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Tytuł:
The phenotype of cryopreserved platelets influences the formation of platelet-leukocyte aggregates in an in vitro model.
Autorzy:
Winskel-Wood B; Research & Development, Australian Red Cross Lifeblood, Sydney, NSW, Australia.; School of Life Sciences, University of Technology Sydney, Sydney, NSW, Australia.
Padula MP; School of Life Sciences, University of Technology Sydney, Sydney, NSW, Australia.
Marks DC; Research & Development, Australian Red Cross Lifeblood, Sydney, NSW, Australia.; Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.
Johnson L; Research & Development, Australian Red Cross Lifeblood, Sydney, NSW, Australia.; School of Life Sciences, University of Technology Sydney, Sydney, NSW, Australia.
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Źródło:
Platelets [Platelets] 2023 Dec; Vol. 34 (1), pp. 2206916.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelets*/metabolism
Monocytes*/metabolism
Calcimycin/metabolism ; Calcimycin/pharmacology ; Phenotype ; Cryopreservation/methods ; Polyesters/metabolism ; P-Selectin/metabolism ; Platelet Activation
Czasopismo naukowe
Tytuł:
Effects of platelets activated by different agonists on fibrin formation and thrombin generation.
Autorzy:
Muravlev IA; National Medical Research Center of Cardiology, Russian Ministry of Health, Moscow, Russian Federation.
Dobrovolsky AB; National Medical Research Center of Cardiology, Russian Ministry of Health, Moscow, Russian Federation.
Antonova OA; National Medical Research Center of Cardiology, Russian Ministry of Health, Moscow, Russian Federation.
Khaspekova SG; National Medical Research Center of Cardiology, Russian Ministry of Health, Moscow, Russian Federation.
Mazurov AV; National Medical Research Center of Cardiology, Russian Ministry of Health, Moscow, Russian Federation.
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Źródło:
Platelets [Platelets] 2023 Dec; Vol. 34 (1), pp. 2139365. Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Thrombin*/pharmacology
Thrombin*/metabolism
Blood Platelets*/metabolism
Humans ; Fibrin/metabolism ; Calcimycin/metabolism ; Calcimycin/pharmacology ; Arachidonic Acid/pharmacology ; Arachidonic Acid/metabolism ; Phosphatidylserines/metabolism ; Collagen/pharmacology ; Collagen/metabolism ; Adenosine Diphosphate/pharmacology ; Adenosine Diphosphate/metabolism
Czasopismo naukowe
Tytuł:
Inhibiting Neutrophil Extracellular Traps Protects against Ultraviolet B-Induced Skin Damage: Effects of Hochu-ekki-to and DNase I.
Autorzy:
Inaba I; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 3500-3, Minamitamagaki, Suzuka 513-8670, Japan.
Hiramoto K; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 3500-3, Minamitamagaki, Suzuka 513-8670, Japan.
Yamate Y; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 3500-3, Minamitamagaki, Suzuka 513-8670, Japan.
Morita A; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 3500-3, Minamitamagaki, Suzuka 513-8670, Japan.
Tsutsumi T; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 3500-3, Minamitamagaki, Suzuka 513-8670, Japan.
Yasuda H; Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Misasagi 5, Yamashina, Kyoto 607-8414, Japan.
Sato EF; Department of Biochemistry, Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, 3500-3, Minamitamagaki, Suzuka 513-8670, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 31; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Deoxyribonuclease I*/pharmacology
Deoxyribonuclease I*/metabolism
Drugs, Chinese Herbal*
Extracellular Traps*/drug effects
Extracellular Traps*/radiation effects
Ultraviolet Rays*/adverse effects
Animals ; Male ; Mice ; Calcimycin/pharmacology ; Histones/metabolism ; Hydrogen Peroxide/metabolism ; Inflammation/metabolism ; Mice, Inbred ICR ; Neutrophils/metabolism ; Protein-Arginine Deiminases/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Morphology of Neutrophils during Their Activation and NETosis: Atomic Force Microscopy Study.
Autorzy:
Sergunova V; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Research Institute of General Reanimatology, 107031 Moscow, Russia.
Inozemtsev V; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Research Institute of General Reanimatology, 107031 Moscow, Russia.; Koltzov Institute of Developmental Biology of Russian Academy of Sciences, 119334 Moscow, Russia.
Vorobjeva N; Department of Immunology, Biology Faculty, Lomonosov Moscow State University, 119234 Moscow, Russia.
Kozlova E; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Research Institute of General Reanimatology, 107031 Moscow, Russia.; Department of Medical and Biological Physics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Sherstyukova E; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Research Institute of General Reanimatology, 107031 Moscow, Russia.; Department of Medical and Biological Physics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Lyapunova S; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Research Institute of General Reanimatology, 107031 Moscow, Russia.
Chernysh A; Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Research Institute of General Reanimatology, 107031 Moscow, Russia.
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Źródło:
Cells [Cells] 2023 Sep 02; Vol. 12 (17). Date of Electronic Publication: 2023 Sep 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neutrophils*
Extracellular Traps*
Calcimycin ; Microscopy, Atomic Force ; Cell Nucleus ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Tytuł:
Stages of NETosis Development upon Stimulation of Neutrophils with Activators of Different Types.
Autorzy:
Inozemtsev V; Laboratory of Biophysics of Cell Membranes under Critical State, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Scientific Research Institute of General Reanimatology, Petrovka Street 25c2, 107031 Moscow, Russia.; Koltsov Institute of Developmental Biology, Russian Academy of Sciences, 26 Vavilov Street, 119334 Moscow, Russia.
Sergunova V; Laboratory of Biophysics of Cell Membranes under Critical State, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Scientific Research Institute of General Reanimatology, Petrovka Street 25c2, 107031 Moscow, Russia.
Vorobjeva N; Department of Immunology, Faculty of Biology, Lomonosov Moscow State University, Lenin Hills 1/12, 119234 Moscow, Russia.
Kozlova E; Laboratory of Biophysics of Cell Membranes under Critical State, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Scientific Research Institute of General Reanimatology, Petrovka Street 25c2, 107031 Moscow, Russia.; Department of Medical and Biological Physics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Sherstyukova E; Laboratory of Biophysics of Cell Membranes under Critical State, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Scientific Research Institute of General Reanimatology, Petrovka Street 25c2, 107031 Moscow, Russia.
Lyapunova S; Laboratory of Biophysics of Cell Membranes under Critical State, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Scientific Research Institute of General Reanimatology, Petrovka Street 25c2, 107031 Moscow, Russia.
Chernysh A; Laboratory of Biophysics of Cell Membranes under Critical State, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Scientific Research Institute of General Reanimatology, Petrovka Street 25c2, 107031 Moscow, Russia.; General Pathology Department, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, V.A. Negovsky Scientific Research Institute of General Reanimatology, Petrovka Street 25c2, 107031 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 02; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 02.
Typ publikacji:
Journal Article
MeSH Terms:
Neutrophils*/metabolism
Extracellular Traps*/metabolism
Calcimycin/pharmacology ; Actins/metabolism ; Chromatin/metabolism
Czasopismo naukowe
Tytuł:
Calcium ionophore improves embryonic development and pregnancy outcomes in patients with previous developmental problems in ICSI cycles.
Autorzy:
Chen X; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Jinan, 250012, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China.
Zhao H; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Jinan, 250012, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China.
Lv J; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Jinan, 250012, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China.
Dong Y; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Jinan, 250012, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China.
Zhao M; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Jinan, 250012, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China.
Sui X; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Jinan, 250012, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China.
Cui R; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, China.; Shandong Key Laboratory of Reproductive Medicine, Jinan, 250012, Shandong, China.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China.; Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China.
Liu B; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China. .; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, China. .; Shandong Key Laboratory of Reproductive Medicine, Jinan, 250012, Shandong, China. .; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China. .; Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China. .; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China. .
Wu K; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China. wukeliang_.; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, 250012, Shandong, China. wukeliang_.; Shandong Key Laboratory of Reproductive Medicine, Jinan, 250012, Shandong, China. wukeliang_.; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, 250012, Shandong, China. wukeliang_.; Shandong Technology Innovation Center for Reproductive Health, Jinan, 250012, Shandong, China. wukeliang_.; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, 250012, Shandong, China. wukeliang_.
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Źródło:
BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2022 Dec 02; Vol. 22 (1), pp. 894. Date of Electronic Publication: 2022 Dec 02.
Typ publikacji:
Journal Article
MeSH Terms:
Pregnancy Outcome*
Sperm Injections, Intracytoplasmic*
Male ; Humans ; Female ; Pregnancy ; Calcium Ionophores/pharmacology ; Calcium Ionophores/therapeutic use ; Calcimycin/pharmacology ; Calcimycin/therapeutic use ; Semen ; Embryonic Development ; Ionophores
Czasopismo naukowe
Tytuł:
Impact of calcium and reactive oxygen species on human sperm function: Role of NOX5.
Autorzy:
Keshtgar S; Department of Physiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Ghani E; Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.; Department of Physiology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
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Źródło:
Andrologia [Andrologia] 2022 Sep; Vol. 54 (8), pp. e14470. Date of Electronic Publication: 2022 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium*/metabolism
NADPH Oxidase 5*/genetics
NADPH Oxidase 5*/metabolism
Reactive Oxygen Species*/metabolism
Spermatozoa*/drug effects
Spermatozoa*/metabolism
Calcimycin/pharmacology ; Humans ; Male ; Semen/drug effects ; Semen/metabolism ; Sperm Motility/drug effects ; Sperm Motility/genetics ; Sperm Motility/physiology
Czasopismo naukowe
Tytuł:
Inhibition of platelet-activating factor (PAF)-induced platelet aggregation by fatty acids from human saliva.
Autorzy:
Smal MA; Kolling Institute of Medical Research, Royal North Shore Hospital of Sydney, St Leonards.
Baldo BA; Kolling Institute of Medical Research, Royal North Shore Hospital of Sydney, St Leonards.; Department of Medicine, University of Sydney, NSW, Australia.
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Źródło:
Platelets [Platelets] 2022 May 19; Vol. 33 (4), pp. 562-569. Date of Electronic Publication: 2021 Aug 04.
Typ publikacji:
Journal Article
MeSH Terms:
Platelet Activating Factor*/analysis
Platelet Activating Factor*/pharmacology
Platelet Aggregation*
Adenosine Diphosphate/pharmacology ; Animals ; Blood Platelets ; Calcimycin/analysis ; Calcimycin/pharmacology ; Fatty Acids/analysis ; Fatty Acids/pharmacology ; Humans ; Ionophores/analysis ; Ionophores/pharmacology ; Mammals ; Platelet Aggregation Inhibitors/pharmacology ; Saliva/chemistry ; Thrombin/pharmacology
Czasopismo naukowe
Tytuł:
The adverse impact of herbicide Roundup Ultra Plus in human spermatozoa plasma membrane is caused by its surfactant.
Autorzy:
Torres-Badia M; Research Group of Intracellular Signaling and Technology of Reproduction (SINTREP), Department of Biochemistry and Molecular Biology and Genetics, Instituto de Investigación INBIO G+C, Universidad de Extremadura, 10003, Cáceres, Spain.
Solar-Malaga S; Research Group of Intracellular Signaling and Technology of Reproduction (SINTREP), Department of Biochemistry and Molecular Biology and Genetics, Instituto de Investigación INBIO G+C, Universidad de Extremadura, 10003, Cáceres, Spain.
Serrano R; Research Group of Intracellular Signaling and Technology of Reproduction (SINTREP), Department of Biochemistry and Molecular Biology and Genetics, Instituto de Investigación INBIO G+C, Universidad de Extremadura, 10003, Cáceres, Spain.
Garcia-Marin LJ; Research Group of Intracellular Signaling and Technology of Reproduction (SINTREP), Department of Biochemistry and Molecular Biology and Genetics, Instituto de Investigación INBIO G+C, Universidad de Extremadura, 10003, Cáceres, Spain.
Bragado MJ; Research Group of Intracellular Signaling and Technology of Reproduction (SINTREP), Department of Biochemistry and Molecular Biology and Genetics, Instituto de Investigación INBIO G+C, Universidad de Extremadura, 10003, Cáceres, Spain. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jul 29; Vol. 12 (1), pp. 13082. Date of Electronic Publication: 2022 Jul 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Herbicides*/metabolism
Herbicides*/toxicity
Sperm Motility*
Calcimycin/pharmacology ; Cell Membrane ; Glycogen Synthase Kinase 3/metabolism ; Humans ; Lipids/pharmacology ; Male ; Semen ; Spermatozoa/metabolism ; Surface-Active Agents/metabolism ; Surface-Active Agents/toxicity
Czasopismo naukowe
Tytuł:
Evaluation of the novel vaginal contraceptive agent PPCM in preclinical studies using sperm hyaluronan binding and acrosome status assays.
Autorzy:
North BB; Yaso Therapeutics Inc., Frisco, Texas, USA.
Weitzel MB; Yaso Therapeutics Inc., Frisco, Texas, USA.
Waller DP; Yaso Therapeutics Inc., Frisco, Texas, USA.; College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA.
Birch WX; Department of Urology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
Feathergill KA; College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA.
Birch LA; Department of Urology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
De Jonge CJ; Department of Urology, University of Minnesota Medical Center, Minneapolis, Minnesota, USA.
Prins GS; Department of Urology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
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Źródło:
Andrology [Andrology] 2022 Feb; Vol. 10 (2), pp. 367-376. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Acrosome/*drug effects
Contraceptive Agents/*pharmacology
Polymers/*pharmacology
Spermatozoa/*drug effects
Vaginal Creams, Foams, and Jellies/*pharmacology
Calcimycin/pharmacology ; Female ; Humans ; Hyaluronic Acid ; Male ; Pregnancy ; Semen/drug effects ; Sperm Motility/drug effects
Czasopismo naukowe
Tytuł:
A Central Role for TRPM4 in Ca -Signal Amplification and Vasoconstriction.
Autorzy:
Csípő T; Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; Doctoral School of Kálmán Laki, University of Debrecen, 4032 Debrecen, Hungary.
Czikora Á; Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Fülöp GÁ; Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; Doctoral School of Kálmán Laki, University of Debrecen, 4032 Debrecen, Hungary.
Gulyás H; Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; Doctoral School of Pharmaceutical Sciences, University of Debrecen, 4032 Debrecen, Hungary.
Rutkai I; Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Tóth EP; Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Pórszász R; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Szalai A; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Bölcskei K; Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 7624 Pécs, Hungary.; Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Helyes Z; Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 7624 Pécs, Hungary.; Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Pintér E; Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 7624 Pécs, Hungary.; Szentágothai Research Centre, University of Pécs, 7624 Pécs, Hungary.
Papp Z; Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; HAS-UD Vascular Biology and Myocardial Pathophysiology Research Group, Hungarian Academy of Sciences, 4032 Debrecen, Hungary.
Ungvári Z; Vascular Cognitive Impairment and Neurodegeneration Program, Oklahoma Center for Geroscience, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.; International Training Program in Geroscience, Department of Public Health, Semmelweis University, 1089 Budapest, Hungary.; The Peggy and Charles Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.; Department of Health Promotion Sciences, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Tóth A; Division of Clinical Physiology, Department of Cardiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.; HAS-UD Vascular Biology and Myocardial Pathophysiology Research Group, Hungarian Academy of Sciences, 4032 Debrecen, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 27; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 27.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium Signaling*/drug effects
Vasoconstriction*/drug effects
TRPM Cation Channels/*metabolism
Administration, Intravenous ; Animals ; Arteries/drug effects ; Blood Pressure/drug effects ; Calcimycin/pharmacology ; Calcium/metabolism ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/physiology ; Heart Rate/drug effects ; Ionophores/pharmacology ; Male ; Muscle Development/drug effects ; Muscle, Skeletal/blood supply ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Norepinephrine/pharmacology ; Phenanthrenes/administration & dosage ; Phenanthrenes/pharmacology ; Potassium Chloride/pharmacology ; Rats, Wistar ; TRPM Cation Channels/agonists ; Rats
Czasopismo naukowe
Tytuł:
Anti-Allergic and Anti-Inflammatory Effects of Neferine on RBL-2H3 Cells.
Autorzy:
Chiu KM; Division of Cardiovascular Surgery, Cardiovascular Center, Far-Eastern Memorial Hospital, New Taipei City 22060, Taiwan.; Department of Nursing, Oriental Institute of Technology, New Taipei City 22060, Taiwan.; Department of Photonics Engineering, Yuan Ze University, Taoyuan 32003, Taiwan.
Hung YL; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 24205, Taiwan.; Graduate Institute, Department of Pharmacology, National Taiwan University College of Medicine, Taipei 10051, Taiwan.
Wang SJ; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 24205, Taiwan.; School of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Tsai YJ; School of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Wu NL; Department of Dermatology, MacKay Memorial Hospital, Taipei 104217, Taiwan.; Department of Medicine, Mackay Medical College, New Taipei City 25245, Taiwan.; Mackay Junior College of Medicine, Nursing, and Management, New Taipei City 25245, Taiwan.
Liang CW; School of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.
Chang DC; Department of Mathematics and Statistics, Department of Computer Science, Georgetown University, Washington, DC 20057, USA.
Hung CF; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 24205, Taiwan.; School of Medicine, Fu Jen Catholic University, New Taipei City 24205, Taiwan.; School of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 12; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 12.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Allergic Agents/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Benzylisoquinolines/*pharmacology
Mast Cells/*drug effects
Animals ; Anti-Allergic Agents/therapeutic use ; Benzylisoquinolines/therapeutic use ; Calcimycin/pharmacology ; Calcium/metabolism ; Cell Line ; Cell Movement/drug effects ; Cytokines/genetics ; Cytokines/metabolism ; Dermatitis, Atopic/chemically induced ; Dermatitis, Atopic/drug therapy ; Dermatitis, Atopic/pathology ; Dinitrochlorobenzene/pharmacology ; Disease Models, Animal ; Mast Cells/cytology ; Mast Cells/metabolism ; Mice ; Mice, Inbred BALB C ; Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Phosphorylation/drug effects ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
Factors affecting intracellular calcium influx in response to calcium ionophore A23187 in equine sperm.
Autorzy:
Sampaio B; College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Ortiz I; College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Resende H; College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Felix M; College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Varner D; College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Hinrichs K; College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, TX, USA.
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Źródło:
Andrology [Andrology] 2021 Sep; Vol. 9 (5), pp. 1631-1651. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcimycin/*pharmacology
Calcium/*metabolism
Calcium Ionophores/*pharmacology
Serum Albumin, Bovine/*metabolism
Spermatozoa/*drug effects
Animals ; Horses ; Male ; Mice
Czasopismo naukowe
Tytuł:
A Novel Allyl Transfer Coupled with a Grob Fragmentation.
Autorzy:
Li SG; State Key Laboratory of Bioorganic and Natural Products Chemistry, Collaborative Innovation Center of Chemistry for Life Sciences, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
Chen HJ; State Key Laboratory of Bioorganic and Natural Products Chemistry, Collaborative Innovation Center of Chemistry for Life Sciences, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
Yang YY; State Key Laboratory of Bioorganic and Natural Products Chemistry, Collaborative Innovation Center of Chemistry for Life Sciences, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
Wu WJ; State Key Laboratory of Bioorganic and Natural Products Chemistry, Collaborative Innovation Center of Chemistry for Life Sciences, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
Wu Y; State Key Laboratory of Bioorganic and Natural Products Chemistry, Collaborative Innovation Center of Chemistry for Life Sciences, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China. .
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Źródło:
Chemistry, an Asian journal [Chem Asian J] 2015 Nov; Vol. 10 (11), pp. 2333-6. Date of Electronic Publication: 2015 Aug 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcimycin/*analogs & derivatives
Acetates/chemistry ; Calcimycin/chemical synthesis ; Calcimycin/chemistry ; Diphosphonates/chemistry ; Hydrogen Peroxide/chemistry ; Polyketides/chemistry ; Stereoisomerism
Czasopismo naukowe
Tytuł:
In vivo and in vitro anti‑allergic and anti‑inflammatory effects of Dryopteris crassirhizoma through the modulation of the NF‑ĸB signaling pathway in an ovalbumin‑induced allergic asthma mouse model.
Autorzy:
Piao CH; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
Bui TT; Faculty of Biology and Environmental Science, University of Science and Education, The University of Danang, Danang 555940, Vietnam.
Fan YJ; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
Nguyen TV; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
Shin DU; Food Biotechnology Program, Korea University of Science and Technology, Daejeon 305‑350, Republic of Korea.
Song CH; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
Lee SY; Food Biotechnology Program, Korea University of Science and Technology, Daejeon 305‑350, Republic of Korea.
Shin HS; Food Biotechnology Program, Korea University of Science and Technology, Daejeon 305‑350, Republic of Korea.
Kim HT; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
Chai OH; Department of Anatomy, Jeonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2020 Nov; Vol. 22 (5), pp. 3597-3606. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Allergic Agents/*administration & dosage
Anti-Inflammatory Agents/*administration & dosage
Asthma/*chemically induced
Asthma/*drug therapy
Dryopteris/*chemistry
NF-kappa B/*metabolism
Phytotherapy/*methods
Plant Extracts/*administration & dosage
Signal Transduction/*drug effects
Animals ; Asthma/metabolism ; Bronchoalveolar Lavage Fluid ; Calcimycin/pharmacology ; Cell Line, Tumor ; Cytokines/metabolism ; Disease Models, Animal ; Humans ; Lung/pathology ; Male ; Mast Cells/drug effects ; Mast Cells/metabolism ; Mice ; Mice, Inbred BALB C ; Ovalbumin/adverse effects ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Tytuł:
Calcium Ionophore-Induced Extracellular Vesicles Mediate Cytoprotection against Simulated Ischemia/Reperfusion Injury in Cardiomyocyte-Derived Cell Lines by Inducing Heme Oxygenase 1.
Autorzy:
Pečan P; National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.; Graduate School of Biomedicine, Faculty of Medicine, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Hambalkó S; Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1085 Budapest, Hungary.
Ha VT; National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.; Graduate School of Biomedicine, Faculty of Medicine, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Nagy CT; Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1085 Budapest, Hungary.
Pelyhe C; Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1085 Budapest, Hungary.
Lainšček D; National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.; Centre of Excelence EN-FIST, SI-1000 Ljubljana, Slovenia.
Kenyeres B; Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1085 Budapest, Hungary.
Brenner GB; Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1085 Budapest, Hungary.
Görbe A; Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1085 Budapest, Hungary.; Pharmahungary Group, 6722 Szeged, Hungary.
Kittel Á; Institute of Experimental Medicine, ELRN, 1083 Budapest, Hungary.
Barteková M; Centre of Experimental Medicine, Institute for Heart Research, Slovak Academy of Sciences, 84104 Bratislava, Slovakia.; Institute of Physiology, Faculty of Medicine, Comenius University in Bratislava, 81372 Bratislava, Slovakia.
Ferdinandy P; Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1085 Budapest, Hungary.; Pharmahungary Group, 6722 Szeged, Hungary.
Manček-Keber M; National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.; Centre of Excelence EN-FIST, SI-1000 Ljubljana, Slovenia.
Giricz Z; Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1085 Budapest, Hungary.; Pharmahungary Group, 6722 Szeged, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Oct 16; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 16.
Typ publikacji:
Journal Article
MeSH Terms:
Exosomes/*metabolism
Heme Oxygenase-1/*metabolism
Myocardial Reperfusion Injury/*metabolism
Myocytes, Cardiac/*metabolism
Animals ; Calcimycin/pharmacology ; Calcium Ionophores/pharmacology ; Cell Death ; Exosomes/drug effects ; HEK293 Cells ; Heme Oxygenase-1/genetics ; Humans ; Mice ; Rats ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism
Czasopismo naukowe
Tytuł:
Determining the effect of calcium on cell death rate and perforation formation during leaf development in the novel model system, the lace plant (Aponogeton madagascariensis).
Autorzy:
Fraser MS; Department of Biology, Dalhousie University, Halifax, Canada.
Dauphinee AN; Department of Biology, Dalhousie University, Halifax, Canada.; Current address: Department of Molecular Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Gunawardena AHLAN; Department of Biology, Dalhousie University, Halifax, Canada.
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Źródło:
Journal of microscopy [J Microsc] 2020 Jun; Vol. 278 (3), pp. 132-144. Date of Electronic Publication: 2020 Jan 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alismatales/*growth & development
Apoptosis/*drug effects
Calcium/*metabolism
Calcium Ionophores/*pharmacology
Cell Death/*drug effects
Plant Leaves/*growth & development
Alismatales/cytology ; Alismatales/drug effects ; Calcimycin/pharmacology ; Cell Tracking ; Image Processing, Computer-Assisted ; Lanthanum/pharmacology ; Optical Imaging ; Plant Leaves/drug effects ; Ruthenium Red/pharmacology
Czasopismo naukowe
Tytuł:
Use of Thrombodynamics for revealing the participation of platelet, erythrocyte, endothelial, and monocyte microparticles in coagulation activation and propagation.
Autorzy:
Lipets EN; Department of Biophysics, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.; Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russian Federation.
Antonova OA; Institute of Experimental Cardiology, National Medical Research Center for Cardiology, Russian Ministry of Health, Moscow, Russian Federation.
Shustova ON; Institute of Experimental Cardiology, National Medical Research Center for Cardiology, Russian Ministry of Health, Moscow, Russian Federation.
Losenkova KV; Medicity Research Laboratory, University of Turku, Turku, Finland.
Mazurov AV; Institute of Experimental Cardiology, National Medical Research Center for Cardiology, Russian Ministry of Health, Moscow, Russian Federation.
Ataullakhanov FI; Department of Biophysics, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russian Federation.; Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, Russian Federation.; Faculty of Physics, Lomonosov Moscow State University, Moscow, Russian Federation.; Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russian Federation.
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Źródło:
PloS one [PLoS One] 2020 May 29; Vol. 15 (5), pp. e0227932. Date of Electronic Publication: 2020 May 29 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Coagulation/*drug effects
Cell-Derived Microparticles/*drug effects
Thrombin/*metabolism
Thrombosis/*blood
Blood Platelets/drug effects ; Calcimycin/pharmacology ; Calcium/metabolism ; Cell-Derived Microparticles/metabolism ; Endothelial Cells/drug effects ; Erythrocytes/drug effects ; Flow Cytometry ; Human Umbilical Vein Endothelial Cells ; Humans ; Monocytes/drug effects ; Peptide Fragments/pharmacology ; Thrombosis/drug therapy ; Thrombosis/pathology
Czasopismo naukowe
Tytuł:
Synthesis and absolute configuration of demethyl (C-11) cezomycin.
Autorzy:
Li SG; State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institution of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032 (China).
Wu Y
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Źródło:
Chemistry, an Asian journal [Chem Asian J] 2013 Nov; Vol. 8 (11), pp. 2792-800. Date of Electronic Publication: 2013 Jul 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Bacterial Agents/*chemical synthesis
Calcimycin/*analogs & derivatives
Anti-Bacterial Agents/chemistry ; Calcimycin/chemical synthesis ; Calcimycin/chemistry ; Hydrogen/chemistry ; Oxidation-Reduction ; Stereoisomerism
Czasopismo naukowe
Tytuł:
The Cytosolic Phospholipase A 2 α N-terminal C2 Domain Binds and Oligomerizes on Membranes with Positive Curvature.
Autorzy:
Ward KE; Department of Chemistry and Biochemistry, University of Notre Dame, South Bend, IN 46556, USA.
Sengupta R; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47906, USA.
Ropa JP; Department of Chemistry and Biochemistry, University of Notre Dame, South Bend, IN 46556, USA.
Amiar S; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47906, USA.
Stahelin RV; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47906, USA.; Purdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.
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Źródło:
Biomolecules [Biomolecules] 2020 Apr 22; Vol. 10 (4). Date of Electronic Publication: 2020 Apr 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
C2 Domains*
Protein Multimerization*
Cell Membrane/*metabolism
Group IV Phospholipases A2/*chemistry
Group IV Phospholipases A2/*metabolism
A549 Cells ; Calcimycin/pharmacology ; Cell Membrane/ultrastructure ; Cholesterol/metabolism ; Cytosol/enzymology ; Golgi Apparatus/metabolism ; Group IV Phospholipases A2/ultrastructure ; HeLa Cells ; Humans ; Lipid Droplets/chemistry ; Lipids/chemistry ; Protein Binding ; Protein Domains
Czasopismo naukowe

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