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Wyszukujesz frazę ""Cardiotonic Agents"" wg kryterium: Temat


Tytuł :
Advanced heart failure patients supported with ambulatory inotropic therapy: What defines success of therapy?
Autorzy :
Grubb CS; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Truby LK; Department of Medicine, Duke University Medical Center, Durham, NC.
Topkara VK; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Bohnen MS; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Yuzefpolskaya M; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
DeFilippis EM; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Kleet A; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Nakagawa S; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Haythe JH; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Axsom K; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Colombo P; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Takeda K; Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Uriel N; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Sayer G; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Garan H; Department of Medicine, Columbia University Irving Medical Center, New York, NY.
Naka Y; Department of Surgery, Columbia University Irving Medical Center, New York, NY.
Farr M; Department of Medicine, Columbia University Irving Medical Center, New York, NY. Electronic address: .
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Źródło :
American heart journal [Am Heart J] 2021 Sep; Vol. 239, pp. 11-18. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article
MeSH Terms :
Ambulatory Care*/methods
Ambulatory Care*/statistics & numerical data
Cardiotonic Agents*/administration & dosage
Cardiotonic Agents*/adverse effects
Cardiotonic Agents*/classification
Heart Failure*/diagnosis
Heart Failure*/drug therapy
Heart Failure*/mortality
Heart Failure*/physiopathology
Tachycardia, Ventricular*/etiology
Tachycardia, Ventricular*/prevention & control
Assisted Circulation/instrumentation ; Assisted Circulation/methods ; Female ; Heart Transplantation/methods ; Hospitalization/statistics & numerical data ; Humans ; Intention to Treat Analysis ; Male ; Middle Aged ; Palliative Care/methods ; Patient Acuity ; Patient Discharge ; Risk Assessment ; Severity of Illness Index ; Stroke Volume ; Survival Analysis ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Synthesis and in vivo screening of isosteviol derivatives as new cardioprotective agents.
Autorzy :
Zhang H; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, China.
Liu B; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, China.
Xu G; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, China.
Xu C; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, China.
Ou E; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, China.
Liu J; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, China.
Sun X; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, China. Electronic address: .
Zhao Y; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Jul 05; Vol. 219, pp. 113396. Date of Electronic Publication: 2021 Mar 28.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiotonic Agents/*chemical synthesis
Diterpenes, Kaurane/*chemistry
Animals ; Apoptosis/drug effects ; Cardiomyopathies/drug therapy ; Cardiomyopathies/pathology ; Cardiotonic Agents/pharmacology ; Cardiotonic Agents/therapeutic use ; Cell Survival/drug effects ; Diterpenes, Kaurane/pharmacology ; Diterpenes, Kaurane/therapeutic use ; Doxorubicin/toxicity ; Embryo, Nonmammalian/drug effects ; Embryo, Nonmammalian/physiology ; Heart/drug effects ; Heart/physiology ; Membrane Potential, Mitochondrial/drug effects ; Myocytes, Cardiac/cytology ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Rats ; Reactive Oxygen Species/metabolism ; Structure-Activity Relationship ; Zebrafish/growth & development
Czasopismo naukowe
Tytuł :
Hypotension in Preterm Infants (HIP) randomised trial.
Autorzy :
Dempsey EM; Department of Paediatric and Child Health and INFANT Research Centre, University College Cork, Cork, Ireland .
Barrington KJ; Néonatologie, Centre Hospitalier Universitaire Sainte Justine, Montreal, Quebec, Canada.
Marlow N; Institute for Womens Health, University College London, London, UK.
O'Donnell CPF; Neonatal Intensive Care Unit, The National Maternity Hospital, Dublin, Ireland.
Miletin J; Paediatric and Newborn Medicine, Coombe Women and Infants University Hospital, Dublin, Ireland.
Naulaers G; Neonatology, Katholieke Universiteit Leuven, Leuven, Belgium.
Cheung PY; Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Corcoran JD; Faculty of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
El-Khuffash AF; Faculty of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Boylan GB; Department of Paediatric and Child Health and INFANT Research Centre, University College Cork, Cork, Ireland.
Livingstone V; Department of Paediatric and Child Health and INFANT Research Centre, University College Cork, Cork, Ireland.
Pons G; Clinical Pharmacology, Groupe Hospitalier Cochin-Broca, Hôtel Dieu, AP-HP, Paris, France.
Macko J; Department of Neonatology, Tomas Bata University in Zlin, Zlin, Zlínský Kraj, Czech Republic.
Van Laere D; NICU, UZ Antwerp, Edegem, Antwerp, Belgium.
Wiedermannova H; Department of Pediatrics and Neonatal Care, Ostravska Univerzita, Ostrava, Moravskoslezský, Czech Republic.
Straňák Z; Institute for the Care of Mother and Child, Third Faculty of Medicine, Charles University, Prague, Czech Republic.
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Corporate Authors :
HIP consortium
Źródło :
Archives of disease in childhood. Fetal and neonatal edition [Arch Dis Child Fetal Neonatal Ed] 2021 Jul; Vol. 106 (4), pp. 398-403. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Infant, Extremely Premature*
Cardiotonic Agents/*therapeutic use
Dopamine/*therapeutic use
Hypotension/*drug therapy
Brain Injuries/chemically induced ; Cardiotonic Agents/administration & dosage ; Cardiotonic Agents/adverse effects ; Dopamine/administration & dosage ; Dopamine/adverse effects ; Double-Blind Method ; Gestational Age ; Humans ; Hypotension/mortality ; Infant, Newborn
Czasopismo naukowe
Tytuł :
Influence of Hyperglycemia and Diabetes on Cardioprotection by Humoral Factors Released after Remote Ischemic Preconditioning (RIPC).
Autorzy :
Torregroza C; Department of Anesthesiology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Gnaegy L; Department of Anesthesiology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Raupach A; Department of Anesthesiology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Stroethoff M; Department of Anesthesiology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Feige K; Department of Anesthesiology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
Heinen A; Institute of Cardiovascular Physiology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Universitaetsstr. 1, 40225 Duesseldorf, Germany.
Hollmann MW; Department of Anesthesiology, Amsterdam University Medical Center (AUMC), Location AMC, Meiberdreef 9, 1105 AZ Amsterdam, The Netherlands.
Huhn R; Department of Anesthesiology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 18; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiotonic Agents*
Immunity, Humoral*
Diabetes Mellitus, Experimental/*complications
Diabetes Mellitus, Type 1/*complications
Hyperglycemia/*complications
Ischemic Preconditioning, Myocardial/*methods
Myocardial Reperfusion Injury/*prevention & control
Animals ; Male ; Myocardial Reperfusion Injury/etiology ; Myocardial Reperfusion Injury/pathology ; Rats ; Rats, Wistar ; Signal Transduction
Czasopismo naukowe
Tytuł :
Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock.
Autorzy :
Mathew R; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Di Santo P; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Jung RG; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Marbach JA; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Hutson J; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Simard T; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Ramirez FD; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Harnett DT; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Merdad A; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Almufleh A; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Weng W; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Abdel-Razek O; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Fernando SM; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Kyeremanteng K; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Bernick J; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Wells GA; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Chan V; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Froeschl M; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Labinaz M; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Le May MR; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Russo JJ; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
Hibbert B; From the CAPITAL Research Group, Division of Cardiology (R.M., P.D.S., R.G.J., J.A.M., T.S., F.D.R., D.T.H., O.A.-R., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Cardiovascular Research Methods Centre (J.B., G.A.W.), and the Division of Cardiac Surgery (V.C.), University of Ottawa Heart Institute, and the Faculty of Medicine (R.M., P.D.S., R.G.J., J.H., D.T.H., W.W., O.A.-R., S.M.F., K.K., M.F., M.L., M.R.L.M., J.J.R., B.H.), the Division of Critical Care, Department of Medicine (R.M., J.H., S.M.F., K.K.), the School of Epidemiology and Public Health (P.D.S.), and the Department of Cellular and Molecular Medicine (R.G.J., T.S., B.H.), University of Ottawa, Ottawa, the Division of Cardiology, University of Toronto, Toronto (A.M.), and the Division of Cardiology, University of British Columbia, Vancouver (A.A.) - all in Canada; the Division of Critical Care, Tufts Medical Center, Boston (J.A.M.); the Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN (T.S.); and Hôpital Cardiologique du Haut Lévêque, Centre Hospitalier Universitaire Bordeaux (F.D.R.), and LIRYC (L'Institut de Rythmologie et Modélisation Cardiaque) (F.D.R.) - both in Bordeaux-Pessac, France.
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Źródło :
The New England journal of medicine [N Engl J Med] 2021 Aug 05; Vol. 385 (6), pp. 516-525.
Typ publikacji :
Comparative Study; Journal Article; Pragmatic Clinical Trial; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiotonic Agents/*therapeutic use
Dobutamine/*therapeutic use
Milrinone/*therapeutic use
Shock, Cardiogenic/*drug therapy
Adrenergic beta-Agonists/therapeutic use ; Aged ; Cardiotonic Agents/adverse effects ; Comorbidity ; Dobutamine/adverse effects ; Double-Blind Method ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Milrinone/adverse effects ; Phosphodiesterase 3 Inhibitors/therapeutic use ; Shock, Cardiogenic/mortality
Czasopismo naukowe
Tytuł :
Update on acute myocarditis.
Autorzy :
Ammirati E; 'De Gasperis' Cardio Center, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore, 3, 20162 Milan, Italy. Electronic address: .
Veronese G; 'De Gasperis' Cardio Center, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore, 3, 20162 Milan, Italy; School of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy.
Bottiroli M; 'De Gasperis' Cardio Center, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore, 3, 20162 Milan, Italy.
Wang DW; Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Cipriani M; 'De Gasperis' Cardio Center, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore, 3, 20162 Milan, Italy.
Garascia A; 'De Gasperis' Cardio Center, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore, 3, 20162 Milan, Italy.
Pedrotti P; 'De Gasperis' Cardio Center, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore, 3, 20162 Milan, Italy.
Adler ED; Division of Cardiology, Department of Medicine, University of California San Diego, San Diego, United States.
Frigerio M; 'De Gasperis' Cardio Center, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore, 3, 20162 Milan, Italy.
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Źródło :
Trends in cardiovascular medicine [Trends Cardiovasc Med] 2021 Aug; Vol. 31 (6), pp. 370-379. Date of Electronic Publication: 2020 Jun 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Heart-Assist Devices*
Myocarditis*/diagnostic imaging
Myocarditis*/etiology
Myocarditis*/immunology
Myocarditis*/therapy
Cardiotonic Agents/*therapeutic use
Prosthesis Implantation/*instrumentation
Acute Disease ; Cardiotonic Agents/adverse effects ; Decision Support Techniques ; Humans ; Immune Checkpoint Inhibitors/adverse effects ; Immunosuppressive Agents/therapeutic use ; Magnetic Resonance Imaging ; Prosthesis Implantation/adverse effects ; Risk Assessment ; Risk Factors ; Treatment Outcome ; Virus Diseases/virology
Czasopismo naukowe
Tytuł :
Niacin Increases Atherogenic Proteins in High-Density Lipoprotein of Statin-Treated Subjects.
Autorzy :
Ronsein GE; Department of Biochemistry, Sao Paulo University, Brazil (G.E.R.).
Vaisar T; Department of Medicine, University of Washington, Seattle (T.V., K.E.B., J.L.P., K.D.O., X.-Q.Z., J.W.H.).
Davidson WS; Department of Pathology and Laboratory Medicine, University of Cincinnati, OH (W.S.D.).
Bornfeldt KE; Department of Medicine, University of Washington, Seattle (T.V., K.E.B., J.L.P., K.D.O., X.-Q.Z., J.W.H.).
Probstfield JL; Department of Medicine, University of Washington, Seattle (T.V., K.E.B., J.L.P., K.D.O., X.-Q.Z., J.W.H.).
O'Brien KD; Department of Medicine, University of Washington, Seattle (T.V., K.E.B., J.L.P., K.D.O., X.-Q.Z., J.W.H.).
Zhao XQ; Department of Medicine, University of Washington, Seattle (T.V., K.E.B., J.L.P., K.D.O., X.-Q.Z., J.W.H.).
Heinecke JW; Department of Medicine, University of Washington, Seattle (T.V., K.E.B., J.L.P., K.D.O., X.-Q.Z., J.W.H.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Aug; Vol. 41 (8), pp. 2330-2341. Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Atherosclerosis/*drug therapy
Cardiotonic Agents/*therapeutic use
Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
Lipoproteins, HDL/*chemistry
Niacin/*therapeutic use
Adult ; Atherosclerosis/blood ; Cardiotonic Agents/pharmacology ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/prevention & control ; Female ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology ; Lipoproteins, HDL/blood ; Male ; Middle Aged ; Niacin/pharmacology ; Proteomics
Czasopismo naukowe
Tytuł :
8-Formylophiopogonanone B antagonizes doxorubicin-induced cardiotoxicity by suppressing heme oxygenase-1-dependent myocardial inflammation and fibrosis.
Autorzy :
Qin D; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Yue R; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Deng P; Department of Occupational Health, Third Military Medical University, Chongqing 400038, China.
Wang X; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Zheng Z; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Lv M; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Zhang Y; Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China.
Pu J; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Xu J; Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China.
Liang Y; School of Medicine, Guangxi University, Nanning, Guangxi Zhuang Autonomous Region 530004, China.
Pi H; Academician Workstation, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China; Department of Occupational Health, Third Military Medical University, Chongqing 400038, China.
Yu Z; Department of Occupational Health, Third Military Medical University, Chongqing 400038, China.
Hu H; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China; Academician Workstation, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Aug; Vol. 140, pp. 111779. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*
Doxorubicin*
Cardiotonic Agents/*therapeutic use
Cardiotoxicity/*drug therapy
Heme Oxygenase-1/*antagonists & inhibitors
Membrane Proteins/*antagonists & inhibitors
Animals ; Cardiotonic Agents/pharmacology ; Cardiotoxicity/genetics ; Cardiotoxicity/metabolism ; Cardiotoxicity/pathology ; Cytokines/genetics ; Fibrosis ; Heme Oxygenase-1/genetics ; Heme Oxygenase-1/metabolism ; Inflammation/drug therapy ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Male ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Myocardium/metabolism ; Myocardium/pathology
Czasopismo naukowe
Tytuł :
Evidences for the mechanism of Shenmai injection antagonizing doxorubicin-induced cardiotoxicity.
Autorzy :
Wu YP; The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.
Zhang S; Hangzhou Medical college, Hangzhou, China.
Xin YF; Zhejiang University of Technology, Hangzhou, China.
Gu LQ; Hangzhou Medical college, Hangzhou, China.
Xu XZ; Hangzhou Medical college, Hangzhou, China.
Zhang CD; Hangzhou Medical college, Hangzhou, China.
You ZQ; Hangzhou Medical college, Hangzhou, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Jul 15; Vol. 88, pp. 153597. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiotonic Agents/*pharmacology
Cardiotoxicity/*drug therapy
Doxorubicin/*adverse effects
Drugs, Chinese Herbal/*pharmacology
Animals ; Antibiotics, Antineoplastic/adverse effects ; Apoptosis/drug effects ; Autophagy/drug effects ; Beclin-1/metabolism ; Cardiotonic Agents/administration & dosage ; Cardiotoxicity/metabolism ; Cell Line ; Drug Combinations ; Drugs, Chinese Herbal/administration & dosage ; Humans ; Injections ; JNK Mitogen-Activated Protein Kinases/metabolism ; Male ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Oxidative Stress/drug effects ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Identification of novel SIRT1 activators endowed with cardioprotective profile.
Autorzy :
Flori L; Department of Pharmacy, University of Pisa, Via Bonanno, 6, I-56126 Pisa, Italy.
Petrarolo G; Department of Pharmacy, University of Pisa, Via Bonanno, 6, I-56126 Pisa, Italy.
Brogi S; Department of Pharmacy, University of Pisa, Via Bonanno, 6, I-56126 Pisa, Italy. Electronic address: .
La Motta C; Department of Pharmacy, University of Pisa, Via Bonanno, 6, I-56126 Pisa, Italy. Electronic address: .
Testai L; Department of Pharmacy, University of Pisa, Via Bonanno, 6, I-56126 Pisa, Italy. Electronic address: .
Calderone V; Department of Pharmacy, University of Pisa, Via Bonanno, 6, I-56126 Pisa, Italy.
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2021 Oct 01; Vol. 165, pp. 105930. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiotonic Agents*/pharmacology
Cardiotonic Agents*/therapeutic use
Sirtuin 1*
Animals ; Molecular Docking Simulation ; Rats ; Resveratrol ; Small Molecule Libraries
Czasopismo naukowe
Tytuł :
Dietary Flavonoids: Cardioprotective Potential with Antioxidant Effects and Their Pharmacokinetic, Toxicological and Therapeutic Concerns.
Autorzy :
Khan J; Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia.
Deb PK; Life Sciences Division, Institute of Advanced Study in Science and Technology, Guwahati 781035, Assam, India.; Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Jharkhand, India.
Priya S; University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh 160014, India.
Medina KD; Food Technology Unit, Centre for Research and Assistance in Technology and Design of Jalisco State A.C., Camino Arenero 1227, El Bajío del Arenal, Zapopan 45019, Jalisco, Mexico.
Devi R; Life Sciences Division, Institute of Advanced Study in Science and Technology, Guwahati 781035, Assam, India.
Walode SG; Rasiklal M. Dhariwal Institute of Pharmaceutical Education & Research, Chinchwad, Pune 411019, Maharashtra, India.
Rudrapal M; Rasiklal M. Dhariwal Institute of Pharmaceutical Education & Research, Chinchwad, Pune 411019, Maharashtra, India.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 30; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antioxidants*/chemistry
Antioxidants*/pharmacokinetics
Antioxidants*/therapeutic use
Cardiotonic Agents*/chemistry
Cardiotonic Agents*/pharmacokinetics
Cardiovascular Diseases*/metabolism
Cardiovascular Diseases*/pathology
Cardiovascular Diseases*/prevention & control
Flavonoids*/chemistry
Flavonoids*/pharmacokinetics
Flavonoids*/therapeutic use
Fruit/*chemistry
Vegetables/*chemistry
Biological Availability ; Humans
Czasopismo naukowe
Tytuł :
Cardioprotective Effects of PPARβ/δ Activation against Ischemia/Reperfusion Injury in Rat Heart Are Associated with ALDH2 Upregulation, Amelioration of Oxidative Stress and Preservation of Mitochondrial Energy Production.
Autorzy :
Papatheodorou I; Laboratory of Animal Physiology, Department of Zoology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Galatou E; Laboratory of Animal Physiology, Department of Zoology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Panagiotidis GD; Laboratory of Animal Physiology, Department of Zoology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Ravingerová T; Institute for Heart Research, Centre of Experimental Medicine, Slovak Academy of Sciences, 9 Dúbravská cesta, 84104 Bratislava, Slovakia.
Lazou A; Laboratory of Animal Physiology, Department of Zoology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 15; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Energy Metabolism*/drug effects
Oxidative Stress*/drug effects
Aldehyde Dehydrogenase, Mitochondrial/*metabolism
Cardiotonic Agents/*therapeutic use
Mitochondria, Heart/*metabolism
Myocardial Reperfusion Injury/*metabolism
PPAR delta/*metabolism
PPAR-beta/*metabolism
Angiopoietin-like 4 Protein/metabolism ; Animals ; Antioxidants/metabolism ; Cadherins/metabolism ; Cardiotonic Agents/administration & dosage ; Cardiotonic Agents/pharmacology ; Catalase/metabolism ; Male ; Mitochondria, Heart/drug effects ; Models, Biological ; Myocardial Reperfusion Injury/drug therapy ; Myocardial Reperfusion Injury/pathology ; Myocardium/metabolism ; Myocardium/pathology ; PPAR delta/agonists ; PPAR-beta/agonists ; Rats, Wistar ; Superoxide Dismutase/metabolism ; Thiazoles/administration & dosage ; Thiazoles/pharmacology ; Thiazoles/therapeutic use ; Uncoupling Protein 3/metabolism ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Protective effects of myrrh essential oil on isoproterenol-induced myocardial infarction in rats through antioxidant, anti-inflammatory, Nrf2/HO-1 and apoptotic pathways.
Autorzy :
Younis NS; BCPS, Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, 31982 Al-Ahsa, Saudi Arabia; Department of Pharmacology, Zagazig University, Zagazig 44519, Egypt. Electronic address: .
Mohamed ME; BCPS, Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, 31982 Al-Ahsa, Saudi Arabia; Department of Pharmacognosy, College of Pharmacy, Zagazig University, Zagazig 44519, Egypt. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Apr 24; Vol. 270, pp. 113793. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Antioxidants/*pharmacology
Apoptosis/*drug effects
Cardiotonic Agents/*pharmacology
Myocardial Infarction/*prevention & control
Signal Transduction/*drug effects
Terpenes/*pharmacology
Animals ; Anti-Inflammatory Agents/therapeutic use ; Antioxidants/therapeutic use ; Biomarkers/metabolism ; Blood Pressure/drug effects ; Cardiotonic Agents/chemistry ; Cardiotonic Agents/therapeutic use ; Commiphora/chemistry ; Heme Oxygenase (Decyclizing)/metabolism ; Inflammation/chemically induced ; Inflammation/drug therapy ; Isoproterenol/toxicity ; Lipid Peroxidation/drug effects ; Medicine, Traditional ; Myocardial Infarction/chemically induced ; Myocardial Infarction/metabolism ; Myocardial Infarction/pathology ; NF-E2-Related Factor 2/metabolism ; Oils, Volatile/chemistry ; Rats, Wistar ; Saudi Arabia ; Terpenes/chemistry ; Terpenes/therapeutic use
Czasopismo naukowe
Tytuł :
Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase IIβ Interactions.
Autorzy :
Jirkovská A; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Karabanovich G; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Kubeš J; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Skalická V; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Melnikova I; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Korábečný J; Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 50005 Hradec Králové, Czech Republic.; Faculty of Military Health Sciences, University of Defence, Třebešská 1575, 50005 Hradec Králové, Czech Republic.
Kučera T; Faculty of Military Health Sciences, University of Defence, Třebešská 1575, 50005 Hradec Králové, Czech Republic.
Jirkovský E; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Nováková L; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Bavlovič Piskáčková H; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Škoda J; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Štěrba M; Department of Pharmacology, Faculty of Medicine in Hradec Králové, Charles University, Šimkova 870, 50003 Hradec Králové, Czech Republic.
Austin CA; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Šimůnek T; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Roh J; Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Apr 08; Vol. 64 (7), pp. 3997-4019. Date of Electronic Publication: 2021 Mar 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cardiotonic Agents/*therapeutic use
Cardiotoxicity/*drug therapy
Piperazines/*therapeutic use
Topoisomerase II Inhibitors/*therapeutic use
Animals ; Animals, Newborn ; Cardiotonic Agents/chemical synthesis ; Cardiotonic Agents/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; DNA Topoisomerases, Type II/metabolism ; Daunorubicin/toxicity ; Humans ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Myocytes, Cardiac/drug effects ; Piperazines/chemical synthesis ; Piperazines/metabolism ; Protein Binding ; Rats, Wistar ; Saccharomyces cerevisiae/chemistry ; Saccharomyces cerevisiae Proteins/metabolism ; Structure-Activity Relationship ; Topoisomerase II Inhibitors/chemical synthesis ; Topoisomerase II Inhibitors/metabolism
Czasopismo naukowe
Tytuł :
Cardioprotective action of chia (Salvia hispanica L.) in ovariectomized rats fed a high fat diet.
Autorzy :
Mishima MDV; Department of Nutrition and Health. Universidade Federal de Viçosa, Av. Purdue, s/n, Campus Universitário, Viçosa, MG Zip Code: 36.570-900, Brazil. .
Ladeira LCM
da Silva BP
Toledo RCL
de Oliveira TV
Costa NMB
Martino HSD
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Źródło :
Food & function [Food Funct] 2021 Apr 07; Vol. 12 (7), pp. 3069-3082. Date of Electronic Publication: 2021 Mar 15.
Typ publikacji :
Journal Article
MeSH Terms :
Salvia*
Cardiotonic Agents/*therapeutic use
Cardiovascular Diseases/*prevention & control
Plant Extracts/*therapeutic use
Animals ; Cardiotonic Agents/administration & dosage ; Cardiotonic Agents/pharmacology ; Diet, High-Fat ; Disease Models, Animal ; Female ; Obesity ; Ovariectomy ; Plant Extracts/administration & dosage ; Plant Extracts/pharmacology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Kuanxiong aerosol inhibits apoptosis and attenuates isoproterenol-induced myocardial injury through the mitogen-activated protein kinase pathway.
Autorzy :
Lu Y; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Yang M; The Third People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Peng M; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Xie L; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Shen A; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Lin S; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Huang B; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China.
Chu J; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China. Electronic address: .
Peng J; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Chen Keji Academic Thought Inheritance Studio, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China; Fujian Key Laboratory of Integrative Medicine on Geriatrics, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, 350122, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Apr 06; Vol. 269, pp. 113757. Date of Electronic Publication: 2020 Dec 25.
Typ publikacji :
Journal Article
MeSH Terms :
Aerosols/*pharmacology
Apoptosis/*drug effects
Cardiotonic Agents/*pharmacology
Drugs, Chinese Herbal/*pharmacology
MAP Kinase Signaling System/*drug effects
Myocardial Infarction/*drug therapy
Aerosols/chemistry ; Aerosols/therapeutic use ; Animals ; Cardiotonic Agents/chemistry ; Cardiotonic Agents/therapeutic use ; Caspase 3/genetics ; Down-Regulation/drug effects ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/therapeutic use ; Electrocardiography/drug effects ; Gene Expression Regulation/drug effects ; Isoproterenol/toxicity ; Male ; Myocardial Infarction/chemically induced ; Myocardium/metabolism ; Myocardium/pathology ; Proto-Oncogene Proteins c-bcl-2/genetics ; Rats, Inbred WKY ; Transcriptome/drug effects ; Up-Regulation/drug effects ; bcl-2-Associated X Protein/genetics
Czasopismo naukowe
Tytuł :
Allyl Methyl Sulfide Preserved Pressure Overload-Induced Heart Failure Via Modulation of Mitochondrial Function.
Autorzy :
Mohammed SA; Non-Communicable Diseases Group, Translational Health Science and Technology Institute (THSTI), Faridabad, 121001, India. Electronic address: .
Paramesha B; Non-Communicable Diseases Group, Translational Health Science and Technology Institute (THSTI), Faridabad, 121001, India. Electronic address: .
Meghwani H; APCER Life Sciences, US-PVG Department, New Delhi, India. Electronic address: .
Kumar Reddy MP; Cardio-Respiratory Division, Defence Institute of Physiology and Allied Sciences (DIPAS), Defense Research and Development Organization (DRDO), Timarpur, Delhi, India. Electronic address: .
Arava SK; Department of Pathology, All India Institute of Medical Sciences, New Delhi, 110029, India. Electronic address: .
Banerjee SK; Non-Communicable Diseases Group, Translational Health Science and Technology Institute (THSTI), Faridabad, 121001, India; Department of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, 781101, India. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jun; Vol. 138, pp. 111316. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article
MeSH Terms :
Allyl Compounds/*therapeutic use
Cardiotonic Agents/*therapeutic use
Heart Failure/*drug therapy
Mitochondria, Heart/*drug effects
Sulfides/*therapeutic use
Allyl Compounds/pharmacology ; Animals ; Aorta, Thoracic/diagnostic imaging ; Aorta, Thoracic/drug effects ; Aorta, Thoracic/physiopathology ; Cardiomegaly/diagnostic imaging ; Cardiomegaly/drug therapy ; Cardiomegaly/physiopathology ; Cardiotonic Agents/pharmacology ; Cell Line ; Heart Failure/diagnostic imaging ; Heart Failure/physiopathology ; Male ; Mitochondria, Heart/physiology ; Rats ; Rats, Sprague-Dawley ; Stroke Volume/drug effects ; Stroke Volume/physiology ; Sulfides/pharmacology
Czasopismo naukowe
Tytuł :
Pinocembrin inhibited cardiomyocyte pyroptosis against doxorubicin-induced cardiac dysfunction via regulating Nrf2/Sirt3 signaling pathway.
Autorzy :
Gu J; Department of Cardiovascular Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Huang H; Department of Cardiology, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Liu C; Department of Cardiovascular Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Jiang B; Department of Cardiovascular Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Li M; Department of Cardiovascular Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Liu L; Department of Cardiovascular Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
Zhang S; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan 750004, China. Electronic address: .
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Źródło :
International immunopharmacology [Int Immunopharmacol] 2021 Jun; Vol. 95, pp. 107533. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiotonic Agents/*therapeutic use
Cardiotoxicity/*drug therapy
Flavanones/*therapeutic use
Myocytes, Cardiac/*drug effects
NF-E2-Related Factor 2/*metabolism
Sirtuin 3/*metabolism
Animals ; Antibiotics, Antineoplastic ; Cardiotonic Agents/pharmacology ; Cardiotoxicity/metabolism ; Cell Line ; Doxorubicin ; Flavanones/pharmacology ; Male ; Mice, Inbred C57BL ; Myocardium/metabolism ; Myocardium/pathology ; Myocytes, Cardiac/metabolism ; NF-E2-Related Factor 2/genetics ; Pyroptosis/drug effects ; Rats ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Cardiopreventive capacity of a novel (E)-N'-(1-(7-methoxy-2-oxo-2H-chromen-3-yl) ethylidene)-4-methylbenzenesulfonohydrazide against isoproterenol-induced myocardial infarction by moderating biochemical, oxidative stress, and histological parameters.
Autorzy :
Khdhiri E; Laboratoire de Chimie Appliquée 'Hétérocycles Corps Gras & Polymères', Faculté des Sciences, Université de Sfax, Sfax, Tunisie.
Mnafgui K; Laboratory of Animal Physiology, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Ncir M; Laboratory of Animal Physiology, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Feriani A; Research Unit of Macromolecular Biochemistry and Genetics, Faculty of Sciences of Gafsa, Gafsa, Tunisia.
Ghazouani L; Research Unit of Macromolecular Biochemistry and Genetics, Faculty of Sciences of Gafsa, Gafsa, Tunisia.
Hajji R; Service de Médecine Interne, Hôpital de Sidi Bouzid, Sidi Bouzid 9100, Tunisie, Université de Sousse, Faculté de Médecine de Sousse, Sousse 4200, Tunisie.
Jallouli D; Biochemistry Laboratory, CHU Habib Bourguiba of Sfax, Sfax, Tunisia.
Abid M; Chemistry Department, College of Science and Arts, Jouf University, Al Jawf, Saudi Arabia.
Jamoussi K; Biochemistry Laboratory, CHU Habib Bourguiba of Sfax, Sfax, Tunisia.
Allouche N; Laboratory of Organic Chemistry LR17ES08 (Natural Substances Team), Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Ammar H; Laboratoire de Chimie Appliquée 'Hétérocycles Corps Gras & Polymères', Faculté des Sciences, Université de Sfax, Sfax, Tunisie.
Abid S; Chemistry Department, College of Science and Arts, Jouf University, Al Jawf, Saudi Arabia.
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Źródło :
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2021 Jun; Vol. 35 (6), pp. e22747. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article
MeSH Terms :
Myocardial Infarction*/chemically induced
Myocardial Infarction*/metabolism
Myocardial Infarction*/pathology
Myocardial Infarction*/prevention & control
Myocardium*/metabolism
Myocardium*/pathology
Benzenesulfonates/*pharmacology
Cardiotonic Agents/*pharmacology
Isoproterenol/*adverse effects
Oxidative Stress/*drug effects
Animals ; Benzenesulfonates/chemistry ; Cardiotonic Agents/chemistry ; Isoproterenol/pharmacology ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Impact of Hepatic CYP3A4 Ontogeny Functions on Drug-Drug Interaction Risk in Pediatric Physiologically-Based Pharmacokinetic/Pharmacodynamic Modeling: Critical Literature Review and Ivabradine Case Study.
Autorzy :
Lang J; Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Vincent L; Centre de Pharmacocinétique et Métabolisme, Technologie Servier, Orléans, France.
Chenel M; Clinical Pharmacokinetics and Pharmacometrics, Institut de Recherches Internationales Servier, Suresnes, France.
Ogungbenro K; Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Galetin A; Centre for Applied Pharmacokinetic Research, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Jun; Vol. 109 (6), pp. 1618-1630. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Interactions*
Cardiotonic Agents/*pharmacokinetics
Cytochrome P-450 CYP3A/*genetics
Ivabradine/*pharmacokinetics
Liver/*enzymology
Adolescent ; Antifungal Agents/adverse effects ; Antifungal Agents/pharmacokinetics ; Cardiotonic Agents/adverse effects ; Child ; Child, Preschool ; Cytochrome P-450 CYP3A Inducers ; Cytochrome P-450 CYP3A Inhibitors/pharmacokinetics ; Drug-Related Side Effects and Adverse Reactions/epidemiology ; Drug-Related Side Effects and Adverse Reactions/genetics ; Humans ; Infant ; Infant, Newborn ; Ivabradine/adverse effects ; Ketoconazole/adverse effects ; Ketoconazole/pharmacokinetics ; Pediatrics
Czasopismo naukowe

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