Temat: "Cell Cycle Checkpoints" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling.
Autorzy:: Zhang Y; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Young R; Chester Beatty Laboratories, Structural Biology Division, Institute of Cancer Research, London, UK.
Garvanska DH; The NNF Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.
Song C; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Zhai Y; School of Public Health, Qingdao University, Qingdao, China.
Wang Y; School of Public Health, Qingdao University, Qingdao, China.
Jiang H; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Fang J; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Nilsson J; The NNF Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.
Alfieri C; Chester Beatty Laboratories, Structural Biology Division, Institute of Cancer Research, London, UK. .
Zhang G; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China. zhanggang_.; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2024 Feb 09; Vol. 7 (1), pp. 164. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:: Journal Article
MeSH Terms:: Cdc20 Proteins*/chemistry
Cdc20 Proteins*/genetics
Cdc20 Proteins*/metabolism
M Phase Cell Cycle Checkpoints*/genetics
Spindle Apparatus*/genetics
Spindle Apparatus*/metabolism
Anaphase-Promoting Complex-Cyclosome/genetics ; Anaphase-Promoting Complex-Cyclosome/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Signal Transduction ; Humans

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Skocz do pozycji: 2.

Tytuł:: Paradol Induces Cell Cycle Arrest and Apoptosis in Glioblastoma Cells.
Autorzy:: Wang R; Department of Stem Cells and Regenerative Medicine, Key Laboratory of Cell Biology, National Health Commission of China, and Key Laboratory of Medical Cell Biology, Ministry of Education of China, China Medical University, Shenyang, China.
Liu T; Department of Pathology, Central Hospital of Yingkou Economic and Technological Development Zone, Yingkou, China.
Chen J; Department of Stem Cells and Regenerative Medicine, Key Laboratory of Cell Biology, National Health Commission of China, and Key Laboratory of Medical Cell Biology, Ministry of Education of China, China Medical University, Shenyang, China.
Zhang D; Department of Stem Cells and Regenerative Medicine, Key Laboratory of Cell Biology, National Health Commission of China, and Key Laboratory of Medical Cell Biology, Ministry of Education of China, China Medical University, Shenyang, China.; Pokaż więcej
Źródło:: Nutrition and cancer [Nutr Cancer] 2022; Vol. 74 (8), pp. 3007-3014. Date of Electronic Publication: 2022 Jan 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*
Cell Cycle Checkpoints*
Glioblastoma*/pathology
Guaiacol*/analogs & derivatives
Guaiacol*/pharmacology
Cell Cycle ; Cell Line, Tumor ; Cell Proliferation ; Cell Survival ; G1 Phase Cell Cycle Checkpoints ; Humans ; p38 Mitogen-Activated Protein Kinases/metabolism

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Skocz do pozycji: 3.

Tytuł:: Large-scale phosphoproteomics reveals activation of the MAPK/GADD45β/P38 axis and cell cycle inhibition in response to BMP9 and BMP10 stimulation in endothelial cells.
Autorzy:: Al Tarrass M; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France.
Belmudes L; Grenoble Alpes University, CEA, INSERM, UA13 BGE, CNRS, CEA, FR2048, Grenoble, France.
Koça D; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France.
Azemard V; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France.
Liu H; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France.
Al Tabosh T; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France.
Ciais D; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France.; Present address: Université Côte d'Azur, CNRS, INSERM, iBV, Nice, France.
Desroches-Castan A; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France.
Battail C; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France.; Grenoble Alpes University, CEA, INSERM, UA13 BGE, CNRS, CEA, FR2048, Grenoble, France.
Couté Y; Grenoble Alpes University, CEA, INSERM, UA13 BGE, CNRS, CEA, FR2048, Grenoble, France.
Bouvard C; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France.
Bailly S; Biosanté Unit U1292, Grenoble Alpes University, CEA, Grenoble, 38000, France. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Mar 04; Vol. 22 (1), pp. 158. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Endothelial Cells*
Bone Morphogenetic Proteins*
Cell Cycle Checkpoints ; Phosphorylation ; G1 Phase Cell Cycle Checkpoints

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Skocz do pozycji: 4.

Tytuł:: Biomedical association analysis between G2/M checkpoint genes and susceptibility to HIV-1 infection and AIDS progression from a northern chinese MSM population.
Autorzy:: Wu J; College of Basic Medicine, Harbin Medical University-Daqing Campus, Daqing, Heilongjiang Province, 163319, China.
Xu L; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China.
Liu B; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.
Sun W; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China.
Hu Y; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.
Yang Y; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.
Guo K; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.
Jia X; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China.
Sun H; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China.
Wu J; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China.
Huang Y; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China.
Ji W; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China.
Fu S; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China.; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China.
Qiao Y; College of Basic Medicine, Harbin Medical University-Daqing Campus, Daqing, Heilongjiang Province, 163319, China. .; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China. .; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China. .
Zhang X; Laboratory of Medical Genetics, Harbin Medical University, Harbin, Heilongjiang Province, 150081, China. .; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China, Harbin Medical University, Ministry of Education, Harbin, Heilongjiang Province, 150081, China. .; Pokaż więcej
Źródło:: AIDS research and therapy [AIDS Res Ther] 2023 Jul 19; Vol. 20 (1), pp. 51. Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acquired Immunodeficiency Syndrome*/epidemiology
Acquired Immunodeficiency Syndrome*/genetics
HIV Infections*/epidemiology
HIV Infections*/genetics
Sexual and Gender Minorities*
Cell Cycle Checkpoints*/genetics
Humans ; Male ; East Asian People ; HIV-1 ; Homosexuality, Male

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Skocz do pozycji: 5.

Tytuł:: CDC45 promotes the stemness and metastasis in lung adenocarcinoma by affecting the cell cycle.
Autorzy:: Liu Y; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China.; Anhui Province Engineering Laboratory of Occupational Health and Safety, Anhui University of Science and Technology, Huainan, People's Republic of China.
Han T; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China.; Anhui Province Engineering Laboratory of Occupational Health and Safety, Anhui University of Science and Technology, Huainan, People's Republic of China.
Xu Z; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China.
Wu J; Joint Research Center for Occupational Medicine and Health of IHM, School of Medicine, Anhui University of Science and Technology, Huainan, People's Republic of China. .
Zhou J; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China.; Anhui Province Engineering Laboratory of Occupational Health and Safety, Anhui University of Science and Technology, Huainan, People's Republic of China.
Guo J; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China.; Anhui Province Engineering Laboratory of Occupational Health and Safety, Anhui University of Science and Technology, Huainan, People's Republic of China.
Miao R; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China.
Xing Y; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China.; Department of Clinical Laboratory, Anhui Zhongke Gengjiu Hospital, Hefei, People's Republic of China.
Ge D; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China.; Anhui Province Engineering Laboratory of Occupational Health and Safety, Anhui University of Science and Technology, Huainan, People's Republic of China.
Bai Y; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China. by0319_.; Anhui Province Engineering Laboratory of Occupational Health and Safety, Anhui University of Science and Technology, Huainan, People's Republic of China. by0319_.
Hu D; School of Medicine, Anhui University of Science and Technology, Chongren Building, No 168, Taifeng St, Huainan, 232001, People's Republic of China. .; Anhui Province Engineering Laboratory of Occupational Health and Safety, Anhui University of Science and Technology, Huainan, People's Republic of China. .; Key Laboratory of Industrial Dust Prevention and Control & Occupational Safety and Health of the Ministry of Education, Anhui University of Science and Technology, Huainan, People's Republic of China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2024 Apr 08; Vol. 22 (1), pp. 335. Date of Electronic Publication: 2024 Apr 08.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/pathology
Adenocarcinoma of Lung*/genetics
Animals ; Mice ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Cycle Checkpoints/genetics ; Cell Division ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Cell Movement/genetics ; Gene Expression Regulation, Neoplastic

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Skocz do pozycji: 6.

Tytuł:: Spindle checkpoint activation by fungal orthologs of the S. cerevisiae Mps1 kinase.
Autorzy:: Fabritius A; Department of Molecular and Cellular Biology, University of California, Davis, CA, United States of America.
Alonso A; BOND PET FOODS, Boulder, CO, United States of America.
Wood A; Research and Development, Mawi DNA Technologies LLC, Pleasanton, CA, United States of America.
Sulthana S; Department of Molecular and Cellular Biology, University of California, Davis, CA, United States of America.
Winey M; Department of Molecular and Cellular Biology, University of California, Davis, CA, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 26; Vol. 19 (3), pp. e0301084. Date of Electronic Publication: 2024 Mar 26 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Humans ; Antifungal Agents/metabolism ; Cell Cycle Proteins/metabolism ; M Phase Cell Cycle Checkpoints ; Prospective Studies ; Protein Serine-Threonine Kinases/metabolism ; Protein-Tyrosine Kinases/metabolism ; Spindle Apparatus/metabolism

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Skocz do pozycji: 7.

Tytuł:: MAX controls meiotic entry in sexually undifferentiated germ cells.
Autorzy:: Suzuki A; Division of Biomedical Sciences, Research Center for Genomic Medicine, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1241, Japan.
Uranishi K; Division of Biomedical Sciences, Research Center for Genomic Medicine, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1241, Japan.
Nishimoto M; Division of Biomedical Sciences, Research Center for Genomic Medicine, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1241, Japan.
Mizuno Y; Division of Morphological Science, Biomedical Research Center, Saitama Medical University, 38 Morohongo, Moroyama, Iruma-gun, Saitama, 350-0495, Japan.
Mizuno S; Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Takahashi S; Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Eisenman RN; Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.
Okuda A; Division of Biomedical Sciences, Research Center for Genomic Medicine, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1241, Japan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 04; Vol. 14 (1), pp. 5236. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: Factor X*
Meiosis*/genetics
Animals ; Female ; Male ; Mice ; Apoptosis ; Cell Cycle Checkpoints ; Germ Cells

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Skocz do pozycji: 8.

Tytuł:: Different Impacts of DNA-PK and mTOR Kinase Inhibitors in Combination with Ionizing Radiation on HNSCC and Normal Tissue Cells.
Autorzy:: Klieber N; Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Hildebrand LS; Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Faulhaber E; Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Symank J; Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Häck N; Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Härtl A; Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Fietkau R; Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.
Distel LV; Department of Radiation Oncology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 27, 91054 Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), 91054 Erlangen, Germany.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Feb 06; Vol. 13 (4). Date of Electronic Publication: 2024 Feb 06.
Typ publikacji:: Journal Article
MeSH Terms:: Head and Neck Neoplasms*/drug therapy
Head and Neck Neoplasms*/radiotherapy
Papillomavirus Infections*
Squamous Cell Carcinoma of Head and Neck*/drug therapy
Squamous Cell Carcinoma of Head and Neck*/radiotherapy
Humans ; Apoptosis ; Cell Line, Tumor ; G2 Phase Cell Cycle Checkpoints ; Radiation, Ionizing ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; DNA-Activated Protein Kinase/antagonists & inhibitors

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Skocz do pozycji: 9.

Tytuł:: Involucrasin B Inhibits the Proliferation of Caco-2 Cells by Regulating the TGFβ/SMAD2-3-4 Pathway.
Autorzy:: Wang Z; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Lin W; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Shi M; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Hou Y; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Liu J; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Huang Z; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Zhang X; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Yang Y; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Liu B; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.
Yang Z; School of Traditional Chinese Medicine, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China.
Ma W; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 01; Vol. 29 (3). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:: Journal Article
MeSH Terms:: Transforming Growth Factor beta*/pharmacology
Humans ; Caco-2 Cells ; Phosphorylation ; G1 Phase Cell Cycle Checkpoints ; Cell Proliferation ; Cell Line, Tumor ; Smad2 Protein

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Skocz do pozycji: 10.

Tytuł:: Meiotic cells escape prolonged spindle checkpoint activity through kinetochore silencing and slippage.
Autorzy:: MacKenzie A; Department of Biology, Indiana University, Bloomington, Indiana, United States of America.
Vicory V; Department of Biology, Indiana University, Bloomington, Indiana, United States of America.
Lacefield S; Department of Biology, Indiana University, Bloomington, Indiana, United States of America.; Department of Biochemistry and Cell Biology, the Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America.; Pokaż więcej
Źródło:: PLoS genetics [PLoS Genet] 2023 Apr 05; Vol. 19 (4), pp. e1010707. Date of Electronic Publication: 2023 Apr 05 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Cell Cycle Checkpoints*
Kinetochores*/metabolism
Spindle Apparatus*/genetics
Spindle Apparatus*/metabolism
Meiosis*
Saccharomyces cerevisiae*/cytology
Saccharomyces cerevisiae*/genetics
Saccharomyces cerevisiae*/metabolism
Anaphase-Promoting Complex-Cyclosome/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Chromosome Segregation ; Germ Cells/metabolism ; Microtubules/genetics ; Microtubules/metabolism ; Mitosis

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Skocz do pozycji: 11.

Tytuł:: Anti-proliferative effect of melatonin in human hepatoma HepG2 cells occurs mainly through cell cycle arrest and inflammation inhibition.
Autorzy:: Nabih HK; Medical Biochemistry Department, Medicine and Clinical Studies Research Institute, National Research Centre, 33 El Bohouth St., Dokki, Giza, 12622, Egypt. .
Hamed AR; Chemistry of Medicinal Plants Department, and Biology Unit, Central Laboratory for Pharmaceutical and Drug Industries Research Institute, National Research Centre, 33 El Bohouth St., Dokki, Giza, 12622, Egypt.
Yahya SMM; Hormones Department, Medicine and Clinical Studies Research Institute, and Stem Cell Lab, Centre of Excellence for Advanced Sciences, National Research Centre, 33 El Bohouth St., Dokki, Giza, 12622, Egypt.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Mar 16; Vol. 13 (1), pp. 4396. Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/metabolism
Cell Cycle Checkpoints*/drug effects
Inflammation*/drug therapy
Liver Neoplasms*/drug therapy
Liver Neoplasms*/metabolism
Melatonin*/pharmacology
Melatonin*/therapeutic use
Humans ; Apoptosis ; Cell Cycle ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Hep G2 Cells

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Skocz do pozycji: 12.

Tytuł:: RTA dh404 Induces Cell Cycle Arrest, Apoptosis, and Autophagy in Glioblastoma Cells.
Autorzy:: Tsai TH; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807378, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.; Graduate Institutes of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.; Division of Neurosurgery, Department of Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung 80145, Taiwan.
Su YF; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807378, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.; Graduate Institutes of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Tsai CY; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807378, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.; Graduate Institutes of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Wu CH; Division of Neurosurgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung 807378, Taiwan.; Department of Surgery, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.; Graduate Institutes of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Lee KT; Division of Neurosurgery, Department of Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung 80145, Taiwan.
Hsu YC; School of Medicine, I-Shou University, Kaohsiung 82445, Taiwan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 16; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Apoptosis*/drug effects
Autophagy*/drug effects
Cell Cycle Checkpoints*/drug effects
Glioblastoma*/pathology
Oleanolic Acid*/pharmacology
Humans ; Cell Line, Tumor ; Cell Proliferation/drug effects

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Skocz do pozycji: 13.

Tytuł:: Novel chemotherapeutic agent FX-9 activates NF-κB signaling and induces G1 phase arrest by activating CDKN1A in a human prostate cancer cell line.
Autorzy:: Weiner F; Small Animal Clinic, University of Veterinary Medicine Hannover, 30559, Hannover, Germany.; Department of Medicine, Clinic III, Hematology, Oncology, Palliative Medicine, University of Rostock, 18057, Rostock, Germany.
Schille JT; Small Animal Clinic, University of Veterinary Medicine Hannover, 30559, Hannover, Germany.; Department of Medicine, Clinic III, Hematology, Oncology, Palliative Medicine, University of Rostock, 18057, Rostock, Germany.
Koczan D; Core Facility for Microarray Analysis, Institute for Immunology, University of Rostock, 18057, Rostock, Germany.
Wu XF; Leibniz Institute for Catalysis, 18059, Rostock, Germany.
Beller M; Leibniz Institute for Catalysis, 18059, Rostock, Germany.
Junghanss C; Department of Medicine, Clinic III, Hematology, Oncology, Palliative Medicine, University of Rostock, 18057, Rostock, Germany.
Hewicker-Trautwein M; Department of Pathology, University of Veterinary Medicine Hannover, 30559, Hannover, Germany.
Murua Escobar H; Department of Medicine, Clinic III, Hematology, Oncology, Palliative Medicine, University of Rostock, 18057, Rostock, Germany.; Comprehensive Cancer Center - Mecklenburg Vorpommern (CCC-MV), Campus Rostock, University of Rostock, 18057, Rostock, Germany.
Nolte I; Small Animal Clinic, University of Veterinary Medicine Hannover, 30559, Hannover, Germany. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2021 Oct 08; Vol. 21 (1), pp. 1088. Date of Electronic Publication: 2021 Oct 08.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*pharmacology
Cyclin-Dependent Kinase Inhibitor p21/*metabolism
G1 Phase Cell Cycle Checkpoints/*drug effects
Isoquinolines/*pharmacology
NF-kappa B/*metabolism
Prostatic Neoplasms, Castration-Resistant/*metabolism
Antineoplastic Agents/therapeutic use ; E2F1 Transcription Factor/antagonists & inhibitors ; G1 Phase Cell Cycle Checkpoints/genetics ; Gene Expression/drug effects ; Gene Expression Profiling/methods ; Humans ; Isoquinolines/therapeutic use ; Male ; Middle Aged ; PC-3 Cells ; Plasminogen Activator Inhibitor 1/metabolism ; Prostatic Neoplasms, Castration-Resistant/genetics ; S Phase Cell Cycle Checkpoints ; Time Factors ; Tissue Array Analysis

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Skocz do pozycji: 14.

Tytuł:: Key Proteins of Replication Stress Response and Cell Cycle Control as Cancer Therapy Targets.
Autorzy:: Khamidullina AI; Laboratory of Molecular Oncobiology, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.
Abramenko YE; Laboratory of Molecular Oncobiology, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.
Bruter AV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.
Tatarskiy VV; Laboratory of Molecular Oncobiology, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov Street, 119334 Moscow, Russia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 19; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 19.
Typ publikacji:: Journal Article; Review
MeSH Terms:: DNA Damage*
Neoplasms*/drug therapy
Neoplasms*/genetics
Ataxia Telangiectasia Mutated Proteins/metabolism ; Checkpoint Kinase 1/genetics ; Checkpoint Kinase 1/metabolism ; Cell Cycle Checkpoints ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; DNA Replication

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Skocz do pozycji: 15.

Tytuł:: Clerodendrum chinense Stem Extract and Nanoparticles: Effects on Proliferation, Colony Formation, Apoptosis Induction, Cell Cycle Arrest, and Mitochondrial Membrane Potential in Human Breast Adenocarcinoma Breast Cancer Cells.
Autorzy:: Chittasupho C; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.; Center of Excellence in Pharmaceutical Nanotechnology, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Samee W; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Srinakharinwirot University, Nakhonnayok 26120, Thailand.
Na Takuathung M; Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.; Clinical Research Center for Food and Herbal Product Trials and Development (CR-FAH), Chiang Mai 50200, Thailand.
Okonogi S; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.; Center of Excellence in Pharmaceutical Nanotechnology, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Nimkulrat S; Faculty of Pharmacy, Siam University, Bangkok 10160, Thailand.
Athikomkulchai S; Department of Pharmacognosy, Faculty of Pharmacy, Srinakharinwirot University, Nakhonnayok 26120, Thailand.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 12; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:: Journal Article
MeSH Terms:: Clerodendrum*
Breast Neoplasms*/drug therapy
Adenocarcinoma*
Humans ; Female ; Membrane Potential, Mitochondrial ; Apoptosis ; Cell Cycle Checkpoints ; HeLa Cells ; Cell Proliferation ; Plant Extracts/pharmacology

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Skocz do pozycji: 16.

Tytuł:: Marinopyrrole derivative MP1 as a novel anti-cancer agent in group 3 MYC-amplified Medulloblastoma.
Autorzy:: Coulter DW; Department of Pediatrics, Hematology/Oncology Division, University of Nebraska Medical Center, Omaha, NE, 68198, USA.; Child Health Research Institute, University of Nebraska Medical Center, Omaha, NE, 68198, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Chhonker YS; Department of Pharmacy Practice & Science, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Kumar D; Department of Pediatrics, Hematology/Oncology Division, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Kesherwani V; Child Health Research Institute, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Aldhafiri WN; Department of Pharmacy Practice & Science, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
McIntyre EM; Department of Pediatrics, Hematology/Oncology Division, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Alexander G; Department of Pediatrics, Hematology/Oncology Division, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Ray S; Department of Pediatrics, Hematology/Oncology Division, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Joshi SS; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Li R; Department of Pharmacy Practice & Science, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Murry DJ; Department of Pharmacy Practice & Science, University of Nebraska Medical Center, Omaha, NE, 68198, USA.; Child Health Research Institute, University of Nebraska Medical Center, Omaha, NE, 68198, USA.; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Chaturvedi NK; Department of Pediatrics, Hematology/Oncology Division, University of Nebraska Medical Center, Omaha, NE, 68198, USA. .; Child Health Research Institute, University of Nebraska Medical Center, Omaha, NE, 68198, USA. .; Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA. .; Department of Pediatrics, Hematology and Oncology Division, University of Nebraska Medical Center, Omaha, NE, 68198, USA. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Jan 11; Vol. 43 (1), pp. 18. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:: Journal Article
MeSH Terms:: Medulloblastoma*/drug therapy
Medulloblastoma*/genetics
Cerebellar Neoplasms*/drug therapy
Cerebellar Neoplasms*/genetics
Sirolimus/*analogs & derivatives
Humans ; Animals ; Mice ; G2 Phase Cell Cycle Checkpoints ; TOR Serine-Threonine Kinases

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Skocz do pozycji: 17.

Tytuł:: Anti-cancer effects of DHP107 on canine mammary gland cancer examined through in-vitro and in-vivo mouse xenograft models.
Autorzy:: Chae HK; Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.; Department of Veterinary Internal Medicine, Western Referral Animal Medical Center, Seoul, Republic of Korea.
Oh YI; Department of Veterinary Internal Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea.
Lim GH; Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Jung YC; Laboratory Animal Center, CHA University, CHA Biocomplex, Sungnam, Republic of Korea.
Park SH; Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
An JH; Department of Veterinary Emergency and Critical Care Medicine and Institute of Veterinary Science, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Park SM; Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Seo KW; Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
Chu SN; Pangyo Research Laboratory, DaeHwa Pharmaceutical Co. Ltd, Sungnam, Republic of Korea.
Li Q; Department of Veterinary Medicine, College of Agriculture, YanBian University, YanJi, JiLin, 133000, China. .
Youn HY; Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea. .; Pokaż więcej
Źródło:: BMC veterinary research [BMC Vet Res] 2024 Jan 03; Vol. 20 (1), pp. 3. Date of Electronic Publication: 2024 Jan 03.
Typ publikacji:: Journal Article
MeSH Terms:: Dog Diseases*/drug therapy
Breast Neoplasms*/veterinary
Animals ; Dogs ; Mice ; Apoptosis ; Cell Cycle Checkpoints ; Cell Line, Tumor ; Cell Proliferation ; Paclitaxel/pharmacology ; Paclitaxel/therapeutic use

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Skocz do pozycji: 18.

Tytuł:: Acetylcorynoline Induces Apoptosis and G2/M Phase Arrest through the c-Myc Signaling Pathway in Colon Cancer Cells.
Autorzy:: Park YR; College of Korean Medicine, Kyung Hee University, 24, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Jee W; College of Korean Medicine, Kyung Hee University, 24, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Park SM; College of Korean Medicine, Kyung Hee University, 24, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Kim SW; College of Korean Medicine, Kyung Hee University, 24, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Jung JH; College of Korean Medicine, Kyung Hee University, 24, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.
Kim H; College of Korean Medicine, Kyung Hee University, 24, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.; Department of Korean Rehabilitation Medicine, Kyung Hee University Medical Center, Seoul 02447, Republic of Korea.
Kim KI; College of Korean Medicine, Kyung Hee University, 24, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.; Division of Allergy, Immune and Respiratory System, Department of Internal Medicine, College of Korean Medicine, Kyung Hee Medical Center, Kyung Hee University, Seoul 02447, Republic of Korea.
Jang HJ; College of Korean Medicine, Kyung Hee University, 24, Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea.; Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 18; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:: Journal Article
MeSH Terms:: Signal Transduction*
Colonic Neoplasms*/drug therapy
Colonic Neoplasms*/metabolism
Humans ; Proto-Oncogene Proteins c-myc/genetics ; Proto-Oncogene Proteins c-myc/metabolism ; Cell Cycle Checkpoints ; Apoptosis ; Fluorouracil/pharmacology ; Mitosis ; Cell Proliferation ; Cell Line, Tumor ; Repressor Proteins/genetics

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Skocz do pozycji: 19.

Tytuł:: Cytotoxicity and Radiosensitizing Potentials of Pilosulin-3, a Recombinant Ant Venom, in Breast Cancer Cells.
Autorzy:: Alzeer RM; Department of Zoology, College of Science, King Saud University, Riyadh 11541, Saudi Arabia.
Al-Hadyan KS; Biomedical Physics Department, Radiation Biology Section, King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia.
Al-Harbi NM; Biomedical Physics Department, Radiation Biology Section, King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia.
Bin Judia SS; Biomedical Physics Department, Radiation Biology Section, King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia.
Almeer RS; Department of Zoology, College of Science, King Saud University, Riyadh 11541, Saudi Arabia.
Alsbeih GA; Biomedical Physics Department, Radiation Biology Section, King Faisal Specialist Hospital & Research Centre, Riyadh 11211, Saudi Arabia.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2023 Dec 15; Vol. 15 (12). Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:: Journal Article
MeSH Terms:: Ant Venoms*
Breast Neoplasms*/drug therapy
Breast Neoplasms*/radiotherapy
Humans ; Female ; Apoptosis ; Australia ; Cell Line, Tumor ; G2 Phase Cell Cycle Checkpoints ; Peptides

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Skocz do pozycji: 20.

Tytuł:: Pigmented Microbial Extract (PMB) from Exiguobacterium Species MB2 Strain (PMB1) and Bacillus subtilis Strain MB1 (PMB2) Inhibited Breast Cancer Cells Growth In Vivo and In Vitro.
Autorzy:: Bandi DR; Department of Applied Microbiology, Sri Padmavathi Mahila Viswavidyalayam, Tirupati 517502, Andhra Pradesh, India.
Chitturi CMK; Department of Applied Microbiology, Sri Padmavathi Mahila Viswavidyalayam, Tirupati 517502, Andhra Pradesh, India.
Aswathanarayan JB; Department of Microbiology, JSS Academy of Higher Education & Research (JSS AHER), Mysore 570015, Karnataka, India.
Veeresh PKM; Center of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research (JSS AHER), Mysore 570015, Karnataka, India.
Bovilla VR; Center of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research (JSS AHER), Mysore 570015, Karnataka, India.
Sukocheva OA; Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.
Devi PS; Department of Applied Microbiology, Sri Padmavathi Mahila Viswavidyalayam, Tirupati 517502, Andhra Pradesh, India.
Natraj SM; Center of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research (JSS AHER), Mysore 570015, Karnataka, India.
Madhunapantula SV; Center of Excellence in Molecular Biology and Regenerative Medicine (CEMR) Laboratory, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research (JSS AHER), Mysore 570015, Karnataka, India.; Special Interest Group (SIG) in Cancer Biology and Cancer Stem Cells (CBCSC), JSS Academy of Higher Education & Research (JSS AHER), Mysore 570015, Karnataka, India.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 12; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 12.
Typ publikacji:: Journal Article
MeSH Terms:: Breast Neoplasms*/metabolism
Triple Negative Breast Neoplasms*
Humans ; Female ; Animals ; Mice ; Bacillus subtilis ; Exiguobacterium ; Cell Cycle Checkpoints ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Cell Proliferation ; Cell Line, Tumor ; Apoptosis ; Tumor Microenvironment

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