Temat: "CYP1A1" - OpacWWW - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: Genetic polymorphisms of CYP1A, CYP1B, CYP2C and risk of cervical cancer among rural population of Maharashtra: Findings from a hospital-based case-control study.
Autorzy:: Datkhile KD; Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences 'Deemed to be University', Taluka-Karad, Dist- Satara, Maharashtra, India.
Patil SR; Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences 'Deemed to be University', Taluka-Karad, Dist- Satara, Maharashtra, India.
Patil MN; Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences 'Deemed to be University', Taluka-Karad, Dist- Satara, Maharashtra, India.
Durgawale PP; Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences 'Deemed to be University', Taluka-Karad, Dist- Satara, Maharashtra, India.
Jagdale NJ; Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences 'Deemed to be University', Taluka-Karad, Dist- Satara, Maharashtra, India.
Deshmukh VN; Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences 'Deemed to be University', Taluka-Karad, Dist- Satara, Maharashtra, India.
More AL; Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences 'Deemed to be University', Taluka-Karad, Dist- Satara, Maharashtra, India.
Gudur RA; Department of Oncology, Krishna Institute of Medical Sciences 'Deemed to be University', Taluka-Karad, Dist- Satara, Maharashtra, India.
Gudur AK; Department of Oncology, Krishna Institute of Medical Sciences 'Deemed to be University', Taluka-Karad, Dist- Satara, Maharashtra, India.; Pokaż więcej
Źródło:: Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Oct 01; Vol. 19 (7), pp. 1925-1930. Date of Electronic Publication: 2023 Mar 26.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme System*
Uterine Cervical Neoplasms*/epidemiology
Uterine Cervical Neoplasms*/genetics
Female ; Humans ; Case-Control Studies ; Cytochrome P-450 CYP1A1 ; Cytochrome P-450 CYP2C19/genetics ; Cytochrome P-450 CYP2C8 ; Cytochrome P-450 CYP2C9 ; India/epidemiology ; Polymorphism, Single Nucleotide ; Rural Population

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Skocz do pozycji: 2.

Tytuł:: Pharmacokinetic changes of clozapine and norclozapine in a rat model of non-alcoholic fatty liver disease induced by orotic acid.
Autorzy:: Li Z; College of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, South Korea.
Lee SH; College of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, South Korea.
Jeong HJ; College of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, South Korea.
Kang HE; College of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea, Bucheon, South Korea.; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Mar; Vol. 51 (3), pp. 324-334. Date of Electronic Publication: 2020 Nov 29.
Typ publikacji:: Journal Article
MeSH Terms:: Clozapine/*analogs & derivatives
Clozapine/*pharmacokinetics
Cytochrome P-450 Enzyme System/*metabolism
Non-alcoholic Fatty Liver Disease/*enzymology
Animals ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1A2/metabolism ; Non-alcoholic Fatty Liver Disease/chemically induced ; Orotic Acid ; Rats

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Skocz do pozycji: 3.

Tytuł:: Liquid chromatography-tandem mass spectrometry analysis of oxidation of 2'-, 3'-, 4'- and 6-hydroxyflavanones by human cytochrome P450 enzymes.
Autorzy:: Shimada T; Laboratory of Cellular and Molecular Biology, Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan.
Nagayoshi H; Division of Food Sanitation, Osaka Institute of Public Health, Osaka, Japan.
Murayama N; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan.
Takenaka S; Graduate School of Comprehensive Rehabilitation, Osaka Prefecture University, Habikino, Osaka, Japan.
Katahira J; Laboratory of Cellular and Molecular Biology, Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan.
Kim V; Department of Biological Sciences, Konkuk University, Seoul, Korea.
Kim D; Department of Biological Sciences, Konkuk University, Seoul, Korea.
Komori M; Laboratory of Cellular and Molecular Biology, Veterinary Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan.
Yamazaki H; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan.
Guengerich FP; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA.; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Feb; Vol. 51 (2), pp. 139-154. Date of Electronic Publication: 2020 Oct 23.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme System/*physiology
Flavonoids/*chemistry
Chromatography, Liquid ; Cytochrome P-450 CYP1A1 ; Cytochrome P-450 CYP2A6 ; Flavanones ; Flavones ; Humans ; Hydroxylation ; Molecular Docking Simulation ; Oxidation-Reduction ; Tandem Mass Spectrometry

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Skocz do pozycji: 4.

