Temat: "Carrageenan" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Anti-Inflammatory Effect of Izalpinin Derived from Chromolaena leivensis : λ-Carrageenan-Induced Paw Edema and In Silico Model.
Autorzy:: Mancipe JC; Facultad de Ciencias Agropecuarias, Universidad de la Salle, Bogotá 110141, Colombia.
Vargas-Pinto P; Facultad de Ciencias Agropecuarias, Universidad de la Salle, Bogotá 110141, Colombia.
Rodríguez OE; Facultad de Ingeniería, Universidad del Bosque, Bogotá 110121, Colombia.; Escuela de Medicina, Fundación Universitaria Juan N. Corpas, Bogotá 110311, Colombia.
Borrego-Muñoz P; Facultad de Ingeniería, Universidad del Bosque, Bogotá 110121, Colombia.
Castellanos Londoño I; Facultad de Ciencias Agropecuarias, Universidad de la Salle, Bogotá 110141, Colombia.
Ramírez D; Departamento de Farmacología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción 4030000, Chile.
Piñeros LG; Facultad de Ingeniería, Universidad del Bosque, Bogotá 110121, Colombia.
Mejía MC; Facultad de Ingeniería, Universidad del Bosque, Bogotá 110121, Colombia.
Pombo LM; Facultad de Ingeniería, Universidad del Bosque, Bogotá 110121, Colombia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Apr 26; Vol. 28 (9). Date of Electronic Publication: 2023 Apr 26.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents*/therapeutic use
Chromolaena*
Rats ; Animals ; Carrageenan/adverse effects ; Molecular Docking Simulation ; Plant Extracts/therapeutic use ; Edema/chemically induced ; Edema/drug therapy ; Edema/metabolism

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Skocz do pozycji: 2.

Tytuł:: Phenylbenzohydrazides Obtained from Isatoic Anhydride Present Anti-Inflammatory Activity In Vivo and In Vitro.
Autorzy:: Paiva JPB; Laboratório de Farmacologia da Dor e da Inflamação, Programa de Pesquisa em Descoberta de Fármacos, Instituto de Ciências Biomédicas, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Cordeiro MS; Laboratório de Farmacologia da Dor e da Inflamação, Programa de Pesquisa em Descoberta de Fármacos, Instituto de Ciências Biomédicas, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
França PRC; Laboratório de Farmacologia da Dor e da Inflamação, Programa de Pesquisa em Descoberta de Fármacos, Instituto de Ciências Biomédicas, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Branco LOP; Laboratório de Catálise e Síntese de Substâncias Bioativas, CM UFRJ-Macaé, Instituto Multidisciplinar de Química, Universidade Federal do Rio de Janeiro, 27971-525 Macaé, Brazil.
Santos IS; Laboratório de Catálise e Síntese de Substâncias Bioativas, CM UFRJ-Macaé, Instituto Multidisciplinar de Química, Universidade Federal do Rio de Janeiro, 27971-525 Macaé, Brazil.
Reis NF; Laboratório de Catálise e Síntese de Substâncias Bioativas, CM UFRJ-Macaé, Instituto Multidisciplinar de Química, Universidade Federal do Rio de Janeiro, 27971-525 Macaé, Brazil.
Pimentel PP; Laboratório de Catálise e Síntese de Substâncias Bioativas, CM UFRJ-Macaé, Instituto Multidisciplinar de Química, Universidade Federal do Rio de Janeiro, 27971-525 Macaé, Brazil.
Giorno TBS; Laboratório de Farmacologia da Dor e da Inflamação, Programa de Pesquisa em Descoberta de Fármacos, Instituto de Ciências Biomédicas, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Lima EC; Laboratório de Catálise e Síntese de Substâncias Bioativas, CM UFRJ-Macaé, Instituto Multidisciplinar de Química, Universidade Federal do Rio de Janeiro, 27971-525 Macaé, Brazil.
Fernandes PD; Laboratório de Farmacologia da Dor e da Inflamação, Programa de Pesquisa em Descoberta de Fármacos, Instituto de Ciências Biomédicas, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2022 Dec 19; Vol. 12 (12). Date of Electronic Publication: 2022 Dec 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Nitric Oxide*/metabolism
Anti-Inflammatory Agents*/pharmacology
Anti-Inflammatory Agents*/therapeutic use
Humans ; Carrageenan ; Cytokines/metabolism ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/metabolism

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Skocz do pozycji: 3.

Tytuł:: Evaluation of the in vivo and in vitro anti-inflammatory activity of a new hybrid NSAID tetrahydropyran derivative.
Autorzy:: Gonçalves GM; Laboratório de Farmacologia da Inflamação e Nocicepção, Programa de Pós-Graduação em Ciências Fisiológicas, Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brasil.
de Oliveira JM; Laboratório de Farmacologia da Inflamação e Nocicepção, Programa de Pós-Graduação em Ciências Fisiológicas, Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brasil.
Ferreira da Costa Fernandes T; Departamento de Ciências Naturais, Campus Rio das Ostras, Universidade Federal Fluminense, Rio das Ostras, RJ, Brasil.
Laureano-Melo R; Laboratório de Fisiofarmacologia Comportamental, Centro Universitário de Barra Mansa, Barra Mansa, RJ, Brasil.
da Silva Côrtes W; Laboratório de Farmacologia da Inflamação e Nocicepção, Programa de Pós-Graduação em Ciências Fisiológicas, Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brasil.
Capim SL; Instituto Federal de Educação, Ciência e Tecnologia Baiano, Campus Catu, BA, Brasil.
Araujo de Almeida Vasconcellos ML; Laboratório de Síntese Orgânica Medicinal da Paraíba (LASOM-PB), Departamento de Química, Universidade Federal da Paraíba, Campus I, João Pessoa, PB, Brasil.
Guimarães Marinho B; Laboratório de Farmacologia da Inflamação e Nocicepção, Programa de Pós-Graduação em Ciências Fisiológicas, Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brasil.; Pokaż więcej
Źródło:: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2022 Apr; Vol. 100 (4), pp. 341-351. Date of Electronic Publication: 2022 Jan 24.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents*/pharmacology
Anti-Inflammatory Agents*/therapeutic use
Anti-Inflammatory Agents, Non-Steroidal*/therapeutic use
Animals ; Carrageenan/adverse effects ; Edema/chemically induced ; Edema/drug therapy ; Male ; Mice ; Nitric Oxide/metabolism ; Tumor Necrosis Factor-alpha

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Skocz do pozycji: 4.

Tytuł:: Therapeutic Uses of Red Macroalgae.
Autorzy:: Ismail MM; National Institute of Oceanography and Fisheries, NIOF, Alexandria 21556, Egypt.
Alotaibi BS; Pharmaceutical Sciences Department, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
El-Sheekh MM; Botany Department, Faculty of Science, Tanta University, Tanta 31527, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Sep 25; Vol. 25 (19). Date of Electronic Publication: 2020 Sep 25.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Anti-Inflammatory Agents*/chemistry
Anti-Inflammatory Agents*/therapeutic use
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/therapeutic use
Carrageenan*/chemistry
Carrageenan*/therapeutic use
Cholinesterase Inhibitors*/chemistry
Cholinesterase Inhibitors*/therapeutic use
Galactans*/chemistry
Galactans*/therapeutic use
Rhodophyta/*chemistry
Seaweed/*chemistry
Animals ; Humans

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Skocz do pozycji: 5.

Tytuł:: Anti-Inflammatory Activities of the Ethanol Extract of Prasiola japonica , an Edible Freshwater Green Algae, and Its Various Solvent Fractions in LPS-Induced Macrophages and Carrageenan-Induced Paw Edema via the AP-1 Pathway.
Autorzy:: Rahmawati L; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Park SH; Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Korea.
Kim DS; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Lee HP; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Aziz N; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Lee CY; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Kim SA; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.
Jang SG; Research and Business Foundation, Sungkyunkwan University, Suwon 16419, Korea.
Kim DS; Research and Business Foundation, Sungkyunkwan University, Suwon 16419, Korea.
Cho JY; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon 16419, Korea.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Dec 29; Vol. 27 (1). Date of Electronic Publication: 2021 Dec 29.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Biological Products/*pharmacology
Chlorophyta/*chemistry
Edema/*drug therapy
Edema/*etiology
Signal Transduction/*drug effects
Transcription Factor AP-1/*metabolism
Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/isolation & purification ; Biological Products/chemistry ; Biological Products/isolation & purification ; Biomarkers ; Carrageenan/adverse effects ; Chemical Fractionation/methods ; Disease Management ; Disease Models, Animal ; Drug Evaluation, Preclinical ; Edema/metabolism ; Edema/pathology ; Gene Expression Regulation/drug effects ; Lipopolysaccharides/adverse effects ; Macrophages/drug effects ; Macrophages/immunology ; Macrophages/metabolism ; Mice ; Nitric Oxide/metabolism ; RAW 264.7 Cells ; Solvents

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Skocz do pozycji: 6.

Tytuł:: Antinociceptive and anti-inflammatory effects of hydrazone derivatives and their possible mechanism of action in mice.
Autorzy:: Medeiros MAMB; Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.; Pós-Graduação em Biotecnologia, Universidade Estadual de Feira de Santana, Feira de Santana, Bahia, Brasil.
Gama E Silva M; Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.; Pós-Graduação em Biotecnologia-Rede Nordeste de Biotecnologia (RENORBIO), Universidade Federal Rural de Pernambuco, Recife, Pernambuco, Brasil.
de Menezes Barbosa J; Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.; Pós-Graduação em Biotecnologia-Rede Nordeste de Biotecnologia (RENORBIO), Universidade Federal Rural de Pernambuco, Recife, Pernambuco, Brasil.
Martins de Lavor É; Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.; Pós-Graduação em Biotecnologia, Universidade Estadual de Feira de Santana, Feira de Santana, Bahia, Brasil.
Ribeiro TF; Pós-Graduação em Biotecnologia-Rede Nordeste de Biotecnologia (RENORBIO), Universidade Federal Rural de Pernambuco, Recife, Pernambuco, Brasil.
Macedo CAF; Pós-Graduação em Biotecnologia, Universidade Estadual de Feira de Santana, Feira de Santana, Bahia, Brasil.
de Souza Duarte-Filho LAM; Pós Graduação em Biociências, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.
Feitosa TA; Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.; Pós Graduação em Biociências, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.
de Jesus Silva J; Colegiado de Farmácia, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.
Fokoue HH; Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brasil.
Araújo CRM; Colegiado de Farmácia, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.
de Assis Gonsalves A; Colegiado de Farmácia, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.
Augusto de Araújo Ribeiro L; Pós Graduação em Biociências, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.; Colegiado de Farmácia, Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.
Almeida JRGDS; Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco, Petrolina, Pernambuco, Brasil.; Pós-Graduação em Biotecnologia, Universidade Estadual de Feira de Santana, Feira de Santana, Bahia, Brasil.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2021 Nov 24; Vol. 16 (11), pp. e0258094. Date of Electronic Publication: 2021 Nov 24 (Print Publication: 2021).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Analgesics/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Hydrazones/*pharmacology
Analgesics/chemistry ; Analgesics/therapeutic use ; Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/therapeutic use ; Artemia/drug effects ; Carrageenan ; Edema/chemically induced ; Edema/drug therapy ; Hydrazones/chemical synthesis ; Hydrazones/chemistry ; Hydrazones/therapeutic use ; Male ; Mice ; Molecular Docking Simulation ; Toxicity Tests

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Skocz do pozycji: 7.

Tytuł:: Antioxidant and Anti-Inflammatory Effects of Peganum harmala Extracts: An In Vitro and In Vivo Study.
Autorzy:: Abbas MW; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
Hussain M; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
Qamar M; Institute of Food Science and Nutrition, Bahauddin Zakariya University, Multan 60800, Pakistan.
Ali S; Department of Biotechnology, University of Management and Technology, Sialkot 51041, Pakistan.
Shafiq Z; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan.
Wilairatana P; Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Mubarak MS; Department of Chemistry, The University of Jordan, Amman 11942, Jordan.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 08; Vol. 26 (19). Date of Electronic Publication: 2021 Oct 08.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*administration & dosage
Antioxidants/*administration & dosage
Carrageenan/*adverse effects
Edema/*drug therapy
Peganum/*chemistry
Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Disease Models, Animal ; Edema/chemically induced ; Indomethacin/pharmacology ; Lethal Dose 50 ; Mice ; Plant Extracts/chemistry ; Quercetin/pharmacology ; Rats ; Toxicity Tests, Acute ; Toxicity Tests, Subacute

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Skocz do pozycji: 8.

Tytuł:: Oral and Topical Anti-Inflammatory and Antipyretic Potentialities of Araucaria bidiwillii Shoot Essential Oil and Its Nanoemulsion in Relation to Chemical Composition.
Autorzy:: Abdelhameed MF; Pharmacology Department, National Research Centre, Dokki, Giza 12622, Egypt.
Asaad GF; Pharmacology Department, National Research Centre, Dokki, Giza 12622, Egypt.
Ragab TIM; Chemistry of Natural and Micro and al Products Department, National Research Centre, Dokki, Giza 12622, Egypt.
Ahmed RF; Chemistry of Natural Compounds Department, National Research Center, 33 El Bohouth St., Dokki, Giza 12622, Egypt.
El Gendy AEG; Medicinal and Aromatic Plants Research Department, National Research Centre, 33 El Bohouth St., Dokki, Giza 12622, Egypt.
Abd El-Rahman SS; Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.
Elgamal AM; Department of Chemistry of Microbial and Natural Products, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt.
Elshamy AI; Chemistry of Natural Compounds Department, National Research Center, 33 El Bohouth St., Dokki, Giza 12622, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Sep 26; Vol. 26 (19). Date of Electronic Publication: 2021 Sep 26.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Antipyretics/*pharmacology
Araucaria/*chemistry
Edema/*drug therapy
Fever/*drug therapy
Inflammation/*drug therapy
Oils, Volatile/*pharmacology
Animals ; Carrageenan/adverse effects ; Edema/chemically induced ; Edema/pathology ; Emulsions ; Inflammation/chemically induced ; Inflammation/pathology ; Male ; Pain/drug therapy ; Plant Extracts/pharmacology ; Plant Shoots/chemistry ; Rats ; Rats, Wistar

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Skocz do pozycji: 9.

Tytuł:: Anti-Inflammatory, Antipyretic, and Analgesic Properties of Potamogeton perfoliatus Extract: In Vitro and In Vivo Study.
Autorzy:: Rezq S; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Mahmoud MF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
El-Shazly AM; Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
El Raey MA; National Research Centre, Department of Phytochemistry and Plant Systematics, Pharmaceutical Division, Dokki, Cairo 12622, Egypt.
Sobeh M; AgroBioSciences Research, Mohammed VI Polytechnic University, Lot 660-Hay MoulayRachid, Ben-Guerir 43150, Morocco.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Aug 10; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 10.
Typ publikacji:: Journal Article
MeSH Terms:: Analgesics/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Antipyretics/*pharmacology
Plant Extracts/*pharmacology
Potamogetonaceae/*chemistry
Acetic Acid ; Animals ; Antioxidants/pharmacology ; Behavior, Animal/drug effects ; Capillary Permeability/drug effects ; Carrageenan ; Cell Movement/drug effects ; Chromatography, High Pressure Liquid ; Drug Evaluation, Preclinical ; Edema/pathology ; Fever/pathology ; Iridoid Glucosides/pharmacology ; Leukocytes/drug effects ; Male ; Mice ; Peritoneal Cavity/pathology ; Phenylpropionates/pharmacology ; Phytochemicals/analysis ; Rats ; Saccharomyces cerevisiae

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Skocz do pozycji: 10.

Tytuł:: Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs.
Autorzy:: Benvenutti L; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Nunes R; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Venturi I; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Ramos SA; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Broering MF; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Goldoni FC; School of Health Sciences, Biomedicine Course, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Pavan SE; School of Health Sciences, Biomedicine Course, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Pastor MVD; School of Health Sciences, Biomedicine Course, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Malheiros A; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.; School of Health Sciences, Biomedicine Course, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Quintão NLM; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.; School of Health Sciences, Biomedicine Course, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.
Fernandes ES; Programa de Pós-graduação em Biotecnologia Aplicada à Saúde da Criança e do Adolescente, Faculdades Pequeno Príncipe, Av. Iguaçu, 333, Curitiba, PR 80230-020, Brazil.; Instituto de Pesquisa Pelé Pequeno Príncipe, Av. Silva Jardim, 1632, Curitiba, PR 80250-060, Brazil.
Santin JR; Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.; School of Health Sciences, Biomedicine Course, Universidade do Vale do Itajaí, Rua Uruguai, 458, Itajaí, SC 88302-202, Brazil.; Pokaż więcej
Źródło:: Journal of immunology research [J Immunol Res] 2021 Jul 19; Vol. 2021, pp. 9957451. Date of Electronic Publication: 2021 Jul 19 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Inflammation/*drug therapy
Plant Extracts/*pharmacology
Solanum/*chemistry
Wound Healing/*drug effects
Animals ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/therapeutic use ; Carrageenan/administration & dosage ; Carrageenan/immunology ; Chemotaxis, Leukocyte/drug effects ; Disease Models, Animal ; Female ; Fruit/chemistry ; Humans ; Inflammation/immunology ; Male ; Mice ; Neutrophils/drug effects ; Neutrophils/immunology ; Plant Extracts/isolation & purification ; Plant Extracts/therapeutic use ; Rats ; Toxicity Tests, Acute ; Toxicity Tests, Subacute ; Wound Healing/immunology

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Skocz do pozycji: 11.

Tytuł:: (-)-Englerin-A Has Analgesic and Anti-Inflammatory Effects Independent of TRPC4 and 5.
Autorzy:: de Sousa Valente J; Section of Vascular Biology and Inflammation, BHF Cardiovascular Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK.
Alawi KM; Section of Vascular Biology and Inflammation, BHF Cardiovascular Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK.
Bharde S; Section of Vascular Biology and Inflammation, BHF Cardiovascular Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK.
Zarban AA; Section of Vascular Biology and Inflammation, BHF Cardiovascular Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK.; Department of Pharmacological Sciences, Faculty of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.
Kodji X; Section of Vascular Biology and Inflammation, BHF Cardiovascular Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK.
Thapa D; Section of Vascular Biology and Inflammation, BHF Cardiovascular Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK.
Argunhan F; Section of Vascular Biology and Inflammation, BHF Cardiovascular Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK.
Barrett B; Section of Vascular Biology and Inflammation, BHF Cardiovascular Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK.
Nagy I; Nociception Group, Section of Anaesthetic, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, London SW7 2AZ, UK.
Brain SD; Section of Vascular Biology and Inflammation, BHF Cardiovascular Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, Franklin-Wilkins Building, London SE1 9NH, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 15; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 15.
Typ publikacji:: Journal Article
MeSH Terms:: Analgesics/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Sesquiterpenes, Guaiane/*pharmacology
TRPC Cation Channels/*metabolism
Analgesics/therapeutic use ; Animals ; Anti-Inflammatory Agents/therapeutic use ; Behavior, Animal/drug effects ; Carrageenan ; Cells, Cultured ; Cobalt/metabolism ; Disease Models, Animal ; Edema/pathology ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/metabolism ; Hyperalgesia/drug therapy ; Inflammation/complications ; Inflammation/drug therapy ; Inflammation/pathology ; Male ; Mice, Knockout ; Pain/complications ; Pain/drug therapy ; Pain/pathology ; Phenotype ; Sensory Receptor Cells/drug effects ; Sensory Receptor Cells/metabolism ; Sesquiterpenes, Guaiane/therapeutic use ; Mice

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Skocz do pozycji: 12.

Tytuł:: Characterization of N -Octadecanoyl-5-hydroxytryptamide Anti-Inflammatory Effect.
Autorzy:: Giorno TBS; Laboratório de Farmacologia da Dor e da Inflamação, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Lima FA; Laboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Brand ALM; Laboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Oliveira CM; Laboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Rezende CM; Laboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Fernandes PD; Laboratório de Farmacologia da Dor e da Inflamação, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Jun 18; Vol. 26 (12). Date of Electronic Publication: 2021 Jun 18.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Inflammation/*drug therapy
Serotonin/*pharmacology
Animals ; Carrageenan/pharmacology ; Cell Line ; Cell Movement/drug effects ; Cytokines/metabolism ; Disease Models, Animal ; Inflammation/chemically induced ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Interleukin-10/metabolism ; Leukocytes/drug effects ; Leukocytes/metabolism ; Macrophages/drug effects ; Macrophages/metabolism ; Male ; Mice ; Nitric Oxide/metabolism ; RAW 264.7 Cells

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Tytuł:: 2-Arachidonyl-lysophosphatidylethanolamine Induces Anti-Inflammatory Effects on Macrophages and in Carrageenan-Induced Paw Edema.
Autorzy:: Park SJ; College of Pharmacy, Pusan National University, Busan 46241, Korea.
Im DS; College of Pharmacy, Pusan National University, Busan 46241, Korea.; Laboratory of Pharmacology, College of Pharmacy, and Department of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 May 04; Vol. 22 (9). Date of Electronic Publication: 2021 May 04.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Arachidonic Acids/*pharmacology
Edema/*drug therapy
Lysophospholipids/*pharmacology
Macrophages, Peritoneal/*drug effects
Animals ; Anti-Inflammatory Agents/chemistry ; Arachidonic Acids/chemistry ; Carrageenan/administration & dosage ; Cyclooxygenase 2/immunology ; Dinoprostone/antagonists & inhibitors ; Dinoprostone/biosynthesis ; Edema/chemically induced ; Edema/immunology ; Edema/pathology ; Hindlimb/drug effects ; Hindlimb/immunology ; Hindlimb/metabolism ; Interleukin-12 Subunit p35/antagonists & inhibitors ; Interleukin-12 Subunit p35/immunology ; Interleukin-1beta/antagonists & inhibitors ; Interleukin-1beta/immunology ; Lipopolysaccharides/antagonists & inhibitors ; Lipopolysaccharides/pharmacology ; Lysophospholipids/chemistry ; Macrophages, Peritoneal/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Nitric Oxide/antagonists & inhibitors ; Nitric Oxide/biosynthesis ; Nitric Oxide Synthase Type II/antagonists & inhibitors ; Nitric Oxide Synthase Type II/immunology ; Primary Cell Culture ; Treatment Outcome

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Tytuł:: Anti-Inflammatory and Antimicrobial Activities of Compounds Isolated from Distichochlamys benenica .
Autorzy:: Pham TV; Faculty of Chemistry, University of Education, Hue University, 34 Le Loi, Hue City, Vietnam.
Hoang HNT; Faculty of Engineering and Food Technology, Hue University of Agriculture and Forestry, Hue University, 102 Phung Hung, Hue City, Vietnam.
Nguyen HT; Faculty of Pharmacy, University of Medicine and Pharmacy, Hue University, 06 Ngo Quyen, Hue City, Vietnam.
Nguyen HM; Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Huynh CT; Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Vu TY; Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Do AT; English Faculty, Foreign Trade University-Ho Chi Minh City Campus, Vietnam.
Nguyen NH; Faculty of Biotechnology, Ho Chi Minh City Open University, Ho Chi Minh City, Vietnam.
Do BH; Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Vietnam.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2021 Apr 06; Vol. 2021, pp. 6624347. Date of Electronic Publication: 2021 Apr 06 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Infective Agents/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Phytochemicals/*isolation & purification
Phytochemicals/*pharmacology
Zingiberaceae/*chemistry
Animals ; Anti-Infective Agents/chemistry ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/therapeutic use ; Bacteria/drug effects ; Binding Sites ; Carrageenan ; Coumaric Acids/chemistry ; Coumaric Acids/pharmacology ; Coumaric Acids/therapeutic use ; Cyclooxygenase 2/metabolism ; Diclofenac/administration & dosage ; Diclofenac/pharmacology ; Diclofenac/therapeutic use ; Edema/drug therapy ; Edema/pathology ; Mice ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Phytochemicals/chemistry ; Phytochemicals/therapeutic use

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Skocz do pozycji: 15.

Tytuł:: New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5 H )ones as Possible Anti-Inflammatory Agents.
Autorzy:: Tratrat C; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Haroun M; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Paparisva A; School of Pharmacy, University of Thessaloniki, 54124 Thessaloniki, Greece.
Kamoutsis C; School of Pharmacy, University of Patras, 26504 Patra, Greece.
Petrou A; School of Pharmacy, University of Thessaloniki, 54124 Thessaloniki, Greece.
Gavalas A; School of Pharmacy, University of Thessaloniki, 54124 Thessaloniki, Greece.
Eleftheriou P; Department of Biomedical Sciences, School of Health Sciences, International Hellenic University, 57400 Thessaloniki, Greece.
Geronikaki A; School of Pharmacy, University of Thessaloniki, 54124 Thessaloniki, Greece.
Venugopala KN; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.; Department of Biotechnology and Food Technology, Durban University of Technology, Durban 4001, South Africa.
Kochkar H; Department of Chemistry, College of Science, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.; Basic & Applied Scientific Research Center, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Nair AB; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Jan 27; Vol. 26 (3). Date of Electronic Publication: 2021 Jan 27.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Triazoles/*pharmacology
Animals ; Arachidonic Acid/pharmacology ; Carrageenan/pharmacology ; Cyclooxygenase 1/metabolism ; Cyclooxygenase 2/metabolism ; Cyclooxygenase 2 Inhibitors/pharmacology ; Cyclooxygenase Inhibitors/pharmacology ; Edema/chemically induced ; Edema/drug therapy ; Edema/metabolism ; Female ; Humans ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/metabolism ; Lipoxygenase/metabolism ; Lipoxygenase Inhibitors/pharmacology ; Male ; Mice ; Molecular Docking Simulation ; Naproxen/pharmacology ; Structure-Activity Relationship

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Skocz do pozycji: 16.

Tytuł:: Caralluma europaea (Guss.) N.E.Br.: Anti-Inflammatory, Antifungal, and Antibacterial Activities against Nosocomial Antibiotic-Resistant Microbes of Chemically Characterized Fractions.
Autorzy:: Amrati FE; Laboratory of Biotechnology, Health, Agrofood and Environment (LBEAS), Faculty of Sciences Dhar El Mehraz, Sidi Mohamed Ben Abdellah University, Fez 30000, Morocco.
Bourhia M; Laboratory of Chemistry, Biochemistry, Nutrition, and Environment, Faculty of Medicine and Pharmacy, University Hassan II, Casablanca 20000, Morocco.
Saghrouchni H; Department of Biotechnology, Institute of Natural and Applied Sciences, Çukurova University, Adana 01170, Turkey.
Slighoua M; Laboratory of Biotechnology, Health, Agrofood and Environment (LBEAS), Faculty of Sciences Dhar El Mehraz, Sidi Mohamed Ben Abdellah University, Fez 30000, Morocco.
Grafov A; Department of Chemistry, Faculty of Sciences, Helsinki University, 00100 Helsinki, Finland.
Ullah R; Department of Pharmacognosy (MAPPRC), College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Ezzeldin E; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Mostafa GA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Bari A; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Ibenmoussa S; Laboratory of Chemistry, Biochemistry, Nutrition, and Environment, Faculty of Medicine and Pharmacy, University Hassan II, Casablanca 20000, Morocco.
Bousta D; Laboratory of Biotechnology, Health, Agrofood and Environment (LBEAS), Faculty of Sciences Dhar El Mehraz, Sidi Mohamed Ben Abdellah University, Fez 30000, Morocco.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Jan 26; Vol. 26 (3). Date of Electronic Publication: 2021 Jan 26.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Infective Agents/*administration & dosage
Anti-Inflammatory Agents/*administration & dosage
Apocynaceae/*chemistry
Cross Infection/*microbiology
Inflammation/*drug therapy
Phytochemicals/*administration & dosage
1-Butanol/administration & dosage ; 1-Butanol/isolation & purification ; 1-Butanol/pharmacology ; Animals ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/isolation & purification ; Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents/isolation & purification ; Anti-Infective Agents/pharmacology ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology ; Antifungal Agents/administration & dosage ; Antifungal Agents/isolation & purification ; Antifungal Agents/pharmacology ; Candida albicans/drug effects ; Carrageenan/adverse effects ; Cross Infection/drug therapy ; Drug Resistance, Bacterial/drug effects ; Drug Resistance, Fungal/drug effects ; Female ; Gas Chromatography-Mass Spectrometry ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Humans ; Inflammation/chemically induced ; Male ; Microbial Sensitivity Tests ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Polyphenols/administration & dosage ; Polyphenols/isolation & purification ; Polyphenols/pharmacology ; Rats ; Saccharomyces cerevisiae/drug effects

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Tytuł:: Molecular Insight into the Anti-Inflammatory Effects of the Curcumin Ester Prodrug Curcumin Diglutaric Acid In Vitro and In Vivo.
Autorzy:: Phumsuay R; Inter-Department Program of Pharmacology, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand.
Muangnoi C; Institute of Nutrition, Mahidol University, Salaya, Nakhon Pathom 73170, Thailand.
Dasuni Wasana PW; Pharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Hasriadi; Pharmaceutical Sciences and Technology Program, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Vajragupta O; Research Affairs, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Rojsitthisak P; Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.; Natural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok 10330, Thailand.
Towiwat P; Natural Products for Ageing and Chronic Diseases Research Unit, Chulalongkorn University, Bangkok 10330, Thailand.; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Aug 09; Vol. 21 (16). Date of Electronic Publication: 2020 Aug 09.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Curcumin/*pharmacology
Esters/*pharmacology
Prodrugs/*pharmacology
Animals ; Anti-Inflammatory Agents/chemistry ; Carrageenan ; Cell Survival/drug effects ; Curcumin/chemistry ; Cytokines/metabolism ; Edema/chemically induced ; Edema/metabolism ; Edema/prevention & control ; Hindlimb ; Inflammation Mediators/metabolism ; Lipopolysaccharides/pharmacology ; Male ; Mice ; Mice, Inbred ICR ; Nitric Oxide/metabolism ; Nitric Oxide Synthase Type II/metabolism ; Prodrugs/chemistry ; RAW 264.7 Cells

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Skocz do pozycji: 18.

Tytuł:: Benzylideneacetophenone Derivative Alleviates Arthritic Symptoms via Modulation of the MAPK Signaling Pathway.
Autorzy:: Sur B; Department of Molecular Medicine, School of Medicine, Ewha Womans University, Seoul 07804, Korea.
Kim M; Department of Molecular Medicine, School of Medicine, Ewha Womans University, Seoul 07804, Korea.
Villa T; Department of Molecular Medicine, School of Medicine, Ewha Womans University, Seoul 07804, Korea.
Oh S; Department of Molecular Medicine, School of Medicine, Ewha Womans University, Seoul 07804, Korea.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Jul 22; Vol. 25 (15). Date of Electronic Publication: 2020 Jul 22.
Typ publikacji:: Journal Article
MeSH Terms:: Anti-Inflammatory Agents/*chemistry
Arthritis, Rheumatoid/*drug therapy
Chalcone/*chemistry
Chalcone/*pharmacology
Animals ; Anti-Inflammatory Agents/pharmacology ; Arthritis, Experimental/drug therapy ; Carrageenan/metabolism ; Chalcone/analogs & derivatives ; Cytokines/metabolism ; Dose-Response Relationship, Drug ; Drug Design ; Fibroblasts/metabolism ; Humans ; Kaolin/metabolism ; Knee ; MAP Kinase Signaling System ; Male ; NF-kappa B/metabolism ; Prostaglandins E/metabolism ; Rats ; Rats, Sprague-Dawley ; Synoviocytes/cytology ; Synoviocytes/drug effects

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Skocz do pozycji: 19.

Tytuł:: Attenuation of Inflammatory Symptoms by Icariside B2 in Carrageenan and LPS-Induced Inflammation Models via Regulation of MAPK/NF-κB Signaling Cascades.
Autorzy:: Alam MB; School of Food Science and Biotechnology, Graduate School, Kyungpook National University, Daegu 41566, Korea.; Food and Bio-Industry Research Institute, Inner Beauty/Antiaging Center, Kyungpook National University, Daegu 41566, Korea.
Kwon YG; School of Food Science and Biotechnology, Graduate School, Kyungpook National University, Daegu 41566, Korea.
Simu SY; Department of Brain Science, Ajou University School of Medicine, Suwon, 16499, Korea.
Abrar Shahriyar S; Biomedical Science, Graduate School, Ajou University School of Medicine, Suwon 16499, Korea.
Lee SH; School of Food Science and Biotechnology, Graduate School, Kyungpook National University, Daegu 41566, Korea.; Food and Bio-Industry Research Institute, Inner Beauty/Antiaging Center, Kyungpook National University, Daegu 41566, Korea.; knu BnC, Kyungpook National University, Daegu 41566, Korea.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2020 Jul 11; Vol. 10 (7). Date of Electronic Publication: 2020 Jul 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anti-Inflammatory Agents/*administration & dosage
Carrageenan/*adverse effects
Cyclohexanones/*chemistry
Edema/*drug therapy
Epimedium/*chemistry
Glucosides/*chemistry
Lipopolysaccharides/*adverse effects
Norisoprenoids/*chemistry
Animals ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Disease Models, Animal ; Edema/chemically induced ; Edema/metabolism ; Gene Expression Regulation/drug effects ; MAP Kinase Signaling System/drug effects ; Mice ; Models, Molecular ; Molecular Conformation ; Molecular Docking Simulation ; NF-kappa B/metabolism ; Phosphorylation/drug effects ; Plant Extracts/chemistry

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Skocz do pozycji: 20.

Tytuł:: Role of water in cyclooxygenase catalysis and design of anti-inflammatory agents targeting two sites of the enzyme.
Autorzy:: Kaur M; UGC Sponsored Centre for Advanced Studies, Department of Chemistry, Guru Nanak Dev University, Amritsar, 143005, India.
Kaur B; UGC Sponsored Centre for Advanced Studies, Department of Chemistry, Guru Nanak Dev University, Amritsar, 143005, India.
Kaur J; UGC Sponsored Centre for Advanced Studies, Department of Chemistry, Guru Nanak Dev University, Amritsar, 143005, India.
Kaur A; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, 143005, India.
Bhatti R; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, 143005, India.
Singh P; UGC Sponsored Centre for Advanced Studies, Department of Chemistry, Guru Nanak Dev University, Amritsar, 143005, India. palwinder_singh_.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Jul 01; Vol. 10 (1), pp. 10764. Date of Electronic Publication: 2020 Jul 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anti-Inflammatory Agents/*pharmacology
Cyclooxygenase 2/*chemistry
Cyclooxygenase 2 Inhibitors/*pharmacology
Water/*chemistry
Analgesics/pharmacology ; Animals ; Carrageenan/chemistry ; Catalysis ; Drug Design ; Electrons ; Female ; Formaldehyde/chemistry ; Heme/chemistry ; Hydrogen/chemistry ; Hydrogen-Ion Concentration ; Inflammation ; Inhibitory Concentration 50 ; Kinetics ; Male ; Mice ; Molecular Dynamics Simulation ; Peptides/chemistry ; Thermodynamics

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