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Tytuł :
Edible flowers of Helichrysum italicum: Composition, nutritive value, and bioactivities.
Autorzy :
Primitivo MJ; GeoBioTec, GeoBioSciences, GeoTechnologies and GeoEngineering, Earth Sciences Department, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal. Electronic address: .
Neves M; MARE-IPLeiria, Marine and Environmental Sciences Centre, School of Tourism and Marine Technology, Polytechnic of Leiria, 2520-630 Peniche, Portugal. Electronic address: .
Pires CL; Coimbra Chemistry Center - Institute of Molecular Sciences (CQC-IMS), Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal.
Cruz PF; Coimbra Chemistry Center - Institute of Molecular Sciences (CQC-IMS), Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal. Electronic address: .
Brito C; GeoBioTec, GeoBioSciences, GeoTechnologies and GeoEngineering, Earth Sciences Department, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal; MARE-IPLeiria, Marine and Environmental Sciences Centre, School of Tourism and Marine Technology, Polytechnic of Leiria, 2520-630 Peniche, Portugal. Electronic address: .
Rodrigues AC; CiTechCare, Centre for Innovative Care and Health Technology, School of Health Sciences, Polytechnic of Leiria, 2411-901 Leiria, Portugal. Electronic address: .
de Carvalho CCCR; iBB - Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal; Associate Laboratory i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal. Electronic address: .
Mortimer MM; School of Life Sciences, University of Lincoln, Lincoln LN6 7DL, UK; Quadram Institute, Norwich Research Park, Norwich NR4 7UQ, UK. Electronic address: .
Moreno MJ; Coimbra Chemistry Center - Institute of Molecular Sciences (CQC-IMS), Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal. Electronic address: .
Brito RMM; Coimbra Chemistry Center - Institute of Molecular Sciences (CQC-IMS), Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal. Electronic address: .
Taylor EJ; School of Life Sciences, University of Lincoln, Lincoln LN6 7DL, UK. Electronic address: .
Millson SH; School of Life Sciences, University of Lincoln, Lincoln LN6 7DL, UK. Electronic address: .
Reboredo F; GeoBioTec, GeoBioSciences, GeoTechnologies and GeoEngineering, Earth Sciences Department, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal. Electronic address: .
Jorge Campos M; MARE-IPLeiria, Marine and Environmental Sciences Centre, School of Tourism and Marine Technology, Polytechnic of Leiria, 2520-630 Peniche, Portugal. Electronic address: .
Vaz DC; Coimbra Chemistry Center - Institute of Molecular Sciences (CQC-IMS), Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal; Associate Laboratory LSRE-LCM, Laboratory of Separation and Reaction Engineering and Laboratory of Catalysis and Materials, Polytechnic of Leiria, 2411-901 Leiria, Portugal. Electronic address: .
Ribeiro VS; GeoBioTec, GeoBioSciences, GeoTechnologies and GeoEngineering, Earth Sciences Department, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal; CiTechCare, Centre for Innovative Care and Health Technology, School of Health Sciences, Polytechnic of Leiria, 2411-901 Leiria, Portugal. Electronic address: .
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Źródło :
Food research international (Ottawa, Ont.) [Food Res Int] 2022 Jul; Vol. 157, pp. 111399. Date of Electronic Publication: 2022 May 25.
Typ publikacji :
Journal Article
MeSH Terms :
Helichrysum*/chemistry
Oils, Volatile*/chemistry
Caco-2 Cells ; Flowers/chemistry ; Humans ; Nutritive Value
Czasopismo naukowe
Tytuł :
Guidance for formulating ingredients/products from Chlorella vulgaris and Arthrospira platensis considering carotenoid and chlorophyll bioaccessibility and cellular uptake.
Autorzy :
Nass PP; Department of Food Technology and Science, Federal University of Santa Maria (UFSM), Santa Maria RS 97105-900, Brazil.
do Nascimento TC; Department of Food Technology and Science, Federal University of Santa Maria (UFSM), Santa Maria RS 97105-900, Brazil.
Fernandes AS; Department of Food Technology and Science, Federal University of Santa Maria (UFSM), Santa Maria RS 97105-900, Brazil.
