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Tytuł :
Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism.
Autorzy :
Namitz KEW; Department of Biochemistry and Molecular Biology, SUNY-Upstate Medical University, Syracuse, NY, USA.; Department of Chemistry, Pennsylvania State University, University Park, PA, USA.
Zheng T; Departments of Biology and Chemistry, Syracuse University, Syracuse, NY, USA.
Canning AJ; Department of Biochemistry and Molecular Biology, SUNY-Upstate Medical University, Syracuse, NY, USA.
Alicea-Velazquez NL; Department of Biochemistry and Molecular Biology, SUNY-Upstate Medical University, Syracuse, NY, USA.; Department of Chemistry and Biochemistry, Central Connecticut State University, New Britain, CT, USA.
Castañeda CA; Departments of Biology and Chemistry, Syracuse University, Syracuse, NY, USA. .
Cosgrove MS; Department of Biochemistry and Molecular Biology, SUNY-Upstate Medical University, Syracuse, NY, USA. .
Hanes SD; Department of Biochemistry and Molecular Biology, SUNY-Upstate Medical University, Syracuse, NY, USA. .
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Źródło :
Communications biology [Commun Biol] 2021 Mar 25; Vol. 4 (1), pp. 398. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Ubiquitin-Modulated Phase Separation of Shuttle Proteins: Does Condensate Formation Promote Protein Degradation?
Autorzy :
Dao TP; Departments of Biology and Chemistry, Syracuse University, Syracuse, NY, 13244, USA.
Castañeda CA; Departments of Biology and Chemistry, Syracuse University, Syracuse, NY, 13244, USA.; Bioinspired Institute, Syracuse University, Syracuse, NY, 13244, USA.; Interdisciplinary Neuroscience Program, Syracuse University, Syracuse, NY, 13244, USA.
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Źródło :
BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2020 Nov; Vol. 42 (11), pp. e2000036. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Czasopismo naukowe
Tytuł :
COVID-19 in cancer patients: a systematic review.
Autorzy :
Castañeda CA; Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú.; Universidad Científica del Sur, Lima, Perú.
Castillo M; Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú.
Rojas-Vilca JL; Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú.; Universidad Peruana Cayetano Heredia, Lima, Perú.
Fuentes H; Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú.
Gómez HL; Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú.
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Transliterated Title :
COVID-19 en pacientes con cáncer: revisión sistemática.
Źródło :
Revista peruana de medicina experimental y salud publica [Rev Peru Med Exp Salud Publica] 2020 Oct-Dec; Vol. 37 (4), pp. 611-619. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
COVID-19/*epidemiology
Inflammation Mediators/*blood
Neoplasms/*complications
Age Factors ; COVID-19/mortality ; COVID-19/physiopathology ; Comorbidity ; Humans ; Risk Factors ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Structure, dynamics and functions of UBQLNs: at the crossroads of protein quality control machinery.
Autorzy :
Zheng T; Department of Chemistry, Syracuse University, Syracuse, NY 13244, U.S.A.
Yang Y; Department of Chemistry, Syracuse University, Syracuse, NY 13244, U.S.A.
Castañeda CA; Department of Chemistry, Syracuse University, Syracuse, NY 13244, U.S.A.; Departments of Biology and Chemistry, Syracuse University, Syracuse, NY 13244, U.S.A.; Bioinspired Institute, and the Interdisciplinary Neuroscience Program, Syracuse University, Syracuse, NY 13244, U.S.A.
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Źródło :
The Biochemical journal [Biochem J] 2020 Sep 30; Vol. 477 (18), pp. 3471-3497.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Autophagy*
Autophagy-Related Proteins*/chemistry
Autophagy-Related Proteins*/genetics
Autophagy-Related Proteins*/metabolism
DNA Repair*
Endoplasmic Reticulum-Associated Degradation*
Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/metabolism ; Animals ; Frontotemporal Dementia/genetics ; Frontotemporal Dementia/metabolism ; Humans ; Mutation ; Nuclear Proteins/chemistry ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Proteasome Endopeptidase Complex/genetics ; Proteasome Endopeptidase Complex/metabolism ; Protein Domains ; Structure-Activity Relationship ; Ubiquitin/genetics ; Ubiquitin/metabolism
Czasopismo naukowe
Tytuł :
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.
Autorzy :
Kos Z; Department of Pathology, BC Cancer - Vancouver, Vancouver, BC Canada.
Roblin E; 2Department of Biostatistics and Epidemiology, Gustave Roussy, University Paris-Saclay, Villejuif, France.; 3Oncostat U1018, Inserm, University Paris-Saclay, labeled Ligue Contre le Cancer, Villejuif, France.
Kim RS; 4National Surgical Adjuvant Breast and Bowel Project (NSABP)/NRG Oncology, Pittsburgh, PA USA.
Michiels S; 2Department of Biostatistics and Epidemiology, Gustave Roussy, University Paris-Saclay, Villejuif, France.; 3Oncostat U1018, Inserm, University Paris-Saclay, labeled Ligue Contre le Cancer, Villejuif, France.
Gallas BD; 5Division of Imaging, Diagnostics, and Software Reliability (DIDSR); Office of Science and Engineering Laboratories (OSEL); Center for Devices and Radiological Health (CDRH), US Food and Drug Administration (US FDA), Silver Spring, MD USA.
Chen W; 5Division of Imaging, Diagnostics, and Software Reliability (DIDSR); Office of Science and Engineering Laboratories (OSEL); Center for Devices and Radiological Health (CDRH), US Food and Drug Administration (US FDA), Silver Spring, MD USA.
van de Vijver KK; 6Department of Pathology, University Hospital Antwerp, Antwerp, Belgium.; 7Department of Pathology, Ghent University Hospital, Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Goel S; 8The Sir Peter MacCallum Cancer Centre, Melbourne, VIC Australia.; 9Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria Australia.
Adams S; 10Perlmutter Cancer Center, New York University Medical School, New York, NY USA.
Demaria S; 11Departments of Radiation Oncology and Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY USA.
Viale G; 12Department of Pathology, Istituto Europeo di Oncologia, University of Milan, Milan, Italy.
Nielsen TO; 13Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Badve SS; 14Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, USA.
Symmans WF; 15Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX USA.
Sotiriou C; 16Department of Medical Oncology, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Rimm DL; 17Department of Pathology, Yale School of Medicine, New Haven, CT USA.
Hewitt S; 18Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, MD USA.
Denkert C; 19Institute of Pathology, Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg and Philipps-Universität Marburg, Marburg, Germany.
Loibl S; 20German Breast Group, Neu-Isenburg, Germany.
Luen SJ; 9Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria Australia.; 21Division of Research and Cancer Medicine, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC Australia.
Bartlett JMS; 22Ontario Institute for Cancer Research, Toronto, ON Canada.; 23University of Edinburgh Cancer Research Centre, Edinburgh, UK.
Savas P; 9Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria Australia.; 21Division of Research and Cancer Medicine, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC Australia.
Pruneri G; 24Department of Pathology, IRCCS Fondazione Instituto Nazionale Tumori and University of Milan, School of Medicine, Milan, Italy.
Dillon DA; 25Department of Pathology, Brigham and Women's Hospital, Boston, MA USA.; 26Department of Pathology, Dana Farber Cancer Institute, Boston, MA USA.
Cheang MCU; 27Institute of Cancer Research Clinical Trials and Statistics Unit, The Institute of Cancer Research, Surrey, UK.
Tutt A; 28Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.
Hall JA; Vivactiv Ltd, Bellingdon, Bucks, UK.
Kok M; 30Department of Medical Oncology and Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Horlings HM; 6Department of Pathology, University Hospital Antwerp, Antwerp, Belgium.; 31Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Madabhushi A; 32Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH USA.; 33Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH USA.
van der Laak J; 34Computational Pathology Group, Department of Pathology, Radboud University Medical Center, Nijmegen, Netherlands.
Ciompi F; 34Computational Pathology Group, Department of Pathology, Radboud University Medical Center, Nijmegen, Netherlands.
Laenkholm AV; 35Department of Surgical Pathology Zealand University Hospital, Køge, Denmark.
Bellolio E; 36Departamento de Anatomía Patológica, Universidad de La Frontera, Temuco, Chile.
Gruosso T; Forbius, Montreal, QC Canada.
Fox SB; 8The Sir Peter MacCallum Cancer Centre, Melbourne, VIC Australia.; 38Department of Pathology, Peter MacCallum Cancer Centre Department of Pathology, Melbourne, VIC Australia.
Araya JC; 39Department of Pathology, Universidad de la Frontera, Temuco, Chile.
Floris G; 40KU Leuven- Univerisity of Leuven, Department of Imaging and Pathology, Laboratory of Translational Cell & Tissue Research and KU Leuven- University Hospitals Leuven, Department of Pathology, Leuven, Belgium.
Hudeček J; 41Department of Research IT, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Voorwerk L; 42Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Beck AH; 43PathAI, Inc, Boston, MA USA.
Kerner J; 43PathAI, Inc, Boston, MA USA.
Larsimont D; 44Department of Pathology, Jules Bordet Institute, Brussels, Belgium.
Declercq S; Department of Pathology, GZA-ZNA, Antwerp, Belgium.
Van den Eynden G; Department of Pathology, GZA-ZNA, Antwerp, Belgium.
Pusztai L; 46Department of Internal Medicine, Section of Medical Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT USA.
Ehinger A; 47Department of Clinical Genetics and Pathology, Skåne University Hospital, Lund University, Lund, Sweden.
Yang W; 48Department of Pathology, Fudan University Shanghai Cancer Centre, Shanghai, China.
AbdulJabbar K; 49Centre for Evolution and Cancer; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
Yuan Y; 49Centre for Evolution and Cancer; Division of Molecular Pathology, The Institute of Cancer Research, London, UK.
Singh R; 50Icahn School of Medicine at Mt. Sinai, New York, NY 10029 USA.
Hiley C; 51Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.
Bakir MA; 51Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.
Lazar AJ; 52Departments of Pathology, Genomic Medicine, Dermatology, and Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX USA.
Naber S; 53Department of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, USA.
Wienert S; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Charitéplatz 1, 10117 Berlin, Germany.
Castillo M; 55Department of Medical Oncology and Research, Instituto Nacional de Enfermedades Neoplasicas, Lima, 15038 Peru.
Curigliano G; 56University of Milan, Istituto Europeo di Oncologia, IRCCS, Milan, Italy.
Dieci MV; 57Medical Oncology 2, Istituto Oncologico Veneto IOV - IRCCS, Padova, Italy.; 58Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
André F; 59Department of Medical Oncology, Institut Gustave Roussy, Villejuif, France.
Swanton C; 51Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, University College London, London, UK.; 60Francis Crick Institute, Midland Road, London, UK.
Reis-Filho J; 61Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY USA.; 62Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY USA.
Sparano J; 63Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY USA.
Balslev E; 64Department of Pathology, Herlev and Gentofte Hospital, Herlev, Denmark.
Chen IC; 65Department of Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.; 66Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.; 67Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Stovgaard EIS; 64Department of Pathology, Herlev and Gentofte Hospital, Herlev, Denmark.
Pogue-Geile K; 4National Surgical Adjuvant Breast and Bowel Project (NSABP)/NRG Oncology, Pittsburgh, PA USA.
Blenman KRM; 46Department of Internal Medicine, Section of Medical Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT USA.
Penault-Llorca F; 68Centre de Lutte contre le cancer - Centre Jean Perrin, Clermont-Ferrand, France.
Schnitt S; 25Department of Pathology, Brigham and Women's Hospital, Boston, MA USA.
Lakhani SR; 69The University of Queensland Centre for Clinical Research and Pathology Queensland, Brisbane, QLD Australia.
Vincent-Salomon A; Institut Curie, Paris Sciences Lettres Université, Inserm U934, Department of Pathology, Paris, France.
Rojo F; 71Pathology Department, Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD) - CIBERONC, Madrid, Spain.; 72GEICAM-Spanish Breast Cancer Research Group, Madrid, Spain.
Braybrooke JP; 73Nuffield Department of Population Health, University of Oxford, Oxford and Department of Medical Oncology, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Hanna MG; 61Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY USA.
Soler-Monsó MT; 74Department of Pathology, Bellvitge University Hospital, IDIBELL. Breast Unit. Catalan Institut of Oncology. L 'Hospitalet del Llobregat', Barcelona, 08908 Catalonia Spain.
Bethmann D; 75University Hospital Halle (Saale), Institute of Pathology, Halle (Saale), Germany.
Castaneda CA; 55Department of Medical Oncology and Research, Instituto Nacional de Enfermedades Neoplasicas, Lima, 15038 Peru.
Willard-Gallo K; 76Molecular Immunology Unit, Institut Jules Bordet, Universitè Libre de Bruxelles, Brussels, Belgium.
Sharma A; 77Department of Biomedical Informatics, Emory University, Atlanta, GA USA.
Lien HC; 78Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan.
Fineberg S; 79Department of Pathology, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY USA.
Thagaard J; 80DTU Compute, Department of Applied Mathematics, Technical University of Denmark; Visiopharm A/S, Hørsholm, Denmark.
Comerma L; 72GEICAM-Spanish Breast Cancer Research Group, Madrid, Spain.; 81Pathology Department, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain.
Gonzalez-Ericsson P; 82Breast Cancer Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN USA.
Brogi E; 61Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY USA.
Loi S; 9Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria Australia.; 21Division of Research and Cancer Medicine, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC Australia.
Saltz J; 83Biomedical Informatics Department, Stony Brook University, Stony Brook, NY USA.
Klaushen F; 84Institute of Pathology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Cooper L; 85Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL USA.
Amgad M; 86Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA USA.
Moore DA; 87Department of Pathology, UCL Cancer Institute, UCL, London, UK.; 88University College Hospitals NHS Trust, London, UK.
Salgado R; 21Division of Research and Cancer Medicine, Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC Australia.; Department of Pathology, GZA-ZNA, Antwerp, Belgium.
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Corporate Authors :
International Immuno-Oncology Biomarker Working Group
Źródło :
NPJ breast cancer [NPJ Breast Cancer] 2020 May 12; Vol. 6, pp. 17. Date of Electronic Publication: 2020 May 12 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Is Associated with Indigenous American Ancestry in Latin American Women.
Autorzy :
Marker KM; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.; Division of Epidemiology, School of Public Health, University of California Berkeley, Berkeley, California.
Zavala VA; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.
Vidaurre T; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Lott PC; UC Davis Genome Center, University of California, Davis, Davis, California.
Vásquez JN; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Casavilca-Zambrano S; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Calderón M; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Abugattas JE; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Gómez HL; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Fuentes HA; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Picoaga RL; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Cotrina JM; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Neciosup SP; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Castañeda CA; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Morante Z; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Valencia F; Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Torres J; Unidad de Investigación en Enfermedades Infecciosas, Instituto Mexicano del Seguro Social; México City, México.
Echeverry M; Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultades de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia.
Bohórquez ME; Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultades de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia.
Polanco-Echeverry G; UC Davis Genome Center, University of California, Davis, Davis, California.
Estrada-Florez AP; UC Davis Genome Center, University of California, Davis, Davis, California.; Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultades de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Colombia.
Serrano-Gómez SJ; Grupo de Investigación en Biología del Cáncer, Instituto Nacional de Cancerología, Bogotá, Colombia.
Carmona-Valencia JA; Dinamica IPS, Medellín, Colombia.
Alvarado-Cabrero I; Hospital de Oncología de Centro Médico Nacional Siglo XXI, México City, México.
Sanabria-Salas MC; Subdirección de Investigaciones - Instituto Nacional de Cancerología, Bogotá, Colombia.
Velez A; Dinamica IPS, Medellín, Colombia.; Hospital Pablo Tobon Uribe, Medellín, Colombia.
Donado J; Hospital Pablo Tobon Uribe, Medellín, Colombia.
Song S; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.
Cherry D; Department of Medicine, University of California San Diego, San Diego, California.
Tamayo LI; Department of Public Health Sciences, University of Chicago, Chicago, Illinois.
Huntsman S; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.
Hu D; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.
Ruiz-Cordero R; Department of Pathology, University of California, San Francisco, California.
Balassanian R; Department of Pathology, University of California, San Francisco, California.
Ziv E; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.
Zabaleta J; Stanley S. Scott Cancer Center, LSUHSC, New Orleans, Louisiana.; Department of Pediatrics, LSUHSC, New Orleans, Louisiana.
Carvajal-Carmona L
Fejerman L; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, California. .; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California.
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Corporate Authors :
COLUMBUS Consortium
Źródło :
Cancer research [Cancer Res] 2020 May 01; Vol. 80 (9), pp. 1893-1901. Date of Electronic Publication: 2020 Apr 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*chemistry
Breast Neoplasms/*ethnology
Hispanic Americans/*genetics
Receptor, ErbB-2/*analysis
Adult ; African Continental Ancestry Group/ethnology ; African Continental Ancestry Group/statistics & numerical data ; Aged ; Asian Continental Ancestry Group/ethnology ; Asian Continental Ancestry Group/statistics & numerical data ; Breast Neoplasms/genetics ; Colombia/ethnology ; European Continental Ancestry Group/ethnology ; European Continental Ancestry Group/statistics & numerical data ; Female ; Humans ; Indians, North American ; Indians, South American ; Latin America/ethnology ; Linear Models ; Logistic Models ; Mexico/ethnology ; Middle Aged ; Peru/ethnology ; Receptor, ErbB-2/genetics ; Receptors, Estrogen/blood ; Receptors, Progesterone/blood ; United States ; Young Adult
Czasopismo naukowe
Tytuł :
The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.
Autorzy :
Gonzalez-Ericsson PI; Breast Cancer Research Program, Vanderbilt University Medical Center, Nashville, TN, USA.
Stovgaard ES; Department of Pathology, Herlev and Gentofte Hospital, University of Copenhagen, Herlev, Denmark.
Sua LF; Department of Pathology and Laboratory Medicine, Fundación Valle del Lili, and Faculty of Health Sciences, Universidad ICESI, Cali, Colombia.
Reisenbichler E; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
Kos Z; Department of Pathology, BC Cancer Agency, Vancouver, Canada.
Carter JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Michiels S; Biostatistics and Epidemiology Service, Centre de Recherche en Epidémiologie et Santé des Populations, Gustave Roussy, Université Paris-Sud, Villejuif, France.
Le Quesne J; Leicester Cancer Research Centre, University of Leicester, Leicester, UK.; MRC Toxicology Unit, University of Cambridge, Leicester, UK.
Nielsen TO; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Laenkholm AV; Department of Surgical Pathology, Zealand University Hospital, Roskilde, Denmark.
Fox SB; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.
Adam J; Department of Pathology, Gustave Roussy, Grand Paris, France.
Bartlett JM; Ontario Institute for Cancer Research, Toronto, Canada.; Edinburgh Cancer Research Centre, Institute of Genetics and Molecular Medicine, Edinburgh, UK.
Rimm DL; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
Quinn C; Department of Pathology, St Vincent's University Hospital and University College Dublin, Dublin, Ireland.
Peeters D; HistoGeneX NV, Antwerp, Belgium.; AZ Sint-Maarten Hospital, Mechelen, Belgium.
Dieci MV; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.; Medical Oncology 2, Istituto Oncologico Veneto - IRCCS, Padova, Italy.
Vincent-Salomon A; Department of Pathology, Insitut Curie, Paris, France.
Cree I; International Agency for Research on Cancer (IARC), World Health Organization, Lyon, France.
Hida AI; Department of Pathology, Matsuyama Shimin Hospital, Matsuyama, Japan.
Balko JM; Breast Cancer Research Program, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Haynes HR; Department of Cellular Pathology, North Bristol NHS Trust, Bristol, UK.; Translational Health Sciences, University of Bristol, Bristol, UK.
Frahm I; Department of Pathology, Sanatorio Mater Dei, Buenos Aires, Argentina.
Acosta-Haab G; Department of Pathology, Hospital de Oncología Maria Curie, Buenos Aires, Argentina.
Balancin M; Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.
Bellolio E; Department of Pathology, Universidad de La Frontera, Temuco, Chile.
Yang W; Department of Pathology, Fudan University Shanghai Cancer Centre, Shanghai, PR China.
Kirtani P; Department of Histopathology, Manipal Hospitals Dwarka, New Delhi, India.
Sugie T; Breast Surgery, Kansai Medical University Hospital, Hirakata, Japan.
Ehinger A; Department of Clinical Genetics and Pathology, Skane University Hospital, Lund University, Lund, Sweden.
Castaneda CA; Department of Medical Oncology, Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Kok M; Divisions of Medical Oncology, Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
McArthur H; Medical Oncology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Siziopikou K; Department of Pathology, Breast Pathology Section, Northwestern University, Chicago, IL, USA.
Badve S; Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA.
Fineberg S; Department of Pathology, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY, USA.
Gown A; PhenoPath Laboratories, Seattle, WA, USA.
Viale G; Department of Pathology, Istituto Europeo di Oncologia IRCCS, Milan, Italy.; University of Milan, Milan, Italy.
Schnitt SJ; Department of Pathology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Pruneri G; University of Milan, Milan, Italy.; Department of Pathology, IRCCS Fondazione Instituto Nazionale Tumori, Milan, Italy.
Penault-Llorca F; Department of Biology and Pathology, Centre Jean Perrin, Clermont Ferrand, France.; UMR INSERM 1240, Université Clermont Auvergne, Clermont Ferrand, France.
Hewitt S; Experimental Pathology Laboratory, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Thompson EA; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
Allison KH; Department of Pathology, Stanford University, Stanford, CA, USA.
Symmans WF; Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Bellizzi AM; Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Brogi E; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Moore DA; CRUK Lung Cancer Centre of Excellence, UCL Cancer Institute, and Department of Cellular Pathology, UCLH, London, UK.
Larsimont D; Department of Pathology, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Dillon DA; Department of Pathology, Dana-Farber Cancer Institute, Boston, MA, USA.
Lazar A; Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Lien H; Graduate Institute of Pathology, National Taiwan University, Taipei, Taiwan.
Goetz MP; Department of Oncology, Mayo Clinic, Rochester, MN, USA.
Broeckx G; Department of Pathology, University Hospital Antwerp, Edegem, Belgium.
El Bairi K; Cancer Biomarkers Working Group, Faculty of Medicine and Pharmacy, Mohamed Ist University, Oujda, Morocco.
Harbeck N; Breast Center, Department of OB&GYN and CCC (LMU), University of Munich, Munich, Germany.
Cimino-Mathews A; Department of Pathology and Oncology, The Johns Hopkins Hospital, Baltimore, MD, USA.
Sotiriou C; Department of Medical Oncology, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Adams S; Perlmutter Cancer Center, New York University Medical School, New York, NY, USA.
Liu SW; Sichuan Cancer Hospital, Chengdu, PR China.
Loibl S; German Breast Group, Neu-Isenburg, Germany.
Chen IC; Department of Medical Oncology, National Taiwan University Cancer Center, Taipei, Taiwan.
Lakhani SR; The University of Queensland, Centre for Clinical Research, and Pathology Queensland, Royal Brisbane and Women's Hospital, Herston, Australia.
Juco JW; Translational Medicine, Merck & Co, Inc, Kenilworth, NJ, USA.
Denkert C; Institute of Pathology, Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg and Philipps-Universität Marburg, Marburg, Germany.
Blackley EF; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
Demaria S; Department of Radiation Oncology, Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Leon-Ferre R; Department of Oncology, Mayo Clinic, Rochester, MN, USA.
Gluz O; Johanniter GmbH - Evangelisches Krankenhaus Bethesda Mönchengladbach, West German Study Group, Mönchengladbach, Germany.
Zardavas D; Oncology Clinical Development, Bristol-Myers Squibb, Princeton, NJ, USA.
Emancipator K; Translational Medicine, Merck & Co, Inc, Kenilworth, NJ, USA.
Ely S; Translational Medicine, Bristol-Myers Squibb, Princeton, NJ, USA.
Loi S; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Australia.; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Australia.
Salgado R; Division of Research, Peter MacCallum Cancer Centre, Melbourne, Australia.; Department of Pathology, GZA-ZNA Hospitals, Antwerp, Belgium.
Sanders M; Breast Cancer Research Program, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
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Corporate Authors :
International Immuno-Oncology Biomarker Working Group
Źródło :
The Journal of pathology [J Pathol] 2020 Apr; Vol. 250 (5), pp. 667-684. Date of Electronic Publication: 2020 Apr 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
B7-H1 Antigen/*metabolism
Biomarkers, Tumor/*metabolism
Lymphocytes, Tumor-Infiltrating/*pathology
Triple Negative Breast Neoplasms/*pathology
B7-H1 Antigen/immunology ; Biomarkers, Tumor/immunology ; Humans ; Lymphocytes, Tumor-Infiltrating/immunology ; Risk Management ; Triple Negative Breast Neoplasms/immunology
Czasopismo naukowe
Tytuł :
Latin American Study of Hereditary Breast and Ovarian Cancer LACAM : A Genomic Epidemiology Approach.
Autorzy :
Oliver J; Medical Oncology Service, Hospitales Universitarios Regional y Virgen de la Victoria, Institute of Biomedical Research in Malaga, CIMES, University of Málaga, Málaga, Spain.; Laboratorio de Secuenciación, Instituto de Medicina Traslacional e Ingeniería Biomédica, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.; Laboratorio Nacional en Salud, Diagnóstico Molecular y Efecto Ambiental en Enfermedades Crónico-Degenerativas, Facultad de Estudios Superiores Iztacala, Tlalnepantla de Baz, Mexico.
Quezada Urban R; Laboratorio Nacional en Salud, Diagnóstico Molecular y Efecto Ambiental en Enfermedades Crónico-Degenerativas, Facultad de Estudios Superiores Iztacala, Tlalnepantla de Baz, Mexico.; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, UNAM, Tlalnepantla de Baz, Mexico.
Franco Cortés CA; Laboratorio de Secuenciación, Instituto de Medicina Traslacional e Ingeniería Biomédica, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Díaz Velásquez CE; Laboratorio Nacional en Salud, Diagnóstico Molecular y Efecto Ambiental en Enfermedades Crónico-Degenerativas, Facultad de Estudios Superiores Iztacala, Tlalnepantla de Baz, Mexico.
Montealegre Paez AL; Instituto de Nutrición, Genética y Metabolismo, Facultad de Medicina, Universidad El Bosque, Bogota, Colombia.
Pacheco-Orozco RA; Instituto de Nutrición, Genética y Metabolismo, Facultad de Medicina, Universidad El Bosque, Bogota, Colombia.
Castro Rojas C; Instituto de Nutrición, Genética y Metabolismo, Facultad de Medicina, Universidad El Bosque, Bogota, Colombia.
García-Robles R; Instituto de Nutrición, Genética y Metabolismo, Facultad de Medicina, Universidad El Bosque, Bogota, Colombia.
López Rivera JJ; Grupo INPAC, Organización Keralty, Departamento de Genética, Clínica Universitaria Colombia, Bogotá, Colombia.
Gaitán Chaparro S; Grupo INPAC, Organización Keralty, Facultad de Medicina, Fundación Universitaria Sanitas, Bogotá, Colombia.
Gómez AM; Servicio de Genética, Hospital Universitario San Ignacio, Bogotá, Colombia.
Suarez Obando F; Servicio de Genética, Hospital Universitario San Ignacio, Bogotá, Colombia.; Instituto de Genética Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia.
Giraldo G; Clínica Universitaria Bolivariana, Pontificia Universidad Bolivariana, Medellín, Colombia.
Maya MI; Clínica Universitaria Bolivariana, Pontificia Universidad Bolivariana, Medellín, Colombia.
Hurtado-Villa P; Departamento Ciencias Básicas de Salud, Facultad de Ciencias de la Salud, Pontificia Universidad Javeriana Cali, Cali, Colombia.; Centro Médico Imbanaco, Cali, Colombia.
Sanchez AI; Centro Médico Imbanaco, Cali, Colombia.; Departamento Materno Infantil, Facultad de Ciencias de la Salud, Pontificia Universidad Javeriana Cali, Cali, Colombia.
Serrano N; Fundación Cardiovascular de Colombia, Centro de Investigaciones, Floridablanca, Colombia.
Orduz Galvis AI; Fundación Cardiovascular de Colombia, Centro de Investigaciones, Floridablanca, Colombia.
Aruachan S; Departamento de Investigación y Estudios Clínicos, IMAT - Oncomédica S.A., Montería, Colombia.
Nuñez Castillo J; Departamento de Investigación y Estudios Clínicos, IMAT - Oncomédica S.A., Montería, Colombia.
Frecha C; Instituto de Medicina Traslacional e Ingeniería Biomédica, CONICET-Instituto Universitario del Hospital Italiano-Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Riggi C; Servicio de Ginecología, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Jauk F; Laboratorio de Secuenciación, Instituto de Medicina Traslacional e Ingeniería Biomédica, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Gómez García EM; Centro Oncológico Estatal ISSEMyM, Toluca de Lerdo, Mexico.
Carranza CL; INVEGEM, Guatemala, Guatemala.
Zamora V; INVEGEM, Guatemala, Guatemala.
Torres Mejía G; Instituto Nacional de Salud Pública, Cuernavaca, Mexico.
Romieu I; Instituto Nacional de Salud Pública, Cuernavaca, Mexico.; Hubert Department of Global Health, Emory University, Atlanta, GA, United States.
Castañeda CA; Departamento de Oncología Médica, Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Castillo M; Departamento de Investigación, Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru.
Gitler R; Fundación Alma, Ciudad de México, Mexico.
Antoniano A; Fundación Alma, Ciudad de México, Mexico.
Rojas Jiménez E; Laboratorio Nacional en Salud, Diagnóstico Molecular y Efecto Ambiental en Enfermedades Crónico-Degenerativas, Facultad de Estudios Superiores Iztacala, Tlalnepantla de Baz, Mexico.; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, UNAM, Tlalnepantla de Baz, Mexico.
Romero Cruz LE; Laboratorio Nacional en Salud, Diagnóstico Molecular y Efecto Ambiental en Enfermedades Crónico-Degenerativas, Facultad de Estudios Superiores Iztacala, Tlalnepantla de Baz, Mexico.; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, UNAM, Tlalnepantla de Baz, Mexico.
Vallejo Lecuona F; Laboratorio Nacional en Salud, Diagnóstico Molecular y Efecto Ambiental en Enfermedades Crónico-Degenerativas, Facultad de Estudios Superiores Iztacala, Tlalnepantla de Baz, Mexico.; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, UNAM, Tlalnepantla de Baz, Mexico.
Delgado Enciso I; Instituto Estatal de Cancerología de Colima, Colima, Mexico.
Martínez Rizo AB; Laboratorio de Investigación Biomédica, Unidad Académica de Medicina, Universidad Autónoma de Nayarit, Tepic, Mexico.
Flores Carranza A; Instituto Mexicano del Seguro Social, Ciudad de México, Mexico.
Benites Godinez V; Instituto Mexicano del Seguro Social, Ciudad de México, Mexico.
Méndez Catalá CF; Laboratorio Nacional en Salud, Diagnóstico Molecular y Efecto Ambiental en Enfermedades Crónico-Degenerativas, Facultad de Estudios Superiores Iztacala, Tlalnepantla de Baz, Mexico.
Herrera LA; Unidad de Investigación Biomédica en Cáncer, Instituto de Investigaciones Biomédicas-Instituto Nacional de Cancerología, Ciudad de México, Mexico.
Chirino YI; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, UNAM, Tlalnepantla de Baz, Mexico.
Terrazas LI; Laboratorio Nacional en Salud, Diagnóstico Molecular y Efecto Ambiental en Enfermedades Crónico-Degenerativas, Facultad de Estudios Superiores Iztacala, Tlalnepantla de Baz, Mexico.; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, UNAM, Tlalnepantla de Baz, Mexico.
Perdomo S; Instituto de Nutrición, Genética y Metabolismo, Facultad de Medicina, Universidad El Bosque, Bogota, Colombia.; Departamento de Patología, Hospital Universitario Fundación Santa Fe de Bogotá, Bogota, Colombia.
Vaca Paniagua F; Laboratorio Nacional en Salud, Diagnóstico Molecular y Efecto Ambiental en Enfermedades Crónico-Degenerativas, Facultad de Estudios Superiores Iztacala, Tlalnepantla de Baz, Mexico.; Unidad de Biomedicina, Facultad de Estudios Superiores Iztacala, UNAM, Tlalnepantla de Baz, Mexico.; Instituto Nacional de Cancerología, Ciudad de México, Mexico.
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Źródło :
Frontiers in oncology [Front Oncol] 2019 Dec 20; Vol. 9, pp. 1429. Date of Electronic Publication: 2019 Dec 20 (Print Publication: 2019).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Level of tumor-infiltrating lymphocytes and density of infiltrating immune cells in different malignancies.
Autorzy :
Castaneda CA; Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.; Faculty of Health Sciences, Universidad Científica del Sur, Lima 15067, Peru.
Castillo M; Department of Research, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Aliaga K; Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Bernabe LA; Department of Research, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Casavilca S; Department of Pathology, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Sanchez J; Department of Research, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Torres-Cabala CA; Departments of Pathology & Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Gomez HL; Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Mas L; Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Dunstan J; Department of Soft Tissue Surgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Cotrina JM; Department of Soft Tissue Surgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Abugattas J; Department of Soft Tissue Surgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Chavez I; Department of Abdominal Surgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Ruiz E; Department of Abdominal Surgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Montenegro P; Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Rojas V; Department of Chest Surgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Orrego E; Department of Neurosurgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Galvez-Nino M; Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Felix B; Department of Research, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Landa-Baella MP; Department of Research, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Vidaurre T; Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Villa MR; Department of Pathology, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Zevallos R; Department of Pathology, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Taxa L; Department of Pathology, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Guerra H; Department of Pathology, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
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Źródło :
Biomarkers in medicine [Biomark Med] 2019 Dec; Vol. 13 (17), pp. 1481-1491. Date of Electronic Publication: 2019 Oct 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lymphocytes, Tumor-Infiltrating/*cytology
Neoplasms/*blood
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Female ; Humans ; Leukocyte Count ; Macrophages/cytology ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of the Phosphomimetic S39E Mutant.
Autorzy :
Welker Leng KR; Department of Chemistry , University of Michigan , 930 North University Avenue , Ann Arbor , Michigan 48109 , United States.
Castañeda CA; Interdepartmental Program in Chemical Biology , University of Michigan , 210 Washtenaw Avenue, 4008 Life Sciences Institute , Ann Arbor , Michigan 48109 , United States.
Decroos C; Department of Chemistry , University of Pennsylvania , 231 South 34th Street , Philadelphia , Pennsylvania 19104 , United States.
Islam B; School of Pharmacy , University College London , 29-39 Brunswick Square , London WC1N 1AX , U.K.
Haider SM; School of Pharmacy , University College London , 29-39 Brunswick Square , London WC1N 1AX , U.K.
Christianson DW; Department of Chemistry , University of Pennsylvania , 231 South 34th Street , Philadelphia , Pennsylvania 19104 , United States.
Fierke CA; Department of Chemistry , University of Michigan , 930 North University Avenue , Ann Arbor , Michigan 48109 , United States.; Interdepartmental Program in Chemical Biology , University of Michigan , 210 Washtenaw Avenue, 4008 Life Sciences Institute , Ann Arbor , Michigan 48109 , United States.; Department of Chemistry , Texas A&M University , Jack K. Williams Administration Building, Suite 100 , College Station , Texas 77843 , United States.
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Źródło :
Biochemistry [Biochemistry] 2019 Nov 12; Vol. 58 (45), pp. 4480-4493. Date of Electronic Publication: 2019 Nov 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Histone Deacetylases/*chemistry
Repressor Proteins/*chemistry
Crystallography, X-Ray ; Histone Deacetylases/genetics ; Histone Deacetylases/metabolism ; Humans ; Molecular Dynamics Simulation ; Phosphorylation ; Point Mutation ; Protein Conformation ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Helicobacter Pylori Detected in Tap Water of Peruvian Patients with Gastric Cancer.
Autorzy :
Castillo M; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.; Universidad Científica del Sur, Peru.
Bernabe L; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Castaneda CA; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.; Universidad Científica del Sur, Peru.
Chavez I; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Ruiz E; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Barreda F; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Valdivia D; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Suarez N; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Nieves J; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Dias-Neto E; CIPE, A.C.Camargo Cancer Center, São Paulo, Brazil.
Boehnke K; University of Michigan, Ann Arbor, Michigan, USA.
Landa-Baella MP; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Montenegro P; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
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Źródło :
Asian Pacific journal of cancer prevention : APJCP [Asian Pac J Cancer Prev] 2019 Nov 01; Vol. 20 (11), pp. 3193-3196. Date of Electronic Publication: 2019 Nov 01.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Adenocarcinoma/*epidemiology
Helicobacter Infections/*complications
Helicobacter pylori/*isolation & purification
Stomach Neoplasms/*epidemiology
Water Microbiology/*standards
Water Supply/*standards
Adenocarcinoma/microbiology ; Adenocarcinoma/pathology ; Female ; Follow-Up Studies ; Helicobacter Infections/microbiology ; Humans ; Incidence ; Male ; Middle Aged ; Peru/epidemiology ; Prognosis ; Prospective Studies ; Stomach Neoplasms/microbiology ; Stomach Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Role of undifferentiation markers and androgen receptor expression in triple-negative breast cancer.
Autorzy :
Castaneda CA; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.; Universidad Cientifica del Sur, Lima, Peru.
Castillo M; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.; Universidad Cientifica del Sur, Lima, Peru.
Enciso JA; Universidad Cientifica del Sur, Lima, Peru.
Enciso N; Universidad Cientifica del Sur, Lima, Peru.
Bernabe LA; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
Sanchez J; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
Guerra H; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
Chavez C; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
Landa-Baella M; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
De-La-Cruz M; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
Villa-Robles M; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
Tello K; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
Gomez HL; Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima, Peru.
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Źródło :
The breast journal [Breast J] 2019 Nov; Vol. 25 (6), pp. 1316-1319. Date of Electronic Publication: 2019 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Triple Negative Breast Neoplasms*/diagnosis
Triple Negative Breast Neoplasms*/immunology
Triple Negative Breast Neoplasms*/metabolism
Triple Negative Breast Neoplasms*/pathology
Antigens, CD/*analysis
CD8 Antigens/*analysis
Cell Adhesion Molecules, Neuronal/*analysis
Fetal Proteins/*analysis
Lymphocytes, Tumor-Infiltrating/*immunology
Receptors, Androgen/*analysis
Biomarkers, Tumor/analysis ; Cell Adhesion ; Cell Proliferation ; Epithelial-Mesenchymal Transition ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; Prognosis ; Ribonucleoproteins, Small Nucleolar/analysis ; Survival Analysis
Czasopismo naukowe
Tytuł :
Relationship between tumor-associated immune infiltrate and p16 staining over clinicopathological features in acral lentiginous melanoma.
Autorzy :
Castaneda CA; Medical Oncology Department and Research Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru. .; Faculty of Medicine, Universidad Privada San Juan Bautista, 15067, Lima, Peru. .
Castillo M; Medical Oncology Department and Research Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Torres-Cabala C; Departments of Pathology and Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Bernabe LA; Medical Oncology Department and Research Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Casavilca S; Pathology Department, Instituto Nacional de Enfermedades Neoplasicas., Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Villegas V; Medical Oncology Department and Research Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Sanchez J; Medical Oncology Department and Research Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
de la Cruz M; Breast Cancer Surgery Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Dunstan J; Breast Cancer Surgery Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Cotrina JM; Breast Cancer Surgery Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Gomez HL; Medical Oncology Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Chavez C; Medical Oncology Department and Research Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Landa-Baella MP; Medical Oncology Department and Research Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Tello K; Medical Oncology Department and Research Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Felix BF; Medical Oncology Department and Research Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
Abugattas J; Breast Cancer Surgery Department, Instituto Nacional de Enfermedades Neoplasicas, Av. Angamos Este 2520 Surquillo, 15038, Lima, Peru.
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Źródło :
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2019 Sep; Vol. 21 (9), pp. 1127-1134. Date of Electronic Publication: 2019 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*analysis
Cyclin-Dependent Kinase Inhibitor p16/*metabolism
Lentigo/*pathology
Lymphocytes, Tumor-Infiltrating/*immunology
Melanoma/*pathology
Skin Neoplasms/*pathology
Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Lentigo/immunology ; Lentigo/metabolism ; Male ; Melanoma/immunology ; Melanoma/metabolism ; Middle Aged ; Prognosis ; Skin Neoplasms/immunology ; Skin Neoplasms/metabolism ; Survival Rate
SCR Disease Name :
Melanoma, Cutaneous Malignant
Czasopismo naukowe
Tytuł :
Phase separation in biology and disease-a symposium report.
Autorzy :
Cable J; Science Writer, New York, New York.
Brangwynne C; Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey.
Seydoux G; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Cowburn D; Departments of Biochemistry and Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, New York.
Pappu RV; Department of Biomedical Engineering, Center for Science and Engineering of Living Systems, McKelvey School of Engineering, St. Louis, Missouri.
Castañeda CA; Departments of Biology and Chemistry, Program in Neuroscience, Syracuse University, Syracuse, New York.
Berchowitz LE; Departments of Genetics and Development, Columbia University, New York, New York.
Chen Z; University of Texas Southwestern Medical Center, Dallas, Texas.
Jonikas M; Department of Molecular Biology, Princeton University, Princeton, New Jersey.
Dernburg A; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California.
Mittag T; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Fawzi NL; Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, Rhode Island.
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Źródło :
Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2019 Sep; Vol. 1452 (1), pp. 3-11. Date of Electronic Publication: 2019 Jun 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Macromolecular Substances*
Cytoplasm/*physiology
Organelles/*physiology
Humans
Czasopismo naukowe
Tytuł :
Prevalence of Helicobacter pylori Infection, Its Virulent Genotypes, and Epstein-Barr Virus in Peruvian Patients With Chronic Gastritis and Gastric Cancer.
Autorzy :
Castaneda CA; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Castillo M; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Chavez I; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Barreda F; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Suarez N; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Nieves J; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Bernabe LA; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Valdivia D; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Ruiz E; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Dias-Neto E; A.C. Camargo Cancer Center, São Paulo, Brazil.
Landa-Baella MP; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Bazan Y; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Rengifo CA; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Montenegro P; Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
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Źródło :
Journal of global oncology [J Glob Oncol] 2019 Sep; Vol. 5, pp. 1-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epstein-Barr Virus Infections/*epidemiology
Gastritis/*complications
Helicobacter pylori/*pathogenicity
Stomach Neoplasms/*complications
Chronic Disease ; Female ; Genotype ; Humans ; Male ; Middle Aged ; Peru ; Prevalence
Czasopismo naukowe
Tytuł :
Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.
Autorzy :
Saura C; Vall d'Hebrón University Hospital, Vall d'Hebrón Institute of Oncology, Barcelona, Spain; SOLTI Breast Cancer Research Group, Barcelona, Spain. Electronic address: .
Hlauschek D; Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria.
Oliveira M; Vall d'Hebrón University Hospital, Vall d'Hebrón Institute of Oncology, Barcelona, Spain; SOLTI Breast Cancer Research Group, Barcelona, Spain.
Zardavas D; Bristol-Myers Squibb Company, Lawrence, NJ, USA.
Jallitsch-Halper A; Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria.
de la Peña L; SOLTI Breast Cancer Research Group, Barcelona, Spain.
Nuciforo P; Vall d'Hebrón University Hospital, Vall d'Hebrón Institute of Oncology, Barcelona, Spain; SOLTI Breast Cancer Research Group, Barcelona, Spain.
Ballestrero A; University of Genoa - Istituto di Ricovero e Cura a Carattere Scientifico, Ospedale Policlinico San Martino, Genova; Gruppo Oncologico Italiano di Ricerca Clinica, Genova, Italy.
Dubsky P; Medical University of Vienna, Vienna, Austria; Hirslanden Klinik St Anna, Breast Centre, Lucerne, Switzerland.
Lombard JM; Breast Cancer Trials Australia New Zealand, University of Newcastle, Newcastle, NSW, Australia.
Vuylsteke P; European Organisation for Research and Treatment of Cancer, Breast Cancer Group, CHU Namur, Université Catholique de Louvain, Ottignies-Nouvain-la-Neuve, Belgium.
Castaneda CA; Grupo de Estudios Clinicos Oncologicos Peruano, Lima, Perú.
Colleoni M; Division of Medical Senology, European Institute of Oncology, Istituto di Ricovero e Cura a Carattere Scientifico and International Breast Cancer Study Group, Milan, Italy.
Santos Borges G; Centro de Novos Tratamentos Itajaí, Itajaí, Brazil.
Ciruelos E; SOLTI Breast Cancer Research Group, Barcelona, Spain; Hospital Universitario 12 de Octubre, Madrid, Spain.
Fornier M; Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, NY, USA.
Boer K; Szent Margit Hospital, Budapest, Hungary.
Bardia A; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Wilson TR; Genentech Inc, South San Francisco, CA, USA.
Stout TJ; Genentech Inc, South San Francisco, CA, USA.
Hsu JY; Genentech Inc, South San Francisco, CA, USA.
Shi Y; Genentech Inc, South San Francisco, CA, USA.
Piccart M; Breast International Group, Brussels, Belgium; Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
Gnant M; Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria; Medical University of Vienna, Vienna, Austria.
Baselga J; AstraZeneca, Gaithersburg, Maryland, USA.
de Azambuja E; Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
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Źródło :
The Lancet. Oncology [Lancet Oncol] 2019 Sep; Vol. 20 (9), pp. 1226-1238. Date of Electronic Publication: 2019 Aug 08.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms/*drug therapy
Class I Phosphatidylinositol 3-Kinases/*genetics
Imidazoles/*administration & dosage
Letrozole/*administration & dosage
Oxazepines/*administration & dosage
Aged ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Biomarkers, Tumor ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Disease-Free Survival ; Double-Blind Method ; Estrogen Receptor alpha/genetics ; Female ; Humans ; Imidazoles/adverse effects ; Letrozole/adverse effects ; Middle Aged ; Neoadjuvant Therapy ; Neoplasm Staging ; Oxazepines/adverse effects ; Postmenopause ; Receptor, ErbB-2/genetics ; Treatment Outcome
Czasopismo naukowe
Tytuł :
ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner.
Autorzy :
Dao TP; Departments of Biology and Chemistry, Syracuse University, Syracuse, NY 13244, USA.
Martyniak B; Department of Chemistry, Syracuse University, Syracuse, NY 13244, USA.
Canning AJ; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Lei Y; Departments of Biology and Chemistry, Syracuse University, Syracuse, NY 13244, USA.
Colicino EG; Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA; Department of Biology, Syracuse University, Syracuse, NY 13244, USA.
Cosgrove MS; Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Hehnly H; Department of Biology, Syracuse University, Syracuse, NY 13244, USA.
Castañeda CA; Departments of Biology and Chemistry, Syracuse University, Syracuse, NY 13244, USA; Interdisciplinary Neuroscience Program, Syracuse University, Syracuse, NY 13244, USA. Electronic address: .
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Źródło :
Structure (London, England : 1993) [Structure] 2019 Jun 04; Vol. 27 (6), pp. 937-951.e5. Date of Electronic Publication: 2019 Apr 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Mutation*
Phase Transition*
Protein Multimerization*
Adaptor Proteins, Signal Transducing/*chemistry
Amino Acids/*chemistry
Amyotrophic Lateral Sclerosis/*genetics
Autophagy-Related Proteins/*chemistry
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Amino Acids/genetics ; Amino Acids/metabolism ; Autophagy-Related Proteins/genetics ; Autophagy-Related Proteins/metabolism ; Humans ; Protein Aggregates ; Protein Aggregation, Pathological ; Stress, Physiological/genetics ; Ubiquitins/genetics ; Ubiquitins/metabolism
Czasopismo naukowe
Tytuł :
Single Amino Acid Substitutions in Stickers, but Not Spacers, Substantially Alter UBQLN2 Phase Transitions and Dense Phase Material Properties.
Autorzy :
Yang Y
Jones HB
Dao TP
Castañeda CA
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Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2019 May 02; Vol. 123 (17), pp. 3618-3629. Date of Electronic Publication: 2019 Apr 19.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Adaptor Proteins, Signal Transducing/*chemistry
Autophagy-Related Proteins/*chemistry
Adaptor Proteins, Signal Transducing/genetics ; Amino Acid Substitution ; Autophagy-Related Proteins/genetics ; Humans ; Models, Molecular ; Mutation ; Particle Size ; Phase Transition ; Surface Properties ; Temperature
Czasopismo naukowe
Tytuł :
Kemp Eliminases of the AlleyCat Family Possess High Substrate Promiscuity.
Autorzy :
Caselle EA; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
Yoon JH; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
Bhattacharya S; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
Rempillo JJL; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
Lengyel Z; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
D'Souza A; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
Moroz YS; Department of Chemistry, Taras Shevchenko National University of Kyiv, 64 Volodymyrska St., Kyiv 01601, Ukraine.
Tolbert PL; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
Volkov AN; VIB Centre for Structural Biology, Vlaams Instituut voor Biotechnologie (VIB), Pleinlaan 2, Brussels 1050, Belgium.; Jean Jeener NMR Cetre, Vrije Universiteit Brussel (VUB), Pleinlaan 2, Brussels 1050, Belgium.
Forconi M; Department of Chemistry and Biochemistry, College of Charleston, 66 George St. Charleston, SC 29424, USA.
Castañeda CA; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
Makhlynets OV; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
Korendovych IV; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, NY 13244, USA.
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Źródło :
ChemCatChem [ChemCatChem] 2019 Mar 06; Vol. 11 (5), pp. 1425-1430. Date of Electronic Publication: 2019 Jan 15.
Typ publikacji :
Journal Article
Czasopismo naukowe

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