Autor: "Cao, L." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Cucurbitacin B regulates lung cancer cell proliferation and apoptosis via inhibiting the IL-6/STAT3 pathway through the lncRNA XIST/miR-let-7c axis.
Autorzy:: Liu JH; Department of Respiratory Medicine, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, China.
Li C; Department of Respiratory Medicine, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, China.
Cao L; Department of Respiratory Medicine, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, China.
Zhang CH; Department of Respiratory Medicine, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, China.
Zhang ZH; Department of Respiratory Medicine, The First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei, China.; Pokaż więcej
Źródło:: Pharmaceutical biology [Pharm Biol] 2022 Dec; Vol. 60 (1), pp. 154-162.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents, Phytogenic/*pharmacology
Apoptosis/*drug effects
Lung Neoplasms/*drug therapy
Triterpenes/*pharmacology
A549 Cells ; Antineoplastic Agents, Phytogenic/administration & dosage ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Humans ; Interleukin-6/metabolism ; Lung Neoplasms/genetics ; MicroRNAs/genetics ; RNA, Long Noncoding/genetics ; STAT3 Transcription Factor/metabolism ; Time Factors ; Triterpenes/administration & dosage

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Skocz do pozycji: 2.

Tytuł:: Deoxynivalenol Induces Caspase-8-Mediated Apoptosis through the Mitochondrial Pathway in Hippocampal Nerve Cells of Piglet.
Autorzy:: Cao L; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Jiang Y; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zhu L; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Xu W; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Chu X; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zhang Y; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Rahman SU; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Feng S; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Li Y; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Wu J; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Wang X; College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2021 Jan 20; Vol. 13 (2). Date of Electronic Publication: 2021 Jan 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Caspase 8/*metabolism
Hippocampus/*drug effects
Mitochondria/*drug effects
Trichothecenes/*toxicity
Animals ; Animals, Newborn ; Apoptosis Inducing Factor/genetics ; Apoptosis Inducing Factor/metabolism ; Cell Proliferation/drug effects ; Cells, Cultured ; Hippocampus/enzymology ; Hippocampus/pathology ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/enzymology ; Mitochondria/pathology ; Signal Transduction ; Sus scrofa ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism

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Skocz do pozycji: 3.

Tytuł:: Lead acetate induces apoptosis in Leydig cells by activating PPARγ/caspase-3/PARP pathway.
Autorzy:: Zhou L; Department of Nutrition, School of Public Health, Xuzhou Medical University , Xuzhou, China.
Wang S; Department of Nutrition, School of Public Health, Xuzhou Medical University , Xuzhou, China.
Cao L; Department of Nutrition, School of Public Health, Xuzhou Medical University , Xuzhou, China.
Ren X; Department of Nutrition, School of Public Health, Xuzhou Medical University , Xuzhou, China.
Li Y; Department of Nutrition, School of Public Health, Xuzhou Medical University , Xuzhou, China.
Shao J; Department of Nutrition, School of Public Health, Xuzhou Medical University , Xuzhou, China.
Xu L; Department of Hygiene,School of Public Health, Xuzhou Medical University , China.; Pokaż więcej
Źródło:: International journal of environmental health research [Int J Environ Health Res] 2021 Jan; Vol. 31 (1), pp. 34-44. Date of Electronic Publication: 2019 May 30.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Environmental Pollutants/*toxicity
Lead/*toxicity
Leydig Cells/*drug effects
Animals ; Cell Line ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Male ; Mice

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Skocz do pozycji: 4.

Tytuł:: Role of miR-155-5p expression and its involvement in apoptosis-related factors in thyroid follicular carcinoma.
Autorzy:: Geng X; Department of Thyroid and Breast Surgery, Changzhou No.2 People's Hospital Affiliated to Nanjing Medical University, Changzhou, China.
Sun YY; Department of Pathology, Changzhou No.2 People's Hospital Affiliated to Nanjing Medical University, Changzhou, China.
Fu JJ; Department of Gastroenterology, Changzhou No.2 People's Hospital Affiliated to Nanjing Medical University, Changzhou, China.
Cao L; Department of General Surgery, Changzhou No.2 People's Hospital Affiliated to Nanjing Medical University, Changzhou, China.
Li Y; Department of Thyroid and Breast Surgery, Changzhou No.2 People's Hospital Affiliated to Nanjing Medical University, Changzhou, China.; Pokaż więcej
Źródło:: Journal of clinical pharmacy and therapeutics [J Clin Pharm Ther] 2020 Aug; Vol. 45 (4), pp. 660-665. Date of Electronic Publication: 2020 May 15.
Typ publikacji:: Journal Article
MeSH Terms:: Adenocarcinoma, Follicular/*genetics
Apoptosis/*genetics
MicroRNAs/*genetics
Thyroid Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; Caspase 3/genetics ; Cell Proliferation/genetics ; Female ; Humans ; Lymphatic Metastasis/genetics ; Male ; Middle Aged ; Thyroid Gland/pathology

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Skocz do pozycji: 5.

Tytuł:: Acupuncture Reduces Apoptosis of Granulosa Cells in Rats with Premature Ovarian Failure Via Restoring the PI3K/Akt Signaling Pathway.
Autorzy:: Wang S; Department of Acupuncture, School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Lin S; Department of Acupuncture, School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Zhu M; Department of Acupuncture, School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Li C; Department of Acupuncture, School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Chen S; Department of Acupuncture, School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Pu L; Department of Acupuncture, School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Lin J; Department of Acupuncture, School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Cao L; Formula-pattern Research Center, School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.
Zhang Y; Department of Acupuncture, School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Dec 13; Vol. 20 (24). Date of Electronic Publication: 2019 Dec 13.
Typ publikacji:: Journal Article
MeSH Terms:: Acupuncture Therapy*
Apoptosis*
Primary Ovarian Insufficiency*/metabolism
Primary Ovarian Insufficiency*/pathology
Primary Ovarian Insufficiency*/therapy
Signal Transduction*
Granulosa Cells/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Animals ; Female ; Granulosa Cells/pathology ; Rats ; Rats, Sprague-Dawley

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Skocz do pozycji: 6.

Tytuł:: OsGPAT3 Plays a Critical Role in Anther Wall Programmed Cell Death and Pollen Development in Rice.
Autorzy:: Sun L; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Xiang X; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Yang Z; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Yu P; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Wen X; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Wang H; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Abbas A; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Muhammad Khan R; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Zhang Y; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Cheng S; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .
Cao L; Key Laboratory for Zhejiang Super Rice Research and State Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou 310006, China. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2018 Dec 12; Vol. 19 (12). Date of Electronic Publication: 2018 Dec 12.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*
Oryza/*cytology
Oryza/*metabolism
Plant Proteins/*metabolism
Pollen/*cytology
Pollen/*growth & development
Base Sequence ; Chromosome Mapping ; DNA Fragmentation ; Gene Expression Regulation, Plant ; Genes, Plant ; Genetic Association Studies ; Genetic Complementation Test ; Mutation/genetics ; Oryza/genetics ; Phenotype ; Plant Infertility/genetics ; Plant Proteins/genetics ; Pollen/metabolism ; Pollen/ultrastructure ; Reproducibility of Results

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Skocz do pozycji: 7.

Tytuł:: Zeylenone Induces Mitochondrial Apoptosis and Inhibits Migration and Invasion in Gastric Cancer.
Autorzy:: Yang S; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. .
Liao Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. .
Li L; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. .
Xu X; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. .
Cao L; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 Aug 27; Vol. 23 (9). Date of Electronic Publication: 2018 Aug 27.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Cell Movement/*drug effects
Cyclohexanes/*pharmacology
Dioxanes/*pharmacology
Mitochondria/*drug effects
Proto-Oncogene Proteins c-akt/*metabolism
Animals ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Disease Models, Animal ; Humans ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/metabolism ; Mice ; Signal Transduction/drug effects ; Stomach Neoplasms ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 8.

Tytuł:: Dexmedetomidine attenuates H2O2-induced neonatal rat cardiomyocytes apoptosis through mitochondria- and ER-medicated oxidative stress pathways.
Autorzy:: Liu XR; Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Li T; Key Laboratory of Medical Electrophysiology, Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease/Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Cao L; Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Yu YY; Key Laboratory of Medical Electrophysiology, Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease/Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Chen LL; Key Laboratory of Medical Electrophysiology, Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease/Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Fan XH; Key Laboratory of Medical Electrophysiology, Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease/Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Yang BB; Key Laboratory of Medical Electrophysiology, Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease/Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Tan XQ; Key Laboratory of Medical Electrophysiology, Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease/Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 May; Vol. 17 (5), pp. 7258-7264. Date of Electronic Publication: 2018 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Adrenergic alpha-2 Receptor Agonists/*pharmacology
Apoptosis/*drug effects
Cardiotonic Agents/*pharmacology
Dexmedetomidine/*pharmacology
Myocytes, Cardiac/*drug effects
Oxidative Stress/*drug effects
Animals ; Cells, Cultured ; Endoplasmic Reticulum Stress/drug effects ; Hydrogen Peroxide/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/metabolism ; Rats

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Skocz do pozycji: 9.

Tytuł:: Toosendanin Exerts an Anti-Cancer Effect in Glioblastoma by Inducing Estrogen Receptor β- and p53-Mediated Apoptosis.
Autorzy:: Cao L; Department of Traditional Chinese Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. .
Qu D; Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an 710032, China. .
Wang H; Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an 710032, China. .
Zhang S; Department of Traditional Chinese Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. .
Jia C; Department of Traditional Chinese Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. .
Shi Z; Department of Acupuncture, Shaanxi Hospital of Traditional Chinese Medicine, Xi'an 710032, China. stone_.
Wang Z; Department of Traditional Chinese Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. .
Zhang J; Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an 710032, China. .
Ma J; Department of Traditional Chinese Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2016 Nov 18; Vol. 17 (11). Date of Electronic Publication: 2016 Nov 18.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Brain Neoplasms/*drug therapy
Drugs, Chinese Herbal/*pharmacology
Estrogen Receptor beta/*metabolism
Glioblastoma/*drug therapy
Tumor Suppressor Protein p53/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/genetics ; Blotting, Western ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Dose-Response Relationship, Drug ; Estrogen Receptor beta/genetics ; Flow Cytometry ; Glioblastoma/genetics ; Glioblastoma/metabolism ; Humans ; Immunohistochemistry ; Mice, Nude ; Phytotherapy/methods ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA Interference ; Tumor Suppressor Protein p53/genetics ; Xenograft Model Antitumor Assays ; bcl-2-Associated X Protein/metabolism

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Skocz do pozycji: 10.

Tytuł:: Amelioration of intracellular stress and reduction of neural tube defects in embryos of diabetic mice by phytochemical quercetin.
Autorzy:: Cao L; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Tan C; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.; College of Marine Technology and Environment, Dalian Ocean University, Dalian, China.
Meng F; College of Marine Technology and Environment, Dalian Ocean University, Dalian, China.
Liu P; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Reece EA; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Zhao Z; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Feb 18; Vol. 6, pp. 21491. Date of Electronic Publication: 2016 Feb 18.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Apoptosis/*drug effects
Diabetes Mellitus, Experimental/*metabolism
Neural Tube Defects/*metabolism
Oxidative Stress/*drug effects
Pregnancy in Diabetics/*metabolism
Quercetin/*pharmacology
Animals ; Diabetes Mellitus, Experimental/pathology ; Female ; Mice ; Neural Tube Defects/pathology ; Nitric Oxide Synthase Type II/metabolism ; Pregnancy ; Pregnancy in Diabetics/pathology ; Superoxide Dismutase/metabolism ; Superoxide Dismutase-1/metabolism

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Skocz do pozycji: 11.

Tytuł:: Molecular targeting of the oncoprotein PLK1 in pediatric acute myeloid leukemia: RO3280, a novel PLK1 inhibitor, induces apoptosis in leukemia cells.
Autorzy:: Wang NN; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Li ZH; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Zhao H; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Tao YF; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Xu LX; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Lu J; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. drlujun_.
Cao L; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Du XJ; Department of Gastroenterology, the 5th Hospital of Chinese People's Liberation Army (PLA), Yinchuan 750000, China. du_.
Sun LC; Department of Cell and Molecular Biology, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China. sunlichao_.
Zhao WL; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Xiao PF; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Fang F; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Su GH; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Li YH; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Li G; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Li YP; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Xu YY; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Zhou HT; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Wu Y; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Jin MF; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Liu L; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Ni J; Translational Research Center, Second Hospital, The Second Clinical School, Nanjing Medical University, Nanjing 210000, China. ni_.
Wang J; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Hu SY; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. .
Zhu XM; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. xueming_.
Feng X; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. xing_.
Pan J; Department of Hematology and Oncology, Children's Hospital of Soochow University, Suzhou 215003, China. pan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2015 Jan 07; Vol. 16 (1), pp. 1266-92. Date of Electronic Publication: 2015 Jan 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis/*drug effects
Azepines/*toxicity
Cell Cycle Proteins/*antagonists & inhibitors
Leukemia, Myeloid, Acute/*pathology
Protein Kinase Inhibitors/*toxicity
Protein Serine-Threonine Kinases/*antagonists & inhibitors
Proto-Oncogene Proteins/*antagonists & inhibitors
Pyrimidines/*toxicity
Azepines/chemistry ; Cell Cycle Checkpoints/drug effects ; Cell Cycle Proteins/metabolism ; Child ; Child, Preschool ; Cluster Analysis ; DNA Fragmentation/drug effects ; Down-Regulation/drug effects ; Female ; HL-60 Cells ; Humans ; K562 Cells ; Kaplan-Meier Estimate ; Leukemia, Myeloid, Acute/metabolism ; Leukemia, Myeloid, Acute/mortality ; Male ; Protein Serine-Threonine Kinases/metabolism ; Proto-Oncogene Proteins/metabolism ; Pyrimidines/chemistry ; Tumor Cells, Cultured ; Up-Regulation/drug effects ; Polo-Like Kinase 1