Temat: "Caspase 9" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Caspase-9 inhibition decreases expression of Mmp9 during chondrogenesis.
Autorzy:: Ramesova A; Laboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czech Republic.; Department of Physiology, Faculty of Veterinary Medicine, Veterinary University, Brno, Czech Republic.
Vesela B; Laboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czech Republic.; Department of Physiology, Faculty of Veterinary Medicine, Veterinary University, Brno, Czech Republic.
Svandova E; Laboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czech Republic. .; Department of Physiology, Faculty of Veterinary Medicine, Veterinary University, Brno, Czech Republic. .
Lesot H; Laboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czech Republic.
Matalova E; Laboratory of Odontogenesis and Osteogenesis, Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Brno, Czech Republic.; Department of Physiology, Faculty of Veterinary Medicine, Veterinary University, Brno, Czech Republic.; Pokaż więcej
Źródło:: Histochemistry and cell biology [Histochem Cell Biol] 2022 Apr; Vol. 157 (4), pp. 403-413. Date of Electronic Publication: 2022 Jan 09.
Typ publikacji:: Journal Article
MeSH Terms:: Chondrocytes*
Chondrogenesis*/physiology
Animals ; Caspase 9/genetics ; Caspase 9/metabolism ; Caspase Inhibitors/metabolism ; Caspase Inhibitors/pharmacology ; Cell Differentiation ; Cells, Cultured ; Mice ; Osteogenesis

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Skocz do pozycji: 2.

Tytuł:: Action of Akt Pathway on La-Induced Hippocampal Neuron Apoptosis of Rats in the Growth Stage.
Autorzy:: Wang J; Institute of Molecular Medicine, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.; Department of Nursing, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.
Wu T; Institute of Molecular Medicine, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.; Department of Nursing, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.
Ma L; Institute of Molecular Medicine, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.; Department of Nursing, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.
Guo Y; Institute of Molecular Medicine, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.; Department of Nursing, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.
Huang Y; Institute of Molecular Medicine, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.; Department of Nursing, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China.
Zheng L; Institute of Molecular Medicine, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China. .; Department of Nursing, School of medicine, Eastern Liaoning University, Dandong, 118003, Liaoning, People's Republic of China. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2020 Aug; Vol. 38 (2), pp. 434-446. Date of Electronic Publication: 2020 May 08.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Lanthanum/*toxicity
Memory/*drug effects
Neurons/*drug effects
Proto-Oncogene Proteins c-akt/*drug effects
Animals ; Caspase 3/drug effects ; Caspase 3/metabolism ; Caspase 9/drug effects ; Caspase 9/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Learning/drug effects ; Neurons/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/drug effects ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats ; Rats, Wistar ; Reverse Transcriptase Polymerase Chain Reaction ; bcl-2-Associated X Protein/drug effects ; bcl-2-Associated X Protein/metabolism ; bcl-Associated Death Protein/drug effects ; bcl-Associated Death Protein/metabolism ; bcl-X Protein/drug effects ; bcl-X Protein/metabolism

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Skocz do pozycji: 3.

Tytuł:: TNF-α Mediates the Intrinsic and Extrinsic Pathway in Propofol-Induced Neuronal Apoptosis Via PI3K/Akt Signaling Pathway in Rat Prefrontal Cortical Neurons.
Autorzy:: Deng X; Department of Anesthesiology, Chongqing Cancer Institute, Chongqing, 40030, People's Republic of China.
Chen B; Department of Anesthesiology, Chongqing Cancer Institute, Chongqing, 40030, People's Republic of China.
Wang B; Institute of Life Science, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Zhang J; Department of Anesthesiology, Chongqing Cancer Institute, Chongqing, 40030, People's Republic of China.
Liu H; Department of Anesthesiology, Chongqing Cancer Institute, Chongqing, 40030, People's Republic of China. .; Department of Anesthesiology, Chongqing Cancer Institute, No.181 Hanyu Road, Shapingba District, Chongqing, 400030, People's Republic of China. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2017 Oct; Vol. 32 (3), pp. 409-419. Date of Electronic Publication: 2017 May 24.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Neurons/*drug effects
Prefrontal Cortex/*drug effects
Propofol/*toxicity
Tumor Necrosis Factor-alpha/*metabolism
Animals ; Apoptosis/physiology ; Caspase 8/metabolism ; Caspase 9/metabolism ; Cells, Cultured ; Etanercept/pharmacology ; Hypnotics and Sedatives/toxicity ; Neurons/metabolism ; Neurons/pathology ; Neuroprotective Agents/pharmacology ; Phosphatidylinositol 3-Kinases/metabolism ; Prefrontal Cortex/metabolism ; Prefrontal Cortex/pathology ; Proto-Oncogene Proteins c-akt/metabolism ; Rats, Sprague-Dawley ; Receptors, Purinergic P2X7/metabolism ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/antagonists & inhibitors

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Skocz do pozycji: 4.

Tytuł:: Coenzyme Q10 Prevents Mitochondrial Dysfunction and Facilitates Pharmacological Activity of Atorvastatin in 6-OHDA Induced Dopaminergic Toxicity in Rats.
Autorzy:: Prajapati SK; Neurotherapeutics Laboratory, Department of Pharmaceutics, Indian Institute of Technology (Banaras Hindu University), Varanasi, U.P, 221 005, India.
Garabadu D; Neurotherapeutics Laboratory, Department of Pharmaceutics, Indian Institute of Technology (Banaras Hindu University), Varanasi, U.P, 221 005, India.
Krishnamurthy S; Neurotherapeutics Laboratory, Department of Pharmaceutics, Indian Institute of Technology (Banaras Hindu University), Varanasi, U.P, 221 005, India. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2017 May; Vol. 31 (4), pp. 478-492. Date of Electronic Publication: 2017 Jan 27.
Typ publikacji:: Journal Article
MeSH Terms:: Atorvastatin/*pharmacology
Dopaminergic Neurons/*drug effects
Ubiquinone/*analogs & derivatives
Animals ; Antioxidants/pharmacology ; Caspase 3/metabolism ; Caspase 9/metabolism ; Corpus Striatum/drug effects ; Corpus Striatum/metabolism ; Dopamine/metabolism ; Drug Synergism ; Electron Transport Complex IV/metabolism ; Male ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Mitochondria/metabolism ; Motor Activity/drug effects ; Motor Skills/drug effects ; Oxidative Stress/drug effects ; Oxidopamine ; Pars Compacta/metabolism ; Ubiquinone/pharmacology

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Skocz do pozycji: 5.

Tytuł:: The Fas Ligand/Fas Death Receptor Pathways Contribute to Propofol-Induced Apoptosis and Neuroinflammation in the Brain of Neonatal Rats.
Autorzy:: Milanovic D; Institute for Biological Research, Department of Neurobiology, University of Belgrade, Bulevar Despota Stefana 142, 11060, Belgrade, Serbia. .
Pesic V; Institute for Biological Research, Department of Neurobiology, University of Belgrade, Bulevar Despota Stefana 142, 11060, Belgrade, Serbia.
Loncarevic-Vasiljkovic N; Institute for Biological Research, Department of Neurobiology, University of Belgrade, Bulevar Despota Stefana 142, 11060, Belgrade, Serbia.
Pavkovic Z; Institute for Biological Research, Department of Neurobiology, University of Belgrade, Bulevar Despota Stefana 142, 11060, Belgrade, Serbia.
Popic J; Department of Biochemistry and Goodman Cancer Research Centre, McGill University, Montreal, QC, Canada.
Kanazir S; Institute for Biological Research, Department of Neurobiology, University of Belgrade, Bulevar Despota Stefana 142, 11060, Belgrade, Serbia.
Jevtovic-Todorovic V; Department of Anesthesiology, University of Virginia Health System, Charlottesville, VA, 22908, USA.
Ruzdijic S; Institute for Biological Research, Department of Neurobiology, University of Belgrade, Bulevar Despota Stefana 142, 11060, Belgrade, Serbia.; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2016 Oct; Vol. 30 (3), pp. 434-52. Date of Electronic Publication: 2016 May 17.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis/*drug effects
Brain/*drug effects
Brain/*growth & development
Fas Ligand Protein/*metabolism
Propofol/*toxicity
fas Receptor/*metabolism
Anesthetics, Intravenous/toxicity ; Animals ; Animals, Newborn ; Apoptosis/physiology ; Brain/immunology ; Brain/pathology ; Caspase 1/metabolism ; Caspase 8/metabolism ; Caspase 9/metabolism ; Interleukin-1beta/metabolism ; Male ; Microglia/drug effects ; Microglia/immunology ; Microglia/pathology ; Motor Activity/drug effects ; Motor Activity/physiology ; Neuroimmunomodulation/drug effects ; Neuroimmunomodulation/physiology ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Messenger/metabolism ; Rats, Wistar ; Time Factors

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Skocz do pozycji: 6.

Tytuł:: β-Ecdysterone Protects SH-SY5Y Cells Against 6-Hydroxydopamine-Induced Apoptosis via Mitochondria-Dependent Mechanism: Involvement of p38(MAPK)-p53 Signaling Pathway.
Autorzy:: Pan Z; Center for New Medicine Research, Changchun University of Chinese Medicine, Changchun, 130117, China.
Niu Y; The Institute of Medicine, Qiqihar Medical University, 333 BuKui Street, Jianhua District, Qiqihar, 161006, China.
Liang Y; The Institute of Medicine, Qiqihar Medical University, 333 BuKui Street, Jianhua District, Qiqihar, 161006, China.
Zhang X; The Institute of Medicine, Qiqihar Medical University, 333 BuKui Street, Jianhua District, Qiqihar, 161006, China.
Dong M; The Institute of Medicine, Qiqihar Medical University, 333 BuKui Street, Jianhua District, Qiqihar, 161006, China. .; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2016 Oct; Vol. 30 (3), pp. 453-66. Date of Electronic Publication: 2016 May 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antiparkinson Agents/*pharmacology
Apoptosis/*drug effects
Ecdysterone/*pharmacology
Mitochondria/*drug effects
Oxidopamine/*toxicity
Apoptosis/physiology ; Apoptosis Regulatory Proteins/metabolism ; Caspase 9/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/physiology ; Cytochromes c/metabolism ; Drug Evaluation, Preclinical ; Humans ; MAP Kinase Kinase Kinase 5/metabolism ; MAP Kinase Signaling System/drug effects ; Mitochondria/enzymology ; Proto-Oncogene Proteins/metabolism ; Reactive Oxygen Species/metabolism ; Tumor Suppressor Protein p53/metabolism ; bcl-2-Associated X Protein/metabolism ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism

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Skocz do pozycji: 7.

Tytuł:: Carnosic Acid Affords Mitochondrial Protection in Chlorpyrifos-Treated Sh-Sy5y Cells.
Autorzy:: de Oliveira MR; Department of Chemistry/ICET, Federal University of Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, 2367, Cuiaba, MT, CEP 78060-900, Brazil. .
Peres A; Health Basic Sciences Department, Federal University of Health Sciences of Porto Alegre, RS, Brazil.; Centro de Pesquisa da Pós-Graduação, Centro Universitário Metodista IPA, Porto Alegre, Brazil.
Ferreira GC; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Schuck PF; Laboratório de Erros Inatos do Metabolismo, Unidade Acadêmica de Ciências da Saúde, Programa de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.
Bosco SM; Federal University of Health Sciences of Porto Alegre, Porto Alegre, RS, Brazil.; Pokaż więcej
Źródło:: Neurotoxicity research [Neurotox Res] 2016 Oct; Vol. 30 (3), pp. 367-79. Date of Electronic Publication: 2016 Apr 15.
Typ publikacji:: Journal Article
MeSH Terms:: Abietanes/*pharmacology
Antioxidants/*pharmacology
Chlorpyrifos/*toxicity
Mitochondria/*drug effects
Neuroprotective Agents/*pharmacology
Apoptosis/drug effects ; Apoptosis/physiology ; Caspase 3/metabolism ; Caspase 9/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/physiology ; Cytochromes c/metabolism ; DNA Fragmentation/drug effects ; Drug Evaluation, Preclinical ; Glutathione/metabolism ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/pathology ; Mitochondria/physiology ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphoinositide-3 Kinase Inhibitors ; Proto-Oncogene Proteins c-akt/antagonists & inhibitors ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Small Interfering

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Skocz do pozycji: 8.

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Skocz do pozycji: 9.

Tytuł:: Anti-tumor effect of emodin on gynecological cancer cells.
Autorzy:: Wang Y; Department of Gynaecology, Harbin Medical University Cancer Hospital, 150 Hapin Road, Harbin, 150081, China.
Yu H; Cardiopulmonary Function Room, Harbin Medical University Cancer Hospital, Harbin, China.
Zhang J; Department of Gynaecology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Ge X; Department of General Surgery, The Provincial Hospital of Heilongjiang, Harbin, China.
Gao J; Department of Gynaecology, Harbin Medical University Cancer Hospital, 150 Hapin Road, Harbin, 150081, China.
Zhang Y; Department of Gynaecology, Harbin Medical University Cancer Hospital, 150 Hapin Road, Harbin, 150081, China.
Lou G; Department of Gynaecology, Harbin Medical University Cancer Hospital, 150 Hapin Road, Harbin, 150081, China. .; Pokaż więcej
Źródło:: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2015 Oct; Vol. 38 (5), pp. 353-63. Date of Electronic Publication: 2015 Jul 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Autophagy/*drug effects
Cell Cycle Checkpoints/*drug effects
Emodin/*pharmacology
Apoptosis Regulatory Proteins/metabolism ; Blotting, Western ; Caspase 9/metabolism ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Genital Neoplasms, Female/genetics ; Genital Neoplasms, Female/metabolism ; Genital Neoplasms, Female/pathology ; HeLa Cells ; Humans ; Matrix Metalloproteinase 9/genetics ; Membrane Potential, Mitochondrial/drug effects ; Microtubule-Associated Proteins/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor Receptor-2/metabolism

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Skocz do pozycji: 10.

Tytuł:: Differential regulation of apoptosis in slow and fast twitch muscles of aged female F344BN rats.
Autorzy:: Rice KM; Center for Diagnostic Nanosystems, Marshall University, Room 241D, Robert C. Byrd Biotechnology Science Center Building, 1700 3rd Ave., Huntington, WV, 25755-1090, USA, .
Manne ND
Gadde MK
Paturi S
Arvapalli R
Blough E; Pokaż więcej
Źródło:: Age (Dordrecht, Netherlands) [Age (Dordr)] 2015; Vol. 37 (2), pp. 30. Date of Electronic Publication: 2015 Mar 28.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Aging/*physiology
Apoptosis/*physiology
Apoptosis Regulatory Proteins/*metabolism
Muscle, Skeletal/*physiology
Animals ; Caspase 3/metabolism ; Caspase 9/metabolism ; DNA Fragmentation ; Female ; Muscle, Skeletal/metabolism ; Rats, Inbred F344 ; Reactive Oxygen Species/metabolism