Tytuł:: An electron transfer competent structural ensemble of membrane-bound cytochrome P450 1A1 and cytochrome P450 oxidoreductase.
Autorzy:: Mukherjee G; Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS), Schloss-Wolfsbrunnenweg 35, 69118, Heidelberg, Germany.; Zentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, INF 282, 69120, Heidelberg, Germany.; Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, INF 368, 69120, Heidelberg, Germany.
Nandekar PP; Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS), Schloss-Wolfsbrunnenweg 35, 69118, Heidelberg, Germany.; Zentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, INF 282, 69120, Heidelberg, Germany.; Schrodinger Inc., #147, 3rd Floor, Jawaharlal Nehru Main Road, Above State Bank of India, Channasandra, 5th Stage, RR Nagar, Bengaluru, India, 560098.
Wade RC; Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS), Schloss-Wolfsbrunnenweg 35, 69118, Heidelberg, Germany. .; Zentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, INF 282, 69120, Heidelberg, Germany. .; Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, INF 368, 69120, Heidelberg, Germany. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2021 Jan 08; Vol. 4 (1), pp. 55. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Membrane/*metabolism
Cytochrome P-450 CYP1A1/*metabolism
Cytochrome P-450 Enzyme System/*metabolism
Electron Transport ; Humans ; Molecular Dynamics Simulation ; Protein Domains

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Skocz do pozycji: 5.

Tytuł:: Effects of silymarin on p65 NF-κB, p38 MAPK and CYP450 in LPS-induced hoof dermal inflammatory cells of dairy cows.
Autorzy:: Tian MY; College of Veterinary Medicine, Hebei Agricultural University, 2596 Lekai South Street, Baoding, 071001, Hebei, China.
Fan JH; College of Veterinary Medicine, Hebei Agricultural University, 2596 Lekai South Street, Baoding, 071001, Hebei, China.
Zhuang ZW; Shandong New Hope Liuhe Co. Ltd, Qingdao, 266000, Shandong, China.
Dai F; College of Veterinary Medicine, Hebei Agricultural University, 2596 Lekai South Street, Baoding, 071001, Hebei, China.
Wang CY; College of Veterinary Medicine, Hebei Agricultural University, 2596 Lekai South Street, Baoding, 071001, Hebei, China.
Hou HT; College of Veterinary Medicine, Hebei Agricultural University, 2596 Lekai South Street, Baoding, 071001, Hebei, China.
Ma YZ; College of Veterinary Medicine, Hebei Agricultural University, 2596 Lekai South Street, Baoding, 071001, Hebei, China. .; Pokaż więcej
Źródło:: BMC veterinary research [BMC Vet Res] 2019 Apr 30; Vol. 15 (1), pp. 127. Date of Electronic Publication: 2019 Apr 30.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme System/*metabolism
Hoof and Claw/*cytology
Silymarin/*pharmacology
Transcription Factor RelA/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Animals ; Cattle ; Cell Survival/drug effects ; Cells, Cultured ; Cytochrome P-450 CYP1A1/genetics ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP3A/genetics ; Cytochrome P-450 CYP3A/metabolism ; Cytochrome P-450 Enzyme System/genetics ; Dermis/cytology ; Dermis/drug effects ; Gene Expression Regulation/drug effects ; Hoof and Claw/drug effects ; Inflammation/chemically induced ; Interleukin-1beta/metabolism ; Lipopolysaccharides/toxicity ; Phosphorylation ; Transcription Factor RelA/genetics ; Tumor Necrosis Factor-alpha/metabolism ; p38 Mitogen-Activated Protein Kinases/genetics

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Skocz do pozycji: 6.

Tytuł:: Modulation of Rat Hepatic CYP1A and 2C Activity by Honokiol and Magnolol: Differential Effects on Phenacetin and Diclofenac Pharmacokinetics In Vivo.
Autorzy:: Kim SB; New Drug Development Center, Daegu‒Gyeongbuk Medical Innovation Foundation, Daegu 41061, Korea. .; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea. .
Kim KS; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea. .
Ryu HM; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea. .
Hong SH; Biomedicine Lab, CKD Research Institute, Gyeonggi 16995, Korea. .
Kim BK; New Drug Development Center, Daegu‒Gyeongbuk Medical Innovation Foundation, Daegu 41061, Korea. .
Kim DD; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea. .
Park JW; Department of Pharmacy, College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Jeonnam 58554, Korea. .
Yoon IS; Department of Manufacturing Pharmacy, College of Pharmacy, Pusan National University, Busan 46241, Korea. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 Jun 17; Vol. 23 (6). Date of Electronic Publication: 2018 Jun 17.
Typ publikacji:: Journal Article
MeSH Terms:: Biphenyl Compounds/*administration & dosage
Cytochrome P-450 CYP1A1/*metabolism
Cytochrome P-450 Enzyme System/*metabolism
Diclofenac/*pharmacokinetics
Lignans/*administration & dosage
Liver/*enzymology
Phenacetin/*pharmacokinetics
Administration, Intravenous ; Animals ; Biphenyl Compounds/pharmacology ; Chromatography, High Pressure Liquid ; Drug Interactions ; Gene Expression Regulation/drug effects ; Lignans/pharmacology ; Liver/cytology ; Microsomes, Liver/enzymology ; Molecular Structure ; Rats ; Rats, Sprague-Dawley

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Skocz do pozycji: 7.

Tytuł:: Developmental changes in drug-metabolizing enzyme expression during metamorphosis of Xenopus tropicalis.
Autorzy:: Mori J; Graduate School of Biomedical and Health Science, Hiroshima University.
Sanoh S; Graduate School of Biomedical and Health Science, Hiroshima University.
Kashiwagi K; Amphibian Research Center, Hiroshima University.
Hanada H; Amphibian Research Center, Hiroshima University.
Shigeta M; Graduate School of Science, Hiroshima University.
Suzuki KT; Graduate School of Science, Hiroshima University.
Yamamoto T; Graduate School of Science, Hiroshima University.
Kotake Y; Graduate School of Biomedical and Health Science, Hiroshima University.
Sugihara K; Faculty of Pharmaceutical Sciences, Hiroshima International University.
Kitamura S; Nihon Pharmaceutical University.
Kashiwagi A; Amphibian Research Center, Hiroshima University.
Ohta S; Graduate School of Biomedical and Health Science, Hiroshima University.; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2017; Vol. 42 (5), pp. 605-613.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme System/*genetics
Cytochrome P-450 Enzyme System/*metabolism
Gene Expression/*genetics
Gene Expression Regulation, Developmental/*genetics
Metamorphosis, Biological/*genetics
Thyroid Hormones/*metabolism
Thyroid Hormones/*physiology
Xenopus/*genetics
Xenopus/*physiology
Animals ; Cytochrome P-450 CYP1A1/genetics ; Cytochrome P-450 CYP1A1/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, Cytoplasmic and Nuclear/metabolism

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Skocz do pozycji: 8.

Tytuł:: Effects of chronic exposure to tributyltin on tissue-specific cytochrome P450 1 regulation in juvenile common carp.
Autorzy:: Li ZH; a Observation Station for Fishery Resource and Environment in Upper-Middle Reaches of Yangtze River (Ministry of Agriculture), Key Laboratory of Freshwater Biodiversity Conservation (Ministry of Agriculture), Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences , Wuhan , China .; b University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses , Vodňany , Czech Republic .
Zhong LQ; a Observation Station for Fishery Resource and Environment in Upper-Middle Reaches of Yangtze River (Ministry of Agriculture), Key Laboratory of Freshwater Biodiversity Conservation (Ministry of Agriculture), Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences , Wuhan , China .
Mu WN; a Observation Station for Fishery Resource and Environment in Upper-Middle Reaches of Yangtze River (Ministry of Agriculture), Key Laboratory of Freshwater Biodiversity Conservation (Ministry of Agriculture), Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences , Wuhan , China .; c College of Fisheries, Huazhong Agricultural University , Wuhan , Hubei , China , and.
Wu YH; a Observation Station for Fishery Resource and Environment in Upper-Middle Reaches of Yangtze River (Ministry of Agriculture), Key Laboratory of Freshwater Biodiversity Conservation (Ministry of Agriculture), Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences , Wuhan , China .; d Key Laboratory of Aquatic Science of Chongqing, School of Life Science, Southwest University , Chongqing , China.; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2016; Vol. 46 (6), pp. 511-5. Date of Electronic Publication: 2015 Oct 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Environmental Exposure*
Carps/*genetics
Cytochrome P-450 Enzyme System/*genetics
Gene Expression Regulation, Enzymologic/*drug effects
Organ Specificity/*drug effects
Trialkyltin Compounds/*toxicity
Animals ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 Enzyme System/metabolism ; Linear Models ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

