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Wyszukujesz frazę ""Cell Differentiation"" wg kryterium: Temat


Tytuł:
Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia.
Autorzy:
Yi C; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
He J; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Huang D; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhao Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Zhang C; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Ye X; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Huang Y; NMPA Key Laboratory of Rapid Drug Inspection Technology, Guangdong Institute for Drug Control, 766 Shenzhou Road, Guangzhou, 510663, China.
Nussinov R; Computational Structural Biology Section, Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, 21702, USA.; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, 69978, Israel.
Zheng J; Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
Liu M; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. .
Lu W; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. .
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Źródło:
Cell death & disease [Cell Death Dis] 2022 Nov 27; Vol. 13 (11), pp. 1004. Date of Electronic Publication: 2022 Nov 27.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*/genetics
Cell Differentiation*/physiology
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Leukemia, Myeloid, Acute*/metabolism
Leukemia, Myeloid, Acute*/pathology
Receptors, G-Protein-Coupled*/genetics
Receptors, G-Protein-Coupled*/metabolism
Animals ; Humans ; Mice ; Carrier Proteins/metabolism ; Mammals ; Signal Transduction/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
The mitochondrial micropeptide Stmp1 promotes retinal cell differentiation.
Autorzy:
Zheng X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Guo Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Zhang R; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Chen H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Liu S; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Qiu S; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.
Xiang M; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China; Guangdong Provincial Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Dec 25; Vol. 636 (Pt 2), pp. 79-86. Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*
Mitochondria*/metabolism
Retina*/cytology
Mitochondrial Proteins*/physiology
Intracellular Signaling Peptides and Proteins*/physiology
Animals ; Mice ; Ependymoglial Cells/cytology ; Neurons/cytology ; RNA, Untranslated/genetics
Czasopismo naukowe
Tytuł:
Genetic control of the pluripotency epigenome determines differentiation bias in mouse embryonic stem cells.
Autorzy:
Byers C; The Jackson Laboratory, Bar Harbor, ME, USA.; Graduate School of Biomedical Sciences, Tufts University, Boston, MA, USA.
Spruce C; The Jackson Laboratory, Bar Harbor, ME, USA.
Fortin HJ; The Jackson Laboratory, Bar Harbor, ME, USA.; Graduate School of Biomedical Sciences, Tufts University, Boston, MA, USA.
Hartig EI; The Jackson Laboratory, Bar Harbor, ME, USA.; Graduate School of Biomedical Sciences, Tufts University, Boston, MA, USA.
Czechanski A; The Jackson Laboratory, Bar Harbor, ME, USA.
Munger SC; The Jackson Laboratory, Bar Harbor, ME, USA.; Graduate School of Biomedical Sciences, Tufts University, Boston, MA, USA.
Reinholdt LG; The Jackson Laboratory, Bar Harbor, ME, USA.
Skelly DA; The Jackson Laboratory, Bar Harbor, ME, USA.
Baker CL; The Jackson Laboratory, Bar Harbor, ME, USA.; Graduate School of Biomedical Sciences, Tufts University, Boston, MA, USA.
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Źródło:
The EMBO journal [EMBO J] 2022 Dec 17; Vol. 41 (2), pp. e109445. Date of Electronic Publication: 2021 Dec 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*
Epigenome*
Mouse Embryonic Stem Cells/*metabolism
Animals ; Cell Lineage ; Chromatin Assembly and Disassembly ; Gene Expression Regulation, Developmental ; Gene Regulatory Networks ; Mice ; Mice, Inbred DBA ; Mouse Embryonic Stem Cells/cytology ; Regulatory Sequences, Nucleic Acid
Czasopismo naukowe
Tytuł:
Optimization of 3D islet-like cluster derived from human pluripotent stem cells: An efficient in vitro differentiation protocol.
Autorzy:
Ghorbani-Dalini S; Department of Research and Development, CBSAlife Ltd., Richardson Center of Food Technology and Research, Winnipeg, Manitoba, Canada; Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Azarpira N; Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: .
Sangtarash MH; Department of Biology, University of Sistan and Baluchestan, Zahedan, Iran.
Urbach V; Insitut National de la Santé Et de la Recherche Médicale, U1151 Paris, France.
Yaghobi R; Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Soleimanpour-Lichaei HR; Department of Stem Cells and Regenerative Medicine, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
Sarshar M; Research Laboratories, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
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Źródło:
Gene [Gene] 2022 Dec 15; Vol. 845, pp. 146855. Date of Electronic Publication: 2022 Sep 01.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Culture Techniques, Three Dimensional*/methods
Cell Differentiation*
Induced Pluripotent Stem Cells*/metabolism
Pluripotent Stem Cells*/metabolism
Animals ; Glucose/metabolism ; Humans ; Insulin/metabolism ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/metabolism ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of the ATG4-LC3 pathway suppressed osteoclast maturation.
