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Wyszukujesz frazę ""Carcinoma, Non-Small-Cell Lung"" wg kryterium: Temat


Tytuł :
The rapidly evolving landscape of novel targeted therapies in advanced non-small cell lung cancer.
Autorzy :
Melosky B; Medical Oncology, BCCA - 600 W 10th Ave, Vancouver, BC, V5Z 4E6, Canada. Electronic address: .
Wheatley-Price P; Ottawa Hospital Research Institute, University of Ottawa, 501 Smyth Box 511, Ottawa, ON, K1H 8L6, Canada.
Juergens RA; Juravinski Cancer Centre, McMaster University, 699 Concession Street, Hamilton, ON, L8V5C2, Canada.
Sacher A; Princess Margaret Cancer Centre, University of Toronto, 101 College Street, Toronto, ON, M5G1L7, Canada.
Leighl NB; Princess Margaret Cancer Centre, University of Toronto, 7-913 700 University Avenue, Toronto, ON, M5G1Z5, Canada.
Tsao MS; Princess Margaret Cancer Centre, University of Toronto, 101 College Street, Toronto, ON, M5G1L7, Canada.
Cheema P; William Osler Health System, University of Toronto, 101 Humber College Blvd, Etobicoke, ON, M9V 1R8, Canada.
Snow S; QEII Health Sciences Centre, Dalhousie University, 1276 South Park Street Halifax, NS, B3H 2Y9, Canada.
Liu G; Princess Margaret Cancer Centre, University of Toronto, 101 College Street, Toronto, ON, M5G1L7, Canada.
Card PB; Kaleidoscope Strategic Inc., 146 Marion St., Toronto, ON, M6R 1E7, Canada.
Chu Q; Cross Cancer Institute, University of Alberta, 11560 University Ave, 2nd Floor, Edmonton, AB, T6G 1Z2, Canada.
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Źródło :
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2021 Oct; Vol. 160, pp. 136-151. Date of Electronic Publication: 2021 Jun 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Humans ; Molecular Targeted Therapy ; Protein-Tyrosine Kinases ; Proto-Oncogene Proteins/therapeutic use
Czasopismo naukowe
Tytuł :
Major breakthroughs in lung cancer adjuvant treatment: Looking beyond the horizon.
Autorzy :
Passiglia F; Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy. Electronic address: .
Bertaglia V; Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy.
Reale ML; Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy. Electronic address: .
Delcuratolo MD; Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy.
Tabbò F; Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy.
Olmetto E; Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy.
Capelletto E; Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy. Electronic address: .
Bironzo P; Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy. Electronic address: .
Novello S; Department of Oncology, University of Turin, S. Luigi Gonzaga Hospital, Orbassano (TO), Italy. Electronic address: .
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Źródło :
Cancer treatment reviews [Cancer Treat Rev] 2021 Dec; Vol. 101, pp. 102308. Date of Electronic Publication: 2021 Oct 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/immunology
Carcinoma, Non-Small-Cell Lung*/pathology
Carcinoma, Non-Small-Cell Lung*/therapy
Chemotherapy, Adjuvant*/methods
Chemotherapy, Adjuvant*/trends
Lung Neoplasms*/immunology
Lung Neoplasms*/pathology
Lung Neoplasms*/therapy
Immune Checkpoint Inhibitors/*pharmacology
Antineoplastic Protocols/classification ; Clinical Trials as Topic ; Combined Modality Therapy/methods ; Humans ; Immunotherapy/methods ; Neoplasm Staging
Czasopismo naukowe
Tytuł :
Lobectomy With Artery Reconstruction and Pneumonectomy for Non-Small Cell Lung Cancer: A Propensity Score Weighting Study.
Autorzy :
Schiavon M; Thoracic Surgery Division, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy. Electronic address: .
Comacchio GM; Thoracic Surgery Division, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy.
Mammana M; Thoracic Surgery Division, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy.
Faccioli E; Thoracic Surgery Division, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy.
Stocca F; Thoracic Surgery Division, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy.
Gregori D; Unit of Biostatistics, Epidemiology, and Public Health, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padova, Padova, Italy.
Lorenzoni G; Unit of Biostatistics, Epidemiology, and Public Health, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padova, Padova, Italy.
Zuin A; Thoracic Surgery Division, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy.
Nicotra S; Thoracic Surgery Division, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy.
Pasello G; Medical Oncology 2, Veneto Institute of Oncology IOV IRCCS, Padova, Italy.
Calabrese F; Division of Pathology, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy.
Dell'Amore A; Thoracic Surgery Division, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy.
Rea F; Thoracic Surgery Division, Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, Padova University Hospital, Padova, Italy.
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Źródło :
The Annals of thoracic surgery [Ann Thorac Surg] 2021 Dec; Vol. 112 (6), pp. 1805-1813. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasm Staging*
Carcinoma, Non-Small-Cell Lung/*surgery
Lung Neoplasms/*surgery
Pneumonectomy/*methods
Pulmonary Artery/*surgery
Reconstructive Surgical Procedures/*methods
Vascular Surgical Procedures/*methods
Aged ; Carcinoma, Non-Small-Cell Lung/blood supply ; Carcinoma, Non-Small-Cell Lung/diagnosis ; Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Italy/epidemiology ; Lung Neoplasms/blood supply ; Lung Neoplasms/diagnosis ; Male ; Middle Aged ; Morbidity ; Postoperative Complications/epidemiology ; Propensity Score ; Reoperation ; Retrospective Studies ; Risk Factors ; Survival Rate/trends ; Treatment Outcome
Czasopismo naukowe
Tytuł :
A plain language summary of results from the ADAURA study: osimertinib after surgery for patients who have early-stage EGFR-mutated non-small cell lung cancer.
Autorzy :
Wu YL; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China.
Tsuboi M; Department of Thoracic Surgery and Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
John T; Department of Medical Oncology, Austin Health, Melbourne, Australia.
Grohe C; Department of Respiratory Diseases, Evangelische Lungenklinik, Berlin, Germany; 5Department of Medical Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Majem M; Department of Medical Oncology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Goldman JW; David Geffen School of Medicine at University of California Los Angeles, CA, USA.
Laktionov K; Center of Innovative Technologies and Oncology, N.N. Blokhin Russian Cancer Center, Russian Academy of Medical Sciences, Moscow, Russia.
Kim SW; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Kato T; Department of Thoracic Oncology, Kanagawa Cancer Center, Yokohama, Japan.
Vu HV; Department of Thoracic Surgery, Choray Hospital, Ho Chi Minh City, Vietnam.
Lu S; Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Lee KY; Precision Medicine, Lung Cancer Center, Konkuk University Medical Center, Seoul, South Korea.
Akewanlop C; Division of Medical Oncology, Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand.
Yu CJ; Department of Internal Medicine, National Taiwan University Hospital Hsinchu Branch and National Taiwan University College of Medicine, Taipei, Taiwan.
de Marinis F; Thoracic Oncology Division, European Institute of Oncology (IEO), IRCCS, Milan, Italy.
Bonanno L; Medical Oncology 2, Istituto Oncologico Veneto IOV IRCCS, Padova, Italy.
Domine M; Instituto de Investigacion Sanitaria-Fundacion de la Jimenez Diaz, Madrid, Spain.
Shepherd FA; Department of Medical Oncology and Hematology, University Health Network, Princess Margaret Hospital and the University of Toronto, Toronto, Ontario, Canada.
Zeng L; Late Oncology Statistics, AstraZeneca, Gaithersburg, MD, USA.
Hodge R; Late Oncology Statistics, AstraZeneca, Cambridge, UK.
Atasoy A; Late Oncology Research & Development, AstraZeneca, Cambridge, UK.
Rukazenkov Y; Late Oncology Research & Development, AstraZeneca, Cambridge, UK.
Herbst RS; Medical Oncology, Yale School of Medicine and Yale Cancer Center, New Haven, CT, USA.
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Źródło :
Future oncology (London, England) [Future Oncol] 2021 Dec 01; Vol. 17 (35), pp. 4827-4835. Date of Electronic Publication: 2021 Nov 01.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Acrylamides ; Aniline Compounds ; ErbB Receptors/genetics ; Humans ; Language ; Mutation
Czasopismo naukowe
Tytuł :
Mediastinal lymph node dissection for the elderly with clinical stage I non-small cell lung cancer.
Autorzy :
Katsumata S; Division of Thoracic Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Tane K; Division of Thoracic Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan. .
Suzuki J; Division of Thoracic Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Miyoshi T; Division of Thoracic Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Samejima J; Division of Thoracic Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Aokage K; Division of Thoracic Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Ishii G; Department of Pathology and Clinical Laboratories, National Cancer Center Hospital East, Kashiwa, Japan.
Tsuboi M; Division of Thoracic Surgery, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
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Źródło :
General thoracic and cardiovascular surgery [Gen Thorac Cardiovasc Surg] 2021 Dec; Vol. 69 (12), pp. 1560-1566. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/pathology
Carcinoma, Non-Small-Cell Lung*/surgery
Lung Neoplasms*/pathology
Lung Neoplasms*/surgery
Aged ; Humans ; Lymph Node Excision ; Neoplasm Recurrence, Local ; Neoplasm Staging
Czasopismo naukowe
Tytuł :
Acquired resistance in NSCLC: the journey from clinical definition to molecular understanding.
Autorzy :
Wauters E; Respiratory Oncology Unit (Pulmonology), University Hospitals KU Leuven, Leuven, Belgium; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium. Electronic address: .
Vansteenkiste J; Respiratory Oncology Unit (Pulmonology), University Hospitals KU Leuven, Leuven, Belgium; Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
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Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2021 Dec; Vol. 32 (12), pp. 1463-1465. Date of Electronic Publication: 2021 Oct 02.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Humans
Raport
Tytuł :
Selective Mediastinal Lymphadenectomy or Complete Mediastinal Lymphadenectomy for Clinical Stage I Non-Small Cell Lung Cancer: A Meta-Analysis.
Autorzy :
Luo J; Department of Thoracic Surgery, The First Hospital of China Medical University, 155 North Nanjing St, Shenyang, 110001, Liaoning, China.
Yang S; Department of Thoracic Surgery, The First Hospital of China Medical University, 155 North Nanjing St, Shenyang, 110001, Liaoning, China.
Dong S; Department of Thoracic Surgery, The First Hospital of China Medical University, 155 North Nanjing St, Shenyang, 110001, Liaoning, China. .
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Źródło :
Advances in therapy [Adv Ther] 2021 Dec; Vol. 38 (12), pp. 5671-5683. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/pathology
Carcinoma, Non-Small-Cell Lung*/surgery
Lung Neoplasms*/pathology
Lung Neoplasms*/surgery
Humans ; Lymph Node Excision ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Randomized Controlled Trials as Topic ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Phase III study of adjuvant gemcitabine compared with adjuvant uracil-tegafur in patients with completely resected pathological stage IB-IIIA non-small cell lung cancer (WJTOG0101).
Autorzy :
Yamaguchi M; Department of Thoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka City, Fukuoka, Japan.
Tada H; Department of Thoracic Surgery, Osaka City General Hospital, Osaka City, Osaka, Japan. .
Mitsudomi T; Department of Thoracic Surgery, Aichi Cancer Center, Nagoya City, Aichi, Japan.
Seto T; Department of Thoracic Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka City, Fukuoka, Japan.
Yokoi K; Department of Thoracic Surgery, Nagoya University School of Medicine, Nagoya City, Aichi, Japan.
Katakami N; Division of Pulmonary Medicine, Kobe City Medical Center General Hospital, Kobe City, Hyogo, Japan.