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Skocz do pozycji: 9.

Tytuł:: Endothelial cell cytochrome P450 1A1 and 1B1: up-regulation by shear stress.
Autorzy:: Eskin SG; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30309, USA. />Turner NA
McIntire LV; Pokaż więcej
Źródło:: Endothelium : journal of endothelial cell research [Endothelium] 2004 Jan-Feb; Vol. 11 (1), pp. 1-10.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Cytochrome P-450 CYP1A1/*genetics
Cytochrome P-450 Enzyme System/*genetics
Endothelial Cells/*metabolism
Regional Blood Flow/*physiology
Up-Regulation/*physiology
Aryl Hydrocarbon Hydroxylases ; Cells, Cultured ; Connective Tissue Growth Factor ; Culture Media, Conditioned/pharmacology ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1B1 ; Cytochrome P-450 Enzyme System/metabolism ; Endothelial Cells/drug effects ; Endothelin-1/genetics ; Enzyme Inhibitors/pharmacology ; Humans ; Immediate-Early Proteins/genetics ; Infant, Newborn ; Intercellular Signaling Peptides and Proteins/genetics ; RNA, Messenger/drug effects ; RNA, Messenger/metabolism ; Stress, Mechanical ; Up-Regulation/drug effects ; beta-Naphthoflavone/pharmacology

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Skocz do pozycji: 10.

Tytuł:: Immunochemical detection of cytochrome P450 enzymes in small intestine microsomes of male and female untreated juvenile cynomolgus monkeys.
Autorzy:: Uehara S; Pharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd. , Kainan, Wakayama , Japan .
Murayama N
Nakanishi Y
Nakamura C
Hashizume T
Zeldin DC
Yamazaki H
Uno Y; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2014 Sep; Vol. 44 (9), pp. 769-74. Date of Electronic Publication: 2014 Mar 05.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:: Cytochrome P-450 Enzyme System/*isolation & purification
Intestine, Small/*enzymology
Microsomes/*enzymology
Alcohol Oxidoreductases/isolation & purification ; Alcohol Oxidoreductases/metabolism ; Animals ; Cytochrome P-450 CYP1A1/isolation & purification ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP2C19/isolation & purification ; Cytochrome P-450 CYP2C19/metabolism ; Cytochrome P-450 CYP2C9/isolation & purification ; Cytochrome P-450 CYP2C9/metabolism ; Cytochrome P-450 CYP2J2 ; Cytochrome P-450 CYP3A/isolation & purification ; Cytochrome P-450 CYP3A/metabolism ; Cytochrome P-450 Enzyme System/metabolism ; Female ; Macaca fascicularis ; Male

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Skocz do pozycji: 11.

Tytuł:: Use of a quantitative real-time reverse transcription-polymerase chain reaction method to study the induction of CYP1A, CYP2B and CYP4A forms in precision-cut rat liver slices.
Autorzy:: Pan J; Wyeth-Ayerst Research, Drug Metabolism Division, CN8000, Princeton, NJ 08543-8000, USA.
Xiang Q
Renwick AB
Price RJ
Ball SE
Kao J
Scatina JA
Lake BG; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2002 Sep; Vol. 32 (9), pp. 739-47.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Up-Regulation*
Cytochrome P-450 CYP1A1/*biosynthesis
Cytochrome P-450 CYP1A2/*biosynthesis
Cytochrome P-450 CYP2B1/*biosynthesis
Cytochrome P-450 Enzyme System/*biosynthesis
Liver/*enzymology
Animals ; Aroclors/pharmacology ; Cytochrome P-450 CYP1A1/genetics ; Cytochrome P-450 CYP1A2/genetics ; Cytochrome P-450 CYP2B1/genetics ; Cytochrome P-450 Enzyme System/genetics ; Cytochrome P450 Family 4 ; Environmental Pollutants ; Excitatory Amino Acid Antagonists/pharmacology ; Male ; Mutagens ; Phenobarbital/pharmacology ; Pyrimidines/pharmacology ; RNA/metabolism ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Reverse Transcriptase Polymerase Chain Reaction ; Time Factors