Caetano PA; Department of Food Technology and Science, Federal University of Santa Maria (UFSM), Santa Maria RS 97105-900, Brazil.
de Rosso VV; Department of Bioscience, Federal University of São Paulo (UNIFESP), Santos, São Paulo CEP 11015-020, Brazil.
Jacob-Lopes E; Department of Food Technology and Science, Federal University of Santa Maria (UFSM), Santa Maria RS 97105-900, Brazil.
Zepka LQ; Department of Food Technology and Science, Federal University of Santa Maria (UFSM), Santa Maria RS 97105-900, Brazil. Electronic address: .
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Źródło :
Food research international (Ottawa, Ont.) [Food Res Int] 2022 Jul; Vol. 157, pp. 111469. Date of Electronic Publication: 2022 Jun 06.
Typ publikacji :
Journal Article
MeSH Terms :
Chlorella vulgaris*
Microalgae*
Caco-2 Cells ; Carotenoids ; Chlorophyll ; Digestion ; Humans ; Spirulina ; Tandem Mass Spectrometry
SCR Organism :
Arthrospira platensis
Czasopismo naukowe
Tytuł :
Surfactin effectively improves bioavailability of curcumin by formation of nano-capsulation.
Autorzy :
Shan M; College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China.
Meng F; College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China.
Tang C; College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China.
Zhou L; College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China.
Lu Z; College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, China. Electronic address: .
Lu Y; College of Food Science and Technology, Nanjing University of Finance and Economics, Nanjing 210023, Jiangsu Province, China. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2022 Jul; Vol. 215, pp. 112521. Date of Electronic Publication: 2022 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Curcumin*/chemistry
Nanoparticles*/chemistry
Biological Availability ; Caco-2 Cells ; Digestion ; Drug Carriers/chemistry ; Humans ; Particle Size
Czasopismo naukowe
Tytuł :
Toxicological assessment of a bioactive extract from Triplaris gardneriana Wedd. seeds using alternative models.
Autorzy :
Almeida TS; Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, Brazil.
Lopes Neto JJ; Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, Brazil.
Almeida Filho LCP; Department of Biology, Federal University of Ceara, Fortaleza, Brazil.
Marques DM; Department of Biology, Federal University of Ceara, Fortaleza, Brazil.
Gonçalves de Lima RC; Department of Biological Sciences, Regional University of Cariri, Crato, Brazil.
Nunes RGDS; Department of Biological Sciences, Regional University of Cariri, Crato, Brazil.
Silva JRL; Department of Biological Sciences, Regional University of Cariri, Crato, Brazil.
Kamdem JP; Department of Biological Sciences, Regional University of Cariri, Crato, Brazil.
Almeida LL; Department of Biological Sciences, Regional University of Cariri, Crato, Brazil.
Souza JADCR; Department of Molecular Biology, Federal University of Paraiba, João Pessoa, Brazil.
Farias DF; Department of Molecular Biology, Federal University of Paraiba, João Pessoa, Brazil.
Carvalho AFU; Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza, Brazil.; Department of Biology, Federal University of Ceara, Fortaleza, Brazil.
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Źródło :
Drug and chemical toxicology [Drug Chem Toxicol] 2022 Jul; Vol. 45 (4), pp. 1687-1697. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
MeSH Terms :
Polygonaceae*
Zebrafish*
Animals ; Caco-2 Cells ; Drosophila melanogaster ; Embryo, Nonmammalian ; Ethanol ; Humans ; Larva ; Plant Extracts/toxicity ; Seeds/toxicity
Czasopismo naukowe
Tytuł :
Investigation of the Uptake and Transport of Two Novel Camptothecin Derivatives in Caco-2 Cell Monolayers.
Autorzy :
Wang Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Zhang X; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Zhuang W; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Yu Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Sun X; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Wang H; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
Li F; Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Li Q; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2022 Jun 07; Vol. 27 (12). Date of Electronic Publication: 2022 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Camptothecin*/analogs & derivatives
Camptothecin*/metabolism
Neoplasm Proteins*/metabolism
ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2 ; Biological Transport ; Caco-2 Cells ; Humans
Czasopismo naukowe
Tytuł :
"TPGS surface modified bilosomes as boosting cytotoxic oral delivery systems of curcumin against doxorubicin resistant MCF-7 breast cancer cells".
Autorzy :
Hegazy H; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Sinai University, Ismailia 41636, Egypt.
Amin MM; Department Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Fayad W; Drug Bioassay-Cell Culture Laboratory, Pharmacognosy Department, National Research Centre, Dokki, Giza 12622, Egypt.
Zakaria MY; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Port Said University, Port Said 42526, Egypt. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2022 May 10; Vol. 619, pp. 121717. Date of Electronic Publication: 2022 Apr 01.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*
Breast Neoplasms*/drug therapy
Breast Neoplasms*/pathology
Curcumin*/pharmacology
Caco-2 Cells ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; Female ; Humans ; MCF-7 Cells ; Particle Size ; Polyethylene Glycols/therapeutic use ; Vitamin E ; alpha-Tocopherol
Czasopismo naukowe
Tytuł :
2'-Fucosyllactose promotes Lactobacillus rhamnosus KLDS 8001 to repair LPS-induced damage in Caco-2 cells.
Autorzy :
Li A; Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin, China.
Zhang C; Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin, China.
Chi H; Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin, China.
Han X; Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin, China.
Ma Y; Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin, China.
Zheng J; Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin, China.
Liu C; Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin, China.
Li C; Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin, China.; Heilongjiang Green Food Science Research Institute, Harbin, China.
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Źródło :
Journal of food biochemistry [J Food Biochem] 2022 May; Vol. 46 (5), pp. e14059. Date of Electronic Publication: 2022 Feb 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lactobacillus rhamnosus*
Lipopolysaccharides*
Caco-2 Cells ; Humans ; Intestinal Mucosa/metabolism ; Trisaccharides
Czasopismo naukowe
Tytuł :
Pulse electric field assisted process for extraction of Jiuzao glutelin extract and its physicochemical properties and biological activities investigation.
Autorzy :
Jiang Y; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Xing M; Key Laboratory of Photochemical Conversion and Optoelectronic Material, Technical Institute of Physics and Chemistry, CAS, Beijing 100190, China.
Kang Q; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China.
Sun J; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China. Electronic address: .
Zeng XA; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Gao W; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.
Li H; Key Laboratory of Brewing Molecular Engineering of China Light Industry, Beijing Technology and Business University, Beijing 100048, China.
Gao Y; Key Laboratory of Photochemical Conversion and Optoelectronic Material, Technical Institute of Physics and Chemistry, CAS, Beijing 100190, China.
Li A; Anhui Gujinggongjiu Co. Ltd., Anhui 236000, China.
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Źródło :
Food chemistry [Food Chem] 2022 Jul 30; Vol. 383, pp. 132304. Date of Electronic Publication: 2022 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants*/chemistry
Antioxidants*/pharmacology
Glutens*
Caco-2 Cells ; Electricity ; Humans ; Water
Czasopismo naukowe
Tytuł :
In vitro digestion of milk proteins including intestinal brush border membrane peptidases. Transepithelial transport of resistant casein domains.
Autorzy :
Vivanco-Maroto SM; Instituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM), Madrid, Spain.
Santos-Hernández M; Instituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM), Madrid, Spain.
Sanchón J; Instituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM), Madrid, Spain.
Picariello G; Istituto di Scienze dell'Alimentazione-Consiglio Nazionale delle Ricerche, Avellino, Italy.
Recio I; Instituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM), Madrid, Spain.
Miralles B; Instituto de Investigación en Ciencias de la Alimentación, CIAL (CSIC-UAM), Madrid, Spain. Electronic address: .
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Źródło :
Food research international (Ottawa, Ont.) [Food Res Int] 2022 Jul; Vol. 157, pp. 111238. Date of Electronic Publication: 2022 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Caseins*
Milk Proteins*
Caco-2 Cells ; Digestion ; Humans ; Microvilli ; Peptide Hydrolases
Czasopismo naukowe
Tytuł :
High-throughput drug screening allowed identification of entry inhibitors specifically targeting different routes of SARS-CoV-2 Delta and Omicron/BA.1.
