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Tytuł:
The conserved C-terminal residues of FAM83H are required for the recruitment of casein kinase 1 to the keratin cytoskeleton.
Autorzy:
Kuga T; Laboratory of Analytics for Biomolecules, Faculty of Pharmaceutical Science, Setsunan University, 45-1 Nagaotoge-cho, Hirakata-shi, Osaka, 573-0101, Japan. .
Inoue N; Laboratory of Analytics for Biomolecules, Faculty of Pharmaceutical Science, Setsunan University, 45-1 Nagaotoge-cho, Hirakata-shi, Osaka, 573-0101, Japan.
Sometani K; Laboratory of Analytics for Biomolecules, Faculty of Pharmaceutical Science, Setsunan University, 45-1 Nagaotoge-cho, Hirakata-shi, Osaka, 573-0101, Japan.
Murataka S; Laboratory of Analytics for Biomolecules, Faculty of Pharmaceutical Science, Setsunan University, 45-1 Nagaotoge-cho, Hirakata-shi, Osaka, 573-0101, Japan.
Saraya M; Laboratory of Analytics for Biomolecules, Faculty of Pharmaceutical Science, Setsunan University, 45-1 Nagaotoge-cho, Hirakata-shi, Osaka, 573-0101, Japan.
Sugita R; Laboratory of Analytics for Biomolecules, Faculty of Pharmaceutical Science, Setsunan University, 45-1 Nagaotoge-cho, Hirakata-shi, Osaka, 573-0101, Japan.
Mikami T; Pax Creation Medical Lab., LLC, Iwate, 020-0805, Japan.
Takeda Y; Division of Clinical Pathology, Department of Reconstructive Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University, Iwate, 028-3694, Japan.
Taniguchi M; Laboratory of Analytics for Biomolecules, Faculty of Pharmaceutical Science, Setsunan University, 45-1 Nagaotoge-cho, Hirakata-shi, Osaka, 573-0101, Japan.
Nishida K; Department of Integrative Pharmaceutical Sciences, Faculty of Pharmaceutical Science, Setsunan University, Osaka, 573-0101, Japan.
Yamagishi N; Laboratory of Analytics for Biomolecules, Faculty of Pharmaceutical Science, Setsunan University, 45-1 Nagaotoge-cho, Hirakata-shi, Osaka, 573-0101, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Jul 12; Vol. 12 (1), pp. 11819. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Casein Kinase I*/genetics
Casein Kinase I*/metabolism
Keratins*/genetics
Keratins*/metabolism
Amino Acids/metabolism ; Animals ; Casein Kinases/metabolism ; Cytoskeleton/metabolism ; Microtubules/metabolism ; Mutant Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protein Kinase CK2α', More than a Backup of CK2α.
Autorzy:
Montenarh M; Medical Biochemistry and Molecular Biology, Saarland University, Building 44, 66421 Homburg, Germany.
Götz C; Medical Biochemistry and Molecular Biology, Saarland University, Building 44, 66421 Homburg, Germany.
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Źródło:
Cells [Cells] 2023 Dec 14; Vol. 12 (24). Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Casein Kinase II*/chemistry
Casein Kinase II*/genetics
Casein Kinase II*/metabolism
Humans ; Animals ; Isoenzymes/chemistry ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Holoenzymes/chemistry ; Holoenzymes/genetics ; Holoenzymes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of histidine protonation state on ligand binding at the ATP-binding site of human protein kinase CK2.
Autorzy:
Winiewska-Szajewska M; Institute of Biochemistry and Biophysics PAS, Pawinskiego 5a, 02-106, Warsaw, Poland. .; Division of Biophysics, Institute of Experimental Physics, University of Warsaw, Pasteura 5, 02-089, Warsaw, Poland. .
Paprocki D; Institute of Biochemistry and Biophysics PAS, Pawinskiego 5a, 02-106, Warsaw, Poland.
Marzec E; Institute of Biochemistry and Biophysics PAS, Pawinskiego 5a, 02-106, Warsaw, Poland.
Poznański J; Institute of Biochemistry and Biophysics PAS, Pawinskiego 5a, 02-106, Warsaw, Poland. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 17; Vol. 14 (1), pp. 1463. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
Histidine*/metabolism
Casein Kinase II*/metabolism
Humans ; Protein Binding ; Ligands ; Binding Sites ; Catalytic Domain ; Adenosine Triphosphate/metabolism ; Hydrogen-Ion Concentration
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Casein Kinase 1 Phosphomimetic Mutations Negatively Impact Connexin-43 Gap Junctions in Human Pluripotent Stem Cell-Derived Cardiomyocytes.
Autorzy:
Al-Attar R; McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G 1L7, Canada.
Jargstorf J; McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G 1L7, Canada.
Romagnuolo R; McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G 1L7, Canada.
Jouni M; McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G 1L7, Canada.
Alibhai FJ; McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G 1L7, Canada.
Lampe PD; Translational Research Program, Public Health Sciences and Human Biology Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Solan JL; Translational Research Program, Public Health Sciences and Human Biology Divisions, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Laflamme MA; McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G 1L7, Canada.; Peter Munk Cardiac Centre, University Health Network, Toronto, ON M5G 1L7, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 1L7, Canada.
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Źródło:
Biomolecules [Biomolecules] 2024 Jan 02; Vol. 14 (1). Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinase I*/genetics
Connexin 43*/genetics
Myocytes, Cardiac*
Adult ; Animals ; Humans ; Mice ; Connexins ; Gap Junctions ; Mice, Transgenic ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Exploring the potential of approved drugs for triple-negative breast cancer treatment by targeting casein kinase 2: Insights from computational studies.
Autorzy:
Shoaib TH; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, University of Gezira, Gezira, Sudan.
Ibraheem W; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, University of Gezira, Gezira, Sudan.
Abdelrahman M; Faculty of Pharmacy, Department of Pharmaceutics, University of Gezira, Gezira, Sudan.
Osman W; Faculty of Pharmacy, Department of Pharmacognosy, Prince Sattam Bin Abdulaziz University, Al-kharj, Saudi Arabia.; Faculty of Pharmacy, Department of Pharmacognosy, University of Khartoum, Khartoum, Sudan.
Sherif AE; Faculty of Pharmacy, Department of Pharmacognosy, Prince Sattam Bin Abdulaziz University, Al-kharj, Saudi Arabia.; Faculty of Pharmacy, Department of Pharmacognosy, Mansoura University, Mansoura, Egypt.
Ashour A; Faculty of Pharmacy, Department of Pharmacognosy, Prince Sattam Bin Abdulaziz University, Al-kharj, Saudi Arabia.; Faculty of Pharmacy, Department of Pharmacognosy, Mansoura University, Mansoura, Egypt.
Ibrahim SRM; Department of Chemistry, Preparatory Year Program, Batterjee Medical College, Jeddah, Saudi Arabia.; Faculty of Pharmacy, Department of Pharmacognosy, Assiut University, Assiut, Egypt.
Ghazawi KF; Clinical Pharmacy Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
Miski SF; Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia.
Almadani SA; Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia.
ALsiyud DF; Department of Medical Laboratories-Hematology, King Fahd Armed Forces Hospital, Corniche Road, Andalus, Jeddah, Saudi Arabia.
Mohamed GA; Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
Alzain AA; Faculty of Pharmacy, Department of Pharmaceutical Chemistry, University of Gezira, Gezira, Sudan.
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Źródło:
PloS one [PLoS One] 2023 Aug 14; Vol. 18 (8), pp. e0289887. Date of Electronic Publication: 2023 Aug 14 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Casein Kinase II*/drug effects
Triple Negative Breast Neoplasms*/drug therapy
Antineoplastic Agents*/pharmacology
Female ; Humans ; Drug Approval ; Molecular Docking Simulation ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dual Anta-Inhibitors Targeting Protein Kinase CK1δ and A 2A Adenosine Receptor Useful in Neurodegenerative Disorders.
Autorzy:
Francucci B; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Angeloni S; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Dal Ben D; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Lambertucci C; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Ricciutelli M; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Spinaci A; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Smirnov A; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Volpini R; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Buccioni M; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Marucci G; Medicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 14; Vol. 28 (12). Date of Electronic Publication: 2023 Jun 14.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinase Idelta*
Neurodegenerative Diseases*/drug therapy
Humans ; Up-Regulation ; Receptors, Purinergic P1/metabolism ; Receptor, Adenosine A2A/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Casein Kinase 2 Alpha Inhibition Protects against Sepsis-Induced Acute Kidney Injury.
Autorzy:
Koo JH; Department of Biochemistry and Molecular Biology, Jeonbuk National University Medical School, Jeonju 54896, Republic of Korea.
Yu HC; Department of Biochemistry and Molecular Biology, Jeonbuk National University Medical School, Jeonju 54896, Republic of Korea.
Nam S; Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and Hospital, Jeonju 54896, Republic of Korea.
Kim DC; Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and Hospital, Jeonju 54896, Republic of Korea.
Lee JH; Department of Anesthesiology and Pain Medicine, Jeonbuk National University Medical School and Hospital, Jeonju 54896, Republic of Korea.; Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju 54896, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 06; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinase II*/antagonists & inhibitors
Sepsis*/complications
Acute Kidney Injury*/microbiology
Acute Kidney Injury*/prevention & control
Triazoles*/pharmacology
Triazoles*/therapeutic use
Protein Kinase Inhibitors*/pharmacology
Protein Kinase Inhibitors*/therapeutic use
Animals ; Mice ; Mice, Inbred C57BL ; Disease Models, Animal ; Male
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibition of casein kinase 2 induces cell death in tyrosine kinase inhibitor resistant chronic myelogenous leukemia cells.
Autorzy:
Mitrovský O; Department of Proteomics, Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic.; Faculty of Science, Charles University, Prague, Czech Republic.
Myslivcová D; Department of Proteomics, Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic.
Macháčková-Lopotová T; Department of Proteomics, Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic.
Obr A; Department of Proteomics, Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic.
Čermáková K; Laboratory of PCR Diagnostics of Leukemias, Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic.
Ransdorfová Š; Department of Cytogenetics, Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic.
Březinová J; Department of Cytogenetics, Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic.
Klamová H; Clinical Division, Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic.
Žáčková M; Department of Proteomics, Institute of Hematology and Blood Transfusion, Prague 2, Czech Republic.
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Źródło:
PloS one [PLoS One] 2023 May 04; Vol. 18 (5), pp. e0284876. Date of Electronic Publication: 2023 May 04 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Casein Kinase II*
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy
Humans ; Imatinib Mesylate/pharmacology ; Tyrosine Kinase Inhibitors ; Dasatinib/pharmacology ; Fusion Proteins, bcr-abl/metabolism ; Drug Resistance, Neoplasm ; Apoptosis ; Protein Kinase Inhibitors/pharmacology ; Cell Death
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Casein Kinase 1α as a Novel Factor Affects Thyrotropin Synthesis via PKC/ERK/CREB Signaling.
Autorzy:
Wang B; College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Zhang J; Institute of Reproduction and Metabolism, Yangzhou University, Yangzhou 225009, China.; Joint International Research Laboratory of Agriculture and Agri-Product Safety, The Ministry of Education of China, Yangzhou University, Yangzhou 225009, China.
Zhang D; College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.; Institute of Reproduction and Metabolism, Yangzhou University, Yangzhou 225009, China.
Lu C; College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Liu H; College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Gao Q; Institute of Reproduction and Metabolism, Yangzhou University, Yangzhou 225009, China.
Niu T; College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Yin M; College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Cui S; College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.; Institute of Reproduction and Metabolism, Yangzhou University, Yangzhou 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 11; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinases*/metabolism
Extracellular Signal-Regulated MAP Kinases*/metabolism
Thyrotropin*/metabolism
Animals ; Mice ; Pituitary Gland/metabolism ; Thyrotropin-Releasing Hormone/metabolism ; Thyroxine/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of RAGE and CK2 Expressions in Human Fetal Membranes.
Autorzy:
Coste K; iGReD, Team 'Translational Approach to Epithelial Injury and Repair', UMR6293 CNRS-U1103 INSERM, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.; CHU Clermont-Ferrand, Neonatal Intensive Care Department, F-63000 Clermont-Ferrand, France.
Bruet S; CHU Clermont-Ferrand, Neonatal Intensive Care Department, F-63000 Clermont-Ferrand, France.
Chollat-Namy C; CHU Clermont-Ferrand, Neonatal Intensive Care Department, F-63000 Clermont-Ferrand, France.
Filhol O; INSERM, CEA, UMR Biosanté, U1292, University Grenoble Alpes, F-38000 Grenoble, France.
Cochet C; INSERM, CEA, UMR Biosanté, U1292, University Grenoble Alpes, F-38000 Grenoble, France.
Gallot D; iGReD, Team 'Translational Approach to Epithelial Injury and Repair', UMR6293 CNRS-U1103 INSERM, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.; CHU Clermont-Ferrand, Obstetrics and Gynecology Department, F-63000 Clermont-Ferrand, France.
Marceau G; iGReD, Team 'Translational Approach to Epithelial Injury and Repair', UMR6293 CNRS-U1103 INSERM, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.; CHU Clermont-Ferrand, Biochemistry and Molecular Genetic Department, F-63000 Clermont-Ferrand, France.
Blanchon L; iGReD, Team 'Translational Approach to Epithelial Injury and Repair', UMR6293 CNRS-U1103 INSERM, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.
Sapin V; iGReD, Team 'Translational Approach to Epithelial Injury and Repair', UMR6293 CNRS-U1103 INSERM, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.; CHU Clermont-Ferrand, Biochemistry and Molecular Genetic Department, F-63000 Clermont-Ferrand, France.
Belville C; iGReD, Team 'Translational Approach to Epithelial Injury and Repair', UMR6293 CNRS-U1103 INSERM, Université Clermont Auvergne, F-63000 Clermont-Ferrand, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Feb 17; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinase II*/metabolism
Extraembryonic Membranes*/metabolism
Protein Processing, Post-Translational*
Receptor for Advanced Glycation End Products*/metabolism
Humans ; Phosphorylation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Protein Kinase CK2 Contributes to Glucose Homeostasis by Targeting Fructose-1,6-Bisphosphatase 1.
Autorzy:
Pack M; Medical Biochemistry and Molecular Biology, Saarland University, Building 44, 66421 Homburg, Germany.
Gulde TN; Medical Biochemistry and Molecular Biology, Saarland University, Building 44, 66421 Homburg, Germany.
Völcker MV; Medical Biochemistry and Molecular Biology, Saarland University, Building 44, 66421 Homburg, Germany.
Boewe AS; Institute for Clinical and Experimental Surgery, Saarland University, Building 65, 66421 Homburg, Germany.
Wrublewsky S; Institute for Clinical and Experimental Surgery, Saarland University, Building 65, 66421 Homburg, Germany.
Ampofo E; Institute for Clinical and Experimental Surgery, Saarland University, Building 65, 66421 Homburg, Germany.
Montenarh M; Medical Biochemistry and Molecular Biology, Saarland University, Building 44, 66421 Homburg, Germany.
Götz C; Medical Biochemistry and Molecular Biology, Saarland University, Building 44, 66421 Homburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 27; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 27.
Typ publikacji:
Journal Article
MeSH Terms:
Fructose-Bisphosphatase*/genetics
Fructose-Bisphosphatase*/metabolism
Casein Kinase II*/genetics
Casein Kinase II*/metabolism
Glucose/metabolism ; Gluconeogenesis ; Homeostasis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CKII Control of Axonal Plasticity Is Mediated by Mitochondrial Ca via Mitochondrial NCLX.
Autorzy:
Katoshevski T; Department of Physiology and Cell Biology, Ben Gurion University, Beer-Sheva 8410501, Israel.
Bar L; Department of Physiology & Pharmacology, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Tikochinsky E; Department of Physiology & Pharmacology, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Harel S; Department of Physiology and Cell Biology, Ben Gurion University, Beer-Sheva 8410501, Israel.
Ben-Kasus Nissim T; Department of Physiology and Cell Biology, Ben Gurion University, Beer-Sheva 8410501, Israel.
Bogeski I; Department of Cardiovascular Physiology, Göttingen University, 37073 Göttingen, Germany.
Hershfinkel M; Department of Physiology and Cell Biology, Ben Gurion University, Beer-Sheva 8410501, Israel.
Attali B; Department of Physiology & Pharmacology, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.
Sekler I; Department of Physiology and Cell Biology, Ben Gurion University, Beer-Sheva 8410501, Israel.
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Źródło:
Cells [Cells] 2022 Dec 09; Vol. 11 (24). Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Axon Initial Segment*/metabolism
Casein Kinase II*/genetics
Casein Kinase II*/metabolism
Mitochondria*/metabolism
Neuronal Plasticity*/genetics
Neuronal Plasticity*/physiology
Humans ; Homeostasis ; Neuroblastoma
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
6-(Tetrazol-5-yl)-7-aminoazolo[1,5- a ]pyrimidines as Novel Potent CK2 Inhibitors.
Autorzy:
Urakov GV; Department of Organic and Biomolecular Chemistry, Ural Federal University Named after the First President of Russia B.N. Eltsin, Mira St. 19, 620002 Yekaterinburg, Russia.
Savateev KV; Department of Organic and Biomolecular Chemistry, Ural Federal University Named after the First President of Russia B.N. Eltsin, Mira St. 19, 620002 Yekaterinburg, Russia.
Kotovskaya SK; Department of Organic and Biomolecular Chemistry, Ural Federal University Named after the First President of Russia B.N. Eltsin, Mira St. 19, 620002 Yekaterinburg, Russia.
Rusinov VL; Department of Organic and Biomolecular Chemistry, Ural Federal University Named after the First President of Russia B.N. Eltsin, Mira St. 19, 620002 Yekaterinburg, Russia.
Spasov AA; Scientific Center for Innovative Drugs, Volgograd State Medical University, 400131 Volgograd, Russia.
Babkov DA; Scientific Center for Innovative Drugs, Volgograd State Medical University, 400131 Volgograd, Russia.
Sokolova EV; Scientific Center for Innovative Drugs, Volgograd State Medical University, 400131 Volgograd, Russia.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 08; Vol. 27 (24). Date of Electronic Publication: 2022 Dec 08.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinase II*
Salts*
Drug Design ; Structure-Activity Relationship ; Tetrazoles/pharmacology ; Pyrimidines/pharmacology ; Nitriles ; Sodium ; Molecular Structure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Yeast Protein Asf1 Possesses Modulating Activity towards Protein Kinase CK2.
Autorzy:
Baier A; Department of Animal Physiology and Toxicology, Faculty of Medicine, The John Paul II Catholic University of Lublin, Konstantynów 1i, 20-708 Lublin, Poland.
Szyszka R; Department of Molecular Biology, Faculty of Medicine, The John Paul II Catholic University of Lublin, Konstantynów 1i, 20-708 Lublin, Poland.
Jach ME; Department of Molecular Biology, Faculty of Medicine, The John Paul II Catholic University of Lublin, Konstantynów 1i, 20-708 Lublin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Dec 12; Vol. 23 (24). Date of Electronic Publication: 2022 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinase II*
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Phosphorylation ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Fungal Proteins/metabolism ; Caspases/genetics ; Caspases/metabolism ; Cell Cycle Proteins/metabolism ; Molecular Chaperones/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Catalytic Subunit of Schizosaccharomyces pombe CK2 (Cka1) Negatively Regulates RNA Polymerase II Transcription through Phosphorylation of Positive Cofactor 4 (PC4).
Autorzy:
Rojas DA; Instituto de Ciencias Biomédicas (ICB), Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago 8910132, Chile.
Urbina F; Programa de Biología Celular y Molecular, Instituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380492, Chile.
Solari A; Programa de Biología Celular y Molecular, Instituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380492, Chile.
Maldonado E; Programa de Biología Celular y Molecular, Instituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago 8380492, Chile.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 22; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinase II*/genetics
Casein Kinase II*/metabolism
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
RNA Polymerase II*/metabolism
Schizosaccharomyces*/genetics
Schizosaccharomyces*/metabolism
Schizosaccharomyces pombe Proteins*/genetics
Schizosaccharomyces pombe Proteins*/metabolism
Catalytic Domain ; Cell Extracts ; Phosphorylation ; Serine/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Age-Related Low Bone Mineral Density in C57BL/6 Mice Is Reflective of Aberrant Bone Morphogenetic Protein-2 Signaling Observed in Human Patients Diagnosed with Osteoporosis.
Autorzy:
Halloran D; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
Pandit V; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
MacMurray C; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
Stone V; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
DeGeorge K; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
Eskander M; Delaware Orthopaedic Specialists, Newark, DE 19713, USA.
Root D; Orthopedic Surgery, ChristianaCare Hospital, Wilmington, DE 19801, USA.
McTague S; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.; Orthopedic Surgery, ChristianaCare Hospital, Newark, DE 19716, USA.
Pelkey H; Orthopedic Surgery, ChristianaCare Hospital, Newark, DE 19716, USA.
Nohe A; Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 23; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 23.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinase II*/metabolism
Osteoporosis*/metabolism
Animals ; Bone Morphogenetic Protein 2/genetics ; Bone Morphogenetic Protein 2/metabolism ; Bone Morphogenetic Protein Receptors/metabolism ; Humans ; Mice ; Mice, Inbred C57BL ; Osteoblasts/metabolism ; Osteogenesis/physiology ; Signal Transduction/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Anti-adipogenic and Pro-lipolytic Effects on 3T3-L1 Preadipocytes by CX-4945, an Inhibitor of Casein Kinase 2.
Autorzy:
Yadav AK; Department of Molecular Medicine, College of Medicine, Keimyung University, 1095 Dalgubeoldaero, Dalseo-gu, Daegu 42601, Korea.; The Hormel Institute, University of Minnesota, Austin, MN 55912, USA.
Jang BC; Department of Molecular Medicine, College of Medicine, Keimyung University, 1095 Dalgubeoldaero, Dalseo-gu, Daegu 42601, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 30; Vol. 23 (13). Date of Electronic Publication: 2022 Jun 30.
Typ publikacji:
Journal Article
MeSH Terms:
Adipogenesis*
Casein Kinase II*/antagonists & inhibitors
Casein Kinase II*/metabolism
Naphthyridines*/pharmacology
Phenazines*/pharmacology
3T3-L1 Cells ; AMP-Activated Protein Kinases/metabolism ; Animals ; CCAAT-Enhancer-Binding Protein-alpha/metabolism ; Cell Differentiation/drug effects ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Glycerol/pharmacology ; Humans ; Lipolysis/drug effects ; Mice ; PPAR gamma/metabolism ; Perilipin-1/metabolism ; Sterol Esterase/metabolism
Czasopismo naukowe
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Tytuł:
Light-Control over Casein Kinase 1δ Activity with Photopharmacology: A Clear Case for Arylazopyrazole-Based Inhibitors.
Autorzy:
Schulte AM; Stratingh Institute for Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands.
Kolarski D; Stratingh Institute for Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands.
Sundaram V; Discipline of Biological Engineering, Indian Institute of Technology Gandhinagar, Gandhinagar 382355, India.
Srivastava A; Discipline of Biological Engineering, Indian Institute of Technology Gandhinagar, Gandhinagar 382355, India.
Tama F; Institute of Transformative BioMolecules (WPI-ITbM), Nagoya University, Chikusa, Nagoya 464-8601, Japan.; Department of Physics, Graduate School of Science, Nagoya University, Chikusa, Nagoya 464-8602, Japan.; Computational Structural Biology Unit, RIKEN-Center for Computational Science, Chuo, Kobe 650-0047, Japan.
Feringa BL; Stratingh Institute for Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands.
Szymanski W; Stratingh Institute for Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands.; Department of Radiology, Medical Imaging Center, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 10; Vol. 23 (10). Date of Electronic Publication: 2022 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
Casein Kinase Idelta*/antagonists & inhibitors
Casein Kinase Idelta*/metabolism
Protein Kinase Inhibitors*/pharmacology
Pyrazoles*/pharmacology
Apoptosis/drug effects ; Humans ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 24099

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