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Wyszukujesz frazę ""Cadherin"" wg kryterium: Temat


Tytuł:
Protocadherin Gamma C3 (PCDHGC3) Is Strongly Expressed in Glioblastoma and Its High Expression Is Associated with Longer Progression-Free Survival of Patients.
Autorzy:
Feldheim J; Section Experimental Neurosurgery, Department of Neurosurgery, University Hospital Würzburg, 97080 Würzburg, Germany.; Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, 45147 Essen, Germany.; Division of Clinical Neurooncology, Department of Neurology, University Hospital Essen, 45147 Essen, Germany.
Wend D; Section Experimental Neurosurgery, Department of Neurosurgery, University Hospital Würzburg, 97080 Würzburg, Germany.; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Würzburg, 97080 Würzburg, Germany.
Lauer MJ; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Würzburg, 97080 Würzburg, Germany.; Graduate School of Life Sciences, Julius-Maximilians-University Würzburg, 97074 Würzburg, Germany.
Monoranu CM; Department of Neuropathology, Institute of Pathology, Julius-Maximilians-University Würzburg, 97080 Würzburg, Germany.
Glas M; Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, 45147 Essen, Germany.; Division of Clinical Neurooncology, Department of Neurology, University Hospital Essen, 45147 Essen, Germany.
Kleinschnitz C; Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, 45147 Essen, Germany.; Division of Clinical Neurooncology, Department of Neurology, University Hospital Essen, 45147 Essen, Germany.
Ernestus RI; Section Experimental Neurosurgery, Department of Neurosurgery, University Hospital Würzburg, 97080 Würzburg, Germany.
Braunger BM; Institute of Anatomy and Cell Biology, Julius-Maximilians-University Würzburg, 97070 Würzburg, Germany.
Meybohm P; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Würzburg, 97080 Würzburg, Germany.
Hagemann C; Section Experimental Neurosurgery, Department of Neurosurgery, University Hospital Würzburg, 97080 Würzburg, Germany.
Burek M; Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Würzburg, 97080 Würzburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jul 22; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 22.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Neoplasms*/genetics
Cadherin Related Proteins*/genetics
Glioblastoma*/genetics
Glioma*/genetics
Cadherins/genetics ; Cadherins/metabolism ; Humans ; Progression-Free Survival ; Protocadherins ; RNA, Messenger
Czasopismo naukowe
Tytuł:
Template-independent genome editing in the Pcdh15 mouse, a model of human DFNB23 nonsyndromic deafness.
Autorzy:
Liu L; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Zou L; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Li K; School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Hou H; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Hu Q; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Liu S; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Li J; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Song C; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Chen J; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Wang S; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Wang Y; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China.
Li C; Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.
Du H; School of Life Sciences, Shandong University, Qingdao, Shandong 266237, China.
Li JL; Chinese Institute for Brain Research, Beijing 102206, China; Academy for Advanced Interdisciplinary Studies (AAIS), Peking University, Beijing 100871, China.
Chen F; Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.
Xu Z; School of Life Sciences, Shandong University, Qingdao, Shandong 266237, China.
Sun W; Chinese Institute for Brain Research, Beijing 102206, China; School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China.
Sun Q; School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Xiong W; School of Life Sciences, Tsinghua University, Beijing 100084, China; IDG/McGovern Institute for Brain Research at Tsinghua University, Tsinghua University, Beijing 100084, China. Electronic address: wei_.
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Źródło:
Cell reports [Cell Rep] 2022 Jul 12; Vol. 40 (2), pp. 111061.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherin Related Proteins*/genetics
Hearing Loss, Sensorineural*/genetics
Hearing Loss, Sensorineural*/pathology
Protein Precursors*/genetics
Animals ; CRISPR-Cas Systems ; Disease Models, Animal ; Gene Editing ; Humans ; Mechanotransduction, Cellular ; Mice
SCR Disease Name:
Deafness, Autosomal Recessive 23; Nonsyndromic Deafness
Czasopismo naukowe
Tytuł:
Clinical Phenotypes of CDHR1 -Associated Retinal Dystrophies.
Autorzy:
Malechka VV; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Cukras CA; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Chew EY; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Sergeev YV; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Blain D; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Jeffrey BG; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Ullah E; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Hufnagel RB; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Brooks BP; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Huryn LA; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Zein WM; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
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Źródło:
Genes [Genes (Basel)] 2022 May 22; Vol. 13 (5). Date of Electronic Publication: 2022 May 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherin Related Proteins*/genetics
Cone-Rod Dystrophies*/genetics
Nerve Tissue Proteins*/genetics
Retinal Dystrophies*/genetics
Cadherins/genetics ; Electroretinography ; Humans ; Mutation ; Phenotype
Czasopismo naukowe
Tytuł:
Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography.
Autorzy:
Elferich J; Vollum Institute, Oregon Health and Science University, Portland, United States.; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, United States.; Howard Hughes Medical Institute, Portland, United States.
Clark S; Vollum Institute, Oregon Health and Science University, Portland, United States.
Ge J; Vollum Institute, Oregon Health and Science University, Portland, United States.
Goehring A; Vollum Institute, Oregon Health and Science University, Portland, United States.; Howard Hughes Medical Institute, Portland, United States.
Matsui A; Vollum Institute, Oregon Health and Science University, Portland, United States.; Howard Hughes Medical Institute, Portland, United States.
Gouaux E; Vollum Institute, Oregon Health and Science University, Portland, United States.; Howard Hughes Medical Institute, Portland, United States.
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Źródło:
ELife [Elife] 2021 Dec 29; Vol. 10. Date of Electronic Publication: 2021 Dec 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cadherin Related Proteins/*chemistry
Protein Precursors/*chemistry
Stereocilia/*ultrastructure
Animals ; Cadherin Related Proteins/ultrastructure ; Cryoelectron Microscopy ; Mice ; Molecular Conformation ; Molecular Structure ; Protein Precursors/ultrastructure
Czasopismo naukowe
Tytuł:
Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.
Autorzy:
Gray ME; Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio, United States of America.; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, United States of America.
Johnson ZR; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, United States of America.
Modak D; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, United States of America.
Tamilselvan E; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, United States of America.; Biophysics Program, The Ohio State University, Columbus, Ohio, United States of America.
Tyska MJ; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.
Sotomayor M; Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio, United States of America.; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, United States of America.; Biophysics Program, The Ohio State University, Columbus, Ohio, United States of America.
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Źródło:
PLoS biology [PLoS Biol] 2021 Dec 06; Vol. 19 (12), pp. e3001463. Date of Electronic Publication: 2021 Dec 06 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cadherin Related Proteins/*ultrastructure
Microvilli/*pathology
Animals ; Caco-2 Cells ; Cadherin Related Proteins/metabolism ; Cadherins/metabolism ; Carrier Proteins/metabolism ; Cell Adhesion ; Cell Adhesion Molecules/metabolism ; Cell Communication ; Cell Line ; Enterocytes/metabolism ; Enterocytes/physiology ; Epithelial Cells/metabolism ; Humans ; Intestine, Small/pathology ; Intestine, Small/physiology ; Mice ; Microvilli/physiology ; Species Specificity
Czasopismo naukowe
Tytuł:
The Role of Cadherin 12 (CDH12) in the Peritoneal Fluid among Patients with Endometriosis and Endometriosis-Related Infertility.
Autorzy:
Goławski K; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, 02-015 Warsaw, Poland.
Soczewica R; College of Inter-Faculty Individual Studies in Mathematics and Natural Sciences, University of Warsaw, 02-097 Warsaw, Poland.
Kacperczyk-Bartnik J; 2nd Department of Obstetrics and Gynecology, Medical University of Warsaw, 00-315 Warsaw, Poland.; Club 35, Polish Society of Gynecologists and Obstetricians, 53-125 Wrocław, Poland.
Mańka G; Angelius Provita Hospital, 40-611 Katowice, Poland.
Kiecka M; Angelius Provita Hospital, 40-611 Katowice, Poland.
Lipa M; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, 02-015 Warsaw, Poland.; Club 35, Polish Society of Gynecologists and Obstetricians, 53-125 Wrocław, Poland.
Warzecha D; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, 02-015 Warsaw, Poland.
Spaczyński R; Division of Infertility and Reproductive Endocrinology, Department of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, 60-572 Poznan, Poland.
Piekarski P; Division of Infertility and Reproductive Endocrinology, Department of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, 60-572 Poznan, Poland.
Banaszewska B; Division of Infertility and Reproductive Endocrinology, Department of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, 60-572 Poznan, Poland.
Jakimiuk A; Department of Reproductive Health, Insitute of Mother and Child in Warsaw, 01-211 Warsaw, Poland.; Department of Obstetrics and Gynecology, Central Clinical Hospital of the Ministry of Interior, 02-507 Warsaw, Poland.
Issat T; Department of Reproductive Health, Insitute of Mother and Child in Warsaw, 01-211 Warsaw, Poland.; Department of Obstetrics and Gynecology, Central Clinical Hospital of the Ministry of Interior, 02-507 Warsaw, Poland.
Rokita W; Collegium Medicum, Jan Kochanowski University in Kielce, 25-369 Kielce, Poland.; Clinic of Obstetrics and Gynecology, Provincial Combined Hospital in Kielce, 25-736 Kielce, Poland.
Młodawski J; Collegium Medicum, Jan Kochanowski University in Kielce, 25-369 Kielce, Poland.; Clinic of Obstetrics and Gynecology, Provincial Combined Hospital in Kielce, 25-736 Kielce, Poland.
Szubert M; Club 35, Polish Society of Gynecologists and Obstetricians, 53-125 Wrocław, Poland.; Department of Gynecology and Obstetrics, Medical University of Lodz, 90-419 Lodz, Poland.; Department of Surgical Gynecology and Oncology, Medical University of Lodz, 90-419 Lodz, Poland.
Sieroszewski P; Department of Gynecology and Obstetrics, Medical University of Lodz, 90-419 Lodz, Poland.; Department of Fetal Medicine and Gynecology, Medical University of Lodz, 90-419 Lodz, Poland.
Raba G; Clinic of Obstetrics and Gynecology in Przemysl, 37-700 Przemysl, Poland.; Department of Obstetrics and Gynecology, University of Rzeszow, 35-310 Rzeszow, Poland.
Szczupak K; Clinic of Obstetrics and Gynecology in Przemysl, 37-700 Przemysl, Poland.; Department of Obstetrics and Gynecology, University of Rzeszow, 35-310 Rzeszow, Poland.
Kluz T; Department of Gynecology, Gynecology Oncology and Obstetrics, Institute of Medical Sciences, Medical College of Rzeszow University, 35-310 Rzeszow, Poland.
Kluza M; Department of Gynecology, Gynecology Oncology and Obstetrics, Institute of Medical Sciences, Medical College of Rzeszow University, 35-310 Rzeszow, Poland.
Wielgoś M; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, 02-015 Warsaw, Poland.
Koc-Żórawska E; 2nd Department of Nephrology and Hypertension with Dialysis Unit, Medical University of Bialystok, 15-089 Bialystok, Poland.
Żórawski M; Department of Clinical Medicine, Medical University of Bialystok, 15-089 Bialystok, Poland.
Laudański P; 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, 02-015 Warsaw, Poland.; OVIklinika Infertility Center, 01-377 Warsaw, Poland.
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Źródło:
International journal of environmental research and public health [Int J Environ Res Public Health] 2022 Sep 14; Vol. 19 (18). Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article; Multicenter Study
MeSH Terms:
Endometriosis*/complications
Infertility, Female*/etiology
Cadherin Related Proteins/*metabolism
Ascitic Fluid/pathology ; Cadherins ; Cross-Sectional Studies ; Female ; Humans
Czasopismo naukowe
Tytuł:
Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.
Autorzy:
Eliasen AU; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Section for Bioinformatics, Technical University of Denmark, Kongens Lyngby, Denmark.
Pedersen CET; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Rasmussen MA; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Food Science, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.
Wang N; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Soverini M; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Fritz A; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Section for Bioinformatics, Technical University of Denmark, Kongens Lyngby, Denmark.
Stokholm J; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Chawes BL; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Morin A; Department of Human Genetics, University of Chicago, Chicago, Ill.
Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Copenhagen, Denmark.
Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Copenhagen, Denmark.
Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Copenhagen, Denmark.
Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Copenhagen, Denmark.
Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Mortensen PB; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Aarhus, Denmark; National Center for Register-Based Research (NCRR), Business and Social Sciences, Aarhus University, Aarhus, Denmark; Center for Integrated Register-Based Research (CIRRAU), Aarhus University, Aarhus, Denmark.
Hougaard DM; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Aarhus, Denmark; Department for Congenital Disorders, Statens Serum Institut (SSI), Copenhagen, Denmark; Den Neonatale Screenings Biobank, SSI, Copenhagen, Denmark.
Bybjerg-Grauholm J; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Aarhus, Denmark; Den Neonatale Screenings Biobank, SSI, Copenhagen, Denmark.
Bækvad-Hansen M; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Aarhus, Denmark; Department for Congenital Disorders, Statens Serum Institut (SSI), Copenhagen, Denmark.
Mors O; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Aarhus, Denmark; Psychosis Research Unit, Aarhus University Hospital-Psychiatry, Risskov, Denmark.
Nordentoft M; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Aarhus, Denmark; Mental Health Center Copenhagen, Capital Region of Denmark, Copenhagen University Hospital, Copenhagen, Denmark.
Børglum AD; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Aarhus, Denmark; Center for Integrative Sequencing, Department of Biomedicine and iSEQ, Aarhus University, Aarhus, Denmark.
Werge T; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Aarhus, Denmark; Institute of Biological Psychiatry, Copenhagen Mental Health Services, Copenhagen, Denmark; Institute of Clinical Medicine and GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
Agerbo E; iPSYCH, The Lundbeck Foundation Initiative for Integrated Psychiatric Research, Aarhus, Denmark; National Center for Register-Based Research (NCRR), Business and Social Sciences, Aarhus University, Aarhus, Denmark; Center for Integrated Register-Based Research (CIRRAU), Aarhus University, Aarhus, Denmark.
Söderhall C; Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Wash.
Altman MC; Department of Medicine, University of Washington, Seattle, Sweden.
Thysen AH; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
McKennan CG; Department of Statistics, University of Pittsburgh, Pittsburgh, Pa.
Brix S; Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
Gern JE; Department of Pediatrics, University of Wisconsin, Madison, Wis.
Ober C; Department of Human Genetics, University of Chicago, Chicago, Ill.
Ahluwalia TS; Steno Diabetes Center Copenhagen, Gentofte, Denmark; Bioinformatics Center, University of Copenhagen, Copenhagen, Denmark.
Bisgaard H; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Pedersen AG; Department of Health Technology, Section for Bioinformatics, Technical University of Denmark, Kongens Lyngby, Denmark.
