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Wyszukujesz frazę ""Carcinogenicity Tests"" wg kryterium: Temat


Tytuł :
The 2-year rodent bioassay in drug and chemical carcinogenesis testing: Sensitivity, according to the framework of carcinogenic action.
Autorzy :
Suarez-Torres JD; Department of Pharmacy, Universidad Nacional de Colombia, Bogotá, Colombia.; Department of Toxicology, Universidad Nacional de Colombia, Bogotá, Colombia.; Institute of Pharmaceutical Research, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.
Jimenez-Orozco FA; Department of Pharmacology, Faculty of Medicine, Universidad Nacional Autónoma de México, Ciudad de Mexico, Mexico.
Ciangherotti CE; Institute of Pharmaceutical Research, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.; Laboratory of Neuropeptides, School of Pharmacy, Universidad Central de Venezuela, Caracas, Venezuela.
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Źródło :
Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Jul; Vol. 30 (6), pp. 462-475. Date of Electronic Publication: 2020 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Biological Assay*
Carcinogenicity Tests*
Carcinogens/*toxicity
Cell Transformation, Neoplastic/*chemically induced
Neoplasms/*chemically induced
Animals ; Databases, Factual ; Female ; Humans ; Male ; Mice ; Rats ; Risk Assessment ; Time Factors
Czasopismo naukowe
Tytuł :
Thresholds for carcinogens.
Autorzy :
Calabrese EJ; Department of Environmental Health Sciences, Morrill I, N344, University of Massachusetts, Amherst, MA, 01003, USA. Electronic address: .
Priest ND; Chemistry Department, Laval University, Quebec City, QC, Canada. Electronic address: .
Kozumbo WJ; 7 West Melrose Avenue, Baltimore, MD 21210, USA. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 May 25; Vol. 341, pp. 109464. Date of Electronic Publication: 2021 Apr 03.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinogenicity Tests/*methods
Carcinogens/*administration & dosage
Carcinogens/*toxicity
Neoplasms/*chemically induced
Animals ; Dose-Response Relationship, Drug ; Hormesis ; Humans ; Incidence ; Neoplasms/epidemiology ; Risk Assessment/methods ; Toxicity Tests, Chronic/methods
Czasopismo naukowe
Tytuł :
Lack of potential carcinogenicity for aspartame - Systematic evaluation and integration of mechanistic data into the totality of the evidence.
Autorzy :
Wikoff DS; ToxStrategies, USA. Electronic address: .
Chappell GA; ToxStrategies, USA.
Fitch S; ToxStrategies, USA.
Doepker CL; ToxStrategies, USA.
Borghoff SJ; ToxStrategies, USA.
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Źródło :
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2020 Jan; Vol. 135, pp. 110866. Date of Electronic Publication: 2019 Oct 12.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Carcinogenicity Tests*
Aspartame/*toxicity
Sweetening Agents/*toxicity
Animals ; Humans
Czasopismo naukowe
Tytuł :
Analysis of heavy metal content in edible honeysuckle ( Lonicera japonica Thunb.) from China and health risk assessment.
Autorzy :
Fan L; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Chen L; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Cui W; College of Food Science and Engineering, Shandong Agricultural University, Taian, Shandong, China.
Dong Y; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Yuan X; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Wang L; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Liang J; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
Zhao S; Institute of Quality Standard & Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, China.
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Źródło :
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes [J Environ Sci Health B] 2020; Vol. 55 (10), pp. 921-928. Date of Electronic Publication: 2020 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenicity Tests*
Environmental Monitoring*
Lonicera/*chemistry
Metals, Heavy/*analysis
Soil Pollutants/*analysis
China ; Humans ; Risk Assessment
Czasopismo naukowe
Tytuł :
Incidental Ultrastructural Findings in the Sural Nerve and Dorsal Root Ganglion of Aged Control Sprague Dawley Rats in a Nonclinical Carcinogenicity Study.
Autorzy :
Meier WA; Covance Laboratories, Madison, WI, USA.
Linn MJ; Covance Laboratories, Madison, WI, USA.
Davis WP; Alnylam Pharmaceuticals, Inc, Cambridge, MA, USA.
Sutherland JE; Alnylam Pharmaceuticals, Inc, Cambridge, MA, USA.
Sharma AK; Covance Laboratories, Madison, WI, USA.
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Źródło :
Toxicologic pathology [Toxicol Pathol] 2020 Jan; Vol. 48 (1), pp. 132-143. Date of Electronic Publication: 2019 Nov 20.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenicity Tests*
Ganglia, Spinal/*ultrastructure
Sural Nerve/*ultrastructure
Animals ; Male ; Myelin Sheath ; Peripheral Nervous System Diseases ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Tetrahydrofuran-induced tumors in rodents are not relevant to humans: Quantitative weight of evidence analysis of mode of action information does not support classification of tetrahydrofuran as a possible human carcinogen.
Autorzy :
Dekant W; Department of Pharmacology and Toxicology, University of Würzburg, 97078, Würzburg, Germany. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2019 Dec; Vol. 109, pp. 104499. Date of Electronic Publication: 2019 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenicity Tests/*methods
Furans/*toxicity
Kidney Neoplasms/*chemically induced
Liver Neoplasms/*chemically induced
Neoplasms, Experimental/*chemically induced
Solvents/*toxicity
Animals ; Body Weight ; Carcinogenicity Tests/standards ; Cell Proliferation ; Female ; Humans ; Incidence ; Inhalation Exposure/adverse effects ; Kidney Neoplasms/epidemiology ; Kidney Neoplasms/pathology ; Liver Neoplasms/epidemiology ; Liver Neoplasms/pathology ; Male ; Mice ; Neoplasms, Experimental/epidemiology ; Neoplasms, Experimental/pathology ; Rats ; Receptors, Cytoplasmic and Nuclear/metabolism ; Research Design/standards ; Sex Factors ; Species Specificity ; Toxicology/methods ; Toxicology/standards
Czasopismo naukowe
Tytuł :
The Single-Cell Gel Electrophoresis Genotoxin Sensitivity Assay.
Autorzy :
Ferk F; Department of Internal Medicine I, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.
Mišík M; Department of Internal Medicine I, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.
Al-Serori H; Department of Internal Medicine I, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.
Nersesyan A; Department of Internal Medicine I, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.
Wultsch G; Department of Internal Medicine I, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria.
Knasmueller S; Department of Internal Medicine I, Institute of Cancer Research, Medical University of Vienna, Vienna, Austria. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2240, pp. 1-12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinogenicity Tests/*methods
Carcinogens/*toxicity
Comet Assay/*methods
Mutagens/*toxicity
Single-Cell Analysis/*methods
Cell Survival ; Cells, Cultured ; DNA Damage ; Humans ; Lymphocytes/drug effects
Czasopismo naukowe
Tytuł :
Carcinogenicity of acrolein, crotonaldehyde, and arecoline.
Corporate Authors :
IARC Monographs Vol 128 group
Źródło :
The Lancet. Oncology [Lancet Oncol] 2021 Jan; Vol. 22 (1), pp. 19-20. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Wiadomości
MeSH Terms :
Acrolein/*toxicity
Aldehydes/*toxicity
Arecoline/*toxicity
Carcinogens, Environmental/*toxicity
Neoplasms/*chemically induced
Animals ; Carcinogenicity Tests ; Consensus Development Conferences as Topic ; Environmental Exposure/adverse effects ; Humans ; Internet ; Risk Assessment ; Telecommunications
Periodyk
Tytuł :
Quantitative analysis of mutagenicity and carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in F344 gpt delta transgenic rats.
Autorzy :
Gi M; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan.
Fujioka M; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan.
Totsuka Y; Division of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.
Matsumoto M; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Kanagawa, Japan.
Masumura K; Division of Genetics and Mutagenesis, National Institute of Health Sciences, Kawasaki-ku, Kawasaki, Kanagawa, Japan.
Kakehashi A; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan.
Yamaguchi T; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan.
Fukushima S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Kanagawa, Japan.; Association for Promotion of Research on Risk Assessment, Nakagawa-ku, Nagoya, Japan.
Wanibuchi H; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan.
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Źródło :
Mutagenesis [Mutagenesis] 2019 Sep 20; Vol. 34 (3), pp. 279-287.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinogenicity Tests*/methods
Mutagenicity Tests*/methods
Carcinogens/*toxicity
Mutagens/*toxicity
Quinolines/*toxicity
Animals ; Dose-Response Relationship, Drug ; Humans ; Immunohistochemistry ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Male ; Mutagenesis/drug effects ; Quinolines/chemistry ; Rats ; Rats, Inbred F344 ; Rats, Transgenic
Czasopismo naukowe
Tytuł :
Epigenetic silencing of ALX4 regulates microcystin-LR induced hepatocellular carcinoma through the P53 pathway.
Autorzy :
Zhao J; Institute of Toxicology, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China; College of Public Health and Management, Ningxia Medical University, Yinchuan 750004, PR China.
Chen HQ; Institute of Toxicology, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China.
Yang HF; College of Public Health and Management, Ningxia Medical University, Yinchuan 750004, PR China.
Li Y; Institute of Toxicology, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China; The Calmette International Hospital, Kunming 650224, PR China.
Chen DJ; Institute of Toxicology, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China; College of Public Health and Management, Ningxia Medical University, Yinchuan 750004, PR China.
Huang YJ; Department of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China.
He LX; Department of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China.
Zheng CF; Department of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China.
Wang LQ; Department of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China.
Wang J; Department of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China.
Zhang N; College of Public Health and Management, Ningxia Medical University, Yinchuan 750004, PR China.
Cao J; Institute of Toxicology, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China.
Liu JY; Institute of Toxicology, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China.
Shu WQ; Department of Environmental Hygiene, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China. Electronic address: .
Liu WB; Institute of Toxicology, College of Preventive Medicine, Third Military Medical University (Army Medical University), Chongqing 400038, PR China. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2019 Sep 15; Vol. 683, pp. 317-330. Date of Electronic Publication: 2019 May 15.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenicity Tests*
Epigenesis, Genetic*
Carcinoma, Hepatocellular/*chemically induced
DNA-Binding Proteins/*genetics
Liver Neoplasms/*chemically induced
Microcystins/*toxicity
Tumor Suppressor Protein p53/*genetics
Animals ; Carcinogenesis ; Carcinoma, Hepatocellular/genetics ; DNA-Binding Proteins/metabolism ; Liver Neoplasms/genetics ; Marine Toxins ; Rats ; Tumor Suppressor Protein p53/metabolism
Czasopismo naukowe
Tytuł :
Proportional hazards regression of survival-sacrifice data with cause-of-death information in animal carcinogenicity studies.
Autorzy :
Mao L; Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin.
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Źródło :
Statistics in medicine [Stat Med] 2019 Aug 30; Vol. 38 (19), pp. 3628-3641. Date of Electronic Publication: 2019 May 09.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenicity Tests*
Cause of Death*
Proportional Hazards Models*
Regression Analysis*
Animals ; Computer Simulation ; Likelihood Functions ; Mice ; Rats
Czasopismo naukowe
Tytuł :
The selective determination of potentially carcinogenic polycyclic aromatic compounds in lubricant base oils by the DMSO extraction method IP346 and its correlation to mouse skin painting carcinogenicity assays.
Autorzy :
Carrillo JC; Shell Health, Shell International B.V, the Netherlands. Electronic address: .
van der Wiel A; Koninklijke Shell Laboratorium Amsterdam (now Shell Technology Centre Amsterdam), the Netherlands.
Danneels D; European Wax Federation aisbl, Belgium.
Kral O; Shell Deutschland Oil GmbH, Germany.
Boogaard PJ; Shell Health, Shell International B.V, the Netherlands.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2019 Aug; Vol. 106, pp. 316-333. Date of Electronic Publication: 2019 May 16.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenicity Tests*
Carcinogens/*pharmacology
Dimethyl Sulfoxide/*chemistry
Lubricants/*chemistry
Mineral Oil/*chemistry
Polycyclic Aromatic Hydrocarbons/*pharmacology
Skin/*drug effects
Skin Neoplasms/*chemically induced
Animals ; Carcinogens/chemistry ; Europe ; Mice ; Mineral Oil/isolation & purification ; Molecular Structure ; Polycyclic Aromatic Hydrocarbons/chemistry ; Skin/pathology ; Skin Neoplasms/pathology
Czasopismo naukowe
Tytuł :
The impact on classifications for carcinogenicity, mutagenicity, reproductive and specific target organ toxicity after repeated exposure in the first ten years of the REACH regulation.
Autorzy :
Karamertzanis PG; Computational Assessment and Dissemination Unit, Registration Directorate, European Chemicals Agency (ECHA), Helsinki, 00120, Finland. Electronic address: .
Atlason P; Classification and Prioritisation Unit, Risk Management Directorate, European Chemicals Agency (ECHA), Helsinki, 00120, Finland.
Nathanail AV; Classification and Prioritisation Unit, Risk Management Directorate, European Chemicals Agency (ECHA), Helsinki, 00120, Finland.
Provoost J; Computational Assessment and Dissemination Unit, Registration Directorate, European Chemicals Agency (ECHA), Helsinki, 00120, Finland.
Karhu E; Classification and Prioritisation Unit, Risk Management Directorate, European Chemicals Agency (ECHA), Helsinki, 00120, Finland.
Rasenberg M; Computational Assessment and Dissemination Unit, Registration Directorate, European Chemicals Agency (ECHA), Helsinki, 00120, Finland.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2019 Aug; Vol. 106, pp. 303-315. Date of Electronic Publication: 2019 May 11.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenicity Tests*
Mutagenicity Tests*
Animal Testing Alternatives/*legislation & jurisprudence
Organic Chemicals/*adverse effects
Animals ; European Union ; Humans ; Organic Chemicals/administration & dosage
Czasopismo naukowe
Tytuł :
Urinary crystal formation and urothelial effects of pyroxasulfone administered to male rats.
Autorzy :
Kyoya T; Kumiai Chemical Industry Co., Ltd, Shizuoka, Japan and Tokyo.
Arnold LL; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Pennington KL; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Kakiuchi-Kiyota S; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.; Safety Assessment, Genentech Inc, South San Francisco, CA, USA.
Terada M; Kumiai Chemical Industry Co., Ltd, Shizuoka, Japan and Tokyo.
Abe K; Kumiai Chemical Industry Co., Ltd, Shizuoka, Japan and Tokyo.
Cohen SM; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.; Havlik-Wall Professor of Oncology and Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
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Źródło :
Toxicology mechanisms and methods [Toxicol Mech Methods] 2020 Nov; Vol. 30 (9), pp. 656-671. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Proliferation/*drug effects
Herbicides/*toxicity
Isoxazoles/*toxicity
Sulfones/*toxicity
Urinary Bladder Neoplasms/*chemically induced
Urinary Calculi/*chemically induced
Urothelium/*drug effects
Animals ; Carcinogenicity Tests ; Crystallization ; Dose-Response Relationship, Drug ; Hyperplasia ; Male ; Necrosis ; Rats, Sprague-Dawley ; Risk Assessment ; Time Factors ; Urinary Bladder Neoplasms/pathology ; Urinary Calculi/urine ; Urothelium/ultrastructure
Czasopismo naukowe
Tytuł :
Are all nitrosamines concerning? A review of mutagenicity and carcinogenicity data.
Autorzy :
Thresher A; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, West Yorkshire, LS11 5PS, UK. Electronic address: .
Foster R; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, West Yorkshire, LS11 5PS, UK.
Ponting DJ; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, West Yorkshire, LS11 5PS, UK.
Stalford SA; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, West Yorkshire, LS11 5PS, UK.
Tennant RE; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, West Yorkshire, LS11 5PS, UK.
Thomas R; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, West Yorkshire, LS11 5PS, UK.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Oct; Vol. 116, pp. 104749. Date of Electronic Publication: 2020 Aug 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinogens/*toxicity
Mutagens/*toxicity
Nitrosamines/*toxicity
Animals ; Carcinogenicity Tests ; Mutagenicity Tests
Czasopismo naukowe
Tytuł :
Trump Administration stymies US EPA's chemical carcinogenicity and toxicity assessments.
Autorzy :
Furlow B
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Źródło :
The Lancet. Oncology [Lancet Oncol] 2019 May; Vol. 20 (5), pp. 617. Date of Electronic Publication: 2019 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenicity Tests*
Government Regulation*
Policy Making*
Politics*
Toxicity Tests*
United States Environmental Protection Agency/*legislation & jurisprudence
Conflict of Interest ; Humans ; Risk Assessment ; United States
Czasopismo naukowe
Tytuł :
Chemical carcinogenicity revisited 3: Risk assessment of carcinogenic potential based on the current state of knowledge of carcinogenesis in humans.
Autorzy :
Cohen SM; Department of Pathology and Microbiology, Havlik-Wall Professor of Oncology, University of Nebraska Medical Center, Omaha, NE, 68198-3135, USA.
Boobis AR; Centre for Pharmacology & Therapeutics, Toxicology Unit, Department of Medicine, Hammersmith Campus, Imperial College London, London, W12 0NN, UK.
Dellarco VL; Independent Consultant, Silver Spring, MD, 20901, USA.
Doe JE; Parker Doe LLP, Carpenter Court, Maple Road, Bramhall, Stockport, Cheshire, SK7 2DH, UK. Electronic address: .
Fenner-Crisp PA; Independent Consultant, North Garden, VA, 22959, USA.
Moretto A; Dipartimento di Scienze Biochimiche e Cliniche, Università degli Studi di Milano, Milan, Italy.
Pastoor TP; Pastoor Science Communication, LLC, Greensboro, NC, 27455, USA.
Schoeny RS; Rita Schoeny LLC, Washington DC, 20002, USA.
Seed JG; Independent Consultant, Alexandria, VA, 22301, USA.
Wolf DC; Syngenta Crop Protection, LLC, Greensboro, NC, 27419, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2019 Apr; Vol. 103, pp. 100-105. Date of Electronic Publication: 2019 Jan 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinogenicity Tests*
Carcinogenesis/*chemically induced
Carcinogens/*chemistry
Humans ; Risk Assessment
Czasopismo naukowe
Tytuł :
Chemical carcinogenicity revisited 1: A unified theory of carcinogenicity based on contemporary knowledge.
Autorzy :
Wolf DC; Syngenta Crop Protection LLC, Greensboro, NC, 27419, USA.
Cohen SM; Department of Pathology and Microbiology, Havlik-Wall Professor of Oncology, University of Nebraska Medical Center, Omaha, NE, 68198-3135, USA.
Boobis AR; Centre for Pharmacology & Therapeutics, Toxicology Unit, Department of Medicine, Hammersmith Campus, Imperial College London, London, W12 0NN, UK.
Dellarco VL; Independent Consultant, Silver Spring, MD, 20901, USA.
Fenner-Crisp PA; Independent Consultant, North Garden, VA, 22959, USA.
Moretto A; Dipartimento di Scienze Biochimiche e Cliniche (Department of Biomedical and Clinical Sciences), Università degli Studi di Milano, Milan, Italy.
Pastoor TP; Pastoor Science Communication, LLC, Greensboro, NC, 27455, USA.
Schoeny RS; Rita Schoeny LLC, Washington DC, 20002, USA.
Seed JG; Independent Consultant, Alexandria, VA, 22301, USA.
Doe JE; Parker Doe LLP, Carpenter Court, Maple Road, Bramhall, Stockport, Cheshire, SK7 2DH, UK. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2019 Apr; Vol. 103, pp. 86-92. Date of Electronic Publication: 2019 Jan 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinogenicity Tests*
Carcinogens/*chemistry
Carcinogens/*pharmacology
Neoplasms/*chemically induced
Animals ; DNA, Neoplasm/drug effects ; Humans
Czasopismo naukowe
Tytuł :
The Carcinogenome Project: In Vitro Gene Expression Profiling of Chemical Perturbations to Predict Long-Term Carcinogenicity.
Autorzy :
Li A; 1 Computational Biomedicine, Boston University School of Medicine , Boston, Massachusetts, USA.; 2 Bioinformatics Program, Boston University , Boston, Massachusetts, USA.
Lu X; 3 Cancer Program, Broad Institute of MIT and Harvard , Cambridge, Massachusetts, USA.
Natoli T; 3 Cancer Program, Broad Institute of MIT and Harvard , Cambridge, Massachusetts, USA.
Bittker J; 3 Cancer Program, Broad Institute of MIT and Harvard , Cambridge, Massachusetts, USA.
Sipes NS; 4 Toxicoinformatics Group, National Institute of Environmental Health Sciences , Durham, North Carolina, USA.
Subramanian A; 3 Cancer Program, Broad Institute of MIT and Harvard , Cambridge, Massachusetts, USA.
Auerbach S; 4 Toxicoinformatics Group, National Institute of Environmental Health Sciences , Durham, North Carolina, USA.
Sherr DH; 5 Department of Environmental Health, Boston University School of Public Health , Boston, Massachusetts, USA.
Monti S; 1 Computational Biomedicine, Boston University School of Medicine , Boston, Massachusetts, USA.; 2 Bioinformatics Program, Boston University , Boston, Massachusetts, USA.
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Źródło :
Environmental health perspectives [Environ Health Perspect] 2019 Apr; Vol. 127 (4), pp. 47002.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinogenicity Tests/*methods
Carcinogens/*toxicity
Gene Expression Profiling/*methods
Toxicogenetics/*methods
Area Under Curve ; Carcinogenicity Tests/instrumentation ; DNA Damage ; Gene Expression Profiling/instrumentation ; Hep G2 Cells ; Humans ; In Vitro Techniques/instrumentation ; In Vitro Techniques/methods ; ROC Curve
Czasopismo naukowe
Tytuł :
A Comparison of Spontaneous Tumors in Tg.rasH2 Mice in 26-week Carcinogenicity Studies Conducted at a Single Test Facility during 2004 to 2012 and 2013 to 2018.
Autorzy :
Paranjpe MG; 1 MPI Research (a Charles River Company), Mattawan, Michigan, USA.
Belich JL; 2 MilliporeSigma BioReliance® Toxicology Services, Rockville, Maryland, USA.
Mann PC; 3 Experimental Pathology Laboratories Inc., Seattle, Washington, USA.
McKeon ME; 2 MilliporeSigma BioReliance® Toxicology Services, Rockville, Maryland, USA.
Elbekai RH; 4 Otsuka Pharmaceuticals, Rockville, Maryland, USA.
Brown CM; 2 MilliporeSigma BioReliance® Toxicology Services, Rockville, Maryland, USA.
Patrick DJ; 1 MPI Research (a Charles River Company), Mattawan, Michigan, USA.
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Źródło :
Toxicologic pathology [Toxicol Pathol] 2019 Jan; Vol. 47 (1), pp. 18-25. Date of Electronic Publication: 2018 Nov 08.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinogenicity Tests*/methods
Carcinogenicity Tests*/standards
Genes, ras*
Mice, Transgenic*
Neoplasms, Experimental/*epidemiology
Rodent Diseases/*epidemiology
Animals ; Female ; Incidence ; Male ; Mice ; Neoplasms, Experimental/genetics ; Neoplasms, Experimental/pathology ; Random Allocation ; Rodent Diseases/genetics ; Rodent Diseases/pathology ; Sex Factors
Czasopismo naukowe

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