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Tytuł :
Erratum for Rivera-Hernandez et al., "An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model".
Autorzy :
Rivera-Hernandez T; Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, QLD, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
Carnathan DG; Emory Vaccine Center, Emory University, Atlanta, Georgia, USA.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Jones S; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
Cork AJ; Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, QLD, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
Davies MR; Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, QLD, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.; Peter Doherty Institute, University of Melbourne, Parkville, VIC, Australia.
Moyle PM; Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, QLD, Australia.; School of Pharmacy, The University of Queensland, St. Lucia, QLD, Australia.
Toth I; Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, QLD, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
Batzloff MR; Institute for Glycomics, Griffith University, Gold Coast, QLD, Australia.
McCarthy J; Australian Infectious Diseases Research Centre, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Nizet V; Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California-San Diego, La Jolla, California, USA.
Goldblatt D; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
Silvestri G; Emory Vaccine Center, Emory University, Atlanta, Georgia, USA.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Walker MJ; Australian Infectious Diseases Research Centre, The University of Queensland, St. Lucia, QLD, Australia .; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, QLD, Australia.
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Źródło :
MBio [mBio] 2020 Dec 01; Vol. 11 (6). Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Published Erratum
Czasopismo naukowe
Tytuł :
Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations
Autorzy :
Martin, Jacob T.Aff1, Aff2
Cottrell, Christopher A.Aff2, Aff3
Antanasijevic, AleksandarAff2, Aff3
Carnathan, Diane G.Aff2, Aff4, Aff5
Cossette, Benjamin J.Aff1, Aff2
Enemuo, Chiamaka A.Aff4, Aff5
Gebru, Etse H.Aff4, Aff5
Choe, YuryAff4, Aff5
Viviano, FedericoAff4, Aff5
Fischinger, StephanieAff6, Aff7
Tokatlian, TalarAff1, Aff2
Cirelli, Kimberly M.Aff2, Aff8
Ueda, GeorgeAff9, Aff10
Copps, Jeffrey
Schiffner, TorbenAff2, Aff11
Menis, SergeyAff2, Aff11
Alter, Galit
Schief, William R.Aff2, Aff6, Aff11
Crotty, ShaneAff2, Aff8, Aff12
King, Neil P.Aff9, Aff10
Baker, DavidAff9, Aff10, Aff13
Silvestri, GuidoAff2, Aff4, Aff5
Ward, Andrew B.Aff2, Aff3, Aff11
Irvine, Darrell J.Aff1, Aff2, Aff6, Aff13, Aff14, Aff15
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Źródło :
npj Vaccines. 5(1)
Czasopismo naukowe
Tytuł :
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Autorzy :
Cottrell CA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, California, United States of America.
van Schooten J; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Bowman CA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Yuan M; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Oyen D; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Shin M; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Morpurgo R; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
van der Woude P; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
van Breemen M; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Torres JL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Patel R; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Gross J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Sewall LM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Copps J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Ozorowski G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, California, United States of America.
Nogal B; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, California, United States of America.
Sok D; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, California, United States of America.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.
Rakasz EG; Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin, United States of America.
Labranche C; Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America.
Vigdorovich V; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America.
Christley S; Department of Population and Data Sciences, UT Southwestern Medical Center, Dallas, Texas, United States of America.
Carnathan DG; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, California, United States of America.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
Sather DN; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, United States of America.
Montefiori D; Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America.; Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America.
Silvestri G; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, California, United States of America.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
Burton DR; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, California, United States of America.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America.
Moore JP; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America.
Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, California, United States of America.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America.
Sanders RW; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America.
Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, California, United States of America.; Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, California, United States of America.
van Gils MJ; Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
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Źródło :
PLoS pathogens [PLoS Pathog] 2020 Aug 31; Vol. 16 (8), pp. e1008753. Date of Electronic Publication: 2020 Aug 31 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Epitope Mapping*
AIDS Vaccines/*immunology
Epitopes/*immunology
HIV Antibodies/*immunology
HIV Envelope Protein gp120/*immunology
HIV Envelope Protein gp41/*immunology
HIV-1/*immunology
AIDS Vaccines/genetics ; Animals ; Antibodies, Monoclonal, Murine-Derived/immunology ; Epitopes/genetics ; HIV Antibodies/genetics ; HIV Envelope Protein gp41/genetics ; HIV-1/genetics ; Macaca mulatta ; Protein Multimerization/genetics ; Protein Multimerization/immunology
Czasopismo naukowe
Tytuł :
Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers.
Autorzy :
Carnathan DG; Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States.; Scripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.; Emory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, United States.
Kaushik K; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA, United States.
Ellebedy AH; Emory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, United States.; Department of Microbiology and Immunology, School of Medicine, Emory University, Atlanta, GA, United States.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, United States.
Enemuo CA; Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Gebru EH; Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Dhadvai P; Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Rasheed MAU; Emory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, United States.; Department of Microbiology and Immunology, School of Medicine, Emory University, Atlanta, GA, United States.
Pauthner MG; Scripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, United States.
Ozorowski G; Scripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States.
Ahmed R; Emory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, United States.; Department of Microbiology and Immunology, School of Medicine, Emory University, Atlanta, GA, United States.
Burton DR; Scripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, United States.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States.
Ward AB; Scripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, United States.
Silvestri G; Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States.; Scripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.; Emory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, United States.
Crotty S; Scripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA, United States.; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California, San Diego, La Jolla, CA, United States.
Locci M; Scripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.; Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA, United States.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Jun 16; Vol. 11, pp. 1213. Date of Electronic Publication: 2020 Jun 16 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8 cells.
Autorzy :
McBrien JB; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Mavigner M; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Franchitti L; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Smith SA; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
White E; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Tharp GK; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Walum H; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Busman-Sahay K; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.
Aguilera-Sandoval CR; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Thayer WO; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Spagnuolo RA; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kovarova M; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wahl A; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Cervasi B; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Margolis DM; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; University of North Carolina HIV Cure Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Vanderford TH; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Carnathan DG; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Paiardini M; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Lee JH; NantKwest, Culver City, CA, USA.
Safrit JT; NantKwest, Culver City, CA, USA.
Bosinger SE; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Estes JD; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Derdeyn CA; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Garcia JV; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kulpa DA; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Chahroudi A; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.; Emory + Children's Center for Childhood Infections and Vaccines, Atlanta, GA, USA.
Silvestri G; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA. .; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA. .
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Źródło :
Nature [Nature] 2020 Feb; Vol. 578 (7796), pp. E21.
Typ publikacji :
Published Erratum
Tytuł :
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8 cells.
Autorzy :
McBrien JB; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Mavigner M; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Franchitti L; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Smith SA; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
White E; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Tharp GK; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Walum H; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Busman-Sahay K; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.
Aguilera-Sandoval CR; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Thayer WO; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Spagnuolo RA; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kovarova M; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Wahl A; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Cervasi B; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Margolis DM; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; University of North Carolina HIV Cure Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Vanderford TH; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Carnathan DG; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.
Paiardini M; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Lifson JD; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Lee JH; NantKwest, Culver City, CA, USA.
Safrit JT; NantKwest, Culver City, CA, USA.
Bosinger SE; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Estes JD; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Derdeyn CA; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Garcia JV; International Center for the Advancement of Translational Science, Division of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kulpa DA; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Chahroudi A; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.; Emory + Children's Center for Childhood Infections and Vaccines, Atlanta, GA, USA.
Silvestri G; Emory Vaccine Center and Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA. .; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA. .
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Źródło :
Nature [Nature] 2020 Feb; Vol. 578 (7793), pp. 154-159. Date of Electronic Publication: 2020 Jan 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Replication*/immunology
CD8-Positive T-Lymphocytes/*immunology
Interleukin-15/*agonists
Simian Immunodeficiency Virus/*physiology
Animals ; CD4-Positive T-Lymphocytes/virology ; HIV Infections/immunology ; HIV Infections/virology ; Humans ; Interleukin-15/immunology ; Lymphocyte Depletion ; Macaca mulatta ; Mice ; Simian Acquired Immunodeficiency Syndrome/immunology ; Simian Acquired Immunodeficiency Syndrome/virology ; Virus Latency
Czasopismo naukowe
Tytuł :
Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance.
Autorzy :
Cirelli KM
Carnathan DG
Nogal B
Martin JT
Rodriguez OL
Upadhyay AA
Enemuo CA
Gebru EH
Choe Y
Viviano F
Nakao C
Pauthner MG
Reiss S
Cottrell CA
Smith ML
Bastidas R
Gibson W
Wolabaugh AN
Melo MB
Cossette B
Kumar V
Patel NB
Tokatlian T
Menis S
Kulp DW
Burton DR
Murrell B
Schief WR
Bosinger SE
Ward AB
Watson CT
Silvestri G
Irvine DJ
Crotty S
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Źródło :
Cell [Cell] 2020 Jan 09; Vol. 180 (1), pp. 206.
Typ publikacji :
Published Erratum
Tytuł :
Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization.
Autorzy :
Havenar-Daughton C; Division of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA.
Carnathan DG; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Boopathy AV; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Upadhyay AA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Murrell B; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm 17177, Sweden.
Reiss SM; Division of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA.
Enemuo CA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Gebru EH; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Choe Y; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Dhadvai P; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Viviano F; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Kaushik K; Division of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA.
Bhiman JN; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02129, USA.
Briney B; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
Burton DR; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02129, USA.
Bosinger SE; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA.
Schief WR; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02129, USA.
Irvine DJ; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02129, USA.
Silvestri G; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA. Electronic address: .
Crotty S; Division of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, San Diego, CA 92103, USA. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2019 Nov 12; Vol. 29 (7), pp. 1756-1766.e8.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Antibody Formation*
Immunization*
Nanoparticles*
B-Lymphocytes/*immunology
CD4-Positive T-Lymphocytes/*immunology
Germinal Center/*immunology
Vaccines/*pharmacology
Animals ; B-Lymphocytes/pathology ; Biopsy, Fine-Needle ; CD4-Positive T-Lymphocytes/pathology ; Germinal Center/pathology ; Humans ; Macaca mulatta ; Male ; Vaccines/immunology
Czasopismo naukowe
Tytuł :
Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance.
Autorzy :
Cirelli KM; Division of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA.
Carnathan DG; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Nogal B; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Martin JT; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Rodriguez OL; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Upadhyay AA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA.
Enemuo CA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Gebru EH; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Choe Y; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Viviano F; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Nakao C; Division of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Pauthner MG; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Reiss S; Division of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA.
Cottrell CA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Smith ML; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Bastidas R; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Gibson W; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Wolabaugh AN; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA.
Melo MB; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Cossette B; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Kumar V; Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA.
Patel NB; Yerkes NHP Genomics Core Laboratory, Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Tokatlian T; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Menis S; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Kulp DW; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Vaccine and Immunotherapy Center, Wistar Institute, Philadelphia, PA 19104, USA.
Burton DR; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA.
Murrell B; Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Schief WR; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA.
Bosinger SE; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Yerkes NHP Genomics Core Laboratory, Yerkes National Primate Research Center, Atlanta, GA 30329, USA.
Ward AB; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Watson CT; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Silvestri G; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Irvine DJ; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA; Departments of Biological Engineering and Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Crotty S; Division of Vaccine Discovery, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID), The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA. Electronic address: .
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Źródło :
Cell [Cell] 2019 May 16; Vol. 177 (5), pp. 1153-1171.e28. Date of Electronic Publication: 2019 May 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunization, Passive*
Antibodies, Neutralizing/*immunology
B-Lymphocytes/*immunology
Germinal Center/*immunology
HIV Antibodies/*immunology
HIV-1/*immunology
T-Lymphocytes, Helper-Inducer/*immunology
Animals ; B-Lymphocytes/pathology ; Female ; Germinal Center/pathology ; Germinal Center/virology ; Macaca mulatta ; Male ; T-Lymphocytes, Helper-Inducer/pathology ; env Gene Products, Human Immunodeficiency Virus/immunology
Czasopismo naukowe
Tytuł :
An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model.
Autorzy :
Rivera-Hernandez T; Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, QLD, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.
Carnathan DG; Emory Vaccine Center, Emory University, Atlanta, Georgia, USA.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Jones S; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
Cork AJ; Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, QLD, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.
Davies MR; Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, QLD, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.; Peter Doherty Institute, University of Melbourne, Parkville, VIC, Australia.
Moyle PM; Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, QLD, Australia.; School of Pharmacy, The University of Queensland, St Lucia, QLD, Australia.
Toth I; Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, QLD, Australia.; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.
Batzloff MR; Institute for Glycomics, Griffith University, Gold Coast, QLD, Australia.
McCarthy J; Australian Infectious Diseases Research Centre, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Nizet V; Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California-San Diego, La Jolla, California, USA.
Goldblatt D; Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.
Silvestri G; Emory Vaccine Center, Emory University, Atlanta, Georgia, USA.; Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.
Walker MJ; Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, QLD, Australia .; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia.
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Źródło :
MBio [mBio] 2019 Apr 30; Vol. 10 (2). Date of Electronic Publication: 2019 Apr 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Pharyngitis/*prevention & control
Streptococcal Infections/*prevention & control
Streptococcal Vaccines/*immunology
Streptococcus pyogenes/*immunology
Tonsillitis/*prevention & control
Animals ; Antibodies, Bacterial/blood ; Disease Models, Animal ; Female ; Macaca mulatta ; Male ; Streptococcal Vaccines/administration & dosage ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Susceptibility to SIV Infection After Adenoviral Vaccination in a Low Dose Rhesus Macaque Challenge Model.
Autorzy :
Brody IB; Department of Microbiology; Perelman School of Medicine, University of Pennsylvania; Philadelphia, Pennsylvania.
Calcedo R; Gene Therapy Program; Department of Medicine, Perelman School of Medicine, University of Pennsylvania; Philadelphia, Pennsylvania.
Connell MJ; The Children's Hospital of Philadelphia Research Institute; Philadelphia, Pennsylvania.
Carnathan DG; Emory Vaccine Center; Yerkes National Primate Research Center, Emory University; Atlanta, Georgia.
Nason M; Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health; Bethesda, Maryland.
Lawson BO; Emory Vaccine Center; Yerkes National Primate Research Center, Emory University; Atlanta, Georgia.
Nega MT; Emory Vaccine Center; Yerkes National Primate Research Center, Emory University; Atlanta, Georgia.
Boyd S; Gene Therapy Program; Department of Medicine, Perelman School of Medicine, University of Pennsylvania; Philadelphia, Pennsylvania.
Qin Q; Gene Therapy Program; Department of Medicine, Perelman School of Medicine, University of Pennsylvania; Philadelphia, Pennsylvania.
Vanderford TH; Emory Vaccine Center; Yerkes National Primate Research Center, Emory University; Atlanta, Georgia.
Wilson JM; University Laboratory Animal Resources; Perelman School of Medicine, University of Pennsylvania; Philadelphia, Pennsylvania.
Wilson JM; Gene Therapy Program; Department of Medicine, Perelman School of Medicine, University of Pennsylvania; Philadelphia, Pennsylvania.
Silvestri G; Emory Vaccine Center; Yerkes National Primate Research Center, Emory University; Atlanta, Georgia.
Betts MR; Department of Microbiology; Perelman School of Medicine, University of Pennsylvania; Philadelphia, Pennsylvania.
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Źródło :
Pathogens & immunity [Pathog Immun] 2019 Jan 29; Vol. 4 (1), pp. 1-20. Date of Electronic Publication: 2019 Jan 29 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Antibody-Mediated CD4 Depletion Induces Homeostatic CD4 T Cell Proliferation without Detectable Virus Reactivation in Antiretroviral Therapy-Treated Simian Immunodeficiency Virus-Infected Macaques.
Autorzy :
Kumar, Nitasha A.
McBrien, Julia B.
Carnathan, Diane G.
Mavigner, Maud
Mattingly, Cameron
White, Erick R.
Viviano, Federico
Bosinger, Steve E.
Chahroudi, Ann
Silvestri, Guido
Paiardini, Mirko
Vanderford, Thomas H.
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Źródło :
Journal of Virology. Nov2018, Vol. 92 Issue 22, p1-13. 13p.
Czasopismo naukowe
Tytuł :
Short-Term Pegylated Interferon α2a Treatment Does Not Significantly Reduce the Viral Reservoir of Simian Immunodeficiency Virus-Infected, Antiretroviral Therapy-Treated Rhesus Macaques.
Autorzy :
Palesch, David
Bosinger, Steven E.
Mavigner, Maud
Billingsley, James M.
Mattingly, Cameron
Carnathan, Diane G.
Paiardini, Mirko
Chahroudi, Ann
Vanderford, Thomas H.
Silvestri, Guido
Pokaż więcej
Źródło :
Journal of Virology. Jul2018, Vol. 92 Issue 14, p1-18. 18p.
Czasopismo naukowe
Tytuł :
Intragastric Administration of Lactobacillus plantarum and 2,2=-Dithiodipyridine-Inactivated Simian Immunodeficiency Virus (SIV) Does Not Protect Indian Rhesus Macaques from Intrarectal SIV Challenge or Reduce Virus Replication after Transmission.
Autorzy :
Carnathan, Diane G.
Mackel, Joseph J.
Sweat, Shelby L.
Enemuo, Chiamaka A.
Gebru, Etse H.
Dhadvai, Pallavi
Gangadhara, Sailaja
Hicks, Sakeenah
Vanderford, Thomas H.
Amara, Rama R.
Esparza, José
Wei Lu
Andrieu, Jean-Marie
Silvestri, Guido
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Źródło :
Journal of Virology. May2018, Vol. 92 Issue 10, p1-11. 11p.
Czasopismo naukowe
Tytuł :
Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.
Autorzy :
Pauthner M; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
Havenar-Daughton C; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.
Sok D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; International AIDS Vaccine Initiative, New York, NY 10004, USA.
Nkolola JP; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Bastidas R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
Boopathy AV; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Carnathan DG; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Chandrashekar A; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Cirelli KM; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.
Cottrell CA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Eroshkin AM; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Bioinformatics Core, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Guenaga J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
Kaushik K; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.
Kulp DW; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
Liu J; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
McCoy LE; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Division of Infection & Immunity, University College London, London WC1E 6BT, UK.
Oom AL; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA; University of California, San Diego, La Jolla, CA 92093, USA.
Ozorowski G; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Post KW; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Bioinformatics Core, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
Sharma SK; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
Steichen JM; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
de Taeye SW; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands.
Tokatlian T; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Torrents de la Peña A; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands.
Butera ST; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
LaBranche CC; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Silvestri G; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
Wilson IA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Irvine DJ; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Departments of Biological Engineering and Materials Science & Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Sanders RW; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10065, USA; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, the Netherlands.
Schief WR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA.
Ward AB; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Wyatt RT; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA.
Barouch DH; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA.
Crotty S; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA 92037, USA. Electronic address: .
Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; IAVI Neutralizing Antibody Center and the Collaboration for AIDS Vaccine Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, MA 02139, USA. Electronic address: .
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Źródło :
Immunity [Immunity] 2017 Jun 20; Vol. 46 (6), pp. 1073-1088.e6.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
AIDS Vaccines/*immunology
Antibodies, Neutralizing/*therapeutic use
Germinal Center/*immunology
HIV Antibodies/*therapeutic use
HIV Infections/*therapy
HIV-1/*immunology
Animals ; Cells, Cultured ; Epitopes, B-Lymphocyte/chemistry ; Epitopes, B-Lymphocyte/immunology ; Germinal Center/virology ; HIV Infections/immunology ; Humans ; Immunization ; Injections, Subcutaneous ; Primates ; Protein Multimerization ; env Gene Products, Human Immunodeficiency Virus/chemistry ; env Gene Products, Human Immunodeficiency Virus/immunology
Czasopismo naukowe
Tytuł :
Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches
Autorzy :
Pauthner, Matthias
Havenar-Daughton, Colin
Sok, Devin
Nkolola, Joseph P.
Bastidas, Raiza
Boopathy, Archana V.
Carnathan, Diane G.
Chandrashekar, Abishek
Cirelli, Kimberly M.
Cottrell, Christopher A.
Eroshkin, Alexey M.
Guenaga, Javier
Kaushik, Kirti
Kulp, Daniel W.
Liu, Jinyan
McCoy, Laura E.
Oom, Aaron L.
Ozorowski, Gabriel
Post, Kai W.
Sharma, Shailendra K.
Steichen, Jon M.
de Taeye, Steven W.
Tokatlian, Talar
Torrents de la Peña, Alba
Butera, Salvatore T.
LaBranche, Celia C.
Montefiori, David C.
Silvestri, Guido
Wilson, Ian A.
Irvine, Darrell J.
Sanders, Rogier W.
Schief, William R.
Ward, Andrew B.
Wyatt, Richard T.
Barouch, Dan H.
Crotty, Shane
Burton, Dennis R.
Pokaż więcej
Temat :
HIV vaccine
nonhuman primates
rhesus macaques
BG505
SOSIP
NFL
GC B cells
protein design
Tfh cells
germinal centers
Źródło :
Pauthner, M., C. Havenar-Daughton, D. Sok, J. P. Nkolola, R. Bastidas, A. V. Boopathy, D. G. Carnathan, et al. 2017. “Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.” Immunity 46 (6): 1073-1088.e6. doi:10.1016/j.immuni.2017.05.007. http://dx.doi.org/10.1016/j.immuni.2017.05.007.
Relacje :
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483234/pdf/; Immunity
Dostęp URL :
http://nrs.harvard.edu/urn-3:HUL.InstRepos:33490817
Czasopismo naukowe

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