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Skocz do pozycji: 12.

Tytuł:: Differential effects of two lots of aroclor 1254 on enzyme induction, thyroid hormones, and oxidative stress.
Autorzy:: Burgin DE; Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina, USA. />Diliberto JJ
Derr-Yellin EC
Kannan N
Kodavanti PR
Birnbaum LS; Pokaż więcej
Źródło:: Environmental health perspectives [Environ Health Perspect] 2001 Nov; Vol. 109 (11), pp. 1163-8.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:: Oxidative Stress*
Antithyroid Agents/*adverse effects
Chlorodiphenyl (54% Chlorine)/*adverse effects
Cytochrome P-450 CYP1A1/*metabolism
Cytochrome P-450 CYP2B1/*metabolism
Cytochrome P-450 Enzyme System/*metabolism
Oxidoreductases/*metabolism
Thyroxine/*blood
Administration, Oral ; Animals ; Cytochrome P-450 CYP1A1/drug effects ; Cytochrome P-450 CYP2B1/drug effects ; Cytochrome P-450 Enzyme System/drug effects ; Enzyme Induction ; Isomerism ; Liver/drug effects ; Liver/enzymology ; Male ; Oxidoreductases/drug effects ; Rats ; Rats, Long-Evans ; Reproducibility of Results ; Thyroxine/drug effects

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Skocz do pozycji: 13.

Tytuł:: Important role of CYP2J2 in protein kinase inhibitor degradation: a possible role in intratumor drug disposition and resistance.
Autorzy:: Narjoz C; Université Paris Descartes, INSERM UMR S-U775, Sorbonne Paris Cité, Paris, France; Hôpital Européen Georges Pompidou, Service de Biochimie, Unité Fonctionnelle de Pharmacogénétique et Oncologie Moléculaire, Paris, France.
Favre A; Quantitative Mass Spectrometry Facility, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
McMullen J; Quantitative Mass Spectrometry Facility, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Kiehl P; Quantitative Mass Spectrometry Facility, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Montemurro M; University Hospital Zürich, Oncology, Zürich, Switzerland.
Figg WD; Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Beaune P; Université Paris Descartes, INSERM UMR S-U775, Sorbonne Paris Cité, Paris, France; Hôpital Européen Georges Pompidou, Service de Biochimie, Unité Fonctionnelle de Pharmacogénétique et Oncologie Moléculaire, Paris, France.
de Waziers I; Université Paris Descartes, INSERM UMR S-U775, Sorbonne Paris Cité, Paris, France.
Rochat B; Quantitative Mass Spectrometry Facility, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2014 May 12; Vol. 9 (5), pp. e95532. Date of Electronic Publication: 2014 May 12 (Print Publication: 2014).
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme System/*metabolism
Protein Kinase Inhibitors/*metabolism
Benzamides/metabolism ; Carcinoma, Hepatocellular/genetics ; Cell Line, Tumor ; Cytochrome P-450 CYP1A1/genetics ; Cytochrome P-450 CYP1B1/genetics ; Cytochrome P-450 CYP2J2 ; Cytochrome P-450 CYP3A/genetics ; Cytochrome P-450 Enzyme System/genetics ; Dasatinib ; Hep G2 Cells ; Humans ; Imatinib Mesylate ; Indoles/metabolism ; Liver Neoplasms/genetics ; Niacinamide/analogs & derivatives ; Niacinamide/metabolism ; Phenylurea Compounds/metabolism ; Piperazines/metabolism ; Pyrimidines/metabolism ; Pyrroles/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Sorafenib ; Sunitinib ; Thiazoles/metabolism