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Wyszukujesz frazę ""Cell Differentiation"" wg kryterium: Temat


Tytuł:
Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer.
Autorzy:
Zhou P; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Shi H; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Huang H; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Sun X; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Yuan S; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Chapman NM; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Connelly JP; Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN, USA.
Lim SA; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Saravia J; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Kc A; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Pruett-Miller SM; Center for Advanced Genome Engineering, St. Jude Children's Research Hospital, Memphis, TN, USA.
Chi H; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA. .
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Źródło:
Nature [Nature] 2023 Dec; Vol. 624 (7990), pp. 154-163. Date of Electronic Publication: 2023 Nov 15.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*/drug effects
Cell Differentiation*/genetics
Clustered Regularly Interspaced Short Palindromic Repeats*/genetics
Gene Editing*
Mutagenesis*
Neoplasms*/genetics
Neoplasms*/immunology
Single-Cell Analysis*/methods
T-Lymphocytes, Cytotoxic*/cytology
T-Lymphocytes, Cytotoxic*/drug effects
T-Lymphocytes, Cytotoxic*/immunology
T-Lymphocytes, Cytotoxic*/metabolism
Humans ; Immune Checkpoint Inhibitors/immunology ; Immune Checkpoint Inhibitors/pharmacology
Czasopismo naukowe
Tytuł:
Phosphorylation of hnRNP A1-Serine 199 Is Not Required for T Cell Differentiation and Function.
Autorzy:
White TLA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Jin Y; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Roberts SDA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Gable MJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Morel PA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
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Źródło:
ImmunoHorizons [Immunohorizons] 2024 Feb 01; Vol. 8 (2), pp. 136-146.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*
Heterogeneous Nuclear Ribonucleoprotein A1*/metabolism
T-Lymphocytes*/cytology
Animals ; Mice ; Phosphorylation ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Antigen, T-Cell/metabolism ; Serine/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł:
MCP-5 suppresses osteoclast differentiation through Ccr5 upregulation.
Autorzy:
Kim JH; Department of Pharmacology, Chonnam National University Medical School, Gwangju, Republic of Korea.; Hard-Tissue Biointerface Research Center, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.
Kim K; Department of Pharmacology, Chonnam National University Medical School, Gwangju, Republic of Korea.
Kim I; Department of Pharmacology, Chonnam National University Medical School, Gwangju, Republic of Korea.
Seong S; Department of Pharmacology, Chonnam National University Medical School, Gwangju, Republic of Korea.; Hard-Tissue Biointerface Research Center, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.
Koh JT; Hard-Tissue Biointerface Research Center, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.; Department of Pharmacology and Dental Therapeutics, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.
Kim N; Department of Pharmacology, Chonnam National University Medical School, Gwangju, Republic of Korea.; Hard-Tissue Biointerface Research Center, School of Dentistry, Chonnam National University, Gwangju, Republic of Korea.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2024 Feb; Vol. 239 (2), pp. e31171. Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*/physiology
Membrane Glycoproteins*/metabolism
Osteoclasts*/cytology
Osteoclasts*/metabolism
Animals ; Humans ; Mice ; NF-kappa B/metabolism ; RANK Ligand/pharmacology ; RANK Ligand/metabolism ; Receptor Activator of Nuclear Factor-kappa B/metabolism ; Up-Regulation ; Mice, Inbred ICR ; Male ; Monocyte Chemoattractant Proteins/genetics ; Monocyte Chemoattractant Proteins/metabolism ; Monocyte Chemoattractant Proteins/pharmacology ; Cells, Cultured
Czasopismo naukowe
Tytuł:
The transcription factor ZEB2 drives the formation of age-associated B cells.
Autorzy:
Dai D; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Renji Hospital, SJTUSM, Shanghai, China.
Gu S; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.
Han X; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.
Ding H; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.
Jiang Y; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.
Zhang X; Shanghai Key Laboratory of Maternal and Fetal Medicine, Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai, China.; Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, China.
Yao C; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Hong S; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.
Zhang J; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Shen Y; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.
Hou G; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.
Qu B; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.
Zhou H; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.
Qin Y; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.
He Y; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.
Ma J; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.
Yin Z; Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, China.
Ye Z; Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, China.
Qian J; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.
Jiang Q; Department of Medical Genetics, Capital Institute of Pediatrics, Beijing, China.
Wu L; Department of Medical Genetics, Capital Institute of Pediatrics, Beijing, China.
Guo Q; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.
Chen S; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.
Huang C; Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, SJTUSM, Shanghai, China.
Kottyan LC; Center of Autoimmune Genomics and Etiology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.
Weirauch MT; Center of Autoimmune Genomics and Etiology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.
Vinuesa CG; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.; Francis Crick Institute, London, UK.
Shen N; Shanghai Institute of Rheumatology, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine (SJTUSM), Shanghai, China.; Centre for Personalised Immunology (CACPI), Shanghai Renji Hospital, SJTUSM, Shanghai, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Renji Hospital, SJTUSM, Shanghai, China.; Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, China.; Center of Autoimmune Genomics and Etiology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Jan 26; Vol. 383 (6681), pp. 413-421. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Autoimmunity*/genetics
B-Lymphocytes*/cytology
B-Lymphocytes*/metabolism
Cell Differentiation*/genetics
Gene Expression Regulation*
Lupus Erythematosus, Systemic*/genetics
Lupus Erythematosus, Systemic*/immunology
Zinc Finger E-box Binding Homeobox 2*/genetics
Zinc Finger E-box Binding Homeobox 2*/metabolism
Animals ; Humans ; Mice ; Cell Lineage/genetics ; MEF2 Transcription Factors/genetics ; MEF2 Transcription Factors/metabolism ; Haploinsufficiency ; Aging/immunology ; Disease Models, Animal ; Female
Czasopismo naukowe
Tytuł:
Role of connexin 32 in the directional differentiation of induced pluripotent stem cells into hepatocytes.
Autorzy:
Xu Y; Department of General Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China.
Wang Y; Department of General Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China.
Qi R; Department of General Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China.
Li K; Department of General Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China.
Wang X; Department of Ultrasonography, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China.
Li X; Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, 97239, USA.
Shi B; Department of General Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, 200065, China.; Department of General Surgery, Xinhua Hospital, School of medicine, Shanghai Jiaotong University, 200025, China.
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Źródło:
International journal of medical sciences [Int J Med Sci] 2024 Jan 12; Vol. 21 (3), pp. 508-518. Date of Electronic Publication: 2024 Jan 12 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*
Gap Junction beta-1 Protein*/genetics
Hepatocytes*/cytology
Induced Pluripotent Stem Cells*/cytology
Down-Regulation ; Vitamin K 2 ; Humans
Czasopismo naukowe
Tytuł:
The ATF4-regulated LncRNA MALAT1 promotes odontoblastic differentiation of human dental pulp stem cells via histone demethylase JMJD3: An in vitro study.
Autorzy:
Yu S; Liaoning Provincial Key Laboratory of Oral Disease, School and Hospital of Stomatology, China Medical University, Shenyang, China.; Department of Oral Medicine, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Guo J; Liaoning Provincial Key Laboratory of Oral Disease, School and Hospital of Stomatology, China Medical University, Shenyang, China.
Yang D; Liaoning Provincial Key Laboratory of Oral Disease, School and Hospital of Stomatology, China Medical University, Shenyang, China.
Yan X; Liaoning Provincial Key Laboratory of Oral Disease, School and Hospital of Stomatology, China Medical University, Shenyang, China.
Zhang Z; Liaoning Provincial Key Laboratory of Oral Disease, School and Hospital of Stomatology, China Medical University, Shenyang, China.
Wei P; Liaoning Provincial Key Laboratory of Oral Disease, School and Hospital of Stomatology, China Medical University, Shenyang, China.
Qiu L; Liaoning Provincial Key Laboratory of Oral Disease, School and Hospital of Stomatology, China Medical University, Shenyang, China.
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Źródło:
International endodontic journal [Int Endod J] 2024 Jan; Vol. 57 (1), pp. 50-63. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*
Odontoblasts*
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Jumonji Domain-Containing Histone Demethylases*/genetics
Jumonji Domain-Containing Histone Demethylases*/metabolism
Humans ; Activating Transcription Factor 4/metabolism ; Cells, Cultured ; Dental Pulp ; Extracellular Matrix Proteins/genetics ; Extracellular Matrix Proteins/metabolism ; Histone Demethylases/metabolism ; Histones/metabolism ; Stem Cells
Czasopismo naukowe
Tytuł:
Macroevolution, differentiation trees, and the growth of coding systems.
Autorzy:
Igamberdiev AU; Department of Biology, Memorial University of Newfoundland, St. John's, NL, Canada. Electronic address: .
Gordon R; Gulf Specimen Marine Laboratory & Aquarium, 222 Clark Drive, Panacea, FL, 32346, USA. Electronic address: .
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Źródło:
Bio Systems [Biosystems] 2023 Dec; Vol. 234, pp. 105044. Date of Electronic Publication: 2023 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*/genetics
Morphogenesis/genetics ; Phylogeny
Czasopismo naukowe
Tytuł:
Reversible Differentiation of Melanocyte Stem Cells: Designed to Last or Be Lost?
Autorzy:
Sun Q; Ronald O. Perelman Department of Dermatology, School of Medicine, New York University, New York, USA; Department of Cell Biology, School of Medicine, New York University, New York, USA.
Brinks A; Ronald O. Perelman Department of Dermatology, School of Medicine, New York University, New York, USA; Department of Cell Biology, School of Medicine, New York University, New York, USA.
Ito M; Ronald O. Perelman Department of Dermatology, School of Medicine, New York University, New York, USA; Department of Cell Biology, School of Medicine, New York University, New York, USA. Electronic address: .
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Źródło:
The Journal of investigative dermatology [J Invest Dermatol] 2023 Dec; Vol. 143 (12), pp. 2343-2345. Date of Electronic Publication: 2023 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*
Melanocytes*/cytology
Stem Cells*/cytology
Czasopismo naukowe
Tytuł:
OCT4 regulates WNT/β-catenin signaling and prevents mesoendoderm differentiation by repressing EOMES in porcine pluripotent stem cells.
Autorzy:
Xu T; Institute of Stem Cell and Regenerative Biology, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction (Huazhong Agricultural University), Ministry of Education, Wuhan, Hubei, China.
Su P; Institute of Stem Cell and Regenerative Biology, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction (Huazhong Agricultural University), Ministry of Education, Wuhan, Hubei, China.
Wu L; Institute of Stem Cell and Regenerative Biology, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction (Huazhong Agricultural University), Ministry of Education, Wuhan, Hubei, China.
Li D; Institute of Stem Cell and Regenerative Biology, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction (Huazhong Agricultural University), Ministry of Education, Wuhan, Hubei, China.
Qin W; Institute of Stem Cell and Regenerative Biology, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction (Huazhong Agricultural University), Ministry of Education, Wuhan, Hubei, China.
Li Q; Institute of Stem Cell and Regenerative Biology, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction (Huazhong Agricultural University), Ministry of Education, Wuhan, Hubei, China.
Zhou J; Institute of Stem Cell and Regenerative Biology, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction (Huazhong Agricultural University), Ministry of Education, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production (Huazhong Agricultural University), Ministry of Education, Wuhan, China.
Miao YL; Institute of Stem Cell and Regenerative Biology, College of Animal Science and Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction (Huazhong Agricultural University), Ministry of Education, Wuhan, Hubei, China.; Frontiers Science Center for Animal Breeding and Sustainable Production (Huazhong Agricultural University), Ministry of Education, Wuhan, China.; Hubei Hongshan Laboratory, Wuhan, China.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2023 Dec; Vol. 238 (12), pp. 2855-2866. Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*/genetics
Pluripotent Stem Cells*/cytology
Pluripotent Stem Cells*/metabolism
Wnt Signaling Pathway*/genetics
Animals ; beta Catenin/genetics ; beta Catenin/metabolism ; Chromatin/metabolism ; Swine ; T-Box Domain Proteins/metabolism ; Octamer Transcription Factor-3/metabolism ; Cell Line
Czasopismo naukowe
Tytuł:
Plant-derived nanovesicles: harnessing nature's power for tissue protection and repair.
Autorzy:
Chen X; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.; Department of Preventive Dentistry, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Xing X; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Lin S; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Huang L; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.; Department of Human Anatomy and Histology, and Embryology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China.
He L; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.; Department of Preventive Dentistry, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Zou Y; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.; Department of Preventive Dentistry, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Zhang X; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.; Department of Preventive Dentistry, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Su B; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China. .; Department of Preventive Dentistry, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China. .
Lu Y; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China. .; Department of Preventive Dentistry, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China. .
Zheng D; Fujian Key Laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2023 Nov 24; Vol. 21 (1), pp. 445. Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cell Differentiation*
Nanoparticles*
Plants*/chemistry
Lipid Bilayers
Czasopismo naukowe
Tytuł:
Transcriptional profiling of early differentiation of primary human mesenchymal stem cells into chondrocytes.
Autorzy:
Schwarzl T; European Molecular Biology Laboratory (EMBL), Meyerhofstraße 1, 69117, Heidelberg, Germany.
Keogh A; Previously: Regenerative Medicine Institute (REMEDI), Biosciences, National University of Ireland Galway, University Road, Galway, Ireland.
Shaw G; Regenerative Medicine Institute (REMEDI), Biosciences, National University of Ireland Galway, University Road, Galway, Ireland.
Krstic A; Systems Biology Ireland (SBI), School of Medicine, University College Dublin, Dublin, 4, Ireland.
Clayton E; Previously: Regenerative Medicine Institute (REMEDI), Biosciences, National University of Ireland Galway, University Road, Galway, Ireland.
Higgins DG; Systems Biology Ireland (SBI), School of Medicine, University College Dublin, Dublin, 4, Ireland.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD), Belfield, Dublin, 4, Ireland.
Kolch W; Systems Biology Ireland (SBI), School of Medicine, University College Dublin, Dublin, 4, Ireland. .; Conway Institute of Biomolecular and Biomedical Research, University College Dublin (UCD), Belfield, Dublin, 4, Ireland. .
Barry F; Regenerative Medicine Institute (REMEDI), Biosciences, National University of Ireland Galway, University Road, Galway, Ireland.
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Źródło:
Scientific data [Sci Data] 2023 Nov 03; Vol. 10 (1), pp. 758. Date of Electronic Publication: 2023 Nov 03.
Typ publikacji:
Dataset; Journal Article
MeSH Terms:
Cell Differentiation*
Chondrocytes*
Mesenchymal Stem Cells*
Humans ; Cartilage, Articular ; Transcriptome
Czasopismo naukowe
Tytuł:
Laminin fragments conjugated with perlecan's growth factor-binding domain differentiate human induced pluripotent stem cells into skin-derived precursor cells.
Autorzy:
Sugiyama-Nakagiri Y; Kao Corporation, 2602, Akabane Ichikai-Machi, Haga-gun, Tochigi, 321-3497, Japan. .
Yamashita S; Kao Corporation, 2602, Akabane Ichikai-Machi, Haga-gun, Tochigi, 321-3497, Japan.
Taniguchi Y; Division of Matrixome Research and Application, Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
Shimono C; Division of Matrixome Research and Application, Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
Sekiguchi K; Division of Matrixome Research and Application, Institute for Protein Research, Osaka University, Suita, Osaka, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 04; Vol. 13 (1), pp. 14556. Date of Electronic Publication: 2023 Sep 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*/drug effects
Heparan Sulfate Proteoglycans*/chemistry
Induced Pluripotent Stem Cells*/cytology
Induced Pluripotent Stem Cells*/drug effects
Intercellular Signaling Peptides and Proteins*/metabolism
Laminin*/chemistry
Laminin*/pharmacology
Peptide Fragments*/chemistry
Peptide Fragments*/pharmacology
Protein Domains*
Skin*/cytology
Humans ; Adipocytes/cytology ; Adipocytes/drug effects ; Osteocytes/cytology ; Osteocytes/drug effects ; Schwann Cells/cytology ; Schwann Cells/drug effects ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/pharmacology
Czasopismo naukowe
Tytuł:
Cell-connectivity-guided trajectory inference from single-cell data.
Autorzy:
Smolander J; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
Junttila S; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520 Turku, Finland.
Elo LL; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520 Turku, Finland.; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
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Źródło:
Bioinformatics (Oxford, England) [Bioinformatics] 2023 Sep 02; Vol. 39 (9).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*
Cluster Analysis
Czasopismo naukowe
Tytuł:
Organization of cortical microtubules in differentiated cells.
Autorzy:
Zhou P; Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China.
Yang G; Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China.
Xie W; Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, College of Life Sciences, Shandong Normal University, Jinan, China.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2023 Jun; Vol. 238 (6), pp. 1141-1147. Date of Electronic Publication: 2023 Apr 06.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*
Microtubules*/metabolism
Adherens Junctions ; Centrosome/metabolism ; Cytoskeleton
Czasopismo naukowe
Tytuł:
SDF-1 and NOTCH signaling in myogenic cell differentiation: the role of miRNA10a, 425, and 5100.
Autorzy:
Mierzejewski B; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Grabowska I; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Michalska Z; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Zdunczyk K; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Zareba F; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Irhashava A; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Chrzaszcz M; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Patrycy M; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Streminska W; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Janczyk-Ilach K; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Koblowska M; Laboratory of Systems Biology, Faculty of Biology, University of Warsaw, 02-096, Warsaw, Poland.; Laboratory of Microarray Analysis, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106, Warsaw, Poland.
Iwanicka-Nowicka R; Laboratory of Systems Biology, Faculty of Biology, University of Warsaw, 02-096, Warsaw, Poland.; Laboratory of Microarray Analysis, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106, Warsaw, Poland.
Gromadka A; Department of Bioinformatics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106, Warsaw, Poland.
Kowalski K; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Ciemerych MA; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland.
Brzoska E; Department of Cytology, Faculty of Biology, University of Warsaw, Miecznikowa 1 St, 02-096, Warsaw, Poland. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2023 Aug 15; Vol. 14 (1), pp. 204. Date of Electronic Publication: 2023 Aug 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*
Muscle, Skeletal*/metabolism
Satellite Cells, Skeletal Muscle*/metabolism
MicroRNAs*/genetics
Receptors, Notch*/metabolism
Chemokine CXCL12*/metabolism
Animals ; Mice ; Cell Movement ; Muscle Development/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł:
Mitochondrial integrated stress response controls lung epithelial cell fate.
Autorzy:
Han S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA. .
Lee M; Department of Life Science, Dongguk University-Seoul, Goyang-si, Republic of Korea.
Shin Y; Department of Life Science, Dongguk University-Seoul, Goyang-si, Republic of Korea.
Giovanni R; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Chakrabarty RP; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Herrerias MM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Dada LA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Flozak AS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Reyfman PA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Khuder B; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Reczek CR; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Gao L; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain.
Lopéz-Barneo J; Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain.
Gottardi CJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Budinger GRS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA.
Chandel NS; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University, Chicago, IL, USA. .; Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA. .
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Źródło:
Nature [Nature] 2023 Aug; Vol. 620 (7975), pp. 890-897. Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*/cytology
Alveolar Epithelial Cells*/metabolism
Alveolar Epithelial Cells*/pathology
Cell Differentiation*
Cell Lineage*
Lung*/cytology
Lung*/metabolism
Lung*/pathology
Mitochondria*/enzymology
Mitochondria*/metabolism
Stress, Physiological*
Animals ; Mice ; NAD/metabolism ; NADH Dehydrogenase/metabolism ; Protons ; RNA-Seq ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Single-Cell Gene Expression Analysis
Czasopismo naukowe
Tytuł:
Isolation and Differentiation of Neurons and Glial Cells from Olfactory Epithelium in Living Subjects.
Autorzy:
Unzueta-Larrinaga P; Department of Pharmacology, University of the Basque Country, UPV/EHU, Leioa, Spain.; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.
Barrena-Barbadillo R; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Department of Nursery, University of the Basque Country UPV/EHU, Leioa, Spain.
Ibarra-Lecue I; Department of Pharmacology, University of the Basque Country, UPV/EHU, Leioa, Spain.
Horrillo I; Department of Pharmacology, University of the Basque Country, UPV/EHU, Leioa, Spain.; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain.
Villate A; Department of Analytical Chemistry, University of the Basque Country UPV/EHU, Leioa, Spain.; PiE-UPV/EHU, Plentzia, ItsasEstazioa, Areatza Pasealekua, 48620, Plentzia, Spain.
Recio M; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Department of Psychiatry, Cruces University Hospital, Barakaldo, Spain.
Meana JJ; Department of Pharmacology, University of the Basque Country, UPV/EHU, Leioa, Spain.; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain.
Diez-Alarcia R; Department of Pharmacology, University of the Basque Country, UPV/EHU, Leioa, Spain.; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain.
Mentxaka O; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Department of Psychiatry, Cruces University Hospital, Barakaldo, Spain.; Department of Neurosciences, University of the Basque Country, UPV/EHU, Leioa, Spain.
Segarra R; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain.; Department of Psychiatry, Cruces University Hospital, Barakaldo, Spain.; Department of Neurosciences, University of the Basque Country, UPV/EHU, Leioa, Spain.
Etxebarria N; Department of Analytical Chemistry, University of the Basque Country UPV/EHU, Leioa, Spain.; PiE-UPV/EHU, Plentzia, ItsasEstazioa, Areatza Pasealekua, 48620, Plentzia, Spain.
Callado LF; Department of Pharmacology, University of the Basque Country, UPV/EHU, Leioa, Spain.; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain.
Urigüen L; Department of Pharmacology, University of the Basque Country, UPV/EHU, Leioa, Spain. .; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain. .; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain. .
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Źródło:
Molecular neurobiology [Mol Neurobiol] 2023 Aug; Vol. 60 (8), pp. 4472-4487. Date of Electronic Publication: 2023 Apr 28.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Culture Techniques*/methods
Cell Differentiation*
Cell Separation*/methods
Neurogenesis*
Neuroglia*/cytology
Neurons*/cytology
Olfactory Mucosa*/cytology
Humans ; Basement Membrane/cytology ; Biomarkers/analysis ; Cell Adhesion ; Cell Proliferation ; Cells, Cultured ; Culture Media/chemistry ; Flow Cytometry ; Immunohistochemistry ; Magnetics ; Neural Stem Cells/cytology ; Organ Specificity
Czasopismo naukowe
Tytuł:
Synthetic peptides activating discoidin domain receptor 2 and collagen-binding integrins cooperate to stimulate osteoblast differentiation of skeletal progenitor cells.
Autorzy:
Ge C; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA.
Li Y; Department of Biologic and Materials Sciences and Prosthodontics, University of Michigan School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA.
Wu F; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA; Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Ma P; Department of Biologic and Materials Sciences and Prosthodontics, University of Michigan School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA.
Franceschi RT; Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, 1011 N. University Avenue, Ann Arbor, MI 48109-1078, USA. Electronic address: .
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Źródło:
Acta biomaterialia [Acta Biomater] 2023 Aug; Vol. 166, pp. 109-118. Date of Electronic Publication: 2023 May 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Stem Cells*/cytology
Osteoblasts*/cytology
Cell Differentiation*/drug effects
Animals ; Mice ; Cell Line ; Collagen/chemistry ; Peptides/chemistry ; Peptides/pharmacology ; Discoidin Domain Receptor 2/chemistry ; Integrins/chemistry ; Phosphorylation ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
p53 governs an AT1 differentiation programme in lung cancer suppression.
Autorzy:
Kaiser AM; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Gatto A; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Hanson KJ; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Zhao RL; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Raj N; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Ozawa MG; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Seoane JA; Cancer Computational Biology Group, Vall d'Hebron Institute of Oncology, Barcelona, Spain.
Bieging-Rolett KT; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Wang M; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Li I; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA.
Trope WL; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Liou DZ; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Shrager JB; Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Plevritis SK; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA.
Newman AM; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA.
Van Rechem C; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Attardi LD; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA. .; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. .
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Źródło:
Nature [Nature] 2023 Jul; Vol. 619 (7971), pp. 851-859. Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Alveolar Epithelial Cells*/cytology
Alveolar Epithelial Cells*/metabolism
Alveolar Epithelial Cells*/pathology
Cell Differentiation*
Lung*/cytology
Lung*/metabolism
Lung*/pathology
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Lung Neoplasms*/prevention & control
Tumor Suppressor Protein p53*/deficiency
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Animals ; Mice ; Mice, Knockout ; Alleles ; Gene Expression Profiling ; Chromatin Assembly and Disassembly ; DNA/metabolism ; Lung Injury/genetics ; Lung Injury/metabolism ; Lung Injury/pathology ; Disease Progression ; Cell Lineage ; Regeneration ; Cell Self Renewal
Czasopismo naukowe
Tytuł:
Function and molecular mechanism of a poplar placenta limited MIXTA gene in regulating differentiation of plant epidermal cells.
Autorzy:
Zhou F; State Key Laboratory of Tree Genetics and Breeding, Co-Innovation Center for Sustainable Forestry in Southern China, Key Laboratory of Tree Genetics and Biotechnology of Educational Department of China, Key Laboratory of Tree Genetics and Silvicultural Sciences of Jiangsu Province, Nanjing Forestry University, Nanjing 210037, China.
Wu H; State Key Laboratory of Tree Genetics and Breeding, Co-Innovation Center for Sustainable Forestry in Southern China, Key Laboratory of Tree Genetics and Biotechnology of Educational Department of China, Key Laboratory of Tree Genetics and Silvicultural Sciences of Jiangsu Province, Nanjing Forestry University, Nanjing 210037, China.
Chen Y; State Key Laboratory of Tree Genetics and Breeding, Co-Innovation Center for Sustainable Forestry in Southern China, Key Laboratory of Tree Genetics and Biotechnology of Educational Department of China, Key Laboratory of Tree Genetics and Silvicultural Sciences of Jiangsu Province, Nanjing Forestry University, Nanjing 210037, China.
Wang M; State Key Laboratory of Tree Genetics and Breeding, Co-Innovation Center for Sustainable Forestry in Southern China, Key Laboratory of Tree Genetics and Biotechnology of Educational Department of China, Key Laboratory of Tree Genetics and Silvicultural Sciences of Jiangsu Province, Nanjing Forestry University, Nanjing 210037, China.
Tuskan GA; Center for Bioenergy Innovation, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
Yin T; State Key Laboratory of Tree Genetics and Breeding, Co-Innovation Center for Sustainable Forestry in Southern China, Key Laboratory of Tree Genetics and Biotechnology of Educational Department of China, Key Laboratory of Tree Genetics and Silvicultural Sciences of Jiangsu Province, Nanjing Forestry University, Nanjing 210037, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Jul 01; Vol. 242 (Pt 2), pp. 124743. Date of Electronic Publication: 2023 May 06.
Typ publikacji:
Journal Article
MeSH Terms:
Plant Epidermis*/cytology
Plant Epidermis*/genetics
Plant Epidermis*/growth & development
Populus*/cytology
Populus*/genetics
Populus*/growth & development
Cell Differentiation*/genetics
Gene Expression Regulation, Plant*
Gene Expression Regulation, Developmental*
Plant Proteins*/genetics
Plant Proteins*/metabolism
Plant Cone*/genetics
Plant Cone*/growth & development
Arabidopsis ; Promoter Regions, Genetic ; Pollination
Czasopismo naukowe

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