Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Calcium Channels"" wg kryterium: Temat


Tytuł :
Clinical and molecular spectrum of P/Q type calcium channel Cav2.1 in epileptic patients.
Autorzy :
Alehabib E; Student Research Committee, Department of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Esmaeilizadeh Z; Department of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ranji-Burachaloo S; Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Tafakhori A; Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Darvish H; Neuroscience Research Center, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Movafagh A; Department of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. .
Pokaż więcej
Źródło :
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2021 Nov 02; Vol. 16 (1), pp. 461. Date of Electronic Publication: 2021 Nov 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels, Q-Type*
Epilepsy*/genetics
Calcium Channels/*genetics
Adolescent ; Calcium Channels, N-Type/genetics ; Humans ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Defects in the STIM1 SOARα2 domain affect multiple steps in the CRAC channel activation cascade.
Autorzy :
Höglinger C; Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020, Linz, Austria.
Grabmayr H; Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020, Linz, Austria.
Maltan L; Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020, Linz, Austria.
Horvath F; Institute of Theoretical Physics, Johannes Kepler University Linz, Altenbergerstraße 69, 4040, Linz, Austria.
Krobath H; Institute of Theoretical Physics, Johannes Kepler University Linz, Altenbergerstraße 69, 4040, Linz, Austria.
Muik M; Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020, Linz, Austria.
Tiffner A; Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020, Linz, Austria.
Renger T; Institute of Theoretical Physics, Johannes Kepler University Linz, Altenbergerstraße 69, 4040, Linz, Austria.
Romanin C; Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020, Linz, Austria.
Fahrner M; Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020, Linz, Austria. .
Derler I; Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020, Linz, Austria. .
Pokaż więcej
Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Oct; Vol. 78 (19-20), pp. 6645-6667. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Release Activated Calcium Channels/*genetics
Neoplasm Proteins/*genetics
Stromal Interaction Molecule 1/*genetics
Calcium/metabolism ; Calcium Channels/genetics ; Cell Line ; Cell Membrane/genetics ; Endoplasmic Reticulum/genetics ; HEK293 Cells ; Humans ; Membrane Proteins/genetics ; Point Mutation/genetics
Czasopismo naukowe
Tytuł :
Rab11-dependent recycling of calcium channels is mediated by auxiliary subunit α 2 δ-1 but not α 2 δ-3.
Autorzy :
Meyer JO; Department of Neuroscience, Physiology and Pharmacology, University College London, Gower Street, London, WC1E 6BT, UK.
Dolphin AC; Department of Neuroscience, Physiology and Pharmacology, University College London, Gower Street, London, WC1E 6BT, UK. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2021 May 13; Vol. 11 (1), pp. 10256. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels/*metabolism
Calcium Channels, L-Type/*metabolism
rab GTP-Binding Proteins/*metabolism
Animals ; Brain/metabolism ; Calcium/metabolism ; Calcium Channels/genetics ; Calcium Channels/physiology ; Calcium Channels, L-Type/genetics ; Calcium Channels, N-Type/genetics ; Calcium Channels, N-Type/metabolism ; Cell Line ; Cell Membrane/metabolism ; Cyclohexanecarboxylic Acids/metabolism ; Gabapentin/metabolism ; Hippocampus/metabolism ; Neurites/metabolism ; Neurons/metabolism ; Presynaptic Terminals/metabolism ; Primary Cell Culture ; Protein Transport ; Rats ; gamma-Aminobutyric Acid/metabolism ; rab GTP-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
CACNA1H Calcium Channel Mutations in Primary Aldosteronism - Is Sodium the Culprit?
Autorzy :
Stölting G; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Nephrology and Medical Intensive Care, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, BIH Center for Regenerative Therapies, Berlin, Germany.
Scholl UI; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Nephrology and Medical Intensive Care, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany.; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, BIH Center for Regenerative Therapies, Berlin, Germany.
Pokaż więcej
Źródło :
Endocrinology [Endocrinology] 2020 Dec 01; Vol. 161 (12).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Calcium Channels, T-Type*/genetics
Hyperaldosteronism*/genetics
Aldosterone ; Calcium/metabolism ; Calcium Channels ; Humans ; Mutation ; Sodium
Czasopismo naukowe
Tytuł :
Ion-pair interactions between voltage-sensing domain IV and pore domain I regulate Ca V 1.1 gating.
Autorzy :
El Ghaleb Y; Department of Physiology and Medical Physics, Institute of Physiology, Medical University Innsbruck, Innsbruck, Austria.
Fernández-Quintero ML; Department of Physiology and Medical Physics, Institute of Physiology, Medical University Innsbruck, Innsbruck, Austria; Department of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck.
Monteleone S; Department of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck; Evotec (UK) Ltd., Abingdon, Oxfordshire, United Kingdom.
Tuluc P; Department of Pharmacology and Toxicology, Institute of Pharmacy and Center for Molecular Biosciences, University of Innsbruck, Innsbruck, Austria.
Campiglio M; Department of Physiology and Medical Physics, Institute of Physiology, Medical University Innsbruck, Innsbruck, Austria.
Liedl KR; Department of General, Inorganic and Theoretical Chemistry, and Center for Molecular Biosciences Innsbruck.
Flucher BE; Department of Physiology and Medical Physics, Institute of Physiology, Medical University Innsbruck, Innsbruck, Austria. Electronic address: .
Pokaż więcej
Źródło :
Biophysical journal [Biophys J] 2021 Oct 19; Vol. 120 (20), pp. 4429-4441. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels, L-Type*/genetics
Calcium Channels, L-Type*/metabolism
Ion Channel Gating*
Cations ; Patch-Clamp Techniques
Czasopismo naukowe
Tytuł :
The mechanism of complex formation between calmodulin and voltage gated calcium channels revealed by molecular dynamics.
Autorzy :
Yaduvanshi S; Amity Institute of Molecular Medicine and Stem Cell Research (AIMMSCR), Amity University Noida, Noida, Uttar Pradesh, India.
Ero R; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Kumar V; Amity Institute of Molecular Medicine and Stem Cell Research (AIMMSCR), Amity University Noida, Noida, Uttar Pradesh, India.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2021 Oct 05; Vol. 16 (10), pp. e0258112. Date of Electronic Publication: 2021 Oct 05 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels*/chemistry
Calcium Channels*/metabolism
Calmodulin*/chemistry
Calmodulin*/metabolism
Molecular Dynamics Simulation*
Calcium/*metabolism
Binding Sites ; Protein Binding ; Protein Conformation
Czasopismo naukowe
Tytuł :
A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii.
Autorzy :
Li ZH; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, 30602, USA.
King TP; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, 30602, USA.
Ayong L; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, 30602, USA.
Asady B; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Heath, Baltimore, MD, 21205, USA.
Cai X; Division of Cardiology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Rahman T; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, USA.
Vella SA; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, 30602, USA.
Coppens I; Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Heath, Baltimore, MD, 21205, USA.
Patel S; Department of Cell and Developmental Biology, University College London, London, WC1E 6BT, UK.
Moreno SNJ; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, 30602, USA. .; Department of Cellular Biology, University of Georgia, Athens, GA, 30602, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Oct 04; Vol. 12 (1), pp. 5802. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels/*metabolism
Protozoan Proteins/*metabolism
Toxoplasma/*growth & development
Toxoplasma/*metabolism
Amino Acid Sequence ; Apicoplasts/metabolism ; Calcium/metabolism ; Calcium Channels/chemistry ; Calcium Channels/genetics ; Calcium Signaling ; DNA/metabolism ; Endoplasmic Reticulum/metabolism ; Humans ; Mutation ; Organelle Biogenesis ; Phylogeny ; Protozoan Proteins/chemistry ; Protozoan Proteins/genetics
Czasopismo naukowe
Tytuł :
Increasing cytosolic Ca levels restore cell proliferation and stem cell potency in aged MSCs.
Autorzy :
Ahamad N; Department of Periodontics, School of Dentistry, University of Texas Health San Antonio, San Antonio, TX 78229, United States.
Sun Y; Department of Periodontics, School of Dentistry, University of Texas Health San Antonio, San Antonio, TX 78229, United States.
Singh BB; Department of Periodontics, School of Dentistry, University of Texas Health San Antonio, San Antonio, TX 78229, United States.
