Temat: "Caco-2 Cells" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Pitfalls in evaluating permeability experiments with Caco-2/MDCK cell monolayers.
Autorzy:: Ebert A; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research (UFZ), Permoserstraße 15, Leipzig 04318, Federal Republic of Germany. Electronic address: .
Dahley C; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research (UFZ), Permoserstraße 15, Leipzig 04318, Federal Republic of Germany.
Goss KU; Department of Analytical Environmental Chemistry, Helmholtz Centre for Environmental Research (UFZ), Permoserstraße 15, Leipzig 04318, Federal Republic of Germany; Institute of Chemistry, University of Halle-Wittenberg, Kurt-Mothes-Straße 2, Halle 06120, Federal Republic of Germany.; Pokaż więcej
Źródło:: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2024 Mar 01; Vol. 194, pp. 106699. Date of Electronic Publication: 2024 Jan 16.
Typ publikacji:: Journal Article
MeSH Terms:: Caco-2 Cells*
Animals ; Dogs ; Humans ; Madin Darby Canine Kidney Cells ; Cell Membrane Permeability ; Diffusion ; Permeability ; Biological Transport

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Tytuł:: Critical Suitability Evaluation of Caco-2 Cells for Gut-on-a-Chip.
Autorzy:: Pan X; School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.; Shandong Institute of Mechanical Design and Research, Jinan 250353, China.
Chen J; School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.; Shandong Institute of Mechanical Design and Research, Jinan 250353, China.
Han J; School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.; Shandong Institute of Mechanical Design and Research, Jinan 250353, China.
Zhang W; School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.; Shandong Institute of Mechanical Design and Research, Jinan 250353, China.
Su W; School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.; Shandong Institute of Mechanical Design and Research, Jinan 250353, China.
Xu Z; School of Medicine & Population Health, University of Sheffield, Sheffield S10 2RX, U.K.
Li X; Department of Minimally Invasive Comprehensive Treatment of Cancer, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China.
Song M; School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.; Shandong Institute of Mechanical Design and Research, Jinan 250353, China.
Song W; Department of Minimally Invasive Comprehensive Treatment of Cancer, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China.
Xie X; State Key Laboratory of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of Display Material and Technology, School of Electronics and Information Technology, Sun Yat-sen University, Guangzhou 510006, China.
Wang L; School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.; Shandong Institute of Mechanical Design and Research, Jinan 250353, China.; Pokaż więcej
Źródło:: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2024 Sep 25; Vol. 16 (38), pp. 51139-51149. Date of Electronic Publication: 2024 Sep 12.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoembryonic Antigen*/metabolism
Lab-On-A-Chip Devices*
Humans ; Caco-2 Cells ; Biosensing Techniques/methods ; Intestinal Mucosa/cytology ; Intestinal Mucosa/metabolism ; Cell Differentiation/drug effects

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Tytuł:: Apoptosis and Oxidative Stress in Human Intestinal Epithelial Caco-2 Cells Caused by Marine Phycotoxin Azaspiracid-2.
Autorzy:: Zhao L; College of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.
Qiu J; College of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.; Key Laboratory of Marine Environment and Ecology, Ocean University of China, Ministry of Education, Qingdao 266100, China.
Zhang J; College of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.
Li A; College of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.; Key Laboratory of Marine Environment and Ecology, Ocean University of China, Ministry of Education, Qingdao 266100, China.
Wang G; College of Environmental Science and Engineering, Ocean University of China, Qingdao 266100, China.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2024 Aug 31; Vol. 16 (9). Date of Electronic Publication: 2024 Aug 31.
Typ publikacji:: Journal Article
MeSH Terms:: Oxidative Stress*/drug effects
Apoptosis*/drug effects
Marine Toxins*/toxicity
Spiro Compounds*/toxicity
Intestinal Mucosa*/drug effects
Intestinal Mucosa*/metabolism
Humans ; Caco-2 Cells ; Reactive Oxygen Species/metabolism ; Cell Survival/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Polyether Toxins ; Furans ; Pyrans

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Skocz do pozycji: 4.