Nakagawa K; Department of Medical Oncology, Kinki University School of Medicine, Osakasayama City, Osaka, Japan.
Oda M; Department of Thoracic Surgery, Kanazawa University School of Medicine, Kanazawa City, Ishikawa, Japan.
Ohta M; Department of Thoracic Surgery, Osaka Habikino Medical Center, Habikino City, Osaka, Japan.
Sawa T; Department of Pulmonary Medicine, Gifu Municipal Hospital, Gifu City, Gifu, Japan.
Yamashita M; Department of Thoracic Surgery, National Hospital Organization Shikoku Cancer Center, Matsuyama City, Ehime, Japan.
Iked N; Department of Surgery, Tokyo Medical University, Shinjuku-ku, Tokyo, Japan.
Saka H; Department of Pulmonary Medicine, National Hospital Organization Nagoya Hospital, Nagoya City, Aichi, Japan.
Higashiyama M; Department of General Thoracic Surgery, Osaka International Cancer Institute, Osaka City, Osaka, Japan.
Nomori H; Department of Thoracic Surgery, School of Medicine, Kumamoto University, Kumamoto City, Kumamoto, Japan.
Semba H; Division of Respiratory Disease, Kumamoto Regional Medical Center, Kumamoto City, Kumamoto, Japan.
Negoro S; Department of Medical Oncology, Hyogo Cancer Center, Akashi City, Hyogo, Japan.
Chiba Y; Division of Biostatistics, Clinical Research Center, Kinki University School of Medicine, Osakasayama CIty, Osaka, Japan.
Shimokawa M; Department of Biostatistics, Yamaguchi University School of Medicine, Yamaguchi City, Yamaguchi, Japan.
Fukuoka M; Department of Medical Oncology, Kinki University School of Medicine, Osakasayama City, Osaka, Japan.
Nakanishi Y; Research Institute for Diseases of the Chest, Kyushu University, Fukuoka City, Fukuoka, Japan.
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Corporate Authors :
West Japan Thoracic Oncology Group (WJTOG)
Źródło :
International journal of clinical oncology [Int J Clin Oncol] 2021 Dec; Vol. 26 (12), pp. 2216-2223. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/surgery
Lung Neoplasms*/drug therapy
Lung Neoplasms*/surgery
Chemotherapy, Adjuvant ; Deoxycytidine/analogs & derivatives ; Humans ; Tegafur ; Uracil/therapeutic use
Czasopismo naukowe
Tytuł :
Early and locally advanced non-small-cell lung cancer: an update of the ESMO Clinical Practice Guidelines focusing on diagnosis, staging, systemic and local therapy.
Autorzy :
Remon J; Department of Medical Oncology, Centro Integral Oncológico Clara Campal (HM-CIOCC), Hospital HM Nou Delfos, HM Hospitales, Barcelona, Spain.
Soria JC; University Paris-Saclay and Gustave Roussy Cancer Campus, Villejuif, France.
Peters S; Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne University, Lausanne, Switzerland.
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Corporate Authors :
ESMO Guidelines Committee. Electronic address:
Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2021 Dec; Vol. 32 (12), pp. 1637-1642. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Letter
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/diagnosis
Carcinoma, Non-Small-Cell Lung*/epidemiology
Carcinoma, Non-Small-Cell Lung*/therapy
Lung Neoplasms*/diagnosis
Lung Neoplasms*/epidemiology
Lung Neoplasms*/therapy
Early Detection of Cancer ; Humans
Opinia redakcyjna
Tytuł :
Correlation between pleural tags on CT and visceral pleural invasion of peripheral lung cancer that does not appear touching the pleural surface.
Autorzy :
Onoda H; Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, 755-8505, Japan. .
Higashi M; Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, 755-8505, Japan.
Murakami T; Department of Pathology, National Hospital Organization Kanmon Medical Center, Shimonoseki, Japan.
Tao H; Department of Thoracic Surgery, Japanese Red Cross Society Himeji Hospital, Himeji, Japan.
Yokoyama S; Department of Surgery, Kurume University School of Medicine, Kurume, Japan.
Kunihiro Y; Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, 755-8505, Japan.
Kawano R; Center for Integrated Medical Research, Hiroshima University Hospital, Hiroshima, Japan.
Tanabe M; Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, 755-8505, Japan.
Tanaka N; Department of Radiology, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
Matsumoto T; Department of Radiology, National Hospital Organization Yamaguchi-Ube Medical Center, Ube, Japan.
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Źródło :
European radiology [Eur Radiol] 2021 Dec; Vol. 31 (12), pp. 9022-9029. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/diagnostic imaging
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/diagnostic imaging
Lung Neoplasms*/pathology
Humans ; Neoplasm Invasiveness/pathology ; Neoplasm Staging ; Pleura/diagnostic imaging ; Pleura/pathology ; Prognosis ; Retrospective Studies ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Plain language summary of the CROWN study comparing lorlatinib with crizotinib for people with untreated non-small cell lung cancer.
Autorzy :
Solomon BJ; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Bauer TM; Sarah Cannon Research Institute/Tennessee Oncology, PLLC, Nashville, TN, USA.
de Marinis F; European Institute of Oncology, IRCCS, Milan, Italy.
Felip E; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), IOB-Quiron, Barcelona, Spain.
Goto Y; National Cancer Center Hospital, Tokyo, Japan.
Liu G; Princess Margaret Cancer Centre, Toronto, Canada.
Mazieres J; Toulouse University Hospital, Toulouse, France.
Kim DW; Seoul National University College of Medicine and Seoul National University Hospital, Seoul, South Korea.
Mok T; State Key Laboratory of Translational Oncology, Chinese University of Hong Kong, Hong Kong.
Polli A; Pfizer, Milan, Italy.
Thurm H; Pfizer Inc., La Jolla, CA, USA.
Calella AM; Pfizer, Milan, Italy.
Peltz G; Pfizer Inc., Boston, MA, USA.
Shaw AT; Massachusetts General Hospital Cancer Center, Boston, MA, USA.
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Źródło :
Future oncology (London, England) [Future Oncol] 2021 Dec 01; Vol. 17 (34), pp. 4649-4656. Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Aminopyridines ; Anaplastic Lymphoma Kinase ; Crizotinib ; Humans ; Lactams ; Language ; Pyrazoles
Czasopismo naukowe
Tytuł :
Circular RNA circ_0001287 inhibits the proliferation, metastasis, and radiosensitivity of non-small cell lung cancer cells by sponging microRNA miR-21 and up-regulating phosphatase and tensin homolog expression.
Autorzy :
Zhang CC; Department of Respiratory, The Third People's Hospital of Linyi , Linyi, China.
Li Y; Department of Oncology, The Third People's Hospital of Linyi , Linyi, China.
Feng XZ; Department of Respiratory, The Third People's Hospital of Linyi , Linyi, China.
Li DB; Department of Thoracic Surgery, Linyi Cancer Hospital , Linyi, China.
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Źródło :
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 414-425.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
RNA, Circular*/genetics
RNA, Circular*/metabolism
RNA, Circular*/pharmacology
MicroRNAs/*genetics
PTEN Phosphohydrolase/*genetics
Cell Proliferation/drug effects ; Humans ; Lung/metabolism ; Lung/pathology ; MicroRNAs/metabolism ; Neoplasm Metastasis ; PTEN Phosphohydrolase/metabolism ; Radiation Tolerance/drug effects ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Lesion-level heterogeneity of radiologic progression in patients treated with pembrolizumab.
Autorzy :
Topp BG; Quantitative Pharmacology and Pharmacometrics, Merck & Co., Inc., Kenilworth, USA. Electronic address: .
Thiagarajan K; Quantitative Systems Pharmacology, Vantage Research, Chennai, India.
De Alwis DP; Quantitative Pharmacology and Pharmacometrics, Merck & Co., Inc., Kenilworth, USA.
Snyder A; Global Clinical Development, Merck & Co., Inc., Kenilworth, USA.
Hellmann MD; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA. Electronic address: .
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Źródło :
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2021 Dec; Vol. 32 (12), pp. 1618-1625. Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/diagnostic imaging
Carcinoma, Non-Small-Cell Lung*/drug therapy
Lung Neoplasms*/diagnostic imaging
Lung Neoplasms*/drug therapy
Antibodies, Monoclonal, Humanized ; Humans ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Development of 3-methyl/3-(morpholinomethyl)benzofuran derivatives as novel antitumor agents towards non-small cell lung cancer cells.
Autorzy :
Al-Sanea MM; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Al-Ansary GH; Department of Pharmaceutical Chemistry, Pharmacy Program, Batterejee Medical College, Jeddah, Saudi Arabia.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Elsayed ZM; Scientific Research and Innovation Support Unit, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Maklad RM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.; Institute of Drug Discovery and Development, Kafrelsheikh University, Kafrelsheikh, Egypt.
Elkaeed EB; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Ad Diriyah, Riyadh, Saudi Arabia.; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City, Cairo, Egypt.
Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
Bukhari SNA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Abdel-Aziz MM; The Regional Center for Mycology & Biotechnology, Al-Azhar University, Cairo, Egypt.
Suliman H; Department of Medical Biochemistry, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 987-999.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Development*
Antineoplastic Agents/*pharmacology
Benzofurans/*pharmacology
Carcinoma, Non-Small-Cell Lung/*drug therapy
Lung Neoplasms/*drug therapy
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Benzofurans/chemical synthesis ; Benzofurans/chemistry ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Circular RNA circ_0003028 contributes to tumorigenesis by regulating GOT2 via miR-1298-5p in non-small cell lung cancer.
Autorzy :
Guan H; Department of Thoracic Surgery, Jianhu Hospital Affiliated to Nantong University, Yancheng, China.
Sun C; Department of Thoracic Surgery, Jianhu Hospital Affiliated to Nantong University, Yancheng, China.
Gu Y; Department of Thoracic Surgery, Jianhu Hospital Affiliated to Nantong University, Yancheng, China.
Li J; Department of Thoracic Surgery, Jianhu Hospital Affiliated to Nantong University, Yancheng, China.
Ji J; Information Center, Jianhu Hospital Affiliated to Nantong University, Yancheng, China.
Zhu Y; Department of Thoracic Surgery, Jianhu Hospital Affiliated to Nantong University, Yancheng, China.
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Źródło :
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 2326-2340.
Typ publikacji :
Journal Article
MeSH Terms :
Aspartate Aminotransferases*/genetics
Aspartate Aminotransferases*/metabolism
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA, Circular*/genetics
RNA, Circular*/metabolism
Animals ; Apoptosis/genetics ; Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Lung/metabolism ; Lung/pathology ; Male ; Mice ; Mice, Nude
Czasopismo naukowe
Tytuł :
Afatinib for the treatment of advanced non-small-cell lung cancer harboring an epidermal growth factor receptor exon 18 E709_T710delinsD mutation: a case report.
Autorzy :
Van Acker L; University Hospital Ghent, Ghent, Belgium. .
Stevens D; University Hospital Ghent, Ghent, Belgium.
Vermaelen K; University Hospital Ghent, Ghent, Belgium.
Surmont V; University Hospital Ghent, Ghent, Belgium.
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Źródło :
Journal of medical case reports [J Med Case Rep] 2021 Nov 22; Vol. 15 (1), pp. 562. Date of Electronic Publication: 2021 Nov 22.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Afatinib/therapeutic use ; ErbB Receptors/genetics ; Exons/genetics ; Female ; Humans ; Middle Aged ; Mutation ; Protein Kinase Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Afatinib combined with anlotinib in the treatment of lung adenocarcinoma patient with novel HER2 mutation: a case report and review of the literature.
Autorzy :
Xu H; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Liang Q; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Xu X; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Tan S; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Wang S; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China.
Liu Y; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China. .
Liu L; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, People's Republic of China. .
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Źródło :
World journal of surgical oncology [World J Surg Oncol] 2021 Nov 18; Vol. 19 (1), pp. 330. Date of Electronic Publication: 2021 Nov 18.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Adenocarcinoma of Lung*/drug therapy
Adenocarcinoma of Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Afatinib/therapeutic use ; Aged ; Humans ; Indoles ; Male ; Mutation ; Prognosis ; Protein Kinase Inhibitors ; Quinolines ; Receptor, ErbB-2/genetics
Czasopismo naukowe
Tytuł :
Chitosan-derived nanoparticles impede signal transduction in T790M lung cancer therapy.
Autorzy :
Huang G; Department of Chemistry, Zhejiang University, Hangzhou 310028, China. .; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Chen Q; Department of Chemistry, Zhejiang University, Hangzhou 310028, China. .; Institute of Translational Medicine, and the Second Affiliated Hospital, Zhejiang University School of medicine, Hangzhou 310009, China.
Hu J; Department of Chemistry, Zhejiang University, Hangzhou 310028, China. .
Mao J; Department of Chemistry, Zhejiang University, Hangzhou 310028, China. .
He Y; Department of Chemistry, Zhejiang University, Hangzhou 310028, China. .
Bai H; Department of Chemistry, Zhejiang University, Hangzhou 310028, China. .
Tang G; Department of Chemistry, Zhejiang University, Hangzhou 310028, China. .
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Źródło :
Biomaterials science [Biomater Sci] 2021 Nov 09; Vol. 9 (22), pp. 7412-7419. Date of Electronic Publication: 2021 Nov 09.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/genetics
Chitosan*
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Nanoparticles*
Signal Transduction/*drug effects
Animals ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; ErbB Receptors/genetics ; Humans ; Mice ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/genetics ; Mutation ; Protein Kinase Inhibitors/pharmacology
Czasopismo naukowe
Tytuł :
Effectiveness of Postoperative or Preoperative Radiotherapy on Prognosis in Patients with Stage II Resectable Non-Small Cell Lung Cancer: A Retrospective Study Based on the SEER Database.
Autorzy :
Chen D; School of Public Health, Fudan University, Shanghai 200433, China.
Yu J; School of Public Health, Fudan University, Shanghai 200433, China.
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Źródło :
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2021 Nov 04; Vol. 57 (11). Date of Electronic Publication: 2021 Nov 04.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/radiotherapy
Carcinoma, Non-Small-Cell Lung*/surgery
Lung Neoplasms*/pathology
Lung Neoplasms*/radiotherapy
Lung Neoplasms*/surgery
Humans ; Neoplasm Staging ; Prognosis ; Radiotherapy, Adjuvant ; Retrospective Studies ; SEER Program
Czasopismo naukowe
Tytuł :
Impact of Checkpoint Inhibitor Immunotherapy, Primarily Pembrolizumab, on Infection Risk in Patients With Advanced Lung Cancer: A Comparative Retrospective Cohort Study.
Autorzy :
Malek AE; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Khalil M; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Hachem R; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Chaftari AM; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Fares J; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Jiang Y; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Kontoyiannis DP; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Fossella F; Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Chaftari P; Department of Emergency Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Mulanovich VE; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Viola GM; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Raad II; Department of Infectious Diseases, Infection Control, and Employee Health, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
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Źródło :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2021 Nov 02; Vol. 73 (9), pp. e2697-e2704.
Typ publikacji :
Journal Article
MeSH Terms :
Carcinoma, Non-Small-Cell Lung*/complications
Carcinoma, Non-Small-Cell Lung*/drug therapy
Lung Neoplasms*/drug therapy
Antibodies, Monoclonal, Humanized ; Humans ; Immunotherapy ; Retrospective Studies
Czasopismo naukowe

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