Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Cell Hypoxia"" wg kryterium: Temat


Tytuł:
Induction of Hypoxic Response in Caco-2 Cells Promote the Expression of Genes Involved in SARS-CoV-2 Endocytosis and Transcytosis.
Autorzy:
Nersisyan SA; Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow, Russia. .; Institute of Molecular Biology (IMB), National Academy of Sciences of the Republic of Armenia, Yerevan, Armenia. .
Pokaż więcej
Źródło:
Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2022 Oct; Vol. 506 (1), pp. 206-209. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*
Endocytosis*
Transcytosis*
Cell Hypoxia*
Humans ; Caco-2 Cells ; MicroRNAs/genetics ; SARS-CoV-2
Czasopismo naukowe
Tytuł:
OTUB1 augments hypoxia signaling via its non-canonical ubiquitination inhibition of HIF-1α during hypoxia adaptation.
Autorzy:
Liu X; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; University of Chinese Academy of Sciences, Beijing, 100049, PR China.; The Innovation of Seed Design, Chinese Academy of Sciences, Wuhan, 430072, PR China.; Hubei Hongshan Laboratory, Wuhan, 430070, PR China.
Deng H; College of Life Science, Wuhan University, Wuhan, 430072, PR China.; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, PR China.
Tang J; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; University of Chinese Academy of Sciences, Beijing, 100049, PR China.
Wang Z; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; University of Chinese Academy of Sciences, Beijing, 100049, PR China.
Zhu C; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; University of Chinese Academy of Sciences, Beijing, 100049, PR China.
Cai X; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; The Innovation of Seed Design, Chinese Academy of Sciences, Wuhan, 430072, PR China.
Rong F; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; University of Chinese Academy of Sciences, Beijing, 100049, PR China.
Chen X; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; University of Chinese Academy of Sciences, Beijing, 100049, PR China.
Sun X; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; University of Chinese Academy of Sciences, Beijing, 100049, PR China.
Jia S; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; University of Chinese Academy of Sciences, Beijing, 100049, PR China.
Ouyang G; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China.; The Innovation of Seed Design, Chinese Academy of Sciences, Wuhan, 430072, PR China.
Li W; College of Life Science, Wuhan University, Wuhan, 430072, PR China. .; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072, PR China. .
Xiao W; State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, PR China. .; University of Chinese Academy of Sciences, Beijing, 100049, PR China. .; The Innovation of Seed Design, Chinese Academy of Sciences, Wuhan, 430072, PR China. .; Hubei Hongshan Laboratory, Wuhan, 430070, PR China. .
Pokaż więcej
Źródło:
Cell death & disease [Cell Death Dis] 2022 Jun 22; Vol. 13 (6), pp. 560. Date of Electronic Publication: 2022 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Hypoxia*/physiology
Deubiquitinating Enzymes*/genetics
Deubiquitinating Enzymes*/metabolism
Hypoxia-Inducible Factor 1, alpha Subunit*/genetics
Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism
Signal Transduction*
Humans ; Ubiquitination
Czasopismo naukowe
Tytuł:
Long Noncoding RNA SCIRT Promotes HUVEC Angiogenesis via Stabilizing VEGFA mRNA Induced by Hypoxia.
Autorzy:
Gao L; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Yang J; Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, NY 10032, USA.
Li Y; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Liu K; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Sun H; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Tang J; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Xia Z; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Zhang L; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Hu Z; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.; Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, NY 10032, USA.
Pokaż więcej
Źródło:
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2022 Jun 03; Vol. 2022, pp. 9102978. Date of Electronic Publication: 2022 Jun 03 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Cell Hypoxia*
Neovascularization, Pathologic*
RNA, Long Noncoding*/genetics
Vascular Endothelial Growth Factor A*/genetics
Vascular Endothelial Growth Factor A*/metabolism
Cell Proliferation/genetics ; Human Umbilical Vein Endothelial Cells ; Humans ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Hypoxia Regulates the Self-Renewal of Endometrial Mesenchymal Stromal/Stem-like Cells via Notch Signaling.
Autorzy:
Zhang S; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; Shenzhen Key Laboratory of Fertility Regulation, The University of Hong Kong Shenzhen Hospital, Shenzhen 518000, China.
Chan RWS; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; Shenzhen Key Laboratory of Fertility Regulation, The University of Hong Kong Shenzhen Hospital, Shenzhen 518000, China.
Ng EHY; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; Shenzhen Key Laboratory of Fertility Regulation, The University of Hong Kong Shenzhen Hospital, Shenzhen 518000, China.
Yeung WSB; Department of Obstetrics and Gynaecology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong 999077, China.; Shenzhen Key Laboratory of Fertility Regulation, The University of Hong Kong Shenzhen Hospital, Shenzhen 518000, China.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Apr 21; Vol. 23 (9). Date of Electronic Publication: 2022 Apr 21.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Hypoxia*/physiology
Endometrium*/metabolism
Mesenchymal Stem Cells*/metabolism
Animals ; Female ; Hypoxia/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mice ; Receptors, Notch/metabolism ; Signal Transduction ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł:
Hypoxia pretreatment improves the therapeutic potential of bone marrow mesenchymal stem cells in hindlimb ischemia via upregulation of NRG-1.
Autorzy:
Peng X; Department of Vascular Surgery, The Third Provincial People's Hospital of Henan Province, No. 198 Funiu Road, Zhengzhou, 450000, People's Republic of China.
Liang B; Department of Vascular Surgery, The Third Provincial People's Hospital of Henan Province, No. 198 Funiu Road, Zhengzhou, 450000, People's Republic of China.
Wang H; Department of Vascular Surgery, The Third Provincial People's Hospital of Henan Province, No. 198 Funiu Road, Zhengzhou, 450000, People's Republic of China.
Hou J; Department of Vascular Surgery, The Third Provincial People's Hospital of Henan Province, No. 198 Funiu Road, Zhengzhou, 450000, People's Republic of China.
Yuan Q; Department of Vascular Surgery, The Third Provincial People's Hospital of Henan Province, No. 198 Funiu Road, Zhengzhou, 450000, People's Republic of China. .
Pokaż więcej
Źródło:
Cell and tissue research [Cell Tissue Res] 2022 Apr; Vol. 388 (1), pp. 105-116. Date of Electronic Publication: 2022 Jan 29.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Hypoxia*
Ischemia*/therapy
Mesenchymal Stem Cell Transplantation*
Neuregulin-1*/genetics
Animals ; Bone Marrow Cells/metabolism ; Cells, Cultured ; Hindlimb ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Mesenchymal Stem Cells/cytology ; Mice ; Neovascularization, Physiologic ; Phosphatidylinositol 3-Kinases/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł:
Urolithin B, a Gut Microbiota Metabolite, Reduced Susceptibility to Myocardial Arrhythmic Predisposition after Hypoxia.
Autorzy:
Huang X; Department of Cardiology, The First Affiliated Hospital of Nanchang University, Nanchang 330008, China.; Department of Cardiology, The First Hospital of Nanchang, The Third Affiliated Hospital of Nanchang University, Affiliated Hospital of Sun Yat-sen University, Nanchang 330008, China.
Gao H; Department of Cardiology, The First Hospital of Nanchang, The Third Affiliated Hospital of Nanchang University, Affiliated Hospital of Sun Yat-sen University, Nanchang 330008, China.
Jiang X; Department of Cardiology, The First Hospital of Nanchang, The Third Affiliated Hospital of Nanchang University, Affiliated Hospital of Sun Yat-sen University, Nanchang 330008, China.
Zheng Z; Department of Cardiology, The First Affiliated Hospital of Nanchang University, Nanchang 330008, China.
Pokaż więcej
Źródło:
Disease markers [Dis Markers] 2022 Feb 08; Vol. 2022, pp. 6517266. Date of Electronic Publication: 2022 Feb 08 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Cell Hypoxia*
Apoptosis/*drug effects
Coumarins/*pharmacology
Myocytes, Cardiac/*drug effects
Animals ; Arrhythmias, Cardiac/prevention & control ; Cells, Cultured ; Coumarins/metabolism ; Disease Susceptibility ; Gastrointestinal Microbiome/physiology ; Mice
Czasopismo naukowe
Tytuł:
Diosmetin inhibits apoptosis and activates AMPK-induced autophagy in myocardial damage under hypoxia environment.
Autorzy:
He WS; Department of Cardiology, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia Autonomous Region, China.
Wu Y; Department of Cardiology, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia Autonomous Region, China.
Ren MJ; Department of Cardiology, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia Autonomous Region, China.
Yu ZY; Department of Cardiology, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia Autonomous Region, China.
Zhao XS; Department of Cardiology, Inner Mongolia People's Hospital, Hohhot, Inner Mongolia Autonomous Region, China.
Pokaż więcej
Źródło:
The Kaohsiung journal of medical sciences [Kaohsiung J Med Sci] 2022 Feb; Vol. 38 (2), pp. 139-148. Date of Electronic Publication: 2021 Oct 28.
Typ publikacji:
Journal Article
MeSH Terms:
Autophagy*
Cell Hypoxia*
AMP-Activated Protein Kinase Kinases/*drug effects
AMP-Activated Protein Kinase Kinases/*physiology
Apoptosis/*drug effects
Flavonoids/*pharmacology
Myocytes, Cardiac/*metabolism
Myocytes, Cardiac/*pathology
Animals ; Cells, Cultured ; Rats
Czasopismo naukowe
Tytuł:
Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cells.
Autorzy:
Xiao L; Animal Science and Technology College, Beijing University of Agriculture, Beijing, China.
Wang Z; Animal Science and Technology College, Beijing University of Agriculture, Beijing, China.
Lu N; Animal Science and Technology College, Beijing University of Agriculture, Beijing, China.
Wei H; Beijing Detector Dog Developing Facility GACC, Beijing, China.
Kang J; Guangdong Polytechnic of Science and Trade, Guangdong, China.
Yuan M; Beijing Changping Animal Disease Prevention and Control Center, Beijing, China.
Sheng X; Animal Science and Technology College, Beijing University of Agriculture, Beijing, China.
Qi X; Animal Science and Technology College, Beijing University of Agriculture, Beijing, China.
Xing K; Animal Science and Technology College, Beijing University of Agriculture, Beijing, China.
Guo Y; Animal Science and Technology College, Beijing University of Agriculture, Beijing, China.
Wang X; Animal Science and Technology College, Beijing University of Agriculture, Beijing, China. Electronic address: .
Zhao J; National Grazing Headquarter, Beijing, China.
Gao Y; People's Government of Xiacang Town, Jizhou District, Tianjin, China.
Ni H; Animal Science and Technology College, Beijing University of Agriculture, Beijing, China. Electronic address: .
Pokaż więcej
Źródło:
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2022 Feb; Vol. 216, pp. 106041. Date of Electronic Publication: 2021 Dec 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Hypoxia/*physiology
Dihydrotestosterone/*pharmacology
Sertoli Cells/*drug effects
Animals ; Antifibrotic Agents/pharmacology ; Cell Hypoxia/drug effects ; Cells, Cultured ; Dogs ; Fibrosis/pathology ; Fibrosis/prevention & control ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Male ; Scrotum/drug effects ; Scrotum/metabolism ; Scrotum/pathology ; Sertoli Cells/metabolism ; Sertoli Cells/pathology ; Signal Transduction/drug effects ; Smad Proteins/antagonists & inhibitors ; Smad Proteins/metabolism ; Testis/drug effects ; Testis/metabolism ; Testis/pathology ; Transforming Growth Factor beta/antagonists & inhibitors ; Transforming Growth Factor beta/metabolism
Czasopismo naukowe
Tytuł:
Hypoxia-induced HIF1α activation regulates small extracellular vesicle release in human embryonic kidney cells.
Autorzy:
Muñiz-García A; Department of Molecular Physiology and Cell Signalling (Formerly Dpt. Cellular and Molecular Physiology), The University of Liverpool, Liverpool, L69 3BX, UK.; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 13, 08028, Barcelona, Spain.
Romero M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 13, 08028, Barcelona, Spain.; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain.; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain.
Falcόn-Perez JM; Exosomes Laboratory, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), 48160, Derio, Bizkaia, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, 28029, Madrid, Spain.; IKERBASQUE, Basque Foundation for Science, 48015, Bilbao, Bizkaia, Spain.
Murray P; Department of Molecular Physiology and Cell Signalling (Formerly Dpt. Cellular and Molecular Physiology), The University of Liverpool, Liverpool, L69 3BX, UK.
Zorzano A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 13, 08028, Barcelona, Spain.; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain.; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain.
Mora S; Department of Molecular Physiology and Cell Signalling (Formerly Dpt. Cellular and Molecular Physiology), The University of Liverpool, Liverpool, L69 3BX, UK. .; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Av. Diagonal 643, 08028, Barcelona, Spain. .; Institute of Biomedicine, University of Barcelona, 08028, Barcelona, Spain. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2022 Jan 27; Vol. 12 (1), pp. 1443. Date of Electronic Publication: 2022 Jan 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Hypoxia*
Epithelial Cells/*metabolism
Extracellular Vesicles/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Embryo, Mammalian ; Epithelial Cells/cytology ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Kidney/cytology
Czasopismo naukowe
Tytuł:
hsa_circWDR37_016 Regulates Hypoxia-Induced Proliferation of Pulmonary Arterial Smooth Muscle Cells.
Autorzy:
Li SS; School of Medicine, Nankai University, Tianjin, China.
Liang S; School of Medicine, Nankai University, Tianjin, China.; Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, China.; Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin, China.
Long Y; School of Medicine, Nankai University, Tianjin, China.
Chen X; School of Medicine, Nankai University, Tianjin, China.; Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, China.; Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin, China.
Jin X; School of Medicine, Nankai University, Tianjin, China.; Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, China.; Tianjin Key Laboratory of Human Development and Reproductive Regulation, Tianjin, China.
Pokaż więcej
Źródło:
Cardiovascular therapeutics [Cardiovasc Ther] 2022 Jan 17; Vol. 2022, pp. 7292034. Date of Electronic Publication: 2022 Jan 17 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Cell Hypoxia*
Myocytes, Smooth Muscle/*cytology
RNA, Circular/*genetics
Cell Movement ; Cell Proliferation ; Cells, Cultured ; Humans ; MicroRNAs/genetics ; Pulmonary Artery/cytology
Czasopismo naukowe
Tytuł:
Identification of a novel native peptide derived from 60S ribosomal protein L23a that translationally regulates p53 to reduce myocardial ischemia-reperfusion.
Autorzy:
Yin A; Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China.
Feng M; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Zhang L; Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China.
Cheng Z; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Li Y; Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China. Electronic address: .
Qian L; Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China; Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. Electronic address: .
Pokaż więcej
Źródło:
Pharmacological research [Pharmacol Res] 2022 Jan; Vol. 175, pp. 105988. Date of Electronic Publication: 2021 Nov 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Hypoxia*
Myocytes, Cardiac/*metabolism
Peptides/*metabolism
Ribosomal Proteins/*metabolism
Tumor Suppressor Protein p53/*metabolism
Animals ; Cells, Cultured ; Male ; Myocardial Reperfusion Injury ; Peptides/chemistry ; Rats, Sprague-Dawley ; Ribosomal Proteins/chemistry ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł:
ISGylation directly modifies hypoxia-inducible factor-2α and enhances its polysome association.
Autorzy:
Melanson G; Department of Molecular and Cellular Biology, University of Guelph, Canada.
Du Bois AC; Department of Molecular and Cellular Biology, University of Guelph, Canada.
Webster C; Department of Molecular and Cellular Biology, University of Guelph, Canada.
Uniacke J; Department of Molecular and Cellular Biology, University of Guelph, Canada.
Pokaż więcej
Źródło:
FEBS letters [FEBS Lett] 2022 Nov; Vol. 596 (21), pp. 2834-2850. Date of Electronic Publication: 2022 Sep 02.
Typ publikacji:
Journal Article
MeSH Terms:
Basic Helix-Loop-Helix Transcription Factors*/genetics
Basic Helix-Loop-Helix Transcription Factors*/immunology
Hypoxia*/genetics
Hypoxia*/immunology
Polyribosomes*/genetics
Polyribosomes*/immunology
Humans ; Cell Hypoxia/genetics ; Cell Hypoxia/immunology ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/immunology ; Interferons/genetics ; Interferons/immunology
Czasopismo naukowe
Tytuł:
Long non-coding RNA histone deacetylase 4 antisense RNA 1 (HDAC4-AS1) inhibits HDAC4 expression in human ARPE-19 cells with hypoxic stress.
Autorzy:
Pan J; Department of Ophthalmology, ZiBo Central Hospital, Zibo City, People's Republic of China.
Zhao L; Department of Ophthalmology, ZiBo Central Hospital, Zibo City, People's Republic of China.
Pokaż więcej
Źródło:
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 2228-2237.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Hypoxia*/genetics
Cell Hypoxia*/physiology
Histone Deacetylases*/genetics
Histone Deacetylases*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Repressor Proteins*/genetics
Repressor Proteins*/metabolism
Cell Line ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Retinal Pigment Epithelium/cytology
Czasopismo naukowe
Tytuł:
Hypoxia-responsive nanocarriers for chemotherapy sensitization via dual-mode inhibition of hypoxia-inducible factor-1 alpha.
Autorzy:
Wang Z; School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China.
Mu X; School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China.
Yang Q; School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China.
Luo J; School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China.
Zhao Y; School of Pharmaceutical Science & Technology, Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin University, Tianjin 300072, China. Electronic address: .
Pokaż więcej
Źródło:
Journal of colloid and interface science [J Colloid Interface Sci] 2022 Dec 15; Vol. 628 (Pt B), pp. 106-115. Date of Electronic Publication: 2022 Aug 12.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/pharmacology
Nitroimidazoles*/pharmacology
Female ; Humans ; Micelles ; Caspase 3 ; Cell Line, Tumor ; Cell Hypoxia/physiology ; Sorafenib/pharmacology ; Dicumarol/pharmacology ; Cytochromes c ; NAD/pharmacology ; Aspartic Acid ; NADP/pharmacology ; Thioredoxins/pharmacology ; Polymers/pharmacology ; Hypoxia ; Oxygen ; Phosphates ; Polyethylene Glycols/pharmacology ; Glutathione/pharmacology ; Quinones/pharmacology
Czasopismo naukowe
Tytuł:
Mesenchymal stem cells-derived HIF-1α-overexpressed extracellular vesicles ameliorate hypoxia-induced pancreatic β cell apoptosis and senescence through activating YTHDF1-mediated protective autophagy.
Autorzy:
Fang J; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China. Electronic address: .
Chen Z; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China. Electronic address: .
Lai X; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
Yin W; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
Guo Y; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
Zhang W; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
Ma J; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
Li G; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
Zhang L; Department of Organ Transplantation, The Second Affiliated Hospital of Guangzhou Medical University, Yayun South Road No. 63, Guangzhou 510000, Guangdong, China.
Pokaż więcej
Źródło:
Bioorganic chemistry [Bioorg Chem] 2022 Dec; Vol. 129, pp. 106194. Date of Electronic Publication: 2022 Oct 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin-Secreting Cells*/metabolism
Extracellular Vesicles*/metabolism
Mesenchymal Stem Cells*/metabolism
Humans ; Cell Hypoxia ; Autophagy ; Apoptosis ; Hypoxia/metabolism ; Methyltransferases/metabolism ; RNA-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of hypoxia-induced HIF-1α-mediated autophagy enhances the in vitro antitumor activity of rhein in pancreatic cancer cells.
Autorzy:
Yao C; The Medical School, Nankai University, Tianjin, China.; Department of Oncology, Nanyang First People's Hospital, Henan, China.
Wang F; The Medical School, Nankai University, Tianjin, China.; The Laboratory of Acute Abdomen Disease Associated Organ Injury and Repair, Nankai Hospital Affiliated to Nankai University, Tianjin, China.
Pokaż więcej
Źródło:
Journal of applied toxicology : JAT [J Appl Toxicol] 2022 Dec; Vol. 42 (12), pp. 1937-1947. Date of Electronic Publication: 2022 Jul 25.
Typ publikacji:
Journal Article
MeSH Terms:
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Humans ; Cell Hypoxia ; Cell Line, Tumor ; Autophagy ; Hypoxia ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Tumor Microenvironment
SCR Disease Name:
Pancreatic Carcinoma
Czasopismo naukowe
Tytuł:
Activation of PGRN/MAPK axis stimulated by the hypoxia-conditioned mesenchymal stem cell-derived HIF-1α facilitates osteosarcoma progression.
Autorzy:
Shang C; Department of the Second Hand Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Ou X; Department of the First Hand Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Zhang H; Department of the Second Hand Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Wei D; Department of the First Hand Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Wang Q; Department of the First Hand Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China.
Li G; Department of the First Hand Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, China. Electronic address: .
Pokaż więcej
Źródło:
Experimental cell research [Exp Cell Res] 2022 Dec 01; Vol. 421 (1), pp. 113373. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article
MeSH Terms:
Osteosarcoma*/pathology
Mesenchymal Stem Cells*
Bone Neoplasms*/genetics
Bone Neoplasms*/metabolism
Humans ; Progranulins/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Skatole/metabolism ; Cell Hypoxia/physiology ; Cell Proliferation ; Hypoxia/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Zinc and hypoxic preconditioning: a strategy to enhance the functionality and therapeutic potential of bone marrow-derived mesenchymal stem cells.
Autorzy:
Rizvi SFA; Ghulam Muhammad Mahar Medical College Sukkur at Shaheed Mohtarma Benazir Bhutto Medical University Larkana, Larkana, 77150, Pakistan.; Ziauddin University, Clifton, Karachi, 74700, Pakistan.
Wasim B; Ziauddin University, Clifton, Karachi, 74700, Pakistan.
Usman S; Ziauddin University, Clifton, Karachi, 74700, Pakistan.
Borges KJJ; Ziauddin University, Clifton, Karachi, 74700, Pakistan.
Sahibdad I; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Centre for Chemical and Biological Sciences, Karachi, 75270, Pakistan.
Salim A; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Centre for Chemical and Biological Sciences, Karachi, 75270, Pakistan.
Khan I; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Centre for Chemical and Biological Sciences, Karachi, 75270, Pakistan. .; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan. .
Pokaż więcej
Źródło:
Molecular and cellular biochemistry [Mol Cell Biochem] 2022 Dec; Vol. 477 (12), pp. 2735-2749. Date of Electronic Publication: 2022 May 24.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Marrow Cells*/metabolism
Mesenchymal Stem Cells*/metabolism
Humans ; Aged ; Zinc/pharmacology ; Zinc/metabolism ; Bone Marrow ; Cell Hypoxia ; Cells, Cultured ; Cell Proliferation ; Hypoxia/metabolism
Czasopismo naukowe
Tytuł:
Fabrication of a Polymeric Inhibitor of Proximal Metabolic Enzymes in Hypoxia for Synergistic Inhibition of Cancer Cell Proliferation, Survival, and Migration.
Autorzy:
Koba Y; Division of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka565-0871, Japan.
Nakamoto M; Division of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka565-0871, Japan.
Matsusaki M; Division of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka565-0871, Japan.
Pokaż więcej
Źródło:
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2022 Nov 23; Vol. 14 (46), pp. 51790-51797. Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Neoplasm*/metabolism
Neoplasms*
Humans ; Cell Hypoxia ; Cell Proliferation ; Hypoxia ; Polymers/pharmacology ; Polymers/metabolism ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature.
Autorzy:
Lombardi O; NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, UK.
Li R; NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, UK.
Halim S; NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, UK.
Choudhry H; Department of Biochemistry, Faculty of Science, Center of Innovation in Personalized Medicine, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Ratcliffe PJ; Ludwig Institute for Cancer Research, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, UK; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
Mole DR; NDM Research Building, University of Oxford, Old Road Campus, Headington, Oxford OX3 7FZ, UK. Electronic address: .
Pokaż więcej
Źródło:
Cell reports [Cell Rep] 2022 Nov 15; Vol. 41 (7), pp. 111652.
Typ publikacji:
Journal Article
MeSH Terms:
Neoplasms*/genetics
Humans ; Transcription Factors/metabolism ; Tumor Microenvironment/genetics ; Cell Hypoxia/genetics ; Hypoxia/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies

Prześlij opinię

Twoje opinie są dla nas bardzo ważne i mogą być niezwykle pomocne w pokazaniu nam, gdzie możemy dokonać ulepszeń. Bylibyśmy bardzo wdzięczni za poświęcenie kilku chwil na wypełnienie krótkiego formularza.

Formularz