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Wyszukujesz frazę ""Capillary Permeability"" wg kryterium: Temat


Tytuł :
Enhancement degree of brain metastases: correlation analysis between enhanced T2 FLAIR and vascular permeability parameters of dynamic contrast-enhanced MRI.
Autorzy :
Jin T; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhang H; Department of Radiology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Liu X; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Kong X; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Makamure J; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Chen Z; Department of General Surgery, the Affiliated Ganzhou Hospital of Nanchang University, Ganzhou, Jiangxi, China.
Alwalid O; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Yao Z; Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China. .
Wang J; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. .
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Źródło :
European radiology [Eur Radiol] 2021 Aug; Vol. 31 (8), pp. 5595-5604. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Neoplasms*/diagnostic imaging
Capillary Permeability*
Contrast Media ; Humans ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł :
MiR-18a Aggravates Intracranial Hemorrhage by Regulating RUNX1-Occludin/ZO-1 Axis to Increase BBB Permeability.
Autorzy :
Ren S; Guizhou Medical University, Guiyang 550025, China; Department of Emergency, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China.
Wu G; Guizhou Medical University, Guiyang 550025, China; Department of Emergency, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China. Electronic address: .
Huang Y; Department of Emergency, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China.
Wang L; Department of Emergency, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China.
Li Y; Guizhou Medical University, Guiyang 550025, China.
Zhang Y; Guizhou Medical University, Guiyang 550025, China; Department of Emergency, Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2021 Aug; Vol. 30 (8), pp. 105878. Date of Electronic Publication: 2021 May 30.
Typ publikacji :
Journal Article
MeSH Terms :
Capillary Permeability*
Blood-Brain Barrier/*metabolism
Core Binding Factor Alpha 2 Subunit/*metabolism
Intracranial Hemorrhages/*metabolism
MicroRNAs/*metabolism
Occludin/*metabolism
Zonula Occludens-1 Protein/*metabolism
Animals ; Astrocytes/metabolism ; Astrocytes/pathology ; Blood-Brain Barrier/pathology ; Cells, Cultured ; Coculture Techniques ; Core Binding Factor Alpha 2 Subunit/genetics ; Disease Models, Animal ; Electric Impedance ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Intracranial Hemorrhages/genetics ; Intracranial Hemorrhages/pathology ; Male ; MicroRNAs/genetics ; Occludin/genetics ; Rats, Sprague-Dawley ; Signal Transduction ; Zonula Occludens-1 Protein/genetics
Czasopismo naukowe
Tytuł :
An Experimental Workflow for Studying Barrier Integrity, Permeability, and Tight Junction Composition and Localization in a Single Endothelial Cell Monolayer: Proof of Concept.
Autorzy :
Bartosova M; Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Ridinger D; Kirchhoff Institute for Physics, Heidelberg University, 69120 Heidelberg, Germany.
Marinovic I; Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Heigwer J; Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Zhang C; Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Levai E; Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.; 1st Department of Pediatrics, Semmelweis University, 1083 Budapest, Hungary.; ELKH-SE Pediatrics and Nephrology Research Group, 1083 Budapest, Hungary.
Westhoff JH; Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Schaefer F; Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Terjung S; European Molecular Biology Laboratory, Advanced Light Microscopy Facility, 69117 Heidelberg, Germany.
Hildenbrand G; Kirchhoff Institute for Physics, Heidelberg University, 69120 Heidelberg, Germany.
Krunic D; German Cancer Research Center, 69120 Heidelberg, Germany.
Bestvater F; German Cancer Research Center, 69120 Heidelberg, Germany.
Hausmann M; Kirchhoff Institute for Physics, Heidelberg University, 69120 Heidelberg, Germany.
Schmitt CP; Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Zarogiannis SG; Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.; Department of Physiology, Faculty of Medicine, School of Health Sciences, University of Thessaly, BIOPOLIS, 41500 Larissa, Greece.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 30; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article
MeSH Terms :
Capillary Permeability*
Tight Junctions/*metabolism
Claudin-5/metabolism ; Dextrans/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Zonula Occludens-1 Protein/metabolism
Czasopismo naukowe
Tytuł :
COVID-19 ARDS is characterized by higher extravascular lung water than non-COVID-19 ARDS: the PiCCOVID study.
Autorzy :
Shi R; AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de recherche clinique CARMAS, Université Paris-Saclay, 78 rue du Général Leclerc, 94270, Le Kremlin-Bicêtre, France.
Lai C; AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de recherche clinique CARMAS, Université Paris-Saclay, 78 rue du Général Leclerc, 94270, Le Kremlin-Bicêtre, France.
Teboul JL; AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de recherche clinique CARMAS, Université Paris-Saclay, 78 rue du Général Leclerc, 94270, Le Kremlin-Bicêtre, France.
Dres M; AP-HP, Groupe Hospitalier Universitaire APHP-Sorbonne Université, site Pitié-Salpêtrière, Service de Pneumologie, Médecine intensive Réanimation (Département R3S), Paris, France.; INSERM, UMRS_1158 Neurophysiologie respiratoire expérimentale et clinique, Sorbonne Université, Paris, France.
Moretto F; AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de recherche clinique CARMAS, Université Paris-Saclay, 78 rue du Général Leclerc, 94270, Le Kremlin-Bicêtre, France.
De Vita N; Università del Piemonte Orientale, Anestesia e Terapia Intensiva, Azienda Ospedaliero Universitaria 'Maggiore Della Carità', Novara, Italy.
Pham T; AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de recherche clinique CARMAS, Université Paris-Saclay, 78 rue du Général Leclerc, 94270, Le Kremlin-Bicêtre, France.; UVSQ, Univ. Paris-Sud, Inserm, Equipe d'Epidémiologie respiratoire intégrative, CESP, Université Paris-Saclay, 94807, Villejuif, France.
Bonny V; AP-HP, Groupe Hospitalier Universitaire APHP-Sorbonne Université, site Pitié-Salpêtrière, Service de Pneumologie, Médecine intensive Réanimation (Département R3S), Paris, France.; INSERM, UMRS_1158 Neurophysiologie respiratoire expérimentale et clinique, Sorbonne Université, Paris, France.
Mayaux J; AP-HP, Groupe Hospitalier Universitaire APHP-Sorbonne Université, site Pitié-Salpêtrière, Service de Pneumologie, Médecine intensive Réanimation (Département R3S), Paris, France.; INSERM, UMRS_1158 Neurophysiologie respiratoire expérimentale et clinique, Sorbonne Université, Paris, France.
Vaschetto R; Università del Piemonte Orientale, Anestesia e Terapia Intensiva, Azienda Ospedaliero Universitaria 'Maggiore Della Carità', Novara, Italy.
Beurton A; AP-HP, Groupe Hospitalier Universitaire APHP-Sorbonne Université, site Pitié-Salpêtrière, Service de Pneumologie, Médecine intensive Réanimation (Département R3S), Paris, France.; INSERM, UMRS_1158 Neurophysiologie respiratoire expérimentale et clinique, Sorbonne Université, Paris, France.
Monnet X; AP-HP, Service de médecine intensive-réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de recherche clinique CARMAS, Université Paris-Saclay, 78 rue du Général Leclerc, 94270, Le Kremlin-Bicêtre, France. .
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Źródło :
Critical care (London, England) [Crit Care] 2021 Jun 01; Vol. 25 (1), pp. 186. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Clinical Trial; Journal Article; Observational Study
MeSH Terms :
Capillary Permeability*
Severity of Illness Index*
COVID-19/*metabolism
Extravascular Lung Water/*metabolism
Respiratory Distress Syndrome/*metabolism
COVID-19/complications ; Hemodynamics ; Humans ; Lung/blood supply ; Male ; Middle Aged ; Monitoring, Physiologic/methods ; Prognosis ; Pulmonary Edema/metabolism ; Thermodilution
Czasopismo naukowe
Tytuł :
Characterization of a Novel Caveolin Modulator That Reduces Vascular Permeability and Ocular Inflammation.
Autorzy :
Bernatchez PN; Vascular Biology and Therapeutics Program and Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
Tao B; Vascular Biology and Therapeutics Program and Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
Bradshaw RA; CavtheRx, Hamden, CT, USA.
Eveleth D; Trefoil Therapeutics, San Diego, CA, USA.
Sessa WC; Vascular Biology and Therapeutics Program and Department of Pharmacology, Yale University School of Medicine, New Haven, CT, USA.
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Źródło :
Translational vision science & technology [Transl Vis Sci Technol] 2021 May 03; Vol. 10 (6), pp. 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Capillary Permeability*
Vascular Endothelial Growth Factor A*/metabolism
Caveolin 1/genetics ; Endothelial Cells/metabolism ; Humans ; Inflammation/drug therapy
Czasopismo naukowe
Tytuł :
Effects of Ozone on Injury after Gamma Knife Radiosurgery.
Autorzy :
Emon ST; Department of Neurosurgery, Haydarpasa Numune Research and Training Hospital, Istanbul, Turkey. Electronic address: .
Unal S; Institute of Neurological Sciences, Istanbul, Turkey.
Arslanhan A; Institute of Neurological Sciences, Istanbul, Turkey.
Bozkurt SU; Department of Pathology, Marmara University Faculty of Medicine, Istanbul, Turkey.
Meric ZC; Hayat Ozone Center, Istanbul, Turkey.
Ziyal I; Department of Neurosurgery, Marmara University Faculty of Medicine, Istanbul, Turkey.
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Źródło :
World neurosurgery [World Neurosurg] 2021 May; Vol. 149, pp. e982-e988. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji :
Journal Article
MeSH Terms :
Blood-Brain Barrier/*drug effects
Brain/*drug effects
Capillary Permeability/*drug effects
Endothelial Cells/*drug effects
Ozone/*pharmacology
Radiosurgery/*adverse effects
Vasodilation/*drug effects
Animals ; Basigin/drug effects ; Basigin/metabolism ; Basigin/radiation effects ; Blood-Brain Barrier/radiation effects ; Brain/pathology ; Brain/radiation effects ; Brain Edema ; Capillary Permeability/radiation effects ; Edema ; Endothelial Cells/pathology ; Endothelial Cells/radiation effects ; Rats ; Vascular Endothelial Growth Factor A/drug effects ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor A/radiation effects ; Vasodilation/radiation effects
Czasopismo naukowe
Tytuł :
Blood-brain barrier permeability imaging as a predictor for delayed cerebral ischaemia following subarachnoid haemorrhage. A narrative review.
Autorzy :
Amoo M; National Center for Neurosurgery, Beaumont Hospital, Dublin 9, Ireland. .; Royal College of Surgeons in Ireland, Dublin, Ireland. .
Henry J; School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
Pender N; Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Clinical Neuropsychology, Beaumont Hospital, Dublin 9, Ireland.; Department of Academic Neurology, Trinity College Dublin, Dublin, Ireland.
Brennan P; Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.
Campbell M; Department of Genetics, Trinity College Dublin, Dublin, Ireland.
Javadpour M; National Center for Neurosurgery, Beaumont Hospital, Dublin 9, Ireland.; Royal College of Surgeons in Ireland, Dublin, Ireland.; Department of Academic Neurology, Trinity College Dublin, Dublin, Ireland.
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Źródło :
Acta neurochirurgica [Acta Neurochir (Wien)] 2021 May; Vol. 163 (5), pp. 1457-1467. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Capillary Permeability*
Blood-Brain Barrier/*metabolism
Brain Ischemia/*etiology
Subarachnoid Hemorrhage/*complications
Blood-Brain Barrier/pathology ; Humans
Czasopismo naukowe
Tytuł :
Modulation of vascular integrity and neuroinflammation by peroxiredoxin 4 following cerebral ischemia-reperfusion injury.
Autorzy :
Yang J; Department of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China. Electronic address: .
Wang Z; Department of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
Liu X; Department of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
Lu P; Department of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
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Źródło :
Microvascular research [Microvasc Res] 2021 May; Vol. 135, pp. 104144. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Capillary Permeability*
Neuroimmunomodulation*
Blood-Brain Barrier/*enzymology
Endothelial Cells/*enzymology
Inflammation Mediators/*metabolism
Ischemic Stroke/*enzymology
Peroxiredoxins/*metabolism
Reperfusion Injury/*enzymology
Animals ; Blood-Brain Barrier/immunology ; Blood-Brain Barrier/pathology ; Endothelial Cells/immunology ; Endothelial Cells/pathology ; Humans ; Ischemic Stroke/immunology ; Ischemic Stroke/pathology ; Oxidative Stress ; Reactive Oxygen Species/metabolism ; Reperfusion Injury/immunology ; Reperfusion Injury/pathology ; Signal Transduction ; Tight Junctions/enzymology ; Tight Junctions/immunology ; Tight Junctions/pathology
Czasopismo naukowe
Tytuł :
Gastric cancer-secreted exosomal X26nt increases angiogenesis and vascular permeability by targeting VE-cadherin.
Autorzy :
Chen X; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang S; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Du K; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zheng N; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liu Y; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen H; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xie G; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ma Y; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhou Y; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zheng Y; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zeng L; School of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Yang J; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shen L; Department of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Faculty of Medical Laboratory Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Xin Hua Children's Hospital, Shanghai, China.
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Źródło :
Cancer science [Cancer Sci] 2021 May; Vol. 112 (5), pp. 1839-1852. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Capillary Permeability*
Antigens, CD/*metabolism
Cadherins/*metabolism
Exosomes/*metabolism
Neovascularization, Pathologic/*etiology
RNA, Long Noncoding/*metabolism
Stomach Neoplasms/*blood supply
3' Untranslated Regions ; Animals ; Antigens, CD/genetics ; Cadherins/genetics ; Cell Communication ; Cell Movement ; Cell Proliferation ; Endoribonucleases/metabolism ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Protein Splicing ; Protein-Serine-Threonine Kinases/metabolism ; RNA, Messenger/metabolism ; Stomach Neoplasms/metabolism ; X-Box Binding Protein 1/metabolism
Czasopismo naukowe
Tytuł :
YAP expression in endothelial cells prevents ventilator-induced lung injury.
Autorzy :
Su K; Department of Anesthesiology, University of Illinois College of Medicine, Chicago, Illinois.; Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Wang J; Department of Anesthesiology, University of Illinois College of Medicine, Chicago, Illinois.; Department of Anesthesiology, Affiliated Hospital of Jining Medical University, Shandong, China.
Lv Y; Department of Anesthesiology, University of Illinois College of Medicine, Chicago, Illinois.
Tian M; Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Zhao YY; Program for Lung and Vascular Biology, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.; Division of Critical Care, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Minshall RD; Department of Anesthesiology, University of Illinois College of Medicine, Chicago, Illinois.; Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois.
Hu G; Department of Anesthesiology, University of Illinois College of Medicine, Chicago, Illinois.; Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Apr 01; Vol. 320 (4), pp. L568-L582. Date of Electronic Publication: 2021 Feb 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Capillary Permeability*
Adaptor Proteins, Signal Transducing/*physiology
Endothelium, Vascular/*metabolism
Lung/*metabolism
Neutrophils/*immunology
Ventilator-Induced Lung Injury/*prevention & control
Animals ; Antigens, CD/metabolism ; Cadherins/metabolism ; Endothelium, Vascular/cytology ; Endothelium, Vascular/immunology ; Female ; Lung/cytology ; Lung/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neutrophils/metabolism ; Phosphorylation ; Ventilator-Induced Lung Injury/etiology ; Ventilator-Induced Lung Injury/metabolism ; Ventilator-Induced Lung Injury/pathology
Czasopismo naukowe
Tytuł :
Rho GTPases in Retinal Vascular Diseases.
Autorzy :
Uemura A; Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.; Department of Cell Biology, National Cerebral and Cardiovascular Center Research Institute, Osaka 564-8565, Japan.; Proteo-Science Center, Ehime University, Toon 791-0295, Japan.; Uemura Eye Clinic, Nishinomiya 663-8101, Japan.
Fukushima Y; Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka 563-0871, Japan.; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka 565-0871, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 01; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Capillary Permeability*
Neovascularization, Physiologic*
Retinal Diseases/*enzymology
Vascular Diseases/*enzymology
rho GTP-Binding Proteins/*metabolism
Cell Movement ; Endothelial Cells/physiology ; Humans ; Molecular Targeted Therapy
Czasopismo naukowe
Tytuł :
UCHL1, a deubiquitinating enzyme, regulates lung endothelial cell permeability in vitro and in vivo.
Autorzy :
Mitra S; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana.
Epshtein Y; Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois.
Sammani S; Department of Medicine, Arizona Health Sciences Center, University of Arizona, Tucson, Arizona.
Quijada H; Department of Medicine, Arizona Health Sciences Center, University of Arizona, Tucson, Arizona.
Chen W; Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois.
Bandela M; Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois.
Desai AA; Department of Medicine, Indiana University School of Medicine, Bloomington, Indiana.
Garcia JGN; Department of Medicine, Arizona Health Sciences Center, University of Arizona, Tucson, Arizona.
Jacobson JR; Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Apr 01; Vol. 320 (4), pp. L497-L507. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Capillary Permeability*
Endothelium, Vascular/*pathology
Ubiquitin Thiolesterase/*metabolism
Ventilator-Induced Lung Injury/*pathology
Animals ; Cells, Cultured ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; In Vitro Techniques ; Indoles/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Oximes/pharmacology ; Signal Transduction ; Ubiquitin Thiolesterase/antagonists & inhibitors ; Ubiquitin Thiolesterase/genetics ; Ubiquitination ; Ventilator-Induced Lung Injury/metabolism
Czasopismo naukowe
Tytuł :
Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure.
Autorzy :
Michalick L; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Weidenfeld S; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Grimmer B; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Fatykhova D; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Solymosi PD; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Behrens F; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany.
Dohmen M; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; Max Delbrück Center for Molecular Medicine, Berlin, Germany.
Brack MC; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Schulz S; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Thomasch E; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Simmons S; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Müller-Redetzky H; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Suttorp N; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; German Center for Lung Research (DZL), Germany.
Kurth F; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Neudecker J; Dept of General, Visceral, Vascular and Thoracic Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Toennies M; Lungenklinik Heckeshorn, HELIOS Klinikum Emil von Behring, Berlin, Germany.
Bauer TT; Lungenklinik Heckeshorn, HELIOS Klinikum Emil von Behring, Berlin, Germany.
Eggeling S; Vivantes Netzwerk für Gesundheit, Klinikum Neukölln, Klinik für Thoraxchirurgie, Berlin, Germany.
Corman VM; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; German Centre for Infection Research (DZIF), Germany.
Hocke AC; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; German Center for Lung Research (DZL), Germany.
Witzenrath M; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; German Center for Lung Research (DZL), Germany.; These authors contributed equally to this study.
Hippenstiel S; Dept of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; German Center for Lung Research (DZL), Germany.; These authors contributed equally to this study.
Kuebler WM; Institute of Physiology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany .; German Center for Lung Research (DZL), Germany.; The Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.; Depts. of Surgery and Physiology, University of Toronto, Toronto, ON, Canada.; German Centre for Cardiovascular Research (DZHK), Germany.; These authors contributed equally to this study.
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Źródło :
The European respiratory journal [Eur Respir J] 2021 Mar 11; Vol. 57 (3). Date of Electronic Publication: 2021 Mar 11 (Print Publication: 2021).
Typ publikacji :
Letter
MeSH Terms :
Capillary Permeability*
Electric Impedance*
Plasma*
COVID-19/*metabolism
Endothelial Cells/*metabolism
Endothelium/*metabolism
Actins/metabolism ; Antigens, CD/metabolism ; COVID-19/blood ; Cadherins/metabolism ; Case-Control Studies ; Hospitalization ; Humans ; Lung/metabolism ; Microvessels/cytology ; Occludin/metabolism ; SARS-CoV-2 ; Severity of Illness Index
Opinia redakcyjna
Tytuł :
Glycolysis is integral to histamine-induced endothelial hyperpermeability.
Autorzy :
Ziogas A; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
Sajib MS; Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA.
Lim JH; Department of Basic and Translational Sciences, Laboratory of Innate Immunity and Inflammation, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Alves TC; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
Das A; Department of Physiology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.
Witt A; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
Hagag E; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
Androulaki N; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
Grossklaus S; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
Gerlach M; Core Facility Cellular Imaging (CFCI), Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.
Noll T; Department of Physiology, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.
Grinenko T; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
Mirtschink P; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
Hajishengallis G; Department of Basic and Translational Sciences, Laboratory of Innate Immunity and Inflammation, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Chavakis T; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
Mikelis CM; Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA.
Sprott D; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine and University Clinic Carl Gustav Carus, TU Dresden, Dresden, Germany.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Mar; Vol. 35 (3), pp. e21425.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Capillary Permeability/*physiology
Endothelial Cells/*drug effects
Glycolysis/*physiology
Histamine/*pharmacology
Adherens Junctions/drug effects ; Adherens Junctions/metabolism ; Anaphylaxis/metabolism ; Anaphylaxis/pathology ; Animals ; Capillary Permeability/drug effects ; Endothelial Cells/metabolism ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Mice ; Phospholipase C beta/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Elevated Plasma Concentrations of Syndecan-1 Do Not Correlate With Increased Capillary Leakage of 20% Albumin.
Autorzy :
Hahn RG; From the Research Unit, Södertälje Hospital, Södertälje, Sweden.; Karolinska Institutet at Danderyds Hospital (KIDS).
Zdolsek M; Department Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.
Krizhanovskii C; From the Research Unit, Södertälje Hospital, Södertälje, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet.
Ntika S; From the Research Unit, Södertälje Hospital, Södertälje, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet.
Zdolsek J; Department Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.
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Źródło :
Anesthesia and analgesia [Anesth Analg] 2021 Mar 01; Vol. 132 (3), pp. 856-865.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Capillary Permeability*
Fluid Therapy*/adverse effects
Albumins/*administration & dosage
Burns/*therapy
Endothelial Cells/*metabolism
Glycocalyx/*metabolism
Syndecan-1/*blood
Adult ; Aged ; Albumins/adverse effects ; Biomarkers/blood ; Burns/blood ; Burns/physiopathology ; Female ; Heparitin Sulfate/blood ; Humans ; Infusions, Intravenous ; Male ; Middle Aged ; Prospective Studies ; Sweden ; Time Factors ; Up-Regulation
Czasopismo naukowe
Tytuł :
A Novel Experimental Approach for In Vivo Analyses of the Salivary Gland Microvasculature.
Autorzy :
Uhl B; Department of Otorhinolaryngology-Head and Neck Surgery, Ludwig-Maximilians-Universität München, Munich, Germany.; Walter Brendel Centre for Experimental Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Braun C; Walter Brendel Centre for Experimental Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Dominik J; Walter Brendel Centre for Experimental Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Luft J; Walter Brendel Centre for Experimental Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Canis M; Department of Otorhinolaryngology-Head and Neck Surgery, Ludwig-Maximilians-Universität München, Munich, Germany.
Reichel CA; Department of Otorhinolaryngology-Head and Neck Surgery, Ludwig-Maximilians-Universität München, Munich, Germany.; Walter Brendel Centre for Experimental Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Feb 17; Vol. 11, pp. 604470. Date of Electronic Publication: 2021 Feb 17 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Capillary Permeability*/drug effects
Chemotaxis, Leukocyte*/drug effects
Leukocyte Rolling*/drug effects
Cell Adhesion Molecules/*metabolism
Inflammation/*metabolism
Leukocytes/*metabolism
Microvessels/*metabolism
Submandibular Gland/*blood supply
Animals ; Antibodies/pharmacology ; Flow Cytometry ; Inflammation/immunology ; Inflammation/pathology ; Leukocytes/drug effects ; Leukocytes/immunology ; Male ; Mice, Inbred C57BL ; Microscopy, Confocal ; Microscopy, Fluorescence, Multiphoton ; Microvessels/drug effects ; Microvessels/immunology ; Microvessels/pathology ; Phenotype ; Signal Transduction ; Tumor Necrosis Factor-alpha/pharmacology
Czasopismo naukowe
Tytuł :
Blood-brain barrier permeability towards small and large tracers in a mouse model of osmotic demyelination syndrome.
Autorzy :
Scalisi J; URPhyM - NARILIS, Université de Namur, Namur, Belgium; HEPH-Condorcet, Catégorie Paramédicale Charleroi, Charleroi, Belgium. Electronic address: .
Balau B; URPhyM - NARILIS, Université de Namur, Namur, Belgium. Electronic address: .
Deneyer L; URPhyM - NARILIS, Université de Namur, Namur, Belgium; HEPH-Condorcet, Catégorie Paramédicale Charleroi, Charleroi, Belgium. Electronic address: .
Bouchat J; URPhyM - NARILIS, Université de Namur, Namur, Belgium. Electronic address: .
Gilloteaux J; URPhyM - NARILIS, Université de Namur, Namur, Belgium; Department of Anatomical Sciences, St George's University School of Medicine, Newcastle upon Tyne, United Kingdom. Electronic address: .
Nicaise C; URPhyM - NARILIS, Université de Namur, Namur, Belgium. Electronic address: .
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Źródło :
Neuroscience letters [Neurosci Lett] 2021 Feb 16; Vol. 746, pp. 135665. Date of Electronic Publication: 2021 Jan 23.
Typ publikacji :
Journal Article
MeSH Terms :
Blood-Brain Barrier/*metabolism
Capillary Permeability/*physiology
Demyelinating Diseases/*metabolism
Fluorescent Dyes/*metabolism
Osmosis/*physiology
Animals ; Biological Transport/drug effects ; Biological Transport/physiology ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/pathology ; Capillary Permeability/drug effects ; Demyelinating Diseases/pathology ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Fluorescent Dyes/administration & dosage ; Male ; Mice ; Mice, Inbred C57BL ; Osmosis/drug effects ; Syndrome
Czasopismo naukowe
Tytuł :
β 1- and β 2-integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation.
Autorzy :
Ou Z; Department of Medicine, Division of Cardiology, Emory University, Atlanta, Georgia.
Dolmatova E; Department of Medicine, Division of Cardiology, Emory University, Atlanta, Georgia.
Lassègue B; Department of Medicine, Division of Cardiology, Emory University, Atlanta, Georgia.
Griendling KK; Department of Medicine, Division of Cardiology, Emory University, Atlanta, Georgia.
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Źródło :
American journal of physiology. Heart and circulatory physiology [Am J Physiol Heart Circ Physiol] 2021 Feb 01; Vol. 320 (2), pp. H734-H739. Date of Electronic Publication: 2020 Dec 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Capillary Permeability*
Chemotaxis, Leukocyte*
CD18 Antigens/*metabolism
Endothelium, Vascular/*metabolism
Inflammation/*metabolism
Inflammation Mediators/*metabolism
Integrin beta1/*metabolism
Leukocytes/*metabolism
Animals ; Cell Adhesion ; Cell Communication ; Endothelium, Vascular/immunology ; Endothelium, Vascular/physiopathology ; Humans ; Inflammation/immunology ; Inflammation/physiopathology ; Leukocyte Rolling ; Leukocytes/immunology ; Signal Transduction ; Transendothelial and Transepithelial Migration
Czasopismo naukowe
Tytuł :
Macrophage-mediated vascular permeability via VLA4/VCAM1 pathway dictates ascites development in ovarian cancer.
Autorzy :
Zhang S; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Xie B; Department of Gynaecology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Wang L; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Yang H; Department of Gynaecology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Zhang H; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Chen Y; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Wang F; Department of Gynaecology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Liu C; Department of Gynaecology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
He H; Guangdong Provincial Key Laboratory of Biomedical Imaging and Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2021 Feb 01; Vol. 131 (3).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Capillary Permeability*
Macrophages*/metabolism
Macrophages*/pathology
Ovarian Neoplasms*/blood supply
Ovarian Neoplasms*/metabolism
Ovarian Neoplasms*/pathology
Signal Transduction*
Ascites/*metabolism
Integrin alpha4beta1/*metabolism
Neoplasm Proteins/*metabolism
Vascular Cell Adhesion Molecule-1/*metabolism
Animals ; Ascites/pathology ; Female ; Human Umbilical Vein Endothelial Cells ; Humans ; Mice ; RAW 264.7 Cells ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Oestrogen-mediated upregulation of the Mas receptor contributes to sex differences in acute lung injury and lung vascular barrier regulation.
Autorzy :
Erfinanda L; Institute of Physiology, Charité - Universitätsmedizin, Berlin, Germany.
Ravindran K; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.
Kohse F; Institute of Physiology, Charité - Universitätsmedizin, Berlin, Germany.; Institute of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Greifswald, Germany.
Gallo K; Institute of Physiology, Charité - Universitätsmedizin, Berlin, Germany.
Preissner R; Institute of Physiology, Charité - Universitätsmedizin, Berlin, Germany.
Walther T; Institute of Medical Biochemistry and Molecular Biology, University Medicine Greifswald, Greifswald, Germany .; Dept of Pharmacology and Therapeutics, School of Medicine, University College Cork, Cork, Ireland.; Shared senior authorship.
Kuebler WM; Institute of Physiology, Charité - Universitätsmedizin, Berlin, Germany.; Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.; Dept of Physiology and Dept of Surgery, University of Toronto, Toronto, ON, Canada.; Shared senior authorship.
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Źródło :
The European respiratory journal [Eur Respir J] 2021 Jan 21; Vol. 57 (1). Date of Electronic Publication: 2021 Jan 21 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Acute Lung Injury/*genetics
Angiotensin I/*metabolism
COVID-19/*epidemiology
Capillary Permeability/*genetics
Endothelium, Vascular/*metabolism
Estrogens/*metabolism
Lung/*metabolism
Peptide Fragments/*metabolism
Proto-Oncogene Proteins/*genetics
Receptors, G-Protein-Coupled/*genetics
Respiratory Distress Syndrome/*epidemiology
Acute Lung Injury/metabolism ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Angiotensin I/pharmacology ; Angiotensin-Converting Enzyme 2 ; Animals ; Capillary Permeability/drug effects ; Child ; Electric Impedance ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Estradiol/pharmacology ; Female ; Humans ; In Vitro Techniques ; Lung/drug effects ; Male ; Mice ; Mice, Knockout ; Middle Aged ; Ovariectomy ; Peptide Fragments/pharmacology ; Platelet Activating Factor/pharmacology ; Proto-Oncogene Proteins/metabolism ; Receptors, G-Protein-Coupled/metabolism ; SARS-CoV-2 ; Sex Distribution ; Sex Factors ; Up-Regulation ; Young Adult
Czasopismo naukowe

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