Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Cell Hypoxia"" wg kryterium: Temat


Tytuł :
Real-Time Monitoring the Effect of Cytopathic Hypoxia on Retinal Pigment Epithelial Barrier Functionality Using Electric Cell-Substrate Impedance Sensing (ECIS) Biosensor Technology.
Autorzy :
Guerra MH; Department of Ophthalmology, Visual, and Anatomical Sciences, School of Medicine, Wayne State University, 540 East Canfield, Gordon Scott Hall (room 7133), Detroit, MI 48201, USA.
Yumnamcha T; Department of Ophthalmology, Visual, and Anatomical Sciences, School of Medicine, Wayne State University, 540 East Canfield, Gordon Scott Hall (room 7133), Detroit, MI 48201, USA.
Ebrahim AS; Department of Ophthalmology, Visual, and Anatomical Sciences, School of Medicine, Wayne State University, 540 East Canfield, Gordon Scott Hall (room 7133), Detroit, MI 48201, USA.
Berger EA; Department of Ophthalmology, Visual, and Anatomical Sciences, School of Medicine, Wayne State University, 540 East Canfield, Gordon Scott Hall (room 7133), Detroit, MI 48201, USA.
Singh LP; Department of Ophthalmology, Visual, and Anatomical Sciences, School of Medicine, Wayne State University, 540 East Canfield, Gordon Scott Hall (room 7133), Detroit, MI 48201, USA.
Ibrahim AS; Department of Ophthalmology, Visual, and Anatomical Sciences, School of Medicine, Wayne State University, 540 East Canfield, Gordon Scott Hall (room 7133), Detroit, MI 48201, USA.; Department of Pharmacology, School of Medicine, Wayne State University, 540 East Canfield, Gordon Scott Hall (room 7133), Detroit, MI 48201, USA.; Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 27; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 27.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*/drug effects
Cell Hypoxia*/physiology
Biosensing Techniques/*methods
Cobalt/*pharmacology
Retinal Pigment Epithelium/*cytology
Retinal Pigment Epithelium/*physiology
Biosensing Techniques/instrumentation ; Cell Adhesion ; Cell Line ; Cell Survival/drug effects ; Cell Survival/physiology ; Cobalt/administration & dosage ; Dose-Response Relationship, Drug ; Electric Impedance ; Electrodes ; Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; Retinal Pigment Epithelium/drug effects ; Zonula Occludens-1 Protein/metabolism
Czasopismo naukowe
Tytuł :
Role of indoleamine 2,3-dioxygenase in ischemia-reperfusion injury of renal tubular epithelial cells.
Autorzy :
Eleftheriadis T; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Pissas G; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Golfinopoulos S; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Liakopoulos V; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Stefanidis I; Department of Nephrology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.
Pokaż więcej
Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Jun; Vol. 23 (6). Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*
Epithelial Cells/*metabolism
Indoleamine-Pyrrole 2,3,-Dioxygenase/*metabolism
Kidney Tubules, Proximal/*cytology
Activating Transcription Factor 3/metabolism ; Activating Transcription Factor 4/metabolism ; Animals ; Apoptosis ; Azo Compounds/pharmacology ; CCAAT-Enhancer-Binding Proteins/metabolism ; Cells, Cultured ; Enzyme Inhibitors/pharmacology ; Epithelial Cells/drug effects ; Ferroptosis ; Indoleamine-Pyrrole 2,3,-Dioxygenase/antagonists & inhibitors ; Mice ; Mice, Inbred C57BL ; Protein-Serine-Threonine Kinases/metabolism ; Pyrazoles/pharmacology ; Reactive Oxygen Species/metabolism ; Receptors, Aryl Hydrocarbon/antagonists & inhibitors ; Receptors, Aryl Hydrocarbon/metabolism
Czasopismo naukowe
Tytuł :
Mangiferin inhibits cell migration and angiogenesis via PI3K/AKT/mTOR signaling in high glucose‑ and hypoxia‑induced RRCECs.
Autorzy :
Shi J; Department of Ophthalmology, The People's Hospital of Deyang City, Deyang, Sichuan 618000, P.R. China.
Lv H; Department of Ophthalmology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, P.R. China.
Tang C; Department of Ophthalmology, The People's Hospital of Deyang City, Deyang, Sichuan 618000, P.R. China.
Li Y; Department of Ophthalmology, The People's Hospital of Deyang City, Deyang, Sichuan 618000, P.R. China.
Huang J; Department of Ophthalmology, The People's Hospital of Deyang City, Deyang, Sichuan 618000, P.R. China.
Zhang H; Department of Ophthalmology, The People's Hospital of Deyang City, Deyang, Sichuan 618000, P.R. China.
Pokaż więcej
Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Jun; Vol. 23 (6). Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*
Neovascularization, Physiologic*
Endothelial Cells/*metabolism
Phosphatidylinositol 3-Kinases/*metabolism
Retinal Vessels/*cytology
Xanthones/*pharmacology
Animals ; Cell Movement ; Cells, Cultured ; Endothelial Cells/drug effects ; Endothelial Cells/physiology ; Glucose/deficiency ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Costunolide attenuates oxygen‑glucose deprivation/reperfusion‑induced mitochondrial‑mediated apoptosis in PC12 cells.
Autorzy :
Meng L; Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region 750004, P.R. China.
Ma H; Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region 750004, P.R. China.
Meng J; Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region 750004, P.R. China.
Li T; Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region 750004, P.R. China.
Zhu Y; Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region 750004, P.R. China.
Zhao Q; Key Laboratory of Hui Ethnic Medicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region 750004, P.R. China.
Pokaż więcej
Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Jun; Vol. 23 (6). Date of Electronic Publication: 2021 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*
Apoptosis/*drug effects
Glucose/*deficiency
Mitochondria/*metabolism
Neuroprotective Agents/*pharmacology
Sesquiterpenes/*pharmacology
Animals ; Calcium/metabolism ; Caspases/metabolism ; L-Lactate Dehydrogenase/metabolism ; Membrane Potential, Mitochondrial ; PC12 Cells ; Rats
Czasopismo naukowe
Tytuł :
HIF1α-Regulated Expression of the Fatty Acid Binding Protein Family Is Important for Hypoxic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.
Autorzy :
Singh RK; Department of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Bose D; Department of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Robertson ES; Department of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA .; The Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Pokaż więcej
Źródło :
Journal of virology [J Virol] 2021 May 24; Vol. 95 (12). Date of Electronic Publication: 2021 May 24 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cell Hypoxia*
Fatty Acid-Binding Protein 7/*genetics
Fatty Acid-Binding Proteins/*genetics
Herpesvirus 8, Human/*physiology
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Tumor Suppressor Proteins/*genetics
Amino Acids/metabolism ; Antigens, Viral/genetics ; Antigens, Viral/metabolism ; Cell Line, Tumor ; Fatty Acid-Binding Protein 7/metabolism ; Fatty Acid-Binding Proteins/metabolism ; Fatty Acids/metabolism ; Gene Expression Regulation ; Gene Knockdown Techniques ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; RNA Interference ; Receptors, Chemokine/genetics ; Receptors, Chemokine/metabolism ; Tumor Suppressor Proteins/metabolism ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Virus Activation
Czasopismo naukowe
Tytuł :
Glioblastoma cell line shows phenotypes of cancer stem cells in hypoxic microenvironment of spheroids.
Autorzy :
Ohnishi K; Department of Biol, Ibaraki Prefectural University of Health Sciences, Japan. Electronic address: .
Tani T; National Institute of Radiological Sciences Hospital, Japan.
Tojo N; Department of Biol, Ibaraki Prefectural University of Health Sciences, Japan.
Sagara JI; Department of Biochem, Ibaraki Prefectural University of Health Sciences, Japan.
Pokaż więcej
Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Mar 26; Vol. 546, pp. 150-154. Date of Electronic Publication: 2021 Feb 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia*
Models, Biological*
Tumor Microenvironment*
Glioblastoma/*pathology
Neoplastic Stem Cells/*metabolism
Neoplastic Stem Cells/*pathology
Spheroids, Cellular/*metabolism
Spheroids, Cellular/*pathology
AC133 Antigen/metabolism ; Cell Culture Techniques ; Cell Line, Tumor ; Cell Movement ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Flow Cytometry ; Genes, Reporter ; Humans ; Hydrogen-Ion Concentration ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Neoplastic Stem Cells/drug effects ; Phenotype ; Spheroids, Cellular/drug effects ; Spheroids, Cellular/radiation effects ; Temozolomide/pharmacology ; X-Rays
Czasopismo naukowe
Tytuł :
Quantitative Proteomic Approach Reveals Altered Metabolic Pathways in Response to the Inhibition of Lysine Deacetylases in A549 Cells under Normoxia and Hypoxia.