Tytuł:: How do in vitro digestion and cell metabolism affect the biological activity and phenolic profile of grape juice and wine.
Autorzy:: Pintać Šarac D; University of Novi Sad Faculty of Medicine, Novi Sad, Serbia,. Electronic address: .
Tremmel M; University of Regensburg Faculty of Chemistry and Pharmacy, Regensburg, Germany.
Vujetić J; Institute of Food Technology in Novi Sad (FINS), University of Novi Sad, Novi Sad, Serbia.
Torović L; University of Novi Sad Faculty of Medicine, Novi Sad, Serbia.
Orčić D; University of Novi Sad Faculty of Sciences, Novi Sad, Serbia.
Popović L; University of Novi Sad Faculty of Technology, Novi Sad, Serbia.
Mimica-Dukić N; University of Novi Sad Faculty of Sciences, Novi Sad, Serbia.
Lesjak M; University of Novi Sad Faculty of Sciences, Novi Sad, Serbia.; Pokaż więcej
Źródło:: Food chemistry [Food Chem] 2024 Aug 15; Vol. 449, pp. 139228. Date of Electronic Publication: 2024 Apr 04.
Typ publikacji:: Journal Article
MeSH Terms:: Wine*/analysis
Vitis*/chemistry
Vitis*/metabolism
Digestion*
Fruit and Vegetable Juices*/analysis
Phenols*/metabolism
Phenols*/chemistry
Humans ; Caco-2 Cells ; Antioxidants/chemistry ; Antioxidants/metabolism ; Polyphenols/metabolism ; Polyphenols/chemistry ; Models, Biological

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Tytuł:: Deer Skin Collagen Peptides Bound to Calcium: In Vitro Gastrointestinal Simulation of Digestion, Cellular Uptake and Analysis of Antioxidant Activity.
Autorzy:: Du R; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.; Jilin Provincial Engineering Research Center for Efficient Breeding and Product Development of Sika Deer, Changchun 130118, China.
Sun L; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Liu J; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Gao F; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Guo X; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Shi M; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Guo P; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Chen W; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Zong Y; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Geng J; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Zhao Y; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
He Z; College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.; Jilin Provincial Engineering Research Center for Efficient Breeding and Product Development of Sika Deer, Changchun 130118, China.; Pokaż więcej
Źródło:: Nutrients [Nutrients] 2024 Aug 06; Vol. 16 (16). Date of Electronic Publication: 2024 Aug 06.
Typ publikacji:: Journal Article
MeSH Terms:: Deer*
Antioxidants*/pharmacology
Collagen*/metabolism
Calcium*/metabolism
Digestion*
Peptides*/pharmacology
Peptides*/chemistry
Skin*/metabolism
Animals ; Humans ; Caco-2 Cells ; Molecular Docking Simulation ; Biological Availability ; Gastrointestinal Tract/metabolism ; Chelating Agents/pharmacology

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Tytuł:: Increasing the bioavailability of curcumin using a green supercritical fluid technology-assisted approach based on simultaneous starch aerogel formation-curcumin impregnation.
Autorzy:: Alavi F; Department of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE 68588-6205, USA.
Ciftci ON; Department of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE 68588-6205, USA; Department of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, NE 68583-0726, USA. Electronic address: .; Pokaż więcej
Źródło:: Food chemistry [Food Chem] 2024 Oct 15; Vol. 455, pp. 139468. Date of Electronic Publication: 2024 Apr 24.
Typ publikacji:: Journal Article; Evaluation Study
MeSH Terms:: Curcumin*/chemistry
Curcumin*/administration & dosage
Curcumin*/pharmacokinetics
Biological Availability*
Starch*/chemistry
Gels*/chemistry
Humans ; Caco-2 Cells ; Green Chemistry Technology ; Chromatography, Supercritical Fluid/methods ; Drug Compounding

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Tytuł:: Design, Synthesis, and Biological Evaluation of Covalently Mucoadhesive Derivatives as Nonsystemic Intestine-Targeted TGR5 Agonists.
Autorzy:: Zhao S; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Wang L; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Huang X; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.
Xiao Y; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Li M; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.
Huang X; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Chen X; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.
Li S; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.
Xie J; The First Affiliated Hospital of Henan University, Kaifeng 475000, China.
Liu P; Hebi Key Laboratory of Cardiovascular Diseases, Hebi Key Laboratory of Energy Metabolism, People's Hospital of Hebi, Henan University, Kaifeng 475000, China.
Wang YD; State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
Chen WD; Key Laboratory of Receptors-Mediated Gene Regulation, School of Basic Medical Sciences, Henan University, Kaifeng 475000, China.; Key Laboratory of Receptors-Mediated Gene Regulation and Drug Discovery, School of Basic Medical Science, Inner Mongolia Medical University, Hohhot 010110, China.; Pokaż więcej
Źródło:: Journal of medicinal chemistry [J Med Chem] 2024 Oct 10; Vol. 67 (19), pp. 17701-17712. Date of Electronic Publication: 2024 Sep 25.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, G-Protein-Coupled*/agonists
Receptors, G-Protein-Coupled*/metabolism
Drug Design*
Mice, Inbred C57BL*
Hypoglycemic Agents*/pharmacology
Hypoglycemic Agents*/chemical synthesis
Hypoglycemic Agents*/chemistry
Animals ; Humans ; Caco-2 Cells ; Mice ; Rats ; Male ; Structure-Activity Relationship ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/drug effects ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Rats, Sprague-Dawley

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Tytuł:: Copper nanoparticles biosynthesis by Priestia megaterium and its application as antibacterial and antitumor agents.
Autorzy:: Mohamed SH; Department of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt.
Othman BA; Department of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt.
Abd-Elhalim BT; Department of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt. .
Seada MNA; Department of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Oct 09; Vol. 14 (1), pp. 23615. Date of Electronic Publication: 2024 Oct 09.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Bacterial Agents*/pharmacology
Anti-Bacterial Agents*/biosynthesis
Anti-Bacterial Agents*/chemistry
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/chemistry
Metal Nanoparticles*/chemistry
Copper*/chemistry
Copper*/pharmacology
Humans ; Vero Cells ; Chlorocebus aethiops ; Animals ; Caco-2 Cells ; Actinobacteria/metabolism ; Actinobacteria/genetics ; Microbial Sensitivity Tests

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Tytuł:: In Situ Functionalization of Polar Polythiophene-Based Organic Electrochemical Transistor to Interface In Vitro Models.
Autorzy:: Buchmann S; Division of Nanobiotechnology, Department of Protein Science, SciLifeLab, KTH Royal Institute of Technology, Stockholm 177 65, Sweden.; AIMES─Center for the Advancement of Integrated Medical and Engineering Sciences at Karolinska Institutet and KTH Royal Institute of Technology, Stockholm 171 65, Sweden.; Department of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
Stoop P; Division of Nanobiotechnology, Department of Protein Science, SciLifeLab, KTH Royal Institute of Technology, Stockholm 177 65, Sweden.; AIMES─Center for the Advancement of Integrated Medical and Engineering Sciences at Karolinska Institutet and KTH Royal Institute of Technology, Stockholm 171 65, Sweden.; Department of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
Roekevisch K; Division of Nanobiotechnology, Department of Protein Science, SciLifeLab, KTH Royal Institute of Technology, Stockholm 177 65, Sweden.; AIMES─Center for the Advancement of Integrated Medical and Engineering Sciences at Karolinska Institutet and KTH Royal Institute of Technology, Stockholm 171 65, Sweden.; Department of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
Jain S; Division of Nanobiotechnology, Department of Protein Science, SciLifeLab, KTH Royal Institute of Technology, Stockholm 177 65, Sweden.; Division of Micro and Nano Systems, Department of Intelligent Systems, KTH Royal Institute of Technology, Stockholm 100 44, Sweden.
Kroon R; Department of Science and Technology, Laboratory of Organic Electronics, Linköping University, Norrköping 602 21, Sweden.
Müller C; Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg 412 96, Sweden.
Hamedi MM; Division of Fibre Technology, Department of Fibre and Polymer Technology, KTH Royal Institute of Technology, Stockholm 100 44, Sweden.; Digital Futures, Stockholm 100 44, Sweden.
Zeglio E; AIMES─Center for the Advancement of Integrated Medical and Engineering Sciences at Karolinska Institutet and KTH Royal Institute of Technology, Stockholm 171 65, Sweden.; Department of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.; Digital Futures, Stockholm 100 44, Sweden.; Wallenberg Initiative Materials Science for Sustainability, Department of Materials and Environmental Chemistry, Stockholm University, Stockholm 106 91, Sweden.
Herland A; Division of Nanobiotechnology, Department of Protein Science, SciLifeLab, KTH Royal Institute of Technology, Stockholm 177 65, Sweden.; AIMES─Center for the Advancement of Integrated Medical and Engineering Sciences at Karolinska Institutet and KTH Royal Institute of Technology, Stockholm 171 65, Sweden.; Department of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.; Pokaż więcej
Źródło:: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2024 Oct 09; Vol. 16 (40), pp. 54292-54303. Date of Electronic Publication: 2024 Sep 27.
Typ publikacji:: Journal Article
MeSH Terms:: Thiophenes*/chemistry
Polymers*/chemistry
Transistors, Electronic*
Humans ; Electrochemical Techniques ; Caco-2 Cells ; Polystyrenes/chemistry

