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Wyszukujesz frazę ""Caspase 3"" wg kryterium: Temat


Tytuł :
Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis.
Autorzy :
Eskandari E; Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
Eaves CJ; Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, Canada.
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Źródło :
The Journal of cell biology [J Cell Biol] 2022 Jun 06; Vol. 221 (6). Date of Electronic Publication: 2022 May 12.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Carcinogenesis*/genetics
Caspase 3*/physiology
Cell Proliferation*
Cell Survival*/genetics
Apoptosis/genetics ; Humans ; Saccharomyces cerevisiae
Czasopismo naukowe
Tytuł :
Synthesis, Characterization, and In Vivo Study of Some Novel 3,4,5-Trimethoxybenzylidene-hydrazinecarbothioamides and Thiadiazoles as Anti-Apoptotic Caspase-3 Inhibitors.
Autorzy :
Mostafa SM; Chemistry Department, Faculty of Science, Minia University, El-Minia 61519, Egypt.
Aly AA; Chemistry Department, Faculty of Science, Minia University, El-Minia 61519, Egypt.
Bräse S; Institute of Organic Chemistry, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.; Institute of Biological and Chemical Systems (IBCS-FMS), Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, 76131 Karlsruhe, Germany.
Nieger M; Department of Chemistry, University of Helsinki, P.O. Box 55 (A. I. Virtasen aukio I), 00014 Helsinki, Finland.
Abdelhafez SMN; Department of Histology, Faculty of Medicine, Minia University, El-Minia 61519, Egypt.
Abdelzaher WY; Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia 61519, Egypt.
Abdelhafez EMN; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, El-Minia 61519, Egypt.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2022 Mar 31; Vol. 27 (7). Date of Electronic Publication: 2022 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Caspase 3*/metabolism
Caspase Inhibitors*/chemistry
Thiadiazoles*/chemistry
Animals ; Apoptosis ; Cytochromes c/metabolism ; Molecular Docking Simulation ; Rats ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
The Molecular Chaperone CCT Sequesters Gelsolin and Protects it from Cleavage by Caspase-3.
Autorzy :
Cuéllar J; Department of Macromolecular Structures, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, 28049, Spain. Electronic address: .
Vallin J; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan 9C, 40530 Gothenburg, Sweden.
Svanström A; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan 9C, 40530 Gothenburg, Sweden.
Maestro-López M; Department of Macromolecular Structures, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, 28049, Spain.
Bueno-Carrasco MT; Department of Macromolecular Structures, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, 28049, Spain.
Ludlam WG; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA.
Willardson BM; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA.
Valpuesta JM; Department of Macromolecular Structures, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, 28049, Spain.
Grantham J; Department of Chemistry and Molecular Biology, University of Gothenburg, Medicinaregatan 9C, 40530 Gothenburg, Sweden. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2022 Mar 15; Vol. 434 (5), pp. 167399. Date of Electronic Publication: 2021 Dec 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 3*/metabolism
Chaperonin Containing TCP-1*/metabolism
Gelsolin*/chemistry
Gelsolin*/metabolism
Proteolysis*
Actins/metabolism ; Animals ; Cryoelectron Microscopy ; Mice
Czasopismo naukowe
Tytuł :
Effect of l-carnitine supplementation on lead acetate-induced liver cell apoptosis and inflammation: role of caspase-3 and glycogen synthase kinase-3β enzymes.
Autorzy :
Abdel-Emam RA; Department of Pharmacology, Faculty of Medicine, Assiut University, Assiut 71526, Egypt. Electronic address: .
Ali MF; Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2022 Feb 15; Vol. 291, pp. 120277. Date of Electronic Publication: 2021 Dec 31.
Typ publikacji :
Journal Article
MeSH Terms :
Carnitine/*pharmacology
Caspase 3/*metabolism
Glycogen Synthase Kinase 3 beta/*metabolism
Animals ; Anti-Inflammatory Agents/pharmacology ; Antioxidants/pharmacology ; Apoptosis/drug effects ; Carnitine/metabolism ; Caspase 3/physiology ; Dietary Supplements ; Glycogen Synthase Kinase 3 beta/physiology ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Inflammation/metabolism ; Liver/drug effects ; Liver/pathology ; Male ; Organometallic Compounds/adverse effects ; Organometallic Compounds/pharmacology ; Oxidative Stress/drug effects ; Phosphorylation/drug effects ; Rats ; Rats, Wistar ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state.
Autorzy :
Ghazavi F; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
Huysentruyt J; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
De Coninck J; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.; Cancer Research Institute Ghent, B-9052 Ghent, Belgium.
Kourula S; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
Martens S; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
Hassannia B; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
Wartewig T; Center of Molecular and Cellular Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT 06511.
Divert T; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
Roelandt R; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
Popper B; Core Facility Animal Models, Biomedical Center, Ludwig Maximilians University of Munich, D-82152 Planegg-Martinsried, Germany.; Institute of Pathology, Technical University of Munich, D-81675 Munich, Germany.
Hiergeist A; Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, D-93053 Regensburg, Germany.
Tougaard P; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
Vanden Berghe T; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.; Laboratory of Pathophysiology, Faculty of Biomedical Sciences, University of Antwerp, B-2610 Wilrijk, Belgium.
Joossens M; Laboratory of Microbiology, Department of Biochemistry and Microbiology, Faculty of Science, Ghent University, B-9000 Ghent, Belgium.
Berx G; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.; Cancer Research Institute Ghent, B-9052 Ghent, Belgium.
Takahashi N; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
Wahida A; Department of Medicine III, Klinikum rechts der Isar, TUM School of Medicine, Technical University of Munich, D-81675 Munich, Germany.; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, D-85764 Neuherberg, Germany.
Vandenabeele P; VIB-UGent Center for Inflammation Research, B-9052 Ghent, Belgium; .; Department of Biomedical Molecular Biology, Ghent University, B-9052 Ghent, Belgium.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Feb 08; Vol. 119 (6).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Homeostasis*
Signal Transduction*
Caspase 3/*metabolism
Caspase 7/*metabolism
Epithelial Cells/*enzymology
Intestinal Mucosa/*enzymology
Animals ; Caspase 3/genetics ; Caspase 7/genetics ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
An Activatable Hybrid Organic-Inorganic Nanocomposite as Early Evaluation System of Therapy Effect.
Autorzy :
Fu Q; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Feng H; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Su L; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Zhang X; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Liu L; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Fu F; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Yang H; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
Song J; MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Feb 07; Vol. 61 (7), pp. e202112237. Date of Electronic Publication: 2021 Dec 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 3/*chemistry
Nanocomposites/*chemistry
Neoplasms/*radiotherapy
Caspase 3/metabolism ; Humans ; Neoplasms/metabolism ; X-Rays
Czasopismo naukowe
Tytuł :
Yak miR-2285o-3p attenuates hypoxia-induced apoptosis by targeting caspase-3.
Autorzy :
Zhang J; Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Long K; Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Wang J; Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Zhang J; Chongqing Academy of Animal Science, Rongchang, Chongqing, 402460, China.
Jin L; Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Tang Q; Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Li X; Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Ma J; Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Li M; Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Jiang A; Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
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Źródło :
Animal genetics [Anim Genet] 2022 Feb; Vol. 53 (1), pp. 49-57. Date of Electronic Publication: 2021 Nov 22.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*genetics
Caspase 3/*genetics
Cattle/*physiology
Hypoxia/*physiopathology
Animals ; Caspase 3/metabolism ; Cattle/genetics ; MicroRNAs
Czasopismo naukowe
Tytuł :
Gga-miR-29a-3p suppresses avian reovirus-induced apoptosis and viral replication via targeting Caspase-3.
Autorzy :
Zhou L; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Li J; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Haiyilati A; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Li X; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Gao L; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Cao H; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.
Wang Y; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China. Electronic address: .
Zheng SJ; Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, China; College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2022 Jan; Vol. 264, pp. 109294. Date of Electronic Publication: 2021 Nov 24.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/genetics
Caspase 3*/genetics
Caspase 3*/metabolism
MicroRNAs*/metabolism
MicroRNAs*/pharmacology
Orthoreovirus, Avian*/physiology
Virus Replication*/genetics
Animals ; Chickens
Czasopismo naukowe
Tytuł :
Caspase-3/NLRP3 signaling in the mesenchymal stromal niche regulates myeloid-biased hematopoiesis.
Autorzy :
Zhang J; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.
Chen Y; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.
Yin D; Department of Hematology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Feng F; Division of Digestive Surgery, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi, China.
An Q; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.
Liu Z; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.
An N; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.
Xu J; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.
Yi J; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.
Gu S; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China.
Yin W; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China. .
Wang Y; Institute of Neuroscience, Fourth Military Medical University, Xi'an, Shaanxi, China. .
Hu X; Department of Transfusion Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi, China. .
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Źródło :
Stem cell research & therapy [Stem Cell Res Ther] 2021 Nov 20; Vol. 12 (1), pp. 579. Date of Electronic Publication: 2021 Nov 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 3*/genetics
Caspase 3*/metabolism
Hematopoiesis*/genetics
Myeloid Progenitor Cells*/metabolism
NLR Family, Pyrin Domain-Containing 3 Protein*/genetics
Stem Cell Niche*
Animals ; Bone Marrow Cells ; Cell Differentiation ; Hematopoietic Stem Cells/metabolism ; Mice
Czasopismo naukowe
Tytuł :
The role of caspase 3 in the mud crab (Scylla paramamosain) after Vibrio parahaemolyticus infection.
Autorzy :
Cheng CH; Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong 510300, China. Electronic address: .
Liu XZ; Liaoning Ocean and Fisheries Science Research Institute, DaLian, 116023, China.
Ma HL; Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong 510300, China.
Liu GX; Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong 510300, China.
Deng YQ; Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong 510300, China.
Feng J; Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong 510300, China.
Jie YK; Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong 510300, China.
Guo ZX; Key Laboratory of South China Sea Fishery Resources Exploitation & Utilization, Ministry of Agriculture and Rural Affairs, South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, Guangdong 510300, China. Electronic address: .
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2021 Nov; Vol. 118, pp. 213-218. Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Journal Article
MeSH Terms :
Brachyura*/enzymology
Brachyura*/immunology
Brachyura*/microbiology
Caspase 3*/metabolism
Vibrio Infections*/immunology
Vibrio Infections*/veterinary
Vibrio parahaemolyticus*/immunology
Animals ; Arthropod Proteins/metabolism ; Phylogeny
Czasopismo naukowe
Tytuł :
Lobaplatin Induces Pyroptosis in Cervical Cancer Cells via the Caspase-3/GSDME Pathway.
Autorzy :
Chen J; Department of Obstetrics and Gynecology, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, 123 Mochou Rd, Nanjing, Jiangsu 210004, P.R. China.
Ge L; Department of Obstetrics and Gynecology, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, 123 Mochou Rd, Nanjing, Jiangsu 210004, P.R. China.
Shi X; Department of Obstetrics and Gynecology, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, 123 Mochou Rd, Nanjing, Jiangsu 210004, P.R. China.
Liu J; Department of Obstetrics and Gynecology, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, 123 Mochou Rd, Nanjing, Jiangsu 210004, P.R. China.
Ruan H; Department of Obstetrics and Gynecology, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, 123 Mochou Rd, Nanjing, Jiangsu 210004, P.R. China.
Heng D; Department of Obstetrics and Gynecology, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, 123 Mochou Rd, Nanjing, Jiangsu 210004, P.R. China.
Ye C; Department of Obstetrics and Gynecology, Nanjing Maternity and Child Health Care Hospital, Women's Hospital of Nanjing Medical University, 123 Mochou Rd, Nanjing, Jiangsu 210004, P.R. China.
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Źródło :
Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2022; Vol. 22 (11), pp. 2091-2097.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 3*/metabolism
Organoplatinum Compounds*/pharmacology
Pore Forming Cytotoxic Proteins*/metabolism
Pyroptosis*/drug effects
Uterine Cervical Neoplasms*/drug therapy
Cell Line, Tumor ; Cyclobutanes/pharmacology ; Female ; Humans ; Receptors, Estrogen/metabolism
Czasopismo naukowe
Tytuł :
Apoptin induces pyroptosis of colorectal cancer cells via the GSDME-dependent pathway.
Autorzy :
Liu Z; College of Veterinary Medicine, Jilin University, Changchun, 130062, China.; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Li Y; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, 130021, China.
Zhu Y; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, 130021, China.
Li N; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Li W; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Shang C; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Song G; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Li S; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Cong J; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Li T; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Xiu Z; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Lu J; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Ge C; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Yang X; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Li Y; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.
Sun L; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.; Department of Head and Neck Surgery, Tumor Hospital of Jilin Province, Changchun, 130012, China.
Li X; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, 130021, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, 225009, China.
Jin N; College of Veterinary Medicine, Jilin University, Changchun, 130062, China.; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 130122, China.; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, 130021, China.; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, 225009, China.
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Źródło :
International journal of biological sciences [Int J Biol Sci] 2022 Jan 01; Vol. 18 (2), pp. 717-730. Date of Electronic Publication: 2022 Jan 01 (Print Publication: 2022).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pyroptosis*
Caspase 3/*metabolism
Caspase 9/*metabolism
Colorectal Neoplasms/*metabolism
Pore Forming Cytotoxic Proteins/*metabolism
Animals ; Caspase 3/genetics ; Caspase 9/genetics ; Colorectal Neoplasms/pathology ; Cytochromes c/metabolism ; Female ; HCT116 Cells ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Mitochondria/metabolism ; Reactive Oxygen Species/metabolism ; Xenograft Model Antitumor Assays ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł :
Fucoidan Modulated Oxidative Stress and Caspase-3 mRNA Expression Induced by Sulfoxaflor in the Brain of Mice.
Autorzy :
Piner Benli P; Department of Veterinary Pharmacology and Toxicology, Faculty of Ceyhan Veterinary Medicine, Cukurova University, 01330, Adana, Turkey. .
Kaya M; Department of Biotechnology, Institute of Natural and Applied Sciences, Cukurova University, 01330, Adana, Turkey.
Coskun C; Department of Biophysics, Faculty of Medicine, Cukurova University, 01330, Adana, Turkey.
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Źródło :
Neurotoxicity research [Neurotox Res] 2021 Dec; Vol. 39 (6), pp. 1908-1919. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article
MeSH Terms :
Brain/*drug effects
Caspase 3/*metabolism
Neuroprotective Agents/*pharmacology
Oxidative Stress/*drug effects
Polysaccharides/*pharmacology
Pyridines/*adverse effects
Sulfur Compounds/*adverse effects
Animals ; Brain/enzymology ; Brain/metabolism ; Caspase 3/drug effects ; Dose-Response Relationship, Drug ; Glutathione/metabolism ; Male ; Mice ; Transcriptome/drug effects
Czasopismo naukowe
Tytuł :
Deorphanizing Caspase-3 and Caspase-9 Substrates In and Out of Apoptosis with Deep Substrate Profiling.
Autorzy :
Araya LE; Department of Biochemistry, University of Alberta, Edmonton T6G 2H7, Alberta, Canada.
Soni IV; Department of Chemistry, University of Massachusetts, Amherst 01003, Massachusetts, United States.
Hardy JA; Department of Chemistry, University of Massachusetts, Amherst 01003, Massachusetts, United States.
Julien O; Department of Biochemistry, University of Alberta, Edmonton T6G 2H7, Alberta, Canada.
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Źródło :
ACS chemical biology [ACS Chem Biol] 2021 Nov 19; Vol. 16 (11), pp. 2280-2296. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*physiology
Caspase 3/*metabolism
Caspase 9/*metabolism
Proteins/*metabolism
Caspase 3/genetics ; Caspase 9/genetics ; Escherichia coli/metabolism ; Gene Expression Regulation, Enzymologic ; Humans ; Jurkat Cells ; Plasmids ; Proteins/chemistry ; Proteins/genetics ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Cutting Edge: Caspase-8 Is a Linchpin in Caspase-3 and Gasdermin D Activation to Control Cell Death, Cytokine Release, and Host Defense during Influenza A Virus Infection.
Autorzy :
Wang Y; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN; and.
Karki R; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN; and.
Zheng M; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN; and.
Kancharana B; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN; and.
Lee S; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN; and.
Kesavardhana S; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN; and.
Hansen BS; Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN.
Pruett-Miller SM; Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN.
Kanneganti TD; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN; and .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Nov 15; Vol. 207 (10), pp. 2411-2416. Date of Electronic Publication: 2021 Oct 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 3/*immunology
Caspase 8/*immunology
Intracellular Signaling Peptides and Proteins/*immunology
Orthomyxoviridae Infections/*immunology
Phosphate-Binding Proteins/*immunology
Animals ; Caspase 3/metabolism ; Caspase 8/metabolism ; Cell Death ; Cytokines ; Influenza A virus/immunology ; Influenza A virus/metabolism ; Mice ; Orthomyxoviridae Infections/metabolism
Czasopismo naukowe
Tytuł :
Enhanced cancer therapeutic efficiency of NO combined with siRNA by caspase-3 responsive polymers.
Autorzy :
Yan Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Wang CH; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Cui SH; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Zhai L; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Sun J; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Liu XY; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Chen X; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Sun Y; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Qian HG; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Hepato-Pancreato-Biliary Surgery, Peking University Cancer Hospital & Institute, Beijing, China.
Gao X; Institute of Pharmacology and Toxicology of Academy of Military Medical Sciences, Beijing, China.
Tang YD; Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital; Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China.
Zhu YJ; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Shi YJ; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Zhang Q; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Wang JC; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China. Electronic address: .
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Źródło :
Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2021 Nov 10; Vol. 339, pp. 506-520. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 3*
Neoplasms*/drug therapy
Polymers*
Nitric Oxide/*therapeutic use
RNA, Small Interfering/*therapeutic use
Humans
Czasopismo naukowe
Tytuł :
Caspase-3 and gasdermin E detection in peri-implantitis.
Autorzy :
Chen C; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China.
Jiang Z; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China.
Jiang Q; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China.
Dai W; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China.
Shao Q; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China.
Chen Q; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China.
Wang Y; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China. Electronic address: .
Yang G; Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2021 Nov 01; Vol. 1867 (11), pp. 166217. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Caspase 3/*metabolism
Gingiva/*pathology
Mouth Mucosa/*pathology
Peri-Implantitis/*immunology
Receptors, Estrogen/*metabolism
Biopsy ; Case-Control Studies ; Caspase 3/analysis ; Cell Line ; Epithelial Cells ; Gingiva/immunology ; Healthy Volunteers ; Humans ; Mouth Mucosa/immunology ; Peri-Implantitis/pathology ; Pyroptosis/immunology ; Receptors, Estrogen/analysis
Czasopismo naukowe
Tytuł :
Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases.
Autorzy :
Raman V; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.; Ernest Pharmaceuticals, LLC, Hadley, MA, USA.
Van Dessel N; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.; Ernest Pharmaceuticals, LLC, Hadley, MA, USA.
Hall CL; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.; Ernest Pharmaceuticals, LLC, Hadley, MA, USA.
Wetherby VE; Ernest Pharmaceuticals, LLC, Hadley, MA, USA.
Whitney SA; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
Kolewe EL; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
Bloom SMK; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
Sharma A; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA.
Hardy JA; Department of Chemistry, University of Massachusetts, Amherst, Amherst, MA, USA.; Molecular and Cell Biology Program, University of Massachusetts, Amherst, Amherst, MA, USA.; Institute for Applied Life Science, University of Massachusetts, Amherst, Amherst, MA, USA.
Bollen M; Laboratory of Biosignaling & Therapeutics, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Van Eynde A; Laboratory of Biosignaling & Therapeutics, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Forbes NS; Department of Chemical Engineering, University of Massachusetts, Amherst, Amherst, MA, USA. .; Ernest Pharmaceuticals, LLC, Hadley, MA, USA. .; Molecular and Cell Biology Program, University of Massachusetts, Amherst, Amherst, MA, USA. .; Institute for Applied Life Science, University of Massachusetts, Amherst, Amherst, MA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Oct 21; Vol. 12 (1), pp. 6116. Date of Electronic Publication: 2021 Oct 21.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Carcinoma, Hepatocellular/*drug therapy
Caspase 3/*administration & dosage
Drug Delivery Systems/*methods
Liver Neoplasms/*prevention & control
Lung Neoplasms/*drug therapy
Salmonella/*genetics
Animals ; Bacteriolysis ; Carcinoma, Hepatocellular/physiopathology ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Drug Delivery Systems/instrumentation ; Female ; Humans ; Liver Neoplasms/secondary ; Male ; Mice ; Salmonella/physiology ; Salmonella typhimurium
Czasopismo naukowe
Tytuł :
Integrin α5 mediates intrinsic cisplatin resistance in three-dimensional nasopharyngeal carcinoma spheroids via the inhibition of phosphorylated ERK /caspase-3 induced apoptosis.
Autorzy :
Ngaokrajang U; Department of Biochemistry, Kasetsart University, Chatuchak, Bangkok, 10900, Thailand.
Janvilisri T; Department of Biochemistry, Mahidol University, Ratchathewi, Bangkok, 10400, Thailand.
Sae-Ueng U; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, 12120, Thailand.
Prungsak A; Department of Biochemistry, Kasetsart University, Chatuchak, Bangkok, 10900, Thailand.
Kiatwuthinon P; Department of Biochemistry, Kasetsart University, Chatuchak, Bangkok, 10900, Thailand. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2021 Sep 15; Vol. 406 (2), pp. 112765. Date of Electronic Publication: 2021 Aug 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Drug Resistance, Neoplasm*
Caspase 3/*chemistry
Cisplatin/*pharmacology
Integrin alpha5/*metabolism
Mitogen-Activated Protein Kinase 1/*chemistry
Nasopharyngeal Carcinoma/*pathology
Spheroids, Cellular/*pathology
Antineoplastic Agents/pharmacology ; Caspase 3/genetics ; Caspase 3/metabolism ; Cell Culture Techniques ; Cell Cycle Checkpoints ; Humans ; Integrin alpha5/genetics ; Mitogen-Activated Protein Kinase 3/antagonists & inhibitors ; Nasopharyngeal Carcinoma/drug therapy ; Nasopharyngeal Carcinoma/metabolism ; Nasopharyngeal Neoplasms/drug therapy ; Nasopharyngeal Neoplasms/metabolism ; Nasopharyngeal Neoplasms/secondary ; Phosphorylation ; Spheroids, Cellular/drug effects ; Spheroids, Cellular/metabolism
Czasopismo naukowe
Tytuł :
A single-cell analytical approach to quantify activated caspase-3/7 during osteoblast proliferation, differentiation, and apoptosis.
Autorzy :
Killinger M; Department of Bioanalytical Instrumentation, Institute of Analytical Chemistry, Czech Academy of Sciences, 602 00, Brno, Czech Republic.; Department of Chemistry, Faculty of Science, Masaryk University, 602 00, Brno, Czech Republic.
Veselá B; Laboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 602 00, Brno, Czech Republic.
Procházková M; Department of Bioanalytical Instrumentation, Institute of Analytical Chemistry, Czech Academy of Sciences, 602 00, Brno, Czech Republic.; Department of Chemistry, Faculty of Science, Masaryk University, 602 00, Brno, Czech Republic.
Matalová E; Laboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 602 00, Brno, Czech Republic.
Klepárník K; Department of Bioanalytical Instrumentation, Institute of Analytical Chemistry, Czech Academy of Sciences, 602 00, Brno, Czech Republic. .
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Źródło :
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Aug; Vol. 413 (20), pp. 5085-5093. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
Caspase 3/*chemistry
Caspase 3/*metabolism
Caspase 7/*chemistry
Caspase 7/*metabolism
Osteoblasts/*cytology
Animals ; Apoptosis ; Caspase 3/genetics ; Caspase 7/genetics ; Cell Differentiation ; Cell Line ; Cell Proliferation ; Enzyme Activation ; Mice ; Osteoblasts/physiology
Czasopismo naukowe

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