Temat: "CYP1B1" - OpacWWW - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: CYP1B1 affects the integrity of the blood-brain barrier and oxidative stress in the striatum: An investigation of manganese-induced neurotoxicity.
Autorzy:: Wu J; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.; Department of Pharmacy, Taikang Tongji (Wuhan) Hospital, Wuhu, China.
Li Y; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.; Department of Pharmacy, The First Affiliated Hospital of Wannan Medical College, Wuhu, China.
Tian S; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Na S; Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei, China.
Wei H; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Wu Y; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Yang Y; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Shen Z; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Ding J; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Bao S; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Liu S; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Li L; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Feng R; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Zhu Y; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
He C; Demonstration Center for Experimental Basic Medicine Education, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Yue J; Department of Pharmacology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.; Hubei Province Key Laboratory of Allergy and Immunology, Wuhan, China.; Pokaż więcej
Źródło:: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14633.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Blood-Brain Barrier*/metabolism
Cytochrome P-450 CYP1B1*/metabolism
Neuroblastoma*
Animals ; Humans ; Mice ; alpha-Synuclein/metabolism ; Biotin/metabolism ; Dopamine/metabolism ; Endothelial Cells/metabolism ; Manganese/toxicity ; Oxidative Stress

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Skocz do pozycji: 2.

Tytuł:: Genotyping of the rs1800440 Polymorphism in CYP1B1 Gene and the rs9258883 Polymorphism in HLA-B Gene in a Spanish Cohort of 223 Patients with Frontal Fibrosing Alopecia.
Autorzy:: Saceda-Corralo D; Dermatology Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain. .
Ortega-Quijano D; Dermatology Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Muñoz-Martín G; UCA Translational Genomics, University Hospital Ramón y Cajal. Madrid, Spain.
Moreno-Arrones ÓM; Dermatology Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Pindado-Ortega C; Dermatology Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Rayinda T; St John's Institute of Dermatology, King's College London, London, UK.
Melián-Olivera A; Dermatology Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Azcárraga-Llobet C; Dermatology Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Burgos-Blasco P; Dermatology Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.
Castañeda-Bermúdez ME; Jalisco Dermatological Institute, Guadalajara, Mexico.
Del Castillo FJ; UCA Translational Genomics, University Hospital Ramón y Cajal. Madrid, Spain.
Vañó-Galván S; Dermatology Department, University Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Pokaż więcej
Źródło:: Acta dermato-venereologica [Acta Derm Venereol] 2023 Sep 18; Vol. 103, pp. adv9604. Date of Electronic Publication: 2023 Sep 18.
Typ publikacji:: Journal Article
MeSH Terms:: Alopecia*/diagnosis
Alopecia*/genetics
Cytochrome P-450 CYP1B1*/genetics
HLA-B Antigens*/genetics
Humans ; Cross-Sectional Studies ; Genotype ; Heterozygote

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Skocz do pozycji: 3.

Tytuł:: AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors.
Autorzy:: Larsen MC; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Rondelli CM; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
Almeldin A; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Song YS; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
N'Jai A; Department of Pathobiological Sciences, University of Wisconsin, Madison, WI 53706, USA.
Alexander DL; Institute for the Biology of Stem Cells, University of California, Santa Cruz, CA 95064, USA.
Forsberg EC; Institute for the Biology of Stem Cells, University of California, Santa Cruz, CA 95064, USA.
Sheibani N; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Jefcoate CR; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 28; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:: Journal Article
MeSH Terms:: Mesenchymal Stem Cells*/metabolism
Polycyclic Aromatic Hydrocarbons*/metabolism
Receptors, Odorant*
Animals ; Mice ; Bone Marrow/metabolism ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1B1/genetics ; Cytochrome P-450 CYP1B1/metabolism ; Oxygen ; Reactive Oxygen Species ; Receptors, Aryl Hydrocarbon/metabolism

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Skocz do pozycji: 4.