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Tytuł:: Comparative genomic analysis of pathogenic factors of Listeria spp. using whole-genome sequencing.
Autorzy:: Qi Y; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Cao Q; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Zhao X; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Tian C; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Li T; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Shi W; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Wei H; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Song C; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Xue H; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China.
Gou H; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, 730070, China. .; Pokaż więcej
Źródło:: BMC genomics [BMC Genomics] 2024 Oct 07; Vol. 25 (1), pp. 935. Date of Electronic Publication: 2024 Oct 07.
Typ publikacji:: Journal Article; Comparative Study
MeSH Terms:: Listeria*/genetics
Listeria*/pathogenicity
Whole Genome Sequencing*
Genome, Bacterial*
Virulence Factors*/genetics
Animals ; Mice ; Humans ; Caco-2 Cells ; Genomics/methods ; RAW 264.7 Cells ; Bacterial Adhesion/genetics ; Virulence/genetics ; Listeriosis/microbiology ; Listeriosis/veterinary

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Tytuł:: Phenotypic and genomic comparison of three human outbreak and one cattle-associated Shiga toxin-producing Escherichia coli O157:H7.
Autorzy:: Peroutka-Bigus N; Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA.; Oak Ridge Institute for Science and Education, Agricultural Research Service Participation Program, Oak Ridge, Tennessee, USA.
Nielsen DW; Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA.; Oak Ridge Institute for Science and Education, Agricultural Research Service Participation Program, Oak Ridge, Tennessee, USA.
Trachsel J; Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA.
Mou KT; Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA.; Oak Ridge Institute for Science and Education, Agricultural Research Service Participation Program, Oak Ridge, Tennessee, USA.
Sharma VK; Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA.
Kudva IT; Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA.
Loving CL; Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa, USA.; Pokaż więcej
Źródło:: Microbiology spectrum [Microbiol Spectr] 2024 Oct 03; Vol. 12 (10), pp. e0414023. Date of Electronic Publication: 2024 Sep 10.
Typ publikacji:: Journal Article; Comparative Study
MeSH Terms:: Escherichia coli Infections*/veterinary
Escherichia coli Infections*/microbiology
Escherichia coli Infections*/epidemiology
Escherichia coli O157*/genetics
Escherichia coli O157*/pathogenicity
Escherichia coli O157*/isolation & purification
Escherichia coli O157*/classification
Disease Outbreaks*
Feces*/microbiology
Phenotype*
Cattle ; Animals ; Humans ; Caco-2 Cells ; Cattle Diseases/microbiology ; Cattle Diseases/epidemiology ; Virulence/genetics ; Biofilms/growth & development ; Virulence Factors/genetics ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Genotype ; Genome, Bacterial ; Genomics

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Tytuł:: Expression of the locus of enterocyte effacement genes during the invasion process of the atypical enteropathogenic Escherichia coli 1711-4 strain of serotype O51:H40.
Autorzy:: Romão FT; Disciplina de Microbiologia, Departamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.; Department of Microbiology, UT Southwestern Medical Center, Dallas, Texas, USA.; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
Santos ACM; Disciplina de Microbiologia, Departamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Puño-Sarmiento JJ; Disciplina de Microbiologia, Departamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Sperandio V; Department of Microbiology, UT Southwestern Medical Center, Dallas, Texas, USA.; Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas, USA.
Hernandes RT; Departamento de Ciências Químicas e Biológicas, Instituto de Biociências, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
Gomes TAT; Disciplina de Microbiologia, Departamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.; Pokaż więcej
Źródło:: Microbiology spectrum [Microbiol Spectr] 2024 Oct 03; Vol. 12 (10), pp. e0030424. Date of Electronic Publication: 2024 Aug 27.
Typ publikacji:: Journal Article
MeSH Terms:: Enteropathogenic Escherichia coli*/genetics
Enteropathogenic Escherichia coli*/pathogenicity
Enteropathogenic Escherichia coli*/metabolism
Escherichia coli Proteins*/genetics
Escherichia coli Proteins*/metabolism
Enterocytes*/microbiology
Escherichia coli Infections*/microbiology
Serogroup*
Flagella*/genetics
Flagella*/metabolism
Humans ; Caco-2 Cells ; Virulence/genetics ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Gene Expression Regulation, Bacterial ; Bacterial Adhesion/genetics ; Animals ; Brazil ; Virulence Factors/genetics ; Virulence Factors/metabolism ; Operon/genetics ; Rats

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Tytuł:: Mind the Particle Rigidity: Blooms the Bioavailability via Rapidly Crossing the Mucus Layer and Alters the Intracellular Fate of Curcumin.
Autorzy:: Yuan D; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technology Research Center, Guangzhou 510640, China.
Niu Z; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technology Research Center, Guangzhou 510640, China.
Zheng W; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technology Research Center, Guangzhou 510640, China.
Zhao Q; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technology Research Center, Guangzhou 510640, China.
Zhou F; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technology Research Center, Guangzhou 510640, China.
Zhao M; School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.; Guangdong Food Green Processing and Nutrition Regulation Technology Research Center, Guangzhou 510640, China.; Chaozhou Branch of Chemistry and Chemical Engineering Guangdong Laboratory, Chaozhou 521000, China.; Pokaż więcej
Źródło:: ACS nano [ACS Nano] 2024 Oct 01; Vol. 18 (39), pp. 27026-27041. Date of Electronic Publication: 2024 Sep 19.
Typ publikacji:: Journal Article
MeSH Terms:: Curcumin*/chemistry
Curcumin*/pharmacokinetics
Curcumin*/pharmacology
Curcumin*/metabolism
Biological Availability*
Mucus*/metabolism
Mucus*/chemistry
Animals ; Humans ; Nanoparticles/chemistry ; Nanoparticles/metabolism ; Drug Carriers/chemistry ; Caco-2 Cells ; Particle Size ; Endocytosis ; Rats, Sprague-Dawley ; Administration, Oral ; Peptides/chemistry ; Peptides/metabolism ; Mice ; Male

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Tytuł:: Glucoraphanin and sulforaphane mitigate TNFα-induced Caco-2 monolayers permeabilization and inflammation.
Autorzy:: Zhu W; Department of Nutrition, University of California, Davis, CA, USA.
Cremonini E; Department of Nutrition, University of California, Davis, CA, USA.
Mastaloudis A; Brassica Protection Products LLC, Baltimore, MD, USA.
Oteiza PI; Department of Nutrition, University of California, Davis, CA, USA; Department of Environmental Toxicology, University of California, Davis, CA, USA. Electronic address: .; Pokaż więcej
Źródło:: Redox biology [Redox Biol] 2024 Oct; Vol. 76, pp. 103359. Date of Electronic Publication: 2024 Sep 17.
Typ publikacji:: Journal Article
MeSH Terms:: Sulfoxides*/pharmacology
Isothiocyanates*/pharmacology
Tumor Necrosis Factor-alpha*/metabolism
Oximes*/pharmacology
Imidoesters*/pharmacology
Imidoesters*/metabolism
Glucosinolates*/pharmacology
Inflammation*/metabolism
Inflammation*/drug therapy
Humans ; Caco-2 Cells ; Signal Transduction/drug effects ; Tight Junctions/metabolism ; Tight Junctions/drug effects ; Permeability/drug effects ; Cell Membrane Permeability/drug effects ; Oxidation-Reduction/drug effects ; NADPH Oxidases/metabolism ; NADPH Oxidases/genetics ; NF-kappa B/metabolism

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Tytuł:: Sulfated Chinese yam polysaccharide exert anti-inflammatory potential via MAPK/NF-κB signaling pathways in a co-culture system and LPS-induced acute inflammatory mice model.
Autorzy:: Chen X; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, China.
Wu S; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, China.
Tao X; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, China.
He F; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, China.
Shen M; State Key Laboratory of Food Science and Resources, Nanchang University, Nanchang, China.; Pokaż więcej
Źródło:: Journal of food science [J Food Sci] 2024 Oct; Vol. 89 (10), pp. 6720-6732. Date of Electronic Publication: 2024 Sep 13.
Typ publikacji:: Journal Article
MeSH Terms:: Polysaccharides*/pharmacology
NF-kappa B*/metabolism
Anti-Inflammatory Agents*/pharmacology
Lipopolysaccharides*/adverse effects
Coculture Techniques*
Dioscorea*/chemistry
Inflammation*/drug therapy
Signal Transduction*/drug effects
Disease Models, Animal*
Animals ; Mice ; RAW 264.7 Cells ; Humans ; Caco-2 Cells ; Male ; Cytokines/metabolism ; MAP Kinase Signaling System/drug effects

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Tytuł:: Studies on absorption mechanism and pharmacokinetic properties of albendazole-bile acid conjugate: In vivo and in vitro.
Autorzy:: Guo Z; State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, Qinghai 810001, PR China; Medical College, Qinghai University, Xining, Qinghai 810001, PR China.
Tang S; State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, Qinghai 810001, PR China; Medical College, Qinghai University, Xining, Qinghai 810001, PR China.
Nie K; College of Life Science and Technology, Beijing University of Chemical of Technology, Beijing 100086, PR China.
Liu J; College of Life Science and Technology, Beijing University of Chemical of Technology, Beijing 100086, PR China.
Hu C; State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, Qinghai 810001, PR China. Electronic address: .; Pokaż więcej
Źródło:: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Oct; Vol. 179, pp. 117400. Date of Electronic Publication: 2024 Sep 08.
Typ publikacji:: Journal Article
MeSH Terms:: Albendazole*/pharmacokinetics
Albendazole*/chemistry
Albendazole*/pharmacology
Albendazole*/administration & dosage
Intestinal Absorption*/drug effects
Rats, Sprague-Dawley*
Bile Acids and Salts*/metabolism
Bile Acids and Salts*/chemistry
Caco-2 Cells ; Animals ; Humans ; Male ; Rats ; Biological Availability ; Biological Transport ; Administration, Oral

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Skocz do pozycji: 17.

Tytuł:: A 3D in-vitro biomimicking Caco-2 intestinal permeability model-based assessment of physically modified telmisartan towards an alkalizer-free formulation development.
Autorzy:: Sah SK; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Kolkata, West Bengal 700054, India.
Alam K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Kolkata, West Bengal 700054, India.
Kumari M; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Kolkata, West Bengal 700054, India.
Malootty R; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Kolkata, West Bengal 700054, India.
Nath S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Kolkata, West Bengal 700054, India.
Ravichandiran V; Department of Natural Products, National Institute of Pharmaceutical Education and Research, Kolkata, West Bengal 700054, India.
Roy S; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Kolkata, West Bengal 700054, India. Electronic address: .
Kaity S; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Kolkata, West Bengal 700054, India. Electronic address: .; Pokaż więcej
Źródło:: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Oct; Vol. 203, pp. 114480. Date of Electronic Publication: 2024 Sep 01.
Typ publikacji:: Journal Article
MeSH Terms:: Telmisartan*/administration & dosage
Telmisartan*/pharmacokinetics
Telmisartan*/chemistry
Solubility*
Permeability*
Particle Size*
Humans ; Caco-2 Cells ; Drug Compounding/methods ; Intestinal Absorption/drug effects ; Powders/chemistry ; Hydrogen-Ion Concentration ; Nanoparticles/chemistry ; Chemistry, Pharmaceutical/methods ; Drug Liberation ; Intestinal Barrier Function

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Tytuł:: 6-Shogaol improves sorafenib efficacy in colorectal cancer cells by modulating its cellular accumulation and metabolism.
Autorzy:: Mehanna MG; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address: .
El-Halawany AM; Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr-El-Ainy Street, Cairo 11562, Egypt. Electronic address: .
Al-Abd AM; Pharmacology Department, Medical and Clinical Research Institute, National Research Centre, Dokki, Cairo 12622, Egypt. Electronic address: .
Alqurashi MM; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address: .
Bukhari HA; Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia; King Abdulaziz University Hospital, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address: .
Kazmi I; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address: .
Al-Qahtani SD; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia. Electronic address: .
Bawadood AS; Basic Medical Sciences Department, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia. Electronic address: .
Anwar F; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address: .
Al-Abbasi FA; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address: .; Pokaż więcej
Źródło:: Pathology, research and practice [Pathol Res Pract] 2024 Oct; Vol. 262, pp. 155520. Date of Electronic Publication: 2024 Aug 22.
Typ publikacji:: Journal Article
MeSH Terms:: Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/metabolism
Sorafenib*/pharmacology
Catechols*/pharmacology
Humans ; Antineoplastic Agents/pharmacology ; Drug Synergism ; Apoptosis/drug effects ; Cell Line, Tumor ; Caco-2 Cells ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use

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Tytuł:: The potential of enteroids derived from children and adults to study age-dependent differences in intestinal CYP3A4/5 metabolism.
Autorzy:: Streekstra EJ; Division of Pharmacology and Toxicology, Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands.
Keuper-Navis M; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, the Netherlands.
van den Heuvel JJWM; Division of Pharmacology and Toxicology, Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands.
van den Broek P; Division of Pharmacology and Toxicology, Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands.
Greupink R; Division of Pharmacology and Toxicology, Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands.
Stommel MWJ; Department of Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.
de Boode WP; Department of Pediatrics, Division of Neonatology, Radboud University Medical Center, Amalia Children's Hospital, Nijmegen, the Netherlands.
Botden SMBI; Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, the Netherlands.
Russel FGM; Division of Pharmacology and Toxicology, Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands.
van de Steeg E; Department of Metabolic Health Research, Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands.
de Wildt SN; Division of Pharmacology and Toxicology, Department of Pharmacy, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Intensive Care, Radboud University Medical Center, Nijmegen, the Netherlands; Department of Neonatal and Pediatric Intensive Care, Erasmus MC Sophia Children's Hospital, Rotterdam, the Netherlands. Electronic address: .; Pokaż więcej
Źródło:: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2024 Oct 01; Vol. 201, pp. 106868. Date of Electronic Publication: 2024 Jul 29.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 CYP3A*/metabolism
Cytochrome P-450 CYP3A*/genetics
Midazolam*/pharmacokinetics
Midazolam*/metabolism
Humans ; Caco-2 Cells ; Child ; Child, Preschool ; Adolescent ; Infant ; Adult ; Infant, Newborn ; Intestinal Mucosa/metabolism ; Male ; Organoids/metabolism ; Age Factors ; Female ; Intestines ; RNA, Messenger/metabolism

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Tytuł:: Pectin from steam explosion-treated citrus peel exhibits good emulsion properties and bioavailability-promoting effect in vitro of nobiletin.
Autorzy:: Yang X; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Liu X; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Zhao S; School of Life Science, Shanxi University, Taiyuan 030006, China.
Huo M; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Tian G; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China. Electronic address: .
Sang Y; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China. Electronic address: .; Pokaż więcej
Źródło:: International journal of biological macromolecules [Int J Biol Macromol] 2024 Oct; Vol. 278 (Pt 2), pp. 134758. Date of Electronic Publication: 2024 Aug 14.
Typ publikacji:: Journal Article
MeSH Terms:: Flavones*/chemistry
Flavones*/pharmacology
Flavones*/pharmacokinetics
Biological Availability*
Pectins*/chemistry
Pectins*/pharmacology
Emulsions*/chemistry
Steam*
Citrus*/chemistry
Humans ; Caco-2 Cells

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