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Wyszukujesz frazę ""Carcinoma, Non-Small-Cell Lung"" wg kryterium: Temat


Tytuł:
Exosomal epidermal growth factor receptor is involved in HPV-16 E7-induced epithelial-mesenchymal transition of non-small cell lung cancer cells: A driver of signaling in vivo?
Autorzy:
Zhou Z; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.
Wu X; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.; Center for Laboratory Medicine, Department of Blood Transfusion, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Zhan R; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.; Center for Laboratory Medicine, Department of Blood Transfusion, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Li X; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Dongguan Key Laboratory of Medical Bioactive Molecular Developmental and Translational Research, Guangdong Medical University, Dongguan, China.
Cheng D; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.
Chen L; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.
Wang T; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.
Yu H; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.
Zhang G; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.
Tang X; Institute of Biochemistry and Molecular Biology, Collaborative Innovation Center for antitumor active substance research and development, Guangdong Medical University, Zhanjiang, China.; Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Dongguan Key Laboratory of Medical Bioactive Molecular Developmental and Translational Research, Guangdong Medical University, Dongguan, China.
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Źródło:
Cancer biology & therapy [Cancer Biol Ther] 2022 Dec 31; Vol. 23 (1), pp. 1-13.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Exosomes*/metabolism
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
MicroRNAs*/genetics
Papillomavirus Infections*/complications
Cell Line, Tumor ; Epithelial-Mesenchymal Transition/genetics ; ErbB Receptors/genetics ; Human papillomavirus 16 ; Humans ; Papillomavirus E7 Proteins/genetics ; Papillomavirus E7 Proteins/metabolism
Czasopismo naukowe
Tytuł:
Inhibitors of Jumonji C domain-containing histone lysine demethylases overcome cisplatin and paclitaxel resistance in non-small cell lung cancer through APC/Cdh1-dependent degradation of CtIP and PAF15.
Autorzy:
Duan L; Department of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, USA.
Perez RE; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA.
Calhoun S; Department of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, USA.
Maki CG; Department of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, USA.
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Źródło:
Cancer biology & therapy [Cancer Biol Ther] 2022 Dec 31; Vol. 23 (1), pp. 65-75.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Antigens, CD ; Cadherins ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Histone Demethylases/genetics ; Histone Demethylases/metabolism ; Humans ; Jumonji Domain-Containing Histone Demethylases/genetics ; Jumonji Domain-Containing Histone Demethylases/metabolism ; Lysine ; Paclitaxel/pharmacology ; Paclitaxel/therapeutic use
Czasopismo naukowe
Tytuł:
Tailored modulation of stemness and drug resistance marker characteristics in K-Ras mutant lung cancer cells via PD-L1 gene suppression.
Autorzy:
Unver N; Hacettepe University, Cancer Institute, Department of Basic Oncology, Sihhiye, Ankara 06100, Turkey. Electronic address: .
Tavukcuoglu E; Hacettepe University, Cancer Institute, Department of Basic Oncology, Sihhiye, Ankara 06100, Turkey.
Esendagli G; Hacettepe University, Cancer Institute, Department of Basic Oncology, Sihhiye, Ankara 06100, Turkey.
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Źródło:
Life sciences [Life Sci] 2022 Dec 15; Vol. 311 (Pt B), pp. 121171. Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Humans ; Adenosine Triphosphate ; B7-H1 Antigen/genetics ; Biomarkers ; Drug Resistance ; Ligands ; Neoplastic Stem Cells
Czasopismo naukowe
Tytuł:
Generation of genetically engineered mice for lung cancer with mutant EGFR.
Autorzy:
Kim DS; Department of Biomedical Sciences, Asan Medical Center, AMIST, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Ji W; Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Kim DH; Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Choi YJ; Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Im K; Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Lee CW; Department of Biomedical Sciences, Asan Medical Center, AMIST, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Cho J; Department of Biomedical Sciences, Asan Medical Center, AMIST, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Min J; Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Woo DC; Department of Convergence Medicine, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Choi CM; Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea; Department of Oncology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Lee JC; Department of Oncology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea.
Sung YH; Department of Convergence Medicine, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea. Electronic address: .
Rho JK; Department of Convergence Medicine, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, 05505, South Korea. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Dec 03; Vol. 632, pp. 85-91. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
ErbB Receptors*/genetics
ErbB Receptors*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Animals ; Humans ; Mice ; Aniline Compounds/pharmacology ; Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Luciferases, Firefly/genetics ; Mutation ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
AZ12756122, a novel fatty acid synthase inhibitor, decreases resistance features in EGFR-TKI resistant EGFR-mutated NSCLC cell models.
Autorzy:
Polonio-Alcalá E; New Therapeutic Targets Laboratory (TargetsLab)-Oncology Unit, Department of Medical Sciences, University of Girona, Spain; Product, Process and Production Engineering Research Group (GREP), Department of Mechanical Engineering and Industrial Construction, University of Girona, Spain. Electronic address: .
Porta R; New Therapeutic Targets Laboratory (TargetsLab)-Oncology Unit, Department of Medical Sciences, University of Girona, Spain; Medical Oncology Department, Catalan Institute of Oncology, Spain. Electronic address: .
Ruiz-Martínez S; New Therapeutic Targets Laboratory (TargetsLab)-Oncology Unit, Department of Medical Sciences, University of Girona, Spain. Electronic address: .
Vásquez-Dongo C; New Therapeutic Targets Laboratory (TargetsLab)-Oncology Unit, Department of Medical Sciences, University of Girona, Spain; Department of Pathology, Dr. Josep Trueta University Hospital, Spain. Electronic address: .
Relat J; Department of Nutrition, Food Sciences and Gastronomy, School of Pharmacy and Food Sciences, Food Torribera Campus, University of Barcelona, Spain; Institute of Nutrition and Food Safety of the University of Barcelona (INSA-UB), Spain; CIBER Physiopathology of Obesity and Nutrition (CIBER-OBN), Instituto de Salud Carlos III, Spain. Electronic address: .
Bosch-Barrera J; Medical Oncology Department, Catalan Institute of Oncology, Spain. Electronic address: .
Ciurana J; Product, Process and Production Engineering Research Group (GREP), Department of Mechanical Engineering and Industrial Construction, University of Girona, Spain. Electronic address: .
Puig T; New Therapeutic Targets Laboratory (TargetsLab)-Oncology Unit, Department of Medical Sciences, University of Girona, Spain. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Dec; Vol. 156, pp. 113942. Date of Electronic Publication: 2022 Oct 28.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Humans ; Proto-Oncogene Proteins c-akt/metabolism ; Drug Resistance, Neoplasm ; Neoplasm Recurrence, Local ; ErbB Receptors/genetics ; Protein Kinase Inhibitors/pharmacology ; Fatty Acid Synthases ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC.
Autorzy:
Li S; Department of Oncology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK-Shenzhen research Institute, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: .
Zhu S; Department of Oncology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
Wei H; Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China. Electronic address: .
Zhu P; Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: zpf_.
Jiao Y; Department of Oncology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Institute of Digestive Disease and Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK-Shenzhen research Institute, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: .
Yi M; Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China. Electronic address: .
Gong J; Department of Oncology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
Zheng K; Department of Oncology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
Zhang L; Department of Oncology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Dec; Vol. 156, pp. 113959. Date of Electronic Publication: 2022 Nov 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; ErbB Receptors/metabolism ; Drug Resistance, Neoplasm/genetics ; Mutation
Czasopismo naukowe
Tytuł:
First-line combined therapy improves metastatic non-small cell lung cancer survival regardless of mutational status.
Źródło:
Cancer [Cancer] 2022 Dec 01; Vol. 128 (23), pp. 4039.
Typ publikacji:
Wiadomości
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Humans ; Mutation ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use
Periodyk
Tytuł:
Mechanism of METTL14-mediated m A modification in non-small cell lung cancer cell resistance to cisplatin.
Autorzy:
Gong S; Department of Thoracic Surgery, First Affiliated Hospital of China Medical University, Liaoning Province, Shenyang, 110001, People's Republic of China.
Wang S; Department of Geriatric Surgery, First Affiliated Hospital of China Medical University, Liaoning Province, Shenyang, 110001, People's Republic of China.
Shao M; Department of Thoracic Surgery, First Affiliated Hospital of China Medical University, Liaoning Province, Shenyang, 110001, People's Republic of China. .
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Źródło:
Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2022 Dec; Vol. 100 (12), pp. 1771-1785. Date of Electronic Publication: 2022 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Methyltransferases*/genetics
Methyltransferases*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Proliferation ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Drug Resistance, Neoplasm/genetics ; RNA-Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
Harnessing mitochondrial metabolism and drug resistance in non-small cell lung cancer and beyond by blocking heat-shock proteins.
Autorzy:
Parma B; Interdisciplinary Center for Clinical Research (IZKF), Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany.
Wurdak H; Stem Cell and Brain Tumour Group, School of Medicine, University of Leeds, Leeds LS2 9JT, UK. Electronic address: .
Ceppi P; Interdisciplinary Center for Clinical Research (IZKF), Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen, Germany; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark. Electronic address: .
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Źródło:
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy [Drug Resist Updat] 2022 Dec; Vol. 65, pp. 100888. Date of Electronic Publication: 2022 Oct 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Humans ; Heat-Shock Proteins/genetics ; Heat-Shock Proteins/metabolism ; Heat-Shock Proteins/therapeutic use ; Mitochondria ; Drug Resistance
Czasopismo naukowe
Tytuł:
Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC.
Autorzy:
Cristina M; Department of Life and Environmental Sciences, Marche Polytechnic University, 60131 Ancona, Italy. Electronic address: .
Emiliano L; Department of Science and Engineering of Matter, Environment and Urban Planning, Marche Polytechnic University, 60131 Ancona, Italy. Electronic address: .
Leonardo S; Department of Science and Engineering of Matter, Environment and Urban Planning, Marche Polytechnic University, 60131 Ancona, Italy. Electronic address: .
Giulia S; Department of Life and Environmental Sciences, Marche Polytechnic University, 60131 Ancona, Italy. Electronic address: .
Roberta G; Department of Life and Environmental Sciences, Marche Polytechnic University, 60131 Ancona, Italy. Electronic address: .
Adolfo A; Department of Clinical Sciences, Section of Biochemistry, Biology and Physics, U Marche Polytechnic University, 60131 Ancona, Italy. Electronic address: .
Marta SS; Protein Facility, Structural Biology Lab, Elettra Sincrotrone Trieste S.C.p.A., 34149 Basovizza, Trieste, Italy. Electronic address: .
Paola S; Protein Facility, Structural Biology Lab, Elettra Sincrotrone Trieste S.C.p.A., 34149 Basovizza, Trieste, Italy. Electronic address: .
Samuele R; Department of Life and Environmental Sciences, Marche Polytechnic University, 60131 Ancona, Italy. Electronic address: .
Pierluigi S; Department of Science and Engineering of Matter, Environment and Urban Planning, Marche Polytechnic University, 60131 Ancona, Italy. Electronic address: .
Massimo M; Department of Chemistry G. Ciamician, University of Bologna, Via Selmi 2, Bologna 40126, Italy. Electronic address: .
Giovanna M; Department of Life and Environmental Sciences, Marche Polytechnic University, 60131 Ancona, Italy. Electronic address: .
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2022 Dec; Vol. 129, pp. 106219. Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Flavones*/pharmacology
Flavones*/therapeutic use
Humans ; ErbB Receptors ; Protein Kinase Inhibitors/chemistry ; Mutation ; Drug Resistance, Neoplasm
Czasopismo naukowe
Tytuł:
PD-1 inhibitors plus chemotherapy in EGFR/ALK-positive NSCLC patients with brain metastases and disease progression after EGFR/ALK-TKIs therapy.
Autorzy:
Zhu Y; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Zhang Y; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.; Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Hu X; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Wang M; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Wang H; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Liu Y; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. .
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Źródło:
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2022 Dec; Vol. 148 (12), pp. 3557-3566. Date of Electronic Publication: 2022 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Brain Neoplasms*/drug therapy
Brain Neoplasms*/genetics
Brain Neoplasms*/secondary
Humans ; Anaplastic Lymphoma Kinase/genetics ; Immune Checkpoint Inhibitors ; Bevacizumab/therapeutic use ; Retrospective Studies ; Mutation ; Protein Kinase Inhibitors ; ErbB Receptors/genetics ; Disease Progression
Czasopismo naukowe
Tytuł:
Relation of overall tumor burden with severe immune-related adverse events in nivolumab plus ipilimumab treatment for lung cancer.
Autorzy:
Sumi T; Department of Pulmonary Medicine, Hakodate Goryoukaku Hospital, 38-3 Goryoukaku-Cho, Hakodate-shi, 040-8611, Hokkaido, Hokkaido, Japan. .; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan. .
Sekikawa M; Department of Pulmonary Medicine, Hakodate Goryoukaku Hospital, 38-3 Goryoukaku-Cho, Hakodate-shi, 040-8611, Hokkaido, Hokkaido, Japan.; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Nagahisa Y; Department of Pulmonary Medicine, Hakodate Goryoukaku Hospital, 38-3 Goryoukaku-Cho, Hakodate-shi, 040-8611, Hokkaido, Hokkaido, Japan.; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Matsuura K; Department of Pulmonary Medicine, Hakodate Goryoukaku Hospital, 38-3 Goryoukaku-Cho, Hakodate-shi, 040-8611, Hokkaido, Hokkaido, Japan.; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Shijubou N; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Kamada K; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Watanabe H; Department of Pulmonary Medicine, Hakodate Goryoukaku Hospital, 38-3 Goryoukaku-Cho, Hakodate-shi, 040-8611, Hokkaido, Hokkaido, Japan.
Yamada Y; Department of Pulmonary Medicine, Hakodate Goryoukaku Hospital, 38-3 Goryoukaku-Cho, Hakodate-shi, 040-8611, Hokkaido, Hokkaido, Japan.
Tanaka Y; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Chiba H; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan.
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Źródło:
Investigational new drugs [Invest New Drugs] 2022 Dec; Vol. 40 (6), pp. 1315-1321. Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:
Journal Article
MeSH Terms:
Lung Neoplasms*/pathology
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/pathology
Humans ; Nivolumab/adverse effects ; Ipilimumab/adverse effects ; Tumor Burden ; Retrospective Studies
Czasopismo naukowe
Tytuł:
Consistency and prognostic value of preoperative staging and postoperative pathological staging using F-FDG PET/MRI in patients with non-small cell lung cancer.
Autorzy:
Kajiyama A; Department of Radiology, Toho University Graduate School of Medicine, Tokyo, Japan.; Department of Diagnostic Radiology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Ito K; Department of Diagnostic Radiology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan. .
Watanabe H; Department of Diagnostic Radiology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
Mizumura S; Department of Radiology, Toho University Omori Medical Center, Tokyo, Japan.
Watanabe SI; Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan.
Yatabe Y; Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan.
Gomi T; Department of Radiology, Toho University Ohashi Medical Center, Tokyo, Japan.
Kusumoto M; Department of Diagnostic Radiology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
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Źródło:
Annals of nuclear medicine [Ann Nucl Med] 2022 Dec; Vol. 36 (12), pp. 1059-1072. Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/diagnostic imaging
Carcinoma, Non-Small-Cell Lung*/surgery
Lung Neoplasms*/diagnostic imaging
Lung Neoplasms*/surgery
Humans ; Fluorodeoxyglucose F18 ; Prognosis ; Retrospective Studies ; Radiopharmaceuticals ; Positron-Emission Tomography ; Neoplasm Staging ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł:
ALK TKI therapy in patients with ALK-positive non-small cell lung cancer and brain metastases: A review of the literature and local experiences.
Autorzy:
Cicin I; Trakya University, Faculty of Medicine, Department of Medical Oncology, Balkan Oncology Hospital, 22030 Edirne, Turkey. Electronic address: .
Martin C; Alexander Fleming Institution, Cramer 1180 caba, Buenos Aires CP 1426, Argentina. Electronic address: .
Haddad CK; Thoracic Oncology Department, DASA Group, Hospital Nove de Julho, Rua Peixoto Gomide, 545 - 4th floor, Build B, 01409-002 São Paulo, SP, Brazil. Electronic address: .
Kim SW; Asan Medical Center, 88, Olympic-ro, 43-gil, Songpa-gu, Seoul 05505, South Korea. Electronic address: .
Smolin A; Burdenko Main Military Hospital, Radiation Oncology Center, Gospitalnaya pl.3, Moscow 105094, Russia. Electronic address: .
Abdillah A; Takeda Pharmaceuticals International AG, 8 Marina Boulevard, #15-01, Marina Bay Financial Centre, 018981, Singapore. Electronic address: .
Yang X; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Medical Oncology, Peking University Cancer Hospital and Institute, Fucheng Road No.52 Haidian District, Beijing 100142, China. Electronic address: .
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Źródło:
Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2022 Dec; Vol. 180, pp. 103847. Date of Electronic Publication: 2022 Oct 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Brain Neoplasms*/drug therapy
Brain Neoplasms*/secondary
Humans ; Crizotinib/therapeutic use ; Anaplastic Lymphoma Kinase/genetics ; Protein Kinase Inhibitors/therapeutic use ; Protein Kinase Inhibitors/pharmacology
Czasopismo naukowe
Tytuł:
Two missense variants of the epidermal growth factor receptor gene are associated with non small cell lung carcinoma in the subjects from Iraq.
Autorzy:
Lawi ZK; Department of Biology, College of Science, University of Kufa, Najaf, 54001, Iraq.
Al-Shuhaib MBS; Department of Animal Production, College of Agriculture, Al-Qasim Green University, Al-Qasim, Babil, 51001, Iraq. .
Amara IB; Laboratory of Medicinal and Environment Chemistry, Higher Institute of Biotechnology, University of SFAX, PB 261, 3000, Sfax, Tunisia.
Alkhammas AH; Department of Animal Production, College of Agriculture, Al-Qasim Green University, Al-Qasim, Babil, 51001, Iraq.
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Źródło:
Molecular biology reports [Mol Biol Rep] 2022 Dec; Vol. 49 (12), pp. 11653-11661. Date of Electronic Publication: 2022 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/pathology
Humans ; Iraq ; Genes, erbB-1 ; Case-Control Studies ; ErbB Receptors/genetics
Czasopismo naukowe
Tytuł:
Asian Thoracic Oncology Research Group (ATORG) Expert Consensus Statement on MET Alterations in NSCLC: Diagnostic and Therapeutic Considerations.
Autorzy:
Ahn MJ; Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Mendoza MJL; Section of Medical Oncology, St. Luke's Medical Center - Global City, Philippines.
Pavlakis N; Department of Medical Oncology, Royal North Shore Hospital, University of Sydney, Sydney, NSW, Australia.
Kato T; Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan.
Soo RA; Department of Haematology-Oncology, National University Cancer Institute Singapore, Singapore.
Kim DW; Department of Internal Medicine, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, Republic of Korea.
Liam CK; Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Hsia TC; Department of Respiratory Therapy, China Medical University, Taichung, Taiwan; Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
Lee CK; National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, Sydney, NSW, Australia.
Reungwetwattana T; Division of Medical Oncology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Geater S; Division of Internal Medicine, Faculty of Medicine, Songklanagarind Hospital, Prince of Songkla University, Songkhla, Thailand.
Chan OSH; Department of Clinical Oncology, Hong Kong Integrated Oncology Centre, Hong Kong SAR, China.
Prasongsook N; Division of Medical Oncology, Department of Medicine, Phramongkutklao Hospital, Bangkok, Thailand.
Solomon BJ; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Nguyen TTH; Department of Medical Oncology, National Cancer Hospital, Hanoi, Vietnam.
Kozuki T; Department of Thoracic Oncology and Medicine, National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime, Japan.
Yang JC; Department of Medical Oncology, National Taiwan University Cancer Center and National Taiwan University Hospital, Taipei, Taiwan.
Wu YL; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Mok TSK; Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China.
Tan DS; Division of Medical Oncology, National Cancer Centre Singapore, Singapore. Electronic address: .
Yatabe Y; Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan.
Pokaż więcej
Źródło:
Clinical lung cancer [Clin Lung Cancer] 2022 Dec; Vol. 23 (8), pp. 670-685. Date of Electronic Publication: 2022 Aug 23.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/diagnosis
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/diagnosis
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Epithelial-Mesenchymal Transition*
Humans ; Drug Resistance, Neoplasm/genetics ; ErbB Receptors/genetics ; Mutation ; Protein Kinase Inhibitors/therapeutic use ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-met
Czasopismo naukowe
Tytuł:
Prognostic impact of the tumor volume doubling time in clinical T1 non-small cell lung cancer with solid radiological findings.
Autorzy:
Nakahashi K; Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Yamagata, Japan.
Shiono S; Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Yamagata, Japan.
Nakatsuka M; Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Yamagata, Japan.
Endo M; Department of Thoracic Surgery, Yamagata Prefectural Central Hospital, Yamagata, Yamagata, Japan.
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Źródło:
Journal of surgical oncology [J Surg Oncol] 2022 Dec; Vol. 126 (7), pp. 1330-1340. Date of Electronic Publication: 2022 Aug 03.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/diagnostic imaging
Carcinoma, Non-Small-Cell Lung*/surgery
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/diagnostic imaging
Lung Neoplasms*/surgery
Lung Neoplasms*/pathology
Humans ; Prognosis ; Fluorodeoxyglucose F18 ; Tumor Burden ; Retrospective Studies ; Positron-Emission Tomography ; Neoplasm Staging
Czasopismo naukowe
Tytuł:
Non-adjacent interlobar lymph node metastasis distant from small-sized peripheral non-small cell lung cancer.
Autorzy:
Maniwa T; Department of General Thoracic Surgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan. .; Department of Oncology, Graduate School of Medicine, Osaka University, Osaka, Japan. .
Kimura T; Department of General Thoracic Surgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan.
Ohue M; Department of Oncology, Graduate School of Medicine, Osaka University, Osaka, Japan.
Shintani Y; Department of General Thoracic Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan.
Okami J; Department of General Thoracic Surgery, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan.
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Źródło:
Surgery today [Surg Today] 2022 Dec; Vol. 52 (12), pp. 1746-1752. Date of Electronic Publication: 2022 Apr 30.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/surgery
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/surgery
Lung Neoplasms*/pathology
Humans ; Lymphatic Metastasis/pathology ; Retrospective Studies ; Neoplasm Staging ; Lymph Nodes/pathology ; Lymph Node Excision/methods ; Chronic Disease ; Pneumonectomy
Czasopismo naukowe
Tytuł:
Phase I study of lurbinectedin in combination with weekly paclitaxel with or without bevacizumab in patients with advanced solid tumors.
Autorzy:
Calvo E; START Madrid - HM CIOCC, Hospital Madrid Norte Sanchinarro, Madrid, Spain.
Sessa C; Oncology Institute of Southern Switzerland, EOC, Ospedale San Giovanni, Bellinzona, Switzerland.
Harada G; Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA.
de Miguel M; START Madrid - HM CIOCC, Hospital Madrid Norte Sanchinarro, Madrid, Spain.
Kahatt C; PharmaMar, Colmenar Viejo, Madrid, Spain.
Luepke-Estefan XE; PharmaMar, Colmenar Viejo, Madrid, Spain.
Siguero M; PharmaMar, Colmenar Viejo, Madrid, Spain.
Fernandez-Teruel C; PharmaMar, Colmenar Viejo, Madrid, Spain.
Cullell-Young M; PharmaMar, Colmenar Viejo, Madrid, Spain.
Stathis A; Oncology Institute of Southern Switzerland, EOC, Ospedale San Giovanni, Bellinzona, Switzerland.
Drilon A; Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA. .
Pokaż więcej
Źródło:
Investigational new drugs [Invest New Drugs] 2022 Dec; Vol. 40 (6), pp. 1263-1273. Date of Electronic Publication: 2022 Aug 10.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Antineoplastic Combined Chemotherapy Protocols*/adverse effects
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/pathology
Endometrial Neoplasms*/drug therapy
Endometrial Neoplasms*/pathology
Lung Neoplasms*/drug therapy
Lung Neoplasms*/pathology
Female ; Humans ; Bevacizumab/therapeutic use ; Paclitaxel/therapeutic use
Czasopismo naukowe
Tytuł:
Pralsetinib and Sequential MET Inhibitors to Overcome MET Amplification Resistance in a Patient With a RET Fusion Driven Lung Cancer - Case Report.
Autorzy:
Wang P; Department of Pulmonology and Thoracic Oncology, Tenon Hospital, Assistance Publique Hôpitaux de Paris and GRC 4, Theranoscan, Sorbonne Université, Paris, France.
Matton L; Department of Pulmonology and Thoracic Oncology, Tenon Hospital, Assistance Publique Hôpitaux de Paris and GRC 4, Theranoscan, Sorbonne Université, Paris, France.
Kebir F; Pathology Department, Tenon Hospital, AP-HP, Groupe Hospitalier HUEP, Paris, France.
Kerrou K; Department of Nuclear Medicine, Tenon Hospital, AP-HP, Sorbonne University, Paris, France.
Dubois A; Department of Pharmacy, Tenon Hospital, AP-HP, Sorbonne University, Paris, France.
Lacave R; Solid Tumours Genomics Unit, Tenon Hospital, AP-HP, Sorbonne University, Paris, France.
Cadranel J; Department of Pulmonology and Thoracic Oncology, Tenon Hospital, Assistance Publique Hôpitaux de Paris and GRC 4, Theranoscan, Sorbonne Université, Paris, France.
Fallet V; Department of Pulmonology and Thoracic Oncology, Tenon Hospital, Assistance Publique Hôpitaux de Paris and GRC 4, Theranoscan, Sorbonne Université, Paris, France. Electronic address: .
Pokaż więcej
Źródło:
Clinical lung cancer [Clin Lung Cancer] 2022 Dec; Vol. 23 (8), pp. e568-e572. Date of Electronic Publication: 2022 Aug 20.
Typ publikacji:
Case Reports
MeSH Terms:
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Humans ; Pyrazoles/therapeutic use ; Pyridines ; Protein Kinase Inhibitors/therapeutic use ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-ret/genetics
Raport

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