Pokaż więcej
Źródło :
Stem cell research [Stem Cell Res] 2021 Oct; Vol. 56, pp. 102560. Date of Electronic Publication: 2021 Oct 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Calcium Channels*
Mesenchymal Stem Cells*/metabolism
Animals ; Calcium/metabolism ; Cell Proliferation ; Cells, Cultured ; Mice ; ORAI1 Protein ; Stem Cells/metabolism ; Stromal Interaction Molecule 1 ; TRPC Cation Channels
Czasopismo naukowe
Tytuł :
Targeting late ICaL to close the window to ventricular arrhythmias.
Autorzy :
Gonano LA; Centro de Investigaciones Cardiovasculares Horacio Cingolani, CONICET La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina.
Mattiazzi A; Centro de Investigaciones Cardiovasculares Horacio Cingolani, CONICET La Plata, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, Argentina.
Pokaż więcej
Źródło :
The Journal of general physiology [J Gen Physiol] 2021 Dec 06; Vol. 153 (12). Date of Electronic Publication: 2021 Oct 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Arrhythmias, Cardiac*
Calcium Channels, L-Type*
Humans
Czasopismo naukowe
Tytuł :
Pannexin-1 and CaV1.1 show reciprocal interaction during excitation-contraction and excitation-transcription coupling in skeletal muscle.
Autorzy :
Jaque-Fernández F; Programa de Fisiología y Biofísica, Facultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.
Jorquera G; Programa de Fisiología y Biofísica, Facultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.; Centro de Neurobiología y Fisiopatología Integrativa, Instituto de Fisiología, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.
Troc-Gajardo J; Programa de Fisiología y Biofísica, Facultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.
Pietri-Rouxel F; Université Pierre et Marie Curie, Université Paris 06, Institut National de la Santé et de la Recherche Médicale/Centre National de la Recherche Scientifique/Institut de Myologie/Centre de Recherche en Myologie, Groupement hospitalier universitaire Pitié Salpêtrière, Paris, France.
Gentil C; Université Pierre et Marie Curie, Université Paris 06, Institut National de la Santé et de la Recherche Médicale/Centre National de la Recherche Scientifique/Institut de Myologie/Centre de Recherche en Myologie, Groupement hospitalier universitaire Pitié Salpêtrière, Paris, France.
Buvinic S; Institute for Research in Dental Sciences, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.
Allard B; Université Lyon, Université Claude Bernard Lyon 1, Centre National de la Recherche Scientifique UMR-5310, Institut National de la Santé et de la Recherche Médicale U-1217, Institut NeuroMyoGène, Lyon, France.
Jaimovich E; Programa de Fisiología y Biofísica, Facultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.; Center for Exercise, Metabolism and Cancer, Facultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.
Jacquemond V; Université Lyon, Université Claude Bernard Lyon 1, Centre National de la Recherche Scientifique UMR-5310, Institut National de la Santé et de la Recherche Médicale U-1217, Institut NeuroMyoGène, Lyon, France.
Casas M; Programa de Fisiología y Biofísica, Facultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.; Center for Exercise, Metabolism and Cancer, Facultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.
Pokaż więcej
Źródło :
The Journal of general physiology [J Gen Physiol] 2021 Dec 06; Vol. 153 (12). Date of Electronic Publication: 2021 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels, L-Type*/metabolism
Excitation Contraction Coupling*
Muscle Contraction ; Muscle Fibers, Skeletal/metabolism ; Muscle, Skeletal/metabolism
Czasopismo naukowe
Tytuł :
Differential Immunoexpression of BRAF/V600E, Senescence Markers, PTEN, and T-type Calcium Channels in Acquired Naevi According to their Histopathological and Dermoscopic Classification.
Autorzy :
Moreno S; Department of Dermatology, Hospital Universitari Arnau de Vilanova, University of Lleida, IRBLleida, Avda Alcalde Rovira Roure 80, ES-25198 Lleida, Spain. .
Maiques O
Barcelo C
Romero M
Santacana M
Gómez I
Cuevas D
Velasco A
Vea A
Macia A
Boix R
Valls J
Gatius S
Canti C
Matias-Guiu X
Soria X
Marti RM
Pokaż więcej
Źródło :
Acta dermato-venereologica [Acta Derm Venereol] 2021 Nov 24; Vol. 101 (11), pp. adv00597. Date of Electronic Publication: 2021 Nov 24.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Channels, T-Type*
Nevus, Pigmented*
Skin Neoplasms*
Biomarkers ; Dermoscopy ; Humans ; PTEN Phosphohydrolase ; Proto-Oncogene Proteins B-raf/genetics
Czasopismo naukowe
Tytuł :
Emergence of repurposed drugs as modulators of MCU channel for clinical therapeutics.
