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Wyszukujesz frazę ""Cell Differentiation drug effects"" wg kryterium: Temat


Tytuł :
Development of an In Vitro Screening Platform for the Identification of Partial PPARγ Agonists as a Source for Antidiabetic Lead Compounds
Autorzy :
Christensen, Lars Porskjær
El-Houri, Rime B.
Pokaż więcej
Temat :
Adipocytes/cytology
insulin
QD241-441
Drug Evaluation, Preclinical/methods
Cell Differentiation/drug effects
in silico
In Vitro Techniques
Organic chemistry
Molecular Docking Simulation
Review
screening platform
Computer Simulation
adipocytes
plant extracts
adipocyte differentiation
PPAR gamma/agonists
partial PPARγ agonists
PPARγ transactivation
Thiazolidinediones/chemistry
Hypoglycemic Agents/chemistry
type 2 diabetes
glucose uptake
Gene Expression Regulation/drug effects
Lipid Metabolism/drug effects
Humans
Diabetes Mellitus, Type 2/drug therapy
Źródło :
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Christensen, L P & El-Houri, R B 2018, ' Development of an in vitro screening platform for the identification of partial PPARγ agonists as a source for antidiabetic lead compounds ' Molecules, vol. 23, no. 10, 2431 . https://doi.org/10.3390/molecules23102431
Molecules, Vol 23, Iss 10, p 2431 (2018)
Christensen, L P & El-Houri, R 2018, ' Development of an in vitro screening platform for the identification of partial PPARγ agonists as a source for antidiabetic lead compounds ', Molecules, vol. 23, no. 10, pp. 2431 . https://doi.org/10.3390/molecules23102431
Opis pliku :
application/pdf
Tytuł :
Activation of Group II Metabotropic Glutamate Receptors Increases Proliferation but does not Influence Neuronal Differentiation of a Human Neural Stem Cell Line
Autorzy :
Dindler, Anne
Blaabjerg, Morten
Kamand, Morad
Bogetofte, Helle
Meyer, Morten
Pokaż więcej
Temat :
Neural Stem Cells/drug effects
Neurons/cytology
Amino Acids/pharmacology
Cell Differentiation/drug effects
Glutamic Acid/metabolism
Receptors, Metabotropic Glutamate/agonists
Cell Survival/drug effects
Cyclopropanes/pharmacology
Cell Line
Glycine/analogs & derivatives
Humans
Cell Proliferation/drug effects
Xanthenes/pharmacology
Źródło :
Dindler, A, Blaabjerg, M, Kamand, M, Bogetofte, H & Meyer, M 2018, ' Activation of Group II Metabotropic Glutamate Receptors Increases Proliferation but does not Influence Neuronal Differentiation of a Human Neural Stem Cell Line ', Basic & Clinical Pharmacology & Toxicology, vol. 122, no. 4, pp. 367-372 . https://doi.org/10.1111/bcpt.12920
Opis pliku :
application/pdf
Tytuł :
The GPR120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat
Autorzy :
Schilperoort, Maaike
Shabalina, Irina G
Christian, Mark
van Dam, Andrea D
Hoeke, Geerte
Okolo, Anthony
Hanyaloglu, Aylin C
Dib, Lea H
Mol, Isabel M
Caengprasath, Natarin
Chan, Yi‐Wah
Damak, Sami
Miller, Anne Reifel
Coskun, Tamer
Shimpukade, Bharat
Ulven, Trond
Kooijman, Sander
Rensen, Patrick CN
Pokaż więcej
Temat :
Oxygen Consumption/drug effects
Lipids
Research Article
GPR120
Adiposity/drug effects
06 Biological Sciences
lipid metabolism
Cell Differentiation/drug effects
Models, Biological
Receptors, G-Protein-Coupled/agonists
QH426-470
Mice, Inbred C57BL
Genetics
Cell Respiration/drug effects
Phenylpropionates/pharmacology
Oxidation-Reduction
Animals
Ca
Mitochondria/drug effects
Adipocytes, Brown/cytology
Uncoupling Protein 1/metabolism
Body Weight/drug effects
R5-920
mitochondria
Adipocytes, White/cytology
Glucose/metabolism
RC
brown adipose tissue
Pharmacology & Drug Discovery
Gene Expression Regulation/drug effects
Medicine (General)
11 Medical And Health Sciences
Ca2+
Metabolism
Research Articles
Adipose Tissue, White/drug effects
Adipose Tissue, Brown/drug effects
Biphenyl Compounds/pharmacology
Male
Źródło :
Schilperoort, M, van Dam, A D, Hoeke, G, Shabalina, I G, Okolo, A, Hanyaloglu, A C, Dib, L H, Mol, I M, Caengprasath, N, Chan, Y-W, Damak, S, Miller, A R, Coskun, T, Shimpukade, B, Ulven, T, Kooijman, S, Rensen, P C & Christian, M 2018, ' The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat ', EMBO Molecular Medicine, vol. 10, no. 3, e8047 . https://doi.org/10.15252/emmm.201708047
EMBO Molecular Medicine, Vol 10, Iss 3, Pp n/a-n/a (2018)
Opis pliku :
application/pdf
Tytuł :
Flow velocity-driven differentiation of human mesenchymal stromal cells in silk fibroin scaffolds: A combined experimental and computational approach
Autorzy :
Vetsch, Jolanda Rita
Betts, Duncan Colin
Müller, Ralph
Hofmann, Sandra
Pokaż więcej
Temat :
Primary Cell Culture
Cell Physiology
X-Ray Microtomography
Radiology and Imaging
Tissue Repair
Mesenchymal Stem Cells/cytology
Physical Sciences
Bone Regeneration/physiology
Intercellular Signaling Peptides and Proteins/pharmacology
Medicine(all)
Cell Metabolism
Stress, Mechanical
Biology and Life Sciences
Neuroscience
Physiology
Neuroimaging
Biochemistry, Genetics and Molecular Biology(all)
Biomechanical Phenomena
Tissue Engineering/methods
Computed Axial Tomography
Science
Bioreactors
Agricultural and Biological Sciences(all)
Cell Differentiation
Research Article
Diagnostic Medicine
Time-Lapse Imaging
Classical Mechanics
Continuum Mechanics
Cell Differentiation/drug effects
Diagnostic Radiology
Biomechanics
Bone and Bones/cytology
Osteogenesis
Fluid Dynamics
Bone and Joint Mechanics
Fluid Flow
Fibroins/chemistry
Tomography
Cell Culture Techniques
Physics
Imitation
Fluid Mechanics
Behavior
Tissue Scaffolds
Rheology
Cell Proliferation
Developmental Biology
Animal Behavior
Research and Analysis Methods
Medicine
Cell Biology
Imaging Techniques
Calcification, Physiologic
Cellular Structures and Organelles
Extracellular Matrix/metabolism
Journal Article
Physiological Processes
Medicine and Health Sciences
Humans
Extracellular Matrix
Zoology
Źródło :
PLoS ONE, 12(7). Public Library of Science
PLoS ONE, Vol 12, Iss 7, p e0180781 (2017)
Opis pliku :
application/pdf; application/application/pdf
Tytuł :
Cabozantinib targets bone microenvironment modulating human osteoclast and osteoblast functions.
Autorzy :
Fioramonti, M.
Santini, D.
Iuliani, M.
Ribelli, G.
Manca, P.
Papapietro, N.
Spiezia, F.
Vincenzi, B.
Denaro, V.
Russo, A.
Tonini, G.
Pantano, F.
Pokaż więcej
Temat :
Pyridines -- pharmacology
Osteoclasts -- cytology -- drug effects -- physiology
human primary cells
Sciences bio-médicales et agricoles
Apoptosis
Bone microenvironment
Cabozantinib
Human primary cells
Osteoprotegerin (OPG)
Receptor activator of nuclear factor-kb ligand (RANKL)
Anilides
Blotting, Western
Bone Resorption
Cell Differentiation
Cell Proliferation
Cells, Cultured
Humans
Immunoenzyme Techniques
Osteoblasts
Osteoclasts
Osteogenesis
Osteoprotegerin
Proto-Oncogene Proteins c-met
Pyridines
RANK Ligand
RNA, Messenger
Real-Time Polymerase Chain Reaction
Receptor Activator of Nuclear Factor-kappa B
Reverse Transcriptase Polymerase Chain Reaction
Oncology
musculoskeletal diseases
Bone Resorption -- drug therapy -- metabolism -- pathology
Osteoblasts -- cytology -- drug effects -- physiology
Research Paper
Cell Differentiation -- drug effects
Anilides -- pharmacology
Osteogenesis -- drug effects -- physiology
cabozantinib
Proto-Oncogene Proteins c-met -- genetics -- metabolism
RNA, Messenger -- genetics
bone microenvironment
RANK Ligand -- genetics -- metabolism
Osteoprotegerin -- genetics -- metabolism
osteoprotegerin (OPG)
receptor activator of nuclear factor-kb ligand (RANKL)
Receptor Activator of Nuclear Factor-kappa B -- genetics -- metabolism
Źródło :
8
Opis pliku :
1 full-text file(s): application/pdf
Tytuł :
A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus
Autorzy :
Menon, Madhvi
Blair, Paul A
Isenberg, David A
Mauri, Claudia
Pokaż więcej
Temat :
Adult
Aged
Antigens, CD/metabolism
Antirheumatic Agents/administration & dosage
B-Lymphocytes, Regulatory/drug effects
Cell Communication/drug effects
Cell Differentiation/drug effects
Cells, Cultured
Dendritic Cells/drug effects
Female
Homeostasis/drug effects
Humans
Interferon-gamma/metabolism
Interleukin-10/metabolism
Lupus Erythematosus, Systemic/drug therapy
Male
Middle Aged
Rituximab/administration & dosage
STAT1 Transcription Factor/metabolism
STAT3 Transcription Factor/metabolism
Transcriptional Activation/drug effects
Young Adult
Źródło :
Menon, M, Blair, P A, Isenberg, D A & Mauri, C 2016, ' A Regulatory Feedback between Plasmacytoid Dendritic Cells and Regulatory B Cells Is Aberrant in Systemic Lupus Erythematosus ', Immunity, vol. 44, no. 3, pp. 683-697 . https://doi.org/10.1016/j.immuni.2016.02.012
Opis pliku :
application/pdf
Tytuł :
The GATA1s isoform is normally down-regulated during terminal haematopoietic differentiation and over-expression leads to failure to repress MYB, CCND2 and SKI during erythroid differentiation of K562 cells
Autorzy :
Halsey Christina
Docherty Marie
McNeill Mhairi
Gilchrist Derek
Le Brocq Michelle
Gibson Brenda
Graham Gerard
Pokaż więcej
Temat :
GATA1 transcription factor
Humans
Down syndrome/*genetics/physiopathology
Leukaemia
Megakaryoblastic
Acute/genetics
Dendritic cells
Cell differentiation/*drug effects
Diseases of the blood and blood-forming organs
RC633-647.5
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Źródło :
Journal of Hematology & Oncology, Vol 5, Iss 1, p 45 (2012)
Opis pliku :
electronic resource
Relacje :
http://www.jhoonline.org/content/5/1/45; https://doaj.org/toc/1756-8722
Dostęp URL :
https://doaj.org/article/756f2504bf1d4459aae3787011aa915c
Czasopismo naukowe

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