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Tytuł :
Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia.
Autorzy :
Bhatt S; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA; Harvard Medical School, Boston, MA, USA; Department of Pharmacy, National University of Singapore, Singapore.
Pioso MS; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA; Harvard Medical School, Boston, MA, USA.
Olesinski EA; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA; Harvard Medical School, Boston, MA, USA.
Yilma B; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA; Harvard Medical School, Boston, MA, USA.
Ryan JA; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA; Harvard Medical School, Boston, MA, USA.
Mashaka T; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA; Harvard Medical School, Boston, MA, USA.
Leutz B; Department of Bioinformatics and Data Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Adamia S; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA.
Zhu H; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA.
Kuang Y; Department of Bioinformatics and Data Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Mogili A; Department of Bioinformatics and Data Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
Louissaint AJ; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA.
Bohl SR; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA; Harvard Medical School, Boston, MA, USA.
Kim AS; Harvard Medical School, Boston, MA, USA; Brigham and Women's Hospital, Boston, MA, USA.
Mehta AK; Breast Tumor Immunology Laboratory, Dana-Farber Cancer Institute, Boston, MA, USA.
Sanghavi S; Novartis Institutes for BioMedical Research, Inc., Cambridge, MA, USA.
Wang Y; Novartis Institutes for BioMedical Research, Inc., Cambridge, MA, USA.
Morris E; Novartis Institutes for BioMedical Research, Inc., Cambridge, MA, USA.
Halilovic E; Novartis Institutes for BioMedical Research, Inc., Cambridge, MA, USA.
Paweletz CP; Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, MA, USA.
Weinstock DM; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA; Harvard Medical School, Boston, MA, USA.
Garcia JS; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA.
Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, 440 Brookline Avenue, M430, Boston, MA 02215, USA; Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 18. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Normal Somatic Mutations in Cancer Transformation.
Autorzy :
Wijewardhane N; Cancer Systems Biology Laboratory, The Francis Crick Institute, London NW1 1AT, UK; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1UL, UK.
Dressler L; Cancer Systems Biology Laboratory, The Francis Crick Institute, London NW1 1AT, UK; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1UL, UK; Department of Medical and Molecular Genetics, King's College London, London WC2R 2LS, UK.
Ciccarelli FD; Cancer Systems Biology Laboratory, The Francis Crick Institute, London NW1 1AT, UK; School of Cancer and Pharmaceutical Sciences, King's College London, London SE1 1UL, UK. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 17. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment.
Autorzy :
Wheeler DA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
Takebe N; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Hinoue T; Van Andel Institute, Grand Rapids, MI 49503, USA.
Hoadley KA; Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Cardenas MF; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
Hamilton AM; Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Laird PW; Van Andel Institute, Grand Rapids, MI 49503, USA.
Wang L; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Johnson A; Foundation Medicine Inc, Cambridge, MA 02141, USA.
Dewal N; Foundation Medicine Inc, Cambridge, MA 02141, USA.
Miller V; Foundation Medicine Inc, Cambridge, MA 02141, USA.
Piñeyro D; Josep Carreras Leukaemia Research Institute, Badalona, 08916 Barcelona, Catalonia, Spain; Institucio Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Catalonia, Spain.
Castro de Moura M; Josep Carreras Leukaemia Research Institute, Badalona, 08916 Barcelona, Catalonia, Spain.
Esteller M; Josep Carreras Leukaemia Research Institute, Badalona, 08916 Barcelona, Catalonia, Spain; Centro de Investigacion Biomedica en Red Cancer (CIBERONC), 28029 Madrid, Spain; Institucio Catalana de Recerca i Estudis Avançats (ICREA), 08010 Barcelona, Catalonia, Spain; Physiological Sciences Department, School of Medicine and Health Sciences, University of Barcelona (UB), 08007 Barcelona, Catalonia, Spain.
Shen H; Van Andel Institute, Grand Rapids, MI 49503, USA.
Zenklusen JC; Center for Cancer Genomics, National Cancer Institute, Bethesda, MD 20892, USA.
Tarnuzzer R; Center for Cancer Genomics, National Cancer Institute, Bethesda, MD 20892, USA.
McShane LM; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Tricoli JV; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Williams PM; Frederick National Laboratory for Cancer Research, Frederick, MD 21701, USA.
Lubensky I; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
O'Sullivan-Coyne G; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Kohn EC; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Little RF; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
White J; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Malik S; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Harris L; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Weil C; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Chen AP; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Karlovich C; Frederick National Laboratory for Cancer Research, Frederick, MD 21701, USA.
Rodgers B; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Shankar L; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Jacobs P; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Nolan T; Department of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Hu J; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
Muzny DM; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
Doddapaneni H; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
Korchina V; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA.
Gastier-Foster J; Nationwide Children's Hospital, Columbus, OH 43205, USA.
Bowen J; Nationwide Children's Hospital, Columbus, OH 43205, USA.
Leraas K; Nationwide Children's Hospital, Columbus, OH 43205, USA.
Edmondson EF; Pathology and Histology Laboratory, Frederick National Laboratory for Cancer Research, National Cancer Institute, NIH, Frederick, MD 21701, USA.
Doroshow JH; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Conley BA; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Ivy SP; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA.
Staudt LM; Center for Cancer Genomics, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 16. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Tumor Mutational Burden as a Pan-cancer Biomarker for Immunotherapy: The Limits and Potential for Convergence.
Autorzy :
Passaro A; Division of Thoracic Oncology, European Institute of Oncology, IRCCS, Milan, Italy.
Stenzinger A; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Peters S; Department of Oncology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 624-625.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Can Genomic Sequencing Identify High-Risk Barrett's Esophagus Earlier Than Pathologists?
Autorzy :
Stachler MD; Department of Pathology, University of California, San Francisco, San Francisco, CA, USA.
Bass AJ; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA; Eli and Edythe L. Broad Institute, Cambridge, MA, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 626-628.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Unraveling the Enigmatic Origin of Neuroblastoma.
Autorzy :
Liu Z; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: .
Thiele CJ; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 618-620.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
PD-L1 Blockade Therapy: Location, Location, Location.
Autorzy :
Brown CC; Immunology Program, Ludwig Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: .
Wolchok JD; Immunology Program, Ludwig Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA; Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 615-617.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The HOLA COVID-19 Study: An International Effort to Determine How COVID-19 Has Impacted Oncology Practices in Latin America.
Autorzy :
Bernabe-Ramirez C; Medical Oncology, Essen Medical, Bronx, NY, USA.
Velazquez AI; Department of Medicine, Division of Hematology/Oncology, University of California, San Francisco, San Francisco, CA, USA; National Clinician Scholars Program, Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, San Francisco, CA, USA.
Olazagasti C; Division of Hematology-Oncology Department of Medicine, Zucker School of Medicine at Hofstra/Northwell Health, New Hyde Park, NY, USA.
Bergerot CD; Centro de Câncer de Brasília (CETTRO), Brasília, DF, Brazil.
Bergerot PG; Centro de Câncer de Brasília (CETTRO), Brasília, DF, Brazil.
Soto-Perez-de-Celis E; Department of Geriatrics, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico.
Duma N; Department of Medicine, Division of Hematology, Medical Oncology and Palliative Care, University of Wisconsin, Madison, WI, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 605-608. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus/*isolation & purification
Coronavirus Infections/*complications
Delivery of Health Care/*statistics & numerical data
Delivery of Health Care/*trends
Neoplasms/*therapy
Pneumonia, Viral/*complications
Practice Guidelines as Topic/*standards
Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Humans ; International Cooperation ; Latin America/epidemiology ; Neoplasms/epidemiology ; Neoplasms/virology ; Pandemics ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Biologically Informed Neural Networks Predict Drug Responses.
Autorzy :
Greene CS; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Childhood Cancer Data Lab, Alex's Lemonade Stand Foundation, Philadelphia, PA 19102, USA. Electronic address: .
Costello JC; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 613-615. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells.
Autorzy :
Kuenzi BM; Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Park J; Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Fong SH; Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA; Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA.
Sanchez KS; Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Lee J; Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Kreisberg JF; Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Ma J; Department of Computer Science, Purdue University, West Lafayette, IN 47907, USA.
Ideker T; Division of Genetics, Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA; Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA; Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 672-684.e6. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Supporting Clinical Decision-Making during the SARS-CoV-2 Pandemic through a Global Research Commitment: The TERAVOLT Experience.
Autorzy :
Trama A; Department of Research, Evaluative Epidemiology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Proto C; Thoracic Oncology Unit, Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Whisenant JG; Department of Medicine, Division of Hematology & Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
Torri V; Laboratory of Clinical Research, Methodology Oncology Department 'Mario Negri' Institute of Pharmacological Researches, IRCCS, Milan, Italy.
Cortellini A; Department of Biotechnology and Applied Clinical Science, University of L'Aquila, L'Aquila, Italy.
Michielin O; Oncology Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Barlesi F; Gustave Roussy Cancer Center, Villejuif, France; Aix Marseille University, CNRS, INSERM, CRCM, Marseille, France.
Dingemans AC; Department of Pulmonology, Erasmus University Medical Center, Rotterdam, and University Maastricht, Maastricht, the Netherlands.
Van Meerbeeck J; Department of Pulmonology and Thoracic Oncology, Antwerp University Hospital, Edegem, Belgium.
Pancaldi V; University Paul Sabatier, Toulouse, Inserm, Centre de Recherche en Cancérologie de Toulouse, Toulouse, France; Barcelona Supercomputing Center, Barcelona.
Mazieres J; Institut Universitaire du Cancer, Centre Hospitalier Universitaire, Toulouse, France.
Soo RA; National University Cancer Institute, Singapore.
Leighl NB; Princess Margaret Cancer Centre, Toronto, Canada.
Peters S; Oncology Department, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Wakelee H; Department of Medicine, Division of Oncology, Stanford University, Stanford, CA, USA.
Horn L; Department of Medicine, Division of Hematology & Oncology, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.
Hellmann M; Medical Oncology, Memorial Sloan Kettering Evelyn H. Lauder Breast Center, New York, NY, USA.
Wong SK; Department of Medicine, Division of Hematology & Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
Garassino MC; Thoracic Oncology Unit, Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: .
Baena J; Medical Oncology Department, Thoracic Cancer and Early Drug Development Unit, Hospital Universitario 12 de Octubre, Madrid, Spain.
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 602-604. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article
MeSH Terms :
Clinical Decision-Making*
Betacoronavirus/*isolation & purification
Coronavirus Infections/*complications
Global Burden of Disease/*standards
Pneumonia, Viral/*complications
Practice Guidelines as Topic/*standards
Thoracic Neoplasms/*therapy
Coronavirus Infections/virology ; Humans ; International Cooperation ; Pandemics ; Pneumonia, Viral/virology ; Registries ; Thoracic Neoplasms/epidemiology ; Thoracic Neoplasms/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Impact of COVID-19 Pandemic on Cancer Research.
Autorzy :
Zon L
Gomes AP
Cance WG
Ribas A
Tuveson D
Postel-Vinay S
Massard C
Barlési F
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 591-593. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus/*isolation & purification
Biomedical Research/*standards
Biomedical Research/*statistics & numerical data
Coronavirus Infections/*epidemiology
Neoplasms/*diagnosis
Neoplasms/*therapy
Pneumonia, Viral/*epidemiology
Coronavirus Infections/virology ; Humans ; Neoplasms/virology ; Pandemics ; Pneumonia, Viral/virology ; United States/epidemiology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
COVID-19: Staging of a New Disease.
Autorzy :
Cordon-Cardo C; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: .
Pujadas E; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Wajnberg A; Department of Medicine, General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sebra R; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Sema4, Mount Sinai Health System, Stamford, CT, USA.
Patel G; Department of Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Firpo-Betancourt A; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Fowkes M; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sordillo E; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Paniz-Mondolfi A; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gregory J; Academic Informatics and Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Krammer F; Tisch Cancer Institute, Division of Hematology/Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Simon V; Academic Informatics and Technology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Tisch Cancer Institute, Division of Hematology/Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Isola L; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Soon-Shiong P; ImmunityBio, LLC, and NantKwest, Inc., Culver City, CA, USA.
Aberg JA; Department of Medicine, Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Fuster V; The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Reich DL; Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 594-597. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Severity of Illness Index*
Virus Internalization*
Virus Replication*
Betacoronavirus/*isolation & purification
Coronavirus Infections/*complications
Inflammation/*etiology
Multiple Organ Failure/*etiology
Pneumonia, Viral/*complications
Coronavirus Infections/epidemiology ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Humans ; Inflammation/pathology ; Multiple Organ Failure/pathology ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Cytokine Storms in Cancer and COVID-19.
Autorzy :
Turnquist C; University of Oxford Medical School, John Radcliffe Hospital, Oxford, UK; Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Ryan BM; Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Horikawa I; Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Harris BT; Departments of Neurology and Pathology, Georgetown University Medical Center, Washington, DC 20007, USA.
Harris CC; Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 598-601. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article
MeSH Terms :
Severity of Illness Index*
Betacoronavirus/*immunology
Coronavirus Infections/*complications
Cytokines/*blood
Inflammation/*etiology
Neoplasms/*immunology
Pneumonia, Viral/*complications
Coronavirus Infections/immunology ; Coronavirus Infections/virology ; Cytokines/immunology ; Humans ; Inflammation/pathology ; Neoplasms/blood ; Neoplasms/virology ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
A High-Resolution Map of Human Enhancer RNA Loci Characterizes Super-enhancer Activities in Cancer.
Autorzy :
Chen H; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Liang H; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 701-715.e5. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Integrated Omics of Metastatic Colorectal Cancer.
Autorzy :
Li C; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China; Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Sun YD; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Yu GY; Colorectal Surgery Department, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Cui JR; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China.
Lou Z; Colorectal Surgery Department, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Zhang H; Colorectal Surgery Department, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Huang Y; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Bai CG; Department of Pathology, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Deng LL; Department of Pathology, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Liu P; Colorectal Surgery Department, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Zheng K; Colorectal Surgery Department, Changhai Hospital, Naval Medical University, Shanghai 200433, China.
Wang YH; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Wang QQ; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Li QR; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China.
Wu QQ; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China.
Liu Q; Department of Biostatistics and Center for Quantitative Sciences, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Shyr Y; Department of Biostatistics and Center for Quantitative Sciences, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Li YX; CAS Key Laboratory of Systems Biology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Hangzhou 310024, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; Bio-Med Big Data Center, Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Chen LN; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China; CAS Key Laboratory of Systems Biology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Hangzhou 310024, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Wu JR; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China; CAS Key Laboratory of Systems Biology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Hangzhou 310024, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China. Electronic address: .
Zhang W; Colorectal Surgery Department, Changhai Hospital, Naval Medical University, Shanghai 200433, China. Electronic address: .
Zeng R; CAS Key Laboratory of Systems Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China; CAS Key Laboratory of Systems Biology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Hangzhou 310024, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 734-747.e9. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
COVID-19 and Cancer: Current Challenges and Perspectives.
Autorzy :
Bakouny Z; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Hawley JE; Division of Hematology and Oncology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA.
Choueiri TK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Peters S; Oncology Department, CHUV, Lausanne, Vaud, Switzerland.
Rini BI; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Warner JL; Division of Hematology and Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.
Painter CA; Cancer Program, Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 629-646. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Betacoronavirus/*isolation & purification
Coronavirus Infections/*complications
Delivery of Health Care/*standards
Neoplasms/*therapy
Pneumonia, Viral/*complications
Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Humans ; Neoplasms/epidemiology ; Neoplasms/virology ; Pandemics ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
A Lung Cancer Patient with Dyspnea: Diagnostic Difficulties during the COVID-19 Pandemic.
Autorzy :
Pruis MA; Department of Pulmonary Diseases, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Hussain B; Department of Radiology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Bakker M; Department of Pulmonary Diseases, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Hoek RAS; Department of Pulmonary Diseases, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Miedema JR; Department of Pulmonary Diseases, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Dingemans AC; Department of Pulmonary Diseases, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
Paats MS; Department of Pulmonary Diseases, Erasmus MC Cancer Institute, Rotterdam, the Netherlands. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 611-612. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Letter
MeSH Terms :
Clinical Laboratory Techniques*
Betacoronavirus/*isolation & purification
Cancer Care Facilities/*statistics & numerical data
Coronavirus Infections/*diagnosis
Dyspnea/*virology
Lung Neoplasms/*virology
Mass Screening/*methods
Pneumonia, Viral/*diagnosis
Coronavirus Infections/complications ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Dyspnea/epidemiology ; Humans ; Lung Neoplasms/epidemiology ; Netherlands/epidemiology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology
SCR Disease Name :
COVID-19
Opinia redakcyjna
Tytuł :
SARS-CoV-2 Viral Load Predicts Mortality in Patients with and without Cancer Who Are Hospitalized with COVID-19.
Autorzy :
Westblade LF; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Brar G; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Pinheiro LC; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.
Paidoussis D; NewYork-Presbyterian Hospital Queens, Queens, NY 11355, USA.
Rajan M; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.
Martin P; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Goyal P; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Sepulveda JL; Department of Pathology, George Washington University, Washington, DC 20037, USA.
Zhang L; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.
George G; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.
Liu D; NewYork-Presbyterian Hospital Queens, Queens, NY 11355, USA.
Whittier S; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA; NewYork-Presbyterian Hospital, Columbia University Medical Center, New York, NY 10032, USA.
Plate M; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Small CB; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Rand JH; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Cushing MM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Walsh TJ; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Cooke J; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; NewYork-Presbyterian Hospital Queens, Queens, NY 11355, USA.
Safford MM; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Loda M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA.
Satlin MJ; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA; NewYork-Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10065, USA. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 661-671.e2. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Viral Load*
Betacoronavirus/*isolation & purification
Coronavirus Infections/*complications
Hospitalization/*statistics & numerical data
Neoplasms/*mortality
Pneumonia, Viral/*complications
Aged ; Aged, 80 and over ; Case-Control Studies ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Neoplasms/epidemiology ; Neoplasms/virology ; New York/epidemiology ; Pandemics ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Prognosis ; Retrospective Studies ; Survival Rate
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes.
Autorzy :
Dammeijer F; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address: .
van Gulijk M; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Mulder EE; Department of Surgical Oncology, Erasmus Medical Center, Rotterdam, the Netherlands.
Lukkes M; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
Klaase L; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
van den Bosch T; Department of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.
van Nimwegen M; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
Lau SP; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Surgical Oncology, Erasmus Medical Center, Rotterdam, the Netherlands.
Latupeirissa K; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
Schetters S; Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
van Kooyk Y; Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Center, Amsterdam, the Netherlands.
Boon L; Polpharma Biologics, Utrecht, the Netherlands.
Moyaart A; Department of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.
Mueller YM; Department of Immunology, Erasmus Medical Center, Rotterdam, the Netherlands.
Katsikis PD; Department of Immunology, Erasmus Medical Center, Rotterdam, the Netherlands.
Eggermont AM; Princess Máxima Center, Utrecht, the Netherlands.
Vroman H; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands.
Stadhouders R; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Cell Biology, Erasmus Medical Center, Rotterdam, the Netherlands.
Hendriks RW; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.
Thüsen JV; Department of Pathology, Erasmus Medical Center, Rotterdam, the Netherlands.
Grünhagen DJ; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Surgical Oncology, Erasmus Medical Center, Rotterdam, the Netherlands.
Verhoef C; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Surgical Oncology, Erasmus Medical Center, Rotterdam, the Netherlands.
van Hall T; Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: .
Aerts JG; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands. Electronic address: .
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Źródło :
Cancer cell [Cancer Cell] 2020 Nov 09; Vol. 38 (5), pp. 685-700.e8. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article
Czasopismo naukowe

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