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Wyszukujesz frazę ""Carrier Proteins"" wg kryterium: Temat


Tytuł:
Rational exploration of fold atlas for human solute carrier proteins.
Autorzy:
Xie T; Westlake Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China; Institute of Biology, Westlake Institute for Advanced Study, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China; Westlake AI Therapeutics Lab, Westlake Laboratory of Life Sciences and Biomedicine, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China.
Chi X; Westlake Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China; Institute of Biology, Westlake Institute for Advanced Study, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China.
Huang B; Westlake Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China; Institute of Biology, Westlake Institute for Advanced Study, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China.
Ye F; Westlake Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China; Institute of Biology, Westlake Institute for Advanced Study, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China.
Zhou Q; Westlake Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China; Institute of Biology, Westlake Institute for Advanced Study, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China. Electronic address: .
Huang J; Westlake Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China; Institute of Biology, Westlake Institute for Advanced Study, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China; Westlake AI Therapeutics Lab, Westlake Laboratory of Life Sciences and Biomedicine, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China. Electronic address: .
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Źródło:
Structure (London, England : 1993) [Structure] 2022 Sep 01; Vol. 30 (9), pp. 1321-1330.e5. Date of Electronic Publication: 2022 Jun 13.
Typ publikacji:
Journal Article
MeSH Terms:
Membrane Transport Proteins*/metabolism
Solute Carrier Proteins*/metabolism
Biological Transport ; Humans
Czasopismo naukowe
Tytuł:
Mutant WDR45 Leads to Altered Ferritinophagy and Ferroptosis in β-Propeller Protein-Associated Neurodegeneration.
Autorzy:
Diaw SH; Institute of Neurogenetics, University of Lübeck, 23562 Lübeck, Germany.
Ganos C; Department of Neurology, Charité-University Medicine, 10117 Berlin, Germany.
Zittel S; Department of Neurology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Plötze-Martin K; Institute of Neurogenetics, University of Lübeck, 23562 Lübeck, Germany.
Kulikovskaja L; Institute of Neurogenetics, University of Lübeck, 23562 Lübeck, Germany.
Vos M; Institute of Neurogenetics, University of Lübeck, 23562 Lübeck, Germany.
Westenberger A; Institute of Neurogenetics, University of Lübeck, 23562 Lübeck, Germany.
Rakovic A; Institute of Neurogenetics, University of Lübeck, 23562 Lübeck, Germany.
Lohmann K; Institute of Neurogenetics, University of Lübeck, 23562 Lübeck, Germany.
Dulovic-Mahlow M; Institute of Neurogenetics, University of Lübeck, 23562 Lübeck, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 23; Vol. 23 (17). Date of Electronic Publication: 2022 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Carrier Proteins*/genetics
Carrier Proteins*/metabolism
Ferroptosis*/genetics
Neurodegenerative Diseases*/genetics
Autophagy/genetics ; Brain/metabolism ; Female ; Humans ; Iron/metabolism ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł:
Downregulation of Inflammatory Response via Nrf2/Trx1/TXNIP Axis in Oxidative Stress-Induced ARPE-19 Cells and Mouse Model of AMD.
Autorzy:
Yang Q; Department of Ophthalmology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200072, China.
Cai W; Department of Ophthalmology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200072, China.
Jin H; Department of Ophthalmology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200072, China.
Shen T; Department of Ophthalmology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200072, China.
Yu J; Department of Ophthalmology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200072, China.
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Źródło:
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2022 Aug 12; Vol. 2022, pp. 1497813. Date of Electronic Publication: 2022 Aug 12 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Carrier Proteins*/genetics
Carrier Proteins*/metabolism
Macular Degeneration*/genetics
Macular Degeneration*/metabolism
NF-E2-Related Factor 2*/genetics
NF-E2-Related Factor 2*/metabolism
Thioredoxins*/genetics
Thioredoxins*/metabolism
Animals ; Disease Models, Animal ; Down-Regulation ; GA-Binding Protein Transcription Factor ; Humans ; Hydrogen Peroxide ; Inflammasomes ; Inflammation ; Mice ; NLR Family, Pyrin Domain-Containing 3 Protein ; Oxidative Stress ; Reactive Oxygen Species ; Retinal Diseases/genetics ; Retinal Diseases/metabolism
Czasopismo naukowe
Tytuł:
ATG16L2 inhibits NLRP3 inflammasome activation through promoting ATG5-12-16L1 complex assembly and autophagy.
Autorzy:
Wang D; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuan T; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Liu J; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine, Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wen Z; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shen Y; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tang J; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang Z; Department of Gastrointestinal Surgery, Renji Hospital Affiliated, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wu X; Hongqiao International Institute of Medicine, Shanghai Tongren Hospital/Faculty of Basic Medicine, Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Źródło:
European journal of immunology [Eur J Immunol] 2022 Aug; Vol. 52 (8), pp. 1321-1334. Date of Electronic Publication: 2022 Apr 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Autophagy-Related Protein 5*/genetics
Autophagy-Related Protein 5*/metabolism
Carrier Proteins*/genetics
Carrier Proteins*/metabolism
Inflammasomes*/metabolism
NLR Family, Pyrin Domain-Containing 3 Protein*/genetics
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Animals ; Autophagy ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Tytuł:
Inhibition of GAB2 expression has a protective effect on osteoarthritis:An in vitro and in vivo study.
Autorzy:
Mo H; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang S; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chen AM; Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Oct 20; Vol. 626, pp. 229-235. Date of Electronic Publication: 2022 Aug 12.
Typ publikacji:
Journal Article
MeSH Terms:
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
Carrier Proteins*/metabolism
Osteoarthritis*/metabolism
Animals ; Cells, Cultured ; Chondrocytes/metabolism ; Interleukin-1beta/metabolism ; Mice ; NF-kappa B/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
Cryo-EM structure studies of the human VPS10 domain-containing receptor SorCS3.
Autorzy:
Dong F; The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518000, Guangdong Province, China; Shenzhen University General Hospital, Shenzhen, 518000, Guangdong Province, China.
Wu C; Southern University of Science and Technology, Shenzhen, 518055, Guangdong Province, China.
Jiang W; South China Hospital of Shenzhen University, Shenzhen, 518111, Guangdong Province, China.
Zhai M; Shenzhen University General Hospital, Shenzhen, 518000, Guangdong Province, China.
Li H; The University of Hong Kong-Shenzhen Hospital, Shenzhen, 518000, Guangdong Province, China. Electronic address: .
Zhai L; Stanford University, Stanford, CA 94305, California, USA. Electronic address: .
Zhang X; Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences, Shenzhen, 518055, Guangdong Province, China; Shenzhen People's Second Hospital, Shenzhen, 518000, Guangdong Province, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Oct 08; Vol. 624, pp. 89-94. Date of Electronic Publication: 2022 Jul 16.
Typ publikacji:
Journal Article
MeSH Terms:
Carrier Proteins*/metabolism
Nerve Tissue Proteins*/metabolism
Cryoelectron Microscopy ; Humans ; Protein Binding ; Protein Transport ; Receptors, Cell Surface/metabolism
Czasopismo naukowe
Tytuł:
Laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS)-based strategies applied for the analysis of metal-binding protein in biological samples: an update on recent advances.
Autorzy:
Chen J; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Wang R; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Ma M; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Gao L; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China.; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Zhao B; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China.; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.
Xu M; School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China. .; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China. .; University of Chinese Academy of Sciences, Beijing, 100049, China. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2022 Oct; Vol. 414 (24), pp. 7023-7033. Date of Electronic Publication: 2022 Jul 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carrier Proteins*
Laser Therapy*
Chelating Agents ; Mass Spectrometry/methods ; Metals/analysis ; Proteins/chemistry
Czasopismo naukowe
Tytuł:
De novo design of membrane transport proteins.
Autorzy:
Zhou C; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.
Lu P; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.; Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.
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Źródło:
Proteins [Proteins] 2022 Oct; Vol. 90 (10), pp. 1800-1806. Date of Electronic Publication: 2022 Mar 26.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Carrier Proteins*/chemistry
Membrane Transport Proteins*/chemistry
Biological Transport
Czasopismo naukowe
Tytuł:
Cross reacting material (CRM197) as a carrier protein for carbohydrate conjugate vaccines targeted at bacterial and fungal pathogens.
Autorzy:
Khatuntseva EA; Laboratory of Glycoconjugate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, 119991, Russia.
Nifantiev NE; Laboratory of Glycoconjugate Chemistry, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, 119991, Russia. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2022 Oct 01; Vol. 218, pp. 775-798. Date of Electronic Publication: 2022 Jul 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Bacterial Proteins*
Carrier Proteins*
Bacteria ; Bacterial Vaccines ; Carbohydrates ; Vaccines, Conjugate
Czasopismo naukowe
Tytuł:
Targeting the ATG5-ATG16L1 Protein-Protein Interaction with a Hydrocarbon-Stapled Peptide Derived from ATG16L1 for Autophagy Inhibition.
Autorzy:
Cui J; Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki Shinagawa-ku, Tokyo, 141-0021, Japan.
Ogasawara Y; Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki Shinagawa-ku, Tokyo, 141-0021, Japan.
Kurata I; Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki Shinagawa-ku, Tokyo, 141-0021, Japan.
Matoba K; Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki Shinagawa-ku, Tokyo, 141-0021, Japan.
Fujioka Y; Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki Shinagawa-ku, Tokyo, 141-0021, Japan.
Noda NN; Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki Shinagawa-ku, Tokyo, 141-0021, Japan.
Shibasaki M; Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki Shinagawa-ku, Tokyo, 141-0021, Japan.
Watanabe T; Institute of Microbial Chemistry (BIKAKEN), Tokyo, 3-14-23 Kamiosaki Shinagawa-ku, Tokyo, 141-0021, Japan.
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Źródło:
Journal of the American Chemical Society [J Am Chem Soc] 2022 Sep 28; Vol. 144 (38), pp. 17671-17679. Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:
Journal Article
MeSH Terms:
Carrier Proteins*/metabolism
Microtubule-Associated Proteins*/metabolism
Autophagy ; Autophagy-Related Protein 5/metabolism ; Autophagy-Related Proteins/metabolism ; Hydrocarbons ; Peptides/metabolism ; Peptides/pharmacology
Czasopismo naukowe
Tytuł:
Identification of ASPDH as a novel NAADP-binding protein.
Autorzy:
He X; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Peking University, Beijing, 100871, China; National Biomedical Imaging Center, Peking University, Beijing, 100871, China.
Kang Y; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Peking University, Beijing, 100871, China; National Biomedical Imaging Center, Peking University, Beijing, 100871, China.
Chen L; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Peking University, Beijing, 100871, China; National Biomedical Imaging Center, Peking University, Beijing, 100871, China; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Sep 17; Vol. 621, pp. 168-175. Date of Electronic Publication: 2022 Jul 04.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium Signaling*
Carrier Proteins*/metabolism
Animals ; Calcium/metabolism ; Calcium Channels/metabolism ; Carboxy-Lyases/metabolism ; Mice ; NADP/analogs & derivatives ; NADP/metabolism ; Swine
Czasopismo naukowe
Tytuł:
Adsorption of ice-binding proteins onto whole ice crystal surfaces does not necessarily confer a high thermal hysteresis activity.
Autorzy:
Arai T; Department of Advanced Materials Science, Graduate School of Frontier Sciences, The University of Tokyo, 7H8 #609 Kiban Bldg., 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8561, Japan. .; AIST-UTokyo Advanced Operando Measurement Technology Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Kashiwa, 277-0882, Japan. .
Yamauchi A; Hibernation Metabolism, Physiology and Development Group, Institute of Low Temperature Science, Hokkaido University, Sapporo, 060-0819, Japan.
Yang Y; Department of Advanced Materials Science, Graduate School of Frontier Sciences, The University of Tokyo, 7H8 #609 Kiban Bldg., 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8561, Japan.
Singh SM; Department of Botany, Banaras Hindu University (BHU), Varanasi, 221005, India.
Sasaki YC; Department of Advanced Materials Science, Graduate School of Frontier Sciences, The University of Tokyo, 7H8 #609 Kiban Bldg., 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8561, Japan.; AIST-UTokyo Advanced Operando Measurement Technology Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Kashiwa, 277-0882, Japan.
Tsuda S; Department of Advanced Materials Science, Graduate School of Frontier Sciences, The University of Tokyo, 7H8 #609 Kiban Bldg., 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8561, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Sep 14; Vol. 12 (1), pp. 15443. Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antifreeze Proteins*/chemistry
Carrier Proteins*/metabolism
Adsorption ; Caspase 1/metabolism ; Ice Cover ; Organothiophosphorus Compounds
Czasopismo naukowe
Tytuł:
Amidosquaramides - a new anion binding motif with pH sensitive anion transport properties.
Autorzy:
Marchetti LA; Department of Chemistry, National University of Ireland Maynooth, Maynooth, Ireland. .
Krämer T; Department of Chemistry, National University of Ireland Maynooth, Maynooth, Ireland. .
Elmes RBP; Department of Chemistry, National University of Ireland Maynooth, Maynooth, Ireland. .; Synthesis and Solid State Pharmaceutical Centre (SSPC), Ireland.
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Źródło:
Organic & biomolecular chemistry [Org Biomol Chem] 2022 Sep 14; Vol. 20 (35), pp. 7056-7066. Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carrier Proteins*
Anions/chemistry ; Hydrogen-Ion Concentration ; Ion Transport
Czasopismo naukowe
Tytuł:
A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria.
Autorzy:
Gude F; Research Unit Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Adolf-Reichwein-Straße 23, 07745, Jena, Germany.
Molloy EM; Research Unit Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Adolf-Reichwein-Straße 23, 07745, Jena, Germany.
Horch T; Research Unit Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Adolf-Reichwein-Straße 23, 07745, Jena, Germany.
Dell M; Research Unit Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Adolf-Reichwein-Straße 23, 07745, Jena, Germany.
Dunbar KL; Research Unit Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Adolf-Reichwein-Straße 23, 07745, Jena, Germany.
Krabbe J; Research Unit Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Adolf-Reichwein-Straße 23, 07745, Jena, Germany.
Groll M; Center for Protein Assemblies, Technical University of Munich, Ernst-Otto-Fischer-Straße 8, 85747, Garching, Germany.
Hertweck C; Research Unit Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Adolf-Reichwein-Straße 23, 07745, Jena, Germany.; Faculty of Biological Sciences, Friedrich Schiller University Jena, 07743, Jena, Germany.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Sep 12; Vol. 61 (37), pp. e202206168. Date of Electronic Publication: 2022 Aug 03.
Typ publikacji:
Journal Article
MeSH Terms:
Bacteria, Anaerobic*/genetics
Carrier Proteins*/genetics
Anti-Bacterial Agents/chemistry ; Drug Resistance, Microbial ; Gene Editing
Czasopismo naukowe
Tytuł:
Condensing our understanding of endocytosis.
Autorzy:
Panzera LC; Dartmouth College, Department of Biological Sciences, Hanover, NH, USA.
Hoppa MB; Dartmouth College, Department of Biological Sciences, Hanover, NH, USA. Electronic address: .
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Źródło:
Neuron [Neuron] 2022 Sep 07; Vol. 110 (17), pp. 2705-2707.
Typ publikacji:
Journal Article; Comment
MeSH Terms:
Carrier Proteins*/metabolism
Synaptic Vesicles*/metabolism
Dynamins/metabolism ; Endocytosis/physiology ; Neurons/metabolism
Czasopismo naukowe
Tytuł:
86Y-Labeled Albumin-Binding Fibroblast Activation Protein Inhibitor for Late-Time-Point Cancer Diagnosis.
Autorzy:
Ding J; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Xu M; Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Chen J; Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Zhang P; Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Huo L; Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Kong Z; Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Liu Z; Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.; Peking University-Tsinghua University Center for Life Sciences, Peking University, Beijing 100871, China.
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Źródło:
Molecular pharmaceutics [Mol Pharm] 2022 Sep 05; Vol. 19 (9), pp. 3429-3438. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carrier Proteins*/metabolism
Neoplasms*/drug therapy
Neoplasms*/metabolism
Albumins/metabolism ; Fibroblasts/metabolism ; Gallium Radioisotopes/metabolism ; Humans ; Membrane Proteins/metabolism ; Positron Emission Tomography Computed Tomography ; Tissue Distribution
Czasopismo naukowe
Tytuł:
Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt.
Autorzy:
Yu Z; Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA.
Chen J; Department of Medicine, Division of Nephrology, and Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA.
Takagi E; Department of Medicine, Division of Nephrology, and Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA.
Wang F; Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA.
Saha B; Department of Medicine, Division of Nephrology, and Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA.
Liu X; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, USA.
Joubert LM; Division of CryoEM and Bioimaging, SSRL, SLAC National Accelerator Laboratory, Stanford University, Menlo Park, California, USA.
Gleason CE; Department of Medicine, Division of Nephrology, and Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA.
Jin M; Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA.
Li C; Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA.
Nowotny C; Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA.
Agard D; Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA.
Cheng Y; Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA; Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California, USA.
Pearce D; Department of Medicine, Division of Nephrology, and Department of Cellular and Molecular Pharmacology, UCSF, San Francisco, California, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Sep; Vol. 298 (9), pp. 102288. Date of Electronic Publication: 2022 Aug 01.
Typ publikacji:
Journal Article
MeSH Terms:
Carrier Proteins*/metabolism
Monomeric GTP-Binding Proteins*/metabolism
Humans ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mechanistic Target of Rapamycin Complex 2/genetics ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Phosphorylation ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Rapamycin-Insensitive Companion of mTOR Protein/genetics ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
The cytoplasmic microtubule array in Neurospora crassa depends on microtubule-organizing centers at spindle pole bodies and microtubule +end-depending pseudo-MTOCs at septa.
Autorzy:
Ramírez-Cota R; Departamento de Microbiología. Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, B.C., Mexico.
Espino-Vazquez AN; Departamento de Microbiología. Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, B.C., Mexico.
Rodriguez-Vega TC; Departamento de Microbiología. Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, B.C., Mexico.
Macias-Díaz RE; Departamento de Microbiología. Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, B.C., Mexico.
Callejas-Negrete OA; Departamento de Microbiología. Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, B.C., Mexico.
Freitag M; Department of Biochemistry and Biophysics, Center for Genome Research and Biocomputing, Oregon State University, Corvallis, OR, USA.
Fischer R; Department of Microbiology, Institute for Applied Biosciences, Karlsruhe Institute of Technology (KIT), South Campus, Fritz-Haber-Weg 4, Karlsruhe D-76131, Germany.
Roberson RW; School of Life Sciences, Arizona State University, Tempe, AZ, USA.
Mouriño-Pérez RR; Departamento de Microbiología. Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Ensenada, B.C., Mexico. Electronic address: .
Pokaż więcej
Źródło:
Fungal genetics and biology : FG & B [Fungal Genet Biol] 2022 Sep; Vol. 162, pp. 103729. Date of Electronic Publication: 2022 Aug 06.
Typ publikacji:
Journal Article
MeSH Terms:
Carrier Proteins*/metabolism
Fungal Proteins*/metabolism
Microtubule-Associated Proteins*/metabolism
Neurospora crassa*/genetics
Neurospora crassa*/metabolism
Benomyl/metabolism ; Microtubule-Organizing Center/metabolism ; Microtubules/metabolism ; Spindle Pole Bodies/metabolism ; Tubulin/genetics
Czasopismo naukowe
Tytuł:
Suppression of tumor progression by thioredoxin-interacting protein-dependent adenosine 2B receptor degradation in a PLAG-treated Lewis lung carcinoma-1 model of non-small cell lung cancer.
Autorzy:
Kim GT; Enzychem Lifesciences, 10F aT Center 27 Gangnam-daero, Seoul, South Korea.
Kim EY; Enzychem Lifesciences, 10F aT Center 27 Gangnam-daero, Seoul, South Korea.
Shin SH; Enzychem Lifesciences, 10F aT Center 27 Gangnam-daero, Seoul, South Korea.
Lee H; Enzychem Lifesciences, 10F aT Center 27 Gangnam-daero, Seoul, South Korea.
Lee SH; Enzychem Lifesciences, 10F aT Center 27 Gangnam-daero, Seoul, South Korea.
Sohn KY; Enzychem Lifesciences, 10F aT Center 27 Gangnam-daero, Seoul, South Korea.
Kim JW; Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Kwahak-ro, Daejeon, South Korea. Electronic address: .
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2022 Sep; Vol. 31, pp. 100815. Date of Electronic Publication: 2022 Jun 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Lewis Lung*/drug therapy
Carcinoma, Lewis Lung*/metabolism
Carcinoma, Non-Small-Cell Lung*/drug therapy
Carcinoma, Non-Small-Cell Lung*/metabolism
Carrier Proteins*/metabolism
Lung Neoplasms*
Receptors, Purinergic P1*/drug effects
Receptors, Purinergic P1*/metabolism
Thioredoxins*/metabolism
Adenosine/pharmacology ; Animals ; Diglycerides/metabolism ; Diglycerides/pharmacology ; Mice ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
RBM45 is an m A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs.
Autorzy:
Choi SH; Department of Biochemistry, Duke University School of Medicine, Durham NC 27710, USA.
Flamand MN; Department of Biochemistry, Duke University School of Medicine, Durham NC 27710, USA.
Liu B; Department of Biochemistry, Duke University School of Medicine, Durham NC 27710, USA.
Zhu H; Department of Biochemistry, Duke University School of Medicine, Durham NC 27710, USA.
Hu M; Trinity College of Arts and Sciences, Duke University, Durham, NC 27710, USA.
Wang M; Trinity College of Arts and Sciences, Duke University, Durham, NC 27710, USA.
Sewell J; Department of Biochemistry, Duke University School of Medicine, Durham NC 27710, USA.
Holley CL; Department of Medicine (Cardiology Division), Duke University School of Medicine, Durham, NC 27710, USA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.
Al-Hashimi HM; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.
Meyer KD; Department of Biochemistry, Duke University School of Medicine, Durham NC 27710, USA; Department of Neurobiology, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: .
Pokaż więcej
Źródło:
Cell reports [Cell Rep] 2022 Aug 30; Vol. 40 (9), pp. 111293.
Typ publikacji:
Journal Article
MeSH Terms:
Carrier Proteins*/metabolism
RNA-Binding Proteins*/genetics
RNA-Binding Proteins*/metabolism
Protein Binding ; RNA/metabolism ; RNA Splicing/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe

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