Temat: "Carbon Tetrachloride Poisoning" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Honokiol Acts as a Potent Anti-Fibrotic Agent in the Liver through Inhibition of TGF-β1/SMAD Signaling and Autophagy in Hepatic Stellate Cells.
Autorzy:: Kataoka S; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Umemura A; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Okuda K; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Taketani H; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Seko Y; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Nishikawa T; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Yamaguchi K; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Moriguchi M; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.
Kanbara Y; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita 564-0013, Japan.
Arbiser JL; Department of Dermatology, Emory University School of Medicine, Atlanta, GA 30322, USA.; Veterans Affairs Medical Center, Decatur, GA 30322, USA.
Shima T; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita 564-0013, Japan.
Okanoue T; Department of Gastroenterology and Hepatology, Saiseikai Suita Hospital, Suita 564-0013, Japan.
Itoh Y; Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 12; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 12.
Typ publikacji:: Journal Article
MeSH Terms:: Carbon Tetrachloride Poisoning*/drug therapy
Carbon Tetrachloride Poisoning*/metabolism
Carbon Tetrachloride Poisoning*/pathology
Hepatic Stellate Cells*/metabolism
Hepatic Stellate Cells*/pathology
Liver Cirrhosis*/metabolism
Liver Cirrhosis*/pathology
Autophagy/*drug effects
Biphenyl Compounds/*pharmacology
Lignans/*pharmacology
Liver/*metabolism
Signal Transduction/*drug effects
Smad Proteins/*metabolism
Transforming Growth Factor beta1/*metabolism
Animals ; Liver/pathology ; Male ; Mice

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Skocz do pozycji: 2.

Tytuł:: Eritoran Attenuates Hepatic Inflammation and Fibrosis in Mice with Chronic Liver Injury.
Autorzy:: Hsieh YC; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.; Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11217, Taiwan.; Institute of Pharmacology, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11217, Taiwan.
Lee KC; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.; Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11217, Taiwan.
Wu PS; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.; Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11217, Taiwan.
Huo TI; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.; Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11217, Taiwan.; Institute of Pharmacology, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11217, Taiwan.
Huang YH; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.; Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11217, Taiwan.
Hou MC; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.; Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11217, Taiwan.
Lin HC; Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.; Department of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei 11217, Taiwan.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Jun 21; Vol. 10 (6). Date of Electronic Publication: 2021 Jun 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carbon Tetrachloride Poisoning*/drug therapy
Carbon Tetrachloride Poisoning*/metabolism
End Stage Liver Disease*/chemically induced
End Stage Liver Disease*/drug therapy
End Stage Liver Disease*/metabolism
Liver Cirrhosis*/chemically induced
Liver Cirrhosis*/drug therapy
Liver Cirrhosis*/metabolism
Disaccharides/*pharmacology
Sugar Phosphates/*pharmacology
Animals ; Hepatic Stellate Cells/metabolism ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/pathology ; Kupffer Cells/metabolism ; MAP Kinase Signaling System/drug effects ; Male ; Mice ; Transcription Factor RelA/metabolism ; Transforming Growth Factor beta1/metabolism

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Skocz do pozycji: 3.

Tytuł:: Macrophage potentiates the recovery of liver zonation and metabolic function after acute liver injury.
Autorzy:: Miura A; General Research Institute, Nihon University Collage of Bioresource Sciences, Fujisawa, Kanagawa, 252-0880, Japan.
Hosono T; Department of Applied Life Sciences, Nihon University Graduate School of Bioresource Sciences, Fujisawa, Kanagawa, 252-0880, Japan.; Department of Chemistry and Life Science, Nihon University Collage of Bioresource Sciences, Fujisawa, Kanagawa, 252-0880, Japan.
Seki T; General Research Institute, Nihon University Collage of Bioresource Sciences, Fujisawa, Kanagawa, 252-0880, Japan. .; Department of Applied Life Sciences, Nihon University Graduate School of Bioresource Sciences, Fujisawa, Kanagawa, 252-0880, Japan. .; Department of Chemistry and Life Science, Nihon University Collage of Bioresource Sciences, Fujisawa, Kanagawa, 252-0880, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 May 06; Vol. 11 (1), pp. 9730. Date of Electronic Publication: 2021 May 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carbon Tetrachloride Poisoning/*immunology
Chemical and Drug Induced Liver Injury/*immunology
Liver/*immunology
Macrophages/*immunology
Amino Acids, Branched-Chain/blood ; Animals ; Carbon Tetrachloride Poisoning/metabolism ; Carbon Tetrachloride Poisoning/physiopathology ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury/physiopathology ; Clodronic Acid/administration & dosage ; Liver/metabolism ; Liver/physiopathology ; Liver Regeneration/drug effects ; Mice ; Mice, Inbred C57BL

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Skocz do pozycji: 4.

