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Wyszukujesz frazę ""Carbonic Anhydrases"" wg kryterium: Temat


Tytuł :
Enhanced CO 2 fixation and lipid production of Chlorella vulgaris through the carbonic anhydrase complex.
Autorzy :
You SK; Department of Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Ko YJ; Department of Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Shin SK; Department of Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Hwang DH; Department of Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Kang DH; Department of Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Park HM; Department of Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Han SO; Department of Biotechnology, Korea University, Seoul 02841, Republic of Korea. Electronic address: .
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Źródło :
Bioresource technology [Bioresour Technol] 2020 Dec; Vol. 318, pp. 124072. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Carbonic Anhydrases*
Chlorella vulgaris*
Biofuels ; Carbon Dioxide ; Lipids
Czasopismo naukowe
Tytuł :
Elucidating the role of metal ions in carbonic anhydrase catalysis.
Autorzy :
Kim JK; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Lee C; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Lim SW; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Adhikari A; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Andring JT; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
McKenna R; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Ghim CM; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Kim CU; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea. .
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Źródło :
Nature communications [Nat Commun] 2020 Sep 11; Vol. 11 (1), pp. 4557. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carbonic Anhydrases/*chemistry
Ions/*chemistry
Metalloproteins/*chemistry
Metals/*chemistry
Binding Sites ; Carbonic Anhydrase II/chemistry ; Carbonic Anhydrase II/metabolism ; Carbonic Anhydrases/metabolism ; Catalysis ; Catalytic Domain ; Cobalt/chemistry ; Copper/chemistry ; Crystallography, X-Ray ; Humans ; Ions/metabolism ; Kinetics ; Metalloproteins/metabolism ; Metals/metabolism ; Models, Molecular ; Nickel/chemistry ; Protein Conformation ; Structure-Activity Relationship ; Substrate Specificity ; Zinc/chemistry
Czasopismo naukowe
Tytuł :
Carbonic anhydrase, obstructive sleep apnea and hypertension: Effects of intervention.
Autorzy :
Hoff E; Center for Sleep and Vigilance Disorders, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Zou D; Center for Sleep and Vigilance Disorders, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Schiza S; Sleep Disorders Center, Department of Respiratory Medicine, Medical School, University of Crete, Heraklion, Greece.
Demir Y; Department of Chemistry, Faculty of Sciences, Atatürk University, Erzurum, Turkey.; Department of Pharmacy Services, Nihat Delibalta Göle Vocational High School, Ardahan University, Ardahan, Turkey.
Grote L; Center for Sleep and Vigilance Disorders, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Sleep Disorders Center, Pulmonary Department, Sahlgrenska University Hospital, Gothenburg, Sweden.
Bouloukaki I; Sleep Disorders Center, Department of Respiratory Medicine, Medical School, University of Crete, Heraklion, Greece.
Beydemir Ş; Department of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.
Eskandari D; Center for Sleep and Vigilance Disorders, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Stenlöf K; Center for Sleep and Vigilance Disorders, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Hedner J; Center for Sleep and Vigilance Disorders, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Sleep Disorders Center, Pulmonary Department, Sahlgrenska University Hospital, Gothenburg, Sweden.
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Źródło :
Journal of sleep research [J Sleep Res] 2020 Apr; Vol. 29 (2), pp. e12956. Date of Electronic Publication: 2019 Dec 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carbonic Anhydrases/*adverse effects
Continuous Positive Airway Pressure/*methods
Hypertension/*etiology
Polysomnography/*methods
Sleep Apnea, Obstructive/*physiopathology
Carbonic Anhydrases/blood ; Cohort Studies ; Cross-Over Studies ; Female ; Humans ; Male ; Middle Aged ; Sleep Apnea, Obstructive/pathology ; Sleep Apnea, Obstructive/therapy
Czasopismo naukowe
Tytuł :
Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action.
Autorzy :
Fares M; School of Chemistry & Molecular Bioscience, Molecular Horizons, and Illawarra Health & Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.; School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.
Bua S; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Lanzi C; Department of NEUROFARBA, Section of Pharmacology and Toxicology, University of Florence, Viale Gaetano Pieraccini 6, 50100 Florence, Italy.
Lucarini L; Department of NEUROFARBA, Section of Pharmacology and Toxicology, University of Florence, Viale Gaetano Pieraccini 6, 50100 Florence, Italy.
Masini E; Department of NEUROFARBA, Section of Pharmacology and Toxicology, University of Florence, Viale Gaetano Pieraccini 6, 50100 Florence, Italy.
Peat TS; Biomedical Manufacturing Program, CSIRO, 343 Royal Parade, Parkville, VIC 3052, Australia.
Abdel-Aziz HA; Department of Applied Organic Chemistry, National Research Center, Dokki, Giza 12622, Egypt.
Nocentini A; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Keller PA; School of Chemistry & Molecular Bioscience, Molecular Horizons, and Illawarra Health & Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia.
Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Mar 26; Vol. 63 (6), pp. 3317-3326. Date of Electronic Publication: 2020 Feb 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carbonic Anhydrase Inhibitors/*therapeutic use
Carbonic Anhydrases/*metabolism
Glaucoma/*drug therapy
Intraocular Pressure/*drug effects
Sulfonamides/*therapeutic use
Animals ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/metabolism ; Carbonic Anhydrases/chemistry ; Catalytic Domain ; Crystallography, X-Ray ; Drug Design ; Humans ; Male ; Molecular Structure ; Protein Binding ; Rabbits ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/metabolism
Czasopismo naukowe
Tytuł :
Carbonic anhydrases CA1 and CA4 function in atmospheric CO 2 -modulated disease resistance.
Autorzy :
Zhou Y; Plant-Microbe Interactions, Department of Biology, Science4Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, the Netherlands.
Vroegop-Vos IA; Plant-Microbe Interactions, Department of Biology, Science4Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, the Netherlands.
Van Dijken AJH; Plant-Microbe Interactions, Department of Biology, Science4Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, the Netherlands.
Van der Does D; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, NR4 7UH, UK.
Zipfel C; The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, NR4 7UH, UK.; Department of Plant and Microbial Biology, Zürich-Basel Plant Science Center, University of Zürich, Zurich, Switzerland.
Pieterse CMJ; Plant-Microbe Interactions, Department of Biology, Science4Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, the Netherlands.
Van Wees SCM; Plant-Microbe Interactions, Department of Biology, Science4Life, Utrecht University, Padualaan 8, 3584 CH, Utrecht, the Netherlands. .
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Źródło :
Planta [Planta] 2020 Mar 07; Vol. 251 (4), pp. 75. Date of Electronic Publication: 2020 Mar 07.
Typ publikacji :
Journal Article
MeSH Terms :
Plant Diseases*
Arabidopsis Proteins/*metabolism
Carbon Dioxide/*metabolism
Carbonic Anhydrases/*metabolism
Arabidopsis/genetics ; Arabidopsis/microbiology ; Arabidopsis Proteins/genetics ; Carbonic Anhydrases/genetics ; Disease Resistance ; Plant Immunity ; Pseudomonas syringae/metabolism ; Reactive Oxygen Species/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcriptome
Czasopismo naukowe
Tytuł :
Response to Baertling et al.
Autorzy :
Häberle J; Division of Metabolism, University Children's Hospital Zurich, Zurich, Switzerland. .
Rüfenacht V; Division of Metabolism, University Children's Hospital Zurich, Zurich, Switzerland.
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Źródło :
Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2020 Mar; Vol. 22 (3), pp. 656. Date of Electronic Publication: 2019 Oct 22.
Typ publikacji :
Letter; Comment
MeSH Terms :
Bicarbonates*
Carbonic Anhydrases*
Opinia redakcyjna
Tytuł :
Fatal metabolic decompensation in carbonic anhydrase VA deficiency despite early treatment and control of hyperammonemia.
Autorzy :
Baertling F; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich-Heine-University, Düsseldorf, Germany.
Wagner M; Institute of Human Genetics, Technical University München, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Neurogenomics, Helmholtz Zentrum München, Neuherberg, Germany.
Brunet T; Institute of Human Genetics, Technical University München, Munich, Germany.
Sabir H; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich-Heine-University, Düsseldorf, Germany.
Wieczorek D; Institute of Human Genetics, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Meitinger T; Institute of Human Genetics, Technical University München, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.
Meissner T; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich-Heine-University, Düsseldorf, Germany.
Distelmaier F; Department of General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich-Heine-University, Düsseldorf, Germany. .
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Źródło :
Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2020 Mar; Vol. 22 (3), pp. 654-655. Date of Electronic Publication: 2019 Oct 22.
Typ publikacji :
Letter; Comment
MeSH Terms :
Carbonic Anhydrases*
Hyperammonemia*
Maple Syrup Urine Disease*
Bicarbonates ; Humans ; Liver
Opinia redakcyjna
Tytuł :
Pesticide application inhibit the microbial carbonic anhydrase-mediated carbon sequestration in a soil microcosm.
Autorzy :
Nathan VK; CSIR-National Institute Oceanography, Regional Centre, Dr. Salim Ali Road, Post Box No. 1913, Kochi, 682 018, India.; School of Chemical and Biotechnology, SASTRA Deemed to be University, Thirumalaisamudram, Thanjavur, Tamil Nadu, 613 401, India.
Jasna V; CSIR-National Institute Oceanography, Regional Centre, Dr. Salim Ali Road, Post Box No. 1913, Kochi, 682 018, India.
Parvathi A; CSIR-National Institute Oceanography, Regional Centre, Dr. Salim Ali Road, Post Box No. 1913, Kochi, 682 018, India. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Feb; Vol. 27 (4), pp. 4468-4477. Date of Electronic Publication: 2019 Dec 12.
Typ publikacji :
Journal Article
MeSH Terms :
Carbonic Anhydrases*/chemistry
Pesticides*/chemistry
Carbon Sequestration ; Molecular Docking Simulation ; Soil
Czasopismo naukowe
Tytuł :
Carbonic anhydrase inhibition and chemoreflex control of breathing: A litmus test for methazolamide as a viable alternative to acetazolamide.
Autorzy :
Leacy JK; Department of Physiology, School of Medicine, College of Medicine & Health, University College Cork, Cork, Ireland.
Day TA; Department of Biology, Mount Royal University, Calgary, Alberta, Canada.
O'Halloran KD; Department of Physiology, School of Medicine, College of Medicine & Health, University College Cork, Cork, Ireland.
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Źródło :
Experimental physiology [Exp Physiol] 2020 Feb; Vol. 105 (2), pp. 230-231. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Carbonic Anhydrases*
Methazolamide*
Acetazolamide ; Carbon Dioxide ; Humans ; Respiration
Czasopismo naukowe
Tytuł :
Stabilized and Immobilized Carbonic Anhydrase on Electrospun Nanofibers for Enzymatic CO 2 Conversion and Utilization in Expedited Microalgal Growth.
Autorzy :
Jun SH; Department of Chemical and Biological Engineering , Korea University , Seoul 02841 , Republic of Korea.
Yang J; Department of Chemical and Biological Engineering , Korea University , Seoul 02841 , Republic of Korea.
Jeon H; Department of Genetic Resources Research , National Marine Biodiversity Institute of Korea , Seocheon 33662 , Republic of Korea.
Kim HS; Department of Chemical and Biological Engineering , Korea University , Seoul 02841 , Republic of Korea.
Pack SP; Department of Biotechnology and Bioinformatics , Korea University , Sejong 30019 , Republic of Korea.
Jin E; Department of Life Science, Research Institute for Natural Sciences , Hanyang University , Seoul 04763 , Republic of Korea.
Kim J; Department of Chemical and Biological Engineering , Korea University , Seoul 02841 , Republic of Korea.
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Źródło :
Environmental science & technology [Environ Sci Technol] 2020 Jan 21; Vol. 54 (2), pp. 1223-1231. Date of Electronic Publication: 2020 Jan 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carbonic Anhydrases*
Microalgae*
Nanofibers*
Animals ; Bicarbonates ; Carbon Dioxide ; Cattle ; Enzymes, Immobilized
Czasopismo naukowe
Tytuł :
Carbonic anhydrase modification for carbon management.
Autorzy :
Giri A; Department of Environmental Sciences, Central University of Himachal Pradesh, Kangra, India.