Autorzy :
Vishnu N; Department of Medicine, Center for Precision Medicine, University of Texas Health San Antonio, San Antonio, TX, 78229, USA.
Wilson J; College of Arts and Sciences, Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York, 14853, USA. Electronic address: .
Madesh M; Department of Medicine, Center for Precision Medicine, University of Texas Health San Antonio, San Antonio, TX, 78229, USA. Electronic address: .
Pokaż więcej
Źródło :
Cell calcium [Cell Calcium] 2021 Nov; Vol. 99, pp. 102456. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Comment
MeSH Terms :
Calcium Channels*/metabolism
Pharmaceutical Preparations*
Calcium Signaling
Czasopismo naukowe
Tytuł :
The distinct role of the four voltage sensors of the skeletal CaV1.1 channel in voltage-dependent activation.
Autorzy :
Savalli N; Department of Anesthesiology and Perioperative Medicine, Division of Molecular Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Angelini M; Department of Anesthesiology and Perioperative Medicine, Division of Molecular Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Steccanella F; Department of Anesthesiology and Perioperative Medicine, Division of Molecular Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Wier J; Department of Anesthesiology and Perioperative Medicine, Division of Molecular Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Wu F; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Quinonez M; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
DiFranco M; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Neely A; Department of Anesthesiology and Perioperative Medicine, Division of Molecular Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.; Centro Interdisciplinario de Neurociencias de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.
Cannon SC; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Olcese R; Department of Anesthesiology and Perioperative Medicine, Division of Molecular Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Pokaż więcej
Źródło :
The Journal of general physiology [J Gen Physiol] 2021 Nov 01; Vol. 153 (11). Date of Electronic Publication: 2021 Sep 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium Channels, L-Type*/metabolism
Muscle Contraction*
Electrophysiological Phenomena ; Humans ; Kinetics ; Membrane Potentials
Czasopismo naukowe
Tytuł :
Comments on the evolution of TRPV6.
Autorzy :
Wolske K; Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, 66421 Homburg, Saar, Germany. Electronic address: .
Wyatt A; Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, 66421 Homburg, Saar, Germany. Electronic address: .
Wissenbach U; Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, 66421 Homburg, Saar, Germany. Electronic address: .
Pokaż więcej
Źródło :
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft [Ann Anat] 2021 Nov; Vol. 238, pp. 151753. Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Calcium Channels*
TRPV Cation Channels*/genetics
Animals ; Calcium/metabolism ; Female ; Mice ; Placenta ; Pregnancy
Czasopismo naukowe
Tytuł :
The Mitochondrial Ca transfer and NFAT activation.
Autorzy :
Yoast RE; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Emrich SM; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Zhang X; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Xin P; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Arige V; Department of Pharmacology and Physiology, University of Rochester, Rochester, New York, USA.
Pathak T; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Benson JC; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Johnson MT; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Abdelnaby AE; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Lakomski N; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Hempel N; Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Han JM; Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Dupont G; Unité de Chronobiologie Théorique, Université Libre de Bruxelles, Brussels, Belgium.
Yule DI; Department of Pharmacology and Physiology, University of Rochester, Rochester, New York, USA.
Sneyd J; Department of Mathematics, The University of Auckland, Auckland, New Zealand.
Trebak M; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: .
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Oct; Vol. 297 (4), pp. 101174. Date of Electronic Publication: 2021 Sep 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms :
Calcium Signaling*
Calcium/*metabolism
Calcium Channels/*metabolism
Cytosol/*metabolism
Mitochondria/*metabolism
NFATC Transcription Factors/*metabolism
CRISPR-Cas Systems ; Calcium Channels/genetics ; Endoplasmic Reticulum ; Gene Knockout Techniques ; HCT116 Cells ; HEK293 Cells ; Humans ; Jurkat Cells ; Lymphocyte Activation ; NFATC Transcription Factors/genetics ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
The prognosis of epilepsy patients with CACNA1H missense variants: A longitudinal cohort study.
Autorzy :
Wei Z; Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Liu C; Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Wu Z; Department of Anatomy, Histology and Embryology and K.K. Leung Brain Research Centre, School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China.