Autorzy :
Kuzikov M; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Schnackenburgallee 114, 22525 Hamburg, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany; Department of Life Sciences and Chemistry, Jacobs University Bremen, 28759 Bremen, Germany.
Woens J; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Zaliani A; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Schnackenburgallee 114, 22525 Hamburg, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany.
Hambach J; Institute of Immunology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Eden T; Institute of Immunology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Fehse B; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, 20246 Hamburg, Germany.
Ellinger B; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Schnackenburgallee 114, 22525 Hamburg, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany. Electronic address: .
Riecken K; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Jul; Vol. 151, pp. 113104. Date of Electronic Publication: 2022 May 16.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/drug therapy
SARS-CoV-2*
Caco-2 Cells ; Drug Evaluation, Preclinical ; Humans ; Spike Glycoprotein, Coronavirus/metabolism
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
SDH, a novel diarylheptane compound, is a potential treatment for inflammatory bowel disease by restoring epithelial barrier function.
Autorzy :
Yang F; Institutes of Biology and Medical Sciences, Soochow University, Suzhou, Jiangsu 215123, China; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Zhu X; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Li L; Institutes of Biology and Medical Sciences, Soochow University, Suzhou, Jiangsu 215123, China. Electronic address: .
Wang Y; Institutes of Biology and Medical Sciences, Soochow University, Suzhou, Jiangsu 215123, China. Electronic address: wyp_.
Xie Q; Institutes of Biology and Medical Sciences, Soochow University, Suzhou, Jiangsu 215123, China. Electronic address: .
Cao Y; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Yu Y; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Zhang M; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Li D; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Li L; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Liu Z; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Zhang B; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Chen Z; School of Basic Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: .
Deng S; Suzhou Pharmavan Co.,Ltd, Suzhou, Jiangsu 215127, China. Electronic address: .
Li Y; Institutes of Biology and Medical Sciences, Soochow University, Suzhou, Jiangsu 215123, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Jul; Vol. 151, pp. 113080. Date of Electronic Publication: 2022 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Colitis*/chemically induced
Colitis*/drug therapy
Colitis*/metabolism
Inflammatory Bowel Diseases*/drug therapy
Inflammatory Bowel Diseases*/metabolism
Animals ; Caco-2 Cells ; Colon/metabolism ; Disease Models, Animal ; Humans ; Intestinal Mucosa/metabolism ; Mice ; Mice, Inbred C57BL ; Tight Junction Proteins/metabolism ; Tight Junctions/metabolism
Czasopismo naukowe
Tytuł :
Bacillus subtilis plays a role in the inhibition of transporter ABCB1 in Caco-2 cells.
Autorzy :
Dai Y; Department of Neurology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Wang M; Department of Neurology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Zhong D; Department of Neurology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Xu X; Department of Neurology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China. Electronic address: .
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Źródło :
Epilepsy research [Epilepsy Res] 2022 Jul; Vol. 183, pp. 106925. Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :
Journal Article
MeSH Terms :
Bacillus subtilis*/genetics
Epilepsy*/genetics
ATP Binding Cassette Transporter, Subfamily B/genetics ; Caco-2 Cells ; Humans ; Membrane Transport Proteins ; RNA, Ribosomal, 16S
Czasopismo naukowe
Tytuł :
Spray-dried indomethacin-loaded polymeric micelles for the improvement of intestinal drug release and permeability.
Autorzy :
Sipos B; Faculty of Pharmacy, Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Eötvös str. 6, Szeged H-6720, Hungary.
Csóka I; Faculty of Pharmacy, Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Eötvös str. 6, Szeged H-6720, Hungary.
Ambrus R; Faculty of Pharmacy, Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Eötvös str. 6, Szeged H-6720, Hungary.
Schelz Z; Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Eötvös str. 6, Szeged H-6720, Hungary.
Zupkó I; Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Eötvös str. 6, Szeged H-6720, Hungary.
Balogh GT; Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Eötvös str. 6, Szeged H-6720, Hungary; Department of Chemical and Environmental Process Engineering, Budapest University of Technology and Economics, Műegyetem quay 3, Budapest H-1111, Hungary.
Katona G; Faculty of Pharmacy, Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Eötvös str. 6, Szeged H-6720, Hungary. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2022 Jul 01; Vol. 174, pp. 106200. Date of Electronic Publication: 2022 May 01.
Typ publikacji :
Journal Article
MeSH Terms :
Indomethacin*/chemistry
Micelles*
Animals ; Caco-2 Cells ; Drug Liberation ; Humans ; Particle Size ; Permeability ; Polymers ; Powders ; Solubility ; Swine
Czasopismo naukowe
Tytuł :
Targeting the interplay between MMP-2, CA II and VEGFR-2 via new sulfonamide-tethered isomeric triazole hybrids; Microwave-assisted synthesis, computational studies and evaluation.
Autorzy :
Reda Aouad M; Department of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia. Electronic address: .
Almehmadi MA; Deanship of Preparatory Year, Prince Sattam Bin Abdulaziz University, Al-Kharj 16273 16278, Saudi Arabia.
Faleh Albelwi F; Department of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia.
Teleb M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt. Electronic address: .
Tageldin GN; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.
Abu-Serie MM; Medical Biotechnology Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Egypt.
Hagar M; Chemistry Department, Faculty of Science, Alexandria University, Alexandria 21321, Egypt.
Rezki N; Department of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia.
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2022 Jul; Vol. 124, pp. 105816. Date of Electronic Publication: 2022 Apr 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents*/chemistry
Vascular Endothelial Growth Factor Receptor-2*
Caco-2 Cells ; Cell Line, Tumor ; Cell Proliferation ; Drug Screening Assays, Antitumor ; Humans ; Ligands ; Matrix Metalloproteinase 2 ; Microwaves ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship ; Sulfonamides/pharmacology ; Triazoles/chemistry
Czasopismo naukowe
Tytuł :
Deoxycholic acid-chitosan coated liposomes combined with in situ colonic gel enhances renal fibrosis therapy of emodin.
Autorzy :
Xu Z; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China.
Hou Y; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China.
Sun J; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China.
Zhu L; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China.
Zhang Q; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China.
Yao W; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China.
Fan X; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China.
Zhang K; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China.
Piao JG; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China.
Wei Y; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 311402, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2022 Jul; Vol. 101, pp. 154110. Date of Electronic Publication: 2022 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
Chitosan*
Emodin*/pharmacology
Kidney Diseases*/drug therapy
Rheum*
Ureteral Obstruction*/drug therapy
Animals ; Caco-2 Cells ; DNA, Ribosomal ; Deoxycholic Acid ; Dysbiosis/drug therapy ; Female ; Fibrosis ; Humans ; Immunoglobulin E ; Liposomes ; Male ; Rats
Czasopismo naukowe
Tytuł :
Development and optimization of a high-throughput screening assay for in vitro anti-SARS-CoV-2 activity: Evaluation of 5676 Phase 1 Passed Structures.
Autorzy :
Chiu W; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Verschueren L; Janssen Pharmaceutica NV, Beerse, Belgium.
Van den Eynde C; Janssen Pharmaceutica NV, Beerse, Belgium.
Buyck C; Janssen Pharmaceutica NV, Beerse, Belgium.
De Meyer S; Janssen Pharmaceutica NV, Beerse, Belgium.
Jochmans D; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Bojkova D; Institute of Medical Virology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Ciesek S; Institute of Medical Virology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
Cinatl J; Institute of Medical Virology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.
De Jonghe S; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Leyssen P; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Neyts J; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Van Loock M; Janssen Pharmaceutica NV, Beerse, Belgium.
Van Damme E; Janssen Pharmaceutica NV, Beerse, Belgium.
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Źródło :
Journal of medical virology [J Med Virol] 2022 Jul; Vol. 94 (7), pp. 3101-3111. Date of Electronic Publication: 2022 Mar 23.
Typ publikacji :
Clinical Trial, Phase I; Journal Article
MeSH Terms :
COVID-19*/drug therapy
SARS-CoV-2*
Animals ; Antiviral Agents/pharmacology ; Caco-2 Cells ; Chlorocebus aethiops ; High-Throughput Screening Assays ; Humans ; Pandemics
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism.
Autorzy :
Tingting W; State Key Laboratory for Zoonotic Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Tianqi F; State Key Laboratory for Zoonotic Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Xinyu W; State Key Laboratory for Zoonotic Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Can Z; State Key Laboratory for Zoonotic Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Xue S; Department of Food Science, College of Food Science and Engineering, Jilin University, Changchun, China.
Xuming D; State Key Laboratory for Zoonotic Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
Jianfeng W; State Key Laboratory for Zoonotic Diseases, Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
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Źródło :
British journal of pharmacology [Br J Pharmacol] 2022 Jul; Vol. 179 (14), pp. 3839-3858. Date of Electronic Publication: 2022 Mar 28.
Typ publikacji :
Journal Article
MeSH Terms :
Listeria monocytogenes*
Listeriosis*/drug therapy
Listeriosis*/microbiology
Animals ; Bacterial Toxins ; Biflavonoids ; Caco-2 Cells ; Disease Models, Animal ; Heat-Shock Proteins ; Hemolysin Proteins/pharmacology ; Hemolysin Proteins/therapeutic use ; Humans ; Mice ; Molecular Docking Simulation ; Virulence
Czasopismo naukowe
Tytuł :
(±)-Involucrasins A and B, two pairs of flavanone enantiomers from Shuteria involucrata and their inhibitory effects on the proliferation of various cancer cell lines.
Autorzy :
Liu L; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Li XH; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Ma XX; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Tan WH; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Ma WZ; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Shen YF; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Khan A; Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
Zhou ZH; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Yang ZY; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
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Źródło :
Journal of Asian natural products research [J Asian Nat Prod Res] 2022 Jul; Vol. 24 (7), pp. 641-647. Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article
MeSH Terms :
Flavanones*/chemistry
Flavanones*/pharmacology
Neoplasms*
Caco-2 Cells ; Cell Line, Tumor ; Cell Proliferation ; Humans ; Inhibitory Concentration 50 ; Molecular Structure
Czasopismo naukowe
Tytuł :
Cellular concentrations of plasmalogen species containing a polyunsaturated fatty acid significantly increase under hypoxia in human colorectal cancer, Caco2 cells.
Autorzy :
Tamiya-Koizumi K; Department of Pathobiology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan.
Otoki Y; Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Nakagawa K; Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Kannagi R; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Mizutani N; Department of Pathophysiological Laboratory Science, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Suzuki M; Department of Molecular Oncology, Fujita Health University, Toyoake, Japan.
Kyogashima M; Department of Microbiology and Molecular Cell Biology, Nihon Pharmaceutical University, Saitama, Japan.
Iwaki S; Department of Pathobiology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan.
Aoyama M; Department of Pathobiology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan.
Murate T; College of Life and Health Sciences, Chubu University, Kasugai, Japan.
Kitatani K; Laboratory of Immunopharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan.
Kuga T; Laboratory of Analytics for Biomolecules, Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan.
Mizutani Y; Department of Molecular Oncology, Fujita Health University, Toyoake, Japan.
Tokumura A; Department of Pharmacy, Yasuda Women's University, Hiroshima, 731-0153, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jun 30; Vol. 611, pp. 1-7. Date of Electronic Publication: 2022 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Colorectal Neoplasms*
Plasmalogens*
Caco-2 Cells ; Fatty Acids, Unsaturated/metabolism ; Humans ; Hypoxia ; Phospholipases
Czasopismo naukowe
Tytuł :
Genome-wide siRNA screening reveals several host receptors for the binding of human gut commensal Bifidobacterium bifidum.
Autorzy :
Kainulainen V; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland. .
von Schantz-Fant C; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Kovanen RM; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Potdar S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Laamanen K; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Saarela J; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Satokari R; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland. .
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Źródło :
NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2022 Jun 29; Vol. 8 (1), pp. 50. Date of Electronic Publication: 2022 Jun 29.
Typ publikacji :
Journal Article
MeSH Terms :
Bifidobacterium bifidum*/genetics
Bifidobacterium/genetics ; Bifidobacterium/metabolism ; Caco-2 Cells ; HT29 Cells ; Humans ; Infant ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism
Czasopismo naukowe

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