Autorzy :
Martín-Bernabé A; LBFA et BEeSy, Université Grenoble Alpes, Inserm, U1055, CHU Grenoble Alpes, PROMETHEE Proteomic Platform, 38000 Grenoble, France.; PROMETHEE Proteomic Platform, TIMC-IMAG, Université Grenoble Alpes, CNRS, Grenoble INP, CHU Grenoble Alpes, 38000 Grenoble, France.; Department of Biochemistry and Molecular Biomedicine, Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, 08028 Barcelona, Spain.; Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, 17164 Solna, Sweden.
Tarragó-Celada J; Department of Biochemistry and Molecular Biomedicine, Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, 08028 Barcelona, Spain.
Cunin V; LBFA et BEeSy, Université Grenoble Alpes, Inserm, U1055, CHU Grenoble Alpes, PROMETHEE Proteomic Platform, 38000 Grenoble, France.; PROMETHEE Proteomic Platform, TIMC-IMAG, Université Grenoble Alpes, CNRS, Grenoble INP, CHU Grenoble Alpes, 38000 Grenoble, France.
Michelland S; LBFA et BEeSy, Université Grenoble Alpes, Inserm, U1055, CHU Grenoble Alpes, PROMETHEE Proteomic Platform, 38000 Grenoble, France.; PROMETHEE Proteomic Platform, TIMC-IMAG, Université Grenoble Alpes, CNRS, Grenoble INP, CHU Grenoble Alpes, 38000 Grenoble, France.
Cortés R; Department of Biochemistry and Molecular Biomedicine, Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, 08028 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.
Poignant J; Reckonect, Institute for Advanced Biosciences-IAB, Université Grenoble Alpes, Inserm, UMR_S 1209/CNRS UMR 5309, 38000 Grenoble, France.
Boyault C; Reckonect, Institute for Advanced Biosciences-IAB, Université Grenoble Alpes, Inserm, UMR_S 1209/CNRS UMR 5309, 38000 Grenoble, France.
Rachidi W; SyMMES/CIBEST, Université Grenoble Alpes, UMR 5819 UGA-CNRS-CEA, 38000 Grenoble, France.; BIG-BGE, Université Grenoble Alpes, CEA, Inserm, U1038, 38000 Grenoble, France.
Bourgoin-Voillard S; LBFA et BEeSy, Université Grenoble Alpes, Inserm, U1055, CHU Grenoble Alpes, PROMETHEE Proteomic Platform, 38000 Grenoble, France.; PROMETHEE Proteomic Platform, TIMC-IMAG, Université Grenoble Alpes, CNRS, Grenoble INP, CHU Grenoble Alpes, 38000 Grenoble, France.
Cascante M; Department of Biochemistry and Molecular Biomedicine, Institute of Biomedicine of Universitat de Barcelona, Faculty of Biology, Universitat de Barcelona, 08028 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.; Metabolomics Node at Spanish National Bioinformatics Institute (INB-ISCIII-ES-ELIXIR), Institute of Health Carlos III (ISCIII), 28029 Madrid, Spain.
Seve M; LBFA et BEeSy, Université Grenoble Alpes, Inserm, U1055, CHU Grenoble Alpes, PROMETHEE Proteomic Platform, 38000 Grenoble, France.; PROMETHEE Proteomic Platform, TIMC-IMAG, Université Grenoble Alpes, CNRS, Grenoble INP, CHU Grenoble Alpes, 38000 Grenoble, France.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 25; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*
Carcinoma, Non-Small-Cell Lung/*metabolism
Histone Deacetylase Inhibitors/*pharmacology
Histone Deacetylases/*metabolism
Lung Neoplasms/*metabolism
Oxygen/*chemistry
A549 Cells ; Apoptosis ; Humans ; Lysine/chemistry ; Machine Learning ; Metabolic Networks and Pathways ; Oxidative Phosphorylation ; Proteome/metabolism ; Proteomics/methods ; Proto-Oncogene Proteins p21(ras)/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Fabrication of Adipose-Derived Stem Cell-Based Self-Assembled Scaffold under Hypoxia and Mechanical Stimulation for Urethral Tissue Engineering.
Autorzy :
Rashidbenam Z; Centre for Tissue Engineering and Regenerative Medicine, Universiti Kebangsaan Malaysia Medical Centre, 12th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Jasman MH; Clinical Skills Learning and Simulation Unit, Department of Medical Education, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Tan GH; Urology Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, 8th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Goh EH; Urology Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, 8th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Fam XI; Urology Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, 8th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Ho CCK; School of Medicine, Taylor's University, No. 1 Jalan Taylor's, Subang Jaya 47500, Selangor Darul Ehsan, Malaysia.
Zainuddin ZM; Urology Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, 8th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Rajan R; Minimally Invasive Upper Gastrointestinal and Bariatric Surgery Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, 8th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Rani RA; Arthoplasty Unit, Department of Orthopaedics and Traumatology Surgery, Universiti Kebangsaan Malaysia Medical Centre, 9th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Nor FM; Plastic and Reconstructive Surgery Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, Clinical Block, 8th Floor, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Shuhaili MA; Minimally Invasive Upper Gastrointestinal and Bariatric Surgery Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, 8th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Kosai NR; Minimally Invasive Upper Gastrointestinal and Bariatric Surgery Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, 8th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Imran FH; Plastic and Reconstructive Surgery Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, Clinical Block, 8th Floor, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Ng MH; Centre for Tissue Engineering and Regenerative Medicine, Universiti Kebangsaan Malaysia Medical Centre, 12th Floor, Clinical Block, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, Malaysia.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 25; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*
Adipocytes/*cytology
Stem Cells/*cytology
Tissue Engineering/*methods
Urethra/*cytology
Ascorbic Acid/chemistry ; Biocompatible Materials/chemistry ; Culture Media ; Extracellular Matrix/metabolism ; Fibroblasts/cytology ; Gene Expression Profiling ; Humans ; Microscopy, Confocal ; Myocytes, Smooth Muscle/cytology ; Phenotype ; Proteomics ; Tissue Scaffolds/chemistry ; Urothelium/cytology ; Urothelium/metabolism
Czasopismo naukowe
Tytuł :
Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress.
Autorzy :
Mikeladze MA; Institute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.
Dutysheva EA; Institute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.
Kartsev VG; InterBioscreen, 142432 Chernogolovka, Russia.
Margulis BA; Institute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.
Guzhova IV; Institute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.
Lazarev VF; Institute of Cytology of the Russian Academy of Sciences, 194064 St. Petersburg, Russia.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 03; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*
Glioblastoma/*metabolism
Glyceraldehyde-3-Phosphate Dehydrogenases/*metabolism
HSP70 Heat-Shock Proteins/*metabolism
Animals ; Cell Line ; Cobalt ; Glioblastoma/physiopathology ; Glyceraldehyde-3-Phosphate Dehydrogenases/chemistry ; HEK293 Cells ; Humans ; Oxidation-Reduction ; Protein Aggregates ; Protein Binding ; Rats
Czasopismo naukowe
Tytuł :
To breathe or not to breathe? Hypoxia after pulsed-electric field treatment reduces the effectiveness of electrochemotherapy in vitro.
Autorzy :
Šilkūnas M; Department of Biology, Faculty of Natural Sciences, Vytautas Magnus University, 8 Vileikos str., LT-44404 Kaunas, Lithuania. Electronic address: .
Bavirša M; Department of Biology, Faculty of Natural Sciences, Vytautas Magnus University, 8 Vileikos str., LT-44404 Kaunas, Lithuania.
Saulė R; Department of Biology, Faculty of Natural Sciences, Vytautas Magnus University, 8 Vileikos str., LT-44404 Kaunas, Lithuania.
Batiuškaitė D; Department of Biology, Faculty of Natural Sciences, Vytautas Magnus University, 8 Vileikos str., LT-44404 Kaunas, Lithuania.
Saulis G; Department of Biology, Faculty of Natural Sciences, Vytautas Magnus University, 8 Vileikos str., LT-44404 Kaunas, Lithuania.
Pokaż więcej
Źródło :
Bioelectrochemistry (Amsterdam, Netherlands) [Bioelectrochemistry] 2021 Feb; Vol. 137, pp. 107636. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*
Antibiotics, Antineoplastic/*therapeutic use
Bleomycin/*therapeutic use
Carcinoma, Hepatocellular/*pathology
Electrochemotherapy/*methods
Liver Neoplasms/*pathology
Carcinoma, Hepatocellular/drug therapy ; Cell Line, Tumor ; Cell Survival ; Electrochemotherapy/standards ; Humans ; In Vitro Techniques ; Liver Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
A Simple Aggregation-Induced Emission Nanoprobe with Deep Tumor Penetration for Hypoxia Detection and Imaging-Guided Surgery in Vivo .
Autorzy :
Zhang Z; Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.
Wang R; Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.
Huang X; Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.
Zhu W; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 211198, China.
