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Tytuł :
Endothelial disruptive proinflammatory effects of nicotine and e-cigarette vapor exposures.
Autorzy :
Schweitzer KS; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana;
Chen SX; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana;
Law S; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana;
Van Demark M; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana;
Poirier C; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana;
Justice MJ; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana;
Hubbard WC; Department of Clinical Pharmacology, The Johns Hopkins University, Baltimore, Maryland;
Kim ES; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana;
Lai X; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana;
Wang M; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana;
Kranz WD; Department of Chemistry and Chemical Biology; Indiana University-Purdue University, Indianapolis, Indiana;
Carroll CJ; Department of Chemistry and Chemical Biology; Indiana University-Purdue University, Indianapolis, Indiana;
Ray BD; Department of Physics, Indiana University-Purdue University, Indianapolis, Indiana;
Bittman R; Queens College, City University of New York, Flushing, New York; and.
Goodpaster J; Department of Chemistry and Chemical Biology; Indiana University-Purdue University, Indianapolis, Indiana;
Petrache I; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana; Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana .
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2015 Jul 15; Vol. 309 (2), pp. L175-87. Date of Electronic Publication: 2015 May 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Electronic Nicotine Delivery Systems/*adverse effects
Endothelium, Vascular/*drug effects
Nicotine/*adverse effects
Nicotinic Agonists/*adverse effects
Oxidative Stress/*drug effects
Pneumonia/*pathology
Animals ; Capillary Permeability/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Ceramides/metabolism ; Electric Impedance ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Female ; Gas Chromatography-Mass Spectrometry ; Humans ; Immunoblotting ; Lysophospholipids/metabolism ; Mice ; Mice, Inbred C57BL ; Phosphorylation/drug effects ; Pneumonia/chemically induced ; Pneumonia/metabolism ; Rats ; Signal Transduction/drug effects ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Sphingosine/analogs & derivatives ; Sphingosine/metabolism
Czasopismo naukowe
Tytuł :
ATR phosphorylates SMARCAL1 to prevent replication fork collapse.
Autorzy :
Couch FB; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
Bansbach CE
Driscoll R
Luzwick JW
Glick GG
Bétous R
Carroll CM
Jung SY
Qin J
Cimprich KA
Cortez D
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Źródło :
Genes & development [Genes Dev] 2013 Jul 15; Vol. 27 (14), pp. 1610-23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle Proteins/*metabolism
DNA Helicases/*metabolism
DNA Replication/*physiology
Protein-Serine-Threonine Kinases/*metabolism
Animals ; Ataxia Telangiectasia Mutated Proteins ; Cell Line, Tumor ; Cell Survival/drug effects ; DNA Damage/drug effects ; DNA Helicases/genetics ; DNA Replication/drug effects ; DNA, Single-Stranded/genetics ; Enzyme Activation ; Humans ; Phosphorylation/drug effects ; Protein Binding ; Protein Kinase Inhibitors/pharmacology ; Xenopus
Czasopismo naukowe

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