Cao M; Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Qiao X; Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Han T; Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Zhang Y; Department of Neurology, Xian International Medical Center, People's Republic of China.
Liu Y; Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China.
Deng Y; Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, People's Republic of China. Electronic address: .
Pokaż więcej
Źródło :
Seizure [Seizure] 2021 Oct; Vol. 91, pp. 52-59. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Channels, T-Type*
Epilepsy*/diagnostic imaging
Epilepsy*/drug therapy
Epilepsy*/genetics
Cohort Studies ; Humans ; Longitudinal Studies ; Prognosis ; Prospective Studies
Czasopismo naukowe
Tytuł :
Phenotypic expansion of CACNA1C-associated disorders to include isolated neurological manifestations.
Autorzy :
Rodan LH; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Department of Neurology, Boston Children's Hospital, Boston, MA, USA.
Spillmann RC; Division of Medical Genetics, Department of Pediatrics, Duke Health, Durham, NC, USA.
Kurata HT; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Lamothe SM; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Maghera J; Department of Pharmacology, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Jamra RA; Institute of Human Genetics, University of Leipzig Medical Center, Leipzig, Germany.
Alkelai A; Institute for Genomic Medicine, Columbia University Medical Center, New York, NY, USA.
Antonarakis SE; Medigenome, Swiss Institute of Genomic Medicine, Geneva, Switzerland.
Atallah I; Division of Genetic Medicine, Lausanne University Hospital, Lausanne, Switzerland.
Bar-Yosef O; Pediatric Neurology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hahsomer, Israel.; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Bilan F; CHU de Poitiers, Service de Génétique, EA3808 NEUVACOD, Poitiers, France.
Bjorgo K; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.
Blanc X; Medigenome, Swiss Institute of Genomic Medicine, Geneva, Switzerland.
Van Bogaert P; CHU d'Angers, Service de Pédiatrie, EA3808 NEUVACOD, Angers, France.
Bolkier Y; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.; Pediatric Cardiology Unit, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hahsomer, Israel.
Burrage LC; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Christ BU; Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, SA, South Africa.
Granadillo JL; Division of Genetics and Genomic Medicine, Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Dickson P; Division of Genetics and Genomic Medicine, Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Donald KA; Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, SA, South Africa.
Dubourg C; Service de Génétique Moléculaire et Génomique, CHU, Rennes, France.; University of Rennes, CNRS, IGDR, UMR 6290, Rennes, France.
Eliyahu A; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.; The Danek Gertner Insitute of Human Genetics, Sheba Medical Center, Tel-Hahsomer, Israel.; Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hahsomer, Israel.
Emrick L; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Engleman K; Center for Pediatric Genomic Medicine, Children's Mercy Hospital, Kansas City, MO, USA.
Gonfiantini MV; Rare Diseases and Medical Genetic Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Good JM; Pediatric Neurology, Lausanne University Hospital, Lausanne, Switzerland.
Kalser J; Pediatric Neurology, Lausanne University Hospital, Lausanne, Switzerland.
Kloeckner C; Institute of Human Genetics, University of Leipzig Medical Center, Leipzig, Germany.
Lachmeijer G; Department of Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.
Macchiaiolo M; Rare Diseases and Medical Genetic Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Nicita F; Unit of Neuromuscular and Neurodegenerative Diseases, Department of Neurosciences and Neurorehabilitation, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Odent S; Service de Génétique Clinique, Centre de référence 'Maladies Rares' Anomalies du développement CLAD-Ouest, Hôpital SUD, Échirolles, France.
O'Heir E; Division of Genetics and Genomics, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Center for Mendelian Genomics and Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Ortiz-Gonzalez X; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Pacio-Miguez M; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz, IdiPAZ, CIBERER, ISCIII, Madrid, Spain.
Palomares-Bralo M; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz, IdiPAZ, CIBERER, ISCIII, Madrid, Spain.
Pena L; Cincinnati Children's Hospital and Medical Center Cincinnati, Cincinnati, OH, USA.; University of Cincinnati College of Medicine Cincinnati, Cincinnati, OH, USA.
Platzer K; Institute of Human Genetics, University of Leipzig Medical Center, Leipzig, Germany.
Quinodoz M; Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel, Switzerland.; Department of Ophthalmology, University of Basel, Basel, Switzerland.
Ranza E; Medigenome, Swiss Institute of Genomic Medicine, Geneva, Switzerland.
Rosenfeld JA; Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Roulet-Perez E; Pediatric Neurology, Lausanne University Hospital, Lausanne, Switzerland.
Santani A; Division of Genomic Diagnostics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Santos-Simarro F; Instituto de Genética Médica y Molecular (INGEMM), Hospital Universitario La Paz, IdiPAZ, CIBERER, ISCIII, Madrid, Spain.
Pode-Shakked B; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.; Institute of Rare Diseases, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hahsomer, Israel.
Skraban C; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.; Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Slaugh R; Division of Genetics and Genomic Medicine, Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Superti-Furga A; Pediatric Neurology, Lausanne University Hospital, Lausanne, Switzerland.
Thiffault I; Center for Pediatric Genomic Medicine, Children's Mercy Hospital, Kansas City, MO, USA.
van Jaabrsveld RH; Department of Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.
Vincent M; Service de Génétique Médicale, CHU Nantes, France; Inserm, CNRS, Univ Nantes, l'institut du thorax, Nantes, France.
Wang HG; Cardiovascular Research Institute, Weill Cornell Medicine, New York, NY, USA.
Zacher P; The Saxon Epilepsy Center Kleinwachau, Radeberg, Germany.
Rush E; The Children's Mercy Hospital, Kansas City, MO, USA.; Department of Pediatrics University of Missouri-Kansas City, Kansas City, MO, USA.; Department of Internal Medicine, University of Kansas Medical Center, Kansas City, MO, USA.
Pitt GS; Cardiovascular Research Institute, Weill Cornell Medicine, New York, NY, USA.
Au PYB; Alberta Children's Hospital Research Institute, Department of Genetics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Shashi V; Division of Medical Genetics, Department of Pediatrics, Duke Health, Durham, NC, USA. .
Pokaż więcej
Corporate Authors :
Undiagnosed Diseases Network
Źródło :
Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2021 Oct; Vol. 23 (10), pp. 1922-1932. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Autistic Disorder*/genetics
Calcium Channels, L-Type*/genetics
Long QT Syndrome*
Syndactyly*
Humans ; Phenotype
Czasopismo naukowe
Tytuł :
Primary and secondary motoneurons use different calcium channel types to control escape and swimming behaviors in zebrafish.
Autorzy :
Wen H; Vollum Institute, Oregon Health and Science University, Portland, OR 97239.
Eckenstein K; Vollum Institute, Oregon Health and Science University, Portland, OR 97239.
Weihrauch V; Imaging Core Facility, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Stigloher C; Imaging Core Facility, Biocenter, University of Würzburg, 97074 Würzburg, Germany.
Brehm P; Vollum Institute, Oregon Health and Science University, Portland, OR 97239; .
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 20; Vol. 117 (42), pp. 26429-26437. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Calcium Channels/*metabolism
Calcium Channels/*physiology
Motor Neurons/*metabolism
Animals ; Calcium/metabolism ; Calcium Channels, N-Type/metabolism ; Calcium Channels, P-Type/metabolism ; Calcium Channels, Q-Type/metabolism ; Escape Reaction/physiology ; Motor Neurons/physiology ; Neuromuscular Junction/metabolism ; Presynaptic Terminals/physiology ; Swimming/physiology ; Synapses/metabolism ; Zebrafish/metabolism
Czasopismo naukowe
Tytuł :
Migraine: Calcium Channels and Glia.
Autorzy :
Kowalska M; Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznan, Poland.
Prendecki M; Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznan, Poland.
Piekut T; Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznan, Poland.
Kozubski W; Chair and Department of Neurology, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznan, Poland.
Dorszewska J; Laboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, 49 Przybyszewskiego St., 60-355 Poznan, Poland.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 07; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Calcium Channels/*metabolism
Migraine Disorders/*etiology
Neuroglia/*pathology
Calcitonin Gene-Related Peptide/metabolism ; Calcium/metabolism ; Calcium Channels/genetics ; Calcium Channels, N-Type/chemistry ; Calcium Channels, N-Type/genetics ; Calcium Channels, N-Type/metabolism ; Humans ; Migraine Disorders/drug therapy ; Migraine Disorders/physiopathology ; Mutation ; Neuroglia/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies