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Wyszukujesz frazę ""Calcitonin"" wg kryterium: Temat


Starter badań:

Tytuł:
Pharmacologic characterization of atogepant: A potent and selective calcitonin gene-related peptide receptor antagonist.
Autorzy:
Moore E; Merck & Co., Inc., Rahway, NJ, USA.
Bell IM; Merck & Co., Inc., Rahway, NJ, USA.
Fraley ME; Merck & Co., Inc., Rahway, NJ, USA.
Burgey CS; Merck & Co., Inc., Rahway, NJ, USA.
White RB; Merck & Co., Inc., Rahway, NJ, USA.
Li CC; Merck & Co., Inc., Rahway, NJ, USA.
Regan CP; Merck & Co., Inc., Rahway, NJ, USA.
Danziger A; Merck & Co., Inc., Rahway, NJ, USA.
McGaraughty SP; AbbVie, North Chicago, IL, USA.
Naseri Kouzehgarani G; AbbVie, North Chicago, IL, USA.
Salvatore C; Merck & Co., Inc., Rahway, NJ, USA.
Banerjee P; AbbVie, Madison, NJ, USA.
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Źródło:
Cephalalgia : an international journal of headache [Cephalalgia] 2024 Jan; Vol. 44 (1), pp. 3331024231226186.
Typ publikacji:
Journal Article
MeSH Terms:
Calcitonin Gene-Related Peptide*/metabolism
Receptors, Calcitonin Gene-Related Peptide*/metabolism
Piperidines*
Pyridines*
Pyrroles*
Spiro Compounds*
Humans ; Rats ; Animals ; Calcitonin Gene-Related Peptide Receptor Antagonists/pharmacology ; Calcitonin Gene-Related Peptide Receptor Antagonists/therapeutic use ; Hyperalgesia/drug therapy
Czasopismo naukowe
Tytuł:
Efficacy and safety of monoclonal antibodies targeting CGRP in migraine prevention. GRADE tables elaborated by the ad hoc working group of the International Headache Society.
Autorzy:
Aleksovska K; Department of Neurology, Ss. Cyril and Methodius University, Skopje, Macedonia.
Hershey AD; Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, USA.
Deen M; Department of Neurology, Danish Headache Center, Rigshospitalet - Glostrup, Glostrup, Denmark.
Icco R; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.; Headache Science & Neurorehabilitation Center, IRCCS Mondino Foundation, Pavia, Italy.
Lee MJ; Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.
Diener HC; Department of Neuroepidemiology, University Duisburg-Essen, Essen, Germany.
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Źródło:
Cephalalgia : an international journal of headache [Cephalalgia] 2023 Oct; Vol. 43 (10), pp. 3331024231206162.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Calcitonin Gene-Related Peptide*
Migraine Disorders*/drug therapy
Migraine Disorders*/prevention & control
Migraine Disorders*/chemically induced
Humans ; Antibodies, Monoclonal/adverse effects ; Antibodies, Monoclonal/therapeutic use ; Headache/drug therapy ; Receptors, Calcitonin Gene-Related Peptide/therapeutic use
Czasopismo naukowe
Tytuł:
Effectiveness of three calcitonin gene-related peptide monoclonal antibodies for migraine: A 12-month, single-center, observational real-world study in Japan.
Autorzy:
Suzuki K; Department of Neurology, Dokkyo Medical University, Mibu, Japan.
Suzuki S; Department of Neurology, Dokkyo Medical University, Mibu, Japan.
Shiina T; Department of Neurology, Dokkyo Medical University, Mibu, Japan.
Tatsumoto M; Medical Safety Management Center, Dokkyo Medical University Hospital, Mibu, Japan.
Fujita H; Department of Neurology, Dokkyo Medical University, Mibu, Japan.
Haruyama Y; Integrated Research Faculty for Advanced Medical Sciences, Dokkyo Medical University, Mibu, Japan.
Hirata K; Department of Neurology, Dokkyo Medical University, Mibu, Japan.
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Źródło:
Cephalalgia : an international journal of headache [Cephalalgia] 2023 May; Vol. 43 (5), pp. 3331024231177649.
Typ publikacji:
Journal Article
MeSH Terms:
Calcitonin Gene-Related Peptide*
Migraine Disorders*/prevention & control
Humans ; Adult ; Middle Aged ; Japan ; Antibodies, Monoclonal ; Calcitonin Gene-Related Peptide Receptor Antagonists/therapeutic use
Czasopismo naukowe
Tytuł:
Evaluating the efficacy of CGRP mAbs and gepants for the preventive treatment of migraine: A systematic review and network meta-analysis of phase 3 randomised controlled trials.
Autorzy:
Haghdoost F; The George Institute for Global Health, University of New South Wales, Sydney, Australia.
Puledda F; Headache Group, Wolfson CARD, SLaM Biomedical Research Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, National Institute for Health Research-Wellcome Trust King's Clinical Research Facility, King's College Hospital, London, United Kingdom.
Garcia-Azorin D; Headache Unit, Department of Neurology, Hospital Clínico Universitario de Valladolid, Gerencia Regional de Salud de Castilla y Leon, Valladolid, Spain.
Huessler EM; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Germany.
Messina R; Neuroimaging Research Unit and Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Pozo-Rosich P; Headache Unit and Headache and Neurological Pain Research Group, Neurology Department, Hospital Universitari Vall d'Hebron and VHIR, Barcelona, Spain.
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Źródło:
Cephalalgia : an international journal of headache [Cephalalgia] 2023 Apr; Vol. 43 (4), pp. 3331024231159366.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article; Review
MeSH Terms:
Calcitonin Gene-Related Peptide*
Migraine Disorders*/drug therapy
Migraine Disorders*/prevention & control
Humans ; Calcitonin Gene-Related Peptide Receptor Antagonists/therapeutic use ; Network Meta-Analysis ; Headache ; Randomized Controlled Trials as Topic
Czasopismo naukowe
Tytuł:
Alopecia as an emerging adverse event to CGRP monoclonal antibodies: Cases Series, evaluation of FAERS, and literature review.
Autorzy:
Ruiz M; Department of Biological Sciences, Florida International University, Miami, Florida, USA.
Cocores A; Department of Neurology, Division of Headache, University of Miami Miller School of Medicine, Miami, Florida, USA.
Tosti A; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.
Goadsby PJ; Institute of Psychiatry, Psychology, And Neuroscience, King's College, London, UK.; Department of Neurology, University of California, Los Angeles, California, USA.
Monteith TS; Department of Neurology, Division of Headache, University of Miami Miller School of Medicine, Miami, Florida, USA.
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Źródło:
Cephalalgia : an international journal of headache [Cephalalgia] 2023 Feb; Vol. 43 (2), pp. 3331024221143538.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Calcitonin Gene-Related Peptide*
Migraine Disorders*
Female ; Humans ; Antibodies, Monoclonal ; Calcitonin Gene-Related Peptide Receptor Antagonists ; Receptors, Calcitonin Gene-Related Peptide ; Male
Czasopismo naukowe
Tytuł:
Open-label trials for CGRP-targeted drugs in migraine prevention: A narrative review.
Autorzy:
Raffaelli B; Department of Neurology, Charité Universitätsmedizin Berlin, Berlin, Germany.; Clinician Scientist Program, Berlin Institute of Health, Berlin, Germany.
De Icco R; Headache Science & Neurorehabilitation Center, IRCCS Mondino Foundation, Pavia, Italy.; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Corrado M; Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Terhart M; Department of Neurology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Ailani J; MedStar Georgetown University Hospital, Washington, DC, USA.
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Źródło:
Cephalalgia : an international journal of headache [Cephalalgia] 2023 Feb; Vol. 43 (2), pp. 3331024221137091.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Calcitonin Gene-Related Peptide Receptor Antagonists*/therapeutic use
Migraine Disorders*/drug therapy
Migraine Disorders*/prevention & control
Humans ; Calcitonin Gene-Related Peptide ; Quality of Life ; Randomized Controlled Trials as Topic ; Receptors, Calcitonin Gene-Related Peptide
Czasopismo naukowe
Tytuł:
Safety and tolerability of monoclonal antibodies targeting the CGRP pathway and gepants in migraine prevention: A systematic review and network meta-analysis.
Autorzy:
Messina R; Neuroimaging Research Unit and Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.
Huessler EM; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Germany.
Puledda F; Headache Group, Wolfson CARD, SLaM Biomedical Research Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, National Institute for Health Research (NIHR)-Wellcome Trust King's Clinical Research Facility, King's College Hospital, London, United Kingdom.
Haghdoost F; The George Institute for Global Health, University of New South Wales (UNSW), Sydney, Australia.
Lebedeva ER; Department of Neurology, the Ural State Medical University, Yekaterinburg, Russia.; International Headache Centre 'Europe-Asia', Yekaterinburg, Russia.
Diener HC; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Germany.
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Źródło:
Cephalalgia : an international journal of headache [Cephalalgia] 2023 Mar; Vol. 43 (3), pp. 3331024231152169.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article; Review
MeSH Terms:
Calcitonin Gene-Related Peptide*/metabolism
Migraine Disorders*/drug therapy
Migraine Disorders*/prevention & control
Migraine Disorders*/chemically induced
Humans ; Calcitonin Gene-Related Peptide Receptor Antagonists/adverse effects ; Network Meta-Analysis ; Antibodies, Monoclonal/adverse effects
Czasopismo naukowe
Tytuł:
s -Coupled CGRP Receptor Signaling Axis from the Trigeminal Ganglion Neuron to Odontoblast Negatively Regulates Dentin Mineralization.
Autorzy:
Saito N; Department of Physiology, Tokyo Dental College, 2-9-18, Kanda-Misaki-cho, Chiyoda-ku, Tokyo 101-0061, Japan.; Department of Dental Anesthesiology, Tokyo Dental College, 2-9-18, Kanda-Misaki-cho, Chiyoda-ku, Tokyo 101-0061, Japan.
Kimura M; Department of Physiology, Tokyo Dental College, 2-9-18, Kanda-Misaki-cho, Chiyoda-ku, Tokyo 101-0061, Japan.
Ouchi T; Department of Physiology, Tokyo Dental College, 2-9-18, Kanda-Misaki-cho, Chiyoda-ku, Tokyo 101-0061, Japan.
Ichinohe T; Department of Dental Anesthesiology, Tokyo Dental College, 2-9-18, Kanda-Misaki-cho, Chiyoda-ku, Tokyo 101-0061, Japan.
Shibukawa Y; Department of Physiology, Tokyo Dental College, 2-9-18, Kanda-Misaki-cho, Chiyoda-ku, Tokyo 101-0061, Japan.
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Źródło:
Biomolecules [Biomolecules] 2022 Nov 24; Vol. 12 (12). Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Calcitonin Gene-Related Peptide*/metabolism
Trigeminal Ganglion*
Calcitonin Gene-Related Peptide/pharmacology ; Odontoblasts ; Calcitonin Gene-Related Peptide Receptor Antagonists/metabolism ; Calcitonin Gene-Related Peptide Receptor Antagonists/pharmacology ; Neurons/metabolism ; Signal Transduction ; Cyclic AMP/metabolism ; Dentin
Czasopismo naukowe
Tytuł:
Elucidating the Ability of CGRP to Modulate Microvascular Events in Mouse Skin.
Autorzy:
Zarban AA; Section of Vascular Biology and Inflammation, School of Cardiovascular and Metabolic Medicine & Sciences, BHF Centre of Research Excellence, Franklin-Wilkins Building, Waterloo Campus, King's College London, London SE1 9NH, UK.; Department of Pharmacology and Toxicology, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.
Chaudhry H; Section of Vascular Biology and Inflammation, School of Cardiovascular and Metabolic Medicine & Sciences, BHF Centre of Research Excellence, Franklin-Wilkins Building, Waterloo Campus, King's College London, London SE1 9NH, UK.
de Sousa Valente J; Section of Vascular Biology and Inflammation, School of Cardiovascular and Metabolic Medicine & Sciences, BHF Centre of Research Excellence, Franklin-Wilkins Building, Waterloo Campus, King's College London, London SE1 9NH, UK.
Argunhan F; Section of Vascular Biology and Inflammation, School of Cardiovascular and Metabolic Medicine & Sciences, BHF Centre of Research Excellence, Franklin-Wilkins Building, Waterloo Campus, King's College London, London SE1 9NH, UK.
Ghanim H; Section of Vascular Biology and Inflammation, School of Cardiovascular and Metabolic Medicine & Sciences, BHF Centre of Research Excellence, Franklin-Wilkins Building, Waterloo Campus, King's College London, London SE1 9NH, UK.
Brain SD; Section of Vascular Biology and Inflammation, School of Cardiovascular and Metabolic Medicine & Sciences, BHF Centre of Research Excellence, Franklin-Wilkins Building, Waterloo Campus, King's College London, London SE1 9NH, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 13; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Calcitonin Gene-Related Peptide*/genetics
Calcitonin Gene-Related Peptide*/pharmacology
Neuropeptides*/pharmacology
Mice ; Animals ; Tumor Necrosis Factor-alpha/pharmacology ; Substance P/adverse effects ; Calcitonin Gene-Related Peptide Receptor Antagonists/pharmacology ; Carrageenan/adverse effects ; Edema/chemically induced ; Edema/pathology ; Inflammation/pathology ; Skin/pathology ; Vasodilator Agents/pharmacology ; Mice, Knockout
Czasopismo naukowe
Tytuł:
Transcript-dependent effects of the CALCA gene on the progression of post-traumatic osteoarthritis in mice.
Autorzy:
Jiang S; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Xie W; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Knapstein PR; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Donat A; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Albertsen LC; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sevecke J; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Erdmann C; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Appelt J; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany.
Fuchs M; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany.
Hildebrandt A; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany.; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Center for Musculoskeletal Surgery, Berlin, Germany.
Maleitzke T; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Julius Wolff Institute, Berlin, Germany.; Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Center for Musculoskeletal Surgery, Berlin, Germany.; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, BIH Charité Clinician Scientist Program, Berlin, Germany.; Department of Orthopaedic Surgery, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Frosch KH; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Department of Trauma Surgery, Orthopedics and Sports Traumatology, BG Hospital Hamburg, Hamburg, Germany.
Baranowsky A; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Keller J; Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. .
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Źródło:
Communications biology [Commun Biol] 2024 Feb 23; Vol. 7 (1), pp. 223. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:
Journal Article
MeSH Terms:
Osteoarthritis*/genetics
Osteoarthritis*/metabolism
Osteophyte*
Calcitonin Gene-Related Peptide*/genetics
Calcitonin Gene-Related Peptide*/metabolism
Animals ; Mice ; Disease Models, Animal ; Knee Joint/pathology ; Osteoclasts/metabolism
Czasopismo naukowe

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