Autorzy:
Hiura F; Laboratory of Molecular and Cellular Biochemistry, Division of Oral Biological Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Kawabata Y; Department of Cell Biology, Aging Science, and Pharmacology, Division of Oral Biological Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Aoki T; Laboratory of Molecular and Cellular Biochemistry, Division of Oral Biological Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Mizokami A; Oral Health/Brain Health/Total Health Research Center, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Jimi E; Laboratory of Molecular and Cellular Biochemistry, Division of Oral Biological Sciences, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan; Oral Health/Brain Health/Total Health Research Center, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Dec 03; Vol. 632, pp. 40-47. Date of Electronic Publication: 2022 Sep 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Osteoclasts*/metabolism
Cell Differentiation*/genetics
Animals ; Male ; Mice ; Actins/metabolism ; Alveolar Bone Loss ; Ligands ; Macrophage Colony-Stimulating Factor/pharmacology ; Macrophage Colony-Stimulating Factor/metabolism ; Matrix Metalloproteinase 9/metabolism ; Microtubule-Associated Proteins/antagonists & inhibitors ; Microtubule-Associated Proteins/metabolism ; Phosphatidylethanolamines/metabolism ; Receptor Activator of Nuclear Factor-kappa B/metabolism ; Silk ; Bone Resorption/genetics ; Bone Resorption/metabolism ; Autophagy-Related Proteins/antagonists & inhibitors ; Autophagy-Related Proteins/metabolism ; Cysteine Endopeptidases/metabolism
Czasopismo naukowe
Tytuł:
BCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation.
Autorzy:
Wischhof L; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Lee HM; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Tutas J; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Overkott C; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Tedt E; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Stork M; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Peitz M; Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty and University Hospital Bonn, Bonn, Germany.; Cell Programming Core Facility, University of Bonn Medical Faculty, Bonn, Germany.
Brüstle O; Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty and University Hospital Bonn, Bonn, Germany.
Ulas T; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, Bonn, Germany.
Händler K; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, Bonn, Germany.
Schultze JL; PRECISE Platform for Single Cell Genomics and Epigenomics, German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, Bonn, Germany.; Department for Genomics and Immunoregulation, LIMES Institute, University of Bonn, Bonn, Germany.
Ehninger D; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Nicotera P; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Salomoni P; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Bano D; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
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Źródło:
The EMBO journal [EMBO J] 2022 Dec 01; Vol. 41 (23), pp. e110595. Date of Electronic Publication: 2022 Oct 28.
Typ publikacji:
Journal Article
MeSH Terms:
Microfilament Proteins*/metabolism
Neural Stem Cells*/cytology
Cell Differentiation*
Animals ; Mice ; Adenosine Triphosphatases/metabolism ; Chromatin Assembly and Disassembly ; Energy Metabolism ; Mitochondria/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Growth Differentiation Factor 7 promotes multiple-lineage differentiation in tenogenic cultures of mesenchymal stem cells.
Autorzy:
Kumlin M; Trauma and Reparative Medicine, Karolinska University Hospital, Stockholm, Sweden; The Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden. Electronic address: .
Lindberg K; The Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Haldosen LA; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
Felländer-Tsai L; Trauma and Reparative Medicine, Karolinska University Hospital, Stockholm, Sweden; The Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Li Y; Trauma and Reparative Medicine, Karolinska University Hospital, Stockholm, Sweden; The Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
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Źródło:
Injury [Injury] 2022 Dec; Vol. 53 (12), pp. 4165-4168. Date of Electronic Publication: 2022 Sep 17.
Typ publikacji:
Letter
MeSH Terms:
Bone Morphogenetic Proteins*/physiology
Cell Differentiation*
Mesenchymal Stem Cells*
Collagen/metabolism ; Animals ; Mice ; Cell Line ; Tendons ; Regeneration
Opinia redakcyjna
Tytuł:
IL-3 regulates the differentiation of pathogenic Th17 cells.
Autorzy:
Rani L; Bone and Cartilage Research Laboratory, National Centre for Cell Science, Pune, 411007, India.
Kumar A; Bone and Cartilage Research Laboratory, National Centre for Cell Science, Pune, 411007, India.
Karhade J; Bone and Cartilage Research Laboratory, National Centre for Cell Science, Pune, 411007, India.
Pandey G; Bone and Cartilage Research Laboratory, National Centre for Cell Science, Pune, 411007, India.
Guha A; Bone and Cartilage Research Laboratory, National Centre for Cell Science, Pune, 411007, India.
Mishra GC; Bone and Cartilage Research Laboratory, National Centre for Cell Science, Pune, 411007, India.
Wani MR; Bone and Cartilage Research Laboratory, National Centre for Cell Science, Pune, 411007, India.
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Źródło:
European journal of immunology [Eur J Immunol] 2022 Nov; Vol. 52 (11), pp. 1842-1858. Date of Electronic Publication: 2022 Sep 26.
Typ publikacji:
Journal Article
MeSH Terms:
Arthritis, Rheumatoid*
Cell Differentiation*
Interleukin-3*/metabolism
Th17 Cells*/cytology
Animals ; Humans ; Mice ; Interleukin-17/metabolism ; Interleukin-2/metabolism ; T-Lymphocytes, Regulatory/cytology
Czasopismo naukowe
Tytuł:
RNA Sequencing of Intestinal Enterocytes Pre- and Post-Roux-en-Y Gastric Bypass Reveals Alteration in Gene Expression Related to Enterocyte Differentiation, Restitution, and Obesity with Regulation by Schlafen 12.
Autorzy:
Vomhof-DeKrey EE; Department of Surgery, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.; Department of Biomedical Sciences, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Singhal S; Department of Pathology, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Singhal SK; Department of Pathology, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Stover AD; Department of Biomedical Sciences, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Rajpathy O; Department of Biomedical Sciences, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Preszler E; Department of Biomedical Sciences, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
Garcia L; Sanford Health Clinic, Sioux Falls, ND 57117, USA.
Basson MD; Department of Surgery, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.; Department of Biomedical Sciences, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.; Department of Pathology, School of Medicine and the Health Sciences, University of North Dakota, Grand Forks, ND 58202, USA.
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Źródło:
Cells [Cells] 2022 Oct 18; Vol. 11 (20). Date of Electronic Publication: 2022 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Enterocytes*/cytology
Enterocytes*/metabolism
Gastric Bypass*
Obesity*/genetics
Obesity*/surgery
Obesity*/metabolism
Intracellular Signaling Peptides and Proteins*/genetics
Cell Differentiation*/genetics
Gene Expression Regulation*
Humans ; Cytidine Diphosphate Diglycerides/metabolism ; F-Box-WD Repeat-Containing Protein 7/metabolism ; Gene Expression ; Intestines ; Membrane Transport Proteins/metabolism ; Sequence Analysis, RNA ; Vesicular Transport Proteins/metabolism
Czasopismo naukowe
Tytuł:
A RORγt cell instructs gut microbiota-specific T reg cell differentiation.
Autorzy:
Kedmi R; Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.
Najar TA; Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.
Mesa KR; Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.
Grayson A; Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.; Howard Hughes Medical Institute, New York, NY, USA.
Kroehling L; Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.
Hao Y; Center for Genomics and Systems Biology, New York University, New York, NY, USA.; New York Genome Center, New York, NY, USA.
Hao S; Technology Innovation Lab, New York Genome Center, New York, NY, USA.
Pokrovskii M; Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.; Calico Life Sciences, LLC, South San Francisco, CA, USA.
Xu M; Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.; National Institute for Biological Sciences, Beijing, China.
Talbot J; Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA.; Fred Hutchinson Cancer Center, Seattle, WA, USA.
Wang J; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.
Germino J; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.
Lareau CA; Department of Pathology, Stanford University, Stanford, CA, USA.; Parker Institute for Cancer Immunotherapy, Stanford University, Stanford, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.
Satpathy AT; Department of Pathology, Stanford University, Stanford, CA, USA.; Parker Institute for Cancer Immunotherapy, Stanford University, Stanford, CA, USA.; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.
Anderson MS; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.
Laufer TM; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Medicine, C. Michael Crescenz Veterans Administration Medical Center, Philadelphia, PA, USA.
Aifantis I; Department of Pathology, New York University School of Medicine, New York, NY, USA.
Bartleson JM; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Federation Bio, South San Francisco, CA, USA.
Allen PM; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Paidassi H; CIRI, Centre International de Recherche en Infectiologie, Université de Lyon, INSERM U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France.
Gardner JM; Diabetes Center, University of California, San Francisco, San Francisco, CA, USA.; Department of Surgery, University of California, San Francisco, San Francisco, CA, USA.
Stoeckius M; Technology Innovation Lab, New York Genome Center, New York, NY, USA.; 10X Genomics, Stockholm, Sweden.
Littman DR; Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY, USA. .; Howard Hughes Medical Institute, New York, NY, USA. .
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Źródło:
Nature [Nature] 2022 Oct; Vol. 610 (7933), pp. 737-743. Date of Electronic Publication: 2022 Sep 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*
Gastrointestinal Microbiome*/immunology
Nuclear Receptor Subfamily 1, Group F, Member 3*/metabolism
T-Lymphocytes, Regulatory*/cytology
T-Lymphocytes, Regulatory*/immunology
Dendritic Cells/immunology ; Homeostasis ; Immunity, Innate ; Integrin alphaV/metabolism ; Receptors, CCR7/metabolism ; Th17 Cells/immunology ; Transforming Growth Factor beta/metabolism ; Antigen Presentation/immunology ; Antigen-Presenting Cells/cytology ; Antigen-Presenting Cells/immunology
Czasopismo naukowe
Tytuł:
Interleukin-11 (IL11) inhibits myogenic differentiation of C2C12 cells through activation of extracellular signal-regulated kinase (ERK).
Autorzy:
Drinkwater K; Arizona College of Osteopathic Medicine, Midwestern University, 19555 N. 59(th) Ave, Glendale, AZ 85308, USA.
Anderson B; Arizona College of Osteopathic Medicine, Midwestern University, 19555 N. 59(th) Ave, Glendale, AZ 85308, USA.
Seangmany N; Arizona College of Osteopathic Medicine, Midwestern University, 19555 N. 59(th) Ave, Glendale, AZ 85308, USA.
Hampel D; Arizona College of Osteopathic Medicine, Midwestern University, 19555 N. 59(th) Ave, Glendale, AZ 85308, USA.
Mody A; Department of Biochemistry and Molecular Genetics, College of Graduate Studies, Midwestern University, 19555 N. 59(th) Ave, Glendale, AZ 85308, USA.
Shim M; Department of Biochemistry and Molecular Genetics, College of Graduate Studies, Midwestern University, 19555 N. 59(th) Ave, Glendale, AZ 85308, USA. Electronic address: .
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Źródło:
Cellular signalling [Cell Signal] 2023 Jan; Vol. 101, pp. 110509. Date of Electronic Publication: 2022 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*
Interleukin-11*/pharmacology
Myoblasts*/drug effects
Myoblasts*/physiology
Animals ; Mice ; Bromodeoxyuridine ; Cachexia ; Extracellular Signal-Regulated MAP Kinases ; Muscle Development ; Myogenin/genetics ; Myosin Heavy Chains/genetics ; Myosin Heavy Chains/metabolism ; Neoplasms
Czasopismo naukowe
Tytuł:
A bifurcation concept for B-lymphoid/plasmacytoid dendritic cells with largely fluctuating transcriptome dynamics.
Autorzy:
Nagaharu K; Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Kojima Y; Division of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Hirose H; Division of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Minoura K; Division of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Hinohara K; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan; Institute for Advanced Research, Nagoya University, Nagoya, Japan.
Minami H; Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Kageyama Y; Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Sugimoto Y; Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Masuya M; Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Nii S; Shiroko Women's Hospital, Suzuka 510-0235, Japan.
Seki M; Department of Computational Biology and Medical Sciences, The University of Tokyo, Kashiwa 277-8561, Japan.
Suzuki Y; Department of Computational Biology and Medical Sciences, The University of Tokyo, Kashiwa 277-8561, Japan.
Tawara I; Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Shimamura T; Division of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan; Institute for Advanced Research, Nagoya University, Nagoya, Japan.
Katayama N; Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
Nishikawa H; Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan; Institute for Advanced Research, Nagoya University, Nagoya, Japan; Division of Cancer Immunology, Research Institute, National Cancer Center, Tokyo 104-0045, Japan; Division of Cancer Immunology, Exploratory Oncology Research and Clinical Trial Center (EPOC), National Cancer Center, Chiba 277-8577, Japan. Electronic address: .
Ohishi K; Department of Transfusion Medicine and Cell Therapy, Mie University Hospital, Tsu 514-8507, Japan. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2022 Aug 30; Vol. 40 (9), pp. 111260.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*/genetics
Dendritic Cells*/metabolism
Lymphocyte Function-Associated Antigen-1*/genetics
Lymphocyte Function-Associated Antigen-1*/metabolism
Hematopoiesis ; Humans ; Transcriptome/genetics
Czasopismo naukowe
Tytuł:
Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential.
Autorzy:
Zhang M; Shenzhen Research Institute of Nanjing University, Shenzhen, China; MOE Key Laboratory of Model Animals for Disease Study and State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center of Medical School, Nanjing University, Nanjing, China.
Liu Y; Shenzhen Research Institute of Nanjing University, Shenzhen, China; MOE Key Laboratory of Model Animals for Disease Study and State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center of Medical School, Nanjing University, Nanjing, China.
Shi L; MOE Key Laboratory of Model Animals for Disease Study and State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center of Medical School, Nanjing University, Nanjing, China.
Fang L; Jiangsu Key Laboratory of Molecular Medicine of Medical School, Nanjing University, Nanjing, China.
Xu L; MOE Key Laboratory of Model Animals for Disease Study and State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center of Medical School, Nanjing University, Nanjing, China.
Cao Y; Shenzhen Research Institute of Nanjing University, Shenzhen, China; MOE Key Laboratory of Model Animals for Disease Study and State Key Laboratory of Pharmaceutical Biotechnology, Model Animal Research Center of Medical School, Nanjing University, Nanjing, China. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Jul; Vol. 298 (7), pp. 102106. Date of Electronic Publication: 2022 Jun 04.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogenesis*
Cell Differentiation*
Histone-Lysine N-Methyltransferase*/genetics
Histone-Lysine N-Methyltransferase*/metabolism
Neural Stem Cells*/cytology
Pluripotent Stem Cells*/cytology
Cell Cycle ; Embryonic Development ; Flavonoids
Czasopismo naukowe
Tytuł:
Rho kinase inhibitor induced human dental pulp stem cells to differentiate into neurons.
Autorzy:
Srikawnawan W; Department of Anatomy, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Songsaad A; Department of Anatomy, Faculty of Dentistry, Mahidol University, Bangkok 10400, Thailand.
Gonmanee T; Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan 10540, Thailand.
Thonabulsombat C; Department of Anatomy, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
Phruksaniyom C; Department of Pharmacology, Faculty of Dentistry, Mahidol University 10400, Bangkok, Thailand.
White KL; Department of Animal, Dairy, and Veterinary Sciences, College of Agriculture and Applied Sciences, Utah State University, Logan, UT, USA.
Ruangsawasdi N; Department of Pharmacology, Faculty of Dentistry, Mahidol University 10400, Bangkok, Thailand. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2022 Jul 01; Vol. 300, pp. 120566. Date of Electronic Publication: 2022 Apr 22.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*
Neurons*/cytology
rho-Associated Kinases*/antagonists & inhibitors
Calcium/pharmacology ; Cells, Cultured ; Dental Pulp/cytology ; Humans ; Stem Cells/cytology ; Tubulin
Czasopismo naukowe
Tytuł:
De novo annotation of lncRNA HOTAIR transcripts by long-read RNA capture-seq reveals a differentiation-driven isoform switch.
Autorzy:
Potolitsyna E; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112, 0317, Oslo, Blindern, Norway.
Hazell Pickering S; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112, 0317, Oslo, Blindern, Norway.; Department of Immunology and Transfusion Medicine, Oslo University Hospital, 0424, Oslo, Norway.
Tooming-Klunderud A; Centre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Oslo, Norway.
Collas P; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112, 0317, Oslo, Blindern, Norway. .; Department of Immunology and Transfusion Medicine, Oslo University Hospital, 0424, Oslo, Norway. .
Briand N; Department of Molecular Medicine, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PO Box 1112, 0317, Oslo, Blindern, Norway. .; Department of Immunology and Transfusion Medicine, Oslo University Hospital, 0424, Oslo, Norway. .
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Źródło:
BMC genomics [BMC Genomics] 2022 Sep 17; Vol. 23 (1), pp. 658. Date of Electronic Publication: 2022 Sep 17.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*/genetics
Protein Isoforms*/genetics
Protein Isoforms*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Biomarkers ; Histone Demethylases ; Humans
Czasopismo naukowe
Tytuł:
Differentiation Capacity of Bone Marrow-Derived Rat Mesenchymal Stem Cells from DsRed and Cre Transgenic Cre/ loxP Models.
Autorzy:
Tseng HC; Department of Medical Imaging, Taipei Tzu Chi General Hospital, Buddhist Tzu-Chi Medical Foundation, New Taipei City 23142, Taiwan.; Department of Research, Taipei Tzu Chi General Hospital, Buddhist Tzu-Chi Medical Foundation, New Taipei City 23142, Taiwan.
Wu MR; Department of Research, Taipei Tzu Chi General Hospital, Buddhist Tzu-Chi Medical Foundation, New Taipei City 23142, Taiwan.
Lee CH; Department of Medical Imaging, Taipei Tzu Chi General Hospital, Buddhist Tzu-Chi Medical Foundation, New Taipei City 23142, Taiwan.; Department of Research, Taipei Tzu Chi General Hospital, Buddhist Tzu-Chi Medical Foundation, New Taipei City 23142, Taiwan.
Hsiao JK; Department of Medical Imaging, Taipei Tzu Chi General Hospital, Buddhist Tzu-Chi Medical Foundation, New Taipei City 23142, Taiwan.; School of Medicine, Tzu Chi University, Hualien 97004, Taiwan.
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Źródło:
Cells [Cells] 2022 Sep 05; Vol. 11 (17). Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*
Mesenchymal Stem Cells*/metabolism
Animals ; Bone Marrow Cells/metabolism ; Integrases ; Luminescent Proteins ; Mammals ; Rats ; Rats, Transgenic
Czasopismo naukowe
Tytuł:
Failure of human rhombic lip differentiation underlies medulloblastoma formation.
Autorzy:
Hendrikse LD; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Haldipur P; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Saulnier O; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Millman J; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Sjoboen AH; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Erickson AW; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Ong W; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Gordon V; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.
Coudière-Morrison L; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.
Mercier AL; PSL Research University, Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Institut Curie, Orsay, France.
Shokouhian M; Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Suárez RA; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Ly M; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Borlase S; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.
Scott DS; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Vladoiu MC; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Farooq H; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Sirbu O; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Nakashima T; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.
Nambu S; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.
Funakoshi Y; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.
Bahcheli A; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Diaz-Mejia JJ; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Golser J; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Bach K; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Phuong-Bao T; Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Skowron P; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Wang EY; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Kumar SA; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Balin P; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Visvanathan A; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Lee JJY; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Ayoub R; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
Chen X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Chen X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Mungall KL; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Luu B; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Bérubé P; McGill University Genome Centre, McGill University, Montreal, Quebec, Canada.
Wang YC; McGill University Genome Centre, McGill University, Montreal, Quebec, Canada.
Pfister SM; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, Immunology and Pulmonology, University Hospital Heidelberg, Heidelberg, Germany.
Kim SK; Department of Neurosurgery, Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, South Korea.
Delattre O; SIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.; INSERM U830, Institut Curie, Paris, France.
Bourdeaut F; SIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.; INSERM U830, Institut Curie, Paris, France.
Doz F; SIREDO Oncology Center (Pediatric, Adolescent and Young Adults Oncology), Institut Curie, Paris, France.; Université Paris Cité, Paris, France.
Masliah-Planchon J; Unit of Somatic Genetics, Institut Curie, Paris, France.
Grajkowska WA; Department of Pathology, The Children's Memorial Health Institute, Warsaw, Poland.
Loukides J; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Dirks P; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada.
Fèvre-Montange M; INSERM U1028, CNRS UMR5292, Centre de Recherche en Neurosciences, Université de Lyon, Lyon, France.; Centre de Pathologie EST, Groupement Hospitalier EST, Université de Lyon, Bron, France.
Jouvet A; Centre de Pathologie EST, Groupement Hospitalier EST, Université de Lyon, Bron, France.
French PJ; Department of Neurology, Erasmus University Medical Center, Rotterdam, Netherlands.
Kros JM; Department of Pathology, Erasmus University Medical Center, Rotterdam, Netherlands.
Zitterbart K; Department of Pediatric Oncology, Masaryk University School of Medicine, Brno, Czech Republic.
Bailey SD; Department of Surgery, Division of Thoracic and Upper Gastrointestinal Surgery, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.; Cancer Research Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Eberhart CG; Departments of Pathology, Ophthalmology and Oncology, John Hopkins University School of Medicine, Baltimore, MD, USA.
Rao AAN; Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, USA.
Giannini C; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Olson JM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Garami M; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Hauser P; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary.
Phillips JJ; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
Ra YS; Department of Neurosurgery, University of Ulsan, Asan Medical Center, Seoul, South Korea.
de Torres C; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
Mora J; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
Li KKW; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Ng HK; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong.
Poon WS; Department of Surgery, The Chinese University of Hong Kong, Shatin, Hong Kong.
Pollack IF; Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
López-Aguilar E; Division of Pediatric Hematology/Oncology, Hospital Pediatría Centro Médico Nacional century XXI, Mexico City, Mexico.
Gillespie GY; Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Van Meter TE; Pediatrics, Virginia Commonwealthy University, School of Medicine, Richmond, VA, USA.
Shofuda T; Division of Stem Cell Research, Institute for Clinical Research, Osaka National Hospital, Osaka, Japan.
Vibhakar R; Department of Pediatrics, University of Colorado Denver, Aurora, CO, USA.
Thompson RC; Department of Neurological Surgery, Vanderbilt Medical Center, Nashville, TN, USA.
Cooper MK; Department of Neurology, Vanderbilt Medical Center, Nashville, TN, USA.
Rubin JB; Departments of Neuroscience, Washington University School of Medicine in St Louis, St Louis, MO, USA.
Kumabe T; Department of Neurosurgery, Kitasato University School of Medicine, Sagamihara, Japan.
Jung S; Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Hwasun-gun, South Korea.
Lach B; Department of Pathology and Molecular Medicine, Division of Anatomical Pathology, McMaster University, Hamilton, Ontario, Canada.; Department of Pathology and Laboratory Medicine, Hamilton General Hospital, Hamilton, Ontario, Canada.
Iolascon A; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy.
Ferrucci V; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy.
de Antonellis P; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy.
Zollo M; Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples Federico II, Naples, Italy.; CEINGE Biotecnologie Avanzate, Naples, Italy.
Cinalli G; Department of Pediatric Neurosurgery, Santobono-Pausilipon Children's Hospital, Naples, Italy.
Robinson S; Division of Pediatric Neurosurgery, Case Western Reserve, Cleveland, OH, USA.
Stearns DS; Department of Pediatrics-Hematology and Oncology, Case Western Reserve, Cleveland, OH, USA.
Van Meir EG; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.
Porrati P; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Finocchiaro G; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Massimino M; Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.
Carlotti CG; Department of Surgery and Anatomy, Faculty of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.
Faria CC; Division of Neurosurgery, Centro Hospitalar Lisboa Norte (CHULN), Hospital de Santa Maria, Lisbon, Portugal.; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Roussel MF; Department of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, TN, USA.
Boop F; Department of Tumor Cell Biology, St Jude Children's Research Hospital, Memphis, TN, USA.
Chan JA; Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.
Aldinger KA; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Razavi F; Assistance Publique Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Paris, France.
Silvestri E; Surgical Pathology Unit, San Camillo Forlanini Hospital, Rome, Italy.
McLendon RE; Department of Pathology, Duke University, Durham, NC, USA.; Department of Neurosurgery, Duke University, Durham, NC, USA.
Thompson EM; Department of Neurosurgery, Duke University, Durham, NC, USA.
Ansari M; Cansearch Research Platform for Pediatric Oncology and Hematology, Faculty of Medicine, Department of Pediatrics, Gynecology and Obstetrics, University of Geneva, Geneva, Switzerland.; Division of Pediatric Oncology and Hematology, Department of Women, Child and Adolescent, University Geneva Hospitals, Geneva, Switzerland.
Garre ML; U.O. Neurochirurgia, Istituto Giannina Gaslini, Genova, Italy.
Chico F; Department of Neurosurgery, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico.
Eguía P; Department of Neurosurgery, Hospital Infantil de Mexico Federico Gomez, Mexico City, Mexico.
Pérezpeña M; Instituto Nacional De Pediatría de México, Mexico City, Mexico.
Morrissy AS; Charbonneau Cancer Institute, University of Calgary, Calgary, Alberta, Canada.; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Alberta Children's Hospital Research Institute, Calgary, Alberta, Canada.
Cavalli FMG; INSERM U900, Institut Curie, Paris, France.; PSL Research University, Institut Curie, Paris, France.; CBIO-Centre for Computational Biology, PSL Research University, MINES ParisTech, Paris, France.
Wu X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Daniels C; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
Rich JN; UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Jones SJM; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
Moore RA; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Marra MA; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
Huang X; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.
Reimand J; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Sorensen PH; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Molecular Oncology, BC Cancer Agency, Vancouver, British Columbia, Canada.
Wechsler-Reya RJ; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Weiss WA; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Department of Neurology, University of California San Francisco, San Francisco, CA, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Pugh TJ; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Garzia L; Cancer Research Program, McGill University Health Centre Research Institute, Montreal, Quebec, Canada.
Kleinman CL; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Lady Davis Research Institute, Jewish General Hospital, Montreal, Quebec, Canada.
Stein LD; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Adaptive Oncology, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Jabado N; Departments of Pediatrics and Human Genetics, McGill University, Montreal, Quebec, Canada.; The Research Institute of the McGill University Health Center, Montreal, Quebec, Canada.
Malkin D; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Ayrault O; PSL Research University, Université Paris Sud, Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Institut Curie, Orsay, France.
Golden JA; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Ellison DW; Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA.
Doble B; Department of Pediatrics and Child Health and Department of Biochemistry and Medical Genetics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Ramaswamy V; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Division of Haematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, Ontario, Canada.
Werbowetski-Ogilvie TE; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.; CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada.
Suzuki H; Division of Brain Tumor Translational Research, National Cancer Center Research Institute, Tokyo, Japan.
Millen KJ; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.
Taylor MD; The Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. .; Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada. .; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. .; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. .; Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada. .
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Źródło:
Nature [Nature] 2022 Sep; Vol. 609 (7929), pp. 1021-1028. Date of Electronic Publication: 2022 Sep 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*/genetics
Cerebellar Neoplasms*/classification
Cerebellar Neoplasms*/genetics
Cerebellar Neoplasms*/pathology
Medulloblastoma*/classification
Medulloblastoma*/genetics
Medulloblastoma*/pathology
Metencephalon*/embryology
Metencephalon*/pathology
Cell Lineage ; Cerebellum/embryology ; Cerebellum/pathology ; Core Binding Factor alpha Subunits/genetics ; Hedgehog Proteins/metabolism ; Histone Demethylases ; Humans ; Ki-67 Antigen/metabolism ; Muscle Proteins ; Mutation ; Otx Transcription Factors/deficiency ; Otx Transcription Factors/genetics ; Repressor Proteins ; T-Box Domain Proteins/metabolism ; Transcription Factors
Czasopismo naukowe
Tytuł:
Control of cell state transitions.
Autorzy:
Rukhlenko OS; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.
Halasz M; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
Rauch N; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.
Zhernovkov V; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.
Prince T; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.
Wynne K; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.
Maher S; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.
Kashdan E; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.
MacLeod K; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.
Carragher NO; Cancer Research UK Edinburgh Centre, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK.
Kolch W; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
Kholodenko BN; Systems Biology Ireland, School of Medicine, University College Dublin, Dublin, Ireland. .; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland. .; Department of Pharmacology, Yale University School of Medicine, New Haven, USA. .
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Źródło:
Nature [Nature] 2022 Sep; Vol. 609 (7929), pp. 975-985. Date of Electronic Publication: 2022 Sep 14.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*
Models, Biological*
Signal Transduction*
Cell Proliferation ; Datasets as Topic ; Phenotype ; Single-Cell Analysis ; Workflow
Czasopismo naukowe
Tytuł:
Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium.
Autorzy:
Hazim RA; Department of Ophthalmology and Stein Eye Institute, University of California, Los Angeles, California, USA.
Paniagua AE; Department of Ophthalmology and Stein Eye Institute, University of California, Los Angeles, California, USA.
Tang L; Department of Ophthalmology and Stein Eye Institute, University of California, Los Angeles, California, USA.
Yang K; Department of Molecular and Medical Pharmacology, UCLA David Geffen School of Medicine, Los Angeles, California, USA.
Kim KKO; Department of Molecular and Medical Pharmacology, UCLA David Geffen School of Medicine, Los Angeles, California, USA.
Stiles L; Department of Molecular and Medical Pharmacology, UCLA David Geffen School of Medicine, Los Angeles, California, USA; Division of Endocrinology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, California, USA.
Divakaruni AS; Department of Molecular and Medical Pharmacology, UCLA David Geffen School of Medicine, Los Angeles, California, USA.
Williams DS; Department of Ophthalmology and Stein Eye Institute, University of California, Los Angeles, California, USA; Department of Neurobiology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California, USA; Molecular Biology Institute, University of California, Los Angeles, California, USA; Brain Research Institute, University of California, Los Angeles, California, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Sep; Vol. 298 (9), pp. 102286. Date of Electronic Publication: 2022 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Differentiation*/drug effects
Mitochondria*/genetics
Mitochondria*/metabolism
Niacinamide*/pharmacology
Retinal Pigment Epithelium*/cytology
Retinal Pigment Epithelium*/drug effects
Retinal Pigment Epithelium*/metabolism
Animals ; Cell Line ; Glucose/metabolism ; Humans ; Pyruvic Acid/metabolism
Czasopismo naukowe
Tytuł:
An induced pluripotent stem cell t(7;12)(q36;p13) acute myeloid leukemia model shows high expression of MNX1 and a block in differentiation of the erythroid and megakaryocytic lineages.
Autorzy:
Nilsson T; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, University of Gothenburg, Institute of Biomedicine, Gothenburg, Sweden.
Waraky A; Department of Laboratory Medicine, University of Gothenburg, Institute of Biomedicine, Gothenburg, Sweden.
Östlund A; Department of Laboratory Medicine, University of Gothenburg, Institute of Biomedicine, Gothenburg, Sweden.
Li S; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.
Staffas A; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden.
Asp J; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, University of Gothenburg, Institute of Biomedicine, Gothenburg, Sweden.; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden.
Fogelstrand L; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, University of Gothenburg, Institute of Biomedicine, Gothenburg, Sweden.
Abrahamsson J; Department of Pediatrics, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.
Palmqvist L; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, University of Gothenburg, Institute of Biomedicine, Gothenburg, Sweden.
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Źródło:
International journal of cancer [Int J Cancer] 2022 Sep 01; Vol. 151 (5), pp. 770-782. Date of Electronic Publication: 2022 Jun 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation*/genetics
Homeodomain Proteins*/genetics
Induced Pluripotent Stem Cells*/metabolism
Leukemia, Myeloid, Acute*/genetics
Megakaryocyte-Erythroid Progenitor Cells*/physiology
Transcription Factors*/genetics
Child ; Gene Expression/genetics ; Gene Expression/physiology ; Gene Expression Profiling ; Hematopoietic Stem Cells/physiology ; Humans ; Megakaryocytes/physiology ; Translocation, Genetic
Czasopismo naukowe

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