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Wyszukujesz frazę ""Cahill, CM"" wg kryterium: Autor


Tytuł:
Targeting PSEN1 by lnc-CYP3A43-2/miR-29b-2-5p to Reduce β Amyloid Plaque Formation and Improve Cognition Function.
Autorzy:
Wuli W; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Department of Life Science, National Dong Hwa University, Hualien 974301, Taiwan.
Lin SZ; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Department of Neurology, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.
Chen SP; Buddhist Tzu Chi Stem Cells Centre, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.
Tannous BA; Neurochemistry Laboratory, Department of Psychiatry-Neuroscience, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, Boston, MA 02129, USA.
Huang WS; Department of Nuclear Medicine, Taipei Medical University Hospital, Taipei 110301, Taiwan.
Woon PY; Taiwan Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien 97004, Taiwan.
Wu YC; Graduate Institute of Integrated Medicine, China Medical University, Taichung City 404, Taiwan.; Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung City 404, Taiwan.; The Biotechnology Department, College of Medical and Health Science, Asia University, Taichung City 404, Taiwan.
Yang HH; Department of Medical Research, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.
Chen YC; Department of Medicine, Mackay Medical College, New Taipei City 25245, Taiwan.
Fleming RL; Neurochemistry Laboratory, Department of Psychiatry-Neuroscience, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, Boston, MA 02129, USA.
Rogers JT; Neurochemistry Laboratory, Department of Psychiatry-Neuroscience, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, Boston, MA 02129, USA.
Cahill CM; Neurochemistry Laboratory, Department of Psychiatry-Neuroscience, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Charlestown, Boston, MA 02129, USA.
Ho TJ; Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien 97004, Taiwan.
Chiou TW; Department of Life Science, National Dong Hwa University, Hualien 974301, Taiwan.
Harn HJ; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Department of Pathology, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 11; Vol. 23 (18). Date of Electronic Publication: 2022 Sep 11.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
MicroRNAs*/metabolism
RNA, Long Noncoding*/genetics
Amyloid Precursor Protein Secretases/genetics ; Amyloid beta-Peptides/genetics ; Amyloid beta-Peptides/metabolism ; Animals ; Biotin ; Cognition ; Mice ; Plaque, Amyloid ; Presenilin-1/genetics
Czasopismo naukowe
Tytuł:
Alpha-Synuclein in Alcohol Use Disorder, Connections with Parkinson's Disease and Potential Therapeutic Role of 5' Untranslated Region-Directed Small Molecules.
Autorzy:
Cahill CM; Neurochemistry Laboratory, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
Aleyadeh R; Weill Cornell Medicine-Qatar, Qatar Foundation, Doha 24144, Qatar.
Gao J; Department of Clinical Psychology, Qilu Hospital of Shandong University, Qingdao 266011, China.
Wang C; Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
Rogers JT; Neurochemistry Laboratory, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
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Źródło:
Biomolecules [Biomolecules] 2020 Oct 21; Vol. 10 (10). Date of Electronic Publication: 2020 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Alcoholism/*genetics
Parkinson Disease/*genetics
Small Molecule Libraries/*chemistry
alpha-Synuclein/*genetics
5' Untranslated Regions/genetics ; Alcoholism/pathology ; Alcoholism/therapy ; Brain/drug effects ; Brain/metabolism ; Gene Expression Regulation/drug effects ; Humans ; Lewy Bodies/drug effects ; Lewy Bodies/metabolism ; Neurons/drug effects ; Neurons/metabolism ; Parkinson Disease/pathology ; Small Molecule Libraries/therapeutic use ; alpha-Synuclein/therapeutic use
Czasopismo naukowe
Tytuł:
Biomarkers of environmental manganese exposure and associations with childhood neurodevelopment: a systematic review and meta-analysis.
Autorzy:
Liu W; Department of Nutrition, Precision Nutrition Innovation Center, School of Public Health, Zhengzhou University, Zhengzhou, China.
Xin Y; Department of Nutrition, Precision Nutrition Innovation Center, School of Public Health, Zhengzhou University, Zhengzhou, China.
Li Q; Department of Nutrition, Precision Nutrition Innovation Center, School of Public Health, Zhengzhou University, Zhengzhou, China.
Shang Y; Department of Nutrition, Precision Nutrition Innovation Center, School of Public Health, Zhengzhou University, Zhengzhou, China.
Ping Z; Department of Nutrition, Precision Nutrition Innovation Center, School of Public Health, Zhengzhou University, Zhengzhou, China.
Min J; The First Affiliated Hospital, School of Public Health, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Cahill CM; Neurochemistry Laboratory, Department of Psychiatry-Neuroscience, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.
Rogers JT; Neurochemistry Laboratory, Department of Psychiatry-Neuroscience, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA. .
Wang F; Department of Nutrition, Precision Nutrition Innovation Center, School of Public Health, Zhengzhou University, Zhengzhou, China. .; The First Affiliated Hospital, School of Public Health, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China. .
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Źródło:
Environmental health : a global access science source [Environ Health] 2020 Oct 02; Vol. 19 (1), pp. 104. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji:
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms:
Child Development/*drug effects
Environmental Exposure/*adverse effects
Environmental Pollutants/*adverse effects
Manganese/*adverse effects
Neurodevelopmental Disorders/*chemically induced
Biomarkers/analysis ; Child ; Hair/chemistry ; Humans ; Intelligence/drug effects
Czasopismo naukowe
Tytuł:
Targeting the Iron-Response Elements of the mRNAs for the Alzheimer's Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity.
Autorzy:
Rogers JT; Neurochemistry Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. .
Xia N; Molecular Neurobiology Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. .
Wong A; Neurochemistry Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. .
Bakshi R; Molecular Neurobiology Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. .
Cahill CM; Neurochemistry Laboratory, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Feb 25; Vol. 20 (4). Date of Electronic Publication: 2019 Feb 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amyloid beta-Protein Precursor/*genetics
Ferritins/*genetics
Iron-Regulatory Proteins/*genetics
Lead Poisoning, Nervous System/*drug therapy
Manganese Poisoning/*drug therapy
Muscarinic Agonists/*therapeutic use
Quinuclidines/*therapeutic use
Response Elements/*physiology
Thiophenes/*therapeutic use
5' Untranslated Regions/drug effects ; Acute Disease ; Alzheimer Disease/metabolism ; Animals ; Down Syndrome/metabolism ; Humans ; Iron/metabolism ; Mice ; Muscarinic Agonists/pharmacology ; Neurons/metabolism ; Protein Biosynthesis/drug effects ; Quinuclidines/pharmacology ; RNA, Messenger/genetics ; Rats ; Thiophenes/pharmacology
Czasopismo naukowe
Tytuł:
Differential Expression of the Activator Protein 1 Transcription Factor Regulates Interleukin-1ß Induction of Interleukin 6 in the Developing Enterocyte.
Autorzy:
Cahill CM; Neurochemistry Laboratory, Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Charlestown, Massachusetts, United States of America.
Zhu W; Mucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital for Children, and Harvard Medical School, Charlestown, Massachusetts, United States of America.
Oziolor E; Department. of Environmental Science, Baylor University One Bear Place #97266, Waco, Texas, United States of America.
Yang YJ; Departments of Pediatrics and Internal Medicine, National Cheng Kung University, Tainan, Taiwan.
Tam B; Neurochemistry Laboratory, Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Charlestown, Massachusetts, United States of America.
Rajanala S; Neurochemistry Laboratory, Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Charlestown, Massachusetts, United States of America.
Rogers JT; Neurochemistry Laboratory, Department of Psychiatry, Massachusetts General Hospital, and Harvard Medical School, Charlestown, Massachusetts, United States of America.
Walker WA; Mucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital for Children, and Harvard Medical School, Charlestown, Massachusetts, United States of America.
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Źródło:
PloS one [PLoS One] 2016 Jan 22; Vol. 11 (1), pp. e0145184. Date of Electronic Publication: 2016 Jan 22 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Enterocytes/*physiology
Interleukin-1beta/*metabolism
Interleukin-6/*metabolism
Transcription Factor AP-1/*metabolism
Animals ; Cell Line ; Enterocytes/cytology ; Enterocytes/drug effects ; Heterografts ; Humans ; Interleukin-1beta/pharmacology ; Interleukin-6/genetics ; Intestines/cytology ; Intestines/embryology ; JNK Mitogen-Activated Protein Kinases/metabolism ; Mice, SCID ; Mitogen-Activated Protein Kinase 8/metabolism ; NF-kappa B/metabolism ; Organ Culture Techniques ; Phosphorylation ; Response Elements ; Signal Transduction ; Transcription Factor AP-1/genetics ; Transcription Factors/genetics ; Transcription Factors/metabolism ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe

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