Temat: "Cadherins" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Adiponectin receptor 1 regulates endometrial receptivity via the adenosine monophosphate‑activated protein kinase/E‑cadherin pathway.
Autorzy:: Sarankhuu BE; Priority Research Center, Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon 35365, Republic of Korea.
Jeon HJ; Priority Research Center, Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon 35365, Republic of Korea.
Jeong DU; Priority Research Center, Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon 35365, Republic of Korea.
Park SR; Priority Research Center, Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon 35365, Republic of Korea.
Kim TH; Priority Research Center, Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon 35365, Republic of Korea.
Lee SK; Priority Research Center, Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon 35365, Republic of Korea.
Han AR; I‑Dream Clinic, Department of Obstetrics and Gynecology, Mizmedi Hospital, Seoul 07639, Republic of Korea.
Yu SL; Priority Research Center, Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon 35365, Republic of Korea.
Kang J; Priority Research Center, Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon 35365, Republic of Korea.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2024 Oct; Vol. 30 (4). Date of Electronic Publication: 2024 Aug 19.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, Adiponectin*/metabolism
Receptors, Adiponectin*/genetics
Endometrium*/metabolism
Cadherins*/metabolism
Cadherins*/genetics
AMP-Activated Protein Kinases*/metabolism
Signal Transduction*
Humans ; Female ; Cell Line ; Embryo Implantation ; RNA, Small Interfering/metabolism ; RNA, Small Interfering/genetics ; Adult ; Aminoimidazole Carboxamide/analogs & derivatives ; Ribonucleotides

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Tytuł:: Arrhythmogenic cardiomyopathy-related cadherin variants affect desmosomal binding kinetics.
Autorzy:: Göz M; Department of Physics, Experimental Biophysics and Applied Nanoscience, Bielefeld University, Universitätsstraße 25, Bielefeld, Germany.
Pohl G; Erich & Hanna Klessmann Institute for Cardiovascular Research and Development, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstraße 11, Bad Oeynhausen, Germany.
Steinecker SM; Department of Physics, Experimental Biophysics and Applied Nanoscience, Bielefeld University, Universitätsstraße 25, Bielefeld, Germany.
Walhorn V; Department of Physics, Experimental Biophysics and Applied Nanoscience, Bielefeld University, Universitätsstraße 25, Bielefeld, Germany. Electronic address: .
Milting H; Erich & Hanna Klessmann Institute for Cardiovascular Research and Development, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University Bochum, Georgstraße 11, Bad Oeynhausen, Germany.
Anselmetti D; Department of Physics, Experimental Biophysics and Applied Nanoscience, Bielefeld University, Universitätsstraße 25, Bielefeld, Germany.; Pokaż więcej
Źródło:: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2024 Oct; Vol. 195, pp. 36-44. Date of Electronic Publication: 2024 Jul 28.
Typ publikacji:: Journal Article
MeSH Terms:: Desmosomes*/metabolism
Protein Binding*
Desmoglein 2*/metabolism
Desmoglein 2*/genetics
Arrhythmogenic Right Ventricular Dysplasia*/metabolism
Arrhythmogenic Right Ventricular Dysplasia*/genetics
Desmocollins*/metabolism
Desmocollins*/genetics
Cadherins*/metabolism
Cadherins*/genetics
Humans ; Kinetics ; Mutation ; Microscopy, Atomic Force ; Thermodynamics

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Tytuł:: Polyphyllin VII as a potential medication for targeting epithelial mesenchymal transitionin in thyroid cancer.
Autorzy:: Yu Q; Biomedical Research Institute, Hubei University of Medicine, Shiyan City, Hubei Province, PR China. Electronic address: .
Chen J; Renmin Hospital, Hubei University of Medicine, Shiyan City, Hubei Province, PR China. Electronic address: .
Zhong C; Institute of Basic Medical Sciences, Hubei University of Medicine, Shiyan City, Hubei Province, PR China. Electronic address: .
Yu L; Institute of Basic Medical Sciences, Hubei University of Medicine, Shiyan City, Hubei Province, PR China. Electronic address: .
Zhu Y; Renmin Hospital, Hubei University of Medicine, Shiyan City, Hubei Province, PR China. Electronic address: .
Xi X; Renmin Hospital, Hubei University of Medicine, Shiyan City, Hubei Province, PR China; Institute of Basic Medical Sciences, Hubei University of Medicine, Shiyan City, Hubei Province, PR China; Hubei Key Laboratory of Embryonic Stem Cell Research, Hubei University of Medicine, Shiyan City, Hubei Province, PR China. Electronic address: .
Du B; Biomedical Research Institute, Hubei University of Medicine, Shiyan City, Hubei Province, PR China; Renmin Hospital, Hubei University of Medicine, Shiyan City, Hubei Province, PR China; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Shiyan City, Hubei Province, PR China. Electronic address: .; Pokaż więcej
Źródło:: Journal of pharmacological sciences [J Pharmacol Sci] 2024 Oct; Vol. 156 (2), pp. 49-56. Date of Electronic Publication: 2024 Jul 06.
Typ publikacji:: Journal Article
MeSH Terms:: Epithelial-Mesenchymal Transition*/drug effects
Epithelial-Mesenchymal Transition*/genetics
Thyroid Neoplasms*/drug therapy
Thyroid Neoplasms*/pathology
Thyroid Neoplasms*/genetics
Cell Proliferation*/drug effects
Cadherins*/metabolism
Cadherins*/genetics
Saponins*/pharmacology
Saponins*/therapeutic use
Cell Movement*/drug effects
Humans ; Cell Line, Tumor ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; Dose-Response Relationship, Drug ; Gene Expression/drug effects ; Molecular Targeted Therapy ; Antineoplastic Agents/pharmacology

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Tytuł:: Generation and characterization of a human iPSC line expressing EGFP-tagged CDH1, KSCBi002-A-3.
Autorzy:: Oh JY; Division of Intractable Disease Research, Korea National Institute of Health, Cheong-Ju 28160, Republic of Korea.
Yoo DH; Division of Intractable Disease Research, Korea National Institute of Health, Cheong-Ju 28160, Republic of Korea.
Im YS; Division of Intractable Disease Research, Korea National Institute of Health, Cheong-Ju 28160, Republic of Korea.
Kim YO; Division of Intractable Disease Research, Korea National Institute of Health, Cheong-Ju 28160, Republic of Korea. Electronic address: .; Pokaż więcej
Źródło:: Stem cell research [Stem Cell Res] 2024 Oct; Vol. 80, pp. 103510. Date of Electronic Publication: 2024 Jul 25.
Typ publikacji:: Journal Article
MeSH Terms:: Induced Pluripotent Stem Cells*/metabolism
Induced Pluripotent Stem Cells*/cytology
Cadherins*/metabolism
Cadherins*/genetics
Green Fluorescent Proteins*/metabolism
Green Fluorescent Proteins*/genetics
Humans ; Cell Line ; CRISPR-Cas Systems ; Antigens, CD/metabolism ; Antigens, CD/genetics ; Cell Differentiation

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Skocz do pozycji: 5.

Tytuł:: Expression profiles of cadherin 17 and claudin 18.2 in comparison with peptide hormonal expression in pancreatic neuroendocrine tumours: Implications for targeted immunotherapy.
Autorzy:: Maeda K; Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine, Matsumoto, Japan. Electronic address: k_.
Uehara T; Department of Laboratory Medicine, Shinshu University School of Medicine, Matsumoto, Japan. Electronic address: .
Hosoda W; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan. Electronic address: .
Kuraishi Y; Department of Gastroenterology, Aichi Cancer Center, Nagoya, Japan. Electronic address: .
Ota H; Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine, Matsumoto, Japan; Department of Medical Sciences, Shinshu University Graduate School of Medicine, Science and Technology, Matsumoto, Japan. Electronic address: .; Pokaż więcej
Źródło:: Pathology, research and practice [Pathol Res Pract] 2024 Oct; Vol. 262, pp. 155537. Date of Electronic Publication: 2024 Aug 12.
Typ publikacji:: Journal Article; Comparative Study
MeSH Terms:: Pancreatic Neoplasms*/pathology
Pancreatic Neoplasms*/metabolism
Pancreatic Neoplasms*/therapy
Claudins*/analysis
Claudins*/metabolism
Neuroendocrine Tumors*/pathology
Neuroendocrine Tumors*/metabolism
Cadherins*/metabolism
Cadherins*/analysis
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/metabolism
Humans ; Immunotherapy/methods ; Male ; Middle Aged ; Female ; Adult ; Aged ; Immunohistochemistry

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Tytuł:: Differential prognostic impact and potential molecular mechanisms of PCDHGA12 expression in lung adenocarcinoma and squamous cell carcinoma.
Autorzy:: Xu X; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Zhang J; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Yao T; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Zhao X; Department of R&D, Zhejiang Yunying Medical Technology Co., Ltd., Jiaxing 314006, China.
Wu Q; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Lu C; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Guo X; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Xie S; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Qiu L; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Bi R; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Xue H; Department of Pulmonology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China. Electronic address: .; Pokaż więcej
Źródło:: International immunopharmacology [Int Immunopharmacol] 2024 Sep 30; Vol. 139, pp. 112727. Date of Electronic Publication: 2024 Jul 26.
Typ publikacji:: Journal Article
MeSH Terms:: Lung Neoplasms*/genetics
Lung Neoplasms*/mortality
Lung Neoplasms*/immunology
Gene Expression Regulation, Neoplastic*
Carcinoma, Squamous Cell*/genetics
Carcinoma, Squamous Cell*/mortality
Carcinoma, Squamous Cell*/immunology
Cadherins*/genetics
Cadherins*/metabolism
Adenocarcinoma of Lung*/genetics
Adenocarcinoma of Lung*/mortality
Adenocarcinoma of Lung*/immunology
Adenocarcinoma of Lung*/metabolism
Humans ; Prognosis ; Biomarkers, Tumor/genetics ; Mutation ; Male ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/immunology ; Female

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Tytuł:: Gamma-protocadherins regulate dendrite self-recognition and dynamics to drive self-avoidance.
Autorzy:: Ing-Esteves S; Program for Neuroscience and Mental Health, Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Lefebvre JL; Program for Neuroscience and Mental Health, Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada. Electronic address: .; Pokaż więcej
Źródło:: Current biology : CB [Curr Biol] 2024 Sep 23; Vol. 34 (18), pp. 4224-4239.e4. Date of Electronic Publication: 2024 Aug 29.
Typ publikacji:: Journal Article
MeSH Terms:: Dendrites*/physiology
Dendrites*/metabolism
Cadherins*/metabolism
Cadherins*/genetics
Amacrine Cells*/metabolism
Amacrine Cells*/physiology
Cadherin Related Proteins*
Animals ; Mice ; Retina/metabolism ; Morphogenesis

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Skocz do pozycji: 8.

Tytuł:: Molecular Crosstalk Between Adherens Junction Proteins, E-cadherin and Nectin-4.
Autorzy:: Dash S; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India.
Biswas J; School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & 2B, Raja Subodh Chandra Mallick Road, Jadavpur, Kolkata 700032, West Bengal, India.
Goswami S; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India.
Mukherjee S; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India.
Ganguli N; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India.
Duraivelan K; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India.
Mondal S; School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & 2B, Raja Subodh Chandra Mallick Road, Jadavpur, Kolkata 700032, West Bengal, India.
Mukhopadhyay R; School of Biological Sciences, Indian Association for the Cultivation of Science, 2A & 2B, Raja Subodh Chandra Mallick Road, Jadavpur, Kolkata 700032, West Bengal, India. Electronic address: .
Samanta D; Department of Bioscience and Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India. Electronic address: .; Pokaż więcej
Źródło:: Journal of molecular biology [J Mol Biol] 2024 Sep 15; Vol. 436 (18), pp. 168709. Date of Electronic Publication: 2024 Jul 14.
Typ publikacji:: Journal Article
MeSH Terms:: Adherens Junctions*/metabolism
Cadherins*/metabolism
Cadherins*/genetics
Cadherins*/chemistry
Cell Adhesion Molecules*/metabolism
Cell Adhesion Molecules*/genetics
Microscopy, Atomic Force*
Nectins*/metabolism
Nectins*/genetics
Protein Binding*
Humans ; Antigens, CD/metabolism ; Antigens, CD/genetics ; Cell Adhesion ; Kinetics ; Surface Plasmon Resonance

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Skocz do pozycji: 9.

Tytuł:: Synergism of Cry1 Toxins by a Fusion Protein Derived from a Cadherin Fragment and an Antibody Peptide.
Autorzy:: Gao M; State Key Laboratory Cultivation Base, Ministry of Science and Technology─Jiangsu Key Laboratory for Food Quality and Safety, Institute of Food Safety and Nutrition, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Zhong J; State Key Laboratory Cultivation Base, Ministry of Science and Technology─Jiangsu Key Laboratory for Food Quality and Safety, Institute of Food Safety and Nutrition, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Lu L; State Key Laboratory Cultivation Base, Ministry of Science and Technology─Jiangsu Key Laboratory for Food Quality and Safety, Institute of Food Safety and Nutrition, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Li Y; State Key Laboratory Cultivation Base, Ministry of Science and Technology─Jiangsu Key Laboratory for Food Quality and Safety, Institute of Food Safety and Nutrition, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
Zhang Z; State Key Laboratory Cultivation Base, Ministry of Science and Technology─Jiangsu Key Laboratory for Food Quality and Safety, Institute of Food Safety and Nutrition, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.; Pokaż więcej
Źródło:: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Sep 11; Vol. 72 (36), pp. 19689-19698. Date of Electronic Publication: 2024 Aug 27.
Typ publikacji:: Journal Article
MeSH Terms:: Cadherins*/genetics
Cadherins*/metabolism
Cadherins*/immunology
Cadherins*/chemistry
Hemolysin Proteins*/chemistry
Hemolysin Proteins*/pharmacology
Hemolysin Proteins*/immunology
Hemolysin Proteins*/genetics
Endotoxins*/immunology
Endotoxins*/chemistry
Endotoxins*/pharmacology
Endotoxins*/metabolism
Endotoxins*/genetics
Bacillus thuringiensis Toxins*/chemistry
Bacillus thuringiensis Toxins*/pharmacology
Moths*/drug effects
Bacterial Proteins*/chemistry
Bacterial Proteins*/genetics
Bacterial Proteins*/immunology
Bacterial Proteins*/metabolism
Bacterial Proteins*/pharmacology
Recombinant Fusion Proteins*/chemistry
Recombinant Fusion Proteins*/pharmacology
Recombinant Fusion Proteins*/genetics
Recombinant Fusion Proteins*/immunology
Recombinant Fusion Proteins*/metabolism
Insect Proteins*/immunology
Insect Proteins*/chemistry
Insect Proteins*/genetics
Insect Proteins*/metabolism
Larva*/growth & development
Animals ; Peptides/chemistry ; Peptides/immunology ; Peptides/pharmacology ; Antibodies/immunology ; Antibodies/chemistry ; Bacillus thuringiensis/chemistry ; Bacillus thuringiensis/genetics ; Bacillus thuringiensis/metabolism ; Insecticides/chemistry ; Insecticides/pharmacology ; Pest Control, Biological

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Skocz do pozycji: 10.

Tytuł:: Proteomics and digital subtraction angiography approaches reveal CDH18 as a potential target for therapy of moyamoya disease.
Autorzy:: Guo D; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Dong Y; Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China.
Li H; Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Li H; Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China. .
Yang B; Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, 450052, China. .; Pokaż więcej
Źródło:: Biology direct [Biol Direct] 2024 Sep 05; Vol. 19 (1), pp. 76. Date of Electronic Publication: 2024 Sep 05.
Typ publikacji:: Journal Article
MeSH Terms:: Moyamoya Disease*/genetics
Moyamoya Disease*/metabolism
Proteomics*/methods
Cadherins*/metabolism
Cadherins*/genetics
Angiography, Digital Subtraction*
Humans ; Male ; Cell Proliferation ; Female ; Cell Movement ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/metabolism ; Adult ; Middle Aged

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Skocz do pozycji: 11.

Tytuł:: Ubiquitination of VE-cadherin regulates inflammation-induced vascular permeability in vivo.
Autorzy:: Wilkens M; Max Planck Institute for Molecular Biomedicine, D-48149, Muenster, Germany.
Holtermann L; Max Planck Institute for Molecular Biomedicine, D-48149, Muenster, Germany.
Stahl AK; Max Planck Institute for Molecular Biomedicine, D-48149, Muenster, Germany.
Stegmeyer RI; Max Planck Institute for Molecular Biomedicine, D-48149, Muenster, Germany.
Nottebaum AF; Max Planck Institute for Molecular Biomedicine, D-48149, Muenster, Germany.
Vestweber D; Max Planck Institute for Molecular Biomedicine, D-48149, Muenster, Germany. .; Pokaż więcej
Źródło:: EMBO reports [EMBO Rep] 2024 Sep; Vol. 25 (9), pp. 4013-4032. Date of Electronic Publication: 2024 Aug 07.
Typ publikacji:: Journal Article
MeSH Terms:: Antigens, CD*/metabolism
Antigens, CD*/genetics
Cadherins*/metabolism
Cadherins*/genetics
Capillary Permeability*
Inflammation*/metabolism
Inflammation*/genetics
Ubiquitination*
Animals ; Humans ; Mice ; Endocytosis ; Gene Knock-In Techniques ; Histamine/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Lipopolysaccharides/pharmacology ; Lung/metabolism ; Lysosomes/metabolism ; Skin/metabolism

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Tytuł:: Generation of an induced pluripotent stem cell line from a late-onset, progressive high frequency hearing loss patient due to mutation in CDH23.
Autorzy:: Arai D; Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Takahashi-Shibata M; Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Ukaji T; Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Tsutsumi H; Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Tajima S; Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Nishio SY; Department of Hearing Implant Science, Shinshu University School of Medicine, Nagano, Japan.
Ishikawa KI; Center for Genomic and Regenerative Medicine, Juntendo University School of Medicine, Tokyo, Japan; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Akamatsu W; Center for Genomic and Regenerative Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Matsumoto F; Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Ikeda K; Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Usami SI; Department of Hearing Implant Science, Shinshu University School of Medicine, Nagano, Japan.
Kamiya K; Department of Otorhinolaryngology, Juntendo University Faculty of Medicine, Tokyo, Japan. Electronic address: .; Pokaż więcej
Źródło:: Stem cell research [Stem Cell Res] 2024 Sep; Vol. 79, pp. 103471. Date of Electronic Publication: 2024 Jun 12.
Typ publikacji:: Journal Article
MeSH Terms:: Induced Pluripotent Stem Cells*/metabolism
Cadherins*/genetics
Cadherins*/metabolism
Mutation*
Hearing Loss*/genetics
Hearing Loss*/pathology
Humans ; Cell Line ; Cell Differentiation ; Male ; Cadherin Related Proteins

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Skocz do pozycji: 13.

Tytuł:: Notch transcriptional target tmtc1 maintains vascular homeostasis.
Autorzy:: Paik NY; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Neethling J; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Anwar M; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Gupta P; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Sanborn MA; Department of Biochemistry, University of Illinois at Chicago College of Medicine, Chicago, IL, USA.
Shen Z; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Bandara T; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Hyun J; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Naiche LA; Department of Physiology and Biophysics, University of Illinois College of Medicine, Chicago, IL, 60612, USA.
Kitajewski JK; Department of Physiology and Biophysics, University of Illinois College of Medicine, Chicago, IL, 60612, USA.
Rehman J; Department of Biochemistry, University of Illinois at Chicago College of Medicine, Chicago, IL, USA.
Shin JW; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Mehta D; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA.
Pajcini KV; Department of Pharmacology and Regenerative Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL, 60612, USA. .; Pokaż więcej
Źródło:: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Aug 27; Vol. 81 (1), pp. 370. Date of Electronic Publication: 2024 Aug 27.
Typ publikacji:: Journal Article
MeSH Terms:: Cadherins*/metabolism
Cadherins*/genetics
Homeostasis*
Endothelial Cells*/metabolism
Signal Transduction*
Lung*/metabolism
Lung*/blood supply
Antigens, CD*/metabolism
Antigens, CD*/genetics
Animals ; Mice ; Humans ; Receptors, Notch/metabolism ; Receptors, Notch/genetics ; Mice, Transgenic ; Capillary Permeability ; Receptor, Notch1/metabolism ; Receptor, Notch1/genetics ; Adherens Junctions/metabolism ; Mice, Inbred C57BL

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Tytuł:: Small RNA activation of CDH13 expression overcome BCR-ABL1-independent imatinib-resistance and their signaling pathway studies in chronic myeloid leukemia.
Autorzy:: Su R; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou, China.; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China.; Antisense Biopharmaceutical Technology Co Ltd, Guangzhou, China.; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, China.
Wen Z; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou, China.; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China.; Antisense Biopharmaceutical Technology Co Ltd, Guangzhou, China.; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, China.
Zhan X; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou, China.; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China.; Antisense Biopharmaceutical Technology Co Ltd, Guangzhou, China.; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, China.
Long Y; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou, China.; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China.; Antisense Biopharmaceutical Technology Co Ltd, Guangzhou, China.; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, China.
Wang X; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou, China.; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China.; Antisense Biopharmaceutical Technology Co Ltd, Guangzhou, China.; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, China.
Li C; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou, China.; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China.; Antisense Biopharmaceutical Technology Co Ltd, Guangzhou, China.; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, China.
Su Y; Department of Cell Biology & Institute of Biomedicine, National Engineering Research Center of Genetic Medicine, MOE Key Laboratory of Tumor Molecular Biology, Guangdong Provincial Key Laboratory of Bioengineering Medicine, College of Life Science and Technology, Jinan University, Guangzhou, China. .
Fei J; Department of Biochemistry and Molecular Biology, Medical College of Jinan University, Guangzhou, China. .; Guangdong Engineering Technology Research Center of Drug Development for Small Nucleic Acids, Guangzhou, China. .; Antisense Biopharmaceutical Technology Co Ltd, Guangzhou, China. .; State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, China. .; Pokaż więcej
Źródło:: Cell death & disease [Cell Death Dis] 2024 Aug 23; Vol. 15 (8), pp. 615. Date of Electronic Publication: 2024 Aug 23.
Typ publikacji:: Journal Article
MeSH Terms:: Imatinib Mesylate*/pharmacology
Imatinib Mesylate*/therapeutic use
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/pathology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/metabolism
Drug Resistance, Neoplasm*/genetics
Drug Resistance, Neoplasm*/drug effects
Cadherins*/metabolism
Cadherins*/genetics
Signal Transduction*/drug effects
Fusion Proteins, bcr-abl*/metabolism
Fusion Proteins, bcr-abl*/genetics
Humans ; K562 Cells ; RNA, Small Interfering/metabolism ; Animals ; Apoptosis/drug effects ; Mice ; NF-kappa B/metabolism ; Mice, Nude ; Cell Line, Tumor

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Skocz do pozycji: 15.

Tytuł:: Insights into E-Cadherin Impairment in CDH1 -Unaltered Invasive Lobular Carcinoma: A Comprehensive Bioinformatic Study.
Autorzy:: Uchida S; Division of Diagnostic Pathology, Kikuna Memorial Hospital, 4-4-27, Kikuna, Kohoku-ku, Yokohama 222-0011, Japan.; Division of Pathology, Shizuoka Cancer Center, Shizuoka 411-8777, Japan.; Department of Human Pathology, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Sugino T; Division of Pathology, Shizuoka Cancer Center, Shizuoka 411-8777, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 17; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 17.
Typ publikacji:: Journal Article
MeSH Terms:: Cadherins*/genetics
Cadherins*/metabolism
Carcinoma, Lobular*/genetics
Carcinoma, Lobular*/metabolism
Carcinoma, Lobular*/pathology
Antigens, CD*/metabolism
Antigens, CD*/genetics
Computational Biology*/methods
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Breast Neoplasms*/metabolism
Gene Expression Regulation, Neoplastic*
DNA Methylation*
Humans ; Female ; Mutation ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Neoplasm Invasiveness

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Skocz do pozycji: 16.

Tytuł:: Multiplex Sensing of Biomarkers on the Cancer Cell Surface by an Epithelial-Mesenchymal Transition (EMT) Sensing Panel Enables Precise Differentiating of Cancer Cells at Various EMT Stages.
Autorzy:: Wang S; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Guo Y; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Wang X; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Zhang X; Institute of Medical Technology, Shanxi Medical University, Taiyuan 030001, China.
Yang T; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.
Wang JH; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China.; Pokaż więcej
Źródło:: Analytical chemistry [Anal Chem] 2024 Aug 13; Vol. 96 (32), pp. 13270-13277. Date of Electronic Publication: 2024 Aug 02.
Typ publikacji:: Journal Article
MeSH Terms:: Epithelial-Mesenchymal Transition*
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/metabolism
Cadherins*/analysis
Cadherins*/metabolism
Humans ; Fluorescent Dyes/chemistry ; Cell Line, Tumor ; Epithelial Cell Adhesion Molecule/metabolism ; MCF-7 Cells ; Boronic Acids/chemistry ; N-Acetylneuraminic Acid/analysis ; N-Acetylneuraminic Acid/metabolism

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Skocz do pozycji: 17.

Tytuł:: Human Stimulator of Interferon Genes Promotes Rhinovirus C Replication in Mouse Cells In Vitro and In Vivo.
Autorzy:: Goldstein ME; Department of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, 3134 Biosciences Research Building, University of Maryland, College Park, MD 20742, USA.
Ignacio MA; Department of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, 3134 Biosciences Research Building, University of Maryland, College Park, MD 20742, USA.
Loube JM; Department of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, 3134 Biosciences Research Building, University of Maryland, College Park, MD 20742, USA.
Whorton MR; Vollum Institute, Oregon Health and Science University, Portland, OR 97239, USA.
Scull MA; Department of Cell Biology and Molecular Genetics, Maryland Pathogen Research Institute, 3134 Biosciences Research Building, University of Maryland, College Park, MD 20742, USA.; Pokaż więcej
Źródło:: Viruses [Viruses] 2024 Aug 10; Vol. 16 (8). Date of Electronic Publication: 2024 Aug 10.
Typ publikacji:: Journal Article
MeSH Terms:: Virus Replication*
Mice, Transgenic*
Cadherins*/genetics
Cadherins*/metabolism
Cadherin Related Proteins*
Animals ; Mice ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Epithelial Cells/virology ; Disease Models, Animal ; Enterovirus/physiology ; Enterovirus/genetics ; Cell Line ; Picornaviridae Infections/virology ; Mice, Inbred C57BL ; Lung/virology
SCR Organism:: Rhinovirus C

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Skocz do pozycji: 18.

Tytuł:: YTHDF1 promotes the osteolytic bone metastasis of breast cancer via inducing EZH2 and CDH11 translation.
Autorzy:: Wang S; Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Nuclear Medicine, Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Xu L; Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Wang D; Department of Nuclear Medicine, Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Zhao S; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Li K; Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Ma F; Shanghai Key Laboratory of Compound Chinese Medicines, The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, China; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China.
Yao Q; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Zhang Y; Department of Anesthesiology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Wu Z; Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Shao Y; Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: .
Song S; Department of Nuclear Medicine, Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: .
Yan W; Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: .; Pokaż więcej
Źródło:: Cancer letters [Cancer Lett] 2024 Aug 10; Vol. 597, pp. 217047. Date of Electronic Publication: 2024 Jun 12.
Typ publikacji:: Journal Article
MeSH Terms:: Bone Neoplasms*/secondary
Bone Neoplasms*/genetics
Bone Neoplasms*/metabolism
Breast Neoplasms*/pathology
Breast Neoplasms*/genetics
Breast Neoplasms*/metabolism
Cadherins*/metabolism
Cadherins*/genetics
Enhancer of Zeste Homolog 2 Protein*/metabolism
Enhancer of Zeste Homolog 2 Protein*/genetics
Osteolysis*/genetics
RNA-Binding Proteins*/genetics
RNA-Binding Proteins*/metabolism
Animals ; Female ; Humans ; Mice ; Cell Differentiation ; Cell Line, Tumor ; Cell Movement ; Gene Expression Regulation, Neoplastic ; Osteoclasts/metabolism ; Osteoclasts/pathology

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Skocz do pozycji: 19.

Tytuł:: circ0005027 Acting as a ceRNA Affects the Malignant Biological Behavior of Hypopharyngeal Squamous Cell Carcinoma by Modulating miR-548c-3p/CDH1 Axis.
Autorzy:: Yang X; The Second Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Rd, Kunming, 650032, Yunnan, China.
Feng C; Department of Otolaryngology, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, 650034, Yunnan, China.
Jiang D; The Second Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Rd, Kunming, 650032, Yunnan, China.
Xu X; The Second Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Rd, Kunming, 650032, Yunnan, China.
Zhang Y; Department of Pathology and Pathophysiology, School of Basic Medical Science, Kunming Medical University, Kunming, 650500, Yunnan, China.
Wang J; Department of Otolaryngology, The Second People's Hospital of Yunnan Province, Kunming, 650021, Yunnan, China.
He X; The Second Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Rd, Kunming, 650032, Yunnan, China. .; Pokaż więcej
Źródło:: Biochemical genetics [Biochem Genet] 2024 Aug; Vol. 62 (4), pp. 2853-2868. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:: Journal Article
MeSH Terms:: MicroRNAs*/genetics
MicroRNAs*/metabolism
Cadherins*/genetics
Cadherins*/metabolism
Hypopharyngeal Neoplasms*/genetics
Hypopharyngeal Neoplasms*/metabolism
Hypopharyngeal Neoplasms*/pathology
Antigens, CD*/genetics
Antigens, CD*/metabolism
Humans ; Gene Expression Regulation, Neoplastic ; Squamous Cell Carcinoma of Head and Neck/genetics ; Squamous Cell Carcinoma of Head and Neck/metabolism ; Squamous Cell Carcinoma of Head and Neck/pathology ; Cell Line, Tumor ; Cell Proliferation ; Carcinoma, Squamous Cell/genetics ; Carcinoma, Squamous Cell/metabolism ; Carcinoma, Squamous Cell/pathology ; Female ; Apoptosis ; RNA, Competitive Endogenous

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Skocz do pozycji: 20.

Tytuł:: Advantages of automated immunostain analyses for complex membranous immunostains: An exemplar investigating loss of E-cadherin expression in colorectal cancer.
Autorzy:: Sculthorpe D; Translational Medical Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, United Kingdom. Electronic address: .
Denton A; Translational Medical Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Rusnita D; Translational Medical Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Fadhil W; Translational Medical Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Ilyas M; Translational Medical Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, United Kingdom; Department of Histopathology, Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham, United Kingdom.
Mukherjee A; Translational Medical Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, United Kingdom; Department of Histopathology, Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham, United Kingdom.; Pokaż więcej
Źródło:: Pathology, research and practice [Pathol Res Pract] 2024 Aug; Vol. 260, pp. 155470. Date of Electronic Publication: 2024 Jul 15.
Typ publikacji:: Journal Article
MeSH Terms:: Cadherins*/metabolism
Cadherins*/analysis
Colorectal Neoplasms*/pathology
Colorectal Neoplasms*/metabolism
Biomarkers, Tumor*/analysis
Biomarkers, Tumor*/metabolism
Humans ; Male ; Female ; Middle Aged ; Aged ; Immunohistochemistry/methods ; Tissue Array Analysis ; Prognosis ; Antigens, CD/metabolism ; Aged, 80 and over ; Adult

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