA.
Kharasch ED; Department of Anesthesiology and Clinical Chemistry, Duke University School of Medicine, Durham, North Carolina, USA.; Pokaż więcej
Źródło:: Paediatric anaesthesia [Paediatr Anaesth] 2023 Apr; Vol. 33 (4), pp. 291-302. Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*
Transfer Factor*
Humans ; Child ; Adult ; Celecoxib ; Cyclooxygenase 2 ; Anti-Inflammatory Agents, Non-Steroidal

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Skocz do pozycji: 10.

Tytuł:: New NSAID Conjugates as Potent and Selective COX-2 Inhibitors: Synthesis, Molecular Modeling and Biological Investigation.
Autorzy:: Bokhtia RM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Panda SS; Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, USA.
Girgis AS; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt.
Samir N; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.
Said MF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Abdelnaser A; Institute of Global Health and Human Ecology, School of Sciences and Engineering, The American University in Cairo (AUC), Cairo 11835, Egypt.
Nasr S; Institute of Global Health and Human Ecology, School of Sciences and Engineering, The American University in Cairo (AUC), Cairo 11835, Egypt.
Bekheit MS; Department of Pesticide Chemistry, National Research Centre, Dokki, Giza 12622, Egypt.
Dawood AS; Institute of Global Health and Human Ecology, School of Sciences and Engineering, The American University in Cairo (AUC), Cairo 11835, Egypt.
Sharma H; College of Pharmacy, Southwestern Oklahoma State University, Weatherford, OK 73096, USA.
Wade M; Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, USA.
Sharma SK; Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, USA.; Department of Computer Science and Engineering, University of California, Merced, CA 95343, USA.
Ghanim AM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.; Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, USA.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 17; Vol. 28 (4). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Ibuprofen*/therapeutic use
Rats ; Animals ; Structure-Activity Relationship ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Anti-Inflammatory Agents/pharmacology ; Indomethacin/pharmacology ; Carrageenan/adverse effects ; Cyclooxygenase 2/metabolism ; Edema/drug therapy ; Molecular Docking Simulation

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Skocz do pozycji: 11.

Tytuł:: Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme.
Autorzy:: El-Dershaby NH; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt.
El-Hawash SA; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Kassab SE; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt.; Department of organic and Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, Menoufia,Egypt.
Dabees HG; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt.
Abdel Moneim AE; Department of Zoology and Entomology, Faculty of Science, Helwan University, Cairo, Egypt.
Abdel Wahab IA; Microbiology and Immunology Department, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt.
Abd-Alhaseeb MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Damanhur University, Damanhour, Egypt.
El-Miligy MMM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1737-1751.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Dihydropteroate Synthase*/antagonists & inhibitors
Enzyme Inhibitors*/pharmacology
Sepsis*/drug therapy
Animals ; Anti-Bacterial Agents/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Celecoxib/adverse effects ; Cyclooxygenase 2 ; Dinoprostone ; Edema/drug therapy ; Mice ; Sulfasalazine/pharmacology ; Sulfonamides/pharmacology

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Skocz do pozycji: 12.

Tytuł:: Celecoxib impairs primary human myoblast proliferation and differentiation independent of cyclooxygenase 2 inhibition.
Autorzy:: Matheny RW Jr; Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.; Military Operational Medicine Research Program, Ft. Detrick, Maryland, USA.
Kolb AL; Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Geddis AV; Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.
Roberts BM; Military Performance Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts, USA.; Pokaż więcej
Źródło:: Physiological reports [Physiol Rep] 2022 Nov; Vol. 10 (21), pp. e15481.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Myoblasts, Skeletal*
Humans ; Celecoxib/pharmacology ; Cyclooxygenase 2 ; Cell Differentiation/physiology ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Cell Proliferation

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Skocz do pozycji: 13.

Tytuł:: Involvement of Cyclooxygenase-2 in Establishing an Immunosuppressive Microenvironment in Tumorspheres Derived from TMZ-Resistant Glioblastoma Cell Lines and Primary Cultures.
Autorzy:: Lombardi F; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Augello FR; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Artone S; PhD School in Medicine and Public Health, Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Ciafarone A; PhD School in Health & Environmental Sciences, Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Topi S; Department of Clinical Disciplines, Aleksandër Xhuvani University, 3001 Elbasan, Albania.
Cifone MG; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Cinque B; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Palumbo P; Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Jan 30; Vol. 13 (3). Date of Electronic Publication: 2024 Jan 30.
Typ publikacji:: Journal Article
MeSH Terms:: Brain Neoplasms*/metabolism
Cyclooxygenase 2*/metabolism
Glioblastoma*/metabolism
Humans ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; Temozolomide/pharmacology ; Tumor Microenvironment

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Skocz do pozycji: 14.

Tytuł:: Antiinflammation Derived Suzuki-Coupled Fenbufens as COX-2 Inhibitors: Minilibrary Construction and Bioassay.
Autorzy:: Farn SS; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 30013, Taiwan.; Isotope Application Division, Institute of Nuclear Energy Research, Taoyuan 32546, Taiwan.
Lai YB; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 30013, Taiwan.
Hua KF; Department of Biotechnology and Animal Science, National Ilan University, Ilan 26007, Taiwan.
Chen HP; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 30013, Taiwan.
Yu TY; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 30013, Taiwan.
Lo SN; Isotope Application Division, Institute of Nuclear Energy Research, Taoyuan 32546, Taiwan.
Shen LH; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 30013, Taiwan.
Sheu RJ; Institute of Nuclear Engineering and Science, National Tsinghua University, Hsinchu 30013, Taiwan.
Yu CS; Department of Biomedical Engineering and Environmental Sciences, National Tsinghua University, Hsinchu 30013, Taiwan.; Institute of Nuclear Engineering and Science, National Tsinghua University, Hsinchu 30013, Taiwan.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Apr 29; Vol. 27 (9). Date of Electronic Publication: 2022 Apr 29.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Drug Design*
Anti-Inflammatory Agents/pharmacology ; Biological Assay ; Cyclooxygenase 1 ; Cyclooxygenase 2/metabolism ; Molecular Docking Simulation ; Molecular Structure ; Phenylbutyrates ; Structure-Activity Relationship

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Skocz do pozycji: 15.

Tytuł:: Computational Analysis and Biological Activities of Oxyresveratrol Analogues, the Putative Cyclooxygenase-2 Inhibitors.
Autorzy:: Jongkon N; Department of Social and Applied Science, College of Industrial Technology, King Mongkut's University of Technology North Bangkok, Bangkok 10800, Thailand.
Seaho B; Department of Chemistry, Faculty of Science and Technology, Thammasat University, Pathum Thani 12120, Thailand.
Tayana N; Drug Discovery and Development Center, Office of Advance Science and Technology, Thammasat University, Pathum Thani 12120, Thailand.
Prateeptongkum S; Department of Chemistry, Faculty of Science and Technology, Thammasat University, Pathum Thani 12120, Thailand.
Duangdee N; Drug Discovery and Development Center, Office of Advance Science and Technology, Thammasat University, Pathum Thani 12120, Thailand.
Jaiyong P; Department of Chemistry, Faculty of Science and Technology, Thammasat University, Pathum Thani 12120, Thailand.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Apr 06; Vol. 27 (7). Date of Electronic Publication: 2022 Apr 06.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2 Inhibitors*/pharmacology
Stilbenes*/analysis
Stilbenes*/pharmacology
Cyclooxygenase 1 ; Cyclooxygenase 2/metabolism ; Humans ; Molecular Docking Simulation ; Plant Extracts/chemistry

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Skocz do pozycji: 16.

Tytuł:: Endometrial receptivity defects MUC-1 and COX-2 polymorphisms in endometriosis.
Autorzy:: Budihastuti UR; Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Jawa Tengah, Indonesia.; Dr. Moewardi General Hospital, Jawa Tengah, Indonesia.
Dasuki D; Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Sadewa AH; Department of Biochemistry, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Utoro T; Department of Anatomic Pathology, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.; Pokaż więcej
Źródło:: Journal of medicine and life [J Med Life] 2023 Oct; Vol. 16 (10), pp. 1503-1507.
Typ publikacji:: Journal Article
MeSH Terms:: Cyclooxygenase 2*/genetics
Endometriosis*/genetics
Mucin-1*/genetics
Female ; Humans ; Endometrium ; Polymorphism, Genetic

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Skocz do pozycji: 17.

Tytuł:: Selective COX-2 inhibitors do not increase gastrointestinal reactions after colorectal cancer surgery: a systematic review and meta-analysis.
Autorzy:: Hu T; Department of General Practice, Anqing Municipal Hospital, Anqing, 246000, AnHui, China.
Liu CJ; Department of General Medicine, Affiliated Anqing First People's Hospital of Anhui Medical University, Anqing, 246000, AnHui, China.
Yin X; Department of General Practice, Anqing Municipal Hospital, Anqing, 246000, AnHui, China. .
Tang W; Department of General Practice, Anqing Municipal Hospital, Anqing, 246000, AnHui, China.
Yin L; Department of General Practice, Anqing Municipal Hospital, Anqing, 246000, AnHui, China.
Bai H; Department of General Practice, Anqing Municipal Hospital, Anqing, 246000, AnHui, China.
Liu F; Department of General Practice, Anqing Municipal Hospital, Anqing, 246000, AnHui, China.
Wang D; Department of General Practice, Anqing Municipal Hospital, Anqing, 246000, AnHui, China.
Li Y; Department of General Practice, Anqing Municipal Hospital, Anqing, 246000, AnHui, China.; Pokaż więcej
Źródło:: BMC gastroenterology [BMC Gastroenterol] 2023 Aug 14; Vol. 23 (1), pp. 281. Date of Electronic Publication: 2023 Aug 14.
Typ publikacji:: Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:: Colorectal Neoplasms*/surgery
Colorectal Neoplasms*/drug therapy
Cyclooxygenase 2 Inhibitors*/adverse effects
Humans ; Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Celecoxib/adverse effects ; Neoplasm Recurrence, Local ; Randomized Controlled Trials as Topic ; Sulfones/adverse effects

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Skocz do pozycji: 18.

Tytuł:: Design, Synthesis, Anti-Inflammatory Activity, DFT Modeling and Docking Study of New Ibuprofen Derivatives.
Autorzy:: Abbas AM; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Nasrallah HH; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.; Chemistry Department, Faculty of Dentistry, Sinai University, Kantara 41612, Egypt.
Aboelmagd A; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.
Kishk SM; Medicinal Chemistry Department, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt.
Boyd WC; Chemistry Department, College of Arts and Sciences, Cleveland State University, Cleveland, OH 44115, USA.
Kalil H; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.; Chemistry Department, College of Arts and Sciences, Cleveland State University, Cleveland, OH 44115, USA.
Orabi AS; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 21; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:: Journal Article
MeSH Terms:: Ibuprofen*/pharmacology
Ibuprofen*/chemistry
Anti-Inflammatory Agents*/pharmacology
Molecular Docking Simulation ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2 Inhibitors/pharmacology

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Skocz do pozycji: 19.

Tytuł:: Repurposed Drugs Celecoxib and Fmoc-L-Leucine Alone and in Combination as Temozolomide-Resistant Antiglioma Agents-Comparative Studies on Normal and Immortalized Cell Lines, and on C. elegans .
Autorzy:: Uram Ł; Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańcow Warszawy Ave., 35-959 Rzeszów, Poland.
Pieńkowska N; Department of Experimental and Clinical Pharmacology, University of Rzeszów, Kopisto 2a, 35-959 Rzeszów, Poland.
Misiorek M; Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańcow Warszawy Ave., 35-959 Rzeszów, Poland.
Szymaszek Ż; Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańcow Warszawy Ave., 35-959 Rzeszów, Poland.
Twardowska M; Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańcow Warszawy Ave., 35-959 Rzeszów, Poland.
Siorek M; Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańcow Warszawy Ave., 35-959 Rzeszów, Poland.
Wołowiec S; Medical College, University of Rzeszów, 1a Warzywna Street, 35-310 Rzeszów, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 12; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:: Journal Article
MeSH Terms:: Caenorhabditis elegans*/metabolism
Glioblastoma*/drug therapy
Leucine/*analogs & derivatives
Animals ; Humans ; Celecoxib/pharmacology ; Celecoxib/therapeutic use ; Temozolomide/pharmacology ; Temozolomide/therapeutic use ; Cyclooxygenase 2/metabolism ; PPAR gamma/metabolism ; Sulfonamides/pharmacology ; Pyrazoles/pharmacology ; Apoptosis ; Cyclooxygenase 2 Inhibitors/pharmacology ; Cyclooxygenase 2 Inhibitors/therapeutic use ; Cell Line ; Cell Line, Tumor

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Tytuł:: Comparing anti-tumor and anti-self immunity in a patient with melanoma receiving immune checkpoint blockade.
Autorzy:: Chen S; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
McMiller TL; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Soni A; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Contra Costa Pathology Associates, Pleasant Hill, CA, USA.
Succaria F; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Sidhom JW; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Mount Sinai School of Medicine, New York, NY, USA.
Cappelli LC; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Casciola-Rosen LA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Morales IR; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Sankaran P; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Crossbow Therapeutics, Cambridge, MA, USA.
Berger AE; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Deutsch JS; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Zhu QC; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Anders RA; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Hooper JE; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Stanford University School of Medicine, Palo Alto, CA, USA.
Pardoll DM; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Lipson EJ; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Taube JM; Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Topalian SL; Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. .; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2024 Mar 05; Vol. 22 (1), pp. 241. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:: Journal Article
MeSH Terms:: Melanoma*/drug therapy
Melanoma*/genetics
Blood Group Antigens*
Humans ; Immune Checkpoint Inhibitors ; Cyclooxygenase 2 ; Dinoprostone ; Cyclooxygenase 2 Inhibitors ; Inflammation ; Receptors, Antigen, T-Cell

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