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Tytuł :
ER-to-Golgi protein delivery through an interwoven, tubular network extending from ER.
Autorzy :
Weigel AV; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Chang CL; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Shtengel G; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Xu CS; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Hoffman DP; 10X Genomics, Inc., Pleasanton, CA 94588, USA.
Freeman M; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA; Advanced Bioimaging Center, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Iyer N; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Aaron J; Advanced Imaging Center, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Khuon S; Advanced Imaging Center, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Bogovic J; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Qiu W; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Hess HF; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA.
Lippincott-Schwartz J; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 13. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Reducing acetylated tau is neuroprotective in brain injury.
Autorzy :
Shin MK; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Vázquez-Rosa E; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Koh Y; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Dhar M; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Chaubey K; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Cintrón-Pérez CJ; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Barker S; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Miller E; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Franke K; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Noterman MF; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Seth D; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Allen RS; Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, Atlanta, GA, USA; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, US.
Motz CT; Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, Atlanta, GA, USA; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, US.
Rao SR; Departments of Ophthalmology and Biochemistry, and the Neuroscience Graduate Program, SUNY-University at Buffalo, Buffalo, NY, USA; Research Service, VA Western NY Healthcare System, Buffalo, NY, USA.
Skelton LA; Departments of Ophthalmology and Biochemistry, and the Neuroscience Graduate Program, SUNY-University at Buffalo, Buffalo, NY, USA; Research Service, VA Western NY Healthcare System, Buffalo, NY, USA.
Pardue MT; Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Healthcare System, Atlanta, GA, USA; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, US.
Fliesler SJ; Departments of Ophthalmology and Biochemistry, and the Neuroscience Graduate Program, SUNY-University at Buffalo, Buffalo, NY, USA; Research Service, VA Western NY Healthcare System, Buffalo, NY, USA.
Wang C; Gladstone Institute of Neurological Disease, San Francisco, CA, USA.
Tracy TE; The Buck Institute, Novato, CA, USA.
Gan L; Helen and Robert Appel Alzheimer's Disease Research Institute, Weill Cornell Medicine, New York, NY, USA.
Liebl DJ; The Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Savarraj JPJ; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Torres GL; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Ahnstedt H; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
McCullough LD; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Kitagawa RS; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Choi HA; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Zhang P; Department of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH, USA.
Hou Y; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Chiang CW; Department of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH, USA.
Li L; Department of Biomedical Informatics, College of Medicine, Ohio State University, Columbus, OH, USA.
Ortiz F; Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX, USA.
Kilgore JA; Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX, USA.
Williams NS; Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX, USA.
Whitehair VC; MetroHealth Rehabilitation Institute, The MetroHealth System, Cleveland, OH; Department of Physical Medicine and Rehabilitation, Case Western Reserve University, School of Medicine, Cleveland, OH USA.
Gefen T; Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Flanagan ME; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Department of Pathology, Northwestern University, Chicago, IL, USA.
Stamler JS; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Jain MK; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Kraus A; Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, USA.
Cheng F; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Reynolds JD; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Departments of Anesthesiology & Perioperative Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Pieper AA; Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA; Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA; Geriatric Psychiatry, GRECC, Louis Stokes Cleveland VA Medical Center; Cleveland, OH, USA; Institute for Transformative Molecular Medicine, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Weill Cornell Autism Research Program, Weill Cornell Medicine of Cornell University, New York, NY, USA; Department of Neuroscience, Case Western Reserve University, School of Medicine, Cleveland, OH, USA. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 10. Date of Electronic Publication: 2021 Apr 10.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules.
Autorzy :
Tulpule A; Division of Pediatric Hematology/Oncology, UCSF, San Francisco, CA 94143, USA.
Guan J; Department of Pharmaceutical Chemistry, UCSF, San Francisco, CA 94143, USA; Department of Physics, University of Florida, Gainesville, FL 32611, USA.
Neel DS; Department of Medicine, Division of Hematology and Oncology, UCSF, San Francisco, CA 94143, USA.
Allegakoen HR; Division of Pediatric Hematology/Oncology, UCSF, San Francisco, CA 94143, USA.
Lin YP; Division of Pediatric Hematology/Oncology, UCSF, San Francisco, CA 94143, USA.
Brown D; Department of Pharmaceutical Chemistry, UCSF, San Francisco, CA 94143, USA.
Chou YT; Department of Medicine, Division of Hematology and Oncology, UCSF, San Francisco, CA 94143, USA.
Heslin A; Division of Pediatric Hematology/Oncology, UCSF, San Francisco, CA 94143, USA.
Chatterjee N; Department of Medicine, Division of Hematology and Oncology, UCSF, San Francisco, CA 94143, USA.
Perati S; Division of Pediatric Hematology/Oncology, UCSF, San Francisco, CA 94143, USA.
Menon S; Division of Pediatric Hematology/Oncology, UCSF, San Francisco, CA 94143, USA.
Nguyen TA; Department of Pathology and Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, CA 94143, USA.
Debnath J; Department of Pathology and Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, CA 94143, USA.
Ramirez AD; Department of Pharmaceutical Chemistry, UCSF, San Francisco, CA 94143, USA.
Shi X; Department of Pharmaceutical Chemistry, UCSF, San Francisco, CA 94143, USA.
Yang B; Department of Pharmaceutical Chemistry, UCSF, San Francisco, CA 94143, USA.
Feng S; UC Berkeley-UCSF Graduate Program in Bioengineering, UCSF, San Francisco, CA 94143, USA.
Makhija S; Department of Pathology and Helen Diller Family Comprehensive Cancer Center, UCSF, San Francisco, CA 94143, USA.
Huang B; Department of Pharmaceutical Chemistry, UCSF, San Francisco, CA 94143, USA; Department of Biochemistry and Biophysics, UCSF, San Francisco, CA 94143, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Electronic address: .
Bivona TG; Department of Medicine, Division of Hematology and Oncology, UCSF, San Francisco, CA 94143, USA. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 08. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
Autorzy :
Nuñez JK; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.
Chen J; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA.
Pommier GC; Department of Urology, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94158, USA.
Cogan JZ; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA; Tetrad Graduate Program, University of California, San Francisco, CA 94158, USA.
Replogle JM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; Tetrad Graduate Program, University of California, San Francisco, CA 94158, USA; Medical Scientist Training Program, University of California, San Francisco, CA 94158, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge 02142, USA.
Adriaens C; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02129, USA.
Ramadoss GN; Institute for Neurodegenerative Diseases, University of California, San Francisco, CA 94158.
Shi Q; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA.
Hung KL; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA.
Samelson AJ; Institute for Neurodegenerative Diseases, University of California, San Francisco, CA 94158.
Pogson AN; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge 02142, USA.
Kim JYS; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Chung A; Department of Urology, University of California, San Francisco, CA 94158, USA; Tetrad Graduate Program, University of California, San Francisco, CA 94158, USA.
Leonetti MD; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Chang HY; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Kampmann M; Institute for Neurodegenerative Diseases, University of California, San Francisco, CA 94158; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA.
Bernstein BE; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02129, USA.
Hovestadt V; Broad Institute of MIT and Harvard, Cambridge, MA 02139, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215, USA.
Gilbert LA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; Department of Urology, University of California, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94158, USA. Electronic address: .
Weissman JS; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, CA 94158, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge 02142, USA. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 07. Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Programmable protein circuit design.
Autorzy :
Chen Z; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Elowitz MB; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 05. Date of Electronic Publication: 2021 Apr 05.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
The long-term genetic stability and individual specificity of the human gut microbiome.
Autorzy :
Chen L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands.
Wang D; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands.
Garmaeva S; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands.
Kurilshikov A; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands.
Vich Vila A; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands; Department of Gastroenterology and Hepatology, Groningen 9713GZ, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands.
Gacesa R; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands; Department of Gastroenterology and Hepatology, Groningen 9713GZ, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands.
Sinha T; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands.
Segal E; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 7610001, Israel; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.
Weersma RK; Department of Gastroenterology and Hepatology, Groningen 9713GZ, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands.
Wijmenga C; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands.
Zhernakova A; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands. Electronic address: .
Fu J; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen 9713GZ, the Netherlands. Electronic address: .
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Corporate Authors :
Lifelines Cohort Study
Źródło :
Cell [Cell] 2021 Apr 04. Date of Electronic Publication: 2021 Apr 04.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes.
Autorzy :
Dentro SC; Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK; Big Data Institute, University of Oxford, Oxford OX3 7LF, UK.
Leshchiner I; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Haase K; Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Tarabichi M; Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.
Wintersinger J; University of Toronto, Toronto, ON M5S 3E1, Canada; Vector Institute, Toronto, ON M5G 1L7, Canada.
Deshwar AG; University of Toronto, Toronto, ON M5S 3E1, Canada; Vector Institute, Toronto, ON M5G 1L7, Canada.
Yu K; The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Rubanova Y; University of Toronto, Toronto, ON M5S 3E1, Canada; Vector Institute, Toronto, ON M5G 1L7, Canada.
Macintyre G; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK.
Demeulemeester J; Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Department of Human Genetics, University of Leuven, 3000 Leuven, Belgium.
Vázquez-García I; Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK; University of Cambridge, Cambridge CB2 0QQ, UK; Computational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Irving Institute for Cancer Dynamics, Columbia University, New York, NY 10027, USA.
Kleinheinz K; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Heidelberg University, 69120 Heidelberg, Germany.
Livitz DG; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Malikic S; Cancer Data Science Laboratory, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Donmez N; Simon Fraser University, Burnaby, BC V5A 1S6, Canada; Vancouver Prostate Centre, Vancouver, BC V6H 3Z6, Canada.
Sengupta S; NorthShore University HealthSystem, Evanston, IL 60201, USA.
Anur P; Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR 97231, USA.
Jolly C; Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Cmero M; University of Melbourne, Melbourne, VIC 3010, Australia; Walter + Eliza Hall Institute, Melbourne, VIC 3000, Australia.
Rosebrock D; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Schumacher SE; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Fan Y; The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Fittall M; Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Drews RM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK.
Yao X; Weill Cornell Medicine, New York, NY 10065, USA; New York Genome Center, New York, NY 10013, USA.
Watkins TBK; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London NW1 1AT, UK.
Lee J; University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Schlesner M; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Zhu H; The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Adams DJ; Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.
McGranahan N; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London WC1E 6BT, UK; Cancer Genome Evolution Research Group, University College London Cancer Institute, London WC1E 6DD, UK.
Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London WC1E 6BT, UK; Department of Medical Oncology, University College London Hospitals, London NW1 2BU, UK.
Getz G; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Massachusetts General Hospital Center for Cancer Research, Charlestown, MA 02129, USA; Massachusetts General Hospital, Department of Pathology, Boston, MA 02114, USA; Harvard Medical School, Boston, MA 02215, USA.
Boutros PC; University of Toronto, Toronto, ON M5S 3E1, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada; University of California, Los Angeles, Los Angeles, CA 90095, USA.
Imielinski M; Weill Cornell Medicine, New York, NY 10065, USA; New York Genome Center, New York, NY 10013, USA.
Beroukhim R; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Sahinalp SC; Cancer Data Science Laboratory, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Ji Y; NorthShore University HealthSystem, Evanston, IL 60201, USA; The University of Chicago, Chicago, IL 60637, USA.
Peifer M; Department of Translational Genomics, Center for Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931 Cologne, Germany.
Martincorena I; Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.
Markowetz F; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK.
Mustonen V; Organismal and Evolutionary Biology Research Programme, Department of Computer Science, Institute of Biotechnology, University of Helsinki, 00014 Helsinki, Finland.
Yuan K; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK; School of Computing Science, University of Glasgow, Glasgow G12 8RZ, UK.
Gerstung M; Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge CB10 1SD, UK; European Molecular Biology Laboratory, Genome Biology Unit, 69117 Heidelberg, Germany.
Spellman PT; Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR 97231, USA.
Wang W; The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Morris QD; University of Toronto, Toronto, ON M5S 3E1, Canada; Vector Institute, Toronto, ON M5G 1L7, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada; Computational and Systems Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Wedge DC; Big Data Institute, University of Oxford, Oxford OX3 7LF, UK; Oxford NIHR Biomedical Research Centre, Oxford OX4 2PG, UK; Manchester Cancer Research Centre, University of Manchester, Manchester M20 4GJ, UK.
Van Loo P; Cancer Genomics Laboratory, The Francis Crick Institute, London NW1 1AT, UK. Electronic address: .
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Corporate Authors :
PCAWG Evolution and Heterogeneity Working Group and the PCAWG Consortium
Źródło :
Cell [Cell] 2021 Apr 02. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Connecting communities to tackle cancer from many sides.
Źródło :
Cell [Cell] 2021 Apr 01. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Transforming lives through genetics.
Źródło :
Cell [Cell] 2021 Apr 01. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer.
Autorzy :
Levin M; Allen Discovery Center at Tufts University, Medford, MA, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 01. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
The next horizon in precision oncology: Proteogenomics to inform cancer diagnosis and treatment.
Autorzy :
Rodriguez H; Office of Cancer Clinical Proteomics Research, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: .
Zenklusen JC; Center for Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Staudt LM; Center for Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Doroshow JH; Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA; Office of the Director, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Lowy DR; Office of the Director, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
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Źródło :
Cell [Cell] 2021 Apr 01; Vol. 184 (7), pp. 1661-1670.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Unreliability of genotyping arrays for detecting very rare variants in human genetic studies: Example from a recent study of MC4R.
Autorzy :
Weedon MN; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Research, Innovation, Learning and Development building, Royal Devon & Exeter Hospital, Barrack Road, Exeter EX2 5DW, UK. Electronic address: .
Wright CF; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Research, Innovation, Learning and Development building, Royal Devon & Exeter Hospital, Barrack Road, Exeter EX2 5DW, UK.
Patel KA; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Research, Innovation, Learning and Development building, Royal Devon & Exeter Hospital, Barrack Road, Exeter EX2 5DW, UK.
Frayling TM; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Research, Innovation, Learning and Development building, Royal Devon & Exeter Hospital, Barrack Road, Exeter EX2 5DW, UK. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 01; Vol. 184 (7), pp. 1651.
Typ publikacji :
Letter
Opinia redakcyjna
Tytuł :
Whiteflies weaponize a plant defense via horizontal gene transfer.
Autorzy :
Whiteman NK; Department of Integrative Biology and Graduate Group in Microbiology, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: .
Tarnopol RL; Department of Integrative Biology and Graduate Group in Microbiology, University of California, Berkeley, Berkeley, CA 94720, USA.
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Źródło :
Cell [Cell] 2021 Apr 01; Vol. 184 (7), pp. 1657-1658.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Decaf or regular? Energizing the caffeine receptor.
Autorzy :
Stahl EL; The Scripps Research Institute, Department of Molecular Medicine, Jupiter, FL 33458, USA. Electronic address: .
Bohn LM; The Scripps Research Institute, Department of Molecular Medicine, Jupiter, FL 33458, USA. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 01; Vol. 184 (7), pp. 1659-1660.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A uniform format for manuscript submission.
Autorzy :
Zon LI; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA, USA. Electronic address: .
Boisvert JD; Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA; Stem Cell and Regenerative Biology Department, Harvard University, Cambridge, MA, USA.
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Corporate Authors :
Zon Lab
Źródło :
Cell [Cell] 2021 Apr 01; Vol. 184 (7), pp. 1654-1656.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Reply to Unreliability of genotyping arrays for detecting very rare variants in human genetic studies: Example from a recent study of MC4R.
Autorzy :
Lotta L; University of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Langenberg C; University of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
Wareham NJ; University of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK. Electronic address: .
Farooqi IS; University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 01; Vol. 184 (7), pp. 1652-1653.
Typ publikacji :
Letter
Opinia redakcyjna
Tytuł :
Whitefly hijacks a plant detoxification gene that neutralizes plant toxins.
Autorzy :
Xia J; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Guo Z; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Yang Z; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Han H; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Wang S; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Xu H; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Yang X; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Yang F; Key Laboratory of Molecular Biology of Heilongjiang Province, College of Life Sciences, Heilongjiang University, Harbin 150080, China.
Wu Q; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Xie W; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Zhou X; Department of Entomology, University of Kentucky, Lexington, KY 40546-0091, USA.
Dermauw W; Flanders Research Institute for Agriculture, Fisheries and Food (ILVO), Plant Sciences Unit, 8920 Merelbeke, Belgium; Department of Plants and Crops, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Ghent, Belgium.
Turlings TCJ; Laboratory of Fundamental and Applied Research in Chemical Ecology, Institute of Biology, University of Neuchâtel, 2000 Neuchâtel, Switzerland. Electronic address: .
Zhang Y; Department of Plant Protection, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 01; Vol. 184 (7), pp. 1693-1705.e17. Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelialization.
Autorzy :
Cronan MR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: .
Hughes EJ; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA; University Program in Genetics and Genomics, Duke University School of Medicine, Durham, NC 27710, USA.
Brewer WJ; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.
Viswanathan G; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.
Hunt EG; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.
Singh B; Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Mehra S; Tulane National Primate Research Center, Covington, LA 70433, USA.
Oehlers SH; Tuberculosis Research Program at the Centenary Institute, The University of Sydney, Camperdown, NSW, Australia; The University of Sydney, Faculty of Medicine and Health & Marie Bashir Institute, Camperdown, NSW, Australia.
Gregory SG; Duke Molecular Physiology Institute, Duke University, Durham, NC 27710, USA.
Kaushal D; Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Tobin DM; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Immunology, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: .
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Źródło :
Cell [Cell] 2021 Apr 01; Vol. 184 (7), pp. 1757-1774.e14. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article
Czasopismo naukowe

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