Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Carbazoles"" wg kryterium: Temat


Tytuł :
Identification of an orally active carbazole aminoalcohol derivative with broad-spectrum anti-animal trypanosomiasis activity.
Autorzy :
Cai XL; Center for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, P.R. China.
Wang W; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Tropical Diseases, Key Laboratory of Parasitology and Vector Biology of the Chinese Ministry of Health, Shanghai 200025, P.R. China.
Lai DH; Center for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, P.R. China.
Zhang X; Center for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, P.R. China.
Yao J; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Tropical Diseases, Key Laboratory of Parasitology and Vector Biology of the Chinese Ministry of Health, Shanghai 200025, P.R. China.
Yu Y; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Tropical Diseases, Key Laboratory of Parasitology and Vector Biology of the Chinese Ministry of Health, Shanghai 200025, P.R. China.
Li S; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Tropical Diseases, Key Laboratory of Parasitology and Vector Biology of the Chinese Ministry of Health, Shanghai 200025, P.R. China.
Hide G; Ecosystems and Environment Research Centre and Biomedical Research Centre, School of Science, Engineering and Environment, University of Salford, Salford, UK.
Bai H; School of Life Science, Tarim University, Alaer 843300, P.R. China.
Duan L; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Centre for Tropical Diseases, Key Laboratory of Parasitology and Vector Biology of the Chinese Ministry of Health, Shanghai 200025, P.R. China; School of Life Science, Tarim University, Alaer 843300, P.R. China. Electronic address: .
Lun ZR; Center for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, P.R. China; Ecosystems and Environment Research Centre and Biomedical Research Centre, School of Science, Engineering and Environment, University of Salford, Salford, UK. Electronic address: .
Pokaż więcej
Źródło :
Acta tropica [Acta Trop] 2021 Jul; Vol. 219, pp. 105919. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Alcohols/*chemistry
Carbazoles/*chemistry
Carbazoles/*pharmacology
Trypanocidal Agents/*chemistry
Trypanocidal Agents/*pharmacology
Trypanosomiasis/*drug therapy
Administration, Oral ; Animals ; Carbazoles/administration & dosage ; Carbazoles/therapeutic use ; Mice ; Trypanocidal Agents/administration & dosage ; Trypanocidal Agents/therapeutic use ; Trypanosoma brucei brucei/drug effects ; Trypanosoma brucei brucei/physiology
Czasopismo naukowe
Tytuł :
N,N'-bicarbazole-benzothiadiazole-based conjugated porous organic polymer for reactive oxygen species generation in live cells.
Autorzy :
Kundu S; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhauri, Bhopal 462066, Madhya Pradesh, India. .
Behera B; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhauri, Bhopal 462066, Madhya Pradesh, India. .
Giri A; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhauri, Bhopal 462066, Madhya Pradesh, India. .
Saha N; Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal, Bhauri, Bhopal 462066, Madhya Pradesh, India.
Patra A; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhauri, Bhopal 462066, Madhya Pradesh, India. .
Pokaż więcej
Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Jul 18; Vol. 57 (56), pp. 6875-6878. Date of Electronic Publication: 2021 Jun 21.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Carbazoles/*pharmacology
Photosensitizing Agents/*pharmacology
Polymers/*pharmacology
Reactive Oxygen Species/*metabolism
Thiadiazoles/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/radiation effects ; Carbazoles/chemical synthesis ; Carbazoles/radiation effects ; HeLa Cells ; Humans ; Light ; Photosensitizing Agents/chemical synthesis ; Photosensitizing Agents/radiation effects ; Polymers/chemical synthesis ; Polymers/radiation effects ; Porosity ; Thiadiazoles/chemical synthesis ; Thiadiazoles/radiation effects
Czasopismo naukowe
Tytuł :
Synthesis and Bioinformatic Characterization of New Schiff Bases with Possible Applicability in Brain Disorders.
Autorzy :
Avram S; Department of Anatomy, Animal Physiology, and Biophysics, Faculty of Biology, University of Bucharest, 36-46 M. Kogălniceanu Boulevard, 050107 Bucharest, Romania.
Udrea AM; National Institute of Laser, Plasma and Radiation Physics, 409 Atomistilor Str., 077125 Magurele, Romania.
Nuta DC; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Limban C; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Balea AC; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Caproiu MT; The Organic Chemistry Center of Romanian Academy 'C. D. Neniţescu', Splaiul Independenţei 202B, 060023 Bucharest, Romania.
Dumitrascu F; The Organic Chemistry Center of Romanian Academy 'C. D. Neniţescu', Splaiul Independenţei 202B, 060023 Bucharest, Romania.
Buiu C; Department of Automatic Control and Systems Engineering, Politehnica University of Bucharest, Spl. Independenţei 313, 060042 Bucharest, Romania.
Bordei AT; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 'Carol Davila' University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956 Bucharest, Romania.
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 08; Vol. 26 (14). Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article
MeSH Terms :
Carbazoles/*chemistry
Schiff Bases/*chemical synthesis
Schiff Bases/*chemistry
Aldehydes/chemistry ; Anti-Bacterial Agents/pharmacology ; Carbazoles/chemical synthesis ; Carbazoles/pharmacology ; Cheminformatics/methods ; Computational Biology/methods ; Glucosamine/chemistry ; Molecular Structure ; Neurodegenerative Diseases/drug therapy ; Spectroscopy, Fourier Transform Infrared/methods
Czasopismo naukowe
Tytuł :
Inhibiting SARS-CoV-2 infection in vitro by suppressing its receptor, angiotensin-converting enzyme 2, via aryl-hydrocarbon receptor signal.
Autorzy :
Tanimoto K; Department of Radiation Disaster Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, 734-8553, Japan. .
Hirota K; Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, 573-1010, Japan.
Fukazawa T; Natural Science Center for Basic Research and Development, Hiroshima University, Hiroshima, 734-8553, Japan.
Matsuo Y; Department of Human Stress Response Science, Institute of Biomedical Science, Kansai Medical University, Hirakata, 573-1010, Japan.
Nomura T; Department of Virology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.
Tanuza N; Department of Virology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.
Hirohashi N; Department of Radiation Disaster Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, 734-8553, Japan.
Bono H; Program of Biomedical Science, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, 739-0046, Japan.
Sakaguchi T; Department of Virology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2021 Aug 17; Vol. 11 (1), pp. 16629. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin-Converting Enzyme 2/*antagonists & inhibitors
Basic Helix-Loop-Helix Transcription Factors/*agonists
COVID-19/*drug therapy
Carbazoles/*pharmacology
Omeprazole/*pharmacology
Receptors, Aryl Hydrocarbon/*agonists
Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; COVID-19/virology ; Carbazoles/therapeutic use ; Chlorocebus aethiops ; Cytochrome P-450 CYP1A1/metabolism ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Gene Expression Regulation/drug effects ; Gene Knockdown Techniques ; Hep G2 Cells ; Humans ; Omeprazole/therapeutic use ; RNA-Seq ; Receptors, Aryl Hydrocarbon/metabolism ; SARS-CoV-2/drug effects ; SARS-CoV-2/pathogenicity ; Signal Transduction/drug effects ; Vero Cells ; Virus Internalization/drug effects
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Water Modulated Diastereoselective Synthesis of cis / trans -Spiro[indoline-3,6'-naphtho[2,3- c ]carbazoles].
Autorzy :
Yan C; College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
Sun J; College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
Han Y; College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
Yan CG; College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
Pokaż więcej
Źródło :
The Journal of organic chemistry [J Org Chem] 2021 Jul 16; Vol. 86 (14), pp. 9263-9279. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carbazoles*
Spiro Compounds*
Indoles ; Molecular Structure ; Water
Czasopismo naukowe
Tytuł :
High throughput extraction strategy for simultaneous analysis of 19 tetrabromobisphenol A and halogenated carbazole analogs in seafood.
Autorzy :
Xu H; College of Environmental Science and Engineering, Qingdao University, 266071 Qingdao, China.
Zheng M; Marine Ecology Research Center, First Institute of Oceanography, Ministry of Natural Resources, 266061 Qingdao, China.
Wang L; College of Environmental Science and Engineering, Qingdao University, 266071 Qingdao, China.
Zhao W; College of Environmental Science and Engineering, Qingdao University, 266071 Qingdao, China.
Hua Y; College of Environmental Science and Engineering, Qingdao University, 266071 Qingdao, China.
Fang L; College of Environmental Science and Engineering, Qingdao University, 266071 Qingdao, China.
Liu A; College of Environmental Science and Engineering, Qingdao University, 266071 Qingdao, China. Electronic address: .
Zhao Z; College of Environmental Science and Engineering, Qingdao University, 266071 Qingdao, China.
Pokaż więcej
Źródło :
Food chemistry [Food Chem] 2021 Jul 15; Vol. 350, pp. 129214. Date of Electronic Publication: 2021 Feb 08.
Typ publikacji :
Journal Article
MeSH Terms :
Halogenation*
Carbazoles/*analysis
Chemical Fractionation/*methods
Food Analysis/*methods
Polybrominated Biphenyls/*analysis
Polybrominated Biphenyls/*isolation & purification
Seafood/*analysis
Carbazoles/chemistry ; Environmental Pollutants/analysis ; Environmental Pollutants/chemistry ; Food Contamination ; Time Factors
Czasopismo naukowe
Tytuł :
Development of Alectinib-Based PROTACs as Novel Potent Degraders of Anaplastic Lymphoma Kinase (ALK).
Autorzy :
Xie S; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Sun Y; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Liu Y; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.; Department of Organic Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Li X; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Li X; Key Lab of Drug Metabolism & Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Zhong W; Department of Organic Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Zhan F; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Zhu J; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Yao H; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Yang DH; College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, New York 11439, United States.
Chen ZS; College of Pharmacy and Health Sciences, St. John's University, 8000 Utopia Parkway, Queens, New York 11439, United States.
Xu J; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Xu S; State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, P. R. China.
Pokaż więcej
Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Jul 08; Vol. 64 (13), pp. 9120-9140. Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Development*
Anaplastic Lymphoma Kinase/*antagonists & inhibitors
Antineoplastic Agents/*pharmacology
Carbazoles/*pharmacology
Piperidines/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Anaplastic Lymphoma Kinase/metabolism ; Animals ; Antineoplastic Agents/chemistry ; Carbazoles/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Mice ; Molecular Structure ; Neoplasms, Experimental/drug therapy ; Neoplasms, Experimental/metabolism ; Neoplasms, Experimental/pathology ; Piperidines/chemistry ; Protein Kinase Inhibitors/chemistry ; Proteolysis/drug effects ; Rats ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
In vivo pharmacokinetic evaluation of carprofen delivery from intra-articular nanoparticles in rabbits: A population modelling approach.
Autorzy :
Parra-Coca A; Department of Pharmacy and Pharmaceutical technology and Physical-Chemistry, Faculty of Pharmacy and Food sciences, University of Barcelona, ES, Spain; Department of Veterinary Medicine and Zootechnic, Faculty of Agricultural Sciences, University of Applied and Environmental Sciences (U.D.C.A.), Bogotá, CO, Colombia.
Boix-Montañés A; Department of Pharmacy and Pharmaceutical technology and Physical-Chemistry, Faculty of Pharmacy and Food sciences, University of Barcelona, ES, Spain. Electronic address: .
Calpena-Campmany AC; Department of Pharmacy and Pharmaceutical technology and Physical-Chemistry, Faculty of Pharmacy and Food sciences, University of Barcelona, ES, Spain.
Colom H; Department of Pharmacy and Pharmaceutical technology and Physical-Chemistry, Faculty of Pharmacy and Food sciences, University of Barcelona, ES, Spain.
Pokaż więcej
Źródło :
Research in veterinary science [Res Vet Sci] 2021 Jul; Vol. 137, pp. 235-242. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article
MeSH Terms :
Nanoparticles*
Anti-Inflammatory Agents, Non-Steroidal/*pharmacokinetics
Carbazoles/*pharmacokinetics
Drug Delivery Systems/*veterinary
Injections, Intra-Articular/*veterinary
Animals ; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage ; Carbazoles/administration & dosage ; Cartilage, Articular ; Male ; Rabbits
Czasopismo naukowe
Tytuł :
Successful rechallenge of alectinib after remission of severe alectinib-induced interstitial lung disease.
Autorzy :
Huang JR; Department of Chest Medicine, Taipei Veterans General Hospital, Taipei.
Chou CW; General Chest Medicine, Department of Chest Medicine, Taipei Veterans General Hospital, Taipei.
Chao HS; General Chest Medicine, Department of Chest Medicine, Taipei Veterans General Hospital, Taipei.
Pokaż więcej
Źródło :
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners [J Oncol Pharm Pract] 2021 Jul; Vol. 27 (5), pp. 1311-1314. Date of Electronic Publication: 2020 Oct 14.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Adenocarcinoma of Lung/*drug therapy
Carbazoles/*adverse effects
Lung Diseases, Interstitial/*chemically induced
Lung Neoplasms/*drug therapy
Piperidines/*adverse effects
Aged ; Carbazoles/administration & dosage ; Female ; Humans ; Piperidines/administration & dosage ; Protein Kinase Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Ionic Carbazole-Based Water-Soluble Two-Photon Photoinitiator and the Fabrication of Biocompatible 3D Hydrogel Scaffold.
Autorzy :
Gao W; Laboratory of Organic NanoPhotonics and CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Beijing 100190, P. R. China.; School of Future Technologies, University of Chinese Academy of Sciences, Yanqihu Campus, Huaibei Zhuang, Huaibei Town, Huairou District, Beijing 101407, P. R. China.
Chao H; Department of Chemistry, School of Materials Science and Chemical Engineering, Beijing Technology and Business University, No. 11 Fucheng Road, Beijing 100048, P. R. China.
Zheng YC; Laboratory of Organic NanoPhotonics and CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Beijing 100190, P. R. China.
Zhang WC; Laboratory of Organic NanoPhotonics and CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Beijing 100190, P. R. China.; School of Future Technologies, University of Chinese Academy of Sciences, Yanqihu Campus, Huaibei Zhuang, Huaibei Town, Huairou District, Beijing 101407, P. R. China.
Liu J; Laboratory of Organic NanoPhotonics and CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Beijing 100190, P. R. China.
Jin F; Laboratory of Organic NanoPhotonics and CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Beijing 100190, P. R. China.
Dong XZ; Laboratory of Organic NanoPhotonics and CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Beijing 100190, P. R. China.
Liu YH; Laboratory of Organic NanoPhotonics and CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Beijing 100190, P. R. China.
Li SJ; Department of Chemistry, School of Materials Science and Chemical Engineering, Beijing Technology and Business University, No. 11 Fucheng Road, Beijing 100048, P. R. China.
Zheng ML; Laboratory of Organic NanoPhotonics and CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, No. 29 Zhongguancun East Road, Beijing 100190, P. R. China.; School of Future Technologies, University of Chinese Academy of Sciences, Yanqihu Campus, Huaibei Zhuang, Huaibei Town, Huairou District, Beijing 101407, P. R. China.
Pokaż więcej
Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Jun 23; Vol. 13 (24), pp. 27796-27805. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article
MeSH Terms :
Carbazoles/*chemistry
Hydrogels/*chemistry
Tissue Scaffolds/*chemistry
Animals ; Bridged-Ring Compounds/chemical synthesis ; Bridged-Ring Compounds/chemistry ; Bridged-Ring Compounds/toxicity ; Carbazoles/chemical synthesis ; Carbazoles/radiation effects ; Carbazoles/toxicity ; Cell Line ; Elastic Modulus ; Hydrogels/chemical synthesis ; Hydrogels/radiation effects ; Hydrogels/toxicity ; Imidazoles/chemical synthesis ; Imidazoles/chemistry ; Imidazoles/toxicity ; Mice ; Photons ; Polymerization/radiation effects ; Solubility ; Tissue Engineering/methods ; Water/chemistry
Czasopismo naukowe
Tytuł :
NMR characterization of rearranged staurosporine aglycone analogues from the marine sponge Damiria sp.
Autorzy :
Tran TD; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD.
Cartner LK; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD.; Basic Science Program, Leidos Biomedical Research, Inc., National Cancer Institute-Frederick National Laboratory for Cancer Research, Frederick, MD.
Bokesch HR; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD.; Basic Science Program, Leidos Biomedical Research, Inc., National Cancer Institute-Frederick National Laboratory for Cancer Research, Frederick, MD.
Henrich CJ; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD.; Basic Science Program, Leidos Biomedical Research, Inc., National Cancer Institute-Frederick National Laboratory for Cancer Research, Frederick, MD.
Wang XW; Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD.
Mahidol C; Chulabhorn Research Institute, Office of Research, Laboratory of Natural Products, Bangkok, Thailand.; Chulabhorn Graduate Institute, Chemical Biology Program, Chulabhorn Royal Academy, Bangkok, Thailand.
Ruchirawat S; Chulabhorn Research Institute, Office of Research, Laboratory of Natural Products, Bangkok, Thailand.; Chulabhorn Graduate Institute, Chemical Biology Program, Chulabhorn Royal Academy, Bangkok, Thailand.; Center of Excellence on Environmental Health and Toxicology (EHT), CHE, Ministry of Education, Bangkok, Thailand.
Kittakoop P; Chulabhorn Research Institute, Office of Research, Laboratory of Natural Products, Bangkok, Thailand.; Chulabhorn Graduate Institute, Chemical Biology Program, Chulabhorn Royal Academy, Bangkok, Thailand.; Center of Excellence on Environmental Health and Toxicology (EHT), CHE, Ministry of Education, Bangkok, Thailand.
O'Keefe BR; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD.
Gustafson KR; Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, MD.
Pokaż więcej
Źródło :
Magnetic resonance in chemistry : MRC [Magn Reson Chem] 2021 May; Vol. 59 (5), pp. 534-539. Date of Electronic Publication: 2019 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antineoplastic Agents/*pharmacology
Biological Products/*pharmacology
Carbazoles/*pharmacology
Indole Alkaloids/*pharmacology
Porifera/*chemistry
Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Biological Products/chemistry ; Biological Products/isolation & purification ; Carbazoles/chemistry ; Carbazoles/isolation & purification ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Indole Alkaloids/chemistry ; Indole Alkaloids/isolation & purification ; Magnetic Resonance Spectroscopy ; Molecular Conformation ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Design, synthesis and evaluation of carbazole derivatives as potential antimicrobial agents.
Autorzy :
Xue YJ; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University, Yanji, China.; School of Pharmacy, Fudan University, Shanghai, China.
Li MY; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University, Yanji, China.
Jin XJ; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University, Yanji, China.
Zheng CJ; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University, Yanji, China.
Piao HR; Key Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, Yanbian University, Yanji, China.
Pokaż więcej
Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 295-306.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*chemical synthesis
Bacterial Proteins/*chemistry
Carbazoles/*chemical synthesis
Enzyme Inhibitors/*chemical synthesis
Escherichia coli/*drug effects
Tetrahydrofolate Dehydrogenase/*chemistry
Anti-Infective Agents/pharmacology ; Bacterial Proteins/antagonists & inhibitors ; Bacterial Proteins/metabolism ; Binding Sites ; Candida albicans/drug effects ; Candida albicans/enzymology ; Candida albicans/growth & development ; Carbazoles/pharmacology ; Cell Line ; Cell Line, Tumor ; Enzyme Inhibitors/pharmacology ; Epithelial Cells/drug effects ; Escherichia coli/enzymology ; Escherichia coli/growth & development ; Guanidines/chemistry ; Hepatocytes/drug effects ; Humans ; Inhibitory Concentration 50 ; Isonicotinic Acids/chemistry ; Methicillin-Resistant Staphylococcus aureus/drug effects ; Methicillin-Resistant Staphylococcus aureus/enzymology ; Methicillin-Resistant Staphylococcus aureus/growth & development ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Protein Binding ; Protein Conformation ; Protein Interaction Domains and Motifs ; Semicarbazides/chemistry ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/enzymology ; Staphylococcus aureus/growth & development ; Streptococcus mutans/drug effects ; Streptococcus mutans/enzymology ; Streptococcus mutans/growth & development ; Structure-Activity Relationship ; Tetrahydrofolate Dehydrogenase/metabolism ; Triazines/chemistry
Czasopismo naukowe
Tytuł :
The effect of Gö6976 on chronic myeloid leukemia in vitro and in vivo.
Autorzy :
Cao ZR; The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, People's Republic of China.
Chen XP; The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, People's Republic of China.
Feng M; Neuroscience Research Center, Chongqing Medical University, Chongqing, People's Republic of China.
Hou YL; Zhoukou Union Osteological Hospital, Zhoukou, People's Republic of China.
Li Y; The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, People's Republic of China.
Hu XL; Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, School of Laboratory Medicine, Chongqing Medical University, Chongqing, People's Republic of China.
Huang ZL; Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, School of Laboratory Medicine, Chongqing Medical University, Chongqing, People's Republic of China.
Hu J; Key Laboratory of Laboratory Medical Diagnostics Designated by the Ministry of Education, School of Laboratory Medicine, Chongqing Medical University, Chongqing, People's Republic of China.
Pokaż więcej
Źródło :
Hematology (Amsterdam, Netherlands) [Hematology] 2021 Dec; Vol. 26 (1), pp. 543-551.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Carbazoles/*pharmacology
Cell Proliferation/*drug effects
Imatinib Mesylate/*pharmacology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*drug therapy
Animals ; Carbazoles/agonists ; Drug Agonism ; Humans ; Imatinib Mesylate/agonists ; K562 Cells ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred NOD ; Mice, SCID ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Exploring the Interaction of Curaxin CBL0137 with G-Quadruplex DNA Oligomers.
Autorzy :
Dallavalle S; Department of Food, Environmental and Nutritional Sciences (DEFENS), University of Milan (Università degli Studi di Milano), 20133 Milan, Italy.; National Institute of Fundamental Studies, Kandy 20000, Sri Lanka.
Mattio LM; Department of Food, Environmental and Nutritional Sciences (DEFENS), University of Milan (Università degli Studi di Milano), 20133 Milan, Italy.
Artali R; Scientia Advice di Roberto Artali, 20832 Desio, Italy.
Musso L; Department of Food, Environmental and Nutritional Sciences (DEFENS), University of Milan (Università degli Studi di Milano), 20133 Milan, Italy.
Aviñó A; Institute for Advanced Chemistry of Catalonia (IQAC), CSIC, Networking Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 08034 Barcelona, Spain.
Fàbrega C; Institute for Advanced Chemistry of Catalonia (IQAC), CSIC, Networking Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 08034 Barcelona, Spain.
Eritja R; Institute for Advanced Chemistry of Catalonia (IQAC), CSIC, Networking Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), 08034 Barcelona, Spain.
Gargallo R; Department of Chemical Engineering and Analytical Chemistry, University of Barcelona, 08028 Barcelona, Spain.
Mazzini S; Department of Food, Environmental and Nutritional Sciences (DEFENS), University of Milan (Università degli Studi di Milano), 20133 Milan, Italy.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 17; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
G-Quadruplexes*/drug effects
Carbazoles/*chemistry
DNA/*chemistry
Macromolecular Substances/*chemistry
Carbazoles/pharmacology ; DNA/metabolism ; Humans ; Macromolecular Substances/metabolism ; Magnetic Resonance Spectroscopy ; Molecular Conformation ; Molecular Structure ; Structure-Activity Relationship ; Telomere/genetics ; Telomere/metabolism
Czasopismo naukowe
Tytuł :
The ALK inhibitors, alectinib and ceritinib, induce ALK-independent and STAT3-dependent glioblastoma cell death.
Autorzy :
Kawauchi D; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Neurological Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Takahashi M; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.
Satomi K; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.
Yamamuro S; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan.
Kobayashi T; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan.
Uchida E; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, Hidaka-City, Japan.
Honda-Kitahara M; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.
Narita Y; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.
Iwadate Y; Department of Neurological Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Ichimura K; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.
Tomiyama A; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Neurosurgery, National Defense Medical College, Tokorozawa, Japan.
Pokaż więcej
Źródło :
Cancer science [Cancer Sci] 2021 Jun; Vol. 112 (6), pp. 2442-2453. Date of Electronic Publication: 2021 May 01.
Typ publikacji :
Journal Article
MeSH Terms :
Anaplastic Lymphoma Kinase/*genetics
Brain Neoplasms/*drug therapy
Carbazoles/*administration & dosage
Glioblastoma/*drug therapy
Piperidines/*administration & dosage
Pyrimidines/*administration & dosage
STAT3 Transcription Factor/*metabolism
Sulfones/*administration & dosage
Administration, Oral ; Anaplastic Lymphoma Kinase/metabolism ; Animals ; Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Carbazoles/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Resistance, Neoplasm/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Glioblastoma/genetics ; Glioblastoma/metabolism ; Humans ; Mice ; Piperidines/pharmacology ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/pharmacology ; Pyrimidines/pharmacology ; Signal Transduction/drug effects ; Sulfones/pharmacology ; Temozolomide/pharmacology ; Treatment Outcome ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Luminescence feature of new 3,6-di(thiazolidin-5-one-2-yl)-carbazole derivative: synthesis, photophysical properties, density functional theory studies, and crystal shape effect.
Autorzy :
Bawazeer TM; Department of Chemistry, College of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Althagafi I; Department of Chemistry, College of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Morad M; Department of Chemistry, College of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Munshi AM; Department of Chemistry, College of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Bayazeed AA; Department of Chemistry, College of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Alharbi A; Department of Chemistry, College of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
El-Metwaly N; Department of Chemistry, College of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.; Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Pokaż więcej
Źródło :
Luminescence : the journal of biological and chemical luminescence [Luminescence] 2021 Jun; Vol. 36 (4), pp. 904-913. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji :
Journal Article
MeSH Terms :
Carbazoles*
Luminescence*
Density Functional Theory ; Solvents ; Spectrometry, Fluorescence
Czasopismo naukowe
Tytuł :
Structure-based discovery of SIAIS001 as an oral bioavailability ALK degrader constructed from Alectinib.
Autorzy :
Ren C; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Sun N; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China.
Kong Y; Jing Medicine Technology (Shanghai), Ltd., Y building230 Haike Road, Shanghai, 201210, China.
Qu X; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
Liu H; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; School of Physical Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Zhong H; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; Changzhou University, Changzhou, Jiangsu, 213164, China.
Song X; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China. Electronic address: .
Yang X; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China. Electronic address: .
Jiang B; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai, 201210, China; CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China. Electronic address: .
Pokaż więcej
Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 May 05; Vol. 217, pp. 113335. Date of Electronic Publication: 2021 Mar 11.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Discovery*
Anaplastic Lymphoma Kinase/*antagonists & inhibitors
Antineoplastic Agents/*pharmacology
Carbazoles/*pharmacology
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Neoplasms/*drug therapy
Piperidines/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Administration, Oral ; Anaplastic Lymphoma Kinase/metabolism ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/chemistry ; Biological Availability ; Carbazoles/chemistry ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Molecular Structure ; Piperidines/chemistry ; Protein Kinase Inhibitors/administration & dosage ; Protein Kinase Inhibitors/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Synthesis and biological evaluation of pyranocarbazole derivatives as Anti-tumor agents.
Autorzy :
Liu K; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Zang Y; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Shen C; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Li C; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Ma J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Yang J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Sun X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Chen X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Wang N; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Zhang D; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. Electronic address: .
Pokaż więcej
Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Feb 01; Vol. 33, pp. 127739. Date of Electronic Publication: 2020 Dec 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Carbazoles/*pharmacology
Pyrans/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Carbazoles/chemical synthesis ; Carbazoles/chemistry ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Pyrans/chemical synthesis ; Pyrans/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Structure-activity relationship (SAR) studies on the mutagenic properties of 2,7-diaminofluorene and 2,7-diaminocarbazole derivatives.
Autorzy :
Kim BW; Department of Chemistry, College of Natural Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea.
Lee H; Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 02792, Republic of Korea.
Keum G; Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 02792, Republic of Korea. Electronic address: .
Kim BM; Department of Chemistry, College of Natural Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea. Electronic address: .
Pokaż więcej
Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jan 01; Vol. 31, pp. 127662. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*pharmacology
Carbazoles/*pharmacology
Fluorenes/*pharmacology
Salmonella typhimurium/*drug effects
Viral Nonstructural Proteins/*antagonists & inhibitors
Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Carbazoles/chemical synthesis ; Carbazoles/chemistry ; Dose-Response Relationship, Drug ; Fluorenes/chemical synthesis ; Fluorenes/chemistry ; Molecular Docking Simulation ; Molecular Structure ; Mutagenicity Tests ; Salmonella typhimurium/genetics ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer Cells.
Autorzy :
Luparello C; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, Edificio 16, 90128 Palermo, Italy.
Cruciata I; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, Edificio 16, 90128 Palermo, Italy.
Joerger AC; Institute of Pharmaceutical Chemistry, Goethe University, 60438 Frankfurt am Main, Germany.; Buchmann Institute for Molecular Life Sciences, Structural Genomics Consortium (SGC), 60438 Frankfurt am Main, Germany.
Ocasio CA; Department of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK.
Jones R; Department of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK.
Tareque RK; Department of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK.
Bagley MC; Department of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK.
Spencer J; Department of Chemistry, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK.
Walker M; Eurofins Integrated Discovery UK Ltd., Fyfield Business & Research Park, Fyfield Road, Ongar, Essex CM5 0GS, UK.
Austin C; Eurofins Integrated Discovery UK Ltd., Fyfield Business & Research Park, Fyfield Road, Ongar, Essex CM5 0GS, UK.
Ferrara T; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, Edificio 16, 90128 Palermo, Italy.
D Oca P; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, Edificio 16, 90128 Palermo, Italy.
Bellina R; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, Edificio 16, 90128 Palermo, Italy.
Branni R; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, Edificio 16, 90128 Palermo, Italy.
Caradonna F; Department of Biological Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, Edificio 16, 90128 Palermo, Italy.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 26; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Breast Neoplasms/*metabolism
Carbazoles/*pharmacology
Mutagens/*pharmacology
Antineoplastic Agents/chemistry ; Breast Neoplasms/genetics ; Carbazoles/chemistry ; DNA Damage ; DNA Methylation ; Epigenesis, Genetic/drug effects ; Female ; Histones/metabolism ; Humans ; MCF-7 Cells ; Mutagens/chemistry ; Signal Transduction ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies