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Wyszukujesz frazę ""Cell Death"" wg kryterium: Temat


Tytuł:
Yersinia interactions with regulated cell death pathways.
Autorzy:
Chen KW; Immunology Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.
Brodsky IE; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, United States; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, United States. Electronic address: .
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Źródło:
Current opinion in microbiology [Curr Opin Microbiol] 2023 Feb; Vol. 71, pp. 102256. Date of Electronic Publication: 2022 Dec 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Regulated Cell Death*
Yersinia Infections*
Humans ; Animals ; Yersinia ; Type III Secretion Systems/metabolism ; Cell Death ; Signal Transduction ; Bacterial Proteins
Czasopismo naukowe
Tytuł:
Research progress in inducing immunogenic cell death of tumor cells.
Autorzy:
Xie D; Department of Urology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Wang Q; Department of Urology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Wu G; Department of Urology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Nov 17; Vol. 13, pp. 1017400. Date of Electronic Publication: 2022 Nov 17 (Print Publication: 2022).
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Regulated Cell Death*
Drug-Related Side Effects and Adverse Reactions*
Humans ; Immunogenic Cell Death ; Cell Count ; Alarmins
Czasopismo naukowe
Tytuł:
Discovery of the first PD-1 ligand encoded by a pathogen.
Autorzy:
Martínez-Vicente P; Unitat d'Immunologia, Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Poblador F; Unitat d'Immunologia, Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Leitner J; Division of Immune Receptor and T-Cell Activation, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Farré D; Unitat d'Immunologia, Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Steinberger P; Division of Immune Receptor and T-Cell Activation, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Engel P; Unitat d'Immunologia, Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Angulo A; Unitat d'Immunologia, Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Sep 13; Vol. 13, pp. 1007334. Date of Electronic Publication: 2022 Sep 13 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
B7-H1 Antigen*/metabolism
Programmed Cell Death 1 Ligand 2 Protein*/metabolism
DNA ; Ligands ; Membrane Glycoproteins/metabolism ; Programmed Cell Death 1 Receptor/genetics ; Viral Proteins
Czasopismo naukowe
Tytuł:
Population pharmacokinetics and exposure-response of anti-programmed cell death protein-1 monoclonal antibody dostarlimab in advanced solid tumours.
Autorzy:
Melhem M; GlaxoSmithKline, Waltham, MA, USA.
Hanze E; qPharmetra, Cary, NC, USA.
Lu S; GlaxoSmithKline, Waltham, MA, USA.; Scholar Rock, Cambridge, MA, USA.
Alskär O; qPharmetra, Cary, NC, USA.
Visser S; GlaxoSmithKline, Collegeville, PA, USA.
Gandhi Y; GlaxoSmithKline, Collegeville, PA, USA.
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Źródło:
British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 Sep; Vol. 88 (9), pp. 4142-4154. Date of Electronic Publication: 2022 Apr 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/drug therapy
Neoplasms*/pathology
Programmed Cell Death 1 Receptor*/therapeutic use
Albumins ; Antibodies, Monoclonal ; Antibodies, Monoclonal, Humanized ; Body Weight ; Cell Death ; Clinical Trials, Phase I as Topic ; Humans ; Models, Biological
Czasopismo naukowe
Tytuł:
PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability.
Autorzy:
Hurrell BP; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Helou DG; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Howard E; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Painter JD; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Shafiei-Jahani P; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Sharpe AH; Department of Immunology, Harvard Medical School, Boston, MA, USA.
Akbari O; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. .
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Źródło:
Nature communications [Nat Commun] 2022 Aug 31; Vol. 13 (1), pp. 5118. Date of Electronic Publication: 2022 Aug 31.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Forkhead Transcription Factors*/metabolism
Programmed Cell Death 1 Ligand 2 Protein*/metabolism
T-Lymphocytes, Regulatory*/metabolism
Animals ; Interleukin-10/genetics ; Interleukin-10/metabolism ; Mice ; Ovalbumin ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/metabolism
Czasopismo naukowe
Tytuł:
Schweinfurthin induces ICD without ER stress and caspase activation.
Autorzy:
Zhang R; Department of Medicine, Penn State College of Medicine, Hershey, PA, USA.; Department of Pharmacology, Penn State College of Medicine, Hershey, PA, USA.; Penn State Cancer Institute, Hershey, PA, USA.; Department of Microbiology and Immunology, Penn State College of Medicine, Hershey, PA, USA.
Neighbors JD; Department of Medicine, Penn State College of Medicine, Hershey, PA, USA.; Department of Pharmacology, Penn State College of Medicine, Hershey, PA, USA.; Penn State Cancer Institute, Hershey, PA, USA.
Schell TD; Penn State Cancer Institute, Hershey, PA, USA.; Department of Microbiology and Immunology, Penn State College of Medicine, Hershey, PA, USA.
Hohl RJ; Department of Medicine, Penn State College of Medicine, Hershey, PA, USA.; Department of Pharmacology, Penn State College of Medicine, Hershey, PA, USA.; Penn State Cancer Institute, Hershey, PA, USA.
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Źródło:
Oncoimmunology [Oncoimmunology] 2022 Aug 03; Vol. 11 (1), pp. 2104551. Date of Electronic Publication: 2022 Aug 03 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Immunogenic Cell Death*
Neoplasms*
Animals ; Apoptosis ; Caspases/pharmacology ; Cell Death ; Mice
Czasopismo naukowe
Tytuł:
Regulated cell death (RCD) in cancer: key pathways and targeted therapies.
Autorzy:
Peng F; West China School of Pharmacy, State Key Laboratory of Biotherapy and Cancer Center, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.
Liao M; West China School of Pharmacy, State Key Laboratory of Biotherapy and Cancer Center, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.
Qin R; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Zhu S; West China School of Pharmacy, State Key Laboratory of Biotherapy and Cancer Center, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
Peng C; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Fu L; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China. leilei_.
Chen Y; West China School of Pharmacy, State Key Laboratory of Biotherapy and Cancer Center, Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China. .
Han B; State Key Laboratory of Southwestern Chinese Medicine Resources, Hospital of Chengdu University of Traditional Chinese Medicine, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. .
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Źródło:
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2022 Aug 13; Vol. 7 (1), pp. 286. Date of Electronic Publication: 2022 Aug 13.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/drug therapy
Neoplasms*/genetics
Regulated Cell Death*/genetics
Apoptosis ; Cell Death ; Humans ; Signal Transduction
Czasopismo naukowe
Tytuł:
Anastasis: cell recovery mechanisms and potential role in cancer.
Autorzy:
Mohammed RN; Medical Laboratory Analysis Department, College of Health Sciences, Cihan University of Sulaimaniya, Kurdistan Region, Sulaimaniya, Iraq.; College of Veterinary Medicine, University of Sulaimani, Sulaimaniyah, Iraq.
Khosravi M; Department of Psychiatry and Clinical Psychology, Zahedan University of Medical Sciences, Zahedan, Iran.
Rahman HS; Department of Physiology, College of Medicine, University of Sulaimani, Sulaimaniyah, Iraq.; Department of Medical Laboratory Sciences, Komar University of Science and Technology, Sarchinar District, Sulaimaniyah, Iraq.
Adili A; Department of Oncology, Tabriz University of Medical Sciences, Tabriz, Iran.
Kamali N; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Soloshenkov PP; I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia. .
Thangavelu L; Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai, India.
Saeedi H; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Shomali N; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Tamjidifar R; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Isazadeh A; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Aslaminabad R; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Akbari M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2022 Jun 03; Vol. 20 (1), pp. 81. Date of Electronic Publication: 2022 Jun 03.
Typ publikacji:
Journal Article; Review; Video-Audio Media
MeSH Terms:
Cell Death Reversal*
Neoplasms*/metabolism
Apoptosis ; Cell Death ; Cell Survival ; DNA Damage ; Humans
Czasopismo naukowe
Tytuł:
PKHB1, a thrombospondin-1 peptide mimic, induces anti-tumor effect through immunogenic cell death induction in breast cancer cells.
Autorzy:
Calvillo-Rodríguez KM; Facultad de Ciencias Biologicas, Laboratorio de Inmunología y Virología, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Mexico.; Sorbonne Université, Ecole Normale Supérieure, PSL University, CNRS, Laboratoire des Biomolécules, LBM, 75005 Paris, France.; Sorbonne Université, Ecole Normale Supérieure, PSL University, CNRS, Laboratoire des Biomolécules, DRUG Lab, Site OncoDesign, 25-27 Avenue du Québec, 91140 Les Ulis, France.
Mendoza-Reveles R; Facultad de Ciencias Biologicas, Laboratorio de Inmunología y Virología, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Mexico.
Gómez-Morales L; Facultad de Ciencias Biologicas, Laboratorio de Inmunología y Virología, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Mexico.; Sorbonne Université, Ecole Normale Supérieure, PSL University, CNRS, Laboratoire des Biomolécules, LBM, 75005 Paris, France.; Sorbonne Université, Ecole Normale Supérieure, PSL University, CNRS, Laboratoire des Biomolécules, DRUG Lab, Site OncoDesign, 25-27 Avenue du Québec, 91140 Les Ulis, France.; Kaybiotix, GmbH, Zugerstrasse 32, 6340 Baar, Switzerland.
Uscanga-Palomeque AC; Facultad de Ciencias Biologicas, Laboratorio de Inmunología y Virología, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Mexico.
Karoyan P; Sorbonne Université, Ecole Normale Supérieure, PSL University, CNRS, Laboratoire des Biomolécules, LBM, 75005 Paris, France.; Sorbonne Université, Ecole Normale Supérieure, PSL University, CNRS, Laboratoire des Biomolécules, DRUG Lab, Site OncoDesign, 25-27 Avenue du Québec, 91140 Les Ulis, France.; Kaybiotix, GmbH, Zugerstrasse 32, 6340 Baar, Switzerland.; Kayvisa, AG, Industriestrasse, 44, 6300 Zug, Switzerland.; χ-Pharma, 25 Avenue du Québec, 91140 Les Ulis, France.
Martínez-Torres AC; Facultad de Ciencias Biologicas, Laboratorio de Inmunología y Virología, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Mexico.
Rodríguez-Padilla C; Facultad de Ciencias Biologicas, Laboratorio de Inmunología y Virología, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Mexico.; LONGEVEDEN SA de CV, Monterrey, Mexico.
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Źródło:
Oncoimmunology [Oncoimmunology] 2022 Apr 04; Vol. 11 (1), pp. 2054305. Date of Electronic Publication: 2022 Apr 04 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/metabolism
Immunogenic Cell Death*
Cell Death ; Cell Line, Tumor ; Female ; Humans ; Peptides/pharmacology
Czasopismo naukowe
Tytuł:
The Achilles' heel of cancer: targeting tumors via lysosome-induced immunogenic cell death.
Autorzy:
Iulianna T; Odin Therapeutics, Newton, MA, 02458, USA. .; Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. .
Kuldeep N; Odin Therapeutics, Newton, MA, 02458, USA.
Eric F; Odin Therapeutics, Newton, MA, 02458, USA.
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Źródło:
Cell death & disease [Cell Death Dis] 2022 May 30; Vol. 13 (5), pp. 509. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Immunogenic Cell Death*
Neoplasms*/pathology
Cell Death/physiology ; Humans ; Immunotherapy ; Lysosomes/metabolism
Czasopismo naukowe
Tytuł:
Innate immunity in fungi: Is regulated cell death involved?
Autorzy:
Gaspar ML; School of Integrative Plant Science, Cornell University, Ithaca, New York, United States of America.
Pawlowska TE; School of Integrative Plant Science, Cornell University, Ithaca, New York, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2022 May 19; Vol. 18 (5), pp. e1010460. Date of Electronic Publication: 2022 May 19 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Immunity, Innate*
Regulated Cell Death*
Cell Death ; Fungi
Czasopismo naukowe
Tytuł:
Clinical relevance of PD-L2 expression in surgically resected lung adenocarcinoma.
Autorzy:
Takamochi K; Department of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan. Electronic address: .
Hara K; Department of Human Pathology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hayashi T; Department of Human Pathology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kohsaka S; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan.
Takahashi F; Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Suehara Y; Department of Orthopedic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Shimokawa M; Department of Biostatistics, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Suzuki K; Department of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
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Źródło:
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2022 Jun; Vol. 168, pp. 50-58. Date of Electronic Publication: 2022 Apr 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma*/genetics
Adenocarcinoma*/metabolism
Adenocarcinoma*/surgery
Adenocarcinoma of Lung*/genetics
Adenocarcinoma of Lung*/surgery
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/surgery
Programmed Cell Death 1 Ligand 2 Protein/*metabolism
B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Biomarkers, Tumor/metabolism ; ErbB Receptors/metabolism ; Humans ; Male ; Neoplasm Recurrence, Local ; Programmed Cell Death 1 Receptor/metabolism ; Protein-Tyrosine Kinases/genetics ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism ; Receptor Protein-Tyrosine Kinases/genetics
Czasopismo naukowe
Tytuł:
Apoptosis, autophagic cell death, and necroptosis: different types of programmed cell death in bovine corpus luteum regression.
Autorzy:
Hojo T; Division of Livestock and Grassland Research, Kyushu Okinawa Agricultural Research Center, NARO, Kumamoto 861-1192, Japan.
Skarzynski DJ; Department of Reproductive Immunology and Pathology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.
Okuda K; Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Japan.
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Źródło:
The Journal of reproduction and development [J Reprod Dev] 2022 Dec 19; Vol. 68 (6), pp. 355-360. Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Luteolysis*/physiology
Autophagic Cell Death*
Pregnancy ; Female ; Cattle ; Animals ; Necroptosis ; Endothelial Cells ; Dinoprost/metabolism ; Corpus Luteum/metabolism ; Apoptosis/physiology ; Mammals
Czasopismo naukowe
Tytuł:
Discovery of small-molecule PD-1/PD-L1 antagonists through combined virtual screening and experimental validation.
Autorzy:
DiFrancesco M; NanoBio Laboratory, School of Engineering, Widener University, Chester, PA, USA.
Hofer J; Department of Computer Science, Widener University, Chester, PA, USA.
Aradhya A; Department of Computer Science, Widener University, Chester, PA, USA.
Rufinus J; Department of Computer Science, Widener University, Chester, PA, USA.
Stoddart J; Department of Computer Science, Widener University, Chester, PA, USA.
Finocchiaro S; NanoBio Laboratory, School of Engineering, Widener University, Chester, PA, USA.
Mani J; NanoBio Laboratory, School of Engineering, Widener University, Chester, PA, USA.
Tevis S; NanoBio Laboratory, School of Engineering, Widener University, Chester, PA, USA.
Visconti M; NanoBio Laboratory, School of Engineering, Widener University, Chester, PA, USA.
Walawender G; NanoBio Laboratory, School of Engineering, Widener University, Chester, PA, USA.
DiFlumeri J; NanoBio Laboratory, School of Engineering, Widener University, Chester, PA, USA.
Fattakhova E; NanoBio Laboratory, School of Engineering, Widener University, Chester, PA, USA.
Patil SP; NanoBio Laboratory, School of Engineering, Widener University, Chester, PA, USA. Electronic address: .
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Źródło:
Computational biology and chemistry [Comput Biol Chem] 2023 Feb; Vol. 102, pp. 107804. Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Molecular Dynamics Simulation*
Programmed Cell Death 1 Receptor*/chemistry
Programmed Cell Death 1 Receptor*/metabolism
Humans ; High-Throughput Screening Assays ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł:
Reduction-triggered polycyclodextrin supramolecular nanocage induces immunogenic cell death for improved chemotherapy.
Autorzy:
Hu J; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Materials and Energy & Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing 400715, PR China.
Liang M; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Materials and Energy & Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing 400715, PR China.
Ye M; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Materials and Energy & Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing 400715, PR China.
Xu J; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Materials and Energy & Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing 400715, PR China.
Liu H; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Materials and Energy & Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing 400715, PR China.
Zhang X; Pediatric Research Institute, Department of Hematology and Oncology, Shenzhen Children's Hospital, Shenzhen, Guangdong 518038, PR China. Electronic address: .
Sun W; Key Laboratory of Laser Technology and Optoelectronic Functional Materials of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, PR China.
Xue P; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Materials and Energy & Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing 400715, PR China.
Kang Y; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Materials and Energy & Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing 400715, PR China. Electronic address: .
Xu Z; Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Materials and Energy & Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing 400715, PR China; Key Laboratory of Laser Technology and Optoelectronic Functional Materials of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, PR China. Electronic address: .
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Źródło:
Carbohydrate polymers [Carbohydr Polym] 2023 Feb 01; Vol. 301 (Pt B), pp. 120365. Date of Electronic Publication: 2022 Nov 17.
Typ publikacji:
Journal Article
MeSH Terms:
Immunogenic Cell Death*
Drug Delivery Systems*
Doxorubicin/pharmacology ; Tumor Microenvironment ; Glutathione
Czasopismo naukowe
Tytuł:
Polystyrene microplastic particles induce autophagic cell death in BEAS-2B human bronchial epithelial cells.
Autorzy:
Jeon MS; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Kim JW; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Han YB; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Jeong MH; Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Kim HR; College of Pharmacy, Daegu Catholic University, Gyeongsan, Republic of Korea.
Sik Kim H; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
Park YJ; College of Pharmacy, Kyungsung University, Busan, Republic of Korea.
Chung KH; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea.
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Źródło:
Environmental toxicology [Environ Toxicol] 2023 Feb; Vol. 38 (2), pp. 359-367. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Polystyrenes*/toxicity
Autophagic Cell Death*
Animals ; Humans ; Microplastics/toxicity ; Plastics/toxicity ; Reactive Oxygen Species ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
mTOR regulates T cell exhaustion and PD-1-targeted immunotherapy response during chronic viral infection.
Autorzy:
Ando S; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Perkins CM; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Sajiki Y; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Chastain C; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Valanparambil RM; Emory Vaccine Center.; Depatment of Microbiology and Immunology, and.
Wieland A; Emory Vaccine Center.; Depatment of Microbiology and Immunology, and.
Hudson WH; Emory Vaccine Center.; Depatment of Microbiology and Immunology, and.
Hashimoto M; Emory Vaccine Center.; Depatment of Microbiology and Immunology, and.
Ramalingam SS; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, Georgia, USA.; Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Ahmed R; Emory Vaccine Center.; Depatment of Microbiology and Immunology, and.; Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Araki K; Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
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Źródło:
The Journal of clinical investigation [J Clin Invest] 2023 Jan 17; Vol. 133 (2). Date of Electronic Publication: 2023 Jan 17.
Typ publikacji:
Journal Article
MeSH Terms:
Programmed Cell Death 1 Receptor*/genetics
Programmed Cell Death 1 Receptor*/metabolism
Virus Diseases*/metabolism
CD8-Positive T-Lymphocytes/metabolism ; Hepatitis A Virus Cellular Receptor 2/genetics ; Hepatitis A Virus Cellular Receptor 2/metabolism ; Immunotherapy ; Persistent Infection ; T-Cell Exhaustion ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
PD-1/PD-L1 blockade is a potent adjuvant in treatment of Staphylococcus aureus osteomyelitis in mice.
Autorzy:
Li K; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China.
Chen Y; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China.
Lin Y; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China.
Zhang G; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China.
Su J; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China.
Wu X; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China.
Cheng C; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China.
Wang Y; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China.
Yu B; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China. Electronic address: .
Zhang X; Division of Orthopedics and Traumatology, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China; Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No.1838 North of Guangzhou Avenue, Guangzhou, Guangdong Province 510515, China. Electronic address: .
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Źródło:
Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2023 Jan 04; Vol. 31 (1), pp. 174-192. Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
B7-H1 Antigen*/antagonists & inhibitors
B7-H1 Antigen*/genetics
Osteomyelitis*/metabolism
Osteomyelitis*/therapy
Programmed Cell Death 1 Receptor*/antagonists & inhibitors
Programmed Cell Death 1 Receptor*/genetics
Antibodies*/therapeutic use
Animals ; Mice ; Adjuvants, Immunologic ; Staphylococcus aureus ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
The Potential Role of Regulated Cell Death in Dry Eye Diseases and Ocular Surface Dysfunction.
Autorzy:
Scarpellini C; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2160 Antwerp, Belgium.
Ramos Llorca A; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2160 Antwerp, Belgium.
Lanthier C; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2160 Antwerp, Belgium.
Klejborowska G; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2160 Antwerp, Belgium.
Augustyns K; Laboratory of Medicinal Chemistry, University of Antwerp, Universiteitsplein 1, B-2160 Antwerp, Belgium.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 01; Vol. 24 (1). Date of Electronic Publication: 2023 Jan 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Dry Eye Syndromes*/metabolism
Regulated Cell Death*
Humans ; Inflammation ; Apoptosis ; Oxidative Stress
Czasopismo naukowe
Tytuł:
Identification, binding, and structural characterization of single domain anti-PD-L1 antibodies inhibitory of immune regulatory proteins PD-1 and CD80.
Autorzy:
Kang-Pettinger T; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, Henry Wellcome Building, University of Leicester, Leicester, UK.
Walker K; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, Henry Wellcome Building, University of Leicester, Leicester, UK.
Brown R; LifeArc, Centre for Therapeutics Discovery, Open Innovation Campus, Stevenage, UK.
Cowan R; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, Henry Wellcome Building, University of Leicester, Leicester, UK.
Wright H; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, Henry Wellcome Building, University of Leicester, Leicester, UK.
Baravalle R; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, Henry Wellcome Building, University of Leicester, Leicester, UK.
Waters LC; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, Henry Wellcome Building, University of Leicester, Leicester, UK.
Muskett FW; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, Henry Wellcome Building, University of Leicester, Leicester, UK.
Bowler MW; European Molecular Biology Laboratory, Grenoble, France.
Sawmynaden K; LifeArc, Centre for Therapeutics Discovery, Open Innovation Campus, Stevenage, UK.
Coombs PJ; LifeArc, Centre for Therapeutics Discovery, Open Innovation Campus, Stevenage, UK.
Carr MD; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, Henry Wellcome Building, University of Leicester, Leicester, UK. Electronic address: .
Hall G; Leicester Institute of Structural and Chemical Biology and Department of Molecular and Cell Biology, Henry Wellcome Building, University of Leicester, Leicester, UK. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Jan; Vol. 299 (1), pp. 102769. Date of Electronic Publication: 2022 Dec 05.
Typ publikacji:
Journal Article
MeSH Terms:
B7-1 Antigen*/metabolism
B7-H1 Antigen*/genetics
B7-H1 Antigen*/metabolism
Programmed Cell Death 1 Receptor*/metabolism
Antibodies*/chemistry
Antibodies*/metabolism
Humans ; Neoplasms/therapy ; Protein Binding ; Binding Sites ; Crystallography
Czasopismo naukowe

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