Pant D; School of Chemical Sciences, Central University of Haryana, Mahendragarh, Haryana, 123029, India. .
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Źródło :
Environmental science and pollution research international [Environ Sci Pollut Res Int] 2020 Jan; Vol. 27 (2), pp. 1294-1318. Date of Electronic Publication: 2019 Dec 03.
Typ publikacji :
Journal Article
MeSH Terms :
Carbonic Anhydrases*
Carbon Dioxide/*chemistry
Czasopismo naukowe
Tytuł :
Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach.
Autorzy :
De Simone G; Istituto di Biostrutture e Bioimmagini-CNR , Naples , Italy.
Di Fiore A; Istituto di Biostrutture e Bioimmagini-CNR , Naples , Italy.
Truppo E; Istituto di Biostrutture e Bioimmagini-CNR , Naples , Italy.
Langella E; Istituto di Biostrutture e Bioimmagini-CNR , Naples , Italy.
Vullo D; Neurofarba Department, Università degli Studi di Firenze, Sezione di Scienze Farmaceutiche e Nutraceutiche , Sesto Fiorentino , Florence , Italy.
Supuran CT; Neurofarba Department, Università degli Studi di Firenze, Sezione di Scienze Farmaceutiche e Nutraceutiche , Sesto Fiorentino , Florence , Italy.
Monti SM; Istituto di Biostrutture e Bioimmagini-CNR , Naples , Italy.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2019 Dec; Vol. 34 (1), pp. 1506-1510.
Typ publikacji :
Journal Article
MeSH Terms :
Biocatalysis*
Mutagenesis, Site-Directed*
Carbonic Anhydrases/*genetics
Carbonic Anhydrases/*metabolism
Carbonic Anhydrases/chemistry ; Dose-Response Relationship, Drug ; Humans ; Models, Molecular ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation.
Autorzy :
Abdelrahman MA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Egypt.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Nocentini A; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Firenze, Italy.
Ibrahim HS; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Egypt.
Almahli H; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, UK.
Abdel-Aziz HA; Department of Applied Organic Chemistry, National Research Center, Dokki, Egypt.
Abou-Seri SM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Supuran CT; Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Firenze, Italy.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 298-305.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Benzofurans/*pharmacology
Carbonic Anhydrase IX/*antagonists & inhibitors
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Sulfonamides/*pharmacology
Antigens, Neoplasm/metabolism ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Benzofurans/chemistry ; Carbonic Anhydrase IX/metabolism ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship ; Sulfonamides/chemical synthesis ; Sulfonamides/chemistry
Czasopismo naukowe
Tytuł :
Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM.
Autorzy :
Soufari H; Institut Européen de Chimie et Biologie, U1212 Inserm, Université de Bordeaux, 2 rue R. Escarpit, F-33600, Pessac, France.
Parrot C; Institut Européen de Chimie et Biologie, U1212 Inserm, Université de Bordeaux, 2 rue R. Escarpit, F-33600, Pessac, France.
Kuhn L; Plateforme protéomique Strasbourg Esplanade FRC1589 du CNRS, Université de Strasbourg, Strasbourg, France.
Waltz F; Institut Européen de Chimie et Biologie, U1212 Inserm, Université de Bordeaux, 2 rue R. Escarpit, F-33600, Pessac, France. .
Hashem Y; Institut Européen de Chimie et Biologie, U1212 Inserm, Université de Bordeaux, 2 rue R. Escarpit, F-33600, Pessac, France. .
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Źródło :
Nature communications [Nat Commun] 2020 Oct 15; Vol. 11 (1), pp. 5195. Date of Electronic Publication: 2020 Oct 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cryoelectron Microscopy/*methods
Electron Transport Complex I/*chemistry
Electron Transport Complex I/*metabolism
Mitochondria/*metabolism
Arabidopsis/metabolism ; Brassica ; Carbonic Anhydrases/chemistry ; Carbonic Anhydrases/metabolism ; Cardiolipins/metabolism ; Gene Expression Regulation, Plant ; Mitochondrial Membranes/metabolism ; Plant Proteins/chemistry ; Plant Proteins/metabolism ; Protein Conformation ; Proteomics
Czasopismo naukowe
Tytuł :
Characterization and High-Level Periplasmic Expression of Thermostable α-Carbonic Anhydrase from Thermosulfurimonas Dismutans in Escherichia Coli for CO 2 Capture and Utilization.
Autorzy :
Jo BH; Division of Life Science and Research Institute of Life Science, Gyeongsang National University, Jinju 52828, Korea.
Hwang IS; Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2019 Dec 22; Vol. 21 (1). Date of Electronic Publication: 2019 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Bacteria/*enzymology
Bacterial Proteins/*metabolism
Carbon Dioxide/*metabolism
Carbonic Anhydrases/*metabolism
Escherichia coli/*metabolism
Periplasm/*enzymology
Amino Acid Sequence ; Bacteria/genetics ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Carbonic Anhydrases/chemistry ; Carbonic Anhydrases/genetics ; Enzyme Stability ; Escherichia coli/genetics ; Gene Expression Regulation, Enzymologic ; Hydrothermal Vents ; Industrial Microbiology/methods ; Periplasm/genetics ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Sequence Homology, Amino Acid ; Solubility ; Temperature
SCR Organism :
Thermosulfurimonas dismutans
Czasopismo naukowe
Tytuł :
Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery.
Autorzy :
Nocentini A; Department of Neuroscience, Psychology, Drug Research and Child's Health (NEUROFARBA), Section of Pharmaceutical and Nutraceutical Sciences, University of Florence , Florence , Italy.
Supuran CT; Department of Neuroscience, Psychology, Drug Research and Child's Health (NEUROFARBA), Section of Pharmaceutical and Nutraceutical Sciences, University of Florence , Florence , Italy.
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Źródło :
Expert opinion on drug discovery [Expert Opin Drug Discov] 2019 Nov; Vol. 14 (11), pp. 1175-1197. Date of Electronic Publication: 2019 Aug 22.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*drug effects
Drug Discovery/*methods
Animals ; Carbonic Anhydrase Inhibitors/chemistry ; Carbonic Anhydrases/chemistry ; Carbonic Anhydrases/metabolism ; Catalytic Domain ; Drug Design ; Humans ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation.
Autorzy :
Fois B; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Distinto S; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Meleddu R; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Deplano S; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Maccioni E; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Floris C; Department of Chemical and Geological Sciences, University of Cagliari, Cagliari, Italy.
Rosa A; Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Cagliari, Italy.
Nieddu M; Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, Cagliari, Italy.
Caboni P; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Sissi C; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Angeli A; NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Firenze, Italy.
Supuran CT; NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Firenze, Italy.
Cottiglia F; Department of Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 539-548.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Apiaceae/*chemistry
Carbonic Anhydrase IX/*antagonists & inhibitors
Carbonic Anhydrase Inhibitors/*isolation & purification
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Coumarins/*isolation & purification
Coumarins/*pharmacology
Antigens, Neoplasm/metabolism ; Carbonic Anhydrase IX/metabolism ; Carbonic Anhydrase Inhibitors/chemistry ; Coumarins/chemistry ; Dose-Response Relationship, Drug ; Humans ; Molecular Structure ; Seeds/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Bioorganometallic derivatives of 4-hydrazino-benzenesulphonamide as carbonic anhydrase inhibitors: synthesis, characterisation and biological evaluation.
Autorzy :
Brichet J; Laboratorio de Química Inorgánica y Organometálica, Departamento de Química Analítica e Inorgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción, Chile.
Arancibia R; Laboratorio de Química Inorgánica y Organometálica, Departamento de Química Analítica e Inorgánica, Facultad de Ciencias Químicas, Universidad de Concepción, Concepción, Chile.
Berrino E; Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche, Università degli Studi di Firenze, Firenze, Italy.
Supuran CT; Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche, Università degli Studi di Firenze, Firenze, Italy.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 622-628.
Typ publikacji :
Journal Article
MeSH Terms :
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Hydrazines/*pharmacology
Organometallic Compounds/*pharmacology
Sulfonamides/*pharmacology
Carbon Dioxide/antagonists & inhibitors ; Carbon Dioxide/chemistry ; Carbon Dioxide/metabolism ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Humans ; Hydrazines/chemistry ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Molecular Structure ; Organometallic Compounds/chemical synthesis ; Organometallic Compounds/chemistry ; Structure-Activity Relationship ; Sulfonamides/chemistry
Czasopismo naukowe
Tytuł :
A class of carbonic anhydrase IX/XII - selective carboxylate inhibitors.
Autorzy :
Alhameed RA; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Berrino E; Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Florence, Italy.
Almarhoon Z; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
El-Faham A; Department of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.; Chemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt.
Supuran CT; Dipartimento Neurofarba, Sezione di Scienze Farmaceutiche e Nutraceutiche, Università degli Studi di Firenze, Florence, Italy.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 549-554.
Typ publikacji :
Journal Article
MeSH Terms :
Acetates/*pharmacology
Carbonic Anhydrase IX/*antagonists & inhibitors
Carbonic Anhydrase Inhibitors/*classification
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Thiazoles/*pharmacology
Acetates/chemical synthesis ; Acetates/chemistry ; Antigens, Neoplasm/metabolism ; Carbonic Anhydrase IX/metabolism ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Dose-Response Relationship, Drug ; Humans ; Molecular Structure ; Structure-Activity Relationship ; Thiazoles/chemical synthesis ; Thiazoles/chemistry
Czasopismo naukowe
Tytuł :
A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors.
Autorzy :
Llanos MA; Laboratory of Bioactive Research and Development (LIDeB), Medicinal Chemistry, Department of Biological Sciences, Faculty of Exact Sciences, National University of La Plata , Buenos Aires , Argentina.
Sbaraglini ML; Laboratory of Bioactive Research and Development (LIDeB), Medicinal Chemistry, Department of Biological Sciences, Faculty of Exact Sciences, National University of La Plata , Buenos Aires , Argentina.
Villalba ML; Laboratory of Bioactive Research and Development (LIDeB), Medicinal Chemistry, Department of Biological Sciences, Faculty of Exact Sciences, National University of La Plata , Buenos Aires , Argentina.
Ruiz MD; Instituto de Ciencias y Tecnología Dr. Cesar Milstein (ICT Milstein), Argentinean National Council of Scientific and Technical Research (CONICET) , Buenos Aires , Argentina.
Carrillo C; Instituto de Ciencias y Tecnología Dr. Cesar Milstein (ICT Milstein), Argentinean National Council of Scientific and Technical Research (CONICET) , Buenos Aires , Argentina.
Alba Soto C; Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Instituto de Investigaciones en Microbiología y Parasitología Médica (IMPaM), UBA-CONICET , Buenos Aires , Argentina.
Talevi A; Laboratory of Bioactive Research and Development (LIDeB), Medicinal Chemistry, Department of Biological Sciences, Faculty of Exact Sciences, National University of La Plata , Buenos Aires , Argentina.
Angeli A; Neurofarba Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Universita degli Studi di Firenze , Sesto Fiorentino , Florence , Italy.
Parkkila S; Faculty of Medicine and Health Technology, University of Tampere , Tampere , Finland.
Supuran CT; Neurofarba Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Universita degli Studi di Firenze , Sesto Fiorentino , Florence , Italy.
Gavernet L; Laboratory of Bioactive Research and Development (LIDeB), Medicinal Chemistry, Department of Biological Sciences, Faculty of Exact Sciences, National University of La Plata , Buenos Aires , Argentina.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 21-30.
Typ publikacji :
Journal Article
MeSH Terms :
Carbonic Anhydrase Inhibitors/*pharmacology
Carbonic Anhydrases/*metabolism
Chagas Disease/*drug therapy
Cyclamates/*pharmacology
Trypanocidal Agents/*pharmacology
Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Chagas Disease/metabolism ; Cyclamates/chemical synthesis ; Cyclamates/chemistry ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Humans ; Models, Molecular ; Molecular Structure ; Parasitic Sensitivity Tests ; Structure-Activity Relationship ; Trypanocidal Agents/chemical synthesis ; Trypanocidal Agents/chemistry ; Trypanosoma cruzi/drug effects ; Trypanosoma cruzi/enzymology
Czasopismo naukowe

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