Tytuł:: Regulation of Benzo[a]pyrene-Induced Hepatic Lipid Accumulation through CYP1B1-Induced mTOR-Mediated Lipophagy.
Autorzy:: Bu KB; Department of Life Science, Dongguk University-Seoul, Goyang 10326, Republic of Korea.
Kim M; Department of Life Science, Dongguk University-Seoul, Goyang 10326, Republic of Korea.
Shin MK; Department of Life Science, Dongguk University-Seoul, Goyang 10326, Republic of Korea.
Lee SH; Department of Life Science, Dongguk University-Seoul, Goyang 10326, Republic of Korea.
Sung JS; Department of Life Science, Dongguk University-Seoul, Goyang 10326, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 22; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:: Journal Article
MeSH Terms:: Benzo(a)pyrene*/toxicity
Liver*/metabolism
Cytochrome P-450 CYP1B1/genetics ; Cytochrome P-450 Enzyme System ; TOR Serine-Threonine Kinases/genetics ; Receptors, Aryl Hydrocarbon/metabolism ; Autophagy ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors ; Lipids ; Cytochrome P-450 CYP1A1/genetics

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Skocz do pozycji: 5.

Tytuł:: CircPPAP2B controls metastasis of clear cell renal cell carcinoma via HNRNPC-dependent alternative splicing and targeting the miR-182-5p/CYP1B1 axis.
Autorzy:: Zheng Z; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zeng X; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zhu Y; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Leng M; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zhang Z; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Wang Q; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Liu X; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Zeng S; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Xiao Y; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Hu C; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Pang S; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Wang T; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Xu B; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Peng P; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Li F; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China. .
Tan W; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China. .; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2024 Jan 06; Vol. 23 (1), pp. 4. Date of Electronic Publication: 2024 Jan 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Renal Cell*/genetics
MicroRNAs*/genetics
Kidney Neoplasms*/genetics
Humans ; Alternative Splicing ; RNA, Circular/genetics ; Heterogeneous-Nuclear Ribonucleoproteins ; Polypyrimidine Tract-Binding Protein ; Cytochrome P-450 CYP1B1 ; Heterogeneous-Nuclear Ribonucleoprotein Group C/genetics

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Skocz do pozycji: 6.

Tytuł:: CYP1B1-catalyzed 4-OHE2 promotes the castration resistance of prostate cancer stem cells by estrogen receptor α-mediated IL6 activation.
Autorzy:: Lin Q; Department of Biochemistry and Molecular Biology, College of Life Sciences, Bioactive Materials Key Lab of the Ministry of Education, Nankai University, Tianjin, 300071, China.
Cao J; Department of Biochemistry and Molecular Biology, College of Life Sciences, Bioactive Materials Key Lab of the Ministry of Education, Nankai University, Tianjin, 300071, China.; Tianjin Key Lab of Human Development and Reproductive Regulation, Tianjin Central Hospital of Obstetrics and Gynecology, Nankai University, Tianjin, 300071, China.
Du X; Department of Biochemistry and Molecular Biology, College of Life Sciences, Bioactive Materials Key Lab of the Ministry of Education, Nankai University, Tianjin, 300071, China.
Yang K; Department of Urology, Second Hospital of Tianjin Medical University, Tianjin, 300211, China.
Yang X; Department of Biochemistry and Molecular Biology, College of Life Sciences, Bioactive Materials Key Lab of the Ministry of Education, Nankai University, Tianjin, 300071, China.
Liang Z; Department of Biochemistry and Molecular Biology, College of Life Sciences, Bioactive Materials Key Lab of the Ministry of Education, Nankai University, Tianjin, 300071, China.
Shi J; Department of Biochemistry and Molecular Biology, College of Life Sciences, Bioactive Materials Key Lab of the Ministry of Education, Nankai University, Tianjin, 300071, China. .
Zhang J; Department of Biochemistry and Molecular Biology, College of Life Sciences, Bioactive Materials Key Lab of the Ministry of Education, Nankai University, Tianjin, 300071, China. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2022 Mar 15; Vol. 20 (1), pp. 31. Date of Electronic Publication: 2022 Mar 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:: Cytochrome P-450 CYP1B1*/metabolism
Estrogen Receptor alpha*/metabolism
Interleukin-6*/metabolism
Prostatic Neoplasms, Castration-Resistant*/drug therapy
Androgen Antagonists ; Androgens ; Castration ; Catalysis ; Cell Line, Tumor ; Estradiol/pharmacology ; Humans ; Male ; Neoplastic Stem Cells/metabolism ; Prostate/metabolism

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Skocz do pozycji: 7.

Tytuł:: Human Adult Renal Progenitor Cells Prevent Cisplatin-Nephrotoxicity by Inducing CYP1B1 Overexpression and miR-27b-3p Down-Regulation through Extracellular Vesicles.
Autorzy:: Franzin R; Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, 70124 Bari, Italy.; MIRROR-Medical Institute for Regeneration, Repairing and Organ Replacement, Interdepartmental Center, University of Bari Aldo Moro, 70124 Bari, Italy.
Stasi A; Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, 70124 Bari, Italy.; MIRROR-Medical Institute for Regeneration, Repairing and Organ Replacement, Interdepartmental Center, University of Bari Aldo Moro, 70124 Bari, Italy.
De Palma G; Institutional BioBank, Experimental Oncology and Biobank Management Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.
Picerno A; Department Interdisciplinary of Medicine (DIM), University of Bari, 70124 Bari, Italy.
Curci C; Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, 70124 Bari, Italy.
Sebastiano S; Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, 70124 Bari, Italy.
Campioni M; Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, 70124 Bari, Italy.
Cicirelli A; Department Interdisciplinary of Medicine (DIM), University of Bari, 70124 Bari, Italy.
Rizzo A; Struttura Semplice Dipartimentale di Oncologia Medica per la Presa in Carico Globale del Paziente Oncologico 'Don Tonino Bello', IRCCS Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, 70124 Bari, Italy.
Di Lorenzo VF; Urology Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', 70124 Bari, Italy.
Pontrelli P; Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, 70124 Bari, Italy.
Pertosa GB; Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, 70124 Bari, Italy.
Castellano G; Unit of Nephrology, Dialysis and Renal Transplantation, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico di Milano, 20122 Milan, Italy.
Gesualdo L; Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, 70124 Bari, Italy.; MIRROR-Medical Institute for Regeneration, Repairing and Organ Replacement, Interdepartmental Center, University of Bari Aldo Moro, 70124 Bari, Italy.
Sallustio F; Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari, 70124 Bari, Italy.; MIRROR-Medical Institute for Regeneration, Repairing and Organ Replacement, Interdepartmental Center, University of Bari Aldo Moro, 70124 Bari, Italy.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Jun 17; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cisplatin*/adverse effects
Cisplatin*/metabolism
Cisplatin*/pharmacology
Kidney*/drug effects
Kidney*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Stem Cells*/metabolism
Adult ; Humans ; Cytochrome P-450 CYP1B1/genetics ; Cytochrome P-450 CYP1B1/metabolism ; Down-Regulation/genetics ; Extracellular Vesicles/genetics ; Extracellular Vesicles/metabolism

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Skocz do pozycji: 8.

Tytuł:: Hippocampal Expression of Cytochrome P450 1B1 in Penetrating Traumatic Brain Injury.
Autorzy:: Lidin E; Experimental Traumatology Unit, Department of Neuroscience, Karolinska Institute, 171 77 Stockholm, Sweden.
Sköld MK; Experimental Traumatology Unit, Department of Neuroscience, Karolinska Institute, 171 77 Stockholm, Sweden.; Section of Neurosurgery, Department of Neuroscience, Uppsala University, 751 85 Uppsala, Sweden.
Angéria M; Experimental Traumatology Unit, Department of Neuroscience, Karolinska Institute, 171 77 Stockholm, Sweden.
Davidsson J; Department of Mechanics and Maritime Sciences, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
Risling M; Experimental Traumatology Unit, Department of Neuroscience, Karolinska Institute, 171 77 Stockholm, Sweden.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jan 10; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 10.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression*
Brain Injuries, Traumatic/*etiology
Brain Injuries, Traumatic/*metabolism
Cytochrome P-450 CYP1B1/*genetics
Hippocampus/*metabolism
Animals ; Biomarkers ; Brain Injuries, Traumatic/pathology ; Cytochrome P-450 CYP1B1/metabolism ; Disease Models, Animal ; Estrous Cycle ; Female ; Hippocampus/pathology ; Immunohistochemistry ; In Situ Hybridization ; Male ; RNA, Messenger/genetics ; Rats ; Sex Factors

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Skocz do pozycji: 9.

Tytuł:: Hydration and Structural Adaptations of the Human CYP1A1, CYP1A2, and CYP1B1 Active Sites by Molecular Dynamics Simulations.
Autorzy:: Dutkiewicz Z; Department of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland.
Mikstacka R; Department of Inorganic and Analytical Chemistry, Nicolaus Copernicus University, Collegium Medicum, Dr. A. Jurasza 2, 85-089 Bydgoszcz, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 14; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 CYP1A1*/metabolism
Cytochrome P-450 CYP1A2*/metabolism
Humans ; Molecular Dynamics Simulation ; Catalytic Domain ; Ligands ; Cytochrome P-450 CYP1B1/metabolism

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Skocz do pozycji: 10.

Tytuł:: Novel compound heterozygous mutations in CYP1B1 identified in a Chinese family with developmental glaucoma.
Autorzy:: Cai S; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Shenzhen University School of Medicine, Shenzhen, Guangdong 518000, P.R. China.
Zhang D; Xiamen Eye Center, Xiamen University, Xiamen, Fujian 361000, P.R. China.
Jiao X; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20852, USA.
Wang T; Department of Ophthalmology and Optometry, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, Fujian 350004, P.R. China.
Fan M; Department of Ophthalmology and Optometry, School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, Fujian 350004, P.R. China.
Wang Y; Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Shenzhen University School of Medicine, Shenzhen, Guangdong 518000, P.R. China.
Hejtmancik JF; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20852, USA.
Liu X; Xiamen Eye Center, Xiamen University, Xiamen, Fujian 361000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2021 Nov; Vol. 24 (5). Date of Electronic Publication: 2021 Sep 16.
Typ publikacji:: Case Reports; Journal Article
MeSH Terms:: Family*
Genetic Predisposition to Disease*
Heterozygote*
Mutation*
Cytochrome P-450 CYP1B1/*genetics
Glaucoma/*diagnosis
Glaucoma/*genetics
Adolescent ; Alleles ; Amino Acid Substitution ; China ; Cytochrome P-450 CYP1B1/chemistry ; DNA Mutational Analysis ; Genetic Association Studies ; Humans ; Intraocular Pressure ; Male ; Models, Molecular ; Pedigree ; Phenotype ; Structure-Activity Relationship ; Vision Tests ; Visual Acuity

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Skocz do pozycji: 11.

Tytuł:: Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer.
Autorzy:: Presa D; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Khurram SA; Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, 19 Claremont Crescent, Sheffield, S10 2TA, UK.
Zubir AZA; Unit of Oral and Maxillofacial Pathology, School of Clinical Dentistry, 19 Claremont Crescent, Sheffield, S10 2TA, UK.
Smarakan S; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Cooper PA; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Morais GR; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Sadiq M; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Sutherland M; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Loadman PM; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
McCaul J; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.; Regional Maxillofacial Unit, Queen Elizabeth University Hospital, 1345 Govan Road, Glasgow, G51 4TF, UK.
Shnyder SD; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Patterson LH; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK.
Pors K; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, Faculty of Life Sciences, University of Bradford, Bradford, BD7 1DP, West Yorkshire, UK. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Sep 23; Vol. 11 (1), pp. 18930. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*pharmacology
Cytochrome P-450 CYP1A1/*antagonists & inhibitors
Cytochrome P-450 CYP1B1/*antagonists & inhibitors
Cytochrome P450 Family 2/*antagonists & inhibitors
Head and Neck Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Cohort Studies ; Cytochrome P-450 CYP1A1/metabolism ; Cytochrome P-450 CYP1B1/metabolism ; Cytochrome P450 Family 2/metabolism ; Female ; Head and Neck Neoplasms/pathology ; Heterocyclic Compounds, 3-Ring/pharmacology ; Heterocyclic Compounds, 3-Ring/therapeutic use ; Humans ; Indoles/pharmacology ; Indoles/therapeutic use ; Mice ; Prodrugs/pharmacology ; Prodrugs/therapeutic use ; Pyrroles/pharmacology ; Pyrroles/therapeutic use ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 12.

Tytuł:: Cytochrome P450 1B1 Expression Regulates Intracellular Iron Levels and Oxidative Stress in the Retinal Endothelium.
Autorzy:: Song YS; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Zaitoun IS; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Wang S; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Darjatmoko SR; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Sorenson CM; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Sheibani N; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Department of Biomedical Engineering, University of Wisconsin, Madison, WI 53705, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 26; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 26.
Typ publikacji:: Journal Article
MeSH Terms:: Estrogen Receptor alpha*/metabolism
Hepcidins*/genetics
Hepcidins*/metabolism
Animals ; Mice ; Cytochrome P-450 CYP1B1/genetics ; Cytochrome P-450 CYP1B1/metabolism ; Endothelial Cells/metabolism ; Endothelium/metabolism ; Iron/metabolism ; Oxidative Stress/physiology ; Retina/metabolism ; Intracellular Space/metabolism

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Skocz do pozycji: 13.

Tytuł:: 6β-Hydroxytestosterone, a metabolite of testosterone generated by CYP1B1, contributes to vascular changes in angiotensin II-induced hypertension in male mice.
Autorzy:: Pingili AK; Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 71 S. Manassas TSRB, Memphis, TN, 38103, USA.
Jennings BL; Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 71 S. Manassas TSRB, Memphis, TN, 38103, USA.
Mukherjee K; Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 71 S. Manassas TSRB, Memphis, TN, 38103, USA.
Akroush W; Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 71 S. Manassas TSRB, Memphis, TN, 38103, USA.
Gonzalez FJ; Laboratory of Metabolism, National Cancer Institute, Bethesda, MD, 20892, USA.
Malik KU; Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 71 S. Manassas TSRB, Memphis, TN, 38103, USA. .; Pokaż więcej
Źródło:: Biology of sex differences [Biol Sex Differ] 2020 Jan 16; Vol. 11 (1), pp. 4. Date of Electronic Publication: 2020 Jan 16.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Angiotensin II/*metabolism
Aorta, Thoracic/*metabolism
Cytochrome P-450 CYP1B1/*metabolism
Hydroxytestosterones/*metabolism
Hypertension/*metabolism
Angiotensin II/administration & dosage ; Animals ; Aorta, Thoracic/drug effects ; Cytochrome P-450 CYP1B1/genetics ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Oxidative Stress ; Reactive Oxygen Species/metabolism

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Skocz do pozycji: 14.

Tytuł:: Overexpression of MECP2 attenuates cigarette smoke extracts induced lung epithelial cell injury by promoting CYP1B1 methylation.
Autorzy:: Lin J; Neonatology department, the First Affiliated Hospital, Jinan University, China.
Peng J; Department of Respiration, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, China.
Liu G; Neonatology department, the First Affiliated Hospital, Jinan University, China.
Deng L; Department of Respiration, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, China.; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2020; Vol. 45 (3), pp. 177-186.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Methylation*
Gene Expression*
Acute Lung Injury/*chemically induced
Acute Lung Injury/*genetics
Cigarette Smoking/*adverse effects
Cytochrome P-450 CYP1B1/*metabolism
Epithelial Cells/*drug effects
Epithelial Cells/*pathology
Lung/*cytology
Methyl-CpG-Binding Protein 2/*genetics
Methyl-CpG-Binding Protein 2/*metabolism
Plant Extracts/*adverse effects
Nicotiana/*chemistry
Acute Lung Injury/pathology ; Cells, Cultured ; Cytochrome P-450 CYP1B1/genetics ; Humans ; Plant Extracts/isolation & purification

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Skocz do pozycji: 15.

Tytuł:: WY-14643 Regulates CYP1B1 Expression through Peroxisome Proliferator-Activated Receptor α-Mediated Signaling in Human Breast Cancer Cells.
Autorzy:: Hwang YP; Department of Pharmaceutical Engineering, International University of Korea, Jinju 52833, Korea.
Won SS; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Jin SW; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Lee GH; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Pham TH; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Choi JH; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Kang KW; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea.
Jeong HG; College of Pharmacy, Chungnam National University, Daejeon 34134, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Nov 25; Vol. 20 (23). Date of Electronic Publication: 2019 Nov 25.
Typ publikacji:: Journal Article
MeSH Terms:: Breast Neoplasms/*metabolism
Cytochrome P-450 CYP1B1/*genetics
Gene Expression Regulation, Neoplastic/*drug effects
PPAR alpha/*metabolism
Peroxisome Proliferators/*pharmacology
Pyrimidines/*pharmacology
Signal Transduction/*drug effects
Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Cell Proliferation ; Cytochrome P-450 CYP1B1/metabolism ; Female ; Humans ; PPAR alpha/genetics ; Promoter Regions, Genetic ; Response Elements ; Tumor Cells, Cultured

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Skocz do pozycji: 16.

Tytuł:: Left Ventricular Hypertrophy: Roles of Mitochondria CYP1B1 and Melatonergic Pathways in Co-Ordinating Wider Pathophysiology.
Autorzy:: Anderson G; CRC Scotland & London, London E14 6JE, UK. .
Mazzoccoli G; Division of Internal Medicine and Chronobiology Unit, Department of Medical Sciences, Fondazione IRCCS 'Casa Sollievo della Sofferenza', San Giovanni Rotondo, 71013 Foggia, Italy. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Aug 20; Vol. 20 (16). Date of Electronic Publication: 2019 Aug 20.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cytochrome P-450 CYP1B1/*metabolism
Hypertrophy, Left Ventricular/*metabolism
Animals ; Cytochrome P-450 CYP1B1/genetics ; Gastrointestinal Microbiome/physiology ; Humans ; Hypertrophy, Left Ventricular/physiopathology ; Melatonin/metabolism ; Mitochondria/metabolism ; Mitogen-Activated Protein Kinases/metabolism ; Sirtuins/metabolism

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Skocz do pozycji: 17.

Tytuł:: Expanding the phenotypic spectrum of CYP1B1 associated primary congenital glaucoma.
Autorzy:: Gupta V; Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS New Delhi, New Delhi, India.
Panigrahi A; Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS New Delhi, New Delhi, India.
Mahalingam K; Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS New Delhi, New Delhi, India.
Singh A; Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS New Delhi, New Delhi, India.
Somarajan BI; Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS New Delhi, New Delhi, India.
Gupta S; Dr Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS New Delhi, New Delhi, India.; Pokaż więcej
Źródło:: Clinical & experimental ophthalmology [Clin Exp Ophthalmol] 2022 Dec; Vol. 50 (9), pp. 1112-1115. Date of Electronic Publication: 2022 Sep 16.
Typ publikacji:: Letter
MeSH Terms:: Glaucoma*/diagnosis
Glaucoma*/congenital
Humans ; Cytochrome P-450 CYP1B1/genetics ; Mutation ; DNA Mutational Analysis ; Pedigree

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Skocz do pozycji: 18.

Tytuł:: Retinal astrocytes transcriptome reveals Cyp1b1 regulates the expression of genes involved in cell adhesion and migration.
Autorzy:: Falero-Perez J; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
Sorenson CM; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.
Sheibani N; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.; Department of Biomedical Engineering, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Apr 24; Vol. 15 (4), pp. e0231752. Date of Electronic Publication: 2020 Apr 24 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Astrocytes/*physiology
Cell Adhesion/*genetics
Cytochrome P-450 CYP1B1/*metabolism
Gene Expression Regulation/*physiology
Retina/*physiology
Animals ; Cell Movement/genetics ; Cells, Cultured ; Cytochrome P-450 CYP1B1/genetics ; Female ; Male ; Mice ; Mice, Knockout ; Primary Cell Culture ; RNA-Seq ; Retina/cytology

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Skocz do pozycji: 19.

Tytuł:: Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development.
Autorzy:: Maguire M; Endocrinology and Reproductive Physiology Program, University of Wisconsin-Madison, Madison, WI.; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI.
Larsen MC; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI.
Vezina CM; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI.
Quadro L; Department of Food Science and Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey.
Kim YK; Department of Food Science and Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey.
Tanumihardjo SA; Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI.
Jefcoate CR; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Feb 06; Vol. 15 (2), pp. e0228436. Date of Electronic Publication: 2020 Feb 06 (Print Publication: 2020).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Fetal Development*/drug effects
Fetal Development*/genetics
Cholesterol/*biosynthesis
Cytochrome P-450 CYP1B1/*physiology
Liver/*metabolism
Sterol Regulatory Element Binding Proteins/*physiology
Tretinoin/*metabolism
Animals ; Animals, Newborn ; Cytochrome P-450 CYP1B1/genetics ; Embryo, Mammalian ; Female ; Liver/drug effects ; Liver/embryology ; Liver/growth & development ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Pregnancy ; Retinol-Binding Proteins, Plasma/genetics ; Retinol-Binding Proteins, Plasma/metabolism ; Tretinoin/pharmacology

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Skocz do pozycji: 20.

Tytuł:: Inhibition of CYP1B1 ameliorates cardiac hypertrophy induced by uremic toxin.
Autorzy:: Zhang Y; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Wang S; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Huang Y; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Yang K; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Liu Y; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Bi X; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Liu C; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Xiong J; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Zhang B; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Zhao J; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.
Nie L; Department of Nephrology, The Key Laboratory for The Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2020 Jan; Vol. 21 (1), pp. 393-404. Date of Electronic Publication: 2019 Nov 11.
Typ publikacji:: Journal Article
MeSH Terms:: Basic Helix-Loop-Helix Transcription Factors/*genetics
Cardiomegaly/*genetics
Cytochrome P-450 CYP1B1/*genetics
Hydroxyeicosatetraenoic Acids/*genetics
Receptors, Aryl Hydrocarbon/*genetics
Animals ; Arachidonic Acid/genetics ; Arachidonic Acid/metabolism ; Cardiomegaly/chemically induced ; Cardiomegaly/pathology ; Cell Line ; Cytochrome P-450 CYP1B1/antagonists & inhibitors ; Gene Expression Regulation/drug effects ; Humans ; Hydroxyeicosatetraenoic Acids/metabolism ; Indican/toxicity ; Mice ; Rats ; Transcriptional Activation/drug effects

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