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Wyszukujesz frazę ""Cell Differentiation"" wg kryterium: Temat


Tytuł :
Cholera toxin induces food allergy through Th2 cell differentiation which is unaffected by Jagged2.
Autorzy :
Sun S; Key Laboratory of Precision Nutrition and Food Quality, Key Laboratory of Functional Dairy, Ministry of Education, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Jiang S; College of Food Science and Engineering, Yangzhou University, No.88 Daxue South Road, Hanjiang District, Yangzhou, Jiangsu Province, China.
Wang J; Key Laboratory of Precision Nutrition and Food Quality, Key Laboratory of Functional Dairy, Ministry of Education, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Chen C; Key Laboratory of Precision Nutrition and Food Quality, Key Laboratory of Functional Dairy, Ministry of Education, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Han S; Key Laboratory of Precision Nutrition and Food Quality, Key Laboratory of Functional Dairy, Ministry of Education, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Che H; Key Laboratory of Precision Nutrition and Food Quality, Key Laboratory of Functional Dairy, Ministry of Education, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Dec 15; Vol. 263, pp. 118514. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Disease Models, Animal*
Cholera Toxin/*toxicity
Food Hypersensitivity/*etiology
Jagged-2 Protein/*metabolism
Th2 Cells/*immunology
Adjuvants, Immunologic/toxicity ; Animals ; Cytokines/metabolism ; Dendritic Cells/drug effects ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Female ; Food Hypersensitivity/metabolism ; Food Hypersensitivity/pathology ; Jagged-2 Protein/genetics ; Mice ; Mice, Inbred BALB C ; Receptors, Notch/metabolism ; Th2 Cells/drug effects ; Th2 Cells/metabolism
Czasopismo naukowe
Tytuł :
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.
Autorzy :
Khavinson VK; Department of Biogerontology, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia.; Group of Peptide Regulation and Aging, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia.
Linkova NS; Department of Biogerontology, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia. .; Department of Therapy, Geriatrics, and Anti-Aging Medicine, Academy of Postgraduate Education under Federal Research Clinical Center of Federal Medical-Biological Agency of Russia, Moscow, Russia. .
Kvetnoy IM; Department of Biogerontology, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia.
Polyakova VO; Department of Biogerontology, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia.
Drobintseva AO; Department of Biogerontology, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia.
Kvetnaia TV; Department of Biogerontology, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia.
Ivko OM; Department of Biogerontology, St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia.
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Źródło :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2020 Nov; Vol. 170 (1), pp. 118-122. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation/*drug effects
Hematopoietic Stem Cells/*drug effects
Hematopoietic Stem Cells/*physiology
Thymus Hormones/*pharmacology
CD28 Antigens/genetics ; CD28 Antigens/metabolism ; COVID-19/immunology ; COVID-19/pathology ; Cell Differentiation/genetics ; Cells, Cultured ; Fetal Blood/cytology ; Gene Expression Regulation/drug effects ; Hematopoietic Stem Cells/pathology ; Humans ; Hyaluronan Receptors/genetics ; Hyaluronan Receptors/metabolism ; Proto-Oncogene Proteins c-kit/genetics ; Proto-Oncogene Proteins c-kit/metabolism ; SARS-CoV-2/immunology ; T-Lymphocytes/drug effects ; T-Lymphocytes/metabolism ; T-Lymphocytes/physiology ; Thymus Hormones/physiology
Czasopismo naukowe
Tytuł :
In situ differentiation of iridophore crystallotypes underlies zebrafish stripe patterning.
Autorzy :
Gur D; HHMI Janelia Research Campus, Ashburn, VA, USA.; National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.
Bain EJ; Department of Biology, University of Virginia, Charlottesville, VA, USA.; Department of Biology and Department of Cell Biology, University of Virginia, Charlottesville, VA, USA.
Johnson KR; Bioinformatics Section, National Institute of Neurological Disorder and Stroke, NIH, Bethesda, MD, USA.
Aman AJ; Department of Biology, University of Virginia, Charlottesville, VA, USA.; Department of Biology and Department of Cell Biology, University of Virginia, Charlottesville, VA, USA.
Pasoili HA; HHMI Janelia Research Campus, Ashburn, VA, USA.
Flynn JD; National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
Allen MC; Marine Biology Research Division, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, USA.
Deheyn DD; Marine Biology Research Division, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, USA.
Lee JC; National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
Lippincott-Schwartz J; HHMI Janelia Research Campus, Ashburn, VA, USA. .
