Autor: "Cayabyab FS" - OpacWWW

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Tytuł:: Adenosine A1 receptor ligands bind to α-synuclein: implications for α-synuclein misfolding and α-synucleinopathy in Parkinson's disease.
Autorzy:: Jakova E; Department of Surgery, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Moutaoufik MT; Department of Chemistry and Biochemistry, Faculty of Science, University of Regina, Regina, SK, Canada.
Lee JS; Department of Biochemistry, Microbiology and Immunology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Babu M; Department of Chemistry and Biochemistry, Faculty of Science, University of Regina, Regina, SK, Canada.
Cayabyab FS; Department of Surgery, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada. frank.cayabyab@usask.ca.; Pokaż więcej
Źródło:: Translational neurodegeneration [Transl Neurodegener] 2022 Feb 10; Vol. 11 (1), pp. 9. Date of Electronic Publication: 2022 Feb 10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Parkinson Disease*/drug therapy
Parkinson Disease*/metabolism
Synucleinopathies*
Animals ; Dopaminergic Neurons/metabolism ; Ligands ; Molecular Docking Simulation ; Rats ; Rats, Sprague-Dawley ; Receptor, Adenosine A1/metabolism ; alpha-Synuclein/metabolism

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Tytuł:: Adenosine A1 and A2A Receptors in the Brain: Current Research and Their Role in Neurodegeneration.
Autorzy:: Stockwell J; Department of Surgery, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada. .
Jakova E; Department of Surgery, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada. .
Cayabyab FS; Department of Surgery, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada. frank.cayabyab@usask.ca.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2017 Apr 23; Vol. 22 (4). Date of Electronic Publication: 2017 Apr 23.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Brain/*metabolism
Neurodegenerative Diseases/*metabolism
Receptor, Adenosine A1/*physiology
Receptor, Adenosine A2A/*physiology
Animals ; Brain/pathology ; Humans ; Neurodegenerative Diseases/drug therapy ; Neuroprotective Agents/pharmacology ; Purinergic Agonists/pharmacology ; Purinergic Antagonists/pharmacology ; Receptor Cross-Talk

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Tytuł:: Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis.
Autorzy:: Lv YC; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.; Laboratory of Clinical Anatomy, University of South China, Hengyang, 421001, China.
Tang YY; The Key Laboratory of Carcinogenesis of the Chinese Ministry of Health and The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute, Central South University, Changsha, Hunan, 410013, China.; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
Zhang P; School of Electronics and Information Engineering, Hunan University of Science and Engineering, Yongzhou, Hunan, 425100, China.; School of Information Science and Engineering, Central South University, Changsha, Hunan, 410000, China.
Wan W; Laboratory of Clinical Anatomy, University of South China, Hengyang, 421001, China.
Yao F; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
He PP; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
Xie W; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
Mo ZC; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
Shi JF; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
Wu JF; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
Peng J; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
Liu D; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
Cayabyab FS; Department of Surgery, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, S7N 5E5, Canada.
Zheng XL; Department of Biochemistry and Molecular Biology, The Libin Cardiovascular Institute of Alberta, The University of Calgary, Health Sciences Center, 3330 Hospital Dr NW, Calgary, Alberta, T2N 4N1, Canada.
Tang XY; Laboratory of Clinical Anatomy, University of South China, Hengyang, 421001, China.; Department of Radiology and Imaging Sciences, Emory University School of Medicine, WCI Suite C5018, 1701 Uppergate Drive, Atlanta, GA, 30322, United States of America.
Ouyang XP; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.
Tang CK; Institute of Cardiovascular Research, Key Laboratory for Atherosclerology of Hunan Province, Medical Research Center, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, Hunan, 421001, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Jun 13; Vol. 11 (6), pp. e0157265. Date of Electronic Publication: 2016 Jun 13 (Print Publication: 2016).
Typ publikacji:: Journal Article
MeSH Terms:: DNA Methylation*
Promoter Regions, Genetic*
ATP Binding Cassette Transporter 1/*genetics
Atherosclerosis/*genetics
Atherosclerosis/*pathology
Enhancer of Zeste Homolog 2 Protein/*metabolism
ATP Binding Cassette Transporter 1/metabolism ; Animals ; Apolipoproteins E/genetics ; Atherosclerosis/metabolism ; Cell Line ; Cholesterol/analysis ; Cholesterol/metabolism ; Down-Regulation ; Enhancer of Zeste Homolog 2 Protein/genetics ; Epigenesis, Genetic ; Gene Deletion ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; RAW 264.7 Cells