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Tytuł :
CYP1A1 and GSTs common gene variations and presbycusis risk: a genetic association analysis and a bioinformatics approach.
Autorzy :
Karimian M; Department of Molecular and Cell Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, 47416-95447, Iran. .
Behjati M; Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
Barati E; Department of Anatomy, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Ehteram T; Department of ENT, School of Medicine, Kashan University of Medical Science, Qotb-e Ravandi Blvd, Kashan, 8715988141, Iran.
Karimian A; Department of Anatomy, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Dec; Vol. 27 (34), pp. 42600-42610. Date of Electronic Publication: 2020 Jul 25.
Typ publikacji :
Journal Article
MeSH Terms :
Cytochrome P-450 CYP1A1*/genetics
Presbycusis*/genetics
Case-Control Studies ; Computational Biology ; Genetic Predisposition to Disease ; Genotype ; Glutathione Transferase/genetics ; Humans ; Iran ; Risk Factors
Czasopismo naukowe
Tytuł :
Expression and localization of the aryl hydrocarbon receptors and cytochrome P450 1A during early development of Atlantic cod (Gadus morhua).
Autorzy :
Aranguren-Abadía L; Department of Biological Sciences, University of Bergen, Bergen, Norway.
Donald CE; Institute of Marine Research, Bergen, Norway.
Eilertsen M; Department of Biological Sciences, University of Bergen, Bergen, Norway.
Gharbi N; NORCE Norwegian Research Centre AS, Uni Research Environment, Bergen, Norway.
Tronci V; NORCE Norwegian Research Centre AS, Uni Research Environment, Bergen, Norway.
Sørhus E; Institute of Marine Research, Bergen, Norway.
Mayer P; Department of Environmental Engineering, Technical University of Denmark, Lyngby, Denmark.
Nilsen TO; Department of Biological Sciences, University of Bergen, Bergen, Norway.
Meier S; Institute of Marine Research, Bergen, Norway.
Goksøyr A; Department of Biological Sciences, University of Bergen, Bergen, Norway; Institute of Marine Research, Bergen, Norway.
Karlsen OA; Department of Biological Sciences, University of Bergen, Bergen, Norway. Electronic address: .
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Źródło :
Aquatic toxicology (Amsterdam, Netherlands) [Aquat Toxicol] 2020 Sep; Vol. 226, pp. 105558. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article
MeSH Terms :
Cytochrome P-450 CYP1A1/*metabolism
Gadus morhua/*growth & development
Gene Expression Regulation, Developmental/*drug effects
Receptors, Aryl Hydrocarbon/*metabolism
Animals ; Benzo(a)pyrene/toxicity ; Cytochrome P-450 CYP1A1/genetics ; Embryo, Nonmammalian/drug effects ; Embryo, Nonmammalian/metabolism ; Eye/drug effects ; Eye/embryology ; Eye/metabolism ; Gadus morhua/genetics ; Gadus morhua/metabolism ; Larva/drug effects ; Larva/genetics ; Liver/drug effects ; Liver/growth & development ; Liver/metabolism ; Receptors, Aryl Hydrocarbon/genetics ; Water Pollutants, Chemical/toxicity
Czasopismo naukowe
Tytuł :
Cytochrome P450 1 enzymes in black rockfish, Sebastes schlegelii: Molecular characterization and expression patterns after exposure to benzo[a]pyrene.
Autorzy :
Woo SJ; Department of Aquatic Life Medicine, Pukyong National University, Busan 48513, South Korea; Pathology Division, National Instititue of Fisheries Science, Busan 46083, South Korea.
Chung JK; Department of Aquatic Life Medicine, Pukyong National University, Busan 48513, South Korea. Electronic address: .
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Źródło :
Aquatic toxicology (Amsterdam, Netherlands) [Aquat Toxicol] 2020 Sep; Vol. 226, pp. 105566. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article
MeSH Terms :
Benzo(a)pyrene/*toxicity
Cytochrome P-450 CYP1A1/*metabolism
Gene Expression/*drug effects
Perciformes/*metabolism
Water Pollutants, Chemical/*toxicity
Animals ; Cytochrome P-450 CYP1A1/genetics ; Gills/drug effects ; Gills/metabolism ; Liver/drug effects ; Liver/metabolism ; Perciformes/genetics ; Perciformes/growth & development ; Receptors, Aryl Hydrocarbon/metabolism ; Republic of Korea
Czasopismo naukowe
Tytuł :
Zebrafish CYP1A expression in transgenic Caenorhabditis elegans protects from exposures to benzo[a]pyrene and a complex polycyclic aromatic hydrocarbon mixture.
Autorzy :
Harris JB; Nicholas School of the Environment, Box 90328, Duke University, Durham, NC, 27708, USA.
Hartman JH; Nicholas School of the Environment, Box 90328, Duke University, Durham, NC, 27708, USA.
Luz AL; Nicholas School of the Environment, Box 90328, Duke University, Durham, NC, 27708, USA.
Wilson JY; Department of Biology, McMaster University, Hamilton, ON, L8S 4K1, Canada.
Dinyari A; Nicholas School of the Environment, Box 90328, Duke University, Durham, NC, 27708, USA.
Meyer JN; Nicholas School of the Environment, Box 90328, Duke University, Durham, NC, 27708, USA. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2020 Jul; Vol. 440, pp. 152473. Date of Electronic Publication: 2020 May 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzo(a)pyrene/*antagonists & inhibitors
Benzo(a)pyrene/*toxicity
Caenorhabditis elegans/*metabolism
Cytochrome P-450 CYP1A1/*genetics
Polycyclic Aromatic Hydrocarbons/*antagonists & inhibitors
Polycyclic Aromatic Hydrocarbons/*toxicity
Water Pollutants, Chemical/*toxicity
Zebrafish/*metabolism
Adenosine Triphosphate/metabolism ; Animals ; Animals, Genetically Modified ; Cytochrome P-450 CYP1A1/metabolism ; DNA Repair/drug effects ; Embryo, Nonmammalian ; Larva/drug effects ; Larva/growth & development ; Molecular Weight ; Reproduction/drug effects
Czasopismo naukowe
Tytuł :
Prediction of regioselectivity and preferred order of CYP1A1-mediated metabolism: Solving the interaction of human and rat CYP1A1 forms with ligands on the template system.
Autorzy :
Yamazoe Y; Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aramaki-Aoba, Aoba-ku, Sendai 980-8578, Japan; Food Safety Commission, Cabinet Office, Government of Japan, Akasaka Park Bld., Tokyo, 107-6122, Japan; Division of Risk Assessment, National Institute of Health Sciences, Tonomachi 3-25-26, Kawasaki, Kanagawa, 210-9501, Japan. Electronic address: .
Yoshinari K; Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aramaki-Aoba, Aoba-ku, Sendai 980-8578, Japan; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526 Japan.
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Źródło :
Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2020 Feb; Vol. 35 (1), pp. 165-185. Date of Electronic Publication: 2019 Nov 02.
Typ publikacji :
Journal Article
MeSH Terms :
Cytochrome P-450 CYP1A1/*metabolism
Cytochrome P-450 Enzyme Inhibitors/*metabolism
Animals ; Cytochrome P-450 CYP1A1/antagonists & inhibitors ; Cytochrome P-450 CYP1A1/chemistry ; Cytochrome P-450 Enzyme Inhibitors/chemistry ; Cytochrome P-450 Enzyme Inhibitors/pharmacology ; Humans ; Ligands ; Molecular Structure ; Rats
Czasopismo naukowe
Tytuł :
Cytochrome P450 1A1 enhances Arginase-1 expression, which reduces LPS-induced mouse peritonitis by targeting JAK1/STAT6.
Autorzy :
Tian LX; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Daping Hospital, Army Medical University, Chongqing, China.
Tang X; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Daping Hospital, Army Medical University, Chongqing, China.
Zhu JY; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Daping Hospital, Army Medical University, Chongqing, China.
Zhang W; Emergency and Trauma College of Hainan Medical University, Xueyuan Road 3, Haikou, China.
Tang WQ; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Daping Hospital, Army Medical University, Chongqing, China.
Yan J; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Daping Hospital, Army Medical University, Chongqing, China.
Xu X; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Daping Hospital, Army Medical University, Chongqing, China.
Liang HP; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Daping Hospital, Army Medical University, Chongqing, China. Electronic address: .
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Źródło :
Cellular immunology [Cell Immunol] 2020 Mar; Vol. 349, pp. 104047. Date of Electronic Publication: 2020 Jan 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Arginase/*biosynthesis
Cytochrome P-450 CYP1A1/*physiology
Janus Kinase 1/*antagonists & inhibitors
Macrophages, Peritoneal/*drug effects
Peritonitis/*prevention & control
STAT6 Transcription Factor/*antagonists & inhibitors
Signal Transduction/*drug effects
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid/pharmacology ; Adoptive Transfer ; Animals ; Arachidonate 15-Lipoxygenase/physiology ; Arginase/genetics ; Cytochrome P-450 CYP1A1/biosynthesis ; Cytochrome P-450 CYP1A1/genetics ; Endotoxins/toxicity ; Humans ; Hydroxyeicosatetraenoic Acids/biosynthesis ; Hydroxyeicosatetraenoic Acids/genetics ; Hydroxyeicosatetraenoic Acids/pharmacology ; Interleukin-4/pharmacology ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/metabolism ; Leukocytes, Mononuclear/transplantation ; Macrophages, Peritoneal/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Peritonitis/chemically induced ; RAW 264.7 Cells ; RNA Interference ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; Receptors, Cytoplasmic and Nuclear/biosynthesis ; Receptors, Cytoplasmic and Nuclear/genetics ; THP-1 Cells ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Serotonin Modulates AhR Activation by Interfering with CYP1A1-Mediated Clearance of AhR Ligands.
Autorzy :
Manzella CR; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL, USA.
Ackerman M; Division of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.
Singhal M; Division of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.
Ticho AL; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL, USA.
Ceh J; Division of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.
Alrefai WA; Division of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.; Jesse Brown VA Medical Center, Chicago, IL, USA.
Saksena S; Division of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.; Jesse Brown VA Medical Center, Chicago, IL, USA.
Dudeja PK; Division of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA.; Jesse Brown VA Medical Center, Chicago, IL, USA.
Gill RK; Division of Gastroenterology & Hepatology, University of Illinois at Chicago, Chicago, IL, USA, .
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Źródło :
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology [Cell Physiol Biochem] 2020 Feb 05; Vol. 54 (1), pp. 126-141.
Typ publikacji :
Journal Article
MeSH Terms :
Cytochrome P-450 CYP1A1/*metabolism
Receptors, Aryl Hydrocarbon/*metabolism
Serotonin/*pharmacology
Transcription, Genetic/*drug effects
Animals ; Caco-2 Cells ; Carbazoles/pharmacology ; Cytochrome P-450 CYP1A1/genetics ; Cytochrome P-450 CYP1B1/genetics ; Cytochrome P-450 CYP1B1/metabolism ; Humans ; Ligands ; Male ; Mice ; Mice, Knockout ; RNA, Messenger/metabolism ; Receptors, Aryl Hydrocarbon/chemistry ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/genetics ; Serotonin Plasma Membrane Transport Proteins/deficiency ; Serotonin Plasma Membrane Transport Proteins/genetics ; Signal Transduction/drug effects ; Substrate Specificity ; beta-Naphthoflavone/administration & dosage
Czasopismo naukowe
Tytuł :
Correlation between CYP1A1 polymorphisms and susceptibility to glyphosate-induced reduction of serum cholinesterase: A case-control study of a Chinese population.
Autorzy :
Cai W; Suzhou Municipal Hospital, Suzhou Affiliated Hosptial of Nanjing Medical University, Suzhou, Jiangsu 215001, China; Institute of Occupational Disease Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China.
Zhang F; Institute of Occupational Disease Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China.
Zhong L; Institute of Occupational Disease Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China.
Chen D; Department of Toxicology and Function Assessment, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China.
Guo H; Institute of Occupational Disease Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China; Institute of Occupational Disease Prevention, Jiangyin Municipal Center for Disease Control and Prevention, Jiangyin, Jiangsu 214434, China.
Zhang H; Institute of Occupational Disease Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China.
Zhu B; Institute of Occupational Disease Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China. Electronic address: .
Liu X; Institute of Occupational Disease Prevention, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China. Electronic address: .
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Źródło :
Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2020 Jan; Vol. 162, pp. 23-28. Date of Electronic Publication: 2019 Aug 29.
Typ publikacji :
Journal Article
MeSH Terms :
Cytochrome P-450 CYP1A1*
Polymorphism, Genetic*
Adult ; Case-Control Studies ; Cholinesterases ; Female ; Genotype ; Glycine/analogs & derivatives ; Humans
Czasopismo naukowe
Tytuł :
Functional cytochrome P450 1A enzymes are induced in mouse and human islets following pollutant exposure.
Autorzy :
Ibrahim M; Laboratory of Molecular and Cellular Medicine, Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
MacFarlane EM; Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.
Matteo G; Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.
Hoyeck MP; Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.
Rick KRC; Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.
Farokhi S; Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.
Copley CM; Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.
O'Dwyer S; Laboratory of Molecular and Cellular Medicine, Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
Bruin JE; Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada. .; Institute of Biochemistry, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada. .
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Źródło :
Diabetologia [Diabetologia] 2020 Jan; Vol. 63 (1), pp. 162-178. Date of Electronic Publication: 2019 Nov 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cytochrome P-450 CYP1A1/*metabolism
Cytochrome P-450 CYP1A2/*metabolism
Environmental Pollutants/*toxicity
Animals ; Blood Glucose/drug effects ; Cell Line ; Cytochrome P-450 CYP1A1/genetics ; Cytochrome P-450 CYP1A2/genetics ; Hep G2 Cells ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Polychlorinated Dibenzodioxins/toxicity ; Real-Time Polymerase Chain Reaction
Czasopismo naukowe
Tytuł :
Expression profile of cytochrome P450s and effects of polycyclic aromatic hydrocarbons and antiepileptic drugs on CYP1 expression in MOG-G-CCM cells.
Autorzy :
Ozawa S; Department of Pharmacy, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto 390-8621, Japan; Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621 Matsumoto, Japan.
Yamaori S; Department of Pharmacy, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto 390-8621, Japan; Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621 Matsumoto, Japan. Electronic address: .
Aikawa K; Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621 Matsumoto, Japan.
Kamijo S; Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621 Matsumoto, Japan.
Ohmori S; Department of Pharmacy, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto 390-8621, Japan; Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621 Matsumoto, Japan.
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Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118140. Date of Electronic Publication: 2020 Jul 27.
Typ publikacji :
Journal Article
MeSH Terms :
Anticonvulsants/*pharmacology
Cytochrome P-450 CYP1A1/*genetics
Cytochrome P-450 CYP1B1/*genetics
Polycyclic Aromatic Hydrocarbons/*pharmacology
Up-Regulation/*drug effects
Valproic Acid/*pharmacology
Astrocytes/drug effects ; Astrocytes/metabolism ; Cell Line, Tumor ; Humans ; Transcriptome/drug effects
Czasopismo naukowe
Tytuł :
2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Vascular Dysfunction That is Dependent on Perivascular Adipose and Cytochrome P4501A1 Expression.
Autorzy :
Walsh-Wilcox MT; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, 2703 Frontier Ave NE MSC09 5630, Albuquerque, NM, 87131, USA.
Kaye J; Teva Pharmaceutical Industries Ltd, Netanya, Israel.; Ayala Targeted Therapies, Rehovot, Israel.
Rubinstein E; Teva Pharmaceutical Industries Ltd, Netanya, Israel.
Walker MK; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, 2703 Frontier Ave NE MSC09 5630, Albuquerque, NM, 87131, USA. .
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Źródło :
Cardiovascular toxicology [Cardiovasc Toxicol] 2019 Dec; Vol. 19 (6), pp. 565-574.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adipose Tissue/*drug effects
Aorta/*drug effects
Arterial Pressure/*drug effects
Cytochrome P-450 CYP1A1/*metabolism
Hypertension/*chemically induced
Polychlorinated Dibenzodioxins/*toxicity
Vasoconstriction/*drug effects
Vasodilation/*drug effects
Adipose Tissue/enzymology ; Adipose Tissue/physiopathology ; Angiotensinogen/genetics ; Angiotensinogen/metabolism ; Animals ; Aorta/enzymology ; Aorta/physiopathology ; Cyclic Nucleotide Phosphodiesterases, Type 5/genetics ; Cyclic Nucleotide Phosphodiesterases, Type 5/metabolism ; Cytochrome P-450 CYP1A1/biosynthesis ; Cytochrome P-450 CYP1A1/deficiency ; Cytochrome P-450 CYP1A1/genetics ; Enzyme Induction ; Hypertension/enzymology ; Hypertension/genetics ; Hypertension/physiopathology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Time Factors
Czasopismo naukowe
Tytuł :
Bisphenol A affects estradiol metabolism by targeting CYP1A1 and CYP19A1 in human placental JEG-3 cells.
Autorzy :
Xu H; Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Zhang X; Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Ye Y; Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Li X; Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China; The Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Shanghai, China; Institute of Biomedical Science, Fudan University, Shanghai, China. Electronic address: .
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Źródło :
Toxicology in vitro : an international journal published in association with BIBRA [Toxicol In Vitro] 2019 Dec; Vol. 61, pp. 104615. Date of Electronic Publication: 2019 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Aromatase/*genetics
Benzhydryl Compounds/*toxicity
Cytochrome P-450 CYP1A1/*genetics
Endocrine Disruptors/*toxicity
Estradiol/*biosynthesis
Gene Expression Regulation/*drug effects
Phenols/*toxicity
Aromatase/metabolism ; Cell Line ; Cytochrome P-450 CYP1A1/metabolism ; Female ; Humans ; Placenta/cytology ; Placenta/metabolism ; Pregnancy
Czasopismo naukowe
Tytuł :
Mono-methylindoles induce CYP1A genes and inhibit CYP1A1 enzyme activity in human hepatocytes and HepaRG cells.
Autorzy :
Vyhlídalová B; Department of Cell Biology and Genetics, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic.
Poulíková K; Department of Cell Biology and Genetics, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic.
Bartoňková I; Department of Cell Biology and Genetics, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic.
Krasulová K; Department of Cell Biology and Genetics, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic; Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic.
Vančo J; Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic.
Trávníček Z; Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic.
Mani S; Department of Genetics and Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
Dvořák Z; Department of Cell Biology and Genetics, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic; Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacky University, Slechtitelu 27, 783 71, Olomouc, Czech Republic. Electronic address: .
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Źródło :
Toxicology letters [Toxicol Lett] 2019 Oct 01; Vol. 313, pp. 66-76. Date of Electronic Publication: 2019 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Cytochrome P-450 CYP1A1/*antagonists & inhibitors
Cytochrome P-450 CYP1A1/*biosynthesis
Cytochrome P-450 Enzyme Inducers/*pharmacology
Cytochrome P-450 Enzyme Inhibitors/*pharmacology
Hepatocytes/*drug effects
Indoles/*pharmacology
Aged ; Basic Helix-Loop-Helix Transcription Factors/agonists ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cell Line, Tumor ; Colonic Neoplasms/enzymology ; Cytochrome P-450 CYP1A1/genetics ; Dose-Response Relationship, Drug ; Enzyme Induction ; Female ; Hepatocytes/enzymology ; Humans ; Male ; Microsomes, Liver/drug effects ; Microsomes, Liver/enzymology ; Middle Aged ; Receptors, Aryl Hydrocarbon/agonists ; Receptors, Aryl Hydrocarbon/genetics ; Receptors, Aryl Hydrocarbon/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
Association of CYP1A1 rs1048943 variant with aggressive periodontitis and its interaction with hyperlipidemia on the periodontal status.
Autorzy :
Wang X; Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.
Li W; Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.
Song W; Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.; Third Clinical Division, Peking University School and Hospital of Stomatology, Beijing, China.
Xu L; Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.
Zhang L; Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.
Feng X; Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.
Lu R; Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.
Meng H; Department of Periodontology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Peking University School and Hospital of Stomatology, Beijing, China.; Third Clinical Division, Peking University School and Hospital of Stomatology, Beijing, China.
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Źródło :
Journal of periodontal research [J Periodontal Res] 2019 Oct; Vol. 54 (5), pp. 546-554. Date of Electronic Publication: 2019 Apr 29.
Typ publikacji :
Journal Article
MeSH Terms :
Aggressive Periodontitis*/genetics
Cytochrome P-450 CYP1A1*/genetics
Hyperlipidemias*/genetics
Alleles ; Case-Control Studies ; China ; Humans ; Triglycerides
Czasopismo naukowe
Tytuł :
Biological uptake, depuration and biochemical effects of diclofenac and carbamazepine in Carassius carassius.
Autorzy :
Nkoom M; Key Laboratory of Integrated Regulation and Resources Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing, 210098, China.
Lu G; Key Laboratory of Integrated Regulation and Resources Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing, 210098, China; Water Conservancy Project & Civil Engineering College, Tibet Agriculture & Animal Husbandry University, Linzhi, 860000, China. Electronic address: .
Liu J; Key Laboratory of Integrated Regulation and Resources Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing, 210098, China.
Dong H; Key Laboratory of Integrated Regulation and Resources Development of Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing, 210098, China.
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Dec 01; Vol. 205, pp. 111106. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
Carbamazepine/*toxicity
Carps/*metabolism
Diclofenac/*toxicity
Liver/*drug effects
Oxidative Stress/*drug effects
Water Pollutants, Chemical/*toxicity
Animals ; Antioxidants/metabolism ; Carbamazepine/metabolism ; Catalase/metabolism ; Cytochrome P-450 CYP1A1/metabolism ; Diclofenac/metabolism ; Glutathione Transferase/metabolism ; Inactivation, Metabolic ; Lipid Peroxidation/drug effects ; Liver/metabolism ; Malondialdehyde/metabolism ; Oxidation-Reduction ; Superoxide Dismutase/metabolism ; Water Pollutants, Chemical/metabolism
Czasopismo naukowe
Tytuł :
Effect of Genetic Polymorphisms on the Pharmacokinetics of Deferasirox in Healthy Chinese Subjects and an Artificial Neural Networks Model for Pharmacokinetic Prediction.
Autorzy :
Chen J; Center of Clinical Pharmacology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Xu Y; Center of Clinical Pharmacology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Lou H; Center of Clinical Pharmacology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Jiang B; Center of Clinical Pharmacology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Shao R; Center of Clinical Pharmacology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Yang D; Center of Clinical Pharmacology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Hu Y; Center of Clinical Pharmacology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Ruan Z; Center of Clinical Pharmacology, School of Medicine, The Second Affiliated Hospital of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China. .
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Źródło :
European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2020 Dec; Vol. 45 (6), pp. 761-770.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Neural Networks, Computer*
Deferasirox/*pharmacokinetics
Iron Chelating Agents/*pharmacokinetics
Adolescent ; Adult ; Area Under Curve ; Asian Continental Ancestry Group ; Cross-Over Studies ; Cytochrome P-450 CYP1A1/genetics ; Drug Compounding ; Female ; Glucuronosyltransferase/genetics ; Half-Life ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Multidrug Resistance-Associated Proteins/genetics ; Polymorphism, Genetic/genetics ; Polymorphism, Single Nucleotide ; Predictive Value of Tests ; Young Adult
Czasopismo naukowe
Tytuł :
Sublethal effects of carbendazim in Jenynsia multidentata detected by a battery of molecular, biochemical and genetic biomarkers.
Autorzy :
Götte JY; Facultad de Ciencias Exactas y Naturales, Departamento de Ciencias Marinas, Mar Del Plata, Argentina.
Carrizo JC; Universidad Nacional de Córdoba - CONICET, Facultad de Ciencias Químicas, Dto. Bioquímica Clínica-CIBICI, Córdoba, Argentina.
Panzeri AM; Laboratorio de Ecotoxicología, Instituto de Investigaciones Marinas y Costeras (IIMYC), Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Mar Del Plata (CONICET- UNMdP), Dean Funes 3350, 7600, Mar Del Plata, Buenos Aires, Argentina.
Amé MV; Universidad Nacional de Córdoba - CONICET, Facultad de Ciencias Químicas, Dto. Bioquímica Clínica-CIBICI, Córdoba, Argentina.
Menone ML; Laboratorio de Ecotoxicología, Instituto de Investigaciones Marinas y Costeras (IIMYC), Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad Nacional de Mar Del Plata (CONICET- UNMdP), Dean Funes 3350, 7600, Mar Del Plata, Buenos Aires, Argentina. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Dec 01; Vol. 205, pp. 111157. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article
MeSH Terms :
Benzimidazoles/*toxicity
Carbamates/*toxicity
Cyprinodontiformes/*metabolism
Cytokines/*metabolism
Micronuclei, Chromosome-Defective/*chemically induced
Oxidative Stress/*drug effects
Water Pollutants, Chemical/*toxicity
ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Animals ; Antioxidants/metabolism ; Biomarkers/metabolism ; Cyprinodontiformes/genetics ; Cyprinodontiformes/immunology ; Cytochrome P-450 CYP1A1/genetics ; Ecosystem ; Fresh Water/chemistry ; Gills/drug effects ; Gills/metabolism ; Liver/drug effects ; Liver/metabolism ; Oxidative Stress/genetics ; Oxidative Stress/immunology
Czasopismo naukowe
Tytuł :
The sulfate metabolite of 3,3'-dichlorobiphenyl (PCB-11) impairs Cyp1a activity and increases hepatic neutral lipids in zebrafish larvae (Danio rerio).
Autorzy :
Roy MA; Department of Environmental Health Sciences, University of Massachusetts Amherst, Amherst, MA, 01003, USA.
Duche PR; Department of Environmental Health Sciences, University of Massachusetts Amherst, Amherst, MA, 01003, USA.
Timme-Laragy AR; Department of Environmental Health Sciences, University of Massachusetts Amherst, Amherst, MA, 01003, USA. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2020 Dec; Vol. 260, pp. 127609. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji :
Journal Article
MeSH Terms :
Polychlorinated Biphenyls/*toxicity
Zebrafish/*physiology
Animals ; Benzo(a)pyrene/metabolism ; Cytochrome P-450 CYP1A1/metabolism ; Embryo, Nonmammalian/metabolism ; Larva/metabolism ; Lipids ; Liver/metabolism ; Polychlorinated Biphenyls/metabolism ; Sulfates/metabolism ; Zebrafish/metabolism
Czasopismo naukowe
Tytuł :
Age-dependent vulnerability of the ovary to AhR-mediated TCDD action before puberty: Evidence from mouse models.
Autorzy :
Devillers MM; Université de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, F-75013, Paris, France.
Petit F; Université de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, F-75013, Paris, France.
Giton F; AP-HP, Pôle biologie-Pathologie Henri Mondor, INSERM IMRB U955, Créteil, France.
François CM; Université de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, F-75013, Paris, France.
Juricek L; INSERM UMR-S 1124, Université de Paris, Paris, France.
Coumoul X; INSERM UMR-S 1124, Université de Paris, Paris, France.
Magre S; Université de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, F-75013, Paris, France.
Cohen-Tannoudji J; Université de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, F-75013, Paris, France.
Guigon CJ; Université de Paris, BFA, UMR 8251, CNRS, ERL U1133, Inserm, F-75013, Paris, France. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2020 Nov; Vol. 258, pp. 127361. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Ovary/*physiology
Polychlorinated Dibenzodioxins/*toxicity
Receptors, Aryl Hydrocarbon/*metabolism
Animals ; Cytochrome P-450 CYP1A1/metabolism ; Endocrine Disruptors/metabolism ; Estradiol/metabolism ; Estrogens/pharmacology ; Female ; Granulosa Cells/drug effects ; Ligands ; Mice ; Mice, Inbred C57BL ; Ovary/drug effects ; Polychlorinated Dibenzodioxins/metabolism ; Sexual Maturation/drug effects ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Hepatic oxidative stress, DNA damage and apoptosis in adult zebrafish following sub-chronic exposure to BDE-47 and BDE-153.
Autorzy :
Meng S; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi, China.; Key Laboratory of Fishery Eco-environment Assessment and Resource Conservation in Middle and Lower Reaches of the Yangtze River, CAFS, Wuxi, China.
Chen X; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi, China.; Key Laboratory of Fishery Eco-environment Assessment and Resource Conservation in Middle and Lower Reaches of the Yangtze River, CAFS, Wuxi, China.
Gyimah E; School of Environmental and Safety Engineering, Jiangsu University, Zhenjiang, China.
Xu H; School of Environmental and Safety Engineering, Jiangsu University, Zhenjiang, China.
Chen J; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi, China.; Key Laboratory of Fishery Eco-environment Assessment and Resource Conservation in Middle and Lower Reaches of the Yangtze River, CAFS, Wuxi, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2020 Nov; Vol. 35 (11), pp. 1202-1211. Date of Electronic Publication: 2020 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
Halogenated Diphenyl Ethers/*toxicity
Polybrominated Biphenyls/*toxicity
Water Pollutants, Chemical/*toxicity
Animals ; Antioxidants/metabolism ; Apoptosis/drug effects ; Caspase 3 ; Comet Assay ; Cytochrome P-450 CYP1A1/metabolism ; DNA Damage ; Halogenated Diphenyl Ethers/metabolism ; Hepatocytes/metabolism ; Liver/metabolism ; Oxidative Stress/drug effects ; Zebrafish/metabolism
Czasopismo naukowe

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