Parichy DM; Department of Biology, University of Virginia, Charlottesville, VA, USA. .; Department of Biology and Department of Cell Biology, University of Virginia, Charlottesville, VA, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 15; Vol. 11 (1), pp. 6391. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Differentiation/*physiology
Chromatophores/*physiology
Chromatophores/*ultrastructure
Skin/*ultrastructure
Skin Pigmentation/*physiology
Zebrafish/*metabolism
Animals ; Cell Differentiation/genetics ; Cell Proliferation/physiology ; Microphthalmia-Associated Transcription Factor ; Mutagenesis ; Skin/metabolism ; Skin Pigmentation/genetics ; Transcriptome ; X-Ray Diffraction ; Zebrafish/genetics ; Zebrafish Proteins/genetics
Czasopismo naukowe
Tytuł :
Development and characterization of rat duodenal organoids for ADME and toxicology applications.
Autorzy :
Hedrich WD; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Panzica-Kelly JM; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Chen SJ; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Strassle B; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Hasson C; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Lecureux L; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Wang L; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Chen W; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Sherry T; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Gan J; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States.
Davis M; Bristol-Myers Squibb R&D, Pharmaceutical Candidate Optimization, Rt. 206 and Province Line Road, Princeton, NJ, 08648, United States. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2020 Dec 15; Vol. 446, pp. 152614. Date of Electronic Publication: 2020 Oct 24.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents, Non-Steroidal/*toxicity
Cell Differentiation/*drug effects
Duodenum/*drug effects
Intestinal Mucosa/*drug effects
Organoids/*drug effects
Animals ; Anti-Inflammatory Agents, Non-Steroidal/metabolism ; Cell Differentiation/physiology ; Cells, Cultured ; Duodenum/cytology ; Duodenum/metabolism ; Female ; Intestinal Mucosa/cytology ; Intestinal Mucosa/metabolism ; Organoids/metabolism ; Rats ; Rats, Sprague-Dawley ; Stem Cells/drug effects ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells.
Autorzy :
Harsha Krovi S; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Evergrande Center for Immunologic diseases at Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
Zhang J; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Stanford Health Care, Department of Pathology, Stanford University, Stanford, CA, USA.
Michaels-Foster MJ; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Brunetti T; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Loh L; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Scott-Browne J; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, USA.
Gapin L; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. .; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 07; Vol. 11 (1), pp. 6238. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cell Differentiation/*immunology
Immunity, Innate/*immunology
Natural Killer T-Cells/*immunology
Single-Cell Analysis/*methods
T-Lymphocytes/*immunology
Thymus Gland/*immunology
Animals ; Cell Differentiation/genetics ; Cells, Cultured ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/immunology ; DNA-Binding Proteins/metabolism ; Gene Expression Profiling/methods ; Immunity, Innate/genetics ; Mice, Inbred C57BL ; Mice, Knockout ; Mucosal-Associated Invariant T Cells/cytology ; Mucosal-Associated Invariant T Cells/immunology ; Mucosal-Associated Invariant T Cells/metabolism ; Natural Killer T-Cells/cytology ; Natural Killer T-Cells/metabolism ; Sequence Analysis, RNA/methods ; T-Lymphocytes/cytology ; T-Lymphocytes/metabolism ; Thymocytes/cytology ; Thymocytes/immunology ; Thymocytes/metabolism ; Thymus Gland/cytology ; Thymus Gland/metabolism
Czasopismo naukowe
Tytuł :
Effects of the amide alkaloid piperyline on apoptosis, autophagy, and differentiation of pre-osteoblasts.
Autorzy :
Park KR; Department of Oral and Maxillofacial Pathology, School of Dentistry, Kyung HeeUniversity,26, Kyungheedae-ro, Dongdaemun-gu,Seoul02453, South Korea.
Leem HH; National Development Institute of Korean Medicine, Gyeongsan38540, South Korea.
Cho M; National Development Institute of Korean Medicine, Gyeongsan38540, South Korea.
Kang SW; Department of Oral and Maxillofacial Pathology, School of Dentistry, Kyung HeeUniversity,26, Kyungheedae-ro, Dongdaemun-gu,Seoul02453, South Korea. Electronic address: .
Yun HM; Department of Oral and Maxillofacial Pathology, School of Dentistry, Kyung HeeUniversity,26, Kyungheedae-ro, Dongdaemun-gu,Seoul02453, South Korea. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2020 Dec; Vol. 79, pp. 153347. Date of Electronic Publication: 2020 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids/*pharmacology
Cell Differentiation/*drug effects
Osteoblasts/*drug effects
Alkaloids/chemistry ; Animals ; Apoptosis/drug effects ; Apoptosis/physiology ; Autophagy/drug effects ; Autophagy/physiology ; Cell Adhesion/drug effects ; Cell Differentiation/physiology ; Cell Line ; Cell Proliferation/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Focal Adhesion Kinase 1/metabolism ; Matrix Metalloproteinases/metabolism ; Mice ; Osteoblasts/cytology ; Osteoblasts/physiology ; Piper nigrum/chemistry ; Signal Transduction
Czasopismo naukowe
Tytuł :
Irradiation with blue light-emitting diode enhances osteogenic differentiation of stem cells from the apical papilla.
Autorzy :
Yang Y; Southwest Medical University, Luzhou, 646000, China.; Hospital/School of Stomatology, Zunyi Medical University, Zunyi, 563000, China.
Zhu T; Yantai Stomatological Hospital, Yantai, 264000, China.
Wu Y; West China-Guang'an Hospital, Sichuan University, Guang'an, 638550, China.
Shu C; Southwest Medical University, Luzhou, 646000, China.
Chen Q; Southwest Medical University, Luzhou, 646000, China.
Yang J; Southwest Medical University, Luzhou, 646000, China.
Luo X; Southwest Medical University, Luzhou, 646000, China.
Wang Y; Hospital of Stomatology Southwest Medical University, Luzhou, 646000, China. .
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Źródło :
Lasers in medical science [Lasers Med Sci] 2020 Dec; Vol. 35 (9), pp. 1981-1988. Date of Electronic Publication: 2020 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation/*radiation effects
Dental Papilla/*cytology
Osteogenesis/*radiation effects
Stem Cells/*cytology
Stem Cells/*radiation effects
Alkaline Phosphatase/genetics ; Alkaline Phosphatase/metabolism ; Calcium/metabolism ; Cell Differentiation/genetics ; Cell Proliferation/genetics ; Cell Proliferation/radiation effects ; Cells, Cultured ; Dentinogenesis/genetics ; Dentinogenesis/radiation effects ; Extracellular Matrix Proteins/genetics ; Extracellular Matrix Proteins/metabolism ; Gene Expression Regulation/radiation effects ; Humans ; Osteocalcin/genetics ; Osteocalcin/metabolism ; Osteogenesis/genetics ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; Sialoglycoproteins/genetics ; Sialoglycoproteins/metabolism
Czasopismo naukowe
Tytuł :
Single-cell lineage analysis reveals extensive multimodal transcriptional control during directed beta-cell differentiation.
Autorzy :
Weng C; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.; The Biomedical Sciences Training Program (BSTP), School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Xi J; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Li H; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Cui J; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Gu A; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Medical Scientist Training Program (MSTP), School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Lai S; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.; The Biomedical Sciences Training Program (BSTP), School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Leskov K; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Ke L; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Master of Science in Biology Program, Department of Biology, College of Arts and Sciences, Case Western Reserve University, Cleveland, OH, USA.
Jin F; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA. .; Department of Population and Quantitative Health Sciences, Department of Electrical Engineering and Computer Science, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA. .
Li Y; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA. .
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Źródło :
Nature metabolism [Nat Metab] 2020 Dec; Vol. 2 (12), pp. 1443-1458. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation/*physiology
Cell Lineage/*physiology
Gene Expression Regulation, Developmental/*physiology
Insulin-Secreting Cells/*physiology
Cell Differentiation/genetics ; Cell Lineage/genetics ; Diabetes Mellitus/genetics ; Embryonic Stem Cells ; Gene Expression Regulation, Developmental/genetics ; Gene Knockdown Techniques ; Genes, Switch/genetics ; Glucose/pharmacology ; Humans ; Insulin Secretion/drug effects ; Transcription Factor 7-Like 2 Protein/genetics ; Transcription Factor HES-1/biosynthesis ; Transcription Factor HES-1/genetics
Czasopismo naukowe
Tytuł :
Optimal Criteria for G3 (Poorly Differentiated) Stage II Colon Cancer: Prospective Validation in a Randomized Controlled Study (SACURA Trial).
Autorzy :
Ueno H; Departments of Surgery.
Ishiguro M; Departments of Translational Oncology.
Nakatani E; Division of Statistical Analysis of Research Support Center, Shizuoka General Hospital, Shizuoka.; Division of Medical Statistics, Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation at Kobe.
Ishikawa T; Specialized Surgeries, Tokyo Medical and Dental University.
Uetake H; Specialized Surgeries, Tokyo Medical and Dental University.
Matsui S; Department of Biostatistics, Graduate School of Medicine, Nagoya University, Aichi.
Teramukai S; Department of Biostatistics, Kyoto Prefectural University of Medicine, Kyoto.
Murotani K; Biostatistics Center, Kurume University, Graduate School of Medicine.
Ajioka Y; Division of Molecular and Diagnostic Pathology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata.
Shimazaki H; Pathology, National Defense Medical College, Saitama.
Maeda A; Department of Surgery, Ogaki Municipal Hospital, Gifu.
Takuma K; Department of Surgery, Tokyo Metropolitan Tama Medical Center.
Yoshida T; Department of Surgery, Social Insurance Tagawa Hospital, Fukuoka.
Kambara T; Department of Surgery, Chugoku Central Hospital, Hiroshima.
Matsuda K; Department of Surgery, Teikyo University School of Medicine, Tokyo.
Takagane A; Department of Surgery, Hakodate Goryokaku Hospital, Hokkaido, Japan.
Tomita N; Department of Surgery, Division of Lower GI Surgery, Hyogo College of Medicine, Hyogo.
Sugihara K; Tokyo Medical and Dental University.
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Corporate Authors :
SACURA Study Group
Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2020 Dec; Vol. 44 (12), pp. 1685-1698.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Adenocarcinoma/*pathology
Colonic Neoplasms/*pathology
Adenocarcinoma/genetics ; Adenocarcinoma/mortality ; Adenocarcinoma/therapy ; Aged ; Chemotherapy, Adjuvant ; Colectomy ; Colonic Neoplasms/genetics ; Colonic Neoplasms/mortality ; Colonic Neoplasms/therapy ; Disease-Free Survival ; Female ; Humans ; Japan ; Male ; Microsatellite Instability ; Middle Aged ; Neoplasm Grading ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Predictive Value of Tests ; Prospective Studies ; Reproducibility of Results ; Time Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Predictors of early death, serious hemorrhage, and differentiation syndrome in Japanese patients with acute promyelocytic leukemia.
Autorzy :
Minamiguchi H; Division of Hematology, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan. .
Fujita H; Hematology, Saiseikai Yokohama Nanbu Hospital, Yokohama, Japan.
Atsuta Y; The Japanese Data Center for Hematopoietic Cell Transplantation, Nagoya, Japan.; Department of Healthcare Administration, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Asou N; International Medical Center, Saitama Medical University, Hidaka, Japan.
Sakura T; Hematology, Saiseikai Maebashi Hospital, Maebashi, Japan.
Ueda Y; Hematology/Oncology, Kurashiki Central Hospital, Kurashiki, Japan.
Sawa M; Hematology and Oncology, Anjo Kosei Hospital, Anjo, Japan.
Dobashi N; Clinical Oncology and Hematology, The Jikei University School of Medicine, Tokyo, Japan.
Taniguchi Y; Hematology and Rheumatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
Suzuki R; Hematology and Oncology, Tokai University Faculty of Medicine, Isahara, Japan.
Uchino Y; Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan.
Tomita A; Hematology, Fujita Health University School of Medicine, Toyoake, Japan.
Tamaki S; Hematology, Japanese Red Cross Ise Hospital, Ise, Japan.
Hagihara M; Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan.
Fujimaki K; Hematology, Fujisawa City Hospital, Fujisawa, Japan.
Yanada M; Hematology and Cell Therapy, Aichi Cancer Center, Nagoya, Japan.
Maeda Y; Hematology, Oncology and Respiratory Medicine, Okayama University Medical School, Okayama, Japan.
Iwanaga M; Clinical Epidemiology, Nagasaki University School of Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Usui N; Clinical Oncology and Hematology, The Jikei University School of Medicine, Tokyo, Japan.
Kobayashi Y; Hematology, National Cancer Center Hospital, Tokyo, Japan.; Hematology, International University of Health and Welfare, Mita Hospital, Tokyo, Japan.
Ohtake S; Kanazawa University, Kanazawa, Japan.
Kiyoi H; Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Matsumura I; Hematology and Rheumatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.
Miyazaki Y; Hematology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan.
Naoe T; National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
Takeshita A; Transfusion and Cell Therapy, Hamamatsu University School of Medicine, Hamamatsu, Japan.
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Corporate Authors :
Japan Adult Leukemia Study Group
Źródło :
Annals of hematology [Ann Hematol] 2020 Dec; Vol. 99 (12), pp. 2787-2800. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Clinical Trial; Journal Article
MeSH Terms :
Severity of Illness Index*
Cell Differentiation/*physiology
Hemorrhage/*diagnosis
Hemorrhage/*mortality
Leukemia, Promyelocytic, Acute/*diagnosis
Leukemia, Promyelocytic, Acute/*mortality
Adolescent ; Adult ; Aged ; Anticoagulants/pharmacology ; Anticoagulants/therapeutic use ; Cell Differentiation/drug effects ; Female ; Hemorrhage/drug therapy ; Humans ; Japan ; Leukemia, Promyelocytic, Acute/drug therapy ; Male ; Middle Aged ; Mortality/trends ; Predictive Value of Tests ; Prospective Studies ; Remission Induction/methods ; Young Adult
Czasopismo naukowe
Tytuł :
Zinc deficiency induces abnormal development of the myocardium by promoting SENP5 overexpression.
Autorzy :
Zhang X; Department of Neonatology, Tianjin Medical University, Tianjin, P.R. China.
Wang C; Department of Cardiology, Tianjin Fifth Central Hospital, Tianjin, P.R. China.
Zhao D; Department of Neonatology, The Second Hospital of Tianjin Medical University, Tianjin, P.R. China.
Chen X; Department of Obstetrics and Gynecology, Tianjin Fifth Central Hospital, Tianjin, P.R. China.
Zhang C; Department of Pharmacy, Tianjin Binhai New Area Hospital of Traditional Chinese Medicine, Tianjin, P.R. China.
Zheng J; Department of Neonatology, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, P.R. China.
Liu X; Central Laboratory, The Fifth Central Hospital of Tianjin, Tianjin, P.R. China.
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Źródło :
PloS one [PLoS One] 2020 Nov 19; Vol. 15 (11), pp. e0242606. Date of Electronic Publication: 2020 Nov 19 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Gene Expression Regulation*
Gene Expression Regulation, Enzymologic*
Induced Pluripotent Stem Cells/*metabolism
Myocardium/*enzymology
Myocytes, Cardiac/*enzymology
Peptide Hydrolases/*biosynthesis
Zinc/*deficiency
Animals ; Cell Line ; Female ; Humans ; Induced Pluripotent Stem Cells/pathology ; Male ; Mice ; Myocardium/pathology ; Myocytes, Cardiac/pathology ; SUMO-1 Protein/metabolism
Czasopismo naukowe
Tytuł :
Poison Exon Splicing Regulates a Coordinated Network of SR Protein Expression during Differentiation and Tumorigenesis.
Autorzy :
Leclair NK; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA; Graduate Program in Genetics and Development, UConn Health, Farmington, CT, USA.
Brugiolo M; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Urbanski L; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA; Graduate Program in Genetics and Development, UConn Health, Farmington, CT, USA.
Lawson SC; Graduate Program in Genetics and Development, UConn Health, Farmington, CT, USA; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA.
Thakar K; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Yurieva M; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
George J; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA; Institute for Systems Genomics, UConn Health, Farmington, CT, USA.
Hinson JT; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA.
Cheng A; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA; Institute for Systems Genomics, UConn Health, Farmington, CT, USA.
Graveley BR; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA; Institute for Systems Genomics, UConn Health, Farmington, CT, USA.
Anczuków O; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA; Institute for Systems Genomics, UConn Health, Farmington, CT, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Nov 19; Vol. 80 (4), pp. 648-665.e9. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cell Differentiation*
Exons*
RNA Splicing*
Breast Neoplasms/*pathology
Myelodysplastic Syndromes/*pathology
Nerve Tissue Proteins/*metabolism
Serine-Arginine Splicing Factors/*metabolism
Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Female ; Humans ; Myelodysplastic Syndromes/genetics ; Myelodysplastic Syndromes/metabolism ; Nerve Tissue Proteins/genetics ; Protein Isoforms ; Serine-Arginine Splicing Factors/genetics ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Matrine promotes hepatic oval cells differentiation into hepatocytes and alleviates liver injury by suppression of Notch signalling pathway.
Autorzy :
Shi J; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Han G; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Wang J; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Han X; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Zhao M; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Duan X; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Mi L; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Li N; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Yin X; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Shi H; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Li C; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China.
Xu J; Department of Nephrology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China. Electronic address: .
Yin F; Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, ShiJiaZhuang, PR China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 15; Vol. 261, pp. 118354. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*/drug effects
Signal Transduction*
Alkaloids/*pharmacology
Hepatocytes/*pathology
Liver/*injuries
Liver/*pathology
Quinolizines/*pharmacology
Receptors, Notch/*metabolism
Animals ; Apoptosis/drug effects ; Cell Survival/drug effects ; Disease Models, Animal ; Fatty Liver/pathology ; Fatty Liver/physiopathology ; Female ; Hepatocytes/drug effects ; Hepatocytes/metabolism ; Humans ; Kaplan-Meier Estimate ; Liver/drug effects ; Liver/physiopathology ; Liver Function Tests ; Male ; Middle Aged ; Prognosis ; Proportional Hazards Models ; RNA, Small Interfering/metabolism ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Differentiation of Monocytes into Phenotypically Distinct Macrophages After Treatment with Human Cord Blood Stem Cell (CB-SC)-Derived Exosomes.
Autorzy :
Hu W; Center for Discovery and Innovation, Hackensack Meridian Health Center; Department of Chemistry and Chemistry Biology, Stevens Institute of Technology.
Song X; Center for Discovery and Innovation, Hackensack Meridian Health Center.
Yu H; Center for Discovery and Innovation, Hackensack Meridian Health Center.
Sun J; Department of Chemistry and Chemistry Biology, Stevens Institute of Technology.
Zhao Y; Center for Discovery and Innovation, Hackensack Meridian Health Center; .
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Źródło :
Journal of visualized experiments : JoVE [J Vis Exp] 2020 Nov 12 (165). Date of Electronic Publication: 2020 Nov 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms :
Cell Differentiation*
Exosomes/*metabolism
Fetal Blood/*cytology
Macrophages/*cytology
Monocytes/*cytology
Stem Cells/*cytology
Cells, Cultured ; Coculture Techniques ; Dynamic Light Scattering ; Exosomes/ultrastructure ; Humans ; Phenotype ; Reproducibility of Results ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł :
c-Src kinase inhibits osteogenic differentiation via enhancing STAT1 stability.
Autorzy :
Alvandi Z; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Vascular Biology, Boston Children's Hospital, Boston, MA, United States of America.; Department of Surgery, Harvard Medical School, Boston, MA, United States of America.
Opas M; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
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Źródło :
PloS one [PLoS One] 2020 Nov 12; Vol. 15 (11), pp. e0241646. Date of Electronic Publication: 2020 Nov 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Mouse Embryonic Stem Cells/*drug effects
Osteoblasts/*cytology
Protein Kinase Inhibitors/*pharmacology
Pyrimidines/*pharmacology
STAT1 Transcription Factor/*metabolism
Active Transport, Cell Nucleus ; Animals ; Cell Nucleus/metabolism ; Cells, Cultured ; Core Binding Factor Alpha 1 Subunit/metabolism ; Mice ; Mouse Embryonic Stem Cells/cytology ; Mouse Embryonic Stem Cells/metabolism ; Osteoblasts/metabolism ; Protein Stability ; src-Family Kinases/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Mitchell-Riley syndrome iPSCs exhibit reduced pancreatic endoderm differentiation due to a mutation in RFX6 .
Autorzy :
Trott J; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.
Alpagu Y; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551.
Tan EK; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Clinical Sciences Building, 11 Mandalay Road, 308232, Singapore.
Shboul M; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.; Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid 2210, Jordan.
Dawood Y; Department of Medical Biology, Section Clinical Anatomy and Embryology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.; Department of Obstetrics and Gynaecology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Elsy M; Faculty of Biology, Medicine & Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Wollmann H; Institute of Molecular and Cellular Biology, Agency for Science Technology and Research (A*STAR), 61 Biopolis Drive, 138673, Singapore.
Tano V; Lee Kong Chian School of Medicine, Nanyang Technological University, Clinical Sciences Building, 11 Mandalay Road, 308232, Singapore.
Bonnard C; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.
Eng S; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.
Narayanan G; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.
Junnarkar S; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.
Wearne S; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.
Strutt J; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.
Kumar A; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Clinical Sciences Building, 11 Mandalay Road, 308232, Singapore.
Tomaz LB; Lee Kong Chian School of Medicine, Nanyang Technological University, Clinical Sciences Building, 11 Mandalay Road, 308232, Singapore.
Goy PA; Institute of Molecular and Cellular Biology, Agency for Science Technology and Research (A*STAR), 61 Biopolis Drive, 138673, Singapore.
Mzoughi S; Institute of Molecular and Cellular Biology, Agency for Science Technology and Research (A*STAR), 61 Biopolis Drive, 138673, Singapore.
Jennings R; Faculty of Biology, Medicine & Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; Endocrinology Department, Manchester University NHS Foundation Trust, Grafton Street, Manchester M13 9WU, UK.
Hagoort J; Department of Medical Biology, Section Clinical Anatomy and Embryology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Eskin A; Department of Human Genetics, David Geffen School of Medicine at UCLA, 695 Charles E. Young Drive South, Box 708822, Los Angeles, CA 90095-7088, USA.; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Lee H; Department of Human Genetics, David Geffen School of Medicine at UCLA, 695 Charles E. Young Drive South, Box 708822, Los Angeles, CA 90095-7088, USA.; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Nelson SF; Department of Human Genetics, David Geffen School of Medicine at UCLA, 695 Charles E. Young Drive South, Box 708822, Los Angeles, CA 90095-7088, USA.; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.; Department of Pediatrics, UCLA Mattel Children's Hospital, Los Angeles, CA 90095, USA.
Al-Kazaleh F; Department of Obstetrics and Gynecology, University of Jordan, Amman 19241, Jordan.
El-Khateeb M; National Center for Diabetes, Endocrinology and Genetics, Amman 19241, Jordan.
Fathallah R; National Center for Diabetes, Endocrinology and Genetics, Amman 19241, Jordan.
Shah H; Department of Obstetrics and Gynaecology, Queen Charlotte's & Chelsea Hospital, Imperial College London, Du Cane Road, London W12 0HS, UK.
Goeke J; Genome Institute of Singapore, Agency for Science Technology and Research (A*STAR), 60 Biopolis Street, 138672, Singapore.
Langley SR; Lee Kong Chian School of Medicine, Nanyang Technological University, Clinical Sciences Building, 11 Mandalay Road, 308232, Singapore.
Guccione E; Institute of Molecular and Cellular Biology, Agency for Science Technology and Research (A*STAR), 61 Biopolis Drive, 138673, Singapore.
Hanley N; Faculty of Biology, Medicine & Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.; Endocrinology Department, Manchester University NHS Foundation Trust, Grafton Street, Manchester M13 9WU, UK.
De Bakker BS; Department of Medical Biology, Section Clinical Anatomy and Embryology, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Reversade B; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore.; Institute of Molecular and Cellular Biology, Agency for Science Technology and Research (A*STAR), 61 Biopolis Drive, 138673, Singapore.; Department of Paediatrics, National University of Singapore, Yong Loo Lin School of Medicine, 1E Kent Ridge Road, NUHS Tower Block, Level 12, 119228, Singapore.; Koç University School of Medicine, Medical Genetics Department, Istanbul 34450, Turkey.
Dunn NR; Institute of Medical Biology, Agency for Science Technology and Research (A*STAR), 8A Biomedical Grove, #06-06 Immunos, 138648, Singapore .; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551.; Lee Kong Chian School of Medicine, Nanyang Technological University, Clinical Sciences Building, 11 Mandalay Road, 308232, Singapore.
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Źródło :
Development (Cambridge, England) [Development] 2020 Nov 05; Vol. 147 (21). Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*/genetics
Diabetes Mellitus/*genetics
Diabetes Mellitus/*pathology
Endoderm/*embryology
Gallbladder Diseases/*genetics
Gallbladder Diseases/*pathology
Induced Pluripotent Stem Cells/*pathology
Intestinal Atresia/*genetics
Intestinal Atresia/*pathology
Mutation/*genetics
Pancreas/*embryology
Regulatory Factor X Transcription Factors/*genetics
Alleles ; Base Sequence ; Chromatin/metabolism ; Consanguinity ; Diabetes Mellitus/diagnostic imaging ; Embryo, Mammalian/metabolism ; Embryonic Development ; Family ; Female ; Gallbladder Diseases/diagnostic imaging ; Genome, Human ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Intestinal Atresia/diagnostic imaging ; Male ; Pedigree ; Transcription, Genetic ; Transcriptome/genetics ; X-Ray Microtomography
SCR Disease Name :
Mitchell-Riley Syndrome
Czasopismo naukowe
Tytuł :
B3GALT5 knockout alters gycosphingolipid profile and facilitates transition to human naïve pluripotency.
Autorzy :
Lin RJ; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, Taiwan.
Kuo MW; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, Taiwan.
Yang BC; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, Taiwan.
Tsai HH; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, Taiwan.
Chen K; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, Taiwan.
Huang JR; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, Taiwan.
Lee YS; Department of Biotechnology, Ming-Chuan University, 333 Taoyuan, Taiwan.
Yu AL; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, Taiwan.; Genomics Research Center, Academia Sinica, 115 Taipei, Taiwan.; Division of Hematology and Oncology, Department of Pediatrics, University of California, San Diego, CA 92123.
Yu J; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, 333 Taoyuan, Taiwan; .; Institute of Cellular and Organismic Biology, Academia Sinica, 115 Taipei, Taiwan.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Nov 03; Vol. 117 (44), pp. 27435-27444. Date of Electronic Publication: 2020 Oct 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Galactosyltransferases/*metabolism
Glycosphingolipids/*metabolism
Pluripotent Stem Cells/*metabolism
Stage-Specific Embryonic Antigens/*metabolism
CRISPR-Cas Systems/genetics ; Cell Line ; Embryonic Stem Cells ; Galactosyltransferases/genetics ; Gene Knockdown Techniques ; Humans
Czasopismo naukowe
Tytuł :
Negative prognostic impact of PD-L1 expression in tumor cells of undifferentiated (anaplastic) carcinoma with osteoclast-like giant cells of the pancreas: study of 13 cases comparing ductal pancreatic carcinoma and review of the literature.
Autorzy :
Hrudka J; Department of Pathology, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic. .
Lawrie K; Department of General Surgery, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.
Waldauf P; Department of Anesthesiology and Intensive Care, 3rd Faculty of Medicine, Charles University and Kralovske Vinohrady University Hospital, Prague, Czech Republic.
Ciprová V; Institute of Pathology, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Moravcová J; Department of Pathology, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.; Clinical and Transplant Pathology Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Matěj R; Department of Pathology, 3rd Faculty of Medicine, Charles University, University Hospital Kralovske Vinohrady, Prague, Czech Republic.; Institute of Pathology, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.; Department of Pathology and Molecular Medicine, 3rd Faculty of Medicine, Charles University, Thomayer Hospital, Prague, Czech Republic.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2020 Nov; Vol. 477 (5), pp. 687-696. Date of Electronic Publication: 2020 May 18.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
Cell Differentiation*
B7-H1 Antigen/*analysis
Biomarkers, Tumor/*analysis
Carcinoma, Pancreatic Ductal/*immunology
Giant Cells/*immunology
Osteoclasts/*immunology
Pancreatic Neoplasms/*immunology
Adult ; Aged ; Carcinoma, Pancreatic Ductal/mortality ; Carcinoma, Pancreatic Ductal/pathology ; Carcinoma, Pancreatic Ductal/therapy ; Female ; Giant Cells/pathology ; Humans ; Immunohistochemistry ; Lymphocytes, Tumor-Infiltrating/immunology ; Male ; Middle Aged ; Osteoclasts/pathology ; Pancreatic Neoplasms/mortality ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/therapy ; Predictive Value of Tests ; Prognosis ; Retrospective Studies ; Risk Factors
Czasopismo naukowe
Tytuł :
Three-dimensional induced pluripotent stem-cell models of human brain angiogenesis.
Autorzy :
Linville RM; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States of America; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States of America.
Arevalo D; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States of America; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States of America.
Maressa JC; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States of America; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, United States of America.
Zhao N; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States of America.
Searson PC; Institute for Nanobiotechnology, Johns Hopkins University, Baltimore, MD, United States of America; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States of America; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD, United States of America. Electronic address: .
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Źródło :
Microvascular research [Microvasc Res] 2020 Nov; Vol. 132, pp. 104042. Date of Electronic Publication: 2020 Jul 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Differentiation*/drug effects
Neovascularization, Physiologic*/drug effects
Blood-Brain Barrier/*physiology
Brain/*blood supply
Endothelial Cells/*physiology
Induced Pluripotent Stem Cells/*physiology
Angiogenesis Inducing Agents/pharmacology ; Blood-Brain Barrier/drug effects ; Cell Culture Techniques ; Cells, Cultured ; Endothelial Cells/drug effects ; Extracellular Matrix/physiology ; Humans ; Induced Pluripotent Stem Cells/drug effects ; Models, Cardiovascular ; Neovascularization, Pathologic ; Oxidative Stress ; Phenotype ; Wnt Signaling Pathway
Czasopismo naukowe
Tytuł :
[Multiple differentiation potential of human periodontal ligament stem cells expressing stromal cell antigen 1 (STRO-1) sorted by MACS].
Autorzy :
Zhao Y; State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Department of General Dentistry & Emergency, School of Stomatology, Air Force Medical University, Xi'an 710032, China.
Tu T; State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Department of General Dentistry & Emergency, School of Stomatology, Air Force Medical University, Xi'an 710032, China.
Feng F; State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Department of General Dentistry & Emergency, School of Stomatology, Air Force Medical University, Xi'an 710032, China.
Zhang M; State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi International Joint Research Center for Oral Diseases, Department of General Dentistry & Emergency, School of Stomatology, Air Force Medical University, Xi'an 710032, China. *Corresponding author, E-mail:.
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Źródło :
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi] 2020 Nov; Vol. 36 (11), pp. 971-976.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Differentiation*
Periodontal Ligament*/cytology
Stem Cells*
Antigens, Surface/metabolism ; Cell Separation ; Cells, Cultured ; Humans ; Osteogenesis ; Stromal Cells
Czasopismo naukowe

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