Bønnelykke K; Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. Electronic address: .
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Źródło:
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2022 Sep; Vol. 150 (3), pp. 622-630. Date of Electronic Publication: 2022 Apr 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Asthma*/genetics
Genome-Wide Association Study*
Cadherin Related Proteins ; Cadherins/genetics ; Genetic Predisposition to Disease ; Humans ; Interleukin-17/genetics ; Membrane Proteins/genetics ; Neoplasm Proteins/genetics ; Polymorphism, Single Nucleotide ; Pore Forming Cytotoxic Proteins
Czasopismo naukowe
Tytuł:
Panel-based next-generation sequencing identifies novel mutations in Bulgarian patients with inherited retinal dystrophies.
Autorzy:
Kamenarova K; Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria.; Laboratory of Genomic Diagnostics, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria.
Mihova K; Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria.; Laboratory of Genomic Diagnostics, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria.
Veleva N; Department of Ophthalmology, University Hospital 'Alexandrovska', Medical University of Sofia, Sofia, Bulgaria.
Mermeklieva E; Clinic of Ophthalmology, University Hospital 'Lozenetz', Medical Faculty, Sofia University 'St. Kliment Ohridski', Sofia, Bulgaria.
Mihaylova B; Clinic 'Vision', Sofia, Bulgaria.
Dimitrova G; Department of Ophthalmology, University Hospital 'Alexandrovska', Medical University of Sofia, Sofia, Bulgaria.
Oscar A; Department of Ophthalmology, University Hospital 'Alexandrovska', Medical University of Sofia, Sofia, Bulgaria.
Shandurkov I; Clinic 'Vision', Sofia, Bulgaria.
Cherninkova S; Department of Neurology, University hospital 'Alexandrovska', Medical University of Sofia, Sofia, Bulgaria.
Kaneva R; Molecular Medicine Center, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria.; Laboratory of Genomic Diagnostics, Department of Medical Chemistry and Biochemistry, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria.
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Źródło:
Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2022 Aug; Vol. 10 (8), pp. e1997. Date of Electronic Publication: 2022 Jun 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Copy Number Variations*
Retinal Dystrophies*/diagnosis
Retinal Dystrophies*/genetics
ATP-Binding Cassette Transporters/genetics ; Bestrophins/genetics ; Bulgaria ; Cadherin Related Proteins ; Cadherins/genetics ; Eye Proteins/genetics ; High-Throughput Nucleotide Sequencing ; Humans ; Mutation ; Nerve Tissue Proteins/genetics ; Pedigree
Czasopismo naukowe
Tytuł:
Protocadherin 15 suppresses oligodendrocyte progenitor cell proliferation and promotes motility through distinct signalling pathways.
Autorzy:
Zhen Y; Menzies Institute for Medical Research, University of Tasmania, Liverpool St, Hobart, 7000, Australia.
Cullen CL; Menzies Institute for Medical Research, University of Tasmania, Liverpool St, Hobart, 7000, Australia.
Ricci R; Menzies Institute for Medical Research, University of Tasmania, Liverpool St, Hobart, 7000, Australia.
Summers BS; Menzies Institute for Medical Research, University of Tasmania, Liverpool St, Hobart, 7000, Australia.
Rehman S; Department of Otorhinolaryngology Head and Neck Surgery, School of Medicine, University of Maryland, Baltimore, MD, 21201, USA.
Ahmed ZM; Department of Otorhinolaryngology Head and Neck Surgery, School of Medicine, University of Maryland, Baltimore, MD, 21201, USA.
Foster AY; Jungers Center for Neurosciences Research, Department of Neurology, Oregon Health & Science University, Portland, OR, 97239, USA.
Emery B; Jungers Center for Neurosciences Research, Department of Neurology, Oregon Health & Science University, Portland, OR, 97239, USA.
Gasperini R; Menzies Institute for Medical Research, University of Tasmania, Liverpool St, Hobart, 7000, Australia.; School of Medicine, University of Tasmania, Liverpool St, Hobart, 7000, Australia.
Young KM; Menzies Institute for Medical Research, University of Tasmania, Liverpool St, Hobart, 7000, Australia. .
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Źródło:
Communications biology [Commun Biol] 2022 May 30; Vol. 5 (1), pp. 511. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Glioma*/genetics
Glioma*/metabolism
Oligodendrocyte Precursor Cells*
Cadherin Related Proteins ; Cell Proliferation ; Humans ; Oligodendroglia ; Protocadherins
Czasopismo naukowe
Tytuł:
Role of CDH23 as a prognostic biomarker and its relationship with immune infiltration in acute myeloid leukemia.
Autorzy:
Yang J; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
Lu F; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
Ma G; Hematology and Oncology Unit, Department of Geriatrics, Qilu Hospital of Shandong University, Jinan, China.
Pang Y; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
Zhao Y; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
Sun T; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
Ma D; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
Ye J; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
Ji C; Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China. .
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Źródło:
BMC cancer [BMC Cancer] 2022 May 21; Vol. 22 (1), pp. 568. Date of Electronic Publication: 2022 May 21.
Typ publikacji:
Journal Article
MeSH Terms:
Leukemia, Myeloid, Acute*/pathology
Biomarkers ; Cadherin Related Proteins ; Cadherins/genetics ; Gene Expression Profiling ; Humans ; Prognosis
Czasopismo naukowe
Tytuł:
Variants in CDH23 cause a broad spectrum of hearing loss: from non-syndromic to syndromic hearing loss as well as from congenital to age-related hearing loss.
Autorzy:
Usami SI; Department of Hearing Implant Sciences, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan. .
Isaka Y; Department of Hearing Implant Sciences, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Miyagawa M; Department of Hearing Implant Sciences, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Nishio SY; Department of Hearing Implant Sciences, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
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Źródło:
Human genetics [Hum Genet] 2022 Apr; Vol. 141 (3-4), pp. 903-914. Date of Electronic Publication: 2022 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Hearing Loss, Sensorineural*/genetics
Usher Syndromes*/genetics
Cadherin Related Proteins/genetics ; Cadherins/genetics ; Deafness ; Humans ; Mutation
SCR Disease Name:
Deafness, Autosomal Recessive 12; Nonsyndromic Deafness
Czasopismo naukowe
Tytuł:
Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.
Autorzy:
Lodge EJ
Xekouki P
Silva TS
Kochi C
Longui CA
Faucz FR
Santambrogio A
Mills JL
Pankratz N
Lane J
Sosnowska D
Hodgson T
Patist AL
Francis-West P
Helmbacher F
Stratakis C
Andoniadou CL
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Źródło:
JCI insight [JCI Insight] 2020 Oct 27; Vol. 5 (23). Date of Electronic Publication: 2020 Oct 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cadherin Related Proteins/*genetics
Cadherins/*genetics
Pituitary Diseases/*genetics
Adolescent ; Animals ; Cadherin Related Proteins/metabolism ; Cadherins/metabolism ; Female ; Humans ; Hypothalamus/growth & development ; Hypothalamus/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mutation ; Pituitary Gland/growth & development ; Pituitary Gland/metabolism ; Young Adult
Czasopismo naukowe
Tytuł:
Mesalazine initiates an anti-oncogenic β-catenin / MUCDHL negative feed-back loop in colon cancer cells by cell-specific mechanisms.
Autorzy:
Bersuder E; Université de Strasbourg, Inserm, IRFAC / UMR-S1113, FHU ARRIMAGE, FMTS, Strasbourg, France.
Terciolo C; Université de Strasbourg, Inserm, IRFAC / UMR-S1113, FHU ARRIMAGE, FMTS, Strasbourg, France.
Lechevrel M; Université de Caen / Basse-Normandie, UFR de Médecine, EA 4652, F-14032 Caen, France.
Martin E; Université de Strasbourg, Inserm, IRFAC / UMR-S1113, FHU ARRIMAGE, FMTS, Strasbourg, France.
Quesnelle C; Université de Caen / Basse-Normandie, UFR de Médecine, EA 4652, F-14032 Caen, France.
Freund JN; Université de Strasbourg, Inserm, IRFAC / UMR-S1113, FHU ARRIMAGE, FMTS, Strasbourg, France.
Reimund JM; Université de Strasbourg, Inserm, IRFAC / UMR-S1113, FHU ARRIMAGE, FMTS, Strasbourg, France; Université de Caen / Basse-Normandie, UFR de Médecine, EA 4652, F-14032 Caen, France; Service Hépato-Gastroentérologie, Hôpitaux Universitaires de Strasbourg, F-67000 Strasbourg, France; Institut Hospitalo-Universitaire de Strasbourg, Hôpitaux Universitaires de Strasbourg, F-67000 Strasbourg, France. Electronic address: .
Gross I; Université de Strasbourg, Inserm, IRFAC / UMR-S1113, FHU ARRIMAGE, FMTS, Strasbourg, France. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Feb; Vol. 146, pp. 112543. Date of Electronic Publication: 2021 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Colonic Neoplasms*/drug therapy
Colonic Neoplasms*/genetics
Colonic Neoplasms*/metabolism
Colorectal Neoplasms*/genetics
Cadherin Related Proteins ; Cadherins/genetics ; Cadherins/metabolism ; Humans ; Mesalamine/pharmacology ; Wnt Signaling Pathway ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł:
The proton ATPase inhibitor bafilomycin A 1 reduces the release of rhinovirus C and cytokines from primary cultures of human nasal epithelial cells.
Autorzy:
Yamaya M; Department of Respiratory Medicine, Tohoku University Graduate School of Medicine, Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan; Department of Advanced Preventive Medicine for Infectious Disease, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan; Virus Research Center, Clinical Research Division, Sendai Medical Center, Sendai 983-8520, Japan. Electronic address: .
Deng X; Department of Advanced Preventive Medicine for Infectious Disease, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan; Department of Kampo and Integrative Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Kikuchi A; Department of Kampo and Integrative Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan; Department of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, 980-8574, Japan.
Sugawara M; Department of Otolaryngology, Tohoku Kosai Hospital, Sendai, 980-0803, Japan.
Saito N; Department of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, 980-8574, Japan.
Kubo T; Japanese Red Cross Nagasaki Genbaku Isahaya Hospital, Isahaya, Nagasaki, 859-0401 Japan.
Momma H; Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Kawase T; Laboratory of Rehabilitative Auditory Science, Tohoku University Graduate School of Biomedical Engineering, Sendai 980-8575, Japan.
Nakagome K; Department of Respiratory Medicine and Allergy Center, Saitama Medical University, Saitama 350-0495, Japan.
Shimotai Y; Department of Infectious Diseases, Yamagata University Faculty of Medicine, Yamagata 990-9585, Japan.
Nishimura H; Virus Research Center, Clinical Research Division, Sendai Medical Center, Sendai 983-8520, Japan.
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Źródło:
Virus research [Virus Res] 2021 Oct 15; Vol. 304, pp. 198548. Date of Electronic Publication: 2021 Aug 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Picornaviridae Infections*
Protons*
Adenosine Triphosphatases/metabolism ; Cadherin Related Proteins ; Cadherins/genetics ; Cadherins/metabolism ; Cells, Cultured ; Cytokines/metabolism ; Enterovirus ; Epithelial Cells ; Humans ; Macrolides ; Membrane Proteins/genetics ; RNA/metabolism ; Rhinovirus ; Virus Replication
SCR Organism:
Rhinovirus C
Czasopismo naukowe
Tytuł:
Markedly reduced myocardial expression of γ-protocadherins and long non-coding RNAs in patients with heart disease.
Autorzy:
Sandstedt J; Department of Clinical Chemistry, Sahlgrenska University Hospital and Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden.
Vukusic K; Department of Clinical Chemistry, Sahlgrenska University Hospital and Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden.
Rekabdar E; Genomics Core Facility, Sahlgrenska Academy, University of Gothenburg, SE-405 30 Gothenburg, Sweden.
Dellgren G; Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, SE-413 45 Gothenburg, Sweden; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden.
Jeppsson A; Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, SE-413 45 Gothenburg, Sweden; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden.
Mattsson Hultén L; Department of Clinical Chemistry, Sahlgrenska University Hospital and Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden.
Rotter Sopasakis V; Department of Clinical Chemistry, Sahlgrenska University Hospital and Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, SE-413 45 Gothenburg, Sweden. Electronic address: .
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Źródło:
International journal of cardiology [Int J Cardiol] 2021 Dec 01; Vol. 344, pp. 149-159. Date of Electronic Publication: 2021 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
Heart Diseases*/genetics
RNA, Long Noncoding*/genetics
Cadherin Related Proteins ; Cadherins ; Humans ; Prospective Studies
Czasopismo naukowe
Tytuł:
The GSDMB rs7216389 SNP is associated with chronic rhinosinusitis in a multi-institutional cohort.
Autorzy:
Zack DE; Department of Otolaryngology, University of Arizona, Tucson, Arizona, USA.
Stern DA; Asthma and Airway Disease Research Center, University of Arizona, Tucson, Arizona, USA.
Willis AL; Department of Otolaryngology, University of Arizona, Tucson, Arizona, USA.
Kim AS; Department of Otolaryngology, University of Arizona, Tucson, Arizona, USA.
Mansfield CJ; Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Reed DR; Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA.
Brooks SG; Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Adappa ND; Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Palmer JN; Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cohen NA; Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA.
Chiu AG; Department of Otolaryngology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Song BH; Department of Otolaryngology, University of Arizona, Tucson, Arizona, USA.
Le CH; Department of Otolaryngology, University of Arizona, Tucson, Arizona, USA.
Chang EH; Department of Otolaryngology, University of Arizona, Tucson, Arizona, USA.
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Źródło:
International forum of allergy & rhinology [Int Forum Allergy Rhinol] 2021 Dec; Vol. 11 (12), pp. 1647-1653. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural
MeSH Terms:
Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide*
Neoplasm Proteins/*genetics
Sinusitis/*genetics
Adult ; Cadherin Related Proteins ; Cadherins/genetics ; Case-Control Studies ; Child ; Chronic Disease ; Genotype ; Humans ; Membrane Proteins/genetics ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Proposed therapy, developed in a Pcdh15 -deficient mouse, for progressive loss of vision in human Usher syndrome.
Autorzy:
Sethna S; Department of Otorhinolaryngology - Head & Neck Surgery, University of Maryland School of Medicine, Baltimore, United States.
Zein WM; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, United States.
Riaz S; Department of Otorhinolaryngology - Head & Neck Surgery, University of Maryland School of Medicine, Baltimore, United States.; National Center of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Giese AP; Department of Otorhinolaryngology - Head & Neck Surgery, University of Maryland School of Medicine, Baltimore, United States.
Schultz JM; Laboratory of Molecular Genetics, National Institute of Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States.
Duncan T; Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, United States.
Hufnagel RB; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, United States.
Brewer CC; Otolaryngology Branch, National Institute of Deafness and Other Communication Disorders, Bethesda, United States.
Griffith AJ; Otolaryngology Branch, National Institute of Deafness and Other Communication Disorders, Bethesda, United States.
Redmond TM; Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, United States.
Riazuddin S; Department of Otorhinolaryngology - Head & Neck Surgery, University of Maryland School of Medicine, Baltimore, United States.
Friedman TB; Laboratory of Molecular Genetics, National Institute of Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States.
Ahmed ZM; Department of Otorhinolaryngology - Head & Neck Surgery, University of Maryland School of Medicine, Baltimore, United States.; Departments of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, United States.; Departments of Molecular Biology and Biochemistry, University of Maryland School of Medicine, Baltimore, United States.
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Źródło:
ELife [Elife] 2021 Nov 09; Vol. 10. Date of Electronic Publication: 2021 Nov 09.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Phenotype*
Cadherins/*genetics
Protein Precursors/*genetics
Usher Syndromes/*therapy
Adolescent ; Adult ; Aged ; Animals ; Cadherin Related Proteins ; Cadherins/metabolism ; Child ; Humans ; Mice ; Middle Aged ; Mutation ; Photoreceptor Cells/pathology ; Protein Precursors/metabolism ; Young Adult
Czasopismo naukowe
Tytuł:
The role of CDHR3 in susceptibility to otitis media.
Autorzy:
Hirsch SD; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.
Elling CL; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.
Bootpetch TC; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.
Scholes MA; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.; Department of Pediatric Otolaryngology, Children's Hospital Colorado (CHCO), 13123 E. 16th Ave, Aurora, CO, 80045, USA.
Hafrén L; Department of Otorhinolaryngology, Head & Neck Surgery, University of Helsinki and Helsinki University Hospital, Tukholmankatu 8A, 00290, Helsinki, Finland.
Streubel SO; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.; Department of Pediatric Otolaryngology, Children's Hospital Colorado (CHCO), 13123 E. 16th Ave, Aurora, CO, 80045, USA.
Pine HS; Department of Otolaryngology, University of Texas Medical Branch (UTMB), 301 8th St, Galveston, TX, 77550, USA.
Wine TM; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.; Department of Pediatric Otolaryngology, Children's Hospital Colorado (CHCO), 13123 E. 16th Ave, Aurora, CO, 80045, USA.
Szeremeta W; Department of Otolaryngology, University of Texas Medical Branch (UTMB), 301 8th St, Galveston, TX, 77550, USA.
Prager JD; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.; Department of Pediatric Otolaryngology, Children's Hospital Colorado (CHCO), 13123 E. 16th Ave, Aurora, CO, 80045, USA.
Einarsdottir E; Folkhälsan Institute of Genetics and Molecular Neurology Research Program, University of Helsinki, PO Box 63, Biomedicum 1, 3rd floor, Haartmaninkatu 8, 00014, Helsinki, Finland.; Department of Biosciences and Nutrition, Karolinska Institute, 141 86, Huddinge, Stockholm, Sweden.; Science for Life Laboratory, Department of Gene Technology, KTH-Royal Institute of Technology, 171 21, Solna, Sweden.
Yousaf A; Bahauddin Zakariya University, Multan, 60000, Punjab, Pakistan.
Baschal EE; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.
Rehman S; Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, University of Maryland, 670 West Baltimore St., Room 7181, Baltimore, MD, 21201, USA.
Bamshad MJ; Department of Genome Sciences, University of Washington, William H. Foege Hall, 3720 15th Ave. NE, Seattle, WA, 98195, USA.
Nickerson DA; Department of Genome Sciences, University of Washington, William H. Foege Hall, 3720 15th Ave. NE, Seattle, WA, 98195, USA.
Riazuddin S; Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, University of Maryland, 670 West Baltimore St., Room 7181, Baltimore, MD, 21201, USA.
Leal SM; Center for Statistical Genetics, Gertrude H. Sergievsky Center, Department of Neurology, Taub Institute for Alzheimer's Disease and the Aging Brain, Columbia University, William Black Building, 650 West 168th St, New York, NY, 10032, USA.
Ahmed ZM; Department of Otorhinolaryngology, Head and Neck Surgery, School of Medicine, University of Maryland, 670 West Baltimore St., Room 7181, Baltimore, MD, 21201, USA.
Yoon PJ; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.; Department of Pediatric Otolaryngology, Children's Hospital Colorado (CHCO), 13123 E. 16th Ave, Aurora, CO, 80045, USA.
Kere J; Folkhälsan Institute of Genetics and Molecular Neurology Research Program, University of Helsinki, PO Box 63, Biomedicum 1, 3rd floor, Haartmaninkatu 8, 00014, Helsinki, Finland.; Department of Biosciences and Nutrition, Karolinska Institute, 141 86, Huddinge, Stockholm, Sweden.
Chan KH; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.; Department of Pediatric Otolaryngology, Children's Hospital Colorado (CHCO), 13123 E. 16th Ave, Aurora, CO, 80045, USA.
Mattila PS; Department of Otorhinolaryngology, Head & Neck Surgery, University of Helsinki and Helsinki University Hospital, Tukholmankatu 8A, 00290, Helsinki, Finland.
Friedman NR; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA.; Department of Pediatric Otolaryngology, Children's Hospital Colorado (CHCO), 13123 E. 16th Ave, Aurora, CO, 80045, USA.
Chonmaitree T; Division of Infectious Diseases, Department of Pediatrics, UTMB, 301 8th St, Galveston, TX, 77550, USA.
Frank DN; Division of Infectious Diseases, Department of Medicine, School of Medicine, CU-AMC, 12700 E. 19th Ave, Aurora, CO, 80045, USA.
Ryan AF; Division of Otolaryngology, Department of Surgery, San Diego School of Medicine and Veterans Affairs Medical Center, University of California, 9500 Gilman Dr, La Jolla, CA, 92093, USA.
Santos-Cortez RLP; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Colorado Anschutz Medical Campus (CU-AMC), 12700 E. 19th Ave, Aurora, CO, 80045, USA. .; Center for Children's Surgery, CHCO, 13123 E. 16th Ave, Aurora, CO, 80045, USA. .
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Źródło:
Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2021 Nov; Vol. 99 (11), pp. 1571-1583. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cadherin Related Proteins/*genetics
Membrane Proteins/*genetics
Otitis Media/*genetics
Animals ; Child ; Child, Preschool ; Female ; Genetic Predisposition to Disease ; Humans ; Infant ; Male ; Mice, Inbred C57BL ; Microbiota/genetics ; Mutation ; Otitis Media/microbiology ; RNA, Ribosomal, 16S ; Transcriptome
Czasopismo naukowe
Tytuł:
Deep phenotyping of the Cdhr1 mouse validates its use in pre-clinical studies for human CDHR1-associated retinal degeneration.
Autorzy:
Yusuf IH; Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, Oxford University, West Wing, John Radcliffe Hospital, Oxford, OX3 9DU, UK; Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 9DU, UK.
McClements ME; Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, Oxford University, West Wing, John Radcliffe Hospital, Oxford, OX3 9DU, UK; Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 9DU, UK.
MacLaren RE; Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, Oxford University, West Wing, John Radcliffe Hospital, Oxford, OX3 9DU, UK; Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 9DU, UK.
Charbel Issa P; Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, Oxford University, West Wing, John Radcliffe Hospital, Oxford, OX3 9DU, UK; Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Headley Way, Oxford, OX3 9DU, UK. Electronic address: .
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Źródło:
Experimental eye research [Exp Eye Res] 2021 Jul; Vol. 208, pp. 108603. Date of Electronic Publication: 2021 May 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation*
Cadherins/*genetics
DNA/*genetics
Nerve Tissue Proteins/*genetics
Retinal Degeneration/*genetics
Animals ; Cadherin Related Proteins ; Cadherins/biosynthesis ; DNA Mutational Analysis ; Disease Models, Animal ; Electroretinography ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Nerve Tissue Proteins/biosynthesis ; Phenotype ; Retina/metabolism ; Retina/pathology ; Retinal Degeneration/diagnosis ; Retinal Degeneration/metabolism ; Tomography, Optical Coherence/methods
Czasopismo naukowe
Tytuł:
An N-Cadherin 2 expressing epithelial cell subpopulation predicts response to surgery, chemotherapy and immunotherapy in bladder cancer.
Autorzy:
Gouin KH 3rd; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Center for Bioinformatics and Functional Genomics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Ing N; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Center for Bioinformatics and Functional Genomics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Plummer JT; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Center for Bioinformatics and Functional Genomics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Rosser CJ; Department of Surgery (Urology), Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA.
Ben Cheikh B; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Center for Bioinformatics and Functional Genomics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Oh C; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Center for Bioinformatics and Functional Genomics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Chen SS; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Center for Bioinformatics and Functional Genomics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Chan KS; Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA.; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Furuya H; Department of Surgery (Urology), Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA.
Tourtellotte WG; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA.; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Knott SRV; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA. .; Center for Bioinformatics and Functional Genomics, Cedars-Sinai Medical Center, Los Angeles, CA, USA. .; Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA. .
Theodorescu D; Department of Surgery (Urology), Cedars-Sinai Medical Center, Los Angeles, CA, USA. .; Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA, USA. .; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA. .
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Źródło:
Nature communications [Nat Commun] 2021 Aug 12; Vol. 12 (1), pp. 4906. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Cadherins/*genetics
Epithelial Cells/*metabolism
Immunotherapy/*methods
Urinary Bladder Neoplasms/*therapy
Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cadherin Related Proteins ; Cadherins/metabolism ; Catenins/genetics ; Catenins/metabolism ; Gene Expression Profiling/methods ; Humans ; Kaplan-Meier Estimate ; Neoadjuvant Therapy/methods ; Outcome Assessment, Health Care ; Proteomics/methods ; RNA-Seq/methods ; T-Lymphocytes/metabolism ; Urinary Bladder/drug effects ; Urinary Bladder/metabolism ; Urinary Bladder/surgery ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/surgery
Czasopismo naukowe

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