He Y; Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.
Liu W; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 211198, China.; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 211198, China.
Liu F; The Joint Laboratory of China Pharmaceutical University and Taian City Central Hospital, Taian City Central Hospital, Taian 271000, China.; Pharmaceutical Department, Taian City Central Hospital, Taian 271000, China.
Feng F; Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.; Jiangsu Food and Pharmaceutical Science College, Huaian 223003, China.
Qu W; Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China.; Key Laboratory of Biomedical Functional Materials, China Pharmaceutical University, Nanjing 211198, China.
Pokaż więcej
Źródło :
Analytical chemistry [Anal Chem] 2021 Jan 26; Vol. 93 (3), pp. 1627-1635. Date of Electronic Publication: 2020 Dec 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia*
Optical Imaging*
Carcinoma, Hepatocellular/*diagnostic imaging
Fluorescent Dyes/*chemistry
Liver Neoplasms/*diagnostic imaging
Animals ; Cell Line, Tumor ; Cytochrome P-450 Enzyme System/analysis ; Cytochrome P-450 Enzyme System/metabolism ; Fluorescent Dyes/chemical synthesis ; Humans ; Liver Neoplasms, Experimental/diagnostic imaging ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Impact of hypoxia on the double-strand break repair after photon and carbon ion irradiation of radioresistant HNSCC cells.
Autorzy :
Wozny AS; UMR CNRS5822/IN2P3, IP2I, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Univ Lyon, Université Lyon, 69921, Oullins Cedex, France.; Service de Biochimie et Biologie Moléculaire, Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, 69495, Pierre-Bénite, France.
Alphonse G; UMR CNRS5822/IN2P3, IP2I, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Univ Lyon, Université Lyon, 69921, Oullins Cedex, France.; Service de Biochimie et Biologie Moléculaire, Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, 69495, Pierre-Bénite, France.
Cassard A; UMR CNRS5822/IN2P3, IP2I, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Univ Lyon, Université Lyon, 69921, Oullins Cedex, France.
Malésys C; UMR CNRS5822/IN2P3, IP2I, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Univ Lyon, Université Lyon, 69921, Oullins Cedex, France.
Louati S; UMR CNRS5822/IN2P3, IP2I, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Univ Lyon, Université Lyon, 69921, Oullins Cedex, France.; Département de Radiothérapie, Institut de Cancérologie de la Loire Lucien Neuwirth, 42270, St Priest-en-Jarez, France.
Beuve M; UMR CNRS5822 /IN2P3, IP2I, PRISME, Univ Lyon, Université Lyon 1, 69322, Villeurbanne, France.
Lalle P; UMR CNRS5822/IN2P3, IP2I, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Univ Lyon, Université Lyon, 69921, Oullins Cedex, France.
Ardail D; UMR CNRS5822/IN2P3, IP2I, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Univ Lyon, Université Lyon, 69921, Oullins Cedex, France.; Service de Biochimie et Biologie Moléculaire, Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, 69495, Pierre-Bénite, France.
Nakajima T; Department of Radiation Effects Research, National Institute of Radiological Sciences, National Institute for Quantum and Radiological Science and Technology, Inage-ku, Chiba, 263-8555, Japan.
Rodriguez-Lafrasse C; UMR CNRS5822/IN2P3, IP2I, PRISME, Laboratoire de Radiobiologie Cellulaire et Moléculaire, Faculté de Médecine Lyon-Sud, Univ Lyon, Université Lyon, 69921, Oullins Cedex, France. .; Service de Biochimie et Biologie Moléculaire, Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, 69495, Pierre-Bénite, France. .
Pokaż więcej
Źródło :
Scientific reports [Sci Rep] 2020 Dec 07; Vol. 10 (1), pp. 21357. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia/*physiology
DNA Breaks, Double-Stranded/*radiation effects
Squamous Cell Carcinoma of Head and Neck/*genetics
Cell Cycle/genetics ; Cell Cycle/radiation effects ; Cell Hypoxia/genetics ; Cell Line, Tumor ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; Fluorescent Antibody Technique ; Genotype ; Heavy Ion Radiotherapy ; Humans ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/radiation effects ; Squamous Cell Carcinoma of Head and Neck/radiotherapy ; Tumor Microenvironment/genetics ; Tumor Microenvironment/radiation effects ; Tumor Suppressor Protein p53/genetics ; X-Rays
Czasopismo naukowe
Tytuł :
MicroRNA‑494 suppresses hypoxia/reoxygenation‑induced cardiomyocyte apoptosis and autophagy via the PI3K/AKT/mTOR signaling pathway by targeting SIRT1.
Autorzy :
Ning S; Laboratory of Cardiovascular Disease and Drug Research, Zhengzhou No. 7 People's Hospital, Zhengzhou, Henan 450016, P.R. China.
Li Z; Laboratory of Cardiovascular Disease and Drug Research, Zhengzhou No. 7 People's Hospital, Zhengzhou, Henan 450016, P.R. China.
Ji Z; Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Fan D; Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Wang K; Laboratory of Cardiovascular Disease and Drug Research, Zhengzhou No. 7 People's Hospital, Zhengzhou, Henan 450016, P.R. China.
Wang Q; Laboratory of Cardiovascular Disease and Drug Research, Zhengzhou No. 7 People's Hospital, Zhengzhou, Henan 450016, P.R. China.
Hua L; Laboratory of Cardiovascular Disease and Drug Research, Zhengzhou No. 7 People's Hospital, Zhengzhou, Henan 450016, P.R. China.
Zhang J; Laboratory of Cardiovascular Disease and Drug Research, Zhengzhou No. 7 People's Hospital, Zhengzhou, Henan 450016, P.R. China.
Meng X; Laboratory of Cardiovascular Disease and Drug Research, Zhengzhou No. 7 People's Hospital, Zhengzhou, Henan 450016, P.R. China.
Yuan Y; Department of Cardiovascular Internal Medicine, Henan Provincial Chest Hospital, Zhengzhou, Henan 450003, P.R. China.
Pokaż więcej
Źródło :
Molecular medicine reports [Mol Med Rep] 2020 Dec; Vol. 22 (6), pp. 5231-5242. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia/*genetics
MicroRNAs/*genetics
Myocytes, Cardiac/*metabolism
Animals ; Apoptosis/genetics ; Autophagy/genetics ; Cell Hypoxia/physiology ; Cell Line ; Hypoxia/genetics ; Hypoxia/metabolism ; MicroRNAs/metabolism ; Myocardial Infarction/metabolism ; Myocardial Reperfusion Injury/metabolism ; Myocytes, Cardiac/physiology ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Signal Transduction/drug effects ; Sirtuin 1/metabolism ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Selective colorimetric and fluorescence detection of nitroreductase enzymes in living cells.
Autorzy :
Mi Z; College of Life Science, Shanxi Datong University, Shanxi, Datong 037009, China.
Liu L; College of Chemistry and Engineering, Shanxi Datong University, Shanxi, Datong 037009, China. Electronic address: .
Zhao Y; School of Mechanical Engineering, Liaoning Shihua University, Fushun 113001, Liaoning, China.
Guan J; School of Mechanical Engineering, Liaoning Shihua University, Fushun 113001, Liaoning, China. Electronic address: .
Pokaż więcej
Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 01; Vol. 164, pp. 932-938. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*
Microscopy, Fluorescence*/methods
Colorimetry/*methods
Nitroreductases/*analysis
Cell Line, Tumor ; Fluorescence ; Fluorescent Dyes/chemistry ; HeLa Cells ; Humans ; Hydrogen-Ion Concentration ; Hydrolysis ; Rhodamines/chemistry
Czasopismo naukowe
Tytuł :
Proof-of-principle for two-stage photodynamic therapy: hypoxia triggered release of singlet oxygen.
Autorzy :
Ayan S; Department of Chemistry, Bilkent University, 06800, Ankara, Turkey.
Gunaydin G; Department of Basic Oncology, Hacettepe University, 06100, Ankara, Turkey.
Yesilgul-Mehmetcik N; UNAM-National Nanotechnology Research Center, Bilkent University, 06800, Ankara, Turkey. .
Gedik ME; Department of Basic Oncology, Hacettepe University, 06100, Ankara, Turkey.
Seven O; UNAM-National Nanotechnology Research Center, Bilkent University, 06800, Ankara, Turkey. .
Akkaya EU; State Key Laboratory of Fine Chemicals, Dalian University of Technology, 2 Linggong Road, 116024 Dalian, China. .
Pokaż więcej
Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Nov 26; Vol. 56 (94), pp. 14793-14796.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Hypoxia*
Photochemotherapy*
Singlet Oxygen/*chemistry
Humans ; MCF-7 Cells ; Photosensitizing Agents/pharmacology ; Proof of Concept Study
Czasopismo naukowe
Tytuł :
A Mitochondrion-Localized Two-Photon Photosensitizer Generating Carbon Radicals Against Hypoxic Tumors.
Autorzy :
Kuang S; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Sun L; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Zhang X; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Liao X; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Rees TW; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Zeng L; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Chen Y; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Zhang X; Department of Chemistry, University of Hong Kong, Pokfulam Road, Hong Kong S.A.R., P. R. China.
Ji L; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.
Chao H; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China.; MOE Key Laboratory of Theoretical Organic Chemistry and Functional Molecule, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, 400201, P. R. China.
Pokaż więcej
Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2020 Nov 09; Vol. 59 (46), pp. 20697-20703. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia*
Carbon/*chemistry
Mitochondria/*drug effects
Neoplasms/*drug therapy
Photosensitizing Agents/*pharmacology
Humans ; Mitochondria/metabolism ; NADP/metabolism ; Neoplasms/pathology ; Photochemotherapy/methods ; Photons ; Spectrum Analysis/methods ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Construction and investigation of a combined hypoxia and stemness index lncRNA-associated ceRNA regulatory network in lung adenocarcinoma.
Autorzy :
Guo L; Department of Medical Oncology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, No. 1 Beiguandajie, Tongzhou District, Beijing, 101149, China.
Li H; Department of Medical Oncology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, No. 1 Beiguandajie, Tongzhou District, Beijing, 101149, China.
Li W; Department of Cellular and Molecular Biology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing, 101149, China.
Tang J; Department of Medical Oncology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, No. 1 Beiguandajie, Tongzhou District, Beijing, 101149, China. .
Pokaż więcej
Źródło :
BMC medical genomics [BMC Med Genomics] 2020 Nov 04; Vol. 13 (1), pp. 166. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia*
Cell Self Renewal*
Gene Expression Regulation, Neoplastic*
Gene Regulatory Networks*
Adenocarcinoma of Lung/*genetics
Lung Neoplasms/*genetics
Neoplastic Stem Cells/*pathology
RNA, Long Noncoding/*genetics
RNA, Neoplasm/*genetics
Adenocarcinoma of Lung/metabolism ; Adenocarcinoma of Lung/mortality ; Cluster Analysis ; Datasets as Topic ; Humans ; Kaplan-Meier Estimate ; Lung Neoplasms/metabolism ; Lung Neoplasms/mortality ; MicroRNAs/genetics ; Prognosis ; RNA, Long Noncoding/biosynthesis ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; RNA, Neoplasm/biosynthesis ; RNA, Neoplasm/classification
Czasopismo naukowe
Tytuł :
Dual-Emissive Platinum(II) Metallacage with a Sensitive Oxygen Response for Imaging of Hypoxia and Imaging-Guided Chemotherapy.
Autorzy :
Zhu H; State Key Laboratory of Chemical Engineering, Center for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University, Hangzhou, 310027, P. R. China.; Department of Chemistry, University of Utah, Salt Lake City, UT, 84112, USA.
Li Q; State Key Laboratory of Chemical Engineering, Center for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University, Hangzhou, 310027, P. R. China.; Department of Chemistry, University of Utah, Salt Lake City, UT, 84112, USA.
Shi B; Department of Chemistry, University of Utah, Salt Lake City, UT, 84112, USA.
Ge F; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, P. R. China.
Liu Y; State Key Laboratory of Chemical Engineering, Center for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University, Hangzhou, 310027, P. R. China.
Mao Z; MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, P. R. China.
Zhu H; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, P. R. China.
Wang S; School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology, Tianjin, 300072, P. R. China.
Yu G; State Key Laboratory of Chemical Engineering, Center for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University, Hangzhou, 310027, P. R. China.
Huang F; State Key Laboratory of Chemical Engineering, Center for Chemistry of High-Performance & Novel Materials, Department of Chemistry, Zhejiang University, Hangzhou, 310027, P. R. China.; Green Catalysis Center and College of Chemistry, Zhengzhou University, Zhengzhou, 450001, P. R. China.
Stang PJ; Department of Chemistry, University of Utah, Salt Lake City, UT, 84112, USA.
Pokaż więcej
Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2020 Nov 02; Vol. 59 (45), pp. 20208-20214. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia*
Antineoplastic Agents/*therapeutic use
Neoplasms/*metabolism
Oxygen/*analysis
Platinum/*chemistry
Fluorescence Resonance Energy Transfer ; Humans ; Neoplasms/diagnosis ; Neoplasms/drug therapy ; Neoplasms/pathology ; Precision Medicine ; Spectrophotometry, Ultraviolet
Czasopismo naukowe
Tytuł :
Inhibition of IRE1/JNK pathway in HK-2 cells subjected to hypoxia-reoxygenation attenuates mesangial cells-derived extracellular matrix production.
Autorzy :
Liang Y; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.
Liang L; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, China.; Core Unit of National Clinical Medical Research Center of Kidney Disease, Zhengzhou, China.
Liu Z; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.
Wang Y; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, China.; Core Unit of National Clinical Medical Research Center of Kidney Disease, Zhengzhou, China.
Dong X; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, China.; Core Unit of National Clinical Medical Research Center of Kidney Disease, Zhengzhou, China.
Qu L; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.
Gou R; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.
Wang Y; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.
Wang Q; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.; Department of Geriatrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Liu Z; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.; Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province, Zhengzhou, China.; Core Unit of National Clinical Medical Research Center of Kidney Disease, Zhengzhou, China.
Tang L; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Research Institute of Nephrology, Zhengzhou University, Zhengzhou, China.
Pokaż więcej
Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2020 Nov; Vol. 24 (22), pp. 13408-13420. Date of Electronic Publication: 2020 Oct 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia*
Endoribonucleases/*metabolism
Extracellular Matrix/*metabolism
JNK Mitogen-Activated Protein Kinases/*metabolism
Mesangial Cells/*metabolism
Oxygen/*metabolism
Protein-Serine-Threonine Kinases/*metabolism
Signal Transduction/*drug effects
Acute Kidney Injury/etiology ; Acute Kidney Injury/metabolism ; Acute Kidney Injury/pathology ; Biomarkers ; Cytokines/metabolism ; Disease Progression ; Disease Susceptibility ; Endoplasmic Reticulum Stress ; Fluorescent Antibody Technique ; Gene Knockdown Techniques ; Humans ; Inflammation Mediators/metabolism ; Mesangial Cells/ultrastructure ; RNA, Small Interfering/genetics ; Renal Insufficiency, Chronic/etiology ; Renal Insufficiency, Chronic/metabolism ; Renal Insufficiency, Chronic/pathology ; STAT3 Transcription Factor/metabolism ; Transcription Factor CHOP/metabolism
Czasopismo naukowe
Tytuł :
The Shc protein Rai enhances T-cell survival under hypoxia.
Autorzy :
Criscuoli M; Cellular and Molecular Physiology Unit, Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Ulivieri C; Department of Life Sciences, University of Siena, Siena, Italy.
Filippi I; Cellular and Molecular Physiology Unit, Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.; Istituto Toscano Tumori, Firenze, Italy.
Monaci S; Cellular and Molecular Physiology Unit, Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Guerrini G; Cellular and Molecular Physiology Unit, Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Crifò B; Department of Systems Biology, UCD Conway Institute and School of Medicine, University College Dublin, Dublin, Ireland.
De Tommaso D; Department of Life Sciences, University of Siena, Siena, Italy.
Pelicci G; Department of Experimental Oncology, European Institute of Oncology IRCCS, Milan, Italy.; Department of Translational Medicine, Piemonte Orientale University 'Amedeo Avogadro', Novara, Italy.
Baldari CT; Department of Life Sciences, University of Siena, Siena, Italy.
Taylor CT; Department of Systems Biology, UCD Conway Institute and School of Medicine, University College Dublin, Dublin, Ireland.
Carraro F; Istituto Toscano Tumori, Firenze, Italy.; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Naldini A; Cellular and Molecular Physiology Unit, Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Pokaż więcej
Źródło :
Journal of cellular physiology [J Cell Physiol] 2020 Nov; Vol. 235 (11), pp. 8058-8070. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Hypoxia/*genetics
Hypoxia-Inducible Factor 1, alpha Subunit/*genetics
Neuroblastoma/*genetics
T-Lymphocytes/*metabolism
Trans-Activators/*genetics
Animals ; Apoptosis/genetics ; Caspases/genetics ; Cell Hypoxia/immunology ; Cell Survival/genetics ; Glucose/metabolism ; Humans ; Jurkat Cells ; Lactic Acid/metabolism ; Mice ; Mice, Knockout ; Neuroblastoma/immunology ; Neuroblastoma/pathology ; Phosphorylation ; Proto-Oncogene Proteins c-akt/genetics ; T-Lymphocytes/immunology ; T-Lymphocytes/pathology
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies