Temat: "Catalytic Domain" - OpacWWW

Skocz do pozycji: 61.

Tytuł:: Histidine Protonation and Conformational Switching in Diphtheria Toxin Translocation Domain.
Autorzy:: Rodnin MV; Department of Biochemistry and Molecular Biology, University of Kansas School of Medicine, Kansas City, KS 66160, USA.
Vasques-Montes V; Department of Biochemistry and Molecular Biology, University of Kansas School of Medicine, Kansas City, KS 66160, USA.
Kyrychenko A; Department of Biochemistry and Molecular Biology, University of Kansas School of Medicine, Kansas City, KS 66160, USA.; Institute of Chemistry and School of Chemistry, V. N. Karazin Kharkiv National University, 61022 Kharkiv, Ukraine.
Oliveira NFB; Institute of Biosystems and Integrative Sciences, University of Lisbon, 1749-016 Lisbon, Portugal.
Kashipathy MM; Protein Structure and X-ray Crystallography Laboratory, University of Kansas, Lawrence, KS 66047, USA.
Battaile KP; NYX, New York Structural Biology Center, Upton, NY 10027, USA.
Douglas J; COBRE Bio-NMR Laboratory, University of Kansas, Lawrence, KS 66045, USA.
Lovell S; Protein Structure and X-ray Crystallography Laboratory, University of Kansas, Lawrence, KS 66047, USA.
Machuqueiro M; Institute of Biosystems and Integrative Sciences, University of Lisbon, 1749-016 Lisbon, Portugal.
Ladokhin AS; Department of Biochemistry and Molecular Biology, University of Kansas School of Medicine, Kansas City, KS 66160, USA.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2023 Jun 25; Vol. 15 (7). Date of Electronic Publication: 2023 Jun 25.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Diphtheria Toxin*/chemistry
Histidine*/chemistry
Molecular Dynamics Simulation ; Catalytic Domain ; Protein Transport ; Hydrogen-Ion Concentration ; Protein Conformation

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Skocz do pozycji: 62.

Tytuł:: Enzyme-substrate hybrid β-sheet controls geometry and water access to the γ-secretase active site.
Autorzy:: Chen SY; Center of Functional Protein Assemblies, Technical University of Munich, Garching, Germany.
Feilen LP; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Chávez-Gutiérrez L; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; Department of Neurosciences, Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Leuven, Belgium.
Steiner H; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Biomedical Center (BMC), Division of Metabolic Biochemistry, Faculty of Medicine, LMU Munich, Germany.
Zacharias M; Center of Functional Protein Assemblies, Technical University of Munich, Garching, Germany. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2023 Jun 24; Vol. 6 (1), pp. 670. Date of Electronic Publication: 2023 Jun 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amyloid Precursor Protein Secretases*/genetics
Amyloid Precursor Protein Secretases*/metabolism
Amyloid beta-Protein Precursor*/genetics
Amyloid beta-Protein Precursor*/metabolism
Catalytic Domain ; Protein Conformation, beta-Strand ; Water Supply

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Skocz do pozycji: 63.

Tytuł:: Identification of protein phosphatase 4 catalytic subunit as a Wnt promoting factor in pan-cancer and Xenopus early embryogenesis.
Autorzy:: Wang Y; Laboratory of Developmental Biology, Department of Life Sciences, Pohang University of Science and Technology, Pohang, 37673, Korea.
Han W; Laboratory of Developmental Biology, Department of Life Sciences, Pohang University of Science and Technology, Pohang, 37673, Korea.; Department of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Yun S; Laboratory of Developmental Biology, Department of Life Sciences, Pohang University of Science and Technology, Pohang, 37673, Korea.
Han J; Laboratory of Developmental Biology, Department of Life Sciences, Pohang University of Science and Technology, Pohang, 37673, Korea. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jun 23; Vol. 13 (1), pp. 10240. Date of Electronic Publication: 2023 Jun 23.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Wnt Proteins*/metabolism
Neoplasms*/genetics
Animals ; Humans ; Xenopus laevis/genetics ; Xenopus laevis/metabolism ; Xenopus Proteins/genetics ; Xenopus Proteins/metabolism ; Catalytic Domain ; Embryonic Development/genetics ; Gene Expression Regulation, Developmental

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Skocz do pozycji: 64.

Tytuł:: New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class.
Autorzy:: Selezneva AI; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois, United States of America.
Harding LNM; Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America.
Gutka HJ; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois, United States of America.
Movahedzadeh F; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois, United States of America.; Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America.
Abad-Zapatero C; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois, United States of America.; Center for Biomolecular Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Jun 23; Vol. 18 (6), pp. e0274723. Date of Electronic Publication: 2023 Jun 23 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Fructose-Bisphosphatase*/metabolism
Francisella tularensis*/metabolism
Catalysis ; Catalytic Domain ; Fructose/metabolism ; Crystallography, X-Ray

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Skocz do pozycji: 65.

Tytuł:: Virtual Screening Strategy and In Vitro Tests to Identify New Inhibitors of the Immunoproteasome.
Autorzy:: Culletta G; Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università degli Studi di Palermo, Via Archirafi 32, 90123 Palermo, Italy.; Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università di Messina, Viale Annunziata, 98168 Messina, Italy.
Tutone M; Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università degli Studi di Palermo, Via Archirafi 32, 90123 Palermo, Italy.
Ettari R; Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università di Messina, Viale Annunziata, 98168 Messina, Italy.
Perricone U; Drug Discovery Unit, Fondazione Ri.MED, 90133 Palermo, Italy.
Di Chio C; Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università di Messina, Viale Annunziata, 98168 Messina, Italy.
Almerico AM; Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università degli Studi di Palermo, Via Archirafi 32, 90123 Palermo, Italy.
Zappalà M; Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche ed Ambientali, Università di Messina, Viale Annunziata, 98168 Messina, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 22; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:: Journal Article
MeSH Terms:: Proteasome Inhibitors*/pharmacology
Proteasome Inhibitors*/chemistry
Autoimmune Diseases*
Humans ; Catalytic Domain ; Phagocytosis ; In Vitro Techniques ; Proteasome Endopeptidase Complex/metabolism

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Skocz do pozycji: 66.

Tytuł:: Revealing the Combined Effect of Active Sites and Intra-Particle Diffusion on Adsorption Mechanism of Methylene Blue on Activated Red-Pulp Pomelo Peel Biochar.
Autorzy:: Wei F; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Jin S; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Yao C; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Wang T; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Zhu S; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Ma Y; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Qiao H; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Shan L; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Wang R; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Lian X; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Tong X; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Li Y; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Zhao Q; College of Science, Civil Aviation University of China (CAUC), Tianjin 300300, China.
Song W; Laboratory of Molecular Nanostructure and Nanotechnology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 May 29; Vol. 28 (11). Date of Electronic Publication: 2023 May 29.
Typ publikacji:: Journal Article
MeSH Terms:: Methylene Blue*/chemistry
Water Pollutants, Chemical*
Adsorption ; Catalytic Domain ; Hydrogen-Ion Concentration ; Charcoal ; Kinetics ; Thermodynamics

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Skocz do pozycji: 67.

Tytuł:: Virtual Screening Combined with Enzymatic Assays to Guide the Discovery of Novel SIRT2 Inhibitors.
Autorzy:: Scarano N; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.
Abbotto E; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.
Musumeci F; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.
Salis A; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.
Brullo C; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.
Fossa P; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.
Schenone S; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.
Bruzzone S; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
Cichero E; Department of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 27; Vol. 24 (11). Date of Electronic Publication: 2023 May 27.
Typ publikacji:: Journal Article
MeSH Terms:: Sirtuin 2*/antagonists & inhibitors
Sirtuin 2*/chemistry
Catalytic Domain ; Small Molecule Libraries ; Protein Conformation ; Molecular Docking Simulation

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Skocz do pozycji: 68.

Tytuł:: Effects of Phosphorylation on the Activity, Inhibition and Stability of Carbonic Anhydrases.
Autorzy:: Huang X; School of Chemistry, University of New South Wales, Sydney, NSW 2052, Australia.
Winter D; School of Chemistry, University of New South Wales, Sydney, NSW 2052, Australia.
Glover DJ; School of Biotechnology & Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
Supuran CT; Neurofarba Department, Sezione di Scienze Farmaceutiche, Universita degli Studi di Firenze, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.
Donald WA; School of Chemistry, University of New South Wales, Sydney, NSW 2052, Australia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 25; Vol. 24 (11). Date of Electronic Publication: 2023 May 25.
Typ publikacji:: Journal Article
MeSH Terms:: Carbonic Anhydrases*/metabolism
Humans ; Carbonic Anhydrase II ; Phosphorylation ; Catalytic Domain ; Carbonic Anhydrase Inhibitors/chemistry ; Carbonic Anhydrase IX/metabolism

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Skocz do pozycji: 69.

Tytuł:: NatB Catalytic Subunit Depletion Disrupts DNA Replication Initiation Leading to Senescence in MEFs.
Autorzy:: Elurbide J; Division of Gene Therapy and Regulation of Gene Expression, Centre for Applied Medical Research CIMA, University of Navarra, 31008 Pamplona, Spain.
Carte B; Division of Gene Therapy and Regulation of Gene Expression, Centre for Applied Medical Research CIMA, University of Navarra, 31008 Pamplona, Spain.
Guedes J; Division of Gene Therapy and Regulation of Gene Expression, Centre for Applied Medical Research CIMA, University of Navarra, 31008 Pamplona, Spain.; Department of Biology, Centre of Molecular and Environmental Biology (CBMA/UM), University of Minho, 4710-057 Braga, Portugal.
Aldabe R; Division of Gene Therapy and Regulation of Gene Expression, Centre for Applied Medical Research CIMA, University of Navarra, 31008 Pamplona, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 13; Vol. 24 (10). Date of Electronic Publication: 2023 May 13.
Typ publikacji:: Journal Article
MeSH Terms:: Saccharomyces cerevisiae Proteins*/metabolism
Animals ; Humans ; Catalytic Domain ; Saccharomyces cerevisiae/metabolism ; Protein Processing, Post-Translational ; DNA Replication ; Acetylation ; Acetyltransferases/metabolism ; Mammals/metabolism

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Skocz do pozycji: 70.

Tytuł:: Expression of RNA polymerase I catalytic core is influenced by RPA12.
Autorzy:: Ford BL; Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.; Department of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Wei T; Department of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Liu H; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Scull CE; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Najmi SM; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Pitts S; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Fan W; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Schneider DA; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Laiho M; Department of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 May 11; Vol. 18 (5), pp. e0285660. Date of Electronic Publication: 2023 May 11 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Chromatin*
RNA Polymerase I*/genetics
RNA Polymerase I*/metabolism
Humans ; Catalytic Domain ; RNA Polymerase II/metabolism ; Transcription, Genetic ; Neoplasms/genetics ; Neoplasms/metabolism

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Skocz do pozycji: 71.

Tytuł:: The structure of POMGNT2 provides new insights into the mechanism to determine the functional O-mannosylation site on α-dystroglycan.
Autorzy:: Imae R; Molecular Glycobiology, Research Team for Mechanism of Aging, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Itabashi-ku, Japan.
Kuwabara N; High Energy Accelerator Research Organization (KEK), Institute of Materials Structure Science, Structural Biology Research Center, Tsukuba, Japan.
Manya H; Molecular Glycobiology, Research Team for Mechanism of Aging, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Itabashi-ku, Japan.
Tanaka T; Laboratory of Glyco-organic Chemistry, The Noguchi Institute, Itabashi-ku, Japan.
Tsuyuguchi M; High Energy Accelerator Research Organization (KEK), Institute of Materials Structure Science, Structural Biology Research Center, Tsukuba, Japan.
Mizuno M; Laboratory of Glyco-organic Chemistry, The Noguchi Institute, Itabashi-ku, Japan.
Endo T; Molecular Glycobiology, Research Team for Mechanism of Aging, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Itabashi-ku, Japan.
Kato R; High Energy Accelerator Research Organization (KEK), Institute of Materials Structure Science, Structural Biology Research Center, Tsukuba, Japan.; Pokaż więcej
Źródło:: Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2021 Jul; Vol. 26 (7), pp. 485-494. Date of Electronic Publication: 2021 May 20.
Typ publikacji:: Journal Article
MeSH Terms:: Catalytic Domain*
Glycosyltransferases/*chemistry
Dystroglycans/metabolism ; Glycosyltransferases/metabolism ; Humans ; Mannose/metabolism ; Protein Binding

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Skocz do pozycji: 72.

Tytuł:: The PI-3-Kinase P110α Catalytic Subunit of T Lymphocytes Modulates Collagen-Induced Arthritis.
Autorzy:: Montes-Casado M; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
Ojeda G; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
Criado G; Grupo de Enfermedades Inflamatorias y Autoinmunes, Instituto de Investigación Hospital 12 de Octubre (i+12), 28041 Madrid, Spain.
Rojo JM; Centro de Investigaciones Biológicas Margarita Salas, Departamento de Biomedicina Molecular, Consejo Superior de Investigaciones Científicas (CSIC), 28040 Madrid, Spain.
Portolés P; Centro Nacional de Microbiología, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.; Presidencia, Consejo Superior de Investigaciones Científicas (CSIC), 28006 Madrid, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 15; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 15.
Typ publikacji:: Journal Article
MeSH Terms:: Catalytic Domain*
Arthritis, Experimental/*enzymology
Arthritis, Experimental/*pathology
Class Ia Phosphatidylinositol 3-Kinase/*chemistry
Class Ia Phosphatidylinositol 3-Kinase/*metabolism
T-Lymphocytes/*enzymology
Animals ; Antibodies/blood ; Arthritis, Experimental/blood ; Arthritis, Experimental/immunology ; Biomarkers/metabolism ; Cell Proliferation ; Class Ia Phosphatidylinositol 3-Kinase/genetics ; Disease Models, Animal ; Gene Deletion ; Immunity ; Inducible T-Cell Co-Stimulator Protein/metabolism ; Interleukin-6/blood ; Lymph Nodes/pathology ; Mice, Inbred C57BL ; Signal Transduction ; Mice

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Skocz do pozycji: 73.

Tytuł:: X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.
Autorzy:: Günther S; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany. .
Reinke PYA; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Fernández-García Y; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Str. 74, 20359 Hamburg, Germany.
Lieske J; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Lane TJ; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Ginn HM; Diamond Light Source Ltd., Diamond House, Harwell Science and Innovation Campus, Didcot, OX11 0DE, UK.
Koua FHM; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Ehrt C; Universität Hamburg, Center for Bioinformatics, Bundesstr. 43, 20146 Hamburg, Germany.
Ewert W; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Oberthuer D; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Yefanov O; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Meier S; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Institut für Nanostruktur- und Festkörperphysik, Luruper Chaussee 149, 22761 Hamburg, Germany.
Lorenzen K; European XFEL GmbH, Holzkoppel 4, 22869 Schenefeld, Germany.
Krichel B; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Martinistr. 52, 20251 Hamburg, Germany.
Kopicki JD; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Martinistr. 52, 20251 Hamburg, Germany.
Gelisio L; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Brehm W; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Dunkel I; Max Planck Institute for Molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany.
Seychell B; Universität Hamburg, Department of Chemistry, Institute of Physical Chemistry, Grindelallee 117, 20146 Hamburg, Germany.
Gieseler H; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Institut für Nanostruktur- und Festkörperphysik, Luruper Chaussee 149, 22761 Hamburg, Germany.
Norton-Baker B; Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761 Hamburg, Germany.; Department of Chemistry, UC Irvine, Irvine, CA 92697-2025, USA.
Escudero-Pérez B; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Str. 74, 20359 Hamburg, Germany.
Domaracky M; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Saouane S; Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
Tolstikova A; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
White TA; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Hänle A; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Groessler M; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Fleckenstein H; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Trost F; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Galchenkova M; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Gevorkov Y; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.; Vision Systems, Hamburg University of Technology, 21071 Hamburg, Germany.
Li C; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Awel S; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Peck A; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Barthelmess M; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Schlünzen F; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Lourdu Xavier P; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.; Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761 Hamburg, Germany.
Werner N; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.
Andaleeb H; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.
Ullah N; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.
Falke S; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.
Srinivasan V; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.
França BA; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.
Schwinzer M; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.
Brognaro H; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.
Rogers C; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Institut für Nanostruktur- und Festkörperphysik, Luruper Chaussee 149, 22761 Hamburg, Germany.
Melo D; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Institut für Nanostruktur- und Festkörperphysik, Luruper Chaussee 149, 22761 Hamburg, Germany.
Zaitseva-Doyle JJ; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Institut für Nanostruktur- und Festkörperphysik, Luruper Chaussee 149, 22761 Hamburg, Germany.
Knoska J; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Peña-Murillo GE; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Mashhour AR; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Hennicke V; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Fischer P; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Hakanpää J; Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
Meyer J; Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607, Hamburg, Germany.
Gribbon P; Fraunhofer Institute for Translational Medicine and Pharmacology and Fraunhofer Cluster of Excellence for Immune Mediated Diseases, Schnackenburgallee 114, 22525 Hamburg, Germany.
Ellinger B; Fraunhofer Institute for Translational Medicine and Pharmacology and Fraunhofer Cluster of Excellence for Immune Mediated Diseases, Schnackenburgallee 114, 22525 Hamburg, Germany.
Kuzikov M; Fraunhofer Institute for Translational Medicine and Pharmacology and Fraunhofer Cluster of Excellence for Immune Mediated Diseases, Schnackenburgallee 114, 22525 Hamburg, Germany.
Wolf M; Fraunhofer Institute for Translational Medicine and Pharmacology and Fraunhofer Cluster of Excellence for Immune Mediated Diseases, Schnackenburgallee 114, 22525 Hamburg, Germany.
Beccari AR; Dompé Farmaceutici SpA, 67100 L'Aquila, Italy.
Bourenkov G; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
von Stetten D; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
Pompidor G; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
Bento I; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
Panneerselvam S; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
Karpics I; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
Schneider TR; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
Garcia-Alai MM; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
Niebling S; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
Günther C; EMBL Outstation Hamburg, c/o DESY, Notkestr. 85, 22607 Hamburg, Germany.
Schmidt C; European XFEL GmbH, Holzkoppel 4, 22869 Schenefeld, Germany.
Schubert R; European XFEL GmbH, Holzkoppel 4, 22869 Schenefeld, Germany.
Han H; European XFEL GmbH, Holzkoppel 4, 22869 Schenefeld, Germany.
Boger J; Institute of Molecular Medicine, University of Lübeck, 23562 Lübeck, Germany.
Monteiro DCF; Hauptmann Woodward Medical Research Institute, 700 Ellicott Street, Buffalo, NY 14203, USA.
Zhang L; Institute of Molecular Medicine, University of Lübeck, 23562 Lübeck, Germany.; German Center for Infection Research, Hamburg-Lübeck-Borstel-Riems Site, University of Lübeck, 23562 Lübeck, Germany.
Sun X; Institute of Molecular Medicine, University of Lübeck, 23562 Lübeck, Germany.; German Center for Infection Research, Hamburg-Lübeck-Borstel-Riems Site, University of Lübeck, 23562 Lübeck, Germany.
Pletzer-Zelgert J; Universität Hamburg, Center for Bioinformatics, Bundesstr. 43, 20146 Hamburg, Germany.
Wollenhaupt J; Helmholtz Zentrum Berlin, Macromolecular Crystallography, Albert-Einstein-Str. 15, 12489 Berlin, Germany.
Feiler CG; Helmholtz Zentrum Berlin, Macromolecular Crystallography, Albert-Einstein-Str. 15, 12489 Berlin, Germany.
Weiss MS; Helmholtz Zentrum Berlin, Macromolecular Crystallography, Albert-Einstein-Str. 15, 12489 Berlin, Germany.
Schulz EC; Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761 Hamburg, Germany.
Mehrabi P; Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761 Hamburg, Germany.
Karničar K; Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.; Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins, Jamova 39, 1000 Ljubljana, Slovenia.
Usenik A; Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.; Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins, Jamova 39, 1000 Ljubljana, Slovenia.
Loboda J; Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.
Tidow H; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.
Chari A; Research Group for Structural Biochemistry and Mechanisms, Department of Structural Dynamics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
Hilgenfeld R; Institute of Molecular Medicine, University of Lübeck, 23562 Lübeck, Germany.; German Center for Infection Research, Hamburg-Lübeck-Borstel-Riems Site, University of Lübeck, 23562 Lübeck, Germany.
Uetrecht C; Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Martinistr. 52, 20251 Hamburg, Germany.
Cox R; Institute for Organic Chemistry and BMWZ, Leibniz University of Hannover, Schneiderberg 38, 30167 Hannover, Germany.
Zaliani A; Fraunhofer Institute for Translational Medicine and Pharmacology and Fraunhofer Cluster of Excellence for Immune Mediated Diseases, Schnackenburgallee 114, 22525 Hamburg, Germany.
Beck T; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Department of Chemistry, Institute of Physical Chemistry, Grindelallee 117, 20146 Hamburg, Germany.
Rarey M; Universität Hamburg, Center for Bioinformatics, Bundesstr. 43, 20146 Hamburg, Germany.
Günther S; Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Str. 74, 20359 Hamburg, Germany.
Turk D; Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.; Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins, Jamova 39, 1000 Ljubljana, Slovenia.
Hinrichs W; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.; Universität Greifswald, Institute of Biochemistry, Felix-Hausdorff-Str. 4, 17489 Greifswald, Germany.
Chapman HN; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Department of Physics, Luruper Chaussee 149, 22761 Hamburg, Germany.
Pearson AR; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Institut für Nanostruktur- und Festkörperphysik, Luruper Chaussee 149, 22761 Hamburg, Germany.
Betzel C; Hamburg Centre for Ultrafast Imaging, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg, Germany.; Universität Hamburg, Department of Chemistry, Institute of Biochemistry and Molecular Biology and Laboratory for Structural Biology of Infection and Inflammation, c/o DESY, 22607 Hamburg, Germany.
Meents A; Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany. .; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2021 May 07; Vol. 372 (6542), pp. 642-646. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Allosteric Site*
Catalytic Domain*
Drug Development*
Antiviral Agents/*chemistry
Coronavirus 3C Proteases/*antagonists & inhibitors
Coronavirus 3C Proteases/*chemistry
Protease Inhibitors/*chemistry
SARS-CoV-2/*enzymology
Animals ; Antiviral Agents/pharmacology ; Chlorocebus aethiops ; Crystallography, X-Ray ; Drug Evaluation, Preclinical ; Protease Inhibitors/pharmacology ; SARS-CoV-2/drug effects ; Vero Cells ; Virus Replication/drug effects

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Skocz do pozycji: 74.

Tytuł:: Boronic Acids as Prospective Inhibitors of Metallo-β-Lactamases: Efficient Chemical Reaction in the Enzymatic Active Site Revealed by Molecular Modeling.
Autorzy:: Krivitskaya AV; Bach Institute of Biochemistry, Federal Research Centre 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, 119071 Moscow, Russia.
Khrenova MG; Bach Institute of Biochemistry, Federal Research Centre 'Fundamentals of Biotechnology' of the Russian Academy of Sciences, 119071 Moscow, Russia.; Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Apr 02; Vol. 26 (7). Date of Electronic Publication: 2021 Apr 02.
Typ publikacji:: Journal Article
MeSH Terms:: Catalytic Domain*
Models, Molecular*
Boronic Acids/*pharmacology
beta-Lactamase Inhibitors/*pharmacology
beta-Lactamases/*chemistry
beta-Lactamases/*metabolism
Boronic Acids/chemistry ; Imipenem/chemistry ; Imipenem/pharmacology ; Inhibitory Concentration 50 ; Solutions ; Thermodynamics ; Water/chemistry

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Skocz do pozycji: 75.

Tytuł:: Protonation Equilibrium in the Active Site of the Photoactive Yellow Protein.
Autorzy:: Campomanes P; Department of Biology, University of Fribourg, Chemin du Musée 10, 1700 Fribourg, Switzerland.
Vanni S; Department of Biology, University of Fribourg, Chemin du Musée 10, 1700 Fribourg, Switzerland.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Apr 02; Vol. 26 (7). Date of Electronic Publication: 2021 Apr 02.
Typ publikacji:: Journal Article
MeSH Terms:: Catalytic Domain*
Protons*
Bacterial Proteins/*chemistry
Photoreceptors, Microbial/*chemistry
Electrons ; Hydrogen Bonding ; Molecular Dynamics Simulation ; Thermodynamics

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Skocz do pozycji: 76.

Tytuł:: Plant protein phosphatases: What do we know about their mechanism of action?
Autorzy:: Bheri M; Department of Plant Molecular Biology, University of Delhi South Campus, New Delhi, India.
Mahiwal S; Department of Plant Molecular Biology, University of Delhi South Campus, New Delhi, India.
Sanyal SK; Department of Plant Molecular Biology, University of Delhi South Campus, New Delhi, India.
Pandey GK; Department of Plant Molecular Biology, University of Delhi South Campus, New Delhi, India.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2021 Feb; Vol. 288 (3), pp. 756-785. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Catalytic Domain*
Protein Domains*
Signal Transduction*
Phosphoprotein Phosphatases/*metabolism
Plant Proteins/*metabolism
Biocatalysis ; Models, Molecular ; Phosphoprotein Phosphatases/chemistry ; Phosphoprotein Phosphatases/classification ; Phosphorylation ; Plant Proteins/chemistry ; Protein Subunits/chemistry ; Protein Subunits/metabolism ; Substrate Specificity

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Skocz do pozycji: 77.

Tytuł:: Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus .
Autorzy:: Mirabile S; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.; Foundation Prof. Antonio Imbesi, University of Messina, Piazza Pugliatti 1, I-98122 Messina, Italy.
Ielo L; Department of Chemistry, University of Turin, Via P. Giuria 7, 10125 Torino, Italy.
Lombardo L; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
Ricci F; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
Gitto R; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
Germanò MP; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.
Pace V; Department of Chemistry, University of Turin, Via P. Giuria 7, 10125 Torino, Italy.
De Luca L; Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres 31, I-98166 Messina, Italy.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 27; Vol. 24 (9). Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:: Journal Article
MeSH Terms:: Monophenol Monooxygenase*/metabolism
Agaricus*/chemistry
Melanins/pharmacology ; Catalytic Domain ; Enzyme Inhibitors/chemistry ; Molecular Docking Simulation
SCR Organism:: Agaricus bisporus

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Skocz do pozycji: 78.

Tytuł:: Molecular Dynamics Simulations Reveal the Conformational Transition of GH33 Sialidases.
Autorzy:: Cao X; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-Based Medicine, Shandong University, Qingdao 266237, China.
Yang X; State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Xiao M; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-Based Medicine, Shandong University, Qingdao 266237, China.; State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Jiang X; National Glycoengineering Research Center, Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology, NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-Based Medicine, Shandong University, Qingdao 266237, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 06; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 06.
Typ publikacji:: Journal Article
MeSH Terms:: Neuraminidase*/metabolism
Glycoside Hydrolases*
Humans ; Molecular Dynamics Simulation ; Catalytic Domain ; Catalysis

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Skocz do pozycji: 79.

Tytuł:: Structural and functional characterization of the catalytic domain of a cell-wall anchored bacterial lytic polysaccharide monooxygenase from Streptomyces coelicolor.
Autorzy:: Votvik AK; Faculty of Chemistry, Biotechnology, and Food Science, The Norwegian University of Life Sciences (NMBU), 1432, Ås, Norway.
Røhr ÅK; Faculty of Chemistry, Biotechnology, and Food Science, The Norwegian University of Life Sciences (NMBU), 1432, Ås, Norway.
Bissaro B; Faculty of Chemistry, Biotechnology, and Food Science, The Norwegian University of Life Sciences (NMBU), 1432, Ås, Norway.; INRAE, Aix Marseille University, UMR1163 Biodiversité et Biotechnologie Fongiques, 13009, Marseille, France.
Stepnov AA; Faculty of Chemistry, Biotechnology, and Food Science, The Norwegian University of Life Sciences (NMBU), 1432, Ås, Norway.
Sørlie M; Faculty of Chemistry, Biotechnology, and Food Science, The Norwegian University of Life Sciences (NMBU), 1432, Ås, Norway.
Eijsink VGH; Faculty of Chemistry, Biotechnology, and Food Science, The Norwegian University of Life Sciences (NMBU), 1432, Ås, Norway.
Forsberg Z; Faculty of Chemistry, Biotechnology, and Food Science, The Norwegian University of Life Sciences (NMBU), 1432, Ås, Norway. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Apr 01; Vol. 13 (1), pp. 5345. Date of Electronic Publication: 2023 Apr 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mixed Function Oxygenases*/metabolism
Streptomyces coelicolor*/metabolism
Catalytic Domain ; Phylogeny ; Cellulose ; Chitin/chemistry ; Polysaccharides, Bacterial ; Cell Wall/metabolism ; Polysaccharides

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Skocz do pozycji: 80.

Tytuł:: Counterintuitive structural and functional effects due to naturally occurring mutations targeting the active site of the disease-associated NQO1 enzyme.
Autorzy:: Pacheco-García JL; Departamento de Química Física, Universidad de Granada, Spain.
Anoz-Carbonell E; Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Ciencias, Instituto de Biocomputación y Física de Sistemas Complejos (BIFI) (GBsC-CSIC Joint Unit), Universidad de Zaragoza, Spain.
Loginov DS; Institute of Microbiology - BioCeV, Academy of Sciences of the Czech Republic, Vestec, Czech Republic.
Kavan D; Institute of Microbiology - BioCeV, Academy of Sciences of the Czech Republic, Vestec, Czech Republic.
Salido E; Center for Rare Diseases (CIBERER), Hospital Universitario de Canarias, Universidad de la Laguna, Tenerife, Spain.
Man P; Institute of Microbiology - BioCeV, Academy of Sciences of the Czech Republic, Vestec, Czech Republic.
Medina M; Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Ciencias, Instituto de Biocomputación y Física de Sistemas Complejos (BIFI) (GBsC-CSIC Joint Unit), Universidad de Zaragoza, Spain.
Pey AL; Departamento de Química Física, Unidad de Excelencia en Química Aplicada a Biomedicina y Medioambiente e Instituto de Biotecnología, Universidad de Granada, Spain.; Pokaż więcej
Źródło:: The FEBS journal [FEBS J] 2023 Apr; Vol. 290 (7), pp. 1855-1873. Date of Electronic Publication: 2022 Nov 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Proteins*/chemistry
Mutation, Missense*
Humans ; Catalytic Domain/genetics ; Mutation ; Molecular Biology ; Computational Biology ; NAD(P)H Dehydrogenase (Quinone)/genetics ; NAD(P)H Dehydrogenase (Quinone)/metabolism

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