Tytuł:: Targeting ROS/NF-κB sigaling pathway by the seedless black Vitis vinifera polyphenols in CCl 4 -intoxicated kidney, lung, brain, and spleen in rats.
Autorzy:: Habashy NH; Biochemistry Department, Faculty of Science, Alexandria University, Alexandria, 21511, Egypt. .
Kodous AS; Radiation Biology Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt.
Abu-Serie MM; Department of Medical Biotechnology, Genetic Engineering, and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg EL-Arab, Alexandria, 21934, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Aug 16; Vol. 11 (1), pp. 16575. Date of Electronic Publication: 2021 Aug 16.
Typ publikacji:: Comparative Study; Journal Article
MeSH Terms:: Phytotherapy*
Anti-Inflammatory Agents/*therapeutic use
Antioxidants/*therapeutic use
Carbon Tetrachloride Poisoning/*drug therapy
NF-kappa B/*antagonists & inhibitors
Polyphenols/*therapeutic use
Reactive Oxygen Species/*antagonists & inhibitors
Vitis/*chemistry
Animals ; Anti-Inflammatory Agents/isolation & purification ; Antioxidants/isolation & purification ; Brain/drug effects ; Brain/metabolism ; Carbon Tetrachloride Poisoning/metabolism ; Cyclooxygenase 2/biosynthesis ; Cyclooxygenase 2/genetics ; Cytokines/biosynthesis ; Cytokines/genetics ; Drug Evaluation, Preclinical ; Fruit/chemistry ; Inhibitory Concentration 50 ; Kidney/drug effects ; Kidney/metabolism ; Lung/drug effects ; Lung/metabolism ; Nitric Oxide Synthase Type II/biosynthesis ; Nitric Oxide Synthase Type II/genetics ; Oxidative Stress/drug effects ; Plant Extracts/isolation & purification ; Polyphenols/chemistry ; Polyphenols/isolation & purification ; Rats ; Signal Transduction/drug effects ; Spleen/drug effects ; Spleen/metabolism ; Thiobarbituric Acid Reactive Substances/analysis

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Skocz do pozycji: 5.

Tytuł:: Schisandrin B suppresses liver fibrosis in rats by targeting miR-101-5p through the TGF-β signaling pathway.
Autorzy:: Cuiqiong W; Key Laboratory Breeding Base of Hunan Oriented Fundamental and Applied Research of Innovative Pharmaceutics, Department of Basic Medical Science, Changsha Medical University, Changsha, China.
Chao X; Key Laboratory Breeding Base of Hunan Oriented Fundamental and Applied Research of Innovative Pharmaceutics, Department of Basic Medical Science, Changsha Medical University, Changsha, China.
Xinling F; Key Laboratory Breeding Base of Hunan Oriented Fundamental and Applied Research of Innovative Pharmaceutics, Department of Basic Medical Science, Changsha Medical University, Changsha, China.
Yinyan J; Key Laboratory Breeding Base of Hunan Oriented Fundamental and Applied Research of Innovative Pharmaceutics, Department of Basic Medical Science, Changsha Medical University, Changsha, China.; Pokaż więcej
Źródło:: Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2020 Dec; Vol. 48 (1), pp. 473-478.
Typ publikacji:: Journal Article; Video-Audio Media
MeSH Terms:: Carbon Tetrachloride Poisoning*/drug therapy
Carbon Tetrachloride Poisoning*/metabolism
Carbon Tetrachloride Poisoning*/pathology
Liver Cirrhosis*/chemically induced
Liver Cirrhosis*/drug therapy
Liver Cirrhosis*/metabolism
Liver Cirrhosis*/pathology
Lignans/*pharmacology
MicroRNAs/*metabolism
Polycyclic Compounds/*pharmacology
Signal Transduction/*drug effects
Transforming Growth Factor beta/*metabolism
Animals ; Cyclooctanes/pharmacology ; Humans ; Male ; Rats ; Rats, Sprague-Dawley

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Skocz do pozycji: 6.

Tytuł:: Chronic Carbon Tetrachloride Applications Induced Hepatocyte Apoptosis in Lipocalin 2 Null Mice Through Endoplasmic Reticulum Stress and Unfolded Protein Response.
Autorzy:: Borkham-Kamphorst E; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, RWTH Aachen University Hospital, D-52074 Aachen, Germany.
Haas U; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, RWTH Aachen University Hospital, D-52074 Aachen, Germany.
Van de Leur E; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, RWTH Aachen University Hospital, D-52074 Aachen, Germany.
Trevanich A; Department of Statistics, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
Weiskirchen R; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry, RWTH Aachen University Hospital, D-52074 Aachen, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 23; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 23.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*/drug effects
Apoptosis*/genetics
Endoplasmic Reticulum Stress*/drug effects
Endoplasmic Reticulum Stress*/genetics
Unfolded Protein Response*/drug effects
Unfolded Protein Response*/genetics
Carbon Tetrachloride/*toxicity
Carbon Tetrachloride Poisoning/*metabolism
Hepatocytes/*metabolism
Lipocalin-2/*deficiency
Animals ; Carbon Tetrachloride Poisoning/genetics ; Carbon Tetrachloride Poisoning/pathology ; Hepatocytes/pathology ; Lipocalin-2/metabolism ; Lipogenesis/drug effects ; Lipogenesis/genetics ; Mice ; Mice, Knockout ; Signal Transduction/drug effects ; Signal Transduction/genetics

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Skocz do pozycji: 7.

Tytuł:: Hepatic stellate cell hypertrophy is associated with metabolic liver fibrosis.
Autorzy:: Hoffmann C; Université Paris Descartes, UTCBS, CNRS, INSERM, F-75006, Paris, France. .
Djerir NEH; Université Paris Descartes, UTCBS, CNRS, INSERM, F-75006, Paris, France.
Danckaert A; Institut Pasteur, C2RT, UTechS Photonic BioImaging, Paris, France.
Fernandes J; Institut Pasteur, C2RT, UTechS Photonic BioImaging, Paris, France.
Roux P; Institut Pasteur, C2RT, UTechS Photonic BioImaging, Paris, France.
Charrueau C; Université Paris Descartes, UTCBS, CNRS, INSERM, F-75006, Paris, France.
Lachagès AM; Université Paris Descartes, UTCBS, CNRS, INSERM, F-75006, Paris, France.
Charlotte F; Service d'Anatomie et Cytologie Pathologiques, Hôpitaux universitaires Pitié-Salpêtrière-Charles Foix (AP-HP), F-75013, Paris, France.
Brocheriou I; Service d'Anatomie et Cytologie Pathologiques, Hôpitaux universitaires Pitié-Salpêtrière-Charles Foix (AP-HP), F-75013, Paris, France.
Clément K; Sorbonne Université, Inserm, UMRS NutriOmique, Service de Nutrition, Hôpitaux universitaires Pitié-Salpêtrière-Charles Foix, F-75013, Paris, France.
Aron-Wisnewsky J; Sorbonne Université, Inserm, UMRS NutriOmique, Service de Nutrition, Hôpitaux universitaires Pitié-Salpêtrière-Charles Foix, F-75013, Paris, France.
Foufelle F; INSERM, Sorbonne Université, Université de Paris; Centre de Recherche des Cordeliers, F-75006, Paris, France.
Ratziu V; INSERM, Sorbonne Université, Université de Paris; Centre de Recherche des Cordeliers, F-75006, Paris, France.; Sorbonne Université, Institute for Cardiometabolism and Nutrition, Hôpital Pitié Salpêtrière, Assistance Publique Hôpitaux de Paris, Paris, France.
Hainque B; Université Paris Descartes, UTCBS, CNRS, INSERM, F-75006, Paris, France.; Service de Biochimie métabolique, Hôpitaux universitaires Pitié-Salpêtrière-Charles Foix (AP-HP), F-75013, Paris, France.
Bonnefont-Rousselot D; Université Paris Descartes, UTCBS, CNRS, INSERM, F-75006, Paris, France.; Service de Biochimie métabolique, Hôpitaux universitaires Pitié-Salpêtrière-Charles Foix (AP-HP), F-75013, Paris, France.
Bigey P; Université Paris Descartes, UTCBS, CNRS, INSERM, F-75006, Paris, France.; Chimie ParisTech, PSL Research University, UTCBS, F-75005, Paris, France.
Escriou V; Université Paris Descartes, UTCBS, CNRS, INSERM, F-75006, Paris, France.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Mar 02; Vol. 10 (1), pp. 3850. Date of Electronic Publication: 2020 Mar 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carbon Tetrachloride Poisoning*/metabolism
Carbon Tetrachloride Poisoning*/pathology
Hepatic Stellate Cells*/metabolism
Hepatic Stellate Cells*/pathology
Liver Cirrhosis*/chemically induced
Liver Cirrhosis*/metabolism
Liver Cirrhosis*/pathology
Dietary Fats/*adverse effects
Animals ; Dietary Fats/pharmacology ; Humans ; Male ; Mice

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Skocz do pozycji: 8.

Tytuł:: Assessment of the hepatoprotective effect of developed lipid-polymer hybrid nanoparticles (LPHNPs) encapsulating naturally extracted β-Sitosterol against CCl 4 induced hepatotoxicity in rats.
Autorzy:: Abdou EM; Department of Pharmaceutics, National organization of Drug control and Research (NODCAR), Giza, Egypt. .; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, MTI University, Cairo, Egypt. .
Fayed MAA; Department of Pharmacognosy, Faculty of Pharmacy, University of Sadat City, Sadat City, Egypt.
Helal D; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, El-Fayoum University, El-Fayoum, Egypt.
Ahmed KA; Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Dec 24; Vol. 9 (1), pp. 19779. Date of Electronic Publication: 2019 Dec 24.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants*/chemistry
Antioxidants*/pharmacology
Carbon Tetrachloride Poisoning*/drug therapy
Carbon Tetrachloride Poisoning*/metabolism
Carbon Tetrachloride Poisoning*/pathology
Nanoparticles*/chemistry
Sitosterols*/chemistry
Sitosterols*/pharmacology
Liver/*metabolism
Animals ; Centaurea/chemistry ; Lipids/chemistry ; Lipids/pharmacology ; Liver/pathology ; Male ; Polyesters/chemistry ; Polyesters/pharmacology ; Polyethylene Glycols/chemistry ; Polyethylene Glycols/pharmacology ; Rats

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Skocz do pozycji: 9.

Tytuł:: Co-administration of resveratrol and beta-aminopropionitrile attenuates liver fibrosis development via targeting lysyl oxidase in CCl 4 -induced liver fibrosis in rats.
Autorzy:: Mohseni R; Department of Clinical Biochemistry, Hamadan University of Medical Sciences, Hamadan, Iran.
Arab Sadeghabadi Z; Department of Clinical Biochemistry, Hamadan University of Medical Sciences, Hamadan, Iran.
Goodarzi MT; Department of Biochemistry, Islamic Azad University, Shahrood Branch, Shahrood, Iran.
Karimi J; Department of Clinical Biochemistry, Hamadan University of Medical Sciences, Hamadan, Iran.; Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.; Pokaż więcej
Źródło:: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2019 Dec; Vol. 41 (6), pp. 644-651. Date of Electronic Publication: 2019 Nov 14.
Typ publikacji:: Journal Article
MeSH Terms:: Drug Delivery Systems*
Aminopropionitrile/*pharmacology
Carbon Tetrachloride Poisoning/*drug therapy
Liver Cirrhosis/*drug therapy
Protein-Lysine 6-Oxidase/*immunology
Resveratrol/*pharmacology
Animals ; Carbon Tetrachloride Poisoning/immunology ; Carbon Tetrachloride Poisoning/pathology ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/immunology ; Liver Cirrhosis/pathology ; Male ; Rats ; Rats, Wistar

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Skocz do pozycji: 10.

Tytuł:: Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model.
Autorzy:: Park MR; Hans Schöler Stem Cell Research Center (HSSCRC), School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.
Wong MS; Hans Schöler Stem Cell Research Center (HSSCRC), School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.
Araúzo-Bravo MJ; Group of Computational Biology and Bioinformatics, Biodonostia Health Research Institute, San Sebastián, and IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.
Lee H; Hans Schöler Stem Cell Research Center (HSSCRC), School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.
Nam D; Hans Schöler Stem Cell Research Center (HSSCRC), School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.
Park SY; Hans Schöler Stem Cell Research Center (HSSCRC), School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.
Seo HD; Hans Schöler Stem Cell Research Center (HSSCRC), School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.
Lee SM; Hans Schöler Stem Cell Research Center (HSSCRC), School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.
Zeilhofer HF; Department of Cranio-Maxillofacial Surgery, University Hospital Basel, Basel, Switzerland.
Zaehres H; Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Schöler HR; Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Kim JB; Hans Schöler Stem Cell Research Center (HSSCRC), School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Aug 12; Vol. 14 (8), pp. e0221085. Date of Electronic Publication: 2019 Aug 12 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carbon Tetrachloride Poisoning*/genetics
Carbon Tetrachloride Poisoning*/metabolism
Carbon Tetrachloride Poisoning*/therapy
Hepatocyte Nuclear Factor 4*/genetics
Hepatocyte Nuclear Factor 4*/metabolism
Induced Pluripotent Stem Cells*/metabolism
Induced Pluripotent Stem Cells*/pathology
Induced Pluripotent Stem Cells*/transplantation
Liver*/metabolism
Liver*/pathology
Liver Cirrhosis*/chemically induced
Liver Cirrhosis*/genetics
Liver Cirrhosis*/metabolism
Liver Cirrhosis*/therapy
Lung Injury*/chemically induced
Lung Injury*/genetics
Lung Injury*/metabolism
Octamer Transcription Factor-3*/genetics
Octamer Transcription Factor-3*/metabolism
Stem Cell Transplantation*
Animals ; Male ; Mice

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Skocz do pozycji: 11.

Tytuł:: Paeonol alleviates CCl 4 -induced liver fibrosis through suppression of hepatic stellate cells activation via inhibiting the TGF-β/Smad3 signaling.
Autorzy:: Wu S; a Department of Anatomy , Chongqing Medical University , Chongqing , People's Republic of China.
Liu L; b Department of Medical Laboratory , Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders , Chongqing , People's Republic of China.
Yang S; c Department of Pharmacology , Chongqing Medical University , Chongqing , People's Republic of China.
Kuang G; c Department of Pharmacology , Chongqing Medical University , Chongqing , People's Republic of China.
Yin X; d Department of Gastroenterology , Institute of Surgery Research, Daping Hospital, Third Military Medical University , Chongqing , People's Republic of China.
Wang Y; c Department of Pharmacology , Chongqing Medical University , Chongqing , People's Republic of China.
Xu F; c Department of Pharmacology , Chongqing Medical University , Chongqing , People's Republic of China.
Xiong L; c Department of Pharmacology , Chongqing Medical University , Chongqing , People's Republic of China.
Zhang M; c Department of Pharmacology , Chongqing Medical University , Chongqing , People's Republic of China.
Wan J; c Department of Pharmacology , Chongqing Medical University , Chongqing , People's Republic of China.
Gong X; a Department of Anatomy , Chongqing Medical University , Chongqing , People's Republic of China.; Pokaż więcej
Źródło:: Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2019 Jun; Vol. 41 (3), pp. 438-445. Date of Electronic Publication: 2019 May 23.
Typ publikacji:: Journal Article
MeSH Terms:: Acetophenones/*pharmacology
Carbon Tetrachloride Poisoning/*drug therapy
Hepatic Stellate Cells/*immunology
Liver Cirrhosis/*drug therapy
Signal Transduction/*drug effects
Smad3 Protein/*immunology
Transforming Growth Factor beta/*immunology
Animals ; Carbon Tetrachloride Poisoning/immunology ; Carbon Tetrachloride Poisoning/pathology ; Hepatic Stellate Cells/pathology ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/immunology ; Liver Cirrhosis/pathology ; Male ; Mice ; Signal Transduction/immunology

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Skocz do pozycji: 12.

Tytuł:: TIM-4 interference in Kupffer cells against CCL4-induced liver fibrosis by mediating Akt1/Mitophagy signalling pathway.
Autorzy:: Wu H; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chen G; Department of Hepatobiliary and pancreatic surgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, People's Hospital of Henan University, Zhengzhou, China.
Wang J; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Deng M; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yuan F; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Gong J; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Pokaż więcej
Źródło:: Cell proliferation [Cell Prolif] 2020 Jan; Vol. 53 (1), pp. e12731. Date of Electronic Publication: 2019 Nov 22.
Typ publikacji:: Journal Article
MeSH Terms:: Carbon Tetrachloride Poisoning/*metabolism
Kupffer Cells/*metabolism
Liver Cirrhosis/*metabolism
Membrane Proteins/*metabolism
Mitophagy/*drug effects
Proto-Oncogene Proteins c-akt/*metabolism
Signal Transduction/*drug effects
Animals ; Carbon Tetrachloride/toxicity ; Carbon Tetrachloride Poisoning/pathology ; Disease Models, Animal ; Kupffer Cells/pathology ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/pathology ; Male ; Mice

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Skocz do pozycji: 13.

Tytuł:: Human bone marrow mesenchymal stem cells-derived exosomes alleviate liver fibrosis through the Wnt/β-catenin pathway.
Autorzy:: Rong X; Department of Clinical Laboratory, China-Japan Union Hospital of Jilin University, 126 Xiantai St., Changchun, 130033, Jilin, China.; The Scientific Research Center, China-Japan Union Hospital of Jilin University, 126 Xiantai St., Changchun, 130033, Jilin, China.
Liu J; Department of Quality Control, China-Japan Union Hospital of Jilin University, 126 Xiantai St., Changchun, 130033, Jilin, China.
Yao X; Department of Anesthesiology, Affiliated Hospital of Changchun University of Traditional Chinese Medicine, 1478 Gongnong Road, Changchun, 130117, Jilin, China.
Jiang T; Department of Cardiology, China-Japan Union Hospital of Jilin University, 126 Xiantai St., Changchun, 130033, Jilin, China.
Wang Y; The Scientific Research Center, China-Japan Union Hospital of Jilin University, 126 Xiantai St., Changchun, 130033, Jilin, China. .
Xie F; Department of Clinical Laboratory, China-Japan Union Hospital of Jilin University, 126 Xiantai St., Changchun, 130033, Jilin, China. .; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2019 Mar 18; Vol. 10 (1), pp. 98. Date of Electronic Publication: 2019 Mar 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carbon Tetrachloride Poisoning*/metabolism
Carbon Tetrachloride Poisoning*/pathology
Carbon Tetrachloride Poisoning*/therapy
Exosomes*/metabolism
Exosomes*/pathology
Exosomes*/transplantation
Liver Cirrhosis*/metabolism
Liver Cirrhosis*/pathology
Liver Cirrhosis*/therapy
Wnt Signaling Pathway*
Bone Marrow Cells/*metabolism
Mesenchymal Stem Cells/*metabolism
Animals ; Bone Marrow Cells/pathology ; Female ; Heterografts ; Humans ; Mesenchymal Stem Cells/pathology ; Rats ; Rats, Sprague-Dawley ; beta Catenin

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Skocz do pozycji: 14.

Tytuł:: Genome‑wide identification of long noncoding RNAs in CCl4‑induced liver fibrosis via RNA sequencing.
Autorzy:: Gong Z; Department of Ultrasound, Peking University Shenzhen Hospital, Shenzhen PKU‑HKUST Medical Center, Shenzhen, Guangdong 518036, P.R. China.
Tang J; Department of Public Health, Center for Disease Control and Prevention in Jiangxi, Nanchang, Jiangxi 330029, P.R. China.
Xiang T; Department of Infectious Diseases, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Lin J; Department of Digestive Diseases, The Eighth Affiliated Hospital of Sun Yat‑sen University, Shenzhen, Guangdong 518033, P.R. China.
Deng C; Department of Infectious Diseases, Peking University Shenzhen Hospital, Shenzhen PKU‑HKUST Medical Center, Shenzhen, Guangdong 518036, P.R. China.
Peng Y; Department of Infectious Diseases, Peking University Shenzhen Hospital, Shenzhen PKU‑HKUST Medical Center, Shenzhen, Guangdong 518036, P.R. China.
Zheng J; Department of Traditional Chinese Medicine, Peking University Shenzhen Hospital, Shenzhen PKU‑HKUST Medical Center, Shenzhen, Guangdong 518036, P.R. China.
Hu G; Department of Infectious Diseases, Peking University Shenzhen Hospital, Shenzhen PKU‑HKUST Medical Center, Shenzhen, Guangdong 518036, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2018 Jul; Vol. 18 (1), pp. 299-307. Date of Electronic Publication: 2018 May 07.
Typ publikacji:: Journal Article
MeSH Terms:: High-Throughput Nucleotide Sequencing*
Signal Transduction*
Carbon Tetrachloride Poisoning/*metabolism
Liver Cirrhosis/*metabolism
RNA, Long Noncoding/*biosynthesis
Animals ; Biomarkers/metabolism ; Carbon Tetrachloride Poisoning/genetics ; Genome-Wide Association Study ; Liver Cirrhosis/genetics ; Male ; RNA, Long Noncoding/genetics ; Rats ; Rats, Sprague-Dawley

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Skocz do pozycji: 15.

Tytuł:: Protective effect of Teucrium polium on carbon tetrachloride induced genotoxicity and oxidative stress in rats.
Autorzy:: Rahmouni F; a Laboratory of Histology , Medicine Faculty of Sfax University , Sfax , Tunisia.
Saoudi M; b Laboratory of Animal Physiology , Sciences Faculty of Sfax University , Sfax , Tunisia.
Amri N; a Laboratory of Histology , Medicine Faculty of Sfax University , Sfax , Tunisia.
El-Feki A; b Laboratory of Animal Physiology , Sciences Faculty of Sfax University , Sfax , Tunisia.
Rebai T; a Laboratory of Histology , Medicine Faculty of Sfax University , Sfax , Tunisia.
Badraoui R; a Laboratory of Histology , Medicine Faculty of Sfax University , Sfax , Tunisia.; c Laboratory of Histology , Medicine College of Tunis El-Manar University , Tunis , Tunisia.; Pokaż więcej
Źródło:: Archives of physiology and biochemistry [Arch Physiol Biochem] 2018 Feb; Vol. 124 (1), pp. 1-9. Date of Electronic Publication: 2017 Jul 16.
Typ publikacji:: Journal Article
MeSH Terms:: Carbon Tetrachloride Poisoning/*drug therapy
DNA Damage/*drug effects
Oxidative Stress/*drug effects
Plant Components, Aerial/*chemistry
Plant Extracts/*therapeutic use
Protective Agents/*therapeutic use
Teucrium/*chemistry
Animals ; Antioxidants/analysis ; Antioxidants/chemistry ; Antioxidants/therapeutic use ; Carbon Tetrachloride Poisoning/blood ; Carbon Tetrachloride Poisoning/metabolism ; Carbon Tetrachloride Poisoning/pathology ; Chromosome Aberrations/chemically induced ; Chromosome Aberrations/drug effects ; Erythrocytes/drug effects ; Erythrocytes/enzymology ; Erythrocytes/metabolism ; Ethnopharmacology ; Flavonoids/analysis ; Flavonoids/therapeutic use ; Lipid Peroxidation/drug effects ; Male ; Medicine, African Traditional ; Necrosis ; Plant Components, Aerial/growth & development ; Plant Extracts/chemistry ; Protective Agents/chemistry ; Random Allocation ; Rats, Wistar ; Sister Chromatid Exchange/drug effects ; Spleen/drug effects ; Spleen/metabolism ; Spleen/pathology ; Teucrium/growth & development ; Tunisia

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Skocz do pozycji: 16.

Tytuł:: Preliminary Characterization, Antioxidant and Hepatoprotective Activities of Polysaccharides from Taishan Pinus massoniana Pollen.
Autorzy:: Zhou C; College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. zcm_.
Yin S; College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. .; College of Veterinary Medicine, Yangzhou University, 12 East Wenhui Road, Yangzhou 225009, China. .
Yu Z; College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. .
Feng Y; College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. .
Wei K; College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. .
Ma W; College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. .
Ge L; College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. .
Yan Z; College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. .; Research Center for Animal Disease Control Engineering Shandong Province, Shandong Agricultural University, Tai'an 271018, China. .
Zhu R; College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an 271018, China. .; Research Center for Animal Disease Control Engineering Shandong Province, Shandong Agricultural University, Tai'an 271018, China. .; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2018 Jan 30; Vol. 23 (2). Date of Electronic Publication: 2018 Jan 30.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants*/chemistry
Antioxidants*/pharmacology
Polysaccharides*/chemistry
Polysaccharides*/pharmacology
Carbon Tetrachloride Poisoning/*prevention & control
Liver/*metabolism
Pinus/*chemistry
Pollen/*chemistry
Animals ; Carbon Tetrachloride Poisoning/metabolism ; Carbon Tetrachloride Poisoning/pathology ; Dose-Response Relationship, Drug ; Liver/pathology ; Male ; Rats ; Rats, Wistar

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Skocz do pozycji: 17.

Tytuł:: Vatalanib, a tyrosine kinase inhibitor, decreases hepatic fibrosis and sinusoidal capillarization in CCl4-induced fibrotic mice.
Autorzy:: Kong LJ; Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086, P.R. China.
Li H; Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086, P.R. China.
Du YJ; Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086, P.R. China.
Pei FH; Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086, P.R. China.
Hu Y; Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086, P.R. China.
Zhao LL; Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086, P.R. China.
Chen J; Department of Gastroenterology, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150086, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2017 May; Vol. 15 (5), pp. 2604-2610. Date of Electronic Publication: 2017 Mar 15.
Typ publikacji:: Journal Article
MeSH Terms:: Carbon Tetrachloride Poisoning*/drug therapy
Carbon Tetrachloride Poisoning*/metabolism
Carbon Tetrachloride Poisoning*/pathology
Liver Cirrhosis*/chemically induced
Liver Cirrhosis*/drug therapy
Liver Cirrhosis*/metabolism
Liver Cirrhosis*/pathology
Phthalazines/*pharmacology
Pyridines/*pharmacology
Animals ; Male ; Mice ; Mice, Inbred BALB C

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Skocz do pozycji: 18.

Tytuł:: Effects of Liver Fibrosis Progression on Tissue Relaxation Times in Different Mouse Models Assessed by Ultrahigh Field Magnetic Resonance Imaging.
Autorzy:: Müller A; Clinic for Diagnostic and Interventional Radiology, Saarland University Medical Center, Kirrberger Str. 100, Bdg. 50.1, 66421 Homburg, Germany.
Hochrath K; Department of Medicine, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA; Department of Internal Medicine II, Saarland University, Saarland University Medical Center, Bdg. 77, Kirrberger Str. 100, 66421 Homburg, Germany.
Stroeder J; Clinic for Diagnostic and Interventional Radiology, Saarland University Medical Center, Kirrberger Str. 100, Bdg. 50.1, 66421 Homburg, Germany.
Hittatiya K; Institute of Pathology, University Hospital Bonn, Bdg. 62, Sigmund-Freud Str. 25, 53127 Bonn, Germany.
Schneider G; Clinic for Diagnostic and Interventional Radiology, Saarland University Medical Center, Kirrberger Str. 100, Bdg. 50.1, 66421 Homburg, Germany.
Lammert F; Department of Internal Medicine II, Saarland University, Saarland University Medical Center, Bdg. 77, Kirrberger Str. 100, 66421 Homburg, Germany.
Buecker A; Clinic for Diagnostic and Interventional Radiology, Saarland University Medical Center, Kirrberger Str. 100, Bdg. 50.1, 66421 Homburg, Germany.
Fries P; Clinic for Diagnostic and Interventional Radiology, Saarland University Medical Center, Kirrberger Str. 100, Bdg. 50.1, 66421 Homburg, Germany.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 8720367. Date of Electronic Publication: 2017 Jan 18.
Typ publikacji:: Journal Article
MeSH Terms:: Carbon Tetrachloride Poisoning/*diagnostic imaging
Liver/*diagnostic imaging
Liver Cirrhosis/*diagnostic imaging
Magnetic Resonance Imaging/*methods
ATP Binding Cassette Transporter, Subfamily B/genetics ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; Animals ; Carbon Tetrachloride Poisoning/genetics ; Carbon Tetrachloride Poisoning/metabolism ; Disease Models, Animal ; Humans ; Liver/metabolism ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/genetics ; Liver Cirrhosis/metabolism ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; ATP-Binding Cassette Sub-Family B Member 4

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Skocz do pozycji: 19.

Tytuł:: In vivo studies on the ameliorative effect of coconut water against carbon tetrachloride induced toxicity in rats.
Autorzy:: Elekwa I; Department of Biochemistry, Abia State University, Uturu, Nigeria.
Ude VC; Department of Applied Biochemistry, Enugu State University of Science and Technology, Enugu, Nigeria.
Emmanuel O; Department of Biochemistry, Abia State University, Uturu, Nigeria.
Amachaghi VO; Department of Biochemistry, Abia State University, Uturu, Nigeria.
Ugbogu EA; Department of Biochemistry, Abia State University, Uturu, Nigeria.; Pokaż więcej
Źródło:: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2021 Sep; Vol. 26 (6), pp. 570-577. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji:: Journal Article
MeSH Terms:: Cocos*
Carbon Tetrachloride/*toxicity
Carbon Tetrachloride Poisoning/*prevention & control
Fluid Therapy/*methods
Animals ; Antioxidants/metabolism ; Female ; Lipids/blood ; Male ; Rats ; Rats, Wistar

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Skocz do pozycji: 20.

Tytuł:: Influences of keratinocyte growth factor - mesenchymal stem cells on chronic liver injury in rats.
Autorzy:: Zhang Z; a Anhui Huien Biotech Co., Ltd. , Anhui , China.; b Institute of Advanced Technology, University of Science and Technology of China , Anhui , China.
Pu Y; c Cancer Epigenetics Program, Anhui Cancer Hospital , Anhui , China.
Pan Q; b Institute of Advanced Technology, University of Science and Technology of China , Anhui , China.
Xu X; b Institute of Advanced Technology, University of Science and Technology of China , Anhui , China.
Yan X; b Institute of Advanced Technology, University of Science and Technology of China , Anhui , China.; Pokaż więcej
Źródło:: Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2016 Dec; Vol. 44 (8), pp. 1810-1817. Date of Electronic Publication: 2015 Nov 02.
Typ publikacji:: Journal Article
MeSH Terms:: Adenoviridae*
Carbon Tetrachloride Poisoning*/metabolism
Carbon Tetrachloride Poisoning*/therapy
Fibroblast Growth Factor 7*/biosynthesis
Fibroblast Growth Factor 7*/genetics
Mesenchymal Stem Cell Transplantation*
Transduction, Genetic*
Mesenchymal Stem Cells/*metabolism
Animals ; Chronic Disease ; Humans ; Male ; Rats ; Rats, Wistar

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