Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Cell Compartmentation"" wg kryterium: Temat


Tytuł :
A proximity-dependent biotinylation map of a human cell.
Autorzy :
Go CD; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Knight JDR; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.
Rajasekharan A; Montreal Neurological Institute and Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
Rathod B; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.
Hesketh GG; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.
Abe KT; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Youn JY; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada.
Samavarchi-Tehrani P; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.
Zhang H; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Zhu LY; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Popiel E; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Lambert JP; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.; Department of Molecular Medicine, Cancer Research Centre, Big Data Research Centre, Université Laval, Quebec City, Quebec, Canada.; CHU de Québec-Université Laval Research Center (CHUL), Quebec City, Quebec, Canada.
Coyaud É; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; PRISM INSERM U1192, Université de Lille, Villeneuve d'Ascq, France.
Cheung SWT; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.
Rajendran D; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.
Wong CJ; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.
Antonicka H; Montreal Neurological Institute and Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
Pelletier L; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Palazzo AF; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
Shoubridge EA; Montreal Neurological Institute and Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
Raught B; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Gingras AC; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Sinai Health System, Toronto, Ontario, Canada. .; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. .
Pokaż więcej
Źródło :
Nature [Nature] 2021 Jul; Vol. 595 (7865), pp. 120-124. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biotinylation*
Cell Compartmentation*
Protein Transport*
Proteome/*analysis
Proteome/*chemistry
Cells, Cultured ; Datasets as Topic ; Endoplasmic Reticulum/chemistry ; Endoplasmic Reticulum/metabolism ; HEK293 Cells ; HeLa Cells ; Homeostasis ; Humans ; Mass Spectrometry ; Mitochondria/chemistry ; Mitochondria/metabolism ; Organelles/chemistry ; Organelles/metabolism ; Proteome/metabolism ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
IDPology of the living cell: intrinsic disorder in the subcellular compartments of the human cell.
Autorzy :
Zhao B; Department of Computer Science, Virginia Commonwealth University, 401 West Main Street, Room E4225, Richmond, VA, 23284, USA.
Katuwawala A; Department of Computer Science, Virginia Commonwealth University, 401 West Main Street, Room E4225, Richmond, VA, 23284, USA.
Uversky VN; Department of Molecular Medicine, USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd. MDC07, Tampa, FL, 33612, USA. .; Laboratory of New Methods in Biology, Institute for Biological Instrumentation of the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, Russia. .
Kurgan L; Department of Computer Science, Virginia Commonwealth University, 401 West Main Street, Room E4225, Richmond, VA, 23284, USA. .
Pokaż więcej
Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Mar; Vol. 78 (5), pp. 2371-2385. Date of Electronic Publication: 2020 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Compartmentation*
Eukaryotic Cells/*metabolism
Intracellular Space/*metabolism
Intrinsically Disordered Proteins/*metabolism
Proteome/*metabolism
Cell Nucleus/metabolism ; Cytoskeleton/metabolism ; Databases, Protein/statistics & numerical data ; Humans ; Intrinsically Disordered Proteins/classification ; Models, Biological ; Proteome/classification
Czasopismo naukowe
Tytuł :
Wetting regulates autophagy of phase-separated compartments and the cytosol.
Autorzy :
Agudo-Canalejo J; Rudolf Peierls Centre for Theoretical Physics, University of Oxford, Oxford, UK.; Department of Chemistry, The Pennsylvania State University, University Park, PA, USA.; Department of Living Matter Physics, Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany.
Schultz SW; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Chino H; Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Migliano SM; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Saito C; Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Koyama-Honda I; Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Stenmark H; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Brech A; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Centre for Cancer Cell Reprogramming, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
May AI; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.; Tokyo Tech World Research Hub Initiative (WRHI), Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, Japan.
Mizushima N; Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Knorr RL; Graduate School and Faculty of Medicine, The University of Tokyo, Tokyo, Japan. .; Department of Theory and Bio-Systems, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany. .; Department of Molecular Physiology, Max Planck Institute of Molecular Plant Physiology, Potsdam, Germany. .
Pokaż więcej
Źródło :
Nature [Nature] 2021 Mar; Vol. 591 (7848), pp. 142-146. Date of Electronic Publication: 2021 Jan 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Autophagy*
Cell Compartmentation*
Wettability*
Autophagosomes/*metabolism
Cytosol/*metabolism
Adhesiveness ; Autophagosomes/chemistry ; Cell Line ; Cytosol/chemistry ; Humans ; Intracellular Membranes/chemistry ; Intracellular Membranes/metabolism ; Sequestosome-1 Protein/metabolism ; Surface Tension
Czasopismo naukowe
Tytuł :
High-resolution imaging reveals compartmentalization of mitochondrial protein synthesis in cultured human cells.
Autorzy :
Zorkau M; Faculty of Medical Sciences, Newcastle University Biosciences Institute, Newcastle upon Tyne NE2 4HH, United Kingdom.
Albus CA; Faculty of Medical Sciences, Newcastle University Biosciences Institute, Newcastle upon Tyne NE2 4HH, United Kingdom.
Berlinguer-Palmini R; Bioimaging Unit, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom.
Chrzanowska-Lightowlers ZMA; Faculty of Medical Sciences, Newcastle University Biosciences Institute, Newcastle upon Tyne NE2 4HH, United Kingdom; .
Lightowlers RN; Faculty of Medical Sciences, Newcastle University Biosciences Institute, Newcastle upon Tyne NE2 4HH, United Kingdom; .
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Feb 09; Vol. 118 (6).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Compartmentation*
Imaging, Three-Dimensional*
Protein Biosynthesis*
Mitochondrial Proteins/*biosynthesis
Alkynes ; Cells, Cultured ; DNA, Mitochondrial/genetics ; Glycine/analogs & derivatives ; Humans ; Kinetics ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Mitochondrial Ribosomes/metabolism ; RNA, Mitochondrial/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Euryarchaeal genomes are folded into SMC-dependent loops and domains, but lack transcription-mediated compartmentalization.
Autorzy :
Cockram C; Institut Pasteur, Unité Régulation Spatiale des Génomes, CNRS UMR 3525, 75015 Paris, France.
Thierry A; Institut Pasteur, Unité Régulation Spatiale des Génomes, CNRS UMR 3525, 75015 Paris, France.
Gorlas A; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.
Lestini R; Laboratoire d'Optique et Biosciences, École Polytechnique, CNRS UMR7645 - INSERM U1182, IP Paris, 91128 Palaiseau Cedex, France.
Koszul R; Institut Pasteur, Unité Régulation Spatiale des Génomes, CNRS UMR 3525, 75015 Paris, France. Electronic address: .
Pokaż więcej
Źródło :
Molecular cell [Mol Cell] 2021 Feb 04; Vol. 81 (3), pp. 459-472.e10. Date of Electronic Publication: 2020 Dec 30.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Compartmentation*
Chromosomes, Archaeal*
Genome, Archaeal*
Transcription, Genetic*
Chromatin/*genetics
DNA, Archaeal/*genetics
Euryarchaeota/*genetics
Chromatin Assembly and Disassembly ; Gene Expression Regulation, Archaeal ; Halobacterium salinarum/genetics ; Haloferax volcanii/genetics ; Nucleotide Motifs ; Phylogeny ; Thermococcus/genetics
Czasopismo naukowe
Tytuł :
RNA nucleation by MSL2 induces selective X chromosome compartmentalization.
Autorzy :
Valsecchi CIK; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Basilicata MF; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Georgiev P; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Gaub A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Seyfferth J; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Kulkarni T; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.; Faculty of Biology, University of Freiburg, Freiburg im Breisgau, Germany.
Panhale A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Semplicio G; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Manjunath V; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Holz H; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Dasmeh P; Institute for Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, Switzerland.
Akhtar A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg im Breisgau, Germany. .
Pokaż więcej
Źródło :
Nature [Nature] 2021 Jan; Vol. 589 (7840), pp. 137-142. Date of Electronic Publication: 2020 Nov 18.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Compartmentation*/genetics
DNA-Binding Proteins/*metabolism
Drosophila/*cytology
Drosophila/*genetics
Drosophila Proteins/*metabolism
RNA/*metabolism
Transcription Factors/*metabolism
X Chromosome/*genetics
X Chromosome/*metabolism
Animals ; Cell Line ; DNA-Binding Proteins/chemistry ; Drosophila/metabolism ; Drosophila Proteins/chemistry ; Female ; Humans ; Male ; Mice ; Nucleic Acid Conformation ; RNA/genetics ; Transcription Factors/chemistry
Czasopismo naukowe
Tytuł :
SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts.
Autorzy :
Gabanella F; CNR-Institute of Biochemistry and Cell Biology, Department of Sense Organs, Sapienza University of Rome, Viale del Policlinico, 155-00161, Rome, Italy. .; CNR-Institute of Molecular Biology and Pathology, Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291-00161, Rome, Italy. .
Onori A; CNR-Institute of Molecular Biology and Pathology, Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291-00161, Rome, Italy.
Ralli M; Department of Sense Organs, Sapienza University of Rome, Viale del Policlinico, 155-00161, Rome, Italy.
Greco A; Department of Sense Organs, Sapienza University of Rome, Viale del Policlinico, 155-00161, Rome, Italy.
Passananti C; CNR-Institute of Molecular Biology and Pathology, Department of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena, 291-00161, Rome, Italy.
Di Certo MG; CNR-Institute of Biochemistry and Cell Biology, Department of Sense Organs, Sapienza University of Rome, Viale del Policlinico, 155-00161, Rome, Italy. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2020 Nov 04; Vol. 10 (1), pp. 19000. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Compartmentation*
RNA, Messenger/*metabolism
Ribosomal Protein S6/*genetics
Survival of Motor Neuron 1 Protein/*physiology
Cell Membrane/metabolism ; Fibroblasts/metabolism ; Humans ; Protein Biosynthesis ; Protein Transport ; Ribosomes/metabolism
Czasopismo naukowe
Tytuł :
Location, Location, Location: Compartmentalization of NAD Synthesis and Functions in Mammalian Cells.
Autorzy :
Cambronne XA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: .
Kraus WL; Laboratory of Signaling and Gene Regulation, Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: .
Pokaż więcej
Źródło :
Trends in biochemical sciences [Trends Biochem Sci] 2020 Oct; Vol. 45 (10), pp. 858-873. Date of Electronic Publication: 2020 Jun 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Compartmentation*
NAD/*metabolism
Subcellular Fractions/*metabolism
Animals ; NAD/biosynthesis ; Signal Transduction
Czasopismo naukowe
Tytuł :
Prokaryotic Organelles: Bacterial Microcompartments in E. coli and Salmonella .
Autorzy :
Stewart KL; The Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA 50011.
Stewart AM; The Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA 50011.
Bobik TA; The Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA 50011.
Pokaż więcej
Źródło :
EcoSal Plus [EcoSal Plus] 2020 Oct; Vol. 9 (1).
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cell Compartmentation*
Bacterial Proteins/*metabolism
Escherichia coli/*metabolism
Prokaryotic Cells/*cytology
Salmonella/*metabolism
Bacterial Proteins/genetics ; Escherichia coli/cytology ; Escherichia coli/genetics ; Organelles ; Salmonella/cytology ; Salmonella/genetics
Czasopismo naukowe
Tytuł :
Compartmentalization-aided interaction screening reveals extensive high-order complexes within the SARS-CoV-2 proteome.
Autorzy :
Xu W; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, Beijing, China; Tsinghua-Peking Center for Life Sciences, Beijing, China; School of Life Sciences, Tsinghua University, Beijing, China.
Pei G; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, Beijing, China; Tsinghua-Peking Center for Life Sciences, Beijing, China; School of Life Sciences, Tsinghua University, Beijing, China.
Liu H; School of Life Sciences, Tsinghua University, Beijing, China.
Ju X; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, Beijing, China; School of Medicine, Tsinghua University, Beijing, China.
Wang J; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, Beijing, China; Tsinghua-Peking Center for Life Sciences, Beijing, China; School of Life Sciences, Tsinghua University, Beijing, China.
Ding Q; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, Beijing, China; School of Medicine, Tsinghua University, Beijing, China.
Li P; Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, Beijing, China; Tsinghua-Peking Center for Life Sciences, Beijing, China; School of Life Sciences, Tsinghua University, Beijing, China. Electronic address: .
Pokaż więcej
Źródło :
Cell reports [Cell Rep] 2021 Aug 03; Vol. 36 (5), pp. 109482. Date of Electronic Publication: 2021 Jul 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Proteome*
COVID-19/*virology
Protein Interaction Mapping/*methods
SARS-CoV-2/*pathogenicity
Viral Nonstructural Proteins/*physiology
Animals ; Caco-2 Cells ; Cell Compartmentation ; Cell Line ; Chlorocebus aethiops ; HEK293 Cells ; Humans ; Protein Interaction Maps ; Vero Cells ; Virus Replication
Czasopismo naukowe
Tytuł :
Norepinephrine Protects against Methamphetamine Toxicity through β2-Adrenergic Receptors Promoting LC3 Compartmentalization.
Autorzy :
Lazzeri G; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma 55, 56126 Pisa, Italy.
Busceti CL; I.R.C.C.S. Neuromed, Via Atinense 18, 86077 Pozzilli, Italy.
Biagioni F; I.R.C.C.S. Neuromed, Via Atinense 18, 86077 Pozzilli, Italy.
Fabrizi C; Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Via A. Borelli 50, 00161 Rome, Italy.
Morucci G; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma 55, 56126 Pisa, Italy.
Giorgi FS; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma 55, 56126 Pisa, Italy.
Ferrucci M; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma 55, 56126 Pisa, Italy.
Lenzi P; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma 55, 56126 Pisa, Italy.
Puglisi-Allegra S; I.R.C.C.S. Neuromed, Via Atinense 18, 86077 Pozzilli, Italy.
Fornai F; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Via Roma 55, 56126 Pisa, Italy.; I.R.C.C.S. Neuromed, Via Atinense 18, 86077 Pozzilli, Italy.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 05; Vol. 22 (13). Date of Electronic Publication: 2021 Jul 05.
Typ publikacji :
Journal Article
MeSH Terms :
Methamphetamine/*antagonists & inhibitors
Methamphetamine/*toxicity
Microtubule-Associated Proteins/*metabolism
Neurons/*drug effects
Neurons/*metabolism
Norepinephrine/*pharmacology
Receptors, Adrenergic, beta-2/*metabolism
Adrenergic Agents/pharmacology ; Animals ; Autophagy/drug effects ; Cell Compartmentation/drug effects ; Central Nervous System Stimulants/administration & dosage ; Central Nervous System Stimulants/antagonists & inhibitors ; Central Nervous System Stimulants/toxicity ; Desipramine/pharmacology ; Dose-Response Relationship, Drug ; Methamphetamine/administration & dosage ; Microscopy, Electron, Transmission ; Models, Neurological ; Neurons/ultrastructure ; Neuroprotective Agents/pharmacology ; Norepinephrine/metabolism ; PC12 Cells ; Rats ; Vacuoles/drug effects ; Vacuoles/metabolism ; Vacuoles/ultrastructure
Czasopismo naukowe
Tytuł :
Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling.
Autorzy :
Zhang JZ; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Lu TW; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Stolerman LM; Department of Mechanical and Aerospace Engineering, University of California, San Diego, La Jolla, CA 92093, USA.
Tenner B; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.
Yang JR; Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Zhang JF; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA.
Falcke M; Mathematical Cell Physiology, Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany; Department of Physics, Humboldt University, 12489 Berlin, Germany.
Rangamani P; Department of Mechanical and Aerospace Engineering, University of California, San Diego, La Jolla, CA 92093, USA.
Taylor SS; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Mehta S; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.
Zhang J; Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA; Department of Pharmacology and Molecular Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: .
Pokaż więcej
Źródło :
Cell [Cell] 2020 Sep 17; Vol. 182 (6), pp. 1531-1544.e15. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Signal Transduction*
Carcinogenesis/*metabolism
Carcinoma, Hepatocellular/*genetics
Cell Compartmentation/*genetics
Cyclic AMP/*metabolism
Cyclic AMP-Dependent Protein Kinase RIalpha Subunit/*metabolism
HSP40 Heat-Shock Proteins/*genetics
Liver Neoplasms/*genetics
Animals ; Carcinogenesis/drug effects ; Carcinogenesis/genetics ; Carcinoma, Hepatocellular/metabolism ; Cell Compartmentation/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Cyclic AMP/pharmacology ; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit/genetics ; Cyclic AMP-Dependent Protein Kinases/genetics ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Cytoplasm/metabolism ; Humans ; Liver Neoplasms/metabolism ; Mice ; Oncogenes/genetics ; Protein Domains ; Rats ; Rats, Sprague-Dawley ; Recombinant Fusion Proteins ; Spectroscopy, Fourier Transform Infrared ; Time-Lapse Imaging/methods
SCR Disease Name :
Fibrolamellar hepatocellular carcinoma
Czasopismo naukowe
Tytuł :
The RNase J-Based RNA Degradosome Is Compartmentalized in the Gastric Pathogen Helicobacter pylori.
Autorzy :
Tejada-Arranz A; Institut Pasteur, Département de Microbiologie, Unité Pathogenèse de Helicobacter, UMR CNRS 2001, Paris, France.; Université de Paris, Sorbonne Paris Cité, Cellule Pasteur, Paris, France.
Galtier E; Institut Pasteur, Département de Microbiologie, Unité Pathogenèse de Helicobacter, UMR CNRS 2001, Paris, France.; Université de Paris, Sorbonne Paris Cité, Cellule Pasteur, Paris, France.
El Mortaji L; Institut Pasteur, Département de Microbiologie, Unité Pathogenèse de Helicobacter, UMR CNRS 2001, Paris, France.
Turlin E; Institut Pasteur, Département de Microbiologie, Unité Pathogenèse de Helicobacter, UMR CNRS 2001, Paris, France.
Ershov D; Image Analysis Hub, C2RT, Institut Pasteur, Paris, France.; Bioinformatics and Biostatistics HUB, Department of Computational Biology, Institut Pasteur, USR 3756 CNRS, Paris, France.
De Reuse H; Institut Pasteur, Département de Microbiologie, Unité Pathogenèse de Helicobacter, UMR CNRS 2001, Paris, France .
Pokaż więcej
Źródło :
MBio [mBio] 2020 Sep 15; Vol. 11 (5). Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Bacterial*
Cell Compartmentation/*genetics
Endoribonucleases/*metabolism
Helicobacter pylori/*enzymology
Helicobacter pylori/*genetics
Multienzyme Complexes/*metabolism
Polyribonucleotide Nucleotidyltransferase/*metabolism
RNA Helicases/*metabolism
RNA, Bacterial/*metabolism
Ribonucleases/*genetics
Cell Compartmentation/physiology ; Helicobacter pylori/pathogenicity ; RNA Stability ; RNA, Bacterial/genetics ; RNA, Messenger ; Ribonucleases/metabolism
Czasopismo naukowe
Tytuł :
Compartment and cell-type specific hypoxia responses in the developing Drosophila brain.
Autorzy :
Baccino-Calace M; Developmental Neurobiology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo 11600, Uruguay.
Prieto D; Developmental Neurobiology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo 11600, Uruguay.
Cantera R; Developmental Neurobiology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo 11600, Uruguay.; Zoology Department, Stockholm University, Stockholm 106 91, Sweden.
Egger B; Department of Biology, University of Fribourg, Fribourg CH-1700, Switzerland .
Pokaż więcej
Źródło :
Biology open [Biol Open] 2020 Aug 18; Vol. 9 (8). Date of Electronic Publication: 2020 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Compartmentation*
Brain/*growth & development
Brain/*pathology
Drosophila melanogaster/*cytology
Drosophila melanogaster/*growth & development
Hypoxia/*pathology
Animals ; Biosensing Techniques ; Cell Differentiation ; Cell Hypoxia/drug effects ; Gene Expression Regulation/drug effects ; Glycolysis/drug effects ; Glycolysis/genetics ; Green Fluorescent Proteins/metabolism ; Hypoxia/genetics ; Larva/drug effects ; Neuroepithelial Cells/drug effects ; Neuroepithelial Cells/metabolism ; Optic Lobe, Nonmammalian/pathology ; Oxygen/pharmacology
Czasopismo naukowe
Tytuł :
Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein.
Autorzy :
Tascioglu Aliyev A; Division of Radiation Health, Pharmaceutical Sciences, University of Arkansas for Medical Sciences; Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Ege University.
LoBianco F; Division of Radiation Health, Pharmaceutical Sciences, University of Arkansas for Medical Sciences.
Krager KJ; Division of Radiation Health, Pharmaceutical Sciences, University of Arkansas for Medical Sciences.
Aykin-Burns N; Division of Radiation Health, Pharmaceutical Sciences, University of Arkansas for Medical Sciences; .
Pokaż więcej
Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 Jun 18 (160). Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Cell Compartmentation*
Green Fluorescent Proteins/*metabolism
Biosensing Techniques/methods ; Cell Line, Tumor ; Cysteine/metabolism ; Cystine/metabolism ; Cytosol/metabolism ; Data Analysis ; Humans ; Hydrogen Peroxide/metabolism ; Image Processing, Computer-Assisted ; Microscopy, Fluorescence ; Oxidation-Reduction ; Subcellular Fractions/metabolism ; Transduction, Genetic
Czasopismo naukowe
Tytuł :
The Role of Liquid-Liquid Phase Separation in the Compartmentalization of Cell Nucleus and Spatial Genome Organization.
Autorzy :
Razin SV; Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia. .; Lomonosov Moscow State University, Faculty of Biology, Moscow, 119991, Russia.
Gavrilov AA; Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.
Pokaż więcej
Źródło :
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2020 Jun; Vol. 85 (6), pp. 643-650.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cell Compartmentation*
Genome, Human*
Transcription, Genetic*
Cell Nucleus/*ultrastructure
Chromatin/*ultrastructure
Chromosomes, Human/*genetics
Liquid-Liquid Extraction/*methods
Cell Nucleus/genetics ; Cell Nucleus/metabolism ; Chromatin/metabolism ; Chromosome Positioning ; Humans ; Nuclear Proteins/genetics
Czasopismo naukowe
Tytuł :
Mechanisms and Functions of Chromosome Compartmentalization.
Autorzy :
Hildebrand EM; Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Dekker J; Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: .
Pokaż więcej
Źródło :
Trends in biochemical sciences [Trends Biochem Sci] 2020 May; Vol. 45 (5), pp. 385-396. Date of Electronic Publication: 2020 Feb 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Compartmentation*
Chromosomes*
